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Document C(2025)8493

COMMISSION IMPLEMENTING DECISION on the financing of the Specific Programme implementing Horizon Europe – the Framework Programme for Research and Innovation – and the adoption of the work programme for 2026-2027

C/2025/8493 final

COMMISSION IMPLEMENTING DECISION

of 11.12.2025

on the financing of the Specific Programme implementing Horizon Europe – the Framework Programme for Research and Innovation – and the adoption of the work programme for 2026-2027

THE EUROPEAN COMMISSION,

Having regard to the Treaty on the Functioning of the European Union,

Having regard to Regulation (EU, Euratom) 2024/2509 of the European Parliament and of the Council of 23 September 2024 on the financial rules applicable to the general budget of the Union 1 , and in particular Article 110(1) thereof,

Having regard to Regulation (EU) 2021/695 of the European Parliament and of the Council of 28 April 2021 establishing Horizon Europe – the Framework Programme for Research and Innovation, laying down its rules for participation and dissemination, and repealing Regulations (EU) No 1290/2013 and (EU) No 1291/2013 2

Having regard to Council Decision (EU) 2021/764 of 10 May 2021 establishing the Specific Programme implementing Horizon Europe – the Framework Programme for Research and Innovation, and repealing Decision 2013/743/EU 3 , and in particular Article 13(2), point (b), thereof,

Whereas:

(1)In order to ensure the implementation of Council Decision (EU) 2021/764 (‘the Specific Programme’), it is necessary to adopt a multiannual financing decision, which is to constitute the multiannual work programme, for 2026 and 2027 for the Horizon Europe Programme, in accordance with Article 110(2) of Regulation (EU, Euratom) 2024/2509 (‘the Financial Regulation’).

(2)The work programme 2026-2027 covers the following parts: 1. ‘General Introduction’, 2. ‘Marie Skłodowska-Curie Actions’, 3. ‘Research Infrastructures’, 4. ‘Health’, 5. ‘Culture, Creativity and Inclusive Society’, 6. ‘Civil Security for Society’, 7. ‘Digital, Industry and Space’, 8. ‘Climate, Energy and Mobility’, 9. ‘Food, Bioeconomy, Natural Resources, Agriculture and Environment’, 10. ‘European Innovation Ecosystems’, 11. ‘Widening participation and strengthening the European Research Area’, 12. ‘Missions’, 13. ‘New European Bauhaus Facility’, 14. ‘Horizontal Activities’ and 15. ‘General Annexes’.

(3)The envisaged assistance is to comply with the conditions and procedures set out by the restrictive measures 4 adopted pursuant to Article 215 of the Treaty on the Functioning of the European Union.

(4)It is necessary to allow for the payment of interest due for late payment on the basis of Article 116(5) of the Financial Regulation.

(5)In order to allow for flexibility in the implementation of the work programme, it is appropriate to determine the changes, which should not be considered substantial for the purposes of Article 110(5) of the Financial Regulation.

(6)The activities should contribute to climate and biodiversity mainstreaming in line with the Commission Communication ‘The European Green Deal’ 5 and the Interinstitutional Agreement of 16 December 2020 on budgetary discipline, on cooperation in budgetary matters and on sound financial management, as well as on new own resources, including a roadmap towards the introduction of new own resources 6 . Part 1. ‘General Introduction’ provides more detail on the work programme’s contribution to climate and biodiversity mainstreaming.

(7)Pursuant to Article 62(1), first subparagraph, point (c), of the Financial Regulation, indirect management is to be used for the actions specified in the work programme.

(8)The Commission is to ensure a level of protection of the financial interests of the Union with regard to persons and entities entrusted with the implementation of Union funds by indirect management as provided for in Article 157(3) of the Financial Regulation. To that end, and before a contribution agreement can be signed, such persons and entities are to be subject to an assessment of their systems and procedures in accordance with Article 157(4) of the Financial Regulation and, if necessary, to appropriate supervisory measures in accordance with Article 157(5) of the Financial Regulation.

(9)It is necessary to authorise the award of grants without a call for proposals and to provide for the conditions for awarding those grants in accordance with Article 198 points (b), (e) and (f) of the Financial Regulation.

(10)It is necessary to protect the security and public order of the Union or its Member States as provided for in Article 136 of the Financial Regulation.

(11)The maximum Union contribution for the implementation of the Specific Programme in 2026 includes part of the EFTA States contribution which is fixed for 2026 at 2.60% of the appropriations. The maximum Union contribution for the implementation of the Specific Programme in 2027 includes part of the EFTA States contribution which is fixed for 2027 at 2.60% of the appropriations.

(12)The measures provided for in this Decision are in accordance with the opinion of the Programme Committee established by Article 14 of Council Decision (EU) 2021/764.

HAS DECIDED AS FOLLOWS:

Article 1

The work programme

The multiannual financing decision, constituting the multiannual work programme for the implementation of the Specific Programme for 2026 and 2027, as set out in Annexes I to XV to this Decision, is hereby adopted.

Article 2

Union contribution

The maximum Union contribution for the implementation of the Specific Programme, as covered by the work programme set out in Annexes I to XV to this Decision for 2026 and 2027, is set at EUR 7 244 901 854 for 2026 and EUR 7 005 883 042 for 2027, and shall be financed from the appropriations entered in the following lines of the general budget of the Union: 

(a) budget line 01.020102:

EUR 1 196 863 977 for 2026

EUR 1 181 629 855 for 2027

(b) budget line 01.020103:

EUR 311 200 000 for 2026

EUR 406 700 000 for 2027

(c) budget line 01.020210:

EUR 732 002 923 for 2026

EUR 845 097 812 for 2027

(d) budget line 01.020220:

   EUR 360 300 000 for 2026

EUR 337 400 000 for 2027

(e) budget line 01.020230:

EUR 190 130 000 for 2026

EUR 203 621 000 for 2027

(f) budget line 01.020240:

EUR 1 308 970 000 for 2026

EUR 1 256 550 000 for 2027

(g) budget line 01.020250:

EUR 1 712 693 445 for 2026

EUR 1 384 285 673 for 2027

(h) budget line 01.020260:

EUR 918 711 509 for 2026

EUR 884 558 702 for 2027

(i) budget line 01.020302:

EUR 29 000 000 for 2026

EUR 36 100 000 for 2027

(j) budget line 01.020401:

EUR 410 875 000 for 2026

EUR 415 340 000 for 2027

(k) budget line 01.020402:

EUR 74 155 000 for 2026

EUR 54 600 000 for 2027

(l) the following budget lines (transferred resources used for the benefit of a Member State concerned in accordance with Article 15(5) of Regulation (EU) 2021/695):

05.020900 — Horizon Europe — Contribution from the European Regional Development Fund (ERDF)

05.030700 — Horizon Europe — Contribution from the Cohesion Fund (CF)

EUR 0 7 for 2026 and 2027

The appropriations provided for in the first paragraph may also cover interest due for late payment.

The implementation of this Decision is subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027 following the adoption of that budget by the budget authority.

Article 3

Flexibility clause

Cumulated changes to the allocations to specific actions not exceeding 20% of the maximum Union contribution set in Article 2, first paragraph, of this Decision shall not be considered to be substantial for the purposes of Article 110(5) of the Financial Regulation, where those changes do not significantly affect the nature of the actions and the objective of the work programme. The increase of the maximum Union contribution set in Article 2, first paragraph, of this Decision shall not exceed 20%.

The authorising officer responsible may apply the changes referred to in the first paragraph. Those changes shall be applied in accordance with the principles of sound financial management and proportionality.

Article 4

Methods of implementation and entrusted entities or persons

The implementation of the actions carried out by way of indirect management, as set out in Annexes VI, VII, VIII, IX and XII to this Decision, may be entrusted to the entities referred to in those Annexes.

Article 5

Grants awarded without a call for proposals

Grants may be awarded without a call for proposals in accordance with the conditions set out in Annexes II, III, IV, V, VII, VIII, IX, XI, XII and XIII to this Decision.

Article 6

Security and public order

In accordance with Article 136(2) of the Financial Regulation, the actions set out in Annexes VII and VIII to this Decision have been identified as affecting the security and public order of the Union or its Member States.

In accordance with Article 136(3) of the Financial Regulation, the authorising officer responsible may set specific conditions for the award procedures and for the resulting legal commitments. The specific conditions shall be strictly limited to what is necessary to protect security or public order of the Union and/or its Member States.

Article 7

Financial instruments

The provision of financial support by means of blending operations under InvestEU for the amount set in Annex VII, may be entrusted to the entity referred to in the Annex VII.

Done at Brussels, 11.12.2025

   For the Commission

   Ekaterina ZAHARIEVA
   Member of the Commission

(1)    OJ L, 2024/2509, 26.9.2024, ELI: http://data.europa.eu/eli/reg/2024/2509/oj .
(2)    OJ L 170, 12.5.2021, p. 1, ELI: http://data.europa.eu/eli/reg/2021/695/oj .    
(3)    OJ L 167I, 12.5.2021, p. 1, ELI: http://data.europa.eu/eli/dec/2021/764/oj .
(4)    See www.sanctionsmap.eu – Note that the sanctions map is an IT tool for identifying the sanctions regimes. The source of the sanctions stems from legal acts published in the Official Journal (OJ). In the case of discrepancy, the OJ prevails.
(5)    COM (2019) 640 final of 11 December 2019.    
(6)    Interinstitutional Agreement of 16 December 2020 between the European Parliament, the Council of the European Union and the European Commission on budgetary discipline, on cooperation in budgetary matters and on sound financial management, as well as on new own resources, including a roadmap towards the introduction of new own resources (OJ L 433I , 22.12.2020, p. 28, ELI:  http://data.europa.eu/eli/agree_interinstit/2020/1222/oj ).
(7)    Without prejudice to the maximum Union contribution of EUR 7 244 901 854 for 2026 and EUR 7 005 883 042 for 2027 or budget flexibility covered by Article 3 of this Decision, the Union contribution may be financed from appropriations entered into these budget lines.
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EN

Annex I

Horizon Europe

Work Programme 2026-2027

1.General Introduction

   

About this work programme

Horizon Europe funds research and innovation (R&I), especially through work programmes, which set out funding opportunities for R&I activities 1 .

This introduction covers the following parts of Horizon Europe for 2026-2027:

·Marie Skłodowska-Curie Actions,

·Research Infrastructures,

·Health,

·Culture, Creativity and Inclusive Society,

·Civil Security for Society,

·Digital, Industry and Space,

·Climate, Energy and Mobility,

·Food, Bioeconomy, Natural Resources, Agriculture and Environment,

·European Innovation Ecosystems,

·Widening participation and spreading excellence, and reforming and enhancing the European R&I system,

·EU Missions,

·New European Bauhaus Facility 

·Horizontal activities: calls for the Clean Industrial Deal and on artificial intelligence (AI).

In addition to the work programme parts listed above, the general annexes to this work programme set out the general conditions applicable to calls for proposals under this work programme, such as eligibility rules, details on how to apply and how the Commission evaluates applications.

Getting started

If you are interested in applying for funding through Horizon Europe, you can find all topics that are currently open for applications on the Funding and Tenders Portal , now also accessible via mobile app . To help you navigate the application process, the network of National Contact Points is available to answer your questions and provide support in your own language.

You can also find out more about the Horizon Europe programme on the Horizon Europe web page .

Key novelties

Simplification measures

The Commission is committed to making the Horizon Europe work programme even simpler, shorter and more impactful. This work programme introduces several measures aimed at simplifying processes, enhancing transparency and inclusiveness. The key simplification measures in this work programme are set out below.

·Less prescriptive topic descriptions. The average length of topic descriptions has been reduced, making these less prescriptive and thereby allowing applicants more flexibility in how they approach the topics. This includes more open topics 2 introduced across clusters in Pillar II. This also means that the overall length of the Work Programme 2026-2027 has been reduced by 33% compared with the Work Programme 2023-2024.

·Fewer topics. The number of topics has been reduced by 35% compared with the Work Programme 2023-2024. This streamlining is intended to focus resources on fewer but larger topics, thereby increasing the potential impact. Moreover, the number of topics funding only one project has been decreased by 50%.

·Increased use of lump-sum funding. 50% of the call budget of this work programme will be implemented through lump sums. This particularly concerns topics intended to result in grants below EUR 10 million. The use of lump sums simplifies financial management and reduces administrative burden for participants.

·‘Newcomer-friendly’ and SME-friendly topics. This work programme includes topics that are specifically designed to be newcomer-friendly, encouraging participation by SMEs, start-ups and scale-ups, civil society organisations and small public administrations. These topics can, for instance, use the Fast Track to Research and Innovation Scheme. Similarly, there are more topics that allow for financial support to third parties  than in previous work programmes.

·Use of two-stage calls. The programme includes 41 call topics with two-stage evaluation. These will allow applicants to submit a shorter summary proposal and only submit a full proposal if successful at the stage of the short proposal evaluation. Many of these short proposals will be evaluated blindly, thanks to anonymised applications, as a way to avoid potential risk of bias. By reducing the submission period for first-stage proposals and simplifying evaluation processes, the time to grant is shortened.

·Reduced complexity of proposal template. Standard templates for the most common type of actions have been updated, simplifying the requirements for the impact and implementation sections and reducing the overall page limits.

These measures collectively aim to make the work programme more efficient, accessible and impactful by reducing administrative burdens and promoting inclusivity and innovation.

Horizontal calls

A key novelty in this work programme is the introduction of horizontal calls, which are designed to connect different parts of Horizon Europe in support of key strategic areas. These calls ensure that Horizon Europe is more in tune with the EU’s evolving policies by tackling them in a consistent, cross-cluster, multidisciplinary way. By combining efforts and pooling resources, they aim to create critical mass and deliver greater impact. The horizontal calls are built around open, broadly defined topics guided by a shared strategic direction. The topics are intentionally non-prescriptive, giving applicants the flexibility to propose different approaches for achieving the expected outcomes.

R&I in Support of the Clean Industrial Deal

The horizontal call ‘R&I in Support of the Clean Industrial Deal’, set out in the ‘Horizontal Activities’ part of this work programme, is designed to implement the EU’s commitments under the Clean Industrial Deal through targeted research and innovation. With an indicative budget of EUR 540 million, this call aims to accelerate the market deployment of cutting-edge clean technologies and decarbonised industry solutions, with a focus on both technological excellence and market readiness.

The call takes a bottom-up, industry-led approach, facilitating cross-sectoral integration and market-driven R&I responses. It consists of two large, open topics focusing on: (1) decarbonisation of energy-intensive industries; and (2) clean technologies for climate action. The focus is on creating ‘fit-for-deployment’ projects that not only are technologically feasible but also have robust business and market readiness strategies.

As announced in the Clean Industrial Deal Communication , this call will foster synergies between Horizon Europe and the Innovation Fund by ensuring a continuous pipeline of R&I solutions ready for market deployment. Ultimately, the call seeks to accelerate the roll-out of clean tech solutions, boost European competitiveness, mobilise investments and reduce energy prices, thereby contributing significantly to the EU’s industrial decarbonisation and clean energy objectives.

AI in Science

The horizontal call ‘AI in Science’, set out in the ‘Horizontal Activities’ part of this work programme, is aimed at fostering trustworthy AI solutions to tackle significant societal and industrial challenges. It contributes to the implementation of the ‘Resource for AI Science in Europe’ (RAISE) pilot, as announced in the European Strategy for Artificial Intelligence in Science . This call supports safe, responsible, ethical and transparent AI applications across key sectors, such as advanced materials, agriculture, environment and food, and is in line with Europe’s broader digital transition goals. By embedding these innovations, this work programme seeks to enhance Europe’s R&I leadership, thereby having a substantial impact on sustainability, digital innovation and inclusive growth.

With an indicative budget of around EUR 90 million, this call includes open topics on thematic networks of excellence for AI in science, automated scientific discovery and RAISE doctoral networks for AI in science. These topics are designed to apply across different R&I areas within the work programme, ensuring a cohesive and comprehensive approach to advancing AI science in Europe. Through these initiatives, the call not only supports safe, secure and trustworthy technological advancement but also strengthens Europe’s strategic position in the global AI landscape.

In parallel to this horizontal call, at least EUR 775 million will be invested in AI in science through the rest of this work programme.

Choose Europe for Science

The Choose Europe for Science initiative is an important element of the Horizon Europe Work Programme 2026-2027 and is designed to make Europe a premier destination for scientific careers. The Choose Europe for Science initiative aligns closely with broader EU goals, emphasising the need to foster innovation by creating an environment where researchers can thrive. By offering stable funding opportunities and access to cutting-edge facilities, the EU enables researchers to tackle some of the world’s most pressing challenges. On top of the EUR 500 million announced in May 2025 for this initiative, this work programme brings in additional resources.

Building on the 2025 pilot aiming to promote research careers in Europe by funding postdoctoral programmes that go beyond project-based work, the Marie Skłodowska-Curie Actions (MSCAs) part of this work programme allocates about EUR 50 million to improve long-term fellowships, ensure postdoctoral career stability and offer relocation incentives. By linking MSCA grants to competitions for long-term positions in universities and research organisations, this initiative underscores the EU’s commitment to providing excellent research opportunities, working conditions and long-term professional prospects, thereby ensuring that Europe remains a hub for top talent and groundbreaking scientific advancements.

In addition to the dedicated ‘Choose Europe for Science’ initiative under the MSCA, this work programme also supports these objectives through other actions across its various components. For instance, by strengthening Europe’s world-class research infrastructures – including through improving transnational access to their facilities and services, supporting training and upskilling, and reinforcing their international dimensions – the programme contributes to stimulate researchers and innovators to ‘Choose Europe for Science’. Such contributions represent nearly EUR 50 million in the Research Infrastructures part of this work programme. In addition, the ERA Chairs call, aiming to attract high-level researchers to a widening university or research centre, also supports the initiative with a budget of EUR 240 million. Moreover, in light of the adopted EU Startup and Scaleup strategy, the European Innovation Ecosystem supports the ‘Choose Europe for Science’ initiative by creating conditions favourable for the growth of global, technology-driven companies.

Delivering on EU policy priorities

Europe has made its choice. We are choosing to start a new age of invention and ingenuity. We are choosing to put research and innovation, science and technology at the heart of our economy. We are choosing to be the continent where science is a pillar of our society and our way of life.

Europe’s global competitiveness and leadership in the clean and digital transitions remain central to the future. These transitions hinge on a bold, coordinated approach to R&I which fuels scientific breakthroughs, accelerates the development of critical technologies and addresses pressing societal challenges.

With this work programme, the EU and the countries associated to Horizon Europe will invest over EUR 14 billion in research and innovation to enhance Europe’s sustainable prosperity and competitiveness. Building on the previous Horizon Europe work programmes, it introduces significant new initiatives designed to tackle the most pressing EU challenges and priorities, including the Clean Industrial Deal and advancements in AI. The EU’s shift to a circular economy is also integral to the work programme for 2026-2027, with a focus on systemic changes across sectors such as construction and textiles and promoting innovative, market-ready solutions through high-impact, cross-cluster actions. Alongside initiatives under the Clean Industrial Deal to help increase circularity in energy-intensive industries and clean tech, the Circular Cities and Regions Initiative will focus on local and regional authorities, fostering place-based innovation and experimentation. A further example of a key EU strategy supported by this work programme is the Strategy for European Life Sciences

Amid ongoing geopolitical uncertainties, including conflicts in Europe and the Middle East, this work programme will focus on initiatives that strengthen Europe’s security, reduce strategic dependencies and reinforce supply chain resilience. For instance, EUR 634 million is allocated to topics related to critical raw materials, and the programme also supports research on advanced materials and alternatives to rare earth. By investing in critical technologies – such as energy technologies, quantum and advanced manufacturing – the EU aims to safeguard its strategic autonomy while fostering economic growth and social cohesion. This work programme is a key step towards achieving the priorities outlined in the second Horizon Europe strategic plan (2025-2027) . The actions set out in this work programme are expected to substantially contribute to the three overarching, interlinked key strategic orientations: the green transition, the digital transition and a more resilient, competitive, inclusive and democratic Europe. These orientations are fully aligned with the EU’s main policy priorities, as set out in the Commission’s Political Guidelines for 2024-2029 and expanded on in the  Competitiveness Compass for the EU , all of which require significant contributions from R&I to meet their objectives.

Knowledge valorisation is also a key priority of this work programme. Over EUR 870 million is allocated to valorisation topics on market, societal and policy uptake of research results. Other topics across the work programme also include valorisation elements.

To support the European strategy on research and technology infrastructures , the Research Infrastructures part of this work programme aims to strengthen research infrastructures so that they can support all stages of the innovation process – from basic research to real-world use in the market. This approach aims to ensure that Europe remains competitive on the global stage.

In particular, the Research Infrastructures part will contribute to enriching the European Open Science Cloud Federation with high-quality, FAIR 3 research data and scientific tools and services that support cross-disciplinary science cases.

R&I activities under Cluster 1 ‘Health’ will support healthcare resilience, leverage biotechnology and AI and address key public health needs – including mental health, disease prevention, pollution- and climate-related health impacts and the development of critical medicines and medical countermeasures. These efforts will help improve health outcomes, ease the burden of disease and contribute to Europe’s sustainable prosperity and global competitiveness, supporting the goal of making the EU the most attractive place for life sciences by 2030, in line with the  Strategy for European Life Sciences .  This cluster will also develop innovative interventions to prevent the harmful effects of digital technologies on the mental health of children and young adults, in line with the Commission’s objective to protect their mental health in an increasingly digitalised world.

The mobilisation of social sciences and humanities and interdisciplinary R&I under the actions in Cluster 2 ‘Culture, Creativity and Inclusive Society’ will help foster a democratic culture of participation and inclusivity and promote the values of equality, freedom, respect for human dignity and human rights and respect for cultural pluralism. Research will ensure that these EU values remain relevant in addressing contemporary challenges and in balancing technological progress with its societal impact. This will contribute to a more inclusive and equitable Europe, where innovation benefits all, particularly those at risk of being excluded or discriminated against by technological changes.

A new European partnership on social transformations and resilience, focusing on social sciences and humanities, will be launched under Cluster 2 of the work programme. The partnership will fund R&I activities in the following areas: the future of work, modernisation of social protection and essential services, education and skills development, and a fair transition towards climate neutrality. This is the last of the nine new European partnerships announced in the second Horizon Europe strategic plan (2025-2027) and it is aimed at combining national R&I efforts and increasing industry participation in Horizon Europe in key strategic areas.

Actions in Cluster 3 ‘Civil Security for Society’ will contribute to a safer and more secure Europe, a ‘Preparedness Union’ and stronger common borders, thereby protecting democracy and putting R&I at the heart of a resilient economy. This cluster will equip security practitioners, such as law enforcement and critical infrastructure operators, with modern tools consistent with EU values, while boosting European competitiveness and promoting innovation procurement. This cluster supports the  ProtectEU strategy  in addressing threats such as terrorism and cybercrime and will facilitate secure border crossings for people and goods. It also contributes to the European Preparedness Union Strategy  for better managing risks, developing a European Civil Defence Mechanism for crisis management, and strengthening the EU’s cyber resilience through advanced protective measures and international collaboration. Overall, this cluster focuses on ensuring people’s right to safety.

This work programme continues to support the digital transition to clean industry and autonomous access to space in a competitive, strategically autonomous Europe. In line with this, as key priorities, actions in Cluster 4 ‘Digital, Industry and Space’ will focus on ensuring a substantial and coordinated contribution by R&I to the Clean Industrial Deal, promoting emerging enabling technologies, such as AI in science, and achieving open strategic autonomy 4 in space-based infrastructure, services, applications and data. In doing so, this cluster operates in alignment with the previously mentioned horizontal calls focused on the Clean Industrial Deal and AI in Science. This cluster will also help build synergies and joint activities between partnerships.

Cluster 5 ‘Climate, Energy and Mobility’ will support R&I on decarbonising our economy and society, promoting a more sustainable approach to production and consumption, and advancing our knowledge on climate science. These actions will help identify effective and efficient pathways, cross-cutting technologies, and solutions to address climate change mitigation and adaptation, energy needs and mobility challenges. Efforts will focus on ensuring affordable, sustainable and secure energy supplies, the shift to more sustainable mobility options and transport modes, the decarbonisation of industry, and circularity in manufacturing and process industries. R&I will also leverage digital technologies to improve productivity and help to close the skills gap, thereby improving Europe’s competitiveness.

The Industrial Action Plan for the European automotive sector is supported through multiple actions in Cluster 5, including a flagship topic on large-scale demonstration of connected, cooperative and automated mobility. Further aligning with this action plan, the European Commission has launched a strategic Memorandum of Understanding with the European co-programmed partnerships linked to the automotive sector 5 to accelerate R&I in sustainable and smart mobility.

Cluster 6 ‘Food, Bioeconomy, Natural Resources, Agriculture and Environment’ is pivotal for sustaining our quality of life, from food security to water and nature. Actions in this cluster are expected to support the implementation of the common agricultural policy and the vision for agriculture and food , among others. To protect our natural world, Cluster 6 is aimed at developing innovations to facilitate the effective implementation of the Nature Restoration Regulation , including by addressing the main drivers of biodiversity loss. This cluster also addresses pollution and various water-related challenges in support of the European Water Resilience Strategy  and helps protect and restore ocean health to deliver on the  European Ocean Pact .  It pursues climate adaptation and mitigation by helping land- and water-based sectors to transition towards climate neutrality by 2050, as required by the European Climate Law.

Actions in Cluster 6 are expected to accelerate the transition towards a more circular, nature-positive and resilient economy and bioeconomy and to foster bio-based products and value chains in support of the Competitiveness Compass, the Clean Industrial Deal, the Strategy for European Life Sciences and the bioeconomy strategy.

The European Innovation Ecosystems (EIE) programme enhances interconnected innovation ecosystems across the EU. It contributes to boosting Europe’s innovation capabilities, notably in the deep tech sector, and improving the commercialisation of research. By fostering synergies among diverse innovation actors, the EIE programme contributes to the EU’s goals of achieving a green and digital transition, enhancing competitiveness and fostering social cohesion. It also aims to support startups and scaleups within the EU to strengthen economic resilience and strategic autonomy.

To help European deep tech startups to scale into global champions, the European Startup and Scaleup Hubs initiative under the EIE programme aims to create a network connecting Europe’s leading and emerging startups. This pilot action, which is part of the Startup and Scaleup Strategy , will promote a transnational network of hubs rooted in strong research and higher education systems, bringing together research facilities, companies, entrepreneurs and investors and providing dedicated support to deep tech spin offs, startups and scaleups.

As outlined in the European Research Area (ERA) Policy Agenda 2025-2027 , the ERA is envisaged as an integrated and competitive environment for research and innovation across the EU, driven by excellence and openness. The ‘Widening participation and strengthening the European Research Area’ work programme part supports the ERA’s goals by addressing fragmentation of R&I, reducing geographical disparities between countries and enhancing R&I capacity 6 , thus helping to achieve the target of spending 3% of GDP on research and development in the EU. Notable initiatives include ERA Chairs, which attract top scientists and innovators to countries with a lower R&I performance to foster excellence and institutional reforms, thereby enhancing competitiveness and talent retention. Given the increased budget for this work programme, these actions now also include recruiting leading research managers to boost research management capacities, thereby supporting effective resource allocation and strategic planning. Additionally, under this work programme part, the ‘Talent ecosystems for attractive early research careers’ topic promotes the new European framework for research careers, contributing to better working conditions and stability for researchers, aligning with the ‘Choose Europe for Science’ initiative and enhancing the EU’s appeal to both European and international talent.

EU Missions address by definition major global challenges through ambitious, time-bound objectives rooted in transdisciplinary research and innovation. They encompass various disciplines and policies, supporting key EU priorities such as the European Clean Industrial Deal, Europe’s Beating Cancer Plan, the EU industrial strategy and the digital transition. The EU Missions work programme part fosters synergies with other Horizon Europe funding instruments and includes actions for all five EU Missions:

·Adaptation to Climate Change: helping at least 150 European regions and communities to become climate resilient by 2030;

·Cancer: improving the lives of more than 3 million people by 2030 through prevention and cure, and helping those affected by cancer, including their families, to live longer and better;

·Restore our Ocean and Waters by 2030: protecting and restoring aquatic ecosystems, eliminating pollution, and making the blue economy circular and carbon-neutral;

·Climate-Neutral and Smart Cities: delivering 100 climate-neutral and smart cities by 2030;

·A Soil Deal for Europe: setting up 100 living labs and lighthouses to lead the transition towards healthy soils by 2030.

In particular, this work programme aims to enhance local and regional climate risk preparedness, provide solutions to restore EU waters, establish Climate City Contracts with 100 cities, create a unified framework for soil-health monitoring and innovative tools for land managers, and support cancer prevention through clinical trials for treatments and biomarker-guided medicines. The Commission is further launching a Mission integration award and a Mission engagement award to encourage and recognise national and regional authorities in their efforts to implement and engage with EU Missions.

As a cross-cluster issue, the New European Bauhaus Facility leverages the power of inclusion, sustainability, and arts and culture in R&I to advance the Green Deal and clean transition in neighbourhoods and their communities. More specifically, it fosters R&I solutions aimed at connecting the green transformation, social inclusion and local democracy and advancing circular and regenerative approaches to the built environment, while also developing innovative funding and new business models for the transformation of neighbourhoods.

This work programme emphasises the crucial role of international cooperation in addressing global challenges and advancing EU policy priorities, including those under the Global Gateway , particularly in the areas of climate, health and digital transition. In line with the political guidelines prioritising a global Europe that leverages its power and partnerships, this programme underscores the EU’s commitment to leading the green and digital transitions and tackling health and environmental challenges at the right level, in accordance with agreements such as the Kunming-Montreal Global Biodiversity Framework . By working together with international partners, the EU can more effectively address its strategic dependencies in critical sectors. The second Horizon Europe strategic plan (2025-2027) further emphasises that international cooperation remains the foundation of the EU’s efforts to make Europe more resilient and stronger in the world. All sections of this work programme actively encourage international collaboration, with a particular focus on initiatives involving Africa, the Mediterranean, Latin America and the Caribbean countries, and increased collaboration with India and South-East Asian nations.

The association of third countries to Horizon Europe is a significant component of this approach. Currently, 22 countries are associated to the programme. Ongoing discussions with other nations highlight the political, economic and scientific importance of association to Horizon Europe. For example, association is strategic for strengthening our partnerships in the EU’s neighbouring regions and, in the case of candidate countries, paves the way for accession by helping to align R&I efforts. Several topics in this work programme contribute directly or indirectly to the reconstruction and recovery of Ukraine’s R&I sector, Ukraine’s integration into the European Research Area or the reconstruction and recovery of another R&I related sector. More generally, association provides a robust framework for deepening science and technology cooperation with external partners, in line with the European Economic Security Strategy .

Investing in climate action, biodiversity and the digital transition

To achieve the aim of making the EU the world’s first climate-neutral continent by 2050, this Horizon Europe work programme will continue to allocate at least 35% of its funding to climate objectives. Complementing this, to ensure that Horizon Europe’s actions do not harm environmental policy objectives, a ‘do no harm’ assessment will continue to be carried out. In addition, in line with increased efforts on biodiversity under the second Horizon Europe strategic plan (2025-2027), Horizon Europe aims to dedicate at least 10% of its 2025-2027 budget to biodiversity-related topics.

The parts of this work programme dedicated to the six clusters falling under Pillar II ‘Global Challenges and European Industrial Competitiveness’, together with the research infrastructures, widening participation and strengthening the European Research Area, European Innovation Ecosystems, EU Missions, New European Bauhaus Facility and Horizontal Activities parts, contribute over EUR 4 903 million 7 to climate action, which corresponds to 46.3% of the budget for these parts of the work programme. Furthermore, these parts will contribute EUR 1 661 million to biodiversity, which corresponds to 15.7% of their budget.

Contributions to climate action are made by 16.6% of resources spent under Cluster 1 ‘Health’ (EUR 176 million), 10.0% spent under Cluster 2 ‘Culture, Creativity and Inclusive Society’ (EUR 64 million), 28.6% spent under Cluster 3 ‘Civil Security for Society’ (EUR 96 million), 22.6% spent under Cluster 4 8  ‘Digital, Industry and Space’ (EUR 437 million), 89.7% spent under Cluster 5 ‘Climate, Energy and Transport’ (EUR 1 644 million) and 66.1% spent under Cluster 6 ‘Natural Resources, Agriculture and Environment’ (EUR 778 million). The EU Missions, New European Bauhaus and Horizontal Activities parts, including actions relating to the Clean Industrial Deal, contribute EUR 1 395 million, which corresponds to 68.7%.

Horizon Europe will also continue promoting R&I with the aim of making this decade Europe’s digital decade. This will help empower society, including enterprises, to navigate technology-human interactions responsibly, upholding human rights and ecological limits. Therefore, at least EUR 13 billion from the Horizon Europe budget is to be allocated to developing core digital technologies over the lifetime of the framework programme. Furthermore, in line with the AI Continent Action Plan ’s commitment to accelerating AI development and deployment across strategic sectors, the EU is taking a leading role by funding projects focused on developing safe and ethical AI applications. These efforts promote AI ‘made in Europe’, driving innovation from research labs to the marketplace. An estimated 35.8% of funds allocated under the six clusters, the research infrastructures, widening participation and strengthening the European Research Area, European Innovation Ecosystems, EU Missions, New European Bauhaus Facility and Horizontal Activities parts of the work programme, corresponding to EUR 3 780 million, and 33% of funds across all parts of Horizon Europe, contribute to the digital transition. The overall investment in topics that encourage the development of AI in 2026 and 2027 is estimated at EUR 2 023 million, augmented by projects leveraging AI-based approaches.

Investment in climate action, biodiversity and the digital transition will contribute to achieving the United Nations Sustainable Development Goals. By fostering research and innovation in these areas, Horizon Europe helps to create a more sustainable, digital and resilient Europe for the benefit of all.

What you will find in this work programme

Each part of this work programme, except for this general introduction and the general annexes, is designed around a series of coherent packages of impact-driven destinations, calls for proposals and topics.

Each destination describes the socio-economic challenges to be addressed and the expected impact of the R&I activities. In many cases, destinations correspond directly to an expected impact identified in the second Horizon Europe strategic plan (2025-2027). Together, the destinations set out in this work programme cover the 32 expected impacts identified in this strategic plan.

Each destination comprises one or more topics. Each topic describes the expected outcomes and the scope of the R&I activities to be funded. The expected outcomes are the desired effects of the project in the medium term, such as the uptake, diffusion, use and/or deployment of the project’s results by direct target groups. The scope describes the area of research/innovation that needs to be tackled if the expected outcomes are to be successfully achieved, without prescribing how this should be done. It is therefore left to the creativity and skill of the applicants to design a project that will generate results and substantially contribute to the expected outcomes and impacts.

Each topic also sets out the general conditions, deadlines, budget and any specific conditions that may apply. The topics are grouped under calls for proposals, which is a technical term for a number of topics that open for submission of applications on the same date.

(1)

See Council Decision (EU) 2021/764 .

(2)

Open topics are topics for which the expected outcomes or impacts are clearly defined, but the pathways and methods to achieve them remain open-ended. This flexibility allows for diverse approaches and outputs. Open topics are subject to the same evaluation criteria as the other topics.

(3)

Findable, accessible, interoperable and reusable.

(4)

 Open strategic autonomy’ refers to the term ‘strategic autonomy, while preserving an open economy’, as reflected in the Conclusions of the European Council of 1/2 October 2020 .

(5)

These partnerships are: 2Zero (Towards zero-emission road transport), CCAM (Connected, Cooperative and Automated Driving), and BATT4EU (European Partnership for an Industrial Battery Value Chain).

(6)

 Notably, Outermost Regions as well as Overseas Countries and Territories are particularly encouraged to take part in Pillar II dedicated actions to boost researcher participation, focusing on their R&I expertise in areas such as climate change, energy transition, biodiversity and ecosystems restoration, agriculture and life sciences, marine sciences, metabolic and emerging diseases, earth and space sciences, social sciences and innovation. Since 2021, the nine Outermost Regions have access to the “Widening Participation and Spreading Excellence” instrument, which supports high-quality European funding proposals through free of charge tools like pre-proposal checks. This work programme thereby aligns with the objectives of the future strategy for Outermost Regions, announced in the 2025 State of the European Union address.

(7)

This calculation takes into account only the ‘EU-voted budget’ and does not include contributions by associated countries. The EU-voted budget makes up 89.7% on average, varying between 79% in Cluster 1 and 91.5% in Cluster 2, as a result of earlier effective participation of UK entities in the domains of clusters that shall guide the use of UK provided funds.

(8)

Clusters 4 and 5 also finance the clean industrial deal call under the Horizontal actions.

Top

EN

Annex II

Horizon Europe

Work Programme 2026-2027

2. Marie Skłodowska-Curie Actions

Table of contents

Introduction    

MSCA Doctoral Networks    

Call - MSCA Doctoral Networks 2026    

Conditions for the Call    

HORIZON-MSCA-2026-DN-01-01: MSCA Doctoral Networks 2026    

Call - MSCA Doctoral Networks 2027    

Conditions for the Call    

HORIZON-MSCA-2027-DN-01-01: MSCA Doctoral Networks 2027    

MSCA Postdoctoral Fellowships    

Call - MSCA Postdoctoral Fellowships 2026    

Conditions for the Call    

HORIZON-MSCA-2026-PF-01-01: MSCA Postdoctoral Fellowships 2026    

Call - MSCA Postdoctoral Fellowships 2027    

Conditions for the Call    

HORIZON-MSCA-2027-PF-01-01: MSCA Postdoctoral Fellowships 2027    

MSCA Staff Exchanges    

Call - MSCA Staff Exchanges 2026    

Conditions for the Call    

HORIZON-MSCA-2026-SE-01-01: MSCA Staff Exchanges 2026    

Call - MSCA Staff Exchanges 2027    

Conditions for the Call    

HORIZON-MSCA-2027-SE-01-01: MSCA Staff Exchanges 2027    

MSCA Co-funding of regional, national and international programme    

Call - MSCA COFUND 2026    

Conditions for the Call    

HORIZON-MSCA-2026-COFUND-01-01: MSCA COFUND 2026    

Call - MSCA COFUND 2027    

Conditions for the Call    

HORIZON-MSCA-2027-COFUND-01-01: MSCA COFUND 2027    

Call - MSCA Choose Europe for Science 2027    

Conditions for the Call    

HORIZON-MSCA-2027-COFUND-02-01: MSCA Choose Europe for Science 2027    

MSCA and Citizens    

Call - MSCA and Citizens 2027    

Conditions for the Call    

HORIZON-MSCA-2027-CITIZENS-01-01: MSCA and Citizens 2027    

Other Actions not subject to calls for proposals    

Grants not subject to calls for proposals    

1. MSCA Irish Presidency event 2026    

2. MSCA Lithuanian Presidency event 2027    

3. Support to the Marie Curie Alumni Association    

4. MSCA Special needs Allowances to Horizon 2020 legacy projects    

Procurements    

1. Public Procurement for Events and Outreach    

Other budget implementation instruments    

1. External Expertise    

Budget    

Specific conditions for the Marie Skłodowska-Curie Actions    

DEFINITIONS    

1.    MSCA DOCTORAL NETWORKS    

1.1.    Applicable unit contributions    

1.2.    Admissibility    

1.3.    Eligibility    

1.4.    Award criteria    

1.5.    Procedure    

1.6.    Legal and financial set-up of the Grant Agreements    

2.    MSCA POSTDOCTORAL FELLOWSHIPS    

2.1.    Applicable unit contributions    

2.2.    Admissibility    

2.3.    Eligibility    

2.4.    Award criteria    

2.5.    Procedure    

2.6.    Legal and Financial set-up of the Grant Agreements    

3.    MSCA STAFF EXCHANGES    

3.1.    Applicable unit contributions    

3.2.    Admissibility    

3.3.    Eligibility    

3.4.    Award criteria    

3.5.    Procedure    

3.6.    Legal and financial set-up of the Grant Agreements    

4.    MSCA COFUND    

4.1.    Applicable unit contributions    

4.2.    Admissibility    

4.3.    Eligibility    

4.4.    Award criteria    

4.5.    Procedure    

4.6.    Legal and financial set-up of the Grant Agreements    

5.    MSCA CHOOSE EUROPE FOR SCIENCE    

5.1.    Applicable unit contributions    

5.2.    Admissibility    

5.3.    Eligibility    

5.4.    Award criteria    

5.5.    Procedure    

5.6.    Legal and financial set-up of the Grant Agreements    

Table 1: Country correction coefficients (CCC) for Doctoral Networks and Postdoctoral Fellowships living allowances    

Introduction

The European Union needs a strong, resilient, flexible and creative workforce, with the right combination of skills to match the future needs of the labour market, to innovate and to convert knowledge and ideas into products and services for economic and social benefit. The Covid-19 crisis has highlighted once more the importance of the Union’s reliance on a highly skilled research-based human capital that is able to detect and tackle upcoming challenges, to communicate scientific evidence to policymakers and the public at large, and to work across disciplines.

In this context, and in line with the Union of Skills strategic framework, the Union must reinforce its efforts to encourage more young women and men to make a career in research, promote its attractiveness for top talents from around the world, retain its own researchers and reintegrate those working elsewhere. The Marie Skłodowska-Curie Actions (MSCA) are the main instrument at Union-level to do so. Since their launch in 1996, they have become the Union’s reference programme for doctoral education and postdoctoral training. Between 2014 and 2020, in the context of Horizon 2020, the MSCA have supported 65 000 researchers in Europe and beyond, both doctoral candidates and more experienced researchers, and have funded over 1 000 excellent international doctoral networks.

The MSCA strongly contribute to excellent research, boosting jobs, growth and investment by equipping researchers with new knowledge and skills, including transferable ones 1  and providing them with an international as well as inter-sectoral exposure (including through academia-business collaboration), to fill the top positions of tomorrow.

The MSCA do not only have a positive impact on individual researchers, they also contribute to the development of excellent doctoral programmes, postdoctoral training programmes and collaborative research projects. They have a structuring impact on higher education institutions and other entities way beyond academia by widely spreading excellence and setting standards for high-quality researcher education and training, not only across the European Research Area (ERA), but also worldwide. Positive structuring effects on organisations include:

1.increasing the quality of researchers’ training and supervision offered;

2.strengthening research capacity (e.g. ability to attract funding);

3.improving human resources practices and procedures, and providing fairer and more attractive working conditions for researchers, including through career guidance and development;

4.building new and sustainable international and inter-sectoral partnerships and networks; better transfer of knowledge between sectors and disciplines, enhancing their global reputation and visibility.

Main principles applying to the MSCA

Excellence

The MSCA focus on excellence in various aspects: excellence does not only apply to the individual fellows supported or the collaborations fostered and knowledge transferred, but also to the R&I methodologies applied, the research conducted as well as the training, supervision and career guidance provided. Long-term investment in people pays off, as indicated inter alia by the number of Nobel Prize winners who have been either former MSCA fellows or supervisors.

Mobility

The MSCA are based on the principle of physical mobility: researchers who receive funding have to move from one country to another to acquire new knowledge, skills and competences, and develop their research career. Researchers are also strongly encouraged to move between sectors and disciplines.

While virtual mobility does not have the same multifaceted impact on the development of individuals and sustainable cooperation among organisations as physical mobility, it can however complement it, facilitate long-distance collaboration and be an effective means to faster achieving research and training objectives. In this regard, all MSCA proposals are encouraged to explore opportunities offered by e-infrastructures and related services, in particular those provided through GEANT 2 , the pan-European research and education network.

Bottom-up and open to the world

The MSCA are open to all domains of research and innovation, chosen freely by the applicants in a fully bottom-up manner, addressed under the Treaty on the Functioning of the European Union. In addition, Postdoctoral Fellowships can also address domains covered by the Treaty establishing the European Atomic Energy Community (Euratom Research and Training Programme). All MSCA will complement top-down collaborative research activities, notably contributing to the EU Missions.

The MSCA have also a strong international dimension: international cooperation is particularly encouraged as it allows institutions to set-up strategic collaborations worldwide, attracts foreign talents to Europe and provides European researchers with access to unique expertise, facilities, testing environments or data available only outside Europe. At the same time, it is essential to ensure the protection of the European Union from undesired technology leakage or transfers that impact security, problematic dependencies and foreign interference, by implementing targeted security safeguards in line with the 2023 European Economic Security Strategy and the 2024 Council Recommendation on enhancing research security.

Recruitment, working/employment conditions and inclusiveness

The principles of the European Charter for Researchers ( Charter ) promoting open, merit-based and transparent recruitment and attractive working and employment conditions are a cornerstone of the MSCA and all funded host organisations must put effort into applying them. The MSCA pay particular attention to equal opportunities and inclusiveness. In line with the Charter, all MSCA-funded projects are encouraged to embrace diversity and take measures to facilitate mobility and counter-act gender and disability-related barriers to it.

MSCA projects are also encouraged to facilitate access by researchers at risk 3 , through tailored support and career services, including job search assistance in the researcher’s new geographical area.

Supervision

The MSCA promote effective supervision, which contribute to creating a supportive environment for the researchers to conduct their work. In line with the principles set out in the Charter, MSCA beneficiaries must ensure adequately supervision or mentoring and appropriate career guidance. Supervision is one of the crucial elements of successful research. Guiding, supporting, directing, advising and mentoring are key factors for a researcher to pursue their career path. In this context, all MSCA-funded projects are encouraged to follow the recommendations outlined in the Guidelines for MSCA supervision 4 .

Open Science and Responsible Research and Innovation

The MSCA endorse Open Science and Responsible Research and Innovation (RRI) through engaging society at large, integrating the gender and ethical dimensions, promoting Open Science practices through targeted training activities, ensuring open access to research outcomes, including FAIR 5 data handling, supporting methods that enhance research reproducibility, encouraging formal and informal science education and feeding back research results into teaching and education.

The European Commission has also signed the Agreement on Reforming Research Assessment 6 , which establishes a common direction for research assessment reforms, while respecting organisations’ autonomy.

European Green Deal

The MSCA support bottom-up and frontier/applied research contributing directly to the European Commission’s commitment to tackling climate and environmental-related challenges. Under Horizon Europe, the MSCA will significantly contribute to promote sustainable research in line with the European Green Deal, the United Nation’s 2030 Agenda and the Sustainable Development Goals. All MSCA-funded projects are encouraged to address the principles of the MSCA Green Charter 7 and implement measures to minimise the environmental footprint of their activities.

Synergies

The MSCA promote the creation of strong links with the cohesion policy funds 8 and the Recovery and Resilience Facility (RRF) 9 , notably by creating synergies through its COFUND action and enabling complementarities via awarding a Seal of Excellence 10 certificate to proposals submitted to mono-beneficiary MSCA calls. The Seal is awarded to proposals that exceed all the evaluation thresholds set out in this work programme but cannot be funded due to lack of budget. The MSCA also encourage complementarities with other parts of Horizon Europe, such as the European Innovation Council 11 and European Institute of Innovation and Technology (EIT) 12 , and synergies with other Union programmes, notably Erasmus+ 13 , including its European Universities Initiative.

MSCA intervention areas

There are five main MSCA intervention areas as set out in the Council Decision establishing the specific programme implementing Horizon Europe (Annex 1, page 11-13). All individual Marie Skłodowska-Curie Actions contribute to these intervention areas to one extent or the other:

1.Nurturing Excellence through Mobility of Researchers across Borders, Sectors and Disciplines;

2.Fostering new Skills through Excellent Training of Researchers;

3.Strengthening Human Capital and Skills Development across the European Research Area;

4.Improving and Facilitating Synergies;

5.Promoting Public Outreach.

The following Actions within the MSCA are implementing these intervention areas:

Action

Main Objective

MSCA Doctoral Networks

The MSCA Doctoral Networks aim to train creative, entrepreneurial, innovative and resilient doctoral candidates, able to face current and future challenges and to convert knowledge and ideas into products and services for economic and social benefit. The MSCA Doctoral Networks will raise the attractiveness and excellence of doctoral training in Europe. They will equip researchers with the right combination of research-related and transferable competences and provide them with enhanced career perspectives in both the academic 14 and non-academic sectors through international, inter-sectoral and interdisciplinary mobility combined with an innovation-oriented mind-set.

MSCA Postdoctoral Fellowships

The goal of MSCA Postdoctoral Fellowships is to enhance the creative and innovative potential of researchers holding a PhD, wishing to acquire new skills through advanced training, international, inter-sectoral and interdisciplinary mobility. MSCA Postdoctoral Fellowships are open to excellent researchers of any nationality, including researchers wishing to reintegrate in Europe, researchers who are displaced by conflict as well as researchers with high potential aiming for a career restart in research. The scheme also encourages researchers to work on research and innovation projects in the non-academic sector.

MSCA Staff Exchanges

MSCA Staff Exchanges promote innovative international, inter-sectoral and interdisciplinary collaboration in research and innovation through exchanging staff and sharing knowledge and ideas at all stages of the innovation chain. The scheme fosters a shared culture of research and innovation that welcomes and rewards creativity and entrepreneurship and helps turn ideas into innovative products, services or processes. It is open to research, technical, administrative and managerial staff.

MSCA COFUND

MSCA COFUND co-finances new or existing doctoral programmes and postdoctoral fellowship schemes at national, regional or international level with the aim to spread the best practices of the MSCA including international, inter-sectoral and interdisciplinary research training, as well as international and cross-sectoral mobility of researchers at all stages of their career. MSCA Choose Europe for Science co-funded programmes additionally aim to address brain drain and precarity of researchers' careers in order to make Europe more attractive to the most promising young talents.

MSCA and Citizens

MSCA and Citizens, through the European Researchers’ Night, aims to bring research and researchers closer to the public at large, to increase awareness of research and innovation activities and to boost public recognition of science and research education. It will also show the role of the researcher for the society and economy, as well as the impact of researchers’ work on citizens’ daily lives and aim at raising young people’s interest for research and scientific careers.

MSCA Doctoral Networks

The MSCA Doctoral Networks aim to train creative, entrepreneurial, innovative and resilient doctoral candidates, able to face current and future challenges and to convert knowledge and ideas into products and services for economic and social benefit.

The MSCA Doctoral Networks will raise the attractiveness and excellence of doctoral training in Europe. They will equip researchers with the right combination of research-related and transferable competences and provide them with enhanced career perspectives in both the academic and non-academic sectors through international, inter-sectoral and interdisciplinary mobility combined with an innovation-oriented mind-set.

Expected impact

Proposals under this Action should contribute to the following expected impacts:

1.Strengthen Europe's human capital base in R&I by training highly-skilled doctoral candidates;

2.Improve the attractiveness of researchers’ careers notably through better working and employment conditions of doctoral candidates in Europe;

3.Enhance talent and knowledge circulation across the R&I landscape, through international, inter-sectoral and interdisciplinary mobility;

4.Increase Europe's attractiveness as a leading research destination;

5.Enhance the quality of R&I contributing to Europe's sustainable competitiveness;

6.Establish sustainable collaboration between academic and non-academic organisations;

7.Foster the culture of open science, innovation and entrepreneurship.

The following call(s) in this work programme contribute to this Action:

Call

Budgets (EUR million)

Deadline(s)

2026

2027

HORIZON-MSCA-2026-DN-01

593.03

24 Nov 2026

HORIZON-MSCA-2027-DN-01

574.62

23 Nov 2027

Overall indicative budget

593.03

574.62

Call - MSCA Doctoral Networks 2026

HORIZON-MSCA-2026-DN-01

Conditions for the Call

Indicative budget(s) 15

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million)

Indicative number of projects expected to be funded

2026

Opening: 28 May 2026

Deadline(s): 24 Nov 2026

HORIZON-MSCA-2026-DN-01-01

TMA Doctoral Networks

593.03

Not relevant

HORIZON-MSCA-2026-DN-01-01

TMA Doctoral Networks - Industrial Doctorates

593.03

Not relevant

HORIZON-MSCA-2026-DN-01-01

TMA Doctoral Networks - Joint Doctorates

593.03

Not relevant

Overall indicative budget

593.03

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A. See exceptions and specific conditions at the end of this work programme part.

Eligibility conditions

The general conditions are described in General Annex B. See exceptions and specific conditions at the end of this work programme part

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

For application of the general award criteria, including weighting and thresholds, see the specific conditions at the end of this Work Programme part.

Documents

The documents are described in General Annex E.

Procedure

The general procedure is described in General Annex F. See exceptions and specific conditions at the end of this work programme part

Expected EU contribution per project

The expected EU contribution depends on the number of person-months requested. For the applicable unit contributions, see specific conditions for MSCA at the end of this Work Programme part.

Legal and financial set-up of the Grant Agreements

The general conditions are described in General Annex G. See exceptions and specific conditions at the end of this Work Programme part.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2026-DN-01-01: MSCA Doctoral Networks 2026

Expected Outcome: Project results are expected to contribute to the following outcomes:

For supported doctoral candidates

1.New research and transferable skills and competences, leading to improved employability and career prospects within and outside academia;

2.New knowledge allowing the conversion of ideas into products and services, where relevant;

3.Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.

For participating organisations

1.Improved quality, relevance and sustainability of doctoral training programmes and supervision arrangements;

2.Enhanced cooperation and transfer of knowledge between sectors and disciplines;

3.Increased integration of training and research activities between participating organisations;

4.Boosted R&I capacity;

5.Increased internationalisation and attractiveness;

6.Regular feedback of research results into teaching and education at participating organisations.

Scope: MSCA Doctoral Networks will implement doctoral programmes, by partnerships of universities, research institutions and research infrastructures, businesses including SMEs, and other socio-economic actors from different countries across Europe and beyond. MSCA Doctoral Networks are indeed open to the participation of organisations from third countries, in view of fostering strategic international partnerships for the training and exchange of researchers.

These doctoral programmes will respond to well-identified needs in various R&I areas, expose the researchers to the academic and non-academic sectors, and offer training in research-related, as well as transferable skills and competences relevant for innovation and long-term employability (e.g. entrepreneurship, commercialisation of results, Intellectual Property Rights, communication). Proposals for doctoral networks can reflect existing or planned research partnerships among the participating organisations.

The selection procedure for doctoral candidates must be open, transparent and merit-based, in line with the European Charter for Researchers. The vacancy notice (to be widely advertised internationally, including on the EURAXESS 16 website) must mention if the published rates include all employer and employee's taxes and contributions. If possible, the gross salary (net salary + employee’s taxes and contributions) should be published.

MSCA Doctoral Networks are encouraged to lead to Industrial or Joint Doctorates.

Industrial Doctorates

Through Industrial Doctorates, doctoral candidates will step outside academia and develop skills in industry and business by being jointly supervised by academic and non-academic organisations, both of which can be established in the same EU Member State or Horizon Europe Associated Country.

Joint Doctorates

Joint Doctorates represent a highly integrated type of international, inter-sectoral and multi/interdisciplinary collaboration in doctoral training. They lead to the delivery of joint, double or multiple doctoral degrees 17 recognised in at least one EU Member State or Horizon Europe Associated Country.

Supervisory Board

Each MSCA Doctoral Network should have a clearly identified supervisory board co-ordinating network-wide training, research and in particular supervision activities in line with the Guidelines for MSCA supervision, while establishing continuous communication and exchange of best practice among the participating organisations to maximise the benefits of the partnership.

Training activities

MSCA Doctoral Networks should exploit complementarities between participating organisations and foster sharing of knowledge and networking activities for example through the organisation of workshops and conferences. Proposed training activities should respond to well identified needs in various R&I areas, with appropriate references to inter- and multidisciplinary fields and follow the EU Principles for Innovative Doctoral Training 18 . They should be primarily focused on developing new scientific knowledge through original research on personalised projects.

Inter-sectoral secondments of researchers to other participating organisations, including in third countries, are encouraged when relevant, feasible and beneficial for the researchers and in line with the project objectives. This will increase the employability of the researchers outside academia.

Doctoral Networks should develop substantial training modules, addressing key transferable skills and competences common to all fields, including digital ones (e.g. generative AI) and foster the culture of Open Science, knowledge valorisation 19 , and when applicable innovation and entrepreneurship as well as good scientific conduct such as research integrity. In particular, Doctoral Networks should adequately prepare doctoral candidates to pursue a career in research and for increased research collaboration and information-sharing made possible by new (digital) technologies (e.g. collaborative tools, opening access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science, etc.).

Supervision

Particular attention is paid to the quality of supervision and mentoring arrangements as well as career guidance. Joint supervision of the researchers is mandatory for Industrial and Joint Doctorates.

Career Development Plan

A Career Development Plan must be established jointly by the supervisor and each recruited doctoral candidate. In case of joint supervision, such a plan should be established involving all supervisors. In addition to research objectives, this plan comprises the researcher's training and career needs, including training on transferable skills, teaching, planning for publications and participation in conferences and events aiming at opening science and research to citizens. The plan, established at the beginning of the recruitment, should be revised (and updated where needed) within 18 months.

RAISE Doctoral Networks

The RAISE Doctoral Networks, implemented through Work Programme Annex 14, Horizontal Activities, provide specific support to networks with primary focus on the use of AI in science.

Call - MSCA Doctoral Networks 2027

HORIZON-MSCA-2027-DN-01

Conditions for the Call

Indicative budget(s) 20

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million)

Indicative number of projects expected to be funded

2027

Opening: 26 May 2027

Deadline(s): 23 Nov 2027

HORIZON-MSCA-2027-DN-01-01

TMA Doctoral Networks

574.62

Not relevant

HORIZON-MSCA-2027-DN-01-01

TMA Doctoral Networks - Industrial Doctorates

574.62

Not relevant

HORIZON-MSCA-2027-DN-01-01

TMA Doctoral Networks - Joint Doctorates

574.62

Not relevant

Overall indicative budget

574.62

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A. See exceptions and specific conditions at the end of this work programme part.

Eligibility conditions

The general conditions are described in General Annex B. See exceptions and specific conditions at the end of this work programme part

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

For application of the general award criteria, including weighting and thresholds, see the specific conditions at the end of this Work Programme part.

Documents

The documents are described in General Annex E.

Procedure

The general procedure is described in General Annex F. See exceptions and specific conditions at the end of this work programme part

Expected EU contribution per project

The expected EU contribution depends on the number of person-months requested. For the applicable unit contributions, see specific conditions for MSCA at the end of this Work Programme part.

Legal and financial set-up of the Grant Agreements

The general conditions are described in General Annex G. See exceptions and specific conditions at the end of this Work Programme part.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2027-DN-01-01: MSCA Doctoral Networks 2027

Expected Outcome: Project results are expected to contribute to the following outcomes:

For supported doctoral candidates

1.New research and transferable skills and competences, leading to improved employability and career prospects within and outside academia;

2.New knowledge allowing the conversion of ideas into products and services, where relevant;

3.Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.

For participating organisations

1.Improved quality, relevance and sustainability of doctoral training programmes and supervision arrangements;

2.Enhanced cooperation and transfer of knowledge between sectors and disciplines;

3.Increased integration of training and research activities between participating organisations;

4.Boosted R&I capacity;

5.Increased internationalisation and attractiveness;

6.Regular feedback of research results into teaching and education at participating organisations.

Scope: MSCA Doctoral Networks will implement doctoral programmes, by partnerships of universities, research institutions and research infrastructures, businesses including SMEs, and other socio-economic actors from different countries across Europe and beyond. MSCA Doctoral Networks are indeed open to the participation of organisations from third countries, in view of fostering strategic international partnerships for the training and exchange of researchers.

These doctoral programmes will respond to well-identified needs in various R&I areas, expose the researchers to the academic and non-academic sectors, and offer training in research-related, as well as transferable skills and competences relevant for innovation and long-term employability (e.g. entrepreneurship, commercialisation of results, Intellectual Property Rights, communication). Proposals for doctoral networks can reflect existing or planned research partnerships among the participating organisations.

The selection procedure for doctoral candidates must be open, transparent and merit-based, in line with the European Charter for Researchers. The vacancy notice (to be widely advertised internationally, including on the EURAXESS 21 website) must mention if the published rates include all employer and employee's taxes and contributions. If possible, the gross salary (net salary + employee’s taxes and contributions) should be published.

MSCA Doctoral Networks are encouraged to lead to Industrial or Joint Doctorates.

Industrial Doctorates

Through Industrial Doctorates, doctoral candidates will step outside academia and develop skills in industry and business by being jointly supervised by academic and non-academic organisations, both of which can be established in the same EU Member State or Horizon Europe Associated Country.

Joint Doctorates

Joint Doctorates represent a highly integrated type of international, inter-sectoral and multi/interdisciplinary collaboration in doctoral training. They lead to the delivery of joint, double or multiple doctoral degrees 22 recognised in at least one EU Member State or Horizon Europe Associated Country.

Supervisory Board

Each MSCA Doctoral Network should have a clearly identified supervisory board co-ordinating network-wide training, research and in particular supervision activities in line with the Guidelines for MSCA supervision, while establishing continuous communication and exchange of best practice among the participating organisations to maximise the benefits of the partnership.

Training activities

MSCA Doctoral Networks should exploit complementarities between participating organisations and foster sharing of knowledge and networking activities for example through the organisation of workshops and conferences. Proposed training activities should respond to well identified needs in various R&I areas, with appropriate references to inter- and multidisciplinary fields and follow the EU Principles for Innovative Doctoral Training 23 . They should be primarily focused on developing new scientific knowledge through original research on personalised projects.

Inter-sectoral secondments of researchers to other participating organisations, including in third countries, are encouraged when relevant, feasible and beneficial for the researchers and in line with the project objectives. This will increase the employability of the researchers outside academia.

Doctoral Networks should develop substantial training modules, addressing key transferable skills and competences common to all fields, including digital ones (e.g. generative AI) and foster the culture of Open Science, knowledge valorisation 24 , and when applicable innovation and entrepreneurship as well as good scientific conduct such as research integrity. In particular, Doctoral Networks should adequately prepare doctoral candidates to pursue a career in research and for increased research collaboration and information-sharing made possible by new (digital) technologies (e.g. collaborative tools, opening access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science, etc.).

Supervision

Particular attention is paid to the quality of supervision and mentoring arrangements as well as career guidance. Joint supervision of the researchers is mandatory for Industrial and Joint Doctorates.

Career Development Plan

A Career Development Plan must be established jointly by the supervisor and each recruited doctoral candidate. In case of joint supervision, such a plan should be established involving all supervisors. In addition to research objectives, this plan comprises the researcher's training and career needs, including training on transferable skills, teaching, planning for publications and participation in conferences and events aiming at opening science and research to citizens. The plan, established at the beginning of the recruitment, should be revised (and updated where needed) within 18 months.

MSCA Postdoctoral Fellowships

The goal of MSCA Postdoctoral Fellowships is to enhance the creative and innovative potential of researchers holding a PhD and who wish to acquire new skills through advanced training, international, inter-sectoral and interdisciplinary mobility. MSCA Postdoctoral Fellowships will be open to excellent researchers of any nationality. The scheme also encourages researchers to work on research and innovation projects in the non-academic sector and is open to researchers wishing to reintegrate in Europe, to those who are displaced by conflict, as well as to researchers with high potential who are seeking to restart their careers in research.

Through the implementation of an original and personalised research project, MSCA Postdoctoral Fellowships aim to foster excellence through training and mobility and to equip researchers with new skills and competences in order to identify solutions to current and future challenges. Postdoctoral researchers are encouraged to engage with society at large to make the results of their research visible to citizens and to involve citizens, civil society and end-users in co-creation of research content when relevant.

Expected impact

Proposals under this Action should contribute to the following expected impacts:

1.Enhance the creative and innovative potential of researchers holding a PhD and wishing to diversify their individual competences and skills through advanced training, international, interdisciplinary and inter-sectoral mobility while implementing excellent research projects across all sectors of research;

2.Strengthen Europe's human capital base in R&I with better trained, innovative and entrepreneurial researchers;

3.Enhance the quality of R&I contributing to Europe's competitiveness and growth;

4.Contribute to Europe's attractiveness as a leading destination for R&I and for good working conditions of researchers;

5.Facilitate knowledge transfer and brain circulation across the ERA;

6.Foster the culture of open science, innovation and entrepreneurship.

The following call(s) in this work programme contribute to this Action:

Call

Budgets (EUR million)

Deadline(s)

2026

2027

HORIZON-MSCA-2026-PF-01

399.05

09 Sep 2026

HORIZON-MSCA-2027-PF-01

388.57

08 Sep 2027

Overall indicative budget

399.05

388.57

Call - MSCA Postdoctoral Fellowships 2026

HORIZON-MSCA-2026-PF-01

Conditions for the Call

Indicative budget(s) 25

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million)

Indicative number of projects expected to be funded

2026

Opening: 09 Apr 2026

Deadline(s): 09 Sep 2026

HORIZON-MSCA-2026-PF-01-01

TMA Postdoctoral Fellowships - European Fellowships

339.19

Not relevant

HORIZON-MSCA-2026-PF-01-01

TMA Postdoctoral Fellowships - Global Fellowships

59.86

Not relevant

Overall indicative budget

399.05

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A. See exceptions and specific conditions at the end of this work programme part.

Eligibility conditions

The general conditions are described in General Annex B. See exceptions and specific conditions at the end of this work programme part

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

For application of the general award criteria, including weighting and thresholds, see the specific conditions at the end of this Work Programme part.

Documents

The documents are described in General Annex E.

Procedure

The general procedure is described in General Annex F. See exceptions and specific conditions at the end of this work programme part

Expected EU contribution per project

The expected EU contribution depends on the number of person-months requested. For the applicable unit contributions, see specific conditions for MSCA at the end of this Work Programme part.

Legal and financial set-up of the Grant Agreements

The general conditions are described in General Annex G. See exceptions and specific conditions at the end of this Work Programme part.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2026-PF-01-01: MSCA Postdoctoral Fellowships 2026

Specific conditions

Indicative budget

The total indicative budget for the topic is EUR 339.19 million.

Type of Action

TMA Postdoctoral Fellowships - European Fellowships

Indicative budget

The total indicative budget for the topic is EUR 59.86 million.

Type of Action

TMA Postdoctoral Fellowships - Global Fellowships

Expected Outcome: Project results are expected to contribute to the following outcomes:

For supported postdoctoral fellows

1.Increased set of research and transferable skills and competences, leading to improved employability and career prospects of MSCA postdoctoral fellows within academia and beyond;

2.New mind-sets and approaches to R&I work forged through international, inter-sectoral and interdisciplinary experience;

3.Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.

For participating organisations

1.Increased alignment of working conditions for researchers in accordance with the principles set out in the European Charter for Researchers;

2.Enhanced quality and sustainability of research training and supervision;

3.Increased global attractiveness, visibility and reputation of the participating organisation(s);

4.Stronger R&I capacity and output among participating organisations; better transfer of knowledge;

5.Regular feedback of research results into teaching and education at participating organisations.

Scope: Fellowships will be provided to excellent researchers undertaking international mobility. Applications will be made jointly by the researcher and a beneficiary in the academic or non-academic sector.

Postdoctoral Fellowships either can take place in Europe (i.e. in an EU Member State or a Horizon Europe Associated Country) or in a Third Country not associated to Horizon Europe:

1.European Postdoctoral Fellowships are open to researchers of any nationality who wish to engage in R&I projects by either coming to Europe from any country in the world or moving within Europe. The standard duration of these fellowships must be between 12 and 24 months.

2.Global Postdoctoral Fellowships are open to European nationals or long-term residents 26 who wish to engage in R&I projects with organisations outside EU Member States and Horizon Europe Associated Countries. These fellowships require an outgoing phase of minimum 12 and maximum 24 months in a non-associated Third Country, and a mandatory 12-month return phase to a host organisation based in an EU Member State or a Horizon Europe Associated Country.

Specific eligibility conditions apply to MSCA Postdoctoral Fellowships in the research areas covered by the Euratom Research and Training Programme 27 .

Secondments

Researchers receiving a Postdoctoral Fellowship may opt to include a secondment phase, within the overall duration of their fellowship in any country worldwide. The secondment phase can be a single period or be divided into shorter mobility periods.

For European Postdoctoral Fellowships, secondments cannot exceed half of the requested duration of the action (excluding from the duration of the action any additional period for a non-academic placement) and should be in line with the project objectives, adding significant value and impact to the fellowship.

For Global Postdoctoral Fellowships, optional secondments are permitted for up to half of the outgoing phase. A maximum of three months of such secondments can be spent at the start of the project at the beneficiary (or associated partners linked to the beneficiary), allowing the researcher to spend time there before going to the associated partner in the Third Country. This period of maximum three months will be considered as part of the outgoing phase.

Secondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.

Placements in the non-academic sector

Postdoctoral Fellowships can provide an additional period of up to six months to support researchers opting for a placement at the end of the project to work on R&I projects in an organisation from the non-academic sector established in an EU Member State or Horizon Europe Associated Country 28 . While this possibility is also available to fellows recruited in the non-academic sector, such a placement must be implemented at a different non-academic host organisation established in an EU Member State or Horizon Europe Associated Country 29 . The request for such a non-academic placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.

If the placement does not meet the requirements (taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. This might affect the final score.

Training activities

The training activities implemented under the Postdoctoral Fellowships should integrate key transferable skills and competences common to all fields, including digital ones (e.g. generative AI), and foster the culture of Open Science, knowledge valorisation 30 , and when applicable innovation and entrepreneurship, as well as good scientific conduct such as research integrity. In particular, the Postdoctoral Fellowships should empower fellows to pursue a career in research and adequately prepare them for increased research collaboration and information-sharing made possible by new (digital) technologies (e.g. collaborative tools, opening access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science, etc.).

Career Development Plan

In order to equip MSCA postdoctoral fellows with skills that enhance and expand their career opportunities inside and outside academia, a Career Development Plan should be established jointly by the supervisor(s) and the researcher. In addition to research objectives, this plan should comprise the researcher's training and career needs, including training on transferable skills, teaching, planning for publications and participation in conferences and events aiming at opening science and research to citizens. The Plan will have to be submitted as a project deliverable at the beginning of the action and can be updated when needed.

Euratom

Aiming to enhance nuclear expertise and excellence as well as synergies between Programmes, organisations active in nuclear research established in one of EU Member States or countries associated to the Euratom Research and Training programme, are eligible to participate 31 . MSCA Postdoctoral Fellowships in this area of research will be supported by the Euratom Research and Training Programme through an indicative annual financial contribution of EUR 1 million to the MSCA Postdoctoral Fellowships call 32 .

ERA Fellowships

The ERA Fellowships implemented through Work Programme Annex 11, Widening Participation and Strengthening the European Research Area, provide specific support to researchers to undertake their fellowship in a widening country 33 . This will help spread excellence and contribute to fostering balanced brain circulation in widening countries.

Call - MSCA Postdoctoral Fellowships 2027

HORIZON-MSCA-2027-PF-01

Conditions for the Call

Indicative budget(s) 34

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million)

Indicative number of projects expected to be funded

2027

Opening: 07 Apr 2027

Deadline(s): 08 Sep 2027

HORIZON-MSCA-2027-PF-01-01

TMA Postdoctoral Fellowships - European Fellowships

330.28

Not relevant

HORIZON-MSCA-2027-PF-01-01

TMA Postdoctoral Fellowships - Global Fellowships

58.29

Not relevant

Overall indicative budget

388.57

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A. See exceptions and specific conditions at the end of this work programme part.

Eligibility conditions

The general conditions are described in General Annex B. See exceptions and specific conditions at the end of this work programme part

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

For application of the general award criteria, including weighting and thresholds, see the specific conditions at the end of this Work Programme part.

Documents

The documents are described in General Annex E.

Procedure

The general procedure is described in General Annex F. See exceptions and specific conditions at the end of this work programme part

Expected EU contribution per project

The expected EU contribution depends on the number of person-months requested. For the applicable unit contributions, see specific conditions for MSCA at the end of this Work Programme part.

Legal and financial set-up of the Grant Agreements

The general conditions are described in General Annex G. See exceptions and specific conditions at the end of this Work Programme part.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2027-PF-01-01: MSCA Postdoctoral Fellowships 2027

Specific conditions

Indicative budget

The total indicative budget for the topic is EUR 330.28 million.

Type of Action

TMA Postdoctoral Fellowships - European Fellowships

Indicative budget

The total indicative budget for the topic is EUR 58.29 million.

Type of Action

TMA Postdoctoral Fellowships - Global Fellowships

Expected Outcome: Project results are expected to contribute to the following outcomes:

For supported postdoctoral fellows

1.Increased set of research and transferable skills and competences, leading to improved employability and career prospects of MSCA postdoctoral fellows within academia and beyond;

2.New mind-sets and approaches to R&I work forged through international, inter-sectoral and interdisciplinary experience;

3.Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.

For participating organisations

1.Increased alignment of working conditions for researchers in accordance with the principles set out in the European Charter for Researchers;

2.Enhanced quality and sustainability of research training and supervision;

3.Increased global attractiveness, visibility and reputation of the participating organisation(s);

4.Stronger R&I capacity and output among participating organisations; better transfer of knowledge;

5.Regular feedback of research results into teaching and education at participating organisations.

Scope: Fellowships will be provided to excellent researchers undertaking international mobility. Applications will be made jointly by the researcher and a beneficiary in the academic or non-academic sector.

Postdoctoral Fellowships either can take place in Europe (i.e. in an EU Member State or a Horizon Europe Associated Country) or in a Third Country not associated to Horizon Europe:

1.European Postdoctoral Fellowships are open to researchers of any nationality who wish to engage in R&I projects by either coming to Europe from any country in the world or moving within Europe. The standard duration of these fellowships must be between 12 and 24 months.

2.Global Postdoctoral Fellowships are open to European nationals or long-term residents 35 who wish to engage in R&I projects with organisations outside EU Member States and Horizon Europe Associated Countries. These fellowships require an outgoing phase of minimum 12 and maximum 24 months in a non-associated Third Country, and a mandatory 12-month return phase to a host organisation based in an EU Member State or a Horizon Europe Associated Country.

Specific eligibility conditions apply to MSCA Postdoctoral Fellowships in the research areas covered by the Euratom Research and Training Programme 36 .

Secondments

Researchers receiving a Postdoctoral Fellowship may opt to include a secondment phase, within the overall duration of their fellowship in any country worldwide. The secondment phase can be a single period or be divided into shorter mobility periods.

For European Postdoctoral Fellowships, secondments cannot exceed half of the requested duration of the action (excluding from the duration of the action any additional period for a non-academic placement) and should be in line with the project objectives, adding significant value and impact to the fellowship.

For Global Postdoctoral Fellowships, optional secondments are permitted for up to half of the outgoing phase. A maximum of three months of such secondments can be spent at the start of the project at the beneficiary (or associated partners linked to the beneficiary), allowing the researcher to spend time there before going to the associated partner in the Third Country. This period of maximum three months will be considered as part of the outgoing phase.

Secondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.

Placements in the non-academic sector

Postdoctoral Fellowships can provide an additional period of up to six months to support researchers opting for a placement at the end of the project to work on R&I projects in an organisation from the non-academic sector established in an EU Member State or Horizon Europe Associated Country 37 . While this possibility is also available to fellows recruited in the non-academic sector, such a placement must be implemented at a different non-academic host organisation established in an EU Member State or Horizon Europe Associated Country 38 . The request for such a non-academic placement must be an integral part of the proposal, explaining the added-value for the project and for the career development of the researcher, and will be subject to evaluation. This incentive aims at promoting career moves between sectors and organisations and thereby stimulate innovation and knowledge transfer while expanding career opportunities for researchers.

If the placement does not meet the requirements (taking place in an academic organisation or in a Third Country), the proposal will be evaluated without taking into account the placement. This might affect the final score.

Training activities

The training activities implemented under the Postdoctoral Fellowships should integrate key transferable skills and competences common to all fields, including digital ones (e.g. generative AI), and foster the culture of Open Science, knowledge valorisation 39 , and when applicable innovation and entrepreneurship, as well as good scientific conduct such as research integrity. In particular, the Postdoctoral Fellowships should empower fellows to pursue a career in research and adequately prepare them for increased research collaboration and information-sharing made possible by new (digital) technologies (e.g. collaborative tools, opening access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science, etc.).

Career Development Plan

In order to equip MSCA postdoctoral fellows with skills that enhance and expand their career opportunities inside and outside academia, a Career Development Plan should be established jointly by the supervisor(s) and the researcher. In addition to research objectives, this plan should comprise the researcher's training and career needs, including training on transferable skills, teaching, planning for publications and participation in conferences and events aiming at opening science and research to citizens. The Plan will have to be submitted as a project deliverable at the beginning of the action and can be updated when needed.

Euratom

Aiming to enhance nuclear expertise and excellence as well as synergies between Programmes, organisations active in nuclear research established in one of EU Member States or countries associated to the Euratom Research and Training programme, are eligible to participate 40 . MSCA Postdoctoral Fellowships in this area of research will be supported by the Euratom Research and Training Programme through an indicative annual financial contribution of EUR 1 million to the MSCA Postdoctoral Fellowships call 41 .

ERA Fellowships

The ERA Fellowships implemented through Work Programme Annex 11, Widening Participation and Strengthening the European Research Area, provide specific support to researchers to undertake their fellowship in a widening country 42 . This will help spread excellence and contribute to fostering balanced brain circulation in widening countries.

MSCA Staff Exchanges

MSCA Staff Exchanges promote innovative international, inter-sectoral and interdisciplinary collaboration in research and innovation through exchanging staff and sharing knowledge and ideas at all stages of the innovation chain. The scheme fosters a shared culture of research and innovation that welcomes and rewards creativity and entrepreneurship and helps turn ideas into innovative products, services or processes. It is open to research, technical, administrative and managerial staff supporting R&I activities.

Expected impact

Proposals under this Action should contribute to the following expected impacts:

1.Increase international, inter-sectoral and interdisciplinary mobility of research staff within Europe and beyond through collaborative research networks and activities;

2.Strengthen the R&I human capital base in Europe and beyond;

3.Increase Europe's attractiveness as a leading destination for R&I;

4.Contribute to Europe's competitiveness and growth through high-quality R&I;

5.Foster the culture of open science, innovation and entrepreneurship.

The following call(s) in this work programme contribute to this Action:

Call

Budgets (EUR million)

Deadline(s)

2026

2027

HORIZON-MSCA-2026-SE-01

97.92

16 Apr 2026

HORIZON-MSCA-2027-SE-01

95.04

15 Apr 2027

Overall indicative budget

97.92

95.04

Call - MSCA Staff Exchanges 2026

HORIZON-MSCA-2026-SE-01

Conditions for the Call

Indicative budget(s) 43

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million)

Indicative number of projects expected to be funded

2026

Opening: 16 Dec 2025

Deadline(s): 16 Apr 2026

HORIZON-MSCA-2026-SE-01-01

TMA Staff Exchanges

97.92

Not relevant

Overall indicative budget

97.92

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A. See exceptions and specific conditions at the end of this work programme part.

Eligibility conditions

The general conditions are described in General Annex B. See exceptions and specific conditions at the end of this work programme part

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

For application of the general award criteria, including weighting and thresholds, see the specific conditions at the end of this Work Programme part.

Documents

The documents are described in General Annex E.

Procedure

The general procedure is described in General Annex F. See exceptions and specific conditions at the end of this work programme part

Expected EU contribution per project

The expected EU contribution depends on the number of person-months requested. For the applicable unit contributions, see specific conditions for MSCA at the end of this Work Programme part.

Legal and financial set-up of the Grant Agreements

The general conditions are described in General Annex G. See exceptions and specific conditions at the end of this Work Programme part.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2026-SE-01-01: MSCA Staff Exchanges 2026

Expected Outcome:

Project results are expected to contribute to the following outcomes:

For staff members

1.Increased set of research and transferable skills and competences, leading to improved employability and career prospects within and outside academia;

2.More knowledge and innovative ideas converted into products, processes and services;

3.More entrepreneurial mind-sets, testing new and innovative ideas;

4.Increased international exposure leading to extended networks and opportunities;

5.Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.

For participating organisations

1.Innovative ways of cooperation and transfer of knowledge between sectors and disciplines;

2.Strengthened and broader international, inter-sectoral and interdisciplinary collaborative networks;

3.Boosted R&I capacity

Scope: MSCA Staff Exchanges involve organisations from the academic and non-academic sectors (including SMEs) from across the globe. International cooperation through the participation of organisations from non-associated third countries is strongly encouraged.

Support is provided for international, inter-sectoral and interdisciplinary mobility of R&I staff leading to knowledge transfer between participating organisations.

Mobility through secondments

The organisations constituting the partnership contribute directly to the implementation of a joint R&I project by seconding and/or hosting eligible staff members. Such a project must explore activities that can be based on previous work but should go beyond and generate or strengthen long-term collaborations. Secondments must involve physical mobility 44 of the eligible staff members and must always take place between legal entities independent from each other.

MSCA Staff Exchanges can address different dimensions of mobility: international, inter-sectoral and interdisciplinary 45 . Exchanges between organisations within EU Member States and Horizon Europe Associated Countries should mainly be inter-sectoral, but same-sector exchanges are also possible. Interdisciplinarity is particularly encouraged for secondments between academic organisations.

The collaborative approach of MSCA Staff Exchanges should exploit complementary competences of the participating organisations and create synergies between them. The secondments should be essential to achieve the joint project’s R&I activities. The project should inter alia enable networking activities and the organisation of workshops and conferences, to facilitate sharing of knowledge and testing of innovative approaches for specific R&I topics.

Skills’ development

For participating staff members, the project should offer new skills acquisition and career development perspectives. Participating organisations must ensure that the seconded staff are adequately mentored. Proposals should clearly describe how planned international, intersectoral and interdisciplinary secondments will expose seconded staff to different skills, working cultures or career trajectories.

Call - MSCA Staff Exchanges 2027

HORIZON-MSCA-2027-SE-01

Conditions for the Call

Indicative budget(s) 46

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million)

Indicative number of projects expected to be funded

2027

Opening: 15 Dec 2026

Deadline(s): 15 Apr 2027

HORIZON-MSCA-2027-SE-01-01

TMA Staff Exchanges

95.04

Not relevant

Overall indicative budget

95.04

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A. See exceptions and specific conditions at the end of this work programme part.

Eligibility conditions

The general conditions are described in General Annex B. See exceptions and specific conditions at the end of this work programme part

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

For application of the general award criteria, including weighting and thresholds, see the specific conditions at the end of this Work Programme part.

Documents

The documents are described in General Annex E.

Procedure

The general procedure is described in General Annex F. See exceptions and specific conditions at the end of this work programme part

Expected EU contribution per project

The expected EU contribution depends on the number of person-months requested. For the applicable unit contributions, see specific conditions for MSCA at the end of this Work Programme part.

Legal and financial set-up of the Grant Agreements

The general conditions are described in General Annex G. See exceptions and specific conditions at the end of this Work Programme part.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2027-SE-01-01: MSCA Staff Exchanges 2027

Expected Outcome: Project results are expected to contribute to the following outcomes:

For staff members

1.Increased set of research and transferable skills and competences, leading to improved employability and career prospects within and outside academia;

2.More knowledge and innovative ideas converted into products, processes and services;

3.More entrepreneurial mind-sets, testing new and innovative ideas;

4.Increased international exposure leading to extended networks and opportunities;

5.Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.

For participating organisations

1.Innovative ways of cooperation and transfer of knowledge between sectors and disciplines;

2.Strengthened and broader international, inter-sectoral and interdisciplinary collaborative networks;

3.Boosted R&I capacity.

Scope: MSCA Staff Exchanges involve organisations from the academic and non-academic sectors (including SMEs) from across the globe. International cooperation through the participation of organisations from non-associated third countries is strongly encouraged.

Support is provided for international, inter-sectoral and interdisciplinary mobility of R&I staff leading to knowledge transfer between participating organisations.

Mobility through secondments

The organisations constituting the partnership contribute directly to the implementation of a joint R&I project by seconding and/or hosting eligible staff members. Such a project must explore activities that can be based on previous work but should go beyond and generate or strengthen long-term collaborations. Secondments must involve physical mobility 47 of the eligible staff members and must always take place between legal entities independent from each other.

MSCA Staff Exchanges can address different dimensions of mobility: international, inter-sectoral and interdisciplinary 48 . Exchanges between organisations within EU Member States and Horizon Europe Associated Countries should mainly be inter-sectoral, but same-sector exchanges are also possible. Interdisciplinarity is particularly encouraged for secondments between academic organisations.

The collaborative approach of MSCA Staff Exchanges should exploit complementary competences of the participating organisations and create synergies between them. The secondments should be essential to achieve the joint project’s R&I activities. The project should inter alia enable networking activities and the organisation of workshops and conferences, to facilitate sharing of knowledge and testing of innovative approaches for specific R&I topics.

Skills’ development

For participating staff members, the project should offer new skills acquisition and career development perspectives. Participating organisations must ensure that the seconded staff are adequately mentored. Proposals should clearly describe how planned international, intersectoral and interdisciplinary secondments will expose seconded staff to different skills, working cultures or career trajectories.

MSCA Co-funding of regional, national and international programme

MSCA COFUND co-finances new or existing doctoral programmes and postdoctoral fellowship schemes with the aim of spreading the best practices of the MSCA including international, inter-sectoral and interdisciplinary research training, as well as international and cross-sectoral mobility of researchers at all stages of their career.

In practice, MSCA COFUND provides complementary funding for doctoral or postdoctoral programmes managed by entities established in EU Member States or Horizon Europe Associated Countries. Those co-funded programmes must follow MSCA’s good practice in terms of international recruitment and minimum standard of employment for the recruited fellows as described in the European Charter for Researchers.

MSCA Choose Europe for Science co-funded programmes additionally aim to address brain drain and precarity of researchers' careers in order to make Europe more attractive to the most promising young talents. The scheme will allow applicants to link MSCA grants to competitions leading to long-term attractive positions in universities and other research performing organisations.

Expected impact

Proposals under this Action should contribute to the following expected impacts:

1.Enhance talent and knowledge circulation across the R&I landscape, through international, inter-sectoral and interdisciplinary mobility, including by supporting regional or national smart specialisation strategies when appropriate;

2.Align practices with MSCA policies based on the European Charter for Researchers;

3.Improve the attractiveness of researchers’ careers notably through better working and employment conditions as well as access to concrete long-term career prospects;

4.Strengthen Europe's human capital base in R&I by training highly-skilled researchers;

5.Increase Europe's attractiveness as a leading R&I destination;

6.Enhance the quality of R&I contributing to Europe's sustainable competitiveness;

7.Establish sustainable collaboration between academic and non-academic organisations;

8.Foster the culture of open science, innovation and entrepreneurship.

The following call(s) in this work programme contribute to this Action:

Call

Budgets (EUR million)

Deadline(s)

2026

2027

HORIZON-MSCA-2026-COFUND-01

105.46

08 Apr 2026

HORIZON-MSCA-2027-COFUND-01

51.25

06 Apr 2027

HORIZON-MSCA-2027-COFUND-02

51.25

06 Apr 2027

Overall indicative budget

105.46

102.50

Call - MSCA COFUND 2026

HORIZON-MSCA-2026-COFUND-01

Conditions for the Call

Indicative budget(s) 49

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million)

Indicative number of projects expected to be funded

2026

Opening: 16 Dec 2025

Deadline(s): 08 Apr 2026

HORIZON-MSCA-2026-COFUND-01-01

TMA-Cofund-Doctoral

105.46

Not relevant

HORIZON-MSCA-2026-COFUND-01-01

TMA-Cofund-Postdoctoral

105.46

Not relevant

Overall indicative budget

105.46

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A. See exceptions and specific conditions at the end of this work programme part.

Eligibility conditions

The general conditions are described in General Annex B. See exceptions and specific conditions at the end of this work programme part

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

For application of the general award criteria, including weighting and thresholds, see the specific conditions at the end of this Work Programme part.

Documents

The documents are described in General Annex E.

Procedure

The general procedure is described in General Annex F. See exceptions and specific conditions at the end of this work programme part

Expected EU contribution per project

The expected EU contribution depends on the number of person-months requested. For the applicable unit contributions, see specific conditions for MSCA at the end of this Work Programme part.

Legal and financial set-up of the Grant Agreements

The general conditions are described in General Annex G. See exceptions and specific conditions at the end of this Work Programme part.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2026-COFUND-01-01: MSCA COFUND 2026

Expected Outcome: Projects results are expected to contribute to the following outcomes:

For supported doctoral candidates or postdoctoral researchers

1.Deeper and more diverse set of research-related and transferable skills and competences;

2.Improved employability and career prospects both within academia and beyond;

3.New mind-sets and approaches to R&I work forged through international, inter-sectoral and interdisciplinary experience;

4.Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.

For participating organisations

1.Enhanced quality and sustainability of research training;

2.Increased global attractiveness, visibility and reputation of the participating organisation(s);

3.Stronger R&I capacity and output among participating organisations;

4.Increased contribution of the participating organisations to the local, regional and/or national socio-economic ecosystems;

5.Regular feedback of research results into teaching and education at participating organisations

Scope: Applicants submit proposals for new or existing doctoral or postdoctoral programmes with an impact on the enhancement of human resources in R&I at regional, national or international level. These programmes will be co-funded by MSCA COFUND.

Proposed programmes can cover any research disciplines ("bottom-up"), but exceptionally can also focus on specific disciplines, notably when they are based on national or regional Research and Innovation Strategies for Smart Specialisation (RIS3 strategies). In this case, the range of covered disciplines should allow reasonable flexibility for the researchers to define their topic.

Funding synergies with Cohesion Policy Funds and other EU funding sources are strongly encouraged.

A Career Development Plan must be jointly established by the supervisor and each recruited researcher upon recruitment. In addition to research objectives, this Plan comprises the researcher's training and career needs, including training on transferable skills, teaching, planning for publications and participation in conferences and events aimed at opening science and research to citizens. The Plan must be established at the beginning of the recruitment and should be revised (and updated where needed) within 18 months.

COFUND takes the form of:

A) Doctoral programmes

Doctoral programmes offer research training activities to allow doctoral candidates to develop and broaden their skills and competences. They will lead to the award of a doctoral degree in at least one EU Member State or Horizon Europe Associated Country. The training activities should be based on the EU Principles on Innovative Doctoral Training .

The doctoral programmes should develop substantial training modules, addressing key transferable skills and competences common to all fields, including digital ones (e.g. generative AI) and fostering the culture of Open Science, knowledge valorisation 50 , and when applicable innovation and entrepreneurship as well as good scientific conduct such as research integrity. In particular, doctoral programmes should adequately prepare doctoral candidates to pursue a career in research and adequately prepare them for increased research collaboration and information-sharing made possible by new (digital) technologies (e.g. collaborative tools, opening access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science, etc.).

On top of compulsory international mobility, applicants are encouraged to include elements of cross-sectoral mobility and interdisciplinarity into their programmes. Collaboration with a wider set of associated partners, including from the non-academic sector, will be positively taken into account during the evaluation. These organisations may provide hosting or secondment opportunities or training modules in research or transferable skills.

Particular attention is paid to the quality of supervision and mentoring arrangements as well as career guidance. The selection procedure for doctoral candidates must be open, transparent and merit-based, in line with the European Charter for Researchers. The vacancy notice (to be widely advertised internationally, including on the EURAXESS 51 website) must mention if the published rates include all employer and employee's taxes and contributions. If possible, the gross salary (net salary + employee’s taxes and contributions) should be published.

B) Postdoctoral Programmes

Postdoctoral programmes fund individual advanced research training and career development fellowships for postdoctoral researchers. The programmes should offer training to develop key transferable skills and competences common to all fields, including digital ones (e.g. generative AI), and foster the culture of Open Science, knowledge valorisation 52 , and when applicable innovation and entrepreneurship, as well as good scientific conduct such as research integrity. In particular, the postdoctoral programmes should empower fellows to pursue a career in research and adequately prepare them for increased research collaboration and information-sharing made possible by new (digital) technologies (e.g. collaborative tools, opening access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science, etc.).

Postdoctoral programmes should have regular selection rounds following fixed deadlines or regular cut-off dates, allowing fair competition between researchers. The selection procedure for postdoctoral candidates must be open, merit-based and with a transparent international peer review, in line with the European Charter for Researchers. The vacancy notice (to be widely advertised internationally, including on the EURAXESS website) must mention if the published rates include all employer and employee's taxes and contributions. If possible, the gross salary (net salary + employee’s taxes and contributions) should be published.

On top of compulsory international mobility, applicants are encouraged to include elements of cross-sectoral mobility and interdisciplinarity into their programmes. Researchers will be able to freely choose a research topic and the appropriate organisation to host them, fitting their individual needs.

Call - MSCA COFUND 2027

HORIZON-MSCA-2027-COFUND-01

Conditions for the Call

Indicative budget(s) 53

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million)

Indicative number of projects expected to be funded

2027

Opening: 08 Dec 2026

Deadline(s): 06 Apr 2027

HORIZON-MSCA-2027-COFUND-01-01

TMA-Cofund-Doctoral

51.25

Not relevant

Overall indicative budget

51.25

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A. See exceptions and specific conditions at the end of this work programme part.

Eligibility conditions

The general conditions are described in General Annex B. See exceptions and specific conditions at the end of this work programme part

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

For application of the general award criteria, including weighting and thresholds, see the specific conditions at the end of this Work Programme part.

Documents

The documents are described in General Annex E.

Procedure

The general procedure is described in General Annex F. See exceptions and specific conditions at the end of this work programme part

Expected EU contribution per project

The expected EU contribution depends on the number of person-months requested. For the applicable unit contributions, see specific conditions for MSCA at the end of this Work Programme part.

Legal and financial set-up of the Grant Agreements

The general conditions are described in General Annex G. See exceptions and specific conditions at the end of this Work Programme part.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2027-COFUND-01-01: MSCA COFUND 2027

Expected Outcome: Projects results are expected to contribute to the following outcomes:

For supported doctoral candidates

1.Deeper and more diverse set of research-related and transferable skills and competences;

2.Improved employability and career prospects both within academia and beyond;

3.New mind-sets and approaches to R&I work forged through international, inter-sectoral and interdisciplinary experience;

4.Enhanced networking and communication capacities with scientific peers, as well as with the general public that will increase and broaden the research and innovation impact.

For participating organisations

1.Enhanced quality and sustainability of research training;

2.Increased global attractiveness, visibility and reputation of the participating organisation(s);

3.Stronger R&I capacity and output among participating organisations;

4.Increased contribution of the participating organisations to the local, regional and/or national socio-economic ecosystems;

5.Regular feedback of research results into teaching and education at participating organisations.

Scope: Applicants submit proposals for new or existing doctoral programmes with an impact on the enhancement of human resources in R&I at regional, national or international level. These programmes will be co-funded by MSCA COFUND.

Proposed programmes can cover any research disciplines ("bottom-up"), but exceptionally can also focus on specific disciplines, notably when they are based on national or regional Research and Innovation Strategies for Smart Specialisation (RIS3 strategies). In this case, the range of covered disciplines should allow reasonable flexibility for the researchers to define their topic.

Funding synergies with Cohesion Policy Funds and other EU funding sources are strongly encouraged.

A Career Development Plan must be jointly established by the supervisor and each recruited researcher upon recruitment. In addition to research objectives, this Plan comprises the researcher's training and career needs, including training on transferable skills, teaching, planning for publications and participation in conferences and events aimed at opening science and research to citizens. The Plan must be established at the beginning of the recruitment and should be revised (and updated where needed) within 18 months.

Doctoral programmes offer research training activities to allow doctoral candidates to develop and broaden their skills and competences. They will lead to the award of a doctoral degree in at least one EU Member State or Horizon Europe Associated Country. The training activities should be based on the EU Principles on Innovative Doctoral Training .

The doctoral programmes should develop substantial training modules, addressing key transferable skills and competences common to all fields, including digital ones (e.g. generative AI) and fostering the culture of Open Science, knowledge valorisation 54 , and when applicable innovation and entrepreneurship as well as good scientific conduct such as research integrity. In particular, doctoral programmes should adequately prepare doctoral candidates to pursue a career in research and adequately prepare them for increased research collaboration and information-sharing made possible by new (digital) technologies (e.g. collaborative tools, opening access to publications and to other research outputs including data, FAIR data management, societal engagement and citizen science, etc.).

On top of compulsory international mobility, applicants are encouraged to include elements of cross-sectoral mobility and interdisciplinarity into their programmes. Collaboration with a wider set of associated partners, including from the non-academic sector, will be positively taken into account during the evaluation. These organisations may provide hosting or secondment opportunities or training modules in research or transferable skills.

Particular attention is paid to the quality of supervision and mentoring arrangements as well as career guidance. The selection procedure for doctoral candidates must be open, transparent and merit-based, in line with the European Charter for Researchers. The vacancy notice (to be widely advertised internationally, including on the EURAXESS 55 website) must mention if the published rates include all employer and employee's taxes and contributions. If possible, the gross salary (net salary + employee’s taxes and contributions) should be published.

Call - MSCA Choose Europe for Science 2027

HORIZON-MSCA-2027-COFUND-02

Conditions for the Call

Indicative budget(s) 56

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million)

Indicative number of projects expected to be funded

2027

Opening: 08 Dec 2026

Deadline(s): 06 Apr 2027

HORIZON-MSCA-2027-COFUND-02-01

TMA-Cofund-Postdoctoral

51.25

Not relevant

Overall indicative budget

51.25

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A. See exceptions and specific conditions at the end of this work programme part.

Eligibility conditions

The general conditions are described in General Annex B. See exceptions and specific conditions at the end of this work programme part

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

For application of the general award criteria, including weighting and thresholds, see the specific conditions at the end of this Work Programme part.

Documents

The documents are described in General Annex E.

Procedure

The general procedure is described in General Annex F. See exceptions and specific conditions at the end of this work programme part

Expected EU contribution per project

The expected EU contribution depends on the number of person-months requested. For the applicable unit contributions, see specific conditions for MSCA at the end of this Work Programme part.

Legal and financial set-up of the Grant Agreements

The general conditions are described in General Annex G. See exceptions and specific conditions at the end of this Work Programme part.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2027-COFUND-02-01: MSCA Choose Europe for Science 2027

Expected Outcome: For supported researchers:

1.Concrete career prospects and increased career stability;

2.Deeper and more diverse set of research-related, academic and transferable skills and competences, leading to greater autonomy.

For participating organisations:

1.Better alignment of research and Human Resources practices, including recruitment, career accession and progression systems, at participating organisation(s) with the European Charter for Researchers and the Council Recommendation of 18 December 2023 on a European framework to attract and retain research, innovation and entrepreneurial talents in Europe and the Agreement on Reforming Research Assessment;

2.Increased global attractiveness, visibility and reputation of the participating organisation(s);

3.Stronger R&I and teaching capacity and output;

4.Increased contribution to the local, regional and/or national socio-economic ecosystems;

5.Stronger synergies across institutional research, management and teaching structures.

Scope: The objective of this scheme is to tackle brain drain and precarity of researchers' careers to make Europe more attractive to the most promising young talents. Applicants submit proposals for talent recruitment programmes that will provide researchers holding a doctoral degree with excellent research and academic opportunities, potentially coupled with management activities, to lead them to concrete and attractive career prospects. This will have an impact on the enhancement of human resources in R&I at institutional, regional, national or international level. These programmes will be co-funded by MSCA Choose Europe for Science.

The programmes will be divided into two phases. An EU-funded phase (24-36 months) in which the EU funding will cover direct and indirect costs related to the implementation of the programme and a phase funded fully by the beneficiary (24 months) in which the applicant is expected to set salaries attractive at a national level and ensure availability of the necessary internal or external funds to implement the project. Applicants should specify the order of the two phases in their proposals.

Proposed programmes can cover any research disciplines. The selection procedure for candidates must be open, merit-based and with a transparent international peer-review in line with the European Charter for Researchers 57 . Alignment with the principles outlined in the Agreement on Reforming Research Assessment 58 is also encouraged. Selection criteria should be based primarily on excellence. Additional selection criteria require clear alignment with local human resources needs identified in the relevant institutional, regional or national strategies. These must be described in the proposal and must be listed in the vacancy notice (to be widely advertised internationally, including on the EURAXESS website 59 ) alongside the gross salaries applicable to the two programme phases (net salary + employee’s taxes and contributions). Selected fellows will be able to define their own research topic at their host institution(s) and take on teaching or management tasks where relevant. The programmes should aim at offering excellent working conditions to researchers, including salary, professional resources, and career development.

The career development should incorporate transversal skills but also job-specific skills and, where relevant, language courses to ensure that the training is in line with the career opportunities offered following the fellowship. These opportunities must include concrete and attractive long-term career prospects, such as pathways towards open-ended contracts, which can be subject to assessment and evaluation. There must be a fair, equal, inclusive, transparent, structured career accession and progression system providing access to these opportunities in line with the Council Recommendation of 18 December 2023 on a European framework to attract and retain research, innovation and entrepreneurial talents in Europe, the European Charter for Researchers in its annex and the Agreement on Reforming Research Assessment.

A Career Development Plan must be maintained throughout the period of the Choose Europe for Science programme. This Plan comprises the researcher's career development needs, including training on languages, transferable skills, teaching, planning for publications and participation in conferences and events. The Plan should outline the projected career progression paths in the host institution.

MSCA and Citizens

MSCA and Citizens aims to bring research and researchers closer to the public at large, to increase awareness of research and innovation activities and to boost public recognition of science and research education. It will show the role of the researcher for the society and economy, as well as the impact of researchers’ work on citizens’ daily lives. It also aims to raise the interest of young people in research and scientific careers.

MSCA and Citizens will address the general public, attracting people regardless of the level of their scientific background, with a specific focus on families, pupils, students, and notably those who do not have easy access to, and thus are less inclined to engage in, STEAM fields (science, technology, engineering, arts and mathematics) or research activities. Inclusiveness should be key, in view of broadening access to science and research to all.

MSCA and Citizens should also promote gender balance and inclusiveness in science, Open Science, and Responsible Research and Innovation.

These objectives will be pursued through the organisation of the European Researchers’ Night and the implementation of the Researchers at Schools initiative.

The European Researchers’ Night is the largest research communication and promotion event taking place across EU Member States and Horizon Europe Associated Countries. A wide geographic coverage that reflects the European nature of this initiative is key.

The Researchers at Schools initiative aims to strengthen the connection between research and education. It brings school classes to research facilities and researchers to schools or other pedagogical and educational centres, encouraging interaction with pupils at all levels of education. Researchers and pupils will meet to talk about current and future challenges of our societies and the related key role of research. Pupils will learn directly about research projects and activities addressing the EU priorities and main orientations.

Expected impact

Proposals under this Action should contribute to the following expected impacts:

1.Enhance engagement with citizens on R&I;

2.Increase awareness among the general public of the importance and benefits of R&I, especially EU-funded research, and its concrete impact on citizens’ daily life;

3.Contribute to the diffusion and the promotion of excellence research projects across Europe and beyond by reaching citizens in as many participating countries as possible;

4.Raise the interest of young people in science and research careers;

5.Support school teachers and educators by showcasing real-life applications of research projects and creating a learning opportunity for pupils through a direct interaction with researchers.

The following call(s) in this work programme contribute to this Action:

Call

Budgets (EUR million)

Deadline(s)

2027

HORIZON-MSCA-2027-CITIZENS-01

15.71

08 Jun 2027

Overall indicative budget

15.71

Call - MSCA and Citizens 2027

HORIZON-MSCA-2027-CITIZENS-01

Conditions for the Call

Indicative budget(s) 60

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 61

Indicative number of projects expected to be funded

2027

Opening: 09 Mar 2027

Deadline(s): 08 Jun 2027

HORIZON-MSCA-2027-CITIZENS-01-01

CSA

15.71

0.10 to 0.35

50

Overall indicative budget

15.71

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Proposals are invited against the following topic(s):

HORIZON-MSCA-2027-CITIZENS-01-01: MSCA and Citizens 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 0.10 and 0.35 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 15.71 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply: Activities carried-out in non-associated third countries are not eligible for funding.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering the widest geographical coverage with events and activities held in as many eligible countries as possible, grants will be awarded to applications not only in order of ranking but at least also to each application that is highest ranked per country based on where the coordinator is established (including trans-national consortia), provided that the applications attain all thresholds

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs may take form of lump sum contributions as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie Actions under the Horizon Europe Programme.

Expected Outcome: Project results are expected to contribute to the following outcomes:

For researchers

1.Enhanced opportunities to interact with citizens and local, regional and national authorities;

2.Improved communication skills and competences to interact with a non-research audience, notably with pupils and students.

For organisations

1.Increased reputation and visibility of participating organisations in terms of hosting excellent research projects towards the general public and possible future students;

2.Researchers’ work made more tangible, concrete, accessible, and thus opening research and science to all;

3.Improved outreach to all audiences across Europe, and notably those who do not have an easy access to science and research activities;

4.Better communication of R&I results and activities to society, increased and strengthened opportunities for citizens’ engagement.

Scope: Proposals should cover both the organisation of the European Researchers’ Night and the implementation of the Researchers at Schools initiative.

The European Researchers' Night takes place every year, on the last Friday of September. It supports events that can last up to two days: they can start on Friday and continue the following day. Pre-events, prior to the main event, and related post-events, such as wrap-up meetings or small-scale follow-up events, can also be organised. It is the occasion for a Europe-wide public and media event for the promotion of research careers.

The European Researchers’ Night targets the general public, addressing and attracting people regardless of the level of their scientific background, with a special focus on young people and their families, pupils and students, and notably those who do not have easy access to, and thus are less inclined to engage in STEAM fields (science, technology, engineering, arts and mathematics) or research activities.

The Researchers at Schools initiative brings school classes to research facilities and researchers to schools or other pedagogical and educational centres. This allows researchers to interact with pupils on societal challenges and on the key role of research to address them. Pupils will thus learn directly about research projects.

Types of activities

European Researchers’ Night activities can combine education with entertainment, especially when addressing young audiences. They can take various forms, such as exhibitions, hands-on experiments, science shows, simulations, debates, games, competitions, quizzes, etc. Where appropriate, engagement with educational institutions should be sought in order to encourage formal and informal science education with the aim of improving the scientific knowledge base. The European Researchers’ Night should be highlighted as a European and Europe-wide event. Additionally, each proposal should promote the European Union, EU-funded research and its impact on citizens’ daily life in the most appropriate way, according to the set-up and the configuration of the event, its location and its activities.

Researchers at Schools activities will allow researchers to showcase their work and interact with pupils. They can take various forms, such as presentations, discussions, speed-dating, citizen science, science shows, summer schools, nature walks or visits to research facilities. Where appropriate, researchers should receive training ahead of the activities on science communication, especially targeting a young audience. The Researchers at Schools activities should take place at any time during the project duration and should be subject to a dedicated promotion, particularly towards schools and other pedagogical and educational centres.

Involvement of researchers funded by Horizon Europe or previous Framework Programmes, notably by the Marie Skłodowska-Curie Actions, is highly encouraged.

Both the European Researchers’ Night and Researchers at Schools initiative should promote gender balance, diversity and inclusiveness in science in terms of planned activities and researchers involved.

Partnerships and coordination at regional, national or cross-border levels will be strongly encouraged aiming at a good geographical spread and avoiding overlaps.

Where appropriate, synergies should be sought with the newly created Science Comes To Town initiative, implemented through Work Programme Annex 11, Widening Participation and Strengthening the European Research Area.

High-quality applications not retained due to lack of funding may be granted the status of associated events.

Eligible costs will take the form of lump sum contributions as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

The maximum requested EU contribution per proposal should not exceed EUR 350 000. All proposals are encouraged to bring additional sources of funding. The budget will be evaluated under the criterion 3 “Quality and efficiency of the implementation”. Proposals that exceed this maximum EU contribution might be penalised during the evaluation unless a strong justification is provided.

Applicants are encouraged to submit proposals covering activities for both 2028 and 2029, including the organisation of two successive editions (2028 and 2029) of the European Researchers’ Night and implementation of Researchers at Schools activities during the project duration. Applicants should clearly state how they will communicate and promote the European nature of this action.

Other Actions not subject to calls for proposals

Grants not subject to calls for proposals

1. MSCA Irish Presidency event 2026

On the 30th anniversary year of the Marie Sklodowska-Curie Programme, this conference will explore the impact of the Marie Skłodowska-Curie Actions and how the MSCA can evolve to support resilient, attractive, and future-proof research careers amid growing global uncertainty. With geopolitical tensions and shifting global alliances, Europe’s ability to attract, develop, and retain top research talent is more vital than ever. This conference will work towards building cohesion and collaboration within the European research ecosystem as well as across the global system.

Key themes will include:

1.Building research careers that can withstand external shocks and systemic volatility

2.Ensuring and strengthening mobility and collaboration across borders

3.Enhancing the attractiveness of European research careers to global talent

4.An inclusive research environment that supports European innovation and competitiveness

5.Strengthening institutional support systems to empower researchers in uncertain times

6.Recognising the realities of precarity and the need to strengthen long-term career pathways across academia and industry.

The event will bring together policymakers, MSCA fellows and alumni, institutions, and international partners to shape a talent strategy that not only responds to today’s challenges but positions Europe as a global leader in research excellence and career development for the decade ahead.

Legal entities:

Taighde Éireann – Research Ireland, Three Park Place, Hatch Street Upper, Dublin 2, Ireland, D02 FX65

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

Indicative timetable: Fourth quarter 2026

Indicative budget: EUR 0.20 million from the 2026 budget

2. MSCA Lithuanian Presidency event 2027

As the European Research Area (ERA) Policy Agenda 2025–2027 advances and Horizon Europe enters its final year in 2027, this is a timely opportunity to engage in strategic dialogue on how the Marie Skłodowska-Curie Actions (MSCA) can continue to support and shape the future ERA.

This high-level conference will bring together policymakers, research institutions, and key stakeholders to reflect on the achievements of the current ERA framework and explore MSCA’s critical role in implementing the ERA Pact and realising renewed ERA priorities.

The event will emphasise MSCA’s longstanding contribution to Europe’s global competitiveness in research and innovation. In a rapidly evolving global environment, the MSCA remains a cornerstone of EU efforts to attract and retain top talent, promote research excellence, and support systemic capacity building across Member States and Associated Countries. The scheme’s bottom-up, researcher-driven approach ensures that curiosity-led research continues to thrive, fostering innovative solutions to current and future societal challenges.

The conference will serve as a policy-focused forum to assess the strategic alignment between MSCA and ERA goals, particularly in relation to balanced talent circulation, brain gain, and institutional excellence. It will explore how MSCA can further reinforce the ERA Pact’s shared values, commitments, and monitoring tools, and how it can remain a central instrument in the next Framework Programme for supporting an open, cohesive, and competitive European Research Area.

Legal entities:

Research Council of Lithuania (RCL), Gedimino pr. 3, Vilnius, 01103, Vilniaus m. sav., Lithuania

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

Indicative timetable: Second quarter of 2027

Indicative budget: EUR 0.20 million from the 2027 budget

3. Support to the Marie Curie Alumni Association

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation. The use of a grant to identified beneficiary is justified by the particular role and purpose of the MCAA, its unique nature and the fact that the association gathers around 20.000 MSCA alumni.

This action should support the MCAA in achieving the following objectives:

1.Supporting the functioning of the MCAA, foster its expansion and growth on the European and international stage;

2.Facilitating professional networking and career development of former and current MSCA fellows;

3.Encouraging networking and cooperation among members from different countries, sectors of the economy and across scientific disciplines;

4.Enabling alumni to act as MSCA ambassadors and promoters within the global research and innovation community, but also for the European Commission and EU Delegations throughout the world;

5.Provide feedback to the European Commission on the MSCA to constantly improve its success, relevance and impact; and provide feedback on relevant EU policies.

The beneficiary may provide financial support to third parties (including individual members of the MCAA as well as Working Groups and Chapters). The support to third parties can be provided in the form of grants, prizes or similar forms of support. The support should be at least 30% and no more than 50% of the maximum grant amount for activities such as travel, development and production of media materials related to the MCAA. The condition for financial support to third parties outlined in General Annex B requiring that all calls for third parties must be published on the Funding & Tenders Portal, does not apply.

Eligible activities under this grant include inter alia:

1.Organisation of physical and virtual MCAA governance body meetings according to the need of the MCAA;

2.Organisation of General Assembly meetings of the MCAA and annual MCAA Conference;

3.Support for Alumni, Chapters and Working groups;

4.Maintenance and continuous development of the MCAA’s IT infrastructure and website, including the membership database;

5.Data collection and provision of structured feedback on the MSCA, including online surveys, in agreement with the Commission, to obtain feedback on EU policy topics, on the MSCA, on the development of the network or any other topic of interest to both parties.

The following deliverables will have to be submitted:

1.Yearly work plans on the functioning and growth of the MCAA submitted at month 12 and updated at month 24;

2.A long-term plan for the evolution of the MCAA submitted at month 15, and updated at month 28;

3.A communication plan to be submitted 10 months after the beginning of the grant;

4.A progress report at month 14 and month 26.

The expected duration of the action is 36 months.

The evaluation committee will be composed fully by representatives of EU institutions. The evaluation committee can be assisted by external experts if required.

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes.

Eligible costs may take form of lump sum contributions as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie Actions under the Horizon Europe Programme.

Legal entities:

MCAA-Marie Curie Alumni Association, MCAA, c/o Inovamais, Avenue des Arts, 24, B-1000 Brussels, Belgium

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

Indicative budget: EUR 4.00 million from the 2027 budget

4. MSCA Special needs Allowances to Horizon 2020 legacy projects

The MSCA pay particular attention to accessibility and inclusiveness and foresee financial support for the additional costs entailed by recruited or seconded researchers/staff members with disabilities whose long-term physical, mental, intellectual or sensory impairments 62 are as such that their participation in MSCA would not be possible without extra financial support.

Beneficiaries of Horizon 2020 ITN, IF, RISE and COFUND grants can continue to apply for a dedicated special needs grant. This grant will cover the additional costs that researchers/staff members with disabilities face due to the increased costs of their mobility. It can also be used to ensure necessary assistance by third persons or for adapting their work environment 63 . It cannot cover costs which are already covered by another source, such as social security or health insurance.

The support will be granted based on the request submitted by the coordinator of the MSCA grant (Horizon 2020 ITN, IF, RISE and COFUND grants) to the granting authority. The request can be submitted at any moment during the implementation of the MSCA grant, when the need arises. The request should contain a description of the special needs, the type of support and the budget requested. The request will be evaluated by the granting authority and, if needed, an assistance by external experts may be requested.

Once agreed, the MSCA grant agreement will be formally amended and the requested amount for the special needs will be covered by the increase of the budget in the Management cost category. This extra amount will be paid together with the payment of the balance. The support will be limited to a maximum of EUR 60 000 per researcher/staff member.

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

Indicative timetable: Throughout 2026 and 2027

Indicative budget: EUR 0.20 million from the 2026 budget

Procurements

1. Public Procurement for Events and Outreach

During 2026 and 2027, the Commission will organise several events (conferences and workshops) dedicated to the Marie Skłodowska-Curie Actions and to contribute to leading research conferences. Moreover, a dedicated campaign will be organised to ensure the visibility of the Marie Skłodowska-Curie Actions and funded projects to the general public.

Form of Funding: Procurement

Type of Action: Public procurement

Indicative budget: EUR 0.50 million from the 2026 budget and EUR 0.50 million from the 2027 budget

Other budget implementation instruments

1. External Expertise

This action will support the use of appointed independent experts for the monitoring of ongoing actions (grant agreements, grant decisions, public procurement actions, financial instruments) funded under Horizon Europe and previous Framework Programmes for Research and Innovation and where appropriate include ethics checks, as well as compliance checks regarding the Gender Equality Plan eligibility criterion.

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative budget: EUR 0.50 million from the 2026 budget and EUR 0.50 million from the 2027 budget

Budget 64

Budget line(s)

2026 Budget (EUR million)

2027 Budget (EUR million)

Calls

HORIZON-MSCA-2026-DN-01

593.03

from 01.020102

593.03

HORIZON-MSCA-2027-DN-01

574.62

from 01.020102

574.62

HORIZON-MSCA-2026-PF-01

399.05

from 01.020102

399.05

HORIZON-MSCA-2027-PF-01

388.57

from 01.020102

388.57

HORIZON-MSCA-2026-SE-01

97.92

from 01.020102

97.92

HORIZON-MSCA-2027-SE-01

95.04

from 01.020102

95.04

HORIZON-MSCA-2026-COFUND-01

105.46

from 01.020102

105.46

HORIZON-MSCA-2027-COFUND-01

51.25

from 01.020102

51.25

HORIZON-MSCA-2027-COFUND-02

51.25

from 01.020102

51.25

HORIZON-MSCA-2027-CITIZENS-01

15.71

from 01.020102

15.71

Other actions

Grant awarded without a call for proposals according to Financial Regulation Article 198(e)

0.40

4.20

from 01.020102

0.40

4.20

Public procurement

0.50

0.50

from 01.020102

0.50

0.50

Expert contract action

0.50

0.50

from 01.020102

0.50

0.50

Estimated total budget

1196.86

1181.63



Specific conditions for the Marie Skłodowska-Curie Actions

DEFINITIONS

The following definitions apply:

'Academic sector' means public or private higher education establishments awarding academic degrees, public or private non-profit research organisations 65 and International European Research Organisations (IERO) 66 .

'Non-academic sector' means any socio-economic actor not included in the academic sector and fulfilling the requirements of the Horizon Europe Rules for Participation.

'Associated partners' are entities which participate in the action, but without the right to charge costs or claim contributions. They contribute to the implementation of the action, but do not sign the grant agreement. Associated partners may not employ the researchers under the action 67 .

'Associated partners linked to a beneficiary' are organisations with an established capital or legal link with the beneficiary, which is not limited to the action nor specifically created for its implementation. These entities implement action tasks described in Annex 1 of the grant agreement, i.e. hosting and training of researchers in Doctoral Networks and Postdoctoral Fellowships and hosting and seconding staff in Staff Exchanges. The associated partners linked to a beneficiary do not have the right to claim unit contributions and may not employ the researcher under the action. In addition, they must fulfil the eligibility conditions 68 for participation and funding applicable to the beneficiary they are linked to. The type of link and involvement of such entities must be clearly described in the proposal and will be assessed as part of the evaluation.

'Beneficiaries' are the legal entities that sign the grant agreement (either directly or through an accession form) and have the responsibility for the proper implementation of the action. They contribute directly to the implementation of the research, transfer of knowledge and training activities. Depending on the type of MSCA action, this involves recruiting, supervising, hosting, training or seconding researchers/research staff or managing and/or funding programmes.

‘Implementing partners’ means third parties implementing the MSCA COFUND doctoral or postdoctoral Programmes and MSCA Choose Europe for Science Programmes by recruiting researchers. Implementing partners can receive financial support from the beneficiary.

For MSCA COFUND, implementing partners that are identified in the proposal must include a letter of commitment before the signature of the grant agreement to ensure their active participation in the action. The involvement of any implementing partner for which no such evidence of commitment is submitted will not be taken into account.

For MSCA Choose Europe for Science, all implementing partners must be identified in the proposal. All implementing partners identified in the proposal must include a letter of commitment before the signature of the grant agreement to ensure their active participation in the action. If such evidence is not submitted, this may put into question the award decision and may lead to the termination of the grant agreement preparation phase. Any change in the composition of the implementing partners after evaluation and grant signature will be accepted only in duly justified very exceptional circumstances.

‘Interdisciplinarity’ means the integration of information, data, techniques, tools, perspectives, concepts or theories from two or more scientific disciplines. The term discipline refers to the first level of MSCA keywords 69 .

1.MSCA DOCTORAL NETWORKS

1.1.Applicable unit contributions

The EU contribution for MSCA Doctoral Networks will take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme 70 .

The following budget categories apply:

MSCA Doctoral Networks

Contributions for recruited researchers

per person-month

Institutional unit contributions

per person-month

Living allowance

Mobility allowance

Family allowance (if applicable)

Long-term leave allowance (if applicable)

Special needs allowance (if applicable)

Research, training and networking contribution

Management and indirect contribution

EUR 4250

EUR 710

EUR 660

EUR 4960 x % covered by the beneficiary

requested unit 71

x (1/number of months)

EUR 1600

EUR 1200

A country correction coefficient applies to the living allowance in order to ensure equal treatment and purchasing power parity for all researchers. This coefficient is the one applicable to the country of the recruiting beneficiary (see Table 1 at the end of this Work Programme part). The living allowance is a gross amount, including compulsory deductions under national law, such as employer and employee social security contributions and direct taxes. The beneficiary must recruit each eligible doctoral candidate under an employment contract or equivalent direct contract, including an instrument of appointment (e.g., for permanent staff and/or officials), with full social security coverage (including sickness, parental, unemployment and invalidity benefits, pension rights, benefits in respect of accidents at work and occupational diseases). An exemption from this rule can be accepted only in cases where national legislation or the equivalent internal regulations of International European Research Organisations (IERO), entities created under Union law, or an international organisation, prohibit this possibility and subject to the prior agreement of the granting authority.

When an employment contract or instrument of appointment cannot be provided, the beneficiary may exceptionally recruit the doctoral candidate under a 'fixed-amount fellowship'. In this case, the living allowance will be halved, and the beneficiary must ensure that the doctoral candidate enjoys minimum social security coverage (including sickness, parental and invalidity benefits, and benefits for accidents at work and occupational diseases).

The beneficiary must pay to the doctoral candidates at least the amount of the living allowance (minus all compulsory deductions under national legislation). A top-up may be paid to the researchers in order to complement this contribution. In addition to the living allowance, all doctoral candidates must receive a mobility allowance. This allowance covers their additional, private mobility-related costs (e.g. travel and accommodation costs), not their professional costs under the action, which are covered by the research, training and networking contribution.

If the recruited doctoral candidate has or acquires family obligations during the action duration, i.e. persons linked to them by (i) marriage, or (ii) a relationship with equivalent status to a marriage recognised by the legislation of the country or region where this relationship was formalised; or (iii) dependent children who are actually being maintained by the researcher, the family allowance must be paid to them as well.

The long-term leave allowance contributes to the personnel costs incurred by the beneficiaries in case of the researchers’ leave, including maternity, paternity, parental, sick or special leave, longer than 30 consecutive days. The special needs allowance contributes to the additional costs for the acquisition of special needs items and services for researchers with disabilities, whose long-term physical, mental, intellectual or sensory impairments 72 are certified by a competent national authority, and of such nature that their participation in the action may not be possible without them (e.g. assistance by third persons, adaptation of work environment, additional travel/transportation costs). These special needs items or services must not have been funded from another source (e.g. social security or health insurance). Both long-term leave and special needs allowances should be requested when the need arises. The research, training and networking contribution should cover, for example, costs for training and networking activities that contribute directly to the researchers’ career development (e.g. participation in conferences, trips related to work on the action, training, language courses, seminars, lab material, books, library records, publication costs), research expenses, visa-related fees and travel expenses, additional costs arising from each secondment of six months or less, which require mobility from the place of residence (e.g. travel and accommodation costs).

The management and indirect contribution should cover the beneficiary’s additional costs in connection with the action (e.g. personnel costs for project management/coordination, indirect costs).

The above rates apply to doctoral candidates devoting themselves to their project on a full-time basis. Researchers may, in agreement with the supervisor and beneficiary and with prior approval by the granting authority, implement their project on a part-time basis. Such a request is limited to personal or family reasons. In cases of part-time work, the doctoral candidates must work at least 50% of the full working time in their recruiting organisation for the action funded by the MSCA 73 . The recruiting beneficiary should report costs as pro rata of the applicable full-time unit contributions. 

1.2.Admissibility

The following exception to the General Annex A applies:

·The page limit of the application is 30 pages (excluding annexes).

1.3.Eligibility

Given the specific nature of MSCA Doctoral Networks, the following exceptions and additional eligibility criteria apply. This section also contains eligibility conditions for unit contributions, which apply during action implementation but cannot be verified at proposal stage.

·All proposals must indicate if they are resubmitted from the previous MSCA Doctoral Networks call under Horizon Europe.

·Proposals submitted to the previous call of MSCA Doctoral Networks under Horizon Europe and having received a score of less than 80% must not be resubmitted the following year.

·Any proposal involving 70% or more of the same recruiting organisations as in another proposal submitted to the previous call of the MSCA Doctoral Networks under Horizon Europe that has received a score of less than 80% will be assessed for whether it is a resubmission, irrespectively of the applicants’ self-declaration.  The assessment will be carried out by external expert evaluators based on the similarity of objectives as well as on the similarity of the scientific approach proposed to reach such objectives.

1.3.1.Participating organisations

·Applications must be submitted by a consortium including at least three independent legal entities, each established in a different EU Member State or Horizon Europe Associated Country and with at least one of them established in an EU Member State. Should none of them be entitled to award a doctoral degree, a university or a consortium/grouping of academic/research institutions entitled to award a doctoral degree must be added to the project as an associated partner or an associated partner linked to a beneficiary.

·Not more than 40.0% of the EU contribution may be allocated to beneficiaries in the same country or to a single International European Research Organisation (IERO) or international organisation.

·International organisations with headquarters in an EU Member State or Horizon Europe Associated Country will be deemed to be established in this Member State or Associated Country.

·Affiliated entities are not allowed to participate as they cannot claim costs in MSCA Doctoral Networks.

·All beneficiaries must recruit at least one doctoral candidate. They are required to host at their premises and supervise recruited researchers, or use associated partners linked to them to do so 74 .

·In order to reach the objectives of Joint Doctorates, at least three independent legal entities must be entitled to award doctoral degrees. At least one of the institutions conferring a joint, double or multiple doctoral degree must be established in an EU Member State and/or Horizon Europe Associated Country. An applicant from the academic sector, which has transferred the right of awarding a doctoral degree to a consortium/grouping of academic/research institutions to which it belongs to, is also eligible. Applicants must provide, at the time of the submission of the proposal, a pre-agreement to award a joint, double or multiple degree to the doctoral candidate(s). The proposal should indicate from which institutions a researcher is expected to receive the degree(s).

·Joint Doctorates must set up a joint governance structure with joint admission, selection, supervision, monitoring and assessment procedures.

·Eligibility to participate is also subject to the ‘Restrictions for the protection of European communication networks’ and ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility conditions (see General Annex B of the General Annexes).

1.3.2.Recruited researchers 75

·Supported researchers must be doctoral candidates, i.e. not already in possession 76 of a doctoral degree at the date of the recruitment. 

·Researchers must be enrolled in a doctoral programme leading to the award of a doctoral degree in at least one EU Member State or Horizon Europe Associated Country. By way of exception, where researchers are recruited by beneficiaries established in non-associated third countries, enrolment may take place solely in a doctoral programme offered in the country of the beneficiary.

·Recruited researchers can be of any nationality and must comply with the following mobility rule: they must not have resided or carried out their main activity 77 (work, studies, etc.) in the country of the recruiting beneficiary for more than 12 months in the 36 months immediately before their recruitment date.

For 'International European Research Organisations' (IERO), 'international organisations', or entities created under Union law, the researchers must not have spent more than 12 months in the 36 months immediately before their recruitment in the same appointing organisation.

·Compulsory national service, short stays such as holidays, time spent by the researcher as part of a procedure for obtaining refugee status under the Geneva Convention 78 and time spent for obtaining EU temporary protection 79 are not taken into account.

·Researchers who, at the date of their recruitment date have refugee status under the Geneva Convention, or benefit from the EU temporary protection are exempt from the mobility rule.

·Secondments are eligible for up to half of the actual months spent implementing the research training activities under the action. This limitation does not apply in the case of Industrial Doctorates and Joint Doctorates.

·In case of industrial doctorates, doctoral candidates must spend at least 50% of their fellowship duration in the non-academic sector.

1.3.3.Duration of the action

·The duration of the action must not exceed 48 months from the starting date set out in the grant agreement (including the time needed to recruit and select the doctoral candidates), except in the case of joint doctorates where this maximum duration is 60 months.

·The duration of each fellowship (on the basis of full-time employment) is minimum 3 and maximum 36 months, except in the case of joint doctorates, where this maximum duration is 48 months.

·The overall EU contribution for MSCA Doctoral Networks actions is limited to a maximum of 540 person-months.

1.4.Award criteria 

·Proposals will be evaluated by experts on the basis of the award criteria 'excellence', 'impact' and 'quality and efficiency of the implementation'.

·Evaluation scores will be awarded for each of these criteria, and not for the different aspects listed in the table below. Each criterion will be scored out of 5. Scores will be awarded with a resolution of one decimal place and will be subject to a weighting factor as indicated in the table below.

·The threshold for individual criteria will be 3.

·Proposals scoring equal to or above 70% will be considered for funding — within the limits of the available call budget. Other proposals will be rejected.

Excellence

Impact

Quality and efficiency
of the implementation

Quality and pertinence of the project’s research and innovation objectives (and the extent to which they are ambitious, and go beyond the state of the art)

Contribution to structuring doctoral training at the European level and to strengthening European innovation capacity, including the potential for:

a) meaningful contribution of the non-academic sector to the doctoral training, as appropriate to the implementation mode and research field

b) developing sustainable elements of doctoral programmes

Quality and effectiveness of the work plan, assessment of risks and appropriateness of the effort assigned to work packages

Soundness of the proposed methodology (including interdisciplinary approaches, consideration of the gender dimension and other diversity aspects if relevant for the research project, and the quality of open science practices)

Credibility of the measures to enhance the career perspectives and employability of researchers and contribution to their skills development

Quality, capacity and role of each participant, including hosting arrangements and extent to which the consortium as a whole brings together the necessary expertise 

Quality and credibility of the training programme (including transferable skills,inter/multidisciplinary inter-sectoral and gender as well as other diversity aspects)

Suitability and quality of the measures to maximise expected outcomes and impacts, as set out in the dissemination and exploitation plan, including communication activities

Quality of the supervision (including mandatory joint supervision for industrial and joint doctorate projects)

The magnitude and importance of the project’s contribution to the expected scientific, societal and economic impacts

50%

30%

20%

Weighting

1.5.Procedure

·Proposals must be submitted to only one of eight 'main evaluation panels': Chemistry (CHE), Social Sciences and Humanities (SOC), Economic Sciences (ECO), Information Science and Engineering (ENG), Environment and Geosciences (ENV), Life Sciences (LIF), Mathematics (MAT), Physics (PHY). Industrial and joint doctorates will be ranked in the scientific panel of submission. Each panel will establish a ranked list.

·The distribution of the indicative budget of the call will be proportional to the number of eligible proposals received in each panel. If the budget allocated to any panel exceeds the requirements of all proposals positively evaluated 80 in that panel, the excess budget will be reallocated to the other panels based on the distribution described above. Equally, if the allocated funding to a panel is insufficient to fund the highest ranked proposal in that panel, the necessary budget will be transferred from the other panels based on the distribution described above, in order to ensure that the highest ranked proposal can be funded. In order to ensure budget optimisation and an equitable success rate across panels, the excess budget remaining after the initial allocation of funding to the proposals in the panels may be transferred between panels.

·Ex-aequo Proposals

·When the total scores of two or more proposals are equal (ex-aequo cases), the priority order will be established as follows:

1.The proposals will be prioritised according to the scores they have been awarded for the criterion ‘Excellence’. When these scores are equal, priority will be based on scores for the criterion ‘Impact’.

2.If necessary, the gender balance among the supervisors named in the proposal will be used as a factor for prioritisation.

3.If a distinction still cannot be made, the panel may decide to further prioritise by considering other factors such as environmental considerations in line with the MSCA Green Charter, gender and other diversity aspects in the research activities, participation of the non-academic sector (including involvement of SMEs), geographical diversity 81 , international cooperation, favourable employment and working conditions or relationship to the Horizon Europe objectives in general. These factors will be documented in the panel report.

1.6.Legal and financial set-up of the Grant Agreements

The following exceptions and additional conditions apply:

·Eligible costs must take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

·When associated partners are involved, beneficiaries are encouraged to sign a partnership agreement with them to regulate the internal relationship between all participating organisations. The partnership agreement(s) must comply with the grant agreement.

·Beneficiaries must ensure full access — on a royalty-free basis — for the recruited researchers to background and results needed for their activities under the action.

·The following deliverables will have to be submitted for grants awarded under this topic:

-establishment of a supervisory board of the network;

-progress report submitted within 30 days after one year from the starting date of the action;

-mid-term meeting organised between the participants and the granting authority;

-mobility declaration submitted within 20 days after the recruitment of each researcher and updated (if needed) via the Funding & Tenders Portal Continuous Reporting tool;

-career development plan: a document describing how the individual Career Development Plans have been established (listing also the researchers for whom such plans have been put in place), submitted before the mid-term meeting; 

-evaluation questionnaire completed by each recruited researcher and submitted at the end of the research training activity; a follow-up questionnaire submitted two years later;

-data management plan submitted at mid-term and an update towards the end of the project if needed;

-plan for the dissemination and exploitation of results, including communication activities, submitted at mid-term and an update towards the end of the project.

2.MSCA POSTDOCTORAL FELLOWSHIPS

2.1.Applicable unit contributions

The EU contribution for MSCA Postdoctoral Fellowships will take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme 82 .

The following budget categories apply:

MSCA Postdoctoral Fellowships

Contributions for the recruited researcher

per person-month

Institutional unit contributions

per person-month

Living allowance

Mobility allowance

Family allowance (if applicable)

Long-term leave allowance (if applicable)

Special needs allowance (if applicable)

Research, training and networking contribution

Management and indirect contribution

EUR 6350

EUR 710

EUR 660

EUR 7060 x % covered by the beneficiary

requested unit 83

x (1/number of months)

EUR 1000

EUR 650

A country correction coefficient applies to the living allowance in order to ensure equal treatment and purchasing power parity for all researchers 84 . For European Postdoctoral Fellowships, this coefficient is the one applicable to the country of the beneficiary. For the Global Postdoctoral Fellowships two different country correction coefficients apply:

-For the outgoing phase: the coefficient of the country where the postdoctoral researcher is hosted (i.e. the country of the associated partner hosting the outgoing phase);

-For the return phase: the coefficient of the country where the postdoctoral researcher returns to (i.e. the country of the beneficiary).

The country correction coefficients are listed in Table 1 at the end of this Work Programme part. The living allowance is a gross amount, including compulsory deductions under national law, such as employer and employee social security contributions and direct taxes.

The beneficiary must recruit the postdoctoral researcher under an employment contract or equivalent direct contract, including an instrument of appointment (e.g., for permanent staff and/or officials), with full social security coverage (including sickness, parental, unemployment and invalidity benefits, pension rights, benefits in respect of accidents at work and occupational diseases). An exemption from this rule can be accepted only in cases where national legislation or the equivalent internal regulations of International European Research Organisations (IERO), entities created under Union law, or an international organisation, prohibit this possibility and subject to the prior agreement of the granting authority.

When an employment contract or instrument of appointment cannot be provided, the beneficiary may exceptionally recruit the postdoctoral researcher under a 'fixed-amount fellowship'. In this case, the living allowance will be halved, and the beneficiary must ensure that the postdoctoral researcher enjoys minimum social security coverage (including sickness, parental and invalidity benefits, and benefits for accidents at work and occupational diseases).

The beneficiary must pay to the postdoctoral researcher at least the amount of the living allowance (minus all compulsory deductions under national legislation). A top-up may be paid to the researcher in order to complement this contribution. In addition to the living allowance, the postdoctoral researcher must receive a mobility allowance. This allowance covers their additional, private mobility-related costs (e.g. travel and accommodation costs), not professional costs under the action, which are covered by the research, training and networking contribution.

If the postdoctoral researcher has or acquires family obligations during the action duration, i.e. has persons linked to them by (i) marriage, or (ii) a relationship with equivalent status to a marriage recognised by the legislation of the country or region where this relationship was formalised; or (iii) dependent children who are actually being maintained by the researcher, the family allowance must be paid to them as well.

The long-term leave allowance contributes to the personnel costs incurred by the beneficiary in case of the researcher’s leave, including maternity, paternity, parental, sick or special leave, longer than 30 consecutive days. The special needs allowance contributes to the additional costs for the acquisition of special needs items and services for researchers with disabilities, whose long-term physical, mental, intellectual or sensory impairments 85 are certified by a competent national authority, and of such nature that their participation in the action may not be possible without them (e.g. assistance by third persons, adaptation of work environment, additional travel/transportation costs). These special needs items or services must not have been funded from another source (e.g. social security or health insurance). Both long-term leave and special needs allowances should be requested when the need arises. 

The research, training and networking contribution should cover, for example, costs for training and networking activities that contribute directly to the researchers’ career development (e.g. participation in conferences, trips related to work on the action, training, language courses, seminars, lab material, books, library records, publication costs), research expenses, visa-related fees and travel expenses, additional costs arising from optional secondments (e.g. travel and accommodation costs).

The management and indirect contribution should cover the beneficiary’s additional costs in connection with the action (e.g. personnel costs for project management, indirect costs).

The above rates apply to postdoctoral researchers devoting themselves to their project on a full-time basis. Researchers may, in agreement with the supervisor and beneficiary and with prior approval by the granting authority, implement their project on a part-time basis. In addition to the possibility to request part-time work for personal or family reasons, postdoctoral fellows may opt to work part-time for professional reasons. These might include creating a company, pursuing another research project 86 , or engaging in advanced studies not related to the MSCA grant. Part-time work for professional reasons is not allowed during the outgoing phase of the Global Postdoctoral Fellowships. Any professional activities carried out part-time in parallel with the MSCA action must be agreed upon by the researcher and the beneficiary and approved by the granting authority.

If the action is implemented on a part-time basis, the researcher must dedicate at least 50% of their working time to the action funded by the MSCA 87 . The beneficiary should report costs as pro rata of the applicable full-time unit contributions.

2.2.Admissibility

The following exceptions to the General Annex A apply:

·The page limit of the application is 10 pages (excluding annexes). 

2.3.Eligibility

Given the specific nature of MSCA Postdoctoral Fellowships, the following exceptions and additional eligibility criteria apply. This section also contains eligibility conditions for unit contributions, which apply during action implementation but cannot be verified at proposal stage.

·All domains of research and technological development are eligible for funding (including areas of research covered by the Euratom Research and Training Programme).

·Proposals involving the same recruiting organisation (and for Global Postdoctoral Fellowships also the associated partner hosting the outgoing phase) and individual researcher submitted to the previous call of MSCA Postdoctoral Fellowships under Horizon Europe and having received a score of less than 80% must not be resubmitted the following year.

·Only one proposal per individual researcher can be submitted. In case of several proposals involving the same individual researcher, only the last submitted one will be considered eligible.

·If proposals with the same research objectives and work plan are submitted for different researchers, only the first submitted one will be considered eligible.

2.3.1.Participating organisations

·Applications must be submitted by a single independent legal entity, established in an EU Member State or Horizon Europe Associated Country. This is a mono-beneficiary action.

·The associated partner hosting the outgoing phase in Global Postdoctoral Fellowships must include a letter of commitment in the proposal to ensure their active participation in the action.

·Applications in the research areas of research covered by the Euratom Research and Training Programme must be submitted by a single independent legal entity, established in an EU Member State or a country associated to the Euratom Research and Training Programme. Nuclear-related proposals submitted by entities established in other countries will be ineligible 88 .

·Affiliated entities are not allowed to participate as they cannot claim costs in MSCA Postdoctoral Fellowships.

·International organisations with headquarters in an EU Member State or Horizon Europe Associated Country will be deemed to be established in this Member State or Associated Country.

·The beneficiary must employ and supervise the researcher during the action 89 .

·Eligibility to participate is also subject to the ‘Restrictions for the protection of European communication networks’ and ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility conditions (see General Annex B of the General Annexes).

2.3.2.Recruited researchers

·Supported fellows must be postdoctoral researchers at the date of the call deadline, i.e. in a possession of a doctoral degree 90 . Applicants who have successfully defended their doctoral thesis but who have not yet formally been awarded the doctoral degree will also be considered as postdoctoral researchers and will be considered eligible to apply. The successful defence must be unconditional (no further requirements/corrections that need to be addressed) and take place before the call deadline. Supporting documentation may be requested.

·At the call deadline, supported researchers must have a maximum of 8 years full-time equivalent experience in research, measured from the date of award of the doctoral degree. Years of experience outside research and career breaks (e.g. due to parental leave 91 ), will not count towards the amount of research experience. For nationals or long-term residents of EU Member States or Horizon Europe Associated Countries who wish to reintegrate to pursue their research career in EU Member States or Horizon Europe Associated Countries, years of experience in research in third countries will not be considered in the above maximum.

·Recruited researchers must comply with the following mobility rule: they must not have resided or carried out their main activity 92 (work, studies, etc.) in the country of the beneficiary (for European Postdoctoral Fellowships), or the host organisation for the outgoing phase (for Global Postdoctoral Fellowships) for more than 12 months in the 36 months immediately before the call deadline.

Researchers wishing to reintegrate from a third country must either be based in a third country at the call deadline or have moved directly from a third country to an EU Member State or Horizon Europe Associated Country within the last 12 months before the call deadline.

For 'International European Research Organisations' (IERO), 'international organisations', or entities created under Union law, the researchers must not have spent more than 12 months in the 36 months immediately before the call deadline, in the same appointing organisation.

·Compulsory national service, short stays such as holidays, time spent by the researcher as part of a procedure for obtaining refugee status under the Geneva Convention 93 and time spent for obtaining EU temporary protection 94 are not taken into account.

·Researchers who, at the date of the call deadline have refugee status under the Geneva Convention, or benefit from the EU temporary protection are exempt from the mobility rule.

·Supported researchers can be of any nationality. However, researchers going to a third country (‘Global Postdoctoral Fellowship) or researchers who wish to reintegrate to Europe (i.e. in an EU Member State or Horizon Europe Associated Country), must be nationals or long-term residents of EU Member States or Horizon Europe Associated Countries. Long-term residence means a period of legal and continuous residence within EU Member States or Horizon Europe Associated Countries of at least five consecutive years. Absences of less than six consecutive months and no more than ten months over the whole period are permitted when calculating the five years.

Researchers who are refugees in an EU Member State or Horizon Europe Associated Country according to the Geneva Convention or beneficiaries of EU temporary protection 95 may also apply to both European and Global Postdoctoral Fellowships, irrespective of whether they are long-term residents or not, if they fulfil the other eligibility conditions.

·Applicants in the research areas covered by the Euratom Research and Training Programme must recruit nationals or long-term residents of an EU Member State or a country associated to the Euratom Research and Training Programme.

2.3.3.Duration of the action

·European Postdoctoral Fellowships should last between 12 and 24 months. Global Postdoctoral Fellowships should last between 24 and 36 months, consisting of 12 to 24 months for the outgoing phase and 12 months for the return phase.

·If requested and justified in the proposal, an additional period of up to six months at the end of the project can be awarded to researchers who will spend that period in a non-academic organisation established in an EU Member State or Horizon Europe Associated Country.

2.4.Award criteria

·Proposals will be evaluated by experts on the basis of the award criteria 'excellence', 'impact' and 'quality and efficiency of the implementation'.

·Evaluation scores will be awarded for each of these criteria, and not for the different aspects listed in the table below. Each criterion will be scored out of 5. Scores will be awarded with a resolution of one decimal place and will be subject to a weighting factor as indicated in the table below.

·The threshold for all criteria (Excellence, Impact and Implementation) will be 3.

·Proposals scoring equal to or above 70% will be considered for funding — within the limits of the available call budget. Other proposals will be rejected.

Excellence

Impact

Quality and efficiency
of the implementation

Quality and pertinence of the project’s research and innovation objectives (and the extent to which they are ambitious, and go beyond the state of the art)

Credibility of the measures to enhance the career perspectives and employability of the researcher and contribution to their skills development

Quality and effectiveness of the work plan, assessment of risks and appropriateness of the effort assigned to work packages 

Soundness of the proposed methodology (including interdisciplinary approaches, consideration of the gender dimension and other diversity aspects if relevant for the research project, and the quality of open science practices)

Suitability and quality of the measures to maximise expected outcomes and impacts, as set out in the dissemination and exploitation plan, including communication activities

Quality and capacity of the host institutions and participating organisations, including hosting arrangements

Quality of the supervision, training and of the two-way transfer of knowledge between the researcher and the host

The magnitude and importance of the project’s contribution to the expected scientific, societal and economic impacts

Quality and appropriateness of the researcher’s professional experience, competences and skills

50%

30%

20%

Weighting

2.5.Procedure

·In Postdoctoral Fellowships, proposals will be evaluated by one of eight 'main evaluation panels': Chemistry (CHE), Social Sciences and Humanities (SOC), Economic Sciences (ECO), Information Science and Engineering (ENG), Environment and Geosciences (ENV), Life Sciences (LIF), Mathematics (MAT), Physics (PHY). Each panel will establish two ranked lists, one for European and one for Global Postdoctoral Fellowships.

·European and Global Postdoctoral Fellowships will have separate budgets. The distribution of respective available funds will be proportional to the number of eligible proposals received in each main evaluation panel. If the budget allocated to any panel exceeds the requirements of all proposals positively evaluated 96 in that panel, the excess budget will be reallocated to the other panels based on the distribution as above. Equally, if the allocated funding to a panel is insufficient to fund the highest ranked proposal in that panel, the necessary budget will be transferred from the other panels based on the distribution as above, in order to ensure that the highest ranked proposal can be funded. In order to ensure budget optimisation and an equitable success rate across panels, the excess budget remaining after the initial allocation of funding to the proposals in the panels may be transferred between panels.

Ex-aequo Proposals

·When the total scores of two or more proposals are equal (ex-aequo cases), the priority order will be established as follows:

1. The proposals will be prioritised according to the scores they have been awarded for the criterion ‘Excellence’. When these scores are equal, priority will be based on scores for the criterion ‘Impact’.

2.If necessary, the gender balance among successful applicant researchers will be used as a factor for prioritisation.

If a distinction still cannot be made, the panel may decide to further prioritise by considering other factors such as environmental considerations in line with the MSCA Green Charter, gender and other diversity aspects in the research activities, participation of the non-academic sector (including involvement of SMEs), geographical diversity 97 , favourable employment and working conditions or relationship to the Horizon Europe objectives in general. These factors will be documented in the panel report.

Seal of Excellence

·Seals of Excellence will be awarded to applications with a total score equal to or higher than 85%, but which cannot be funded due to lack of budget available to the call.

2.6.Legal and Financial set-up of the Grant Agreements

The following exceptions and additional conditions apply:

·Eligible costs must take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

·When associated partners are involved, the beneficiary is encouraged to sign a partnership agreement with them to regulate the internal relationship between all participating organisations. The partnership agreement(s) must comply with the grant agreement.

·The beneficiary must ensure full access — on a royalty-free basis — for the recruited researcher to background and results needed for their activities under the action.

·The following deliverables will have to be submitted for grants awarded under this topic:

-mobility declaration submitted within 20 days of the start of the research training activities and updated (if needed) via the Funding & Tenders Portal Continuous Reporting tool;

-career development plan of the recruited researcher, submitted at the beginning of the action (not later than 6 months after its start) and updated if needed throughout the project;

-evaluation questionnaire completed by the recruited researcher and submitted at the end of the research training activity; a follow-up questionnaire submitted two years later;

-data management plan submitted within the first 6 months of the project;

-plan for the dissemination and exploitation of results submitted towards the end of the project.

3.MSCA STAFF EXCHANGES

3.1.Applicable unit contributions

The EU contribution for MSCA Staff Exchanges will take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme 98 .

The following budget categories apply:



MSCA Staff Exchanges

Contributions for seconded staff members

per person-month

Institutional contributions

per person-month

Top-up allowance

Special needs allowance (if applicable)

Research, training and networking contribution

Management and indirect contribution

EUR 2870

requested unit 99

x (1/number of months)

EUR 1300

EUR 1000

The top-up allowance for the seconded staff member contributes to travel, accommodation and subsistence costs related to the secondment.

The special needs allowance contributes to the additional costs for the acquisition of special needs items and services for staff members with disabilities, whose long-term physical, mental, intellectual or sensory impairments 100 are certified by a competent national authority, and of such nature that their participation in the action may not be possible without them (e.g. assistance by third persons, adaptation of work environment, additional travel/transportation costs). These special needs items or services must not have been funded from another source (e.g. social security or health insurance). The special needs allowance should be requested when the need arises. 

The research, training and networking contribution should cover costs for training, transfer of knowledge and networking activities, as well as research expenses.

The management and indirect contribution should cover the beneficiary’s additional costs in connection with the action (e.g. personnel costs for project management/coordination, indirect costs).

3.2.Admissibility

The following exception to the General Annex A applies:

·The page limit of the application is 30 pages (excluding annexes).

3.3.Eligibility

Given the specific nature of MSCA Staff Exchanges, the following exceptions and additional eligibility criteria apply. This section also contains eligibility conditions for unit contributions, which apply during action implementation but cannot be verified at proposal stage.

3.3.1.Participating organisations

·Applications must be submitted by a consortium including at least three independent legal entities in three different countries, two of which established in a different EU Member State or Horizon Europe Associated Country.

·The consortium must include participating organisations from both academic and non-academic sectors.

·International organisations with headquarters in an EU Member State or Horizon Europe Associated Country will be deemed to be established in this Member State or Associated Country.

·The European Commission Joint Research Centre (JRC) may participate as member of the consortium selected for funding. 

·Affiliated entities are not allowed to participate as they cannot claim costs in MSCA Staff Exchanges.

·Only legal entities that are established in EU Member States or Horizon Europe Associated Countries can be beneficiaries.

·For secondments from associated partners linked to a beneficiary, only the sector (academic or non-academic) of the beneficiary counts; the linked associated partners will be considered to belong to the same sector as their beneficiary.

·Secondments must be between different countries 101 ; secondments between non-associated third countries are not eligible. 102

·Secondments must be performed on a full-time basis102.

·Eligibility to participate is also subject to the ‘Restrictions for the protection of European communication networks’ and ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility conditions (see General Annex B of the General Annexes).

3.3.2.Seconded staff members

·Secondments are open for researchers at any career stage (from doctoral candidates to postdoctoral researchers 103 ), as well as administrative, managerial and technical staff supporting R&I activities under the action.102 

·After the period of secondment, seconded staff should return to their sending institution, thus maximising the impact of the action for knowledge sharing and long-term collaboration.102

3.3.3.Duration of the action

·The maximum duration of the project is 48 months from the starting date set out in the grant agreement. 

·The overall EU contribution for MSCA Staff Exchanges amounts to a maximum of 360 person-months per project.

·Secondments must last at least one month and cannot be longer than 12 months for the same staff member (independently of the number of organisations the staff is seconded to).102 

·The secondment of a staff member may be split into several stays with one or several beneficiaries or associated partners.102 

·Secondments beyond the project duration cannot be funded.

3.4.Award criteria 

·Proposals will be evaluated by experts on the basis of the award criteria 'excellence', 'impact' and 'quality and efficiency of the implementation'.

·Evaluation scores will be awarded for each of these criteria, and not for the different aspects listed in the table below. Each criterion will be scored out of 5. Scores will be awarded with a resolution of one decimal place and will be subject to a weighting factor as indicated in the table below.

·The threshold for all criteria (Excellence, Impact and Implementation) will be 3.

·Proposals scoring equal to or above 70% will be considered for funding — within the limits of the available call budget. Other proposals will be rejected.

Excellence

Impact

Quality and efficiency
of the implementation

Quality and pertinence of the project’s research/innovation objectives (and the extent to which they are ambitious, and go beyond the state of the art)

Developing new and lasting research collaborations, achieving transfer of knowledge between participating organisations and contributing to improving research and innovation potential at the European and global level

Quality and effectiveness of the work plan, assessment of risks, and appropriateness of the effort assigned to work packages 

Soundness of the proposed approach to foster international, intersectoral and interdisciplinary collaborations

Credibility of the measures to enhance the career perspectives of staff members and contribution to their skills development

Quality, capacity and role of each participant, including hosting arrangements and extent to which the consortium as a whole brings together the necessary expertise 

Soundness of the proposed methodology (including consideration of the gender dimension and other diversity aspects if relevant for the research project, and the quality of open science practices)

Suitability and quality of the measures to maximise expected outcomes and impacts, as set out in the dissemination and exploitation plan, including communication activities

Quality of the proposed interaction between the participating organisations in light of the research and innovation objectives.

The magnitude and importance of the project’s contribution to the expected scientific, societal and economic impacts. 

50%

30%

20%

Weighting

3.5.Procedure

·Proposals will be evaluated by one of eight 'main evaluation panels': Chemistry (CHE), Social Sciences and Humanities (SOC), Economic Sciences (ECO), Information Science and Engineering (ENG), Environment and Geosciences (ENV), Life Sciences (LIF), Mathematics (MAT), Physics (PHY). Each panel establishes a ranked list.

·The distribution of the indicative budget of the call will be proportional to the number of eligible proposals received in each panel. If the budget allocated to any panel exceeds the requirements of all proposals positively evaluated 104 in that panel, the excess budget will be reallocated to the other panels based on the distribution as above. Equally, if the allocated funding to a panel is insufficient to fund the highest ranked proposal in that panel, the necessary budget will be transferred from the other panels based on the distribution as above, in order to ensure that the highest ranked proposal can be funded. In order to ensure budget optimisation and an equitable success rate across panels, the excess budget remaining after the initial allocation of funding to the proposals in the panels may be transferred between panels.

·Ex-aequo Proposals

·When the total scores of two or more proposals are equal (ex-aequo cases), the priority order will be established as follows:

1. The proposals will be prioritised according to the scores they have been awarded for the criterion ‘Excellence’. When these scores are equal, priority will be based on scores for the criterion ‘Impact’.

2.If a distinction still cannot be made, the panel may decide to further prioritise by considering other factors such as environmental considerations in line with the MSCA Green Charter, gender and other diversity aspects in the research activities, participation of the non-academic sector (including involvement of SMEs), geographical diversity 105 , international cooperation, favourable working/secondment conditions or relationship to the Horizon Europe objectives in general. These factors will be documented in the panel report. 

3.6.Legal and financial set-up of the Grant Agreements

The following exceptions and additional conditions apply:

·Eligible costs must take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

·When associated partners are involved, beneficiaries are encouraged to sign a partnership agreement with them to regulate the internal relationship between all participating organisations. The partnership agreement(s) must comply with the grant agreement.

·Grants awarded under this topic might be linked to other actions funded by Horizon 2020 or Horizon Europe.

·Beneficiaries must ensure full access — on a royalty-free basis — for the staff members to background and results needed for their activities under the action.

·The following deliverables will have to be submitted for grants awarded under this topic:

mid-term meeting organised between the participants and the granting authority;

progress report submitted within 30 days after one year from the starting date of the action;

mobility declaration submitted within 20 days of the secondment of each seconded staff member, and updated (if needed) via the Funding & Tenders Portal Continuous Reporting tool;

evaluation questionnaire completed by the seconded staff members and submitted at the end of their secondments; a follow-up questionnaire submitted two years later;

data management plan submitted at mid-term and an update towards the end of the project if needed;

plan for the dissemination and exploitation of results, including communication activities submitted at mid-term and an update towards the end of the project.

4.MSCA COFUND 106

4.1.Applicable unit contributions

The EU contribution for MSCA COFUND will take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme 107 .

The following budget categories apply:

MSCA COFUND

Contributions for recruited researchers and institutional contributions

per person-month

COFUND allowance

Long-term leave allowance (if applicable)

Special needs allowance (if applicable)

Doctoral programmes

EUR 3500

EUR 3500 x % covered by the beneficiary

requested unit 108

x (1/number of months)

Postdoctoral programmes

EUR 4980

EUR 4980 x % covered by the beneficiary

The COFUND allowance contributes to:

-costs of the researchers including the remuneration payable to the individual doctoral or postdoctoral researchers recruited under an employment contract/equivalent direct contract with full social security coverage and complying with the applicable social security legislation, as well as the mobility costs and, if applicable, the family costs, and/or

-costs related to the training, research expenses, transfer of knowledge and networking activities of researchers, costs of managing the action and indirect costs.

The long-term leave allowance contributes to the personnel costs incurred by the employer in case of the researchers’ leave, including maternity, paternity, parental, sick or special leave, longer than 30 consecutive days. The special needs allowance contributes to the additional costs for the acquisition of special needs items and services for researchers with disabilities, whose long-term physical, mental, intellectual or sensory impairments 109 are certified by a competent national authority, and of such nature that their participation in the action may not be possible without them (e.g. assistance by third persons, adaptation of work environment, additional travel/transportation costs). These special needs items or services must not have been funded from another source (e.g. social security or health insurance). Both long-term leave and special needs allowances should be requested when the need arises.

The beneficiary or implementing partner must recruit each eligible researcher under an employment contract or 'equivalent direct contract' with full social security coverage (including sickness, parental, unemployment and invalidity benefits, pension rights, benefits in respect of accidents at work and occupational diseases). An exemption from this rule can be accepted only in cases where national legislation or the equivalent internal regulations of International European Research Organisations (IERO), entities created under Union law, or an international organisation, prohibit this possibility and subject to the prior agreement of the granting authority.

When an employment contract cannot be provided, the beneficiary or the implementing partner may exceptionally recruit the researcher under a 'fixed-amount fellowship'. In this case, the COFUND allowance will be halved, and the beneficiary must ensure that the researcher enjoys minimum social security coverage (including sickness, parental and invalidity benefits, and benefits for accidents at work and occupational diseases).

In principle, researchers should be employed full-time. The above rates apply to researchers devoting themselves to their project on a full-time basis. Researchers may, in agreement with the supervisor and beneficiary and with prior approval by the granting authority, implement their project on a part-time basis. In addition to the possibility to request part-time work for personal or family reasons, postdoctoral fellows may opt to work part-time for professional reasons. These might include creating a company, pursuing another research project 110 , or engaging in advanced studies not related to the MSCA grant. Any professional activities carried out part-time in parallel with the MSCA action must be agreed upon by the researcher and the beneficiary and approved by the granting authority.

In cases of part-time work, researchers must work at least 50% of the full working time in their recruiting organisation for the action co-funded by the MSCA, whether they are working part-time for family or other reasons 111 . The beneficiary should report costs as pro rata of the applicable full-time unit contributions.

The EU contribution is limited to EUR 10 million per beneficiary per call. If an applicant submits two or more successful applications totalling more than EUR 10 million within one call, the applicant will be required to decide which of these proposals to implement.

The table above specifies the unit contributions for the co-funding of regional, national and international programmes. The EU contribution can be used to support any cost items of the programme (remuneration costs, mobility costs, family costs, research, training and networking costs, management and indirect costs). Individual cost items may be fully or partially funded through other resources including EU programmes other than Horizon 2020 or Horizon Europe, such as the Cohesion policy funds, provided that double funding is avoided.

Applicants must specify in their proposal the total cost of their proposed programme and in particular the amounts that will be provided for the benefit of the researchers and for the organisation(s) that will implement the programme. This information will be needed to evaluate the adequateness of employment and working conditions of the researchers. The monthly gross remuneration, i.e. salaries, social security contributions, taxes and other costs or compulsory deductions under national legislation linked to in the remuneration, and the mobility costs for the benefit of the researchers must be:

-For researchers recruited under an employment contract: not lower than EUR 3500 (for doctoral candidates) and EUR 4980 (for postdoctoral researchers);

-For researchers recruited under a fixed-amount fellowship: not lower than EUR 1750 (for doctoral candidates) and EUR 2490 (for postdoctoral researchers).

4.2.Admissibility

The following exceptions to the General Annex A apply:

·The page limit of the application is 30 pages (excluding annexes).

4.3.Eligibility

Given the specific nature of MSCA COFUND, the following exceptions and additional eligibility criteria apply. This section also contains eligibility conditions for unit contributions, which apply during action implementation but cannot be verified at proposal stage.

4.3.1.Participating organisations

·Applications must be submitted by a single entity established in an EU Member State or Horizon Europe Associated Country.

·Affiliated entities are not allowed to participate as they cannot claim costs in MSCA COFUND.

·The conditions for financial support to third parties defined in General Annex B do not apply.

·International organisations with headquarters in an EU Member State or Horizon Europe Associated Country will be deemed to be established in this Member State or Associated Country.

·The beneficiary will be responsible for the availability of the necessary complementary funds to implement the proposal.

·In each COFUND action, a minimum of three researchers must be recruited. COFUND proposals foreseeing research training for fewer than three researchers will be deemed ineligible.

·Implementing partners must be established in one of the countries eligible for funding listed in the General Annexes. 112

·Eligibility to participate is also subject to the ‘Restrictions for the protection of European communication networks’ and ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility conditions (see General Annex B of the General Annexes).

4.3.2.Recruited researchers 113

·Recruited researchers can be of any nationality (see also specific condition for COFUND postdoctoral programmes below) and must comply with the following mobility rule: they must not have resided or carried out their main activity 114 (work, studies, etc.) in the country of the recruiting beneficiary or implementing partner for more than 12 months in the 36 months immediately before the deadline of the co-funded programme's call.

For International European Research Organisations’ (IERO), 'international organisations' or entities created under Union law, the researchers must not have spent more than 12 months in the 36 months immediately before the deadline of the co-funded programme's call, in the same appointing organisation.

·Compulsory national service, short stays such as holidays, time spent by the researcher as part of a procedure for obtaining refugee status under the Geneva Convention 115 and time spent for obtaining EU temporary protection 116 are not taken into account.

·Researchers who, at the date of their recruitment date have refugee status under the Geneva Convention, or benefit from the EU temporary protection are exempt from the mobility rule.

·Supported researchers must be either doctoral candidates or postdoctoral researchers, depending on the action:

oFor COFUND doctoral programmes, researchers must be doctoral candidates, i.e. hold a degree which qualifies them for enrolment in a doctoral programme and not be already in possession 117 of a doctoral degree at the deadline of the co-funded programme's call.

Recruited researchers must be enrolled in a doctoral programme leading to the award of a doctoral degree in at least one EU Member State or Horizon Europe Associated Country.

oFor COFUND postdoctoral programmes, researchers must be in possession of a doctoral degree 118 at the deadline of the co-funded programme's call. Researchers who have successfully defended their doctoral thesis but who have not yet formally been awarded the doctoral degree will also be considered as postdoctoral researchers and will be considered eligible to apply. The successful defence must be unconditional (no further requirements/corrections that need to be addressed) and take place before the call deadline. Supporting documentation may be requested.

·For COFUND postdoctoral programmes: researchers must be nationals or long-term residents of an EU Member State or Horizon Europe Associated Country, in case the main part of the research training activities is carried out in a country other than an EU Member State or Horizon Europe Associated Country.

·Limitations regarding the researchers' origin and destination should be avoided. Researchers who are already permanently employed by the organisation hosting them cannot be funded by COFUND.

4.3.3.Duration of the action

·The maximum duration of the action must be 60 months from the starting date set out in the grant agreement. It also includes the time that is needed to select and recruit the researchers.

·The minimum duration of each fellowship (on the basis of full-time employment) must be three months.

·For postdoctoral programmes where the main part of the research training activity does not take place in an EU Member State or a Horizon Europe Associated Country (i.e. outgoing phase), the researcher should carry out a mandatory return period of 12 months at the premises of the beneficiary or the recruiting implementing partner. A maximum of three months can be spent at the start of the action at the beneficiary (or any other organisation mentioned in the description of the action), allowing the researcher to spend time there before the outgoing phase. Secondments cannot take place during the mandatory twelve-month return period to the host organisation in an EU Member State or Horizon Europe Associated Country.112

·The duration of the secondments should be limited to a maximum of half of the actual months spent implementing the research training activities under the action or, if applicable, of the duration of the outgoing phase for postdoctoral programmes.112

4.4.Award criteria 

·Proposals will be evaluated by experts on the basis of the award criteria 'excellence', 'impact' and 'quality and efficiency of the implementation'.

·Evaluation scores will be awarded for each of these criteria, and not for the different aspects listed in the table below. Each criterion will be scored out of 5. Scores will be awarded with a resolution of one decimal place and will be subject to a weighting factor as indicated in the table below.

·The threshold for all criteria (Excellence, Impact and Implementation) will be 3.

·Proposals scoring equal to or above 70% will be considered for funding — within the limits of the available call budget. Other proposals will be rejected.

Excellence

Impact

Quality and efficiency
of the implementation

Quality and pertinence of the programme’s research and innovation objectives (and the extent to which they are ambitious, and go beyond the state of the art) 

Strengthening human resources good practices at institutional, regional, national, or international level, in particular through aligning the practices of participating organisations with the principles set out by the EU for human resources development in research and innovation

Quality and effectiveness of the work plan, management structures, assessment of risks and appropriateness of the effort assigned to work packages 

Quality and novelty of the selection / recruitment process for the researchers (transparency, composition and organisation of selection committees, evaluation criteria, equal opportunities, the gender dimension and other diversity aspects) and quality and attractiveness of the appointment conditions, including competitiveness of the salary for the standards of the hosting countries

Credibility of the proposed measures to enhance the career perspectives and employability of researchers and contribution to their skills development

Quality and capacity of the host institution(s) and participating organisations (where appropriate), including hosting arrangements and extent to which they bring together the necessary expertise to successfully implement the research training programme 

Quality and novelty of the research options offered by the programme in terms of interdisciplinarity, inter-sectorality and level of international mobility. Quality of open science practices

Suitability and quality of the measures to maximise the expected outcomes and impacts, as set out in the dissemination and exploitation plan, including communication activities

Quality, novelty and pertinence of the research training programme (including transferable skills, inter/multidisciplinary, inter-sectoral and gender as well as other diversity aspects)

Quality, novelty and pertinence of the supervision, career guidance and career development arrangements

50%

30%

20%

Weighting

4.5.Procedure

·In 2026, the evaluation of the call HORIZON-MSCA-2026-COFUND-01 will be organised in two different panels, doctoral programmes and postdoctoral programmes, but a single ranking list will be produced.

·In 2027, the evaluation of the call HORIZON-MSCA-2027-COFUND-01 will be organised in a single panel, doctoral programmes.

Ex-aequo Proposals

·When the total scores of two or more proposals are equal (ex-aequo cases), the priority order will be established as follows:

The proposals will be prioritised according to the scores they have been awarded for the criterion ‘Excellence’. When these scores are equal, priority will be based on scores for the criterion ‘Impact’. If a distinction still cannot be made, the panel may decide to further prioritise by considering other factors such as environmental considerations in line with the MSCA Green Charter, gender and other diversity aspects in the research activities, participation of the non-academic sector (including involvement of SMEs), geographical diversity, synergies with Cohesion policy funds, support to Smart Specialisation Strategies, or relationship to the Horizon Europe objectives in general. These factors will be documented in the panel report.

Seal of Excellence

Seals of Excellence will be awarded to applications with a total score equal to or higher than 85%, but which cannot be funded due to lack of budget available to the call.

4.6.Legal and financial set-up of the Grant Agreements

The following exceptions and additional conditions apply:

·Eligible costs must take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

·When implementing partners are involved, the beneficiary should sign a partnership agreement with them to regulate the internal relationship between all participating organisations. The partnership agreement(s) must comply with the terms of the grant agreement.

·When associated partners are involved, the beneficiary is encouraged to sign a partnership agreement with them to regulate the internal relationship between all participating organisations. The partnership agreement(s) must comply with the terms of the grant agreement.The beneficiary may provide financial support to third parties. The support to third parties can only be provided in the form of grants, based on the MSCA unit contributions. Implementing partners are considered recipients of financial support to third parties.

·Grants awarded under this topic may be linked to actions funded under the Cohesion policy funds.

·The beneficiary must ensure full access — on a royalty-free basis — for the recruited researchers to background and results needed for their activities under the action.

·The following deliverables will have to be submitted for grants awarded under this topic:

mid-term meeting organised between the participants and the granting authority;

mobility declaration submitted within 20 days of the start of the research training activities, for each researcher, and updated (if needed) via the Funding & Tenders Portal Continuous Reporting tool;

-career development plan: a document describing how the individual Career Development Plans have been established (listing also the researchers for whom such plans have been put in place), submitted towards the end of the project; 

evaluation questionnaire completed by each recruited researcher and submitted at the end of the research training activity; a follow-up questionnaire submitted two years later;

data management plan submitted at mid-term and an update towards the end of the project if needed;

plan for the dissemination and exploitation of results, including communication activities submitted at mid-term and an update towards the end of the project.

5.MSCA CHOOSE EUROPE FOR SCIENCE

5.1.Applicable unit contributions

The EU contribution for MSCA Choose Europe for Science will take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme 119 .

The following budget categories apply:

MSCA Choose Europe for Science

Contributions for the recruited researcher

per person-month

(only applicable in the EU-funded phase)

Institutional unit contributions

per person-month

(only applicable in the EU-funded phase)

Living allowance

Mobility allowance

Family allowance (if applicable)

Long-term leave allowance (if applicable)

Special needs allowance (if applicable)

Research, training and networking contribution

Management and indirect contribution

EUR 6350

EUR 710

EUR 660

EUR 7060 x % covered by the beneficiary

requested unit 120

x (1/number of months)

EUR 1000

EUR 650

The monthly gross remuneration for the two phases 121 of each Choose Europe for Science programme, as well as the costs or compulsory deductions under national legislation, such as employer and employee social security contributions and direct taxes, must be clearly communicated in the vacancy notice.

Applicants must specify in their proposal the total cost of their proposed programme and in particular the amounts that will be provided for the benefit of the researchers in each phase. This information will be needed to evaluate the adequateness and attractiveness of employment and working conditions of the researchers.

The EU contribution is limited to EUR 5 million per beneficiary for this call. If an applicant submits two or more successful applications totalling more than EUR 5 million within this call, the applicant will be required to decide which of these proposals to implement.

Complementary funds to implement the project can be funded through other sources including EU programmes, such as the Cohesion policy funds, provided that double funding is avoided.

During both phases:

The beneficiary or implementing partner must recruit the researcher under an employment contract or equivalent direct contract, including an instrument of appointment (e.g., for permanent staff and/or officials), with full social security coverage (including sickness, parental, unemployment and invalidity benefits, pension rights, benefits in respect of accidents at work and occupational diseases). An exemption from this rule can be accepted only in cases where national legislation or the equivalent internal regulations of International European Research Organisations (IERO), entities created under Union law, or an international organisation, prohibit this possibility and subject to the prior agreement of the granting authority.

Both phases should contribute to the longer-term career prospects and employability of the recruited researcher after the project end.

During the EU-funded phase:

The beneficiary must pay to the researcher at least the amount of the living allowance (minus all compulsory deductions under national legislation). A top-up may be paid to the researcher in order to complement this contribution. In addition to the living allowance, the researcher must receive a mobility allowance. This allowance covers their additional, private mobility-related costs (e.g. travel and accommodation costs), not professional costs under the action, which are covered by the research, training and networking contribution.

A country correction coefficient applies to the living allowance in order to ensure equal treatment and purchasing power parity for all researchers 122 .

The country correction coefficients are listed in Table 1 at the end of this Work Programme part. The living allowance is a gross amount, including compulsory deductions under national law, such as employer and employee social security contributions and direct taxes.

If the researcher has or acquires family obligations during the action duration, i.e. has persons linked to them by (i) marriage, or (ii) a relationship with equivalent status to a marriage recognised by the legislation of the country or region where this relationship was formalised; or (iii) dependent children who are actually being maintained by the researcher, the family allowance must be paid to them as well.

The long-term leave allowance contributes to the personnel costs incurred by the beneficiary in case of the researcher’s leave, including maternity, paternity, parental, sick or special leave, longer than 30 consecutive days. The special needs allowance contributes to the additional costs for the acquisition of special needs items and services for researchers with disabilities, whose long-term physical, mental, intellectual or sensory impairments 123 are certified by a competent national authority, and of such nature that their participation in the action may not be possible without them (e.g. assistance by third persons, adaptation of work environment, additional travel/transportation costs). These special needs items or services must not have been funded from another source (e.g. social security or health insurance). Both long-term leave and special needs allowances should be requested when the need arises.

The research, training and networking contribution should cover, for example, costs for training and networking activities that contribute directly to the researchers’ career development (e.g. participation in conferences, trips related to work on the action, training, language courses, seminars, lab material, books, library records, publication costs), research expenses, visa-related fees and travel expenses, additional costs arising from optional secondments (e.g. travel and accommodation costs).

Researchers receiving a Choose Europe for Science Fellowship may opt to include a secondment phase, within the overall duration of their fellowship in any country worldwide. The secondment phase can be a single period or be divided into shorter mobility periods.

The secondments cannot exceed half of the requested duration of the action and should be in line with the project objectives, adding significant value and impact to the fellowship.

The management and indirect contribution should cover the beneficiary’s additional costs in connection with the action (e.g. personnel costs for project management, indirect costs).

The above rates apply to researchers devoting themselves to their project on a full-time basis. Researchers may, in agreement with the beneficiary and with prior approval by the granting authority, implement their project on a part-time basis. In addition to the possibility to request part-time work for personal or family reasons, researchers may opt to work part-time for professional reasons. These might include creating a company, pursuing another research project 124 , or engaging in advanced studies not related to the MSCA grant. Any professional activities carried out part-time in parallel with the MSCA action must be agreed upon by the researcher and the beneficiary and approved by the granting authority.

If the action is implemented on a part-time basis, the researcher must dedicate at least 50% of their working time to the action funded by the MSCA 125 . The beneficiary should report costs as pro rata of the applicable full-time unit contributions.

During the phase fully funded by the beneficiary:

The monthly gross remuneration can differ from the EU-funded phase but must remain attractive and competitive at national level. The beneficiary will be responsible for the availability of the necessary funds to cover all costs during this phase including the monthly gross remuneration and research, training and networking costs.

The beneficiary should follow the applicable national legislation regarding remuneration of researchers on leave and provisions for researchers with special needs.

5.2.Admissibility

The following exceptions to the General Annex A apply:

·The page limit of the application is 30 pages (excluding annexes).

·Applications do not need to include a plan for the exploitation and dissemination of results, including communication activities.

5.3.Eligibility

Given the specific nature of MSCA Choose Europe for Science, the following exceptions and additional eligibility criteria apply. This section also contains eligibility conditions for unit contributions, which apply during action implementation but cannot be verified at proposal stage.

5.3.1.Participating organisations

·Applications must be submitted by a single entity established in an EU Member State or Horizon Europe Associated Country.

·Affiliated entities are not allowed to participate as they cannot claim costs in MSCA Choose Europe for Science.

·International organisations with headquarters in an EU Member State or Horizon Europe Associated Country will be deemed to be established in this Member State or Associated Country.

·The beneficiary will be responsible for the availability of the necessary complementary funds to implement the proposal and ensure the coverage of the phase fully funded by the beneficiary as described in the proposal.

·In each Choose Europe for Science programme, a minimum of three researchers must be recruited. Proposals foreseeing recruitment for fewer than three researchers will be deemed ineligible.

·Implementing partners must be established in one of the countries eligible for funding listed in the General Annexes.

·When implementing partners are involved in an MSCA Choose Europe for Science programme, they must all be identified in the proposal.

·Eligibility to participate is also subject to the ‘Restrictions for the protection of European communication networks’ and ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility conditions (see General Annex B of the General Annexes).

5.3.2.Recruited researchers 126

·Recruited researchers can be of any nationality and must comply with the following mobility rule: they must not have resided or carried out their main activity (work, studies, etc.) in the country of the recruiting beneficiary or implementing partner for more than 12 months in the 36 months immediately before the deadline of the vacancy notice.

·For International European Research Organisations’ (IERO), 'international organisations' or entities created under Union law, the researchers must not have spent more than 12 months in the 36 months immediately before the deadline of the vacancy notice, in the same appointing organisation.

·Compulsory national service, short stays such as holidays, time spent by the researcher as part of a procedure for obtaining refugee status under the Geneva Convention 127 and time spent for obtaining EU temporary protection 128 are not taken into account.

·Researchers who, at the date of their recruitment date have refugee status under the Geneva Convention, or benefit from the EU temporary protection are exempt from the mobility rule.

·Researchers who are already permanently employed by the organisation hosting them cannot be funded by MSCA Choose Europe for Science.

·Researchers who are temporarily employed by the organisation hosting them and who adhere to the mobility requirement can be funded under MSCA Choose Europe for Science.

·Researchers must be nationals or long-term residents of an EU Member State or Horizon Europe Associated Country in case the main part of the activities is carried out in a country other than an EU Member State or Horizon Europe Associated Country.

·Limitations regarding the researchers' origin and destination should be avoided.

·Supported researchers must be in possession of a doctoral degree at the vacancy notice deadline. 129

5.3.3.Duration of the action

·The maximum duration of the action must be 60 months from the starting date set out in the grant agreement for a 48-month fellowship and 72 months for a 60-month fellowship. It also includes the time that is needed to select and recruit the researchers.

·Researchers must be recruited within the first 12 months of the action duration. 130

5.4.Award criteria 

·Proposals will be evaluated by experts on the basis of the award criteria 'excellence', 'impact' and 'quality and efficiency of the implementation'.

·Evaluation scores will be awarded for each of these criteria, and not for the different aspects listed in the table below. Each criterion will be scored out of 5. Scores will be awarded with a resolution of one decimal place and will be subject to a weighting factor as indicated in the table below.

·The threshold for all criteria (Excellence, Impact and Implementation) will be 3.

·Proposals scoring equal to or above 70% will be considered for funding — within the limits of the available call budget. Other proposals will be rejected.

Excellence

Impact

Quality and efficiency
of the implementation

Quality of the selection / recruitment process for the researchers (transparency, composition and organisation of selection committees, evaluation criteria, equal opportunities, the gender dimension and other diversity aspects)

Contribution to addressing local human resource needs, to advancing regional/national specialisation strategies, and to strengthening European research, innovation and teaching capacity

Quality, credibility and effectiveness of the recruitment plan, assessment of risks and appropriateness of the effort assigned towards offering concrete career prospects for recruited researchers

Quality and attractiveness of the appointment conditions, including inclusive working conditions, quality and attractiveness of the research environment and the resources, training and career development opportunities provided throughout the project, and the competitiveness of remuneration rates for the standards of the hosting countries offered in the phase of the fellowship fully funded by the beneficiary.

Strengthening human resources good practices at institutional, regional, national, or international level, in particular through aligning the practices of participating organisations with the principles set out by the EU for human resources development in research and innovation

Quality and capacity of the recruiting institutions, including hosting arrangements and alignment of institutional procedures with the European Charter for Researchers (institutions with the HRS4R label are exempted from providing further justification for this criterion) and the Agreement on Reforming Research Assessment

Quality and attractiveness of the concrete long-term career prospects that extend beyond the duration of the fellowship

Quality and ambition of the research, innovation and/or academic objectives of the programme

50%

30%

20%

Weighting

5.5.Procedure

·For MSCA Choose Europe for Science, the evaluation will be organised in a single panel.

Ex-aequo Proposals

·When the total scores of two or more proposals are equal (ex-aequo cases), the priority order will be established as follows:

The proposals will be prioritised first according to the scores they have been awarded for the criterion ‘Excellence’ and if these scores are equal, priority will be based on scores for the criterion ‘Impact’. When these scores are equal, priority will be based specifically on the career prospects offered to the recruited researchers. If a distinction still cannot be made, the panel may decide to further prioritise by considering geographical diversity. This will be documented in the panel report.

Seal of Excellence

Seals of Excellence will be awarded to applications with a total score equal to or higher than 85%, but which cannot be funded due to lack of budget available to the call.

5.6.Legal and financial set-up of the Grant Agreements

The following exceptions and additional conditions apply:

·Each Choose Europe for Science programme is made up of an EU-funded phase of 24 months for a 48-month fellowship or 36 months for a 60-month fellowship, and a phase fully covered by the beneficiary of 24 months.

·The minimum duration of each fellowship (on the basis of full-time employment) must be 48 months 131 and the maximum duration is 60 months 132 .

·Eligible costs must take the form of unit contributions, as stipulated in Decision of 11 March 2021 authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

·When implementing partners are involved, the beneficiary should sign a partnership agreement with them to regulate the internal relationship between all participating organisations. The partnership agreement(s) must comply with the grant agreement.

·When associated partners are involved, the beneficiary is encouraged to sign a partnership agreement with them to regulate the internal relationship between all participating organisations. The partnership agreement(s) must comply with the grant agreement.

·The beneficiary may provide financial support to third parties. The support to third parties can only be provided in the form of grants, based on the MSCA unit contributions. Implementing partners are considered recipients of financial support to third parties.

·Grants awarded under this topic may be linked to actions funded under the Cohesion policy funds.

·The beneficiary must ensure full access — on a royalty-free basis — for the recruited researchers to background and results needed for their activities under the action.

·The following deliverables will have to be submitted for grants awarded under this topic:

mid-term meeting organised between the participants and the granting authority;

-career development plan: a document describing how the individual Career Development Plans have been established (listing also the researchers for whom such plans have been put in place), submitted towards the end of the project;

evaluation questionnaire completed by each recruited researcher and submitted at the end of the research training activity; a follow-up questionnaire submitted two years later;

data management plan submitted at mid-term and an update towards the end of the project if needed.

Table 1: Country correction coefficients (CCC) for Doctoral Networks and Postdoctoral Fellowships living allowances    
For countries where the correction coefficient is not indicated, the Commission will decide on a case-by-case basis.

Country Code 133

CCC

EU Member States

AT

109,4%

BE

100%

BG

70%

CY

81,2%

CZ

97,4%

DE

101,5%

DK

131,3%

EE

95,2%

EL

87,7%

ES

94,2%

FI

116,4%

FR

116,6%

HR

82,2%

HU

78,7%

IE

135,8%

IT

93.8%

LT

89,8%

LU

100%

LV

85,6%

MT

91,8%

NL

111,8%

PL

77,5%

PT

94,6%

RO

72,6%

SE

119,3%

SI

88%

SK

82,9%

Third Countries

AE

106,6%

AL

70%

AM

120,7%

AO

145%

AR

86,9%

AU

102,8%

AZ

104,7%

BA

70%

BB

123,8%

BD

85%

BF

90,8%

BI

87,9%

BJ

97,3%

BO

79,1%

BR

101,7%

BQ

111,8%

BW

70,3%

BZ

79,9%

CA

105,9%

CD

142,2%

CF

102,2%

CG

137,3%

CH

163,7%

CI

87,3%

CL

77,5%

CM

91,4%

CN

88,3%

CO

78,9%

CR

91,4%

CU

160,7%

CV

70%

DJ

107,3%

DO

76,8%

DZ

70%

EC

85,9%

EG

70%

ER

110,8%

ET

93,7%

FJ

79,2%

FO

131,3%

GA

109,1%

GE

84%

GH

76,6%

GL

131,3%

GM

94,2%

GN

129,4%

GT

101%

GW

87,6%

GY

97,5%

HK

117,7%

HN

89,7%

HT

130,3%

ID

70%

IL

109,8%

IM

143,5%

IN

95,2%

IS

137,4%

JM

117,5%

JO

93,7%

JP

146,6%

KE

93,8%

KG

87,7%

KH

89,2%

KM

75,7%

KR

117,2%

KZ

86,7%

LA

70%

LB

116,2%

LI

163,7%

LK

82,2%

LR

132%

LS

70%

MA

79,7%

MD

91,6%

ME

70%

MG

85,5%

MK

70%

ML

94,5%

MM

70%

MR

96,4%

MU

74,8%

MV

95.2%

MW

70%

MX

77,5%

MY

77,8%

MZ

111,4%

NA

71,2%

NC

95%

NE

89,1%

NG

70%

NI

89,8%

NO

127%

NP

71,3%

NZ

94,8%

PA

104,9%

PE

92,3%

PF

116,6%

PG

97,4%

PH

85,5%

PK

70%

PS

109,8%

PY

70%

QA

115,4%

RS

74,5%

RW

87,7%

SA

97,9%

SB

112,7%

SD

89%

SG

124,5%

SL

95,5%

SN

85,2%

SR

70%

ST

106,4%

SV

86,4%

SZ

70%

TD

102,8%

TG

96,9%

TH

78%

TJ

74,3%

TL

86,5 %

TM

150,5%

TN

76,4%

TR

70%

TT

100,6%

TW

78,9%

TZ

94,9%

UA

80,2%

UG

87,1%

UK

143,5%

US

149,1%

UY

98%

UZ

72%

VA

93,8%

VN

71,2%

VU

104,8%

WS

82,2%

XK

70%

ZA

70%

ZM

90,7%

ZW

98,3%

(1)    As an illustration, Eurodoc published a list of such transferable skills at: http://eurodoc.net/skills-report-2018.pdf ; see also the European Competence Framework for Researchers, ResearchComp at: ec_rtd_research-competence-presentation.pdf (europa.eu)
(2)     http://www.geant.org
(3)    The term ‘researcher at risk’ refers to researchers at all stages of their career who are experiencing threats to their life, liberty, or research career, and those who are forced or have been forced to flee because of such threats.
(4)     https://ec.europa.eu/msca/supervision . While the Guidelines for MSCA supervision are non-binding, funded-projects are strongly encouraged to take them into account.
(5)    FAIR = Findable, Accessible, Interoperable, Reusable.
(6)     agreement_final.pdf (coara.eu)
(7)     https://ec.europa.eu/msca/green_charter . While the MSCA Green Charter is non-binding, funded projects are strongly encouraged to take into account the principles it sets out.
(8)    “Synergies between Horizon Europe and ERDF programmes (Draft Commission Notice)” C(2022) 4747 final. https://ec.europa.eu/regional_policy/en/information/publications/communications/2022/synergies-between-erdf-programmes-and-horizon-europe
(9)    The Recovery and Resilience Facility supports reforms and investments undertaken by Member States. The aim is to mitigate the economic and social impact of the coronavirus pandemic and make European economies and societies more sustainable, resilient and better prepared for the challenges and opportunities of the green and digital transitions.
(10)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/seal-excellence/funding-opportunities-under-msca_en
(11)    See particularly “Next generation Innovation Talents” under “Other actions” of the 2023 Work Programme of the EIC.
(12)    “Synergies between the Marie Skłodowska-Curie actions and the European Institute of Innovation and Technology”. https://op.europa.eu/en/publication-detail/-/publication/40f1a820-2cc2-11ed-975d-01aa75ed71a1/language-en
(13)    “Synergies between the Marie Skłodowska-Curie Actions and Erasmus+ in the area of higher education”. https://op.europa.eu/en/publication-detail/-/publication/f4d7d733-19ba-11ec-b4fe-01aa75ed71a1/language-en/
(14)    See definitions at the end of the Work Programme part
(15) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(16)     https://euraxess.ec.europa.eu/
(17)    Every time this Work Programme part refers to doctoral degrees, this means that the degrees have to be recognised as such by the relevant authorities of the country or countries concerned.
(18)     principles_for_innovative_doctoral_training.pdf
(19) For more guidance on specific areas of knowledge valorisation, see the European Commission’s Codes of Practice on intellectual assets management , on standardisation , on industry-academia co-creation and on citizen engagement for knowledge valorisation    “Knowledge valorisation” is the process of creating social and economic value from knowledge by linking different areas and sectors and by transforming data, know-how and research results into sustainable products, services, solutions and knowledge-based policies that benefit society” ( EUR-Lex - 32022H2415 - EN - EUR-Lex ).
(20) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(21)     https://euraxess.ec.europa.eu/
(22)    Every time this Work Programme part refers to doctoral degrees, this means that the degrees have to be recognised as such by the relevant authorities of the country or countries concerned.
(23)     principles_for_innovative_doctoral_training.pdf
(24) For more guidance on specific areas of knowledge valorisation, see the European Commission’s Codes of Practice on intellectual assets management , on standardisation , on industry-academia co-creation and on citizen engagement for knowledge valorisation    “Knowledge valorisation” is the process of creating social and economic value from knowledge by linking different areas and sectors and by transforming data, know-how and research results into sustainable products, services, solutions and knowledge-based policies that benefit society” ( EUR-Lex - 32022H2415 - EN - EUR-Lex ).
(25) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(26)    See eligibility conditions at the end of this Work Programme part.
(27)    See eligibility conditions at the end of this Work Programme part.
(28)    For proposals in the research areas covered by the Euratom Research and Training Programme, the organisation from the non-academic sector must be established in an EU Member State or a country associated to the Euratom Research and Training Programme
(29)    idem
(30) For more guidance on specific areas of knowledge valorisation, see the European Commission’s Codes of Practice on intellectual assets management , on standardisation , on industry-academia co-creation and on citizen engagement for knowledge valorisation    “Knowledge valorisation” is the process of creating social and economic value from knowledge by linking different areas and sectors and by transforming data, know-how and research results into sustainable products, services, solutions and knowledge-based policies that benefit society” ( EUR-Lex - 32022H2415 - EN - EUR-Lex ).
(31)    See eligibility conditions at the end of this Work Programme part
(32)    As indicated in the Euratom Work Programme
(33)    These countries are aligned with Work Programme part 11, Widening Participation and Strengthening the European Research Area
(34) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(35)    See eligibility conditions at the end of this Work Programme part.
(36)    See eligibility conditions at the end of this Work Programme part.
(37)    For proposals in the research areas covered by the Euratom Research and Training Programme, the organisation from the non-academic sector must be established in an EU Member State or a country associated to the Euratom Research and Training Programme
(38)    idem
(39) For more guidance on specific areas of knowledge valorisation, see the European Commission’s Codes of Practice on intellectual assets management , on standardisation , on industry-academia co-creation and on citizen engagement for knowledge valorisation    “Knowledge valorisation” is the process of creating social and economic value from knowledge by linking different areas and sectors and by transforming data, know-how and research results into sustainable products, services, solutions and knowledge-based policies that benefit society” ( EUR-Lex - 32022H2415 - EN - EUR-Lex ).
(40)    See eligibility conditions at the end of this Work Programme part
(41)    As indicated in the Euratom Work Programme
(42)    These countries are aligned with Work Programme part 11, Widening Participation and Strengthening the European Research Area
(43) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(44)    Virtual mobility is not allowed for secondments.
(45)    Interdisciplinarity means the integration of information, data, techniques, tools, perspectives, concepts or theories from two or more scientific disciplines (see definitions at the end of this Work Programme part).
(46) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(47)    Virtual mobility is not allowed for secondments.
(48)    Interdisciplinarity means the integration of information, data, techniques, tools, perspectives, concepts or theories from two or more scientific disciplines (see definitions at the end of this Work Programme part).
(49) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(50) For more guidance on specific areas of knowledge valorisation, see the European Commission’s Codes of Practice on intellectual assets management , on standardisation , on industry-academia co-creation and on citizen engagement for knowledge valorisation    “Knowledge valorisation” is the process of creating social and economic value from knowledge by linking different areas and sectors and by transforming data, know-how and research results into sustainable products, services, solutions and knowledge-based policies that benefit society” ( EUR-Lex - 32022H2415 - EN - EUR-Lex ).
(51)     https://euraxess.ec.europa.eu/
(52) For more guidance on specific areas of knowledge valorisation, see the European Commission’s Codes of Practice on intellectual assets management , on standardisation , on industry-academia co-creation and on citizen engagement for knowledge valorisation    “Knowledge valorisation” is the process of creating social and economic value from knowledge by linking different areas and sectors and by transforming data, know-how and research results into sustainable products, services, solutions and knowledge-based policies that benefit society” ( EUR-Lex - 32022H2415 - EN - EUR-Lex ).
(53) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(54) For more guidance on specific areas of knowledge valorisation, see the European Commission’s Codes of Practice on intellectual assets management , on standardisation , on industry-academia co-creation and on citizen engagement for knowledge valorisation    “Knowledge valorisation” is the process of creating social and economic value from knowledge by linking different areas and sectors and by transforming data, know-how and research results into sustainable products, services, solutions and knowledge-based policies that benefit society” ( EUR-Lex - 32022H2415 - EN - EUR-Lex ).
(55)     https://euraxess.ec.europa.eu/
(56) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(57)     Council Recommendation of 18 December 2023 on a European framework to attract and retain research, innovation and entrepreneurial talents in Europe
(58)     agreement_final.pdf (coara.eu)
(59)     EURAXESS |
(60) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(61)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(62)    See Article 1 of the UN Convention on the Rights of Persons with Disabilities.
(63)    See Article 5 of the Council Directive 2000/78/EC of 27 November 2000 establishing a general framework for equal treatment in employment and occupation.
(64) The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The budget figures given in this table are rounded to two decimal places.
(65)

     If requested by the granting authority, institutions with self-declared research organisations status must provide evidence that their main objective is to carry out research and/or technological development. An assessment will be made on the basis of indicators such as share of research budget, volume of scientific publications and/or registered patents.

(66)

   'International European Research Organisation' (IERO) means an international organisation, the majority of whose members are EU Member States or Horizon Europe Associated Countries, and whose principal objective is to promote scientific and technological cooperation in Europe (see Article 2(15) of the Regulation establishing Horizon Europe - the Framework Programme for Research and Innovation, laying down its rules for participation and dissemination.

(67)

     For Global Postdoctoral Fellowships and COFUND Postdoctoral Programmes outgoing phase, this restriction does not apply. The associated partner hosting the outgoing phase can conclude an additional employment contract with the researcher to ensure adequate medical/social insurance in the outgoing country.

(68)

     See specific conditions at the end of this Work Programme part.

(69)

      MSCA Keywords.pdf (europa.eu)

(70)

     The indicative budget includes budget provisions for the increase of the maximum EU contribution for grants funded under Horizon Europe MSCA Doctoral Networks calls in line with the provisions of the    decision authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

(71)

     The pre-defined categories are as follows: EUR 3 000, EUR 4 500, EUR 6 000, EUR 9 500, EUR 13 000, EUR 18 500, EUR 27 500, EUR 35 500, EUR 47 500 and EUR 60 000.

(72)

     See Article 1 of the UN Convention on the Rights of Persons with Disabilities.

(73)

     An exception to this limit may be granted for medical reasons.

(74)

     In exceptional cases, where a beneficiary is established in a country different from the place where the recruited researcher is hosted, the country correction coefficient of the hosting entity is taken into account during the grant agreement preparation process, in order to ensure the correct budget calculation.

(75)

     Eligibility conditions for unit contributions.

(76)

     Researchers who have successfully defended their doctoral thesis but who have not yet formally been awarded the doctoral degree will not be considered eligible.

(77)

     Country of the main activity: the country where the researcher is physically based when carrying out the main activity and the country of the institution for which the main activity is performed (e.g., employer)

(78)

     1951 Refugee Convention and the 1967 Protocol.

(79)

     Council Directive 2001/55/EC of 20 July 2001 on minimum standards for giving temporary protection  in the event of a mass influx of displaced persons and on measures promoting a balance of efforts between Member States in receiving such persons and bearing the consequences thereof; OJ L 212, 7.8.2001

(80)

   Measured as proposals having passed all relevant evaluation thresholds.

(81)

     Defined as the number of EU Member States or Associated Countries represented in the proposals, not otherwise receiving funds from projects higher up the ranking list (and if equal in number, then by budget).

(82)

     The indicative budget includes budget provisions for the increase of the maximum EU contribution for grants funded under Horizon Europe MSCA Postdoctoral Fellowships calls in line with the provisions of the decision authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

(83)

     The pre-defined categories are as follows: EUR 3 000, EUR 4 500, EUR 6 000, EUR 9 500, EUR 13 000, EUR 18 500, EUR 27 500, EUR 35 500, EUR 47 500 and EUR 60 000.

(84)

     In exceptional cases, where a beneficiary is established in a country different from the place where the recruited researcher is hosted, the country correction coefficient of the hosting entity is taken into account during the grant agreement preparation process, in order to ensure the correct budget calculation.

(85)

     See Article 1 of the UN Convention on the Rights of Persons with Disabilities.

(86)

     Part-time work cannot be requested in order to participate in another MSCA grant at the same time.

(87)

     An exception to this limit may be granted for medical reasons.

(88)

     See Euratom Work Programme and the Horizon Europe Programme guide available on the Funding and Tender Opportunities Portal ( https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/how-to-participate/reference-documents;programCode=HORIZON ) for up-to-date information on the current list of countries associated to the Euratom Programme.

(89)

     Eligibility condition for unit contributions.

(90)

     A medical doctor degree will be accepted only when it corresponds to a doctoral degree or if the researcher can demonstrate their appointment in a position that requires doctoral equivalency (e.g. professorship appointment). Medical doctor degrees corresponding to basic medical training as defined in Annex V of Directive 2005/36/EC will not be considered a doctoral degree

(91)

     Maternity: for each child born within the above-mentioned eligibility period of 8 years, 18 months will be deducted from the experience in research unless the applicant can document a longer parental leave prior to the call deadline. Paternity: for each child born within the above-mentioned eligibility period of 8 years, the documented time of parental leave taken until the call deadline will be deducted from the experience in research.

(92)

     Country of the main activity: the country where the researcher is physically based when carrying out the main activity and the country of the institution for which the main activity is performed (e.g., employer).

(93)

     1951 Refugee Convention and the 1967 Protocol.

(94)

     Council Directive 2001/55/EC of 20 July 2001 on minimum standards for giving temporary protection  in the event of a mass influx of displaced persons and on measures promoting a balance of efforts between  Member States in receiving such persons and bearing the consequences thereof; OJ L 212, 7.8.2001

(95)

     Ibid footnote 97

(96)

       Measured as proposals having passed all relevant evaluation thresholds.

(97)

   Defined as the number of EU Member States or Associated Countries represented in the proposal, not otherwise receiving funds from projects higher up the ranking list (and if equal in number, then by budget).

(98)

     The indicative budget includes budget provisions for the increase of the maximum EU contribution for grants funded under Horizon Europe MSCA Staff Exchanges calls in line with the provisions of the decision authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

(99)

     The pre-defined categories are as follows: EUR 3 000, EUR 4 500, EUR 6 000, EUR 9 500, EUR 13 000, EUR 18 500, EUR 27 500, EUR 35 500, EUR 47 500 and EUR 60 000.

(100)

     See Article 1 of the UN Convention on the Rights of Persons with Disabilities.

(101)

     Secondments to and from branches and departments without separate legal personality that are part of legal entities established in EU Member States or Horizon Europe Associated Countries can take place with entities established in any country other than the country where they are physically located and the country of their mother legal entity.

(102)

     Eligibility condition for unit contributions.

(103)

     In possession of a doctoral degree. Possession of a doctoral degree is defined as a successfully defended doctoral thesis, even if the doctoral degree has yet to be awarded.

(104)

       Measured as proposals having passed all relevant evaluation thresholds.

(105)

     Defined as the number of EU Member States or Associated Countries represented in the proposal, not otherwise receiving funds from projects higher up the ranking list (and if equal in number, then by budget).

(106)

     Note that the 2027 COFUND Call (HORIZON-MSCA-2027-COFUND-01) will only cover doctoral programmes.

(107)

     The indicative budget includes budget provisions for the increase of the maximum EU contribution for grants funded under Horizon Europe MSCA COFUND calls in line with the provisions of the decision authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme. 

(108)

     The pre-defined categories are as follows: EUR 3 000, EUR 4 500, EUR 6 000, EUR 9 500, EUR 13 000, EUR 18 500, EUR 27 500, EUR 35 500, EUR 47 500 and EUR 60 000.

(109)

     See Article 1 of the UN Convention on the Rights of Persons with Disabilities.

(110)

     Part-time work cannot be requested in order to participate in another MSCA grant at the same time.

(111)

     An exception to this limit may be granted for medical reasons.

(112)

     Eligibility condition for unit contributions.

(113)

     Eligibility conditions for unit contributions.

(114)

     Country of the main activity: the country where the researcher is physically based when carrying out the main activity and the country of the institution for which the main activity is performed (e.g., employer)

(115)

     1951 Refugee Convention and the 1967 Protocol.

(116)

     Council Directive 2001/55/EC of 20 July 2001 on minimum standards for giving temporary protection  in the event of a mass influx of displaced persons and on measures promoting a balance of efforts between  Member States in receiving such persons and bearing the consequences thereof; OJ L 212, 7.8.2001

(117)

     Researchers who have successfully defended their doctoral thesis but who have not yet formally been awarded the doctoral degree will not be considered eligible.

(118)

     A medical doctor degree will be accepted only when it corresponds to a doctoral degree or if the researcher can demonstrate their appointment in a position that requires doctoral equivalency (e.g. professorship appointment). Medical doctor degrees corresponding to basic medical training as defined in Annex V of Directive 2005/36/EC will not be considered a doctoral degree.

(119)

     The indicative budget includes budget provisions for the increase of the maximum EU contribution for grants funded under Horizon Europe MSCA Choose Europe for Science calls in line with the provisions of the decision authorising the use of lump sum contributions and unit contributions for Marie Skłodowska-Curie actions under the Horizon Europe Programme.

(120)

     The pre-defined categories are as follows: EUR 3 000, EUR 4 500, EUR 6 000, EUR 9 500, EUR 13 000, EUR 18 500, EUR 27 500, EUR 35 500, EUR 47 500 and EUR 60 000.

(121)

     See eligibility section 5.3

(122)

     In exceptional cases, where a beneficiary is established in a country different from the place where the recruited researcher is hosted, the country correction coefficient of the hosting entity is taken into account during the grant agreement preparation process, in order to ensure the correct budget calculation.

(123)

     See Article 1 of the UN Convention on the Rights of Persons with Disabilities.

(124)

     Part-time work cannot be requested in order to participate in another MSCA grant at the same time.

(125)

     An exception to this limit may be granted for medical reasons.

(126)

     Eligibility conditions for unit contributions.

(127)

     1951 Refugee Convention and the 1967 Protocol.

(128)

     Council Directive 2001/55/EC of 20 July 2001 on minimum standards for giving temporary protection  in the event of a mass influx of displaced persons and on measures promoting a balance of efforts between  Member States in receiving such persons and bearing the consequences thereof; OJ L 212, 7.8.2001

(129)

     A medical doctor degree will be accepted only when it corresponds to a doctoral degree or if the researcher can demonstrate their appointment in a position that requires doctoral equivalency (e.g. professorship appointment). Medical doctor degrees corresponding to basic medical training as defined in Annex V of Directive 2005/36/EC will not be considered a doctoral degree.

(130)

     Eligibility condition for unit contributions.

(131)

     24 months of the initial stage and 24 months of the second phase

(132)

     36 months of the initial stage and 24 months of the second phase

(133)

    ISO 3166 alpha-2 , except for Greece and the United Kingdom (EL and UK used respectively instead of GR and GB).

Top

EN

Annex III

Horizon Europe

Work Programme 2026-2027

3. Research Infrastructures

Table of contents

Introduction    

Calls    

Call - Research Infrastructures 2026    

Overview of this call    

Call - Research Infrastructures 2027    

Overview of this call    

Destinations    

Destination INFRADEV - Consolidation and evolution of the European Research Infrastructure landscape (2026-27)    

HORIZON-INFRA-2026-DEV-01-01: Research infrastructure concept development including major upgrades or extensions of existing infrastructures    

HORIZON-INFRA-2026-DEV-01-02: Consolidation of the research infrastructure landscape – pilots for strategic coordination, synergies and simplified access pathways, by large thematic clusters of pan-European research infrastructures    

HORIZON-INFRA-2026-DEV-01-03: Consolidation of the research infrastructure landscape – individual support for evolution, long-term sustainability and emerging needs of pan-European research infrastructures    

HORIZON-INFRA-2026-DEV-01-04: Strengthening the human capital managing research infrastructures, including in international context    

HORIZON-INFRA-2026-DEV-01-05: Research infrastructures as accelerators of the integration of Ukraine in the European Research Area    

HORIZON-INFRA-2026-DEV-01-06: Strengthening the international dimension of ESFRI and/or ERIC research infrastructures    

HORIZON-INFRA-2026-DEV-01-07: Risk management, mitigation and contingency for ESFRI/ERIC and other world-class research infrastructures    

HORIZON-INFRA-2027-DEV-01-01: Preparatory phase of new ESFRI research infrastructure projects    

HORIZON-INFRA-2027-DEV-01-02: Consolidation of the research infrastructure landscape – development of complementarities, synergies and/or integration between a set of pan-European research infrastructures    

HORIZON-INFRA-2027-DEV-01-03: Consolidation of the research infrastructure landscape – individual support for evolution, long-term sustainability and emerging needs of pan-European research infrastructures    

Destination INFRAEOSC - Enabling an operational, open and FAIR EOSC ecosystem (2026-27)    

HORIZON-INFRA-2026-01-EOSC-01: Uptake of FAIR data management practices and of EOSC by research communities and research infrastructures (EOSC Partnership)    

HORIZON-INFRA-2026-01-EOSC-02: Trusted frameworks for secure and efficient data sharing in EOSC (EOSC Partnership)    

HORIZON-INFRA-2027-01-EOSC-01: Expanding and deepening the EOSC Federation (EOSC Partnership)    

HORIZON-INFRA-2027-01-EOSC-02: Strengthening the potential of the EOSC for knowledge valorisation and industry-academia collaboration (EOSC Partnership)    

Destination INFRASERV - Research infrastructures services to support a healthier future, a global climate and energy vision, a circular and resilient economy, and to advance frontier knowledge (2026-27)    

HORIZON-INFRA-2026-SERV-01-01: Implementing digital services to empower neuroscience research for health and brain inspired technology via EBRAINS    

HORIZON-INFRA-2027-SERV-01-01: Access to research infrastructures, their resources and services: large-scale pilots for more integrated scheme across (sub)domains    

HORIZON-INFRA-2027-SERV-01-02: Access to research infrastructure services to enable R&I addressing EU priorities and emerging challenges    

HORIZON-INFRA-2027-SERV-01-03: Connecting research infrastructures and a wider user community across the European Research Area through access to advanced research infrastructure services    

Destination INFRATECH - Next generation of scientific instrumentation, tools, methods, and advanced digital solutions of research infrastructures and fostering innovation and co-creation with industry (2026-27)    

HORIZON-INFRA-2026-TECH-01-01: R&D for the next generation of scientific instrumentation, tools, methods, digitalisation and solutions for research infrastructure upgrades    

HORIZON-INFRA-2026-TECH-01-02: Digital twins and/or their major components for environment, climate and security    

HORIZON-INFRA-2027-TECH-01-01: Testing and optimising models of co-creation of advanced research infrastructure technologies    

HORIZON-INFRA-2027-TECH-01-02: Pioneering Destination Earth for a Sustainable Future: Large-Scale Pilots and Demonstrators    

Destination INFRANET – Network connectivity in research and education - enabling collaboration without boundaries    

Other Actions not subject to calls for proposals    

Grants to Identified Beneficiaries    

1. Sustaining the EOSC monitoring mechanism    

2. Coordination and Monitoring of the European Research Infrastructure Consortia (ERICs)    

3. Reinforcing the coordination and support to the EOSC Federation    

4. Strengthening the international dimension of ESFRI and/or ERIC research infrastructures – consolidating the SESAME facility    

Specific Grant Agreements to the FPA    

1. SGA to the FPA for Research and Education Networks (2027)    

Expert contract actions    

1. External expertise 2026    

2. External expertise 2027    

Procurement    

1. Managed services for the EOSC Platform (EOSC EU Node)    

2. Support for EOSC EU Node Service Verification and Validation activities    

Specific Features For Research Infrastructures    

Budget    

Introduction

The Horizon Europe Programme objectives are pursued through this Research Infrastructures work programme part endowing Europe with world-class sustainable 1 research infrastructures which are open and accessible to the best researchers and innovators from Europe and beyond. These research infrastructures are unique assets that stimulate researchers and innovators to "Choose Europe for Science".

This work programme supports activities to consolidate, evolve, open, integrate and interconnect a world leading ecosystem of research services for researchers and innovators in Europe, encompassing both national and pan-European infrastructures. The aim is to cover the continuum of needs from the creation of fundamental knowledge to technology development and innovation, while supporting open science.

The programme is building on continuous policy development under the European Research Area, including the strategy-led approach and roadmap exercise of the European Strategy Forum on Research Infrastructures (ESFRI) and the use of the European Research Infrastructure Consortium (ERIC) legal instrument. The programme is highly relevant to the Political Guidelines for the European Commission 2024-2029, which highlight that “to lead on innovation, we need to create the conditions for researchers to thrive. This means providing the infrastructure and innovative laboratories they need to test and develop ideas”.

It supports several actions in the European Strategy on Research and Technology Infrastructures 2 , including on schemes for transnational access, on framework for maintenance and upgrade of instrumentation and services, on expanding and enhancing the European Open Science Cloud (EOSC) Federation, on strengthening international dimensions, and on attracting and growing talent. It also supports the EU Startup and Scaleup Strategy 3 , notably for access of innovative companies to European infrastructures 4 , as well as the goals of the AI in Science Strategy and of the Resource for AI Science in Europe (RAISE) contributing to the pooling of resources, data and computing capacity for accelerating the responsible use of AI in science 5 . Finally, it supports many thematic strategies such as on life sciences 6 and on advanced materials 7 , as infrastructures for R&I are one of the key components of these strategies, both through evolving infrastructures in these domains and through improving access schemes 8 .

The programme aims to improve the sustainability of the research infrastructures ecosystem and synergies amongst funding sources, support human resources and skills development for an optimal functioning of research infrastructures, and reinforce the international dimension of research infrastructures in particular with regards to shared global challenges.

Another key aim of the programme is to continue enabling transnational access to research infrastructure services targeting both curiosity-driven research and challenge-driven research, considering also the development of new or customised services to better serve interdisciplinary approaches. Topics under this work programme aim at more integrated and sustained opportunities for transnational access, and it will also promote the training and educational dimensions of access while making sure these activities do not come at the cost of already overbooked transnational access services. The work programme also aims at fostering the uptake of research infrastructure services in other parts of the Horizon Europe programme.

A third key aim is to promote collaboration in the upgrading and design of scientific instruments and tools, including through cooperation with industry and through creating research infrastructure innovation ecosystems, including further engagement with SMEs, startups and scaleups. Reduction of the environmental footprint of research infrastructures is also a focus.

In line with the Strategic R&I Agenda of the 2021-2030 EOSC co-programmed European Partnership, the programme aims at ensuring that open science policies, practices and skills become the norm across the ERA and that the EOSC federation is enlarged through connecting existing research infrastructures in Europe and providing additional value added services based on user needs, also with the view of enabling the European contribution to a web of FAIR data and services.

Finally, the further evolution of the Destination Earth flagship initiative as a digital model of the Earth on a global scale is also supported, with a strong Artificial Intelligence component of the New Digital Twins.

Eligibility to participate is also subject to the ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility condition (see General Annex B of the General Annexes)’.

The Research Infrastructures work programme is structured around the following five destinations:

INFRADEV - Consolidation and evolution of the European Research Infrastructure landscape, to develop an integrated European ecosystem of research infrastructures, including single-sited facilities, distributed facilities and networks of facilities providing joint services.

INFRAEOSC - Enabling an operational, open and FAIR EOSC ecosystem, to contribute to a web of FAIR (Findable, Accessible, Interoperable, Reusable) research data and provide a trusted and secure federated system of research data and services (EOSC Federation) for researchers in the EU and Associated Countries to store, share, process and reuse within and across disciplines and borders FAIR research outputs and tools for research, innovation and educational purposes.

INFRASERV - Research infrastructures services to support a healthier future, a global climate and energy vision, a circular and resilient economy, and to advance frontier knowledge, to support transnational access to state-of-the-art facilities for researchers and innovators, relevant for a large research domain or in support of societal challenge and EU priorities.

INFRATECH - Next generation of scientific instrumentation, tools, methods, and advanced digital solutions of research infrastructures, and fostering innovation and co-creation with industry, to support research infrastructure needs for technology development to maintain and upgrade their services and to create new ones, and to support the Destination Earth initiative.

INFRANET - Network connectivity in Research and Education – Enabling collaboration without boundaries, providing high-bandwidth networks and network services to interconnect researchers, data and computing resources in a non-discriminatory way regardless of the location of the users and the resources to allow scientists to conduct excellent research.

Calls

Call - Research Infrastructures 2026

HORIZON-INFRA-2026-01

Overview of this call 9

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 10

Indicative number of projects expected to be funded

2026

Opening: 10 Mar 2026

Deadline(s): 16 Jun 2026

Destination INFRADEV - Consolidation and evolution of the European Research Infrastructure landscape (2026-27)

HORIZON-INFRA-2026-DEV-01-01: Research infrastructure concept development including major upgrades or extensions of existing infrastructures

RIA

10.00

2.00 to 3.00

4

HORIZON-INFRA-2026-DEV-01-02: Consolidation of the research infrastructure landscape – pilots for strategic coordination, synergies and simplified access pathways, by large thematic clusters of pan-European research infrastructures

RIA

40.00

4.00 to 8.00

6

HORIZON-INFRA-2026-DEV-01-03: Consolidation of the research infrastructure landscape – individual support for evolution, long-term sustainability and emerging needs of pan-European research infrastructures

RIA

9.90

3.00 to 4.50

3

HORIZON-INFRA-2026-DEV-01-04: Strengthening the human capital managing research infrastructures, including in international context

CSA

2.00

Around 2.00

1

HORIZON-INFRA-2026-DEV-01-05: Research infrastructures as accelerators of the integration of Ukraine in the European Research Area

RIA

8.00

Around 8.00

1

HORIZON-INFRA-2026-DEV-01-06: Strengthening the international dimension of ESFRI and/or ERIC research infrastructures

CSA

8.00

1.00 to 1.50

5

HORIZON-INFRA-2026-DEV-01-07: Risk management, mitigation and contingency for ESFRI/ERIC and other world-class research infrastructures

RIA

10.00

1.00 to 4.00

3

Destination INFRAEOSC - Enabling an operational, open and FAIR EOSC ecosystem (2026-27)

HORIZON-INFRA-2026-01-EOSC-01: Uptake of FAIR data management practices and of EOSC by research communities and research infrastructures (EOSC Partnership)

RIA

40.00

Around 40.00

1

HORIZON-INFRA-2026-01-EOSC-02: Trusted frameworks for secure and efficient data sharing in EOSC (EOSC Partnership)

CSA

10.00

3.00 to 5.00

2

Destination INFRASERV - Research infrastructures services to support a healthier future, a global climate and energy vision, a circular and resilient economy, and to advance frontier knowledge (2026-27)

HORIZON-INFRA-2026-SERV-01-01: Implementing digital services to empower neuroscience research for health and brain inspired technology via EBRAINS

RIA

32.00

Around 32.00

1

Destination INFRATECH - Next generation of scientific instrumentation, tools, methods, and advanced digital solutions of research infrastructures and fostering innovation and co-creation with industry (2026-27)

HORIZON-INFRA-2026-TECH-01-01: R&D for the next generation of scientific instrumentation, tools, methods, digitalisation and solutions for research infrastructure upgrades

RIA

110.00

5.00 to 10.00

11

HORIZON-INFRA-2026-TECH-01-02: Digital twins and/or their major components for environment, climate and security

RIA

15.00

5.00 to 7.50

2

Overall indicative budget

294.90

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Research Infrastructures 2027

HORIZON-INFRA-2027-01

Overview of this call 11

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 12

Indicative number of projects expected to be funded

2027

Opening: 09 Mar 2027

Deadline(s): 15 Jun 2027

Destination INFRADEV - Consolidation and evolution of the European Research Infrastructure landscape (2026-27)

HORIZON-INFRA-2027-DEV-01-01: Preparatory phase of new ESFRI research infrastructure projects

CSA

30.00

1.50 to 3.50

9

HORIZON-INFRA-2027-DEV-01-02: Consolidation of the research infrastructure landscape – development of complementarities, synergies and/or integration between a set of pan-European research infrastructures

RIA

20.00

2.00 to 5.00

4

HORIZON-INFRA-2027-DEV-01-03: Consolidation of the research infrastructure landscape – individual support for evolution, long-term sustainability and emerging needs of pan-European research infrastructures

RIA

29.50

3.00 to 4.50

8

Destination INFRAEOSC - Enabling an operational, open and FAIR EOSC ecosystem (2026-27)

HORIZON-INFRA-2027-01-EOSC-01: Expanding and deepening the EOSC Federation (EOSC Partnership)

COFUND

40.00

Around 40.00

1

HORIZON-INFRA-2027-01-EOSC-02: Strengthening the potential of the EOSC for knowledge valorisation and industry-academia collaboration (EOSC Partnership)

CSA

8.00

2.50 to 4.00

2

Destination INFRASERV - Research infrastructures services to support a healthier future, a global climate and energy vision, a circular and resilient economy, and to advance frontier knowledge (2026-27)

HORIZON-INFRA-2027-SERV-01-01: Access to research infrastructures, their resources and services: large-scale pilots for more integrated scheme across (sub)domains

RIA

105.00

Around 35.00

3

HORIZON-INFRA-2027-SERV-01-02: Access to research infrastructure services to enable R&I addressing EU priorities and emerging challenges

RIA

35.00

Around 6.00

6

HORIZON-INFRA-2027-SERV-01-03: Connecting research infrastructures and a wider user community across the European Research Area through access to advanced research infrastructure services

RIA

12.00

Around 3.00

4

Destination INFRATECH - Next generation of scientific instrumentation, tools, methods, and advanced digital solutions of research infrastructures and fostering innovation and co-creation with industry (2026-27)

HORIZON-INFRA-2027-TECH-01-01: Testing and optimising models of co-creation of advanced research infrastructure technologies

RIA

30.00

10.00 to 15.00

2

HORIZON-INFRA-2027-TECH-01-02: Pioneering Destination Earth for a Sustainable Future: Large-Scale Pilots and Demonstrators

RIA

30.00

7.00 to 12.00

3

Overall indicative budget

339.50

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Destinations

Destination INFRADEV - Consolidation and evolution of the European Research Infrastructure landscape (2026-27)

The objective of this destination is to consolidate and evolve the European research infrastructure landscape, considering notably the development of pan-European research infrastructures prioritised by ESFRI and the ERICs, and underpinning an effective, coherent and agile European Research Area through an integrated and efficient ecosystem of research infrastructures in Europe. It supports actions targeting various stages of the life-cycle of research infrastructures to develop an integrated European ecosystem of research infrastructures, including single-sited facilities, distributed facilities and networks of facilities providing joint services.

The expected impact of the EU intervention on the activities supported under this destination notably includes:

1.Awareness, findability, and accessibility of research infrastructures: from a European portfolio of individual research infrastructures to a European portfolio of user- and challenge-driven complementary R&I services of European interest.

2.Further sustainability, consolidation and evolution of the European research infrastructure landscape, with the objective to enhance its capacity and capability to support the continuum of research and innovation needs, with due attention to closing the innovation gap by increased participation of organisations from widening countries and candidate countries. Benefits of developments, notably digitalisation, should be balanced against possible costs for the environment.

3.Reinforced international dimension of European research infrastructures, considering EU priorities and targeted objectives, notably for addressing global challenges, taking account of global initiatives and relevant lead ESFRI/ERICs involvement, pooling facilities, data, expertise and other resources and cooperation with other world regions of specific interest, with due attention to research security.

4.Strengthened Ukrainian research infrastructure community of users and staff, including individual scientists displaced from Ukraine.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions and Innovation Actions falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Proposals are invited against the following topic(s):

HORIZON-INFRA-2026-DEV-01-01: Research infrastructure concept development including major upgrades or extensions of existing infrastructures

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 2.00 and 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 10.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 13 .

Expected Outcome: Projects are expected to contribute to all the following expected outcomes:

1.support to planning and decision making for research infrastructures at the national (e.g. funding bodies, governments) and European level (e.g. ESFRI) through solid science cases, including expected scientific breakthrough, gaps analyses and feasibility/design studies for future research infrastructures or major upgrades or extensions of existing ones;

2.a better alignment of the development of the European research infrastructure landscape with the advancements of excellent science, frontier research and technology innovation;

3.increased performance, scientific capacity and excellence of the European research infrastructure landscape;

4.new services and access opportunities available to the research community, allowing to better tackle scientific and societal challenges, notably in support of strategic research and innovation agendas developed by key EU initiatives;

5.reduction of environmental (including climate-related) impacts as well as optimisation of resource and energy consumption integrated in the very early phase of development of new research infrastructures or major upgrades or extensions of existing ones.

Scope: This topic aims at supporting the development of new concepts for the next generation of research infrastructures of European interest 14 , single- or multi-sited, distributed or virtual, that none or few countries might individually be able to implement. All fields of research can be considered.

Major upgrades or extensions of existing infrastructures may also be considered if the result is significantly transformative with regards to the scientific outputs or the technical approach of the infrastructure and equivalent to a new infrastructure concept. Proposals considering routine maintenance, incremental gains or just a new component of a research infrastructure are not in scope of this topic 15 .

When developing a new concept, applicants should assess as a first option extending the scope of already existing infrastructures and/or sustainably integrating existing pan-European and national capacities to address the specific research infrastructure service needs, identifying what is missing and the new developments necessary. 16 Otherwise, applicants should explicitly justify why this option cannot be considered.

Proposals should demonstrate the uniqueness and added value for the European Research Area (ERA) of the new, upgraded or extended research infrastructure, considering the European landscape of research infrastructures and the ESFRI landscape analysis and, where relevant, the capacity to better tackle scientific and societal challenges, notably in support of strategic research and innovation agendas developed by key EU initiatives including European Partnerships 17 .

Proposals for research infrastructure concept development should tackle all key questions concerning the technical and conceptual feasibility of new, upgraded or extended fully fledged user facilities.

In this respect, proposals should address all of the following aspects:

1.demonstrate relevance in relation to the ERA, including to the existing landscape, and the expected advancement with respect to the state-of-art of the new, upgraded or extended infrastructure;

2.highlight the research challenges the new, upgraded or extended research infrastructures will make possible to address, including at global level;

3.indicate the gaps in the research infrastructure landscape the new, upgraded or extended infrastructure will cover and the synergies with other existing infrastructures at European and global level, including those co-financed from other EU instruments such as through Cohesion funds;

4.indicate, when relevant, the potential impact of the new research infrastructure at regional level.

Proposals should also convincingly demonstrate that the project will effectively:

1.identify technologies, with due attention to technology sovereignty, and the architecture (e.g. single site or distributed) for developing the research infrastructure;

2.identify scientific user communities (and their related needs) that will benefit from access to research infrastructure services, including scientific data and instrumentation, and develop the planning of research services to users;

3.identify governance options as well as strategic approaches for institutional/stakeholders’ commitment and engagement, as well as for ensuring a wide membership;

4.develop initial financial plans for the implementation and operation of the new, upgraded or extended research infrastructure as well as preliminary ideas for long-term sustainability, including synergies with other funds and programmes (e.g. ERDF for construction);

5.develop plans for efficient data curation and preservation and for the provision of access to data collected or produced by the future infrastructure, in line with the FAIR principles.

When relevant, ethical dimensions, environmental (including climate-related) impacts as well as the optimisation of resource and energy use should be integrated in the concept development of new, upgraded or extended research infrastructures. In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement.

Proposals could consider the inclusion of the European Commission's Joint Research Centre (JRC) Flagship Research Infrastructure projects that the JRC is planning to set-up to address new and upcoming priorities of the European Commission in the coming decades. In that respect, the JRC will consider collaborating with any successful proposal and this collaboration, when relevant, should be established after the proposal’s approval.

HORIZON-INFRA-2026-DEV-01-02: Consolidation of the research infrastructure landscape – pilots for strategic coordination, synergies and simplified access pathways, by large thematic clusters of pan-European research infrastructures

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 40.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering the different domains, grants will be awarded to applications not only in order of ranking but at least also to those proposals that are the highest ranked within each ESFRI domain, provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries will be subject to the additional access rights: beneficiaries shall grant royalty-free access to their intellectual property relating to tools, standards, specifications, and other relevant outputs generated by this action to the EU institutions and to the beneficiaries of projects funded by the EU in view of a more sustained and integrated EU access scheme. This access shall be provided through a mechanism to be defined in the proposal, during and beyond the lifespan of the Grant Agreement .

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 18 .

Expected Outcome:

1.Policy contribution, impact and visibility of research infrastructures of European interest, by large thematic domain, to relevant EU policy and priority initiatives, including beyond research, at national, regional, European and global level.

2.Improved coordination, complementarities, and where applicable, interoperability, harmonisation, integration and synergies among research infrastructures within large thematic domains and, where relevant, across domains.

3.A European portfolio of R&I services of European interest, supported by a common front page and few single-entry point access portals, integrated or interoperable catalogues of R&I services and converging access conditions and selection procedures, strengthening the European landscape of ESFRI-prioritised infrastructures and other world-class research infrastructures by large thematic domains.

4.Increased awareness, findability and accessibility of research infrastructures for European researchers and innovators; simplified and adapted access pathways for new needs or new communities of users (e.g. where relevant, multidisciplinary R&I, EU collaborative research projects, EU operational or deployment programmes, public authorities, and industry, including SMEs, startups and scaleups).

Scope: This topic aims at equipping large thematic clusters of research infrastructures of European interest with a policy arm combined with a technical arm, to increase awareness, findability and accessibility, better matching user needs. This thematic clustering is aligned with ESFRI approach: proposals should explicitly state which ESFRI domain 19 they address (see specific conditions on procedure for ranking proposals). Proposals should foresee close collaboration across projects under this topic to ensure, where applicable, policy coordination, technical interoperability and other synergies.

Building on the clusters under Horizon 2020 20 and Horizon Europe 21 , on the development of catalogues of services, and on new access pathways and improved services such as under Horizon Europe INFRASERV 22 projects, proposals should address all of the following aspects:

1.Strengthening the representation of the research infrastructures cluster, as a single or coordinated voice, in key EU policy developments and strategic initiatives and contribute to policies in their domain with a research infrastructure component. Coordination with cross-domains fora, such as the ERIC Forum and EIROforum should also be ensured.

2.Strengthening coordination among research infrastructures to foster complementarities, interoperability, harmonisation, integration and synergies within the domain, and where relevant with other domains to address increasingly complex and multidisciplinary science and technology challenges.

3.Developing, optimising and connecting catalogues of research infrastructures services of European interest. Attention is required to new users, notably researchers and innovators from widening countries and candidate countries, industry (including SMEs, startups and scaleups), early-stage career researchers, and non-expert users. Flexibility to address future needs should be considered.

4.Developing and implementing intermediary services, user support, tools and notably AI assisted research infrastructure services navigation. When relevant, resulting data and digital services should be made accessible through EOSC.

5.Elaborating and promoting indicators flagging the strategic relevance of specific research infrastructures services to key EU R&I priorities and initiatives, including through common or coordinated impact assessments, and possible validation mechanisms with these initiatives.

Proposals should involve, not necessarily as beneficiaries, ESFRI Landmarks and Projects and/or ERICs in the domain, other research infrastructures that are international European research organisations and, where relevant, well-established networks of key European research infrastructures open to external users. Proposals should elaborate on which key EU priorities and initiatives (such as Horizon Europe partnerships, missions) they will consider and the nature and objectives of the envisaged coordination mechanisms or joint activities.

To ensure a holistic view from design to implementation of possible access schemes, proposals should ensure strong and continuous collaboration with the cross-domain preparatory action exploring a more integrated and sustainable scheme for access to research infrastructures HORIZON-INFRA-2025-01-DEV-05 23 , and the actions supported under topics HORIZON-INFRA-2027-01-SERV-01 and HORIZON-INFRA-2027-01-SERV-02. This collaboration should ensure a common front page to all above actions highlighting the common objectives of EU supported access, the main conditions and requirements, providing preliminary guidance on access opportunities and directing to the single-entry point portal of each pilot of HORIZON-INFRA-2027-SERV-01-01. The collaboration should also promote simplified access pathways, good practices on call conditions, converging access modalities and selection process, and effective governance of the set of projects acting as an access programme with appropriate advisory bodies.

Proposals could consider the inclusion of the European Commission's Joint Research Centre (JRC) research infrastructures in the area of health and food. In that respect, the JRC will consider collaborating with any successful proposal and this collaboration, when relevant, should be established after the proposal’s approval.

HORIZON-INFRA-2026-DEV-01-03: Consolidation of the research infrastructure landscape – individual support for evolution, long-term sustainability and emerging needs of pan-European research infrastructures

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 9.90 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

Due to the scope of this topic, proposals must include at least one of the ESFRI Landmarks 24 or European Research Infrastructure Consortia (ERICs) 25 as beneficiary. Such beneficiaries, and the research infrastructure(s) that they operate, must be explicitly identified in the proposal. For distributed ERIC the ERIC must be the beneficiary.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 26 .

The funding rate is 80% of the eligible costs.

Expected Outcome: Project results are expected to contribute to several of the following expected outcomes:

1.better structured and strengthened European research infrastructure landscape;

2.new services available to a wider user community, including participants in other parts of Horizon Europe, allowing to better tackle scientific and societal challenges;

3.increased capacity to address EU policy priorities and/or socio-economic challenges;

4.reinforced global competitiveness of the European Research Area;

5.reduction of environmental (including climate-related) impacts as well as optimisation of resource and energy consumption integrated through the full life cycle of research infrastructures;

6.increased long-term sustainability of European research infrastructures.

Scope: This topic targets the consolidation of the EU research infrastructures landscape through the support, together with the countries that are members of the research infrastructures, to the strengthening, long-term sustainability, reorientation or evolution of ESFRI Landmarks 27 or European Research Infrastructure Consortia (ERICs) 28 .

The proposed action should justify the specific objectives and focus on activities that are critical for the sustainability and optimised use of the ESFRI Landmarks or ERICs, such as activities aiming at several of the following objectives:

1.enlargement of the membership or broadening of the base of participating countries, notably widening countries and candidate countries;

2.addressing critical aspects raised following an assessment or monitoring exercise, e.g. in the context of ESFRI activities;

3.reinforcing international cooperation;

4.revision of business/funding plan;

5.development of managerial and technical skills for research infrastructure staff;

6.structuring and strengthening of national/thematic nodes;

7.extension of remote and/or virtual access;

8.management of research data according to the FAIR principles;

9.reorientation or evolution of the research infrastructure scope;

10.development, update and or implementation of impact assessment of the research infrastructure.

In case of reorientation or evolution of the research infrastructure scope, activities should fill gaps in the research infrastructures landscape 29 , enabling the research infrastructure to address new research or societal challenges and/or serve new user communities, increasing and improving service capacity and/or integrating new resources/facilities.

Due attention should be given to related EU initiatives, strategies and priorities and, where relevant, to complementarity and relevance to activities in other parts of Horizon Europe, such as better addressing SRIAs of Horizon Europe partnerships. Proposals should explain concrete complementarities and any synergies with previous or current EU grants, notably under the research infrastructures part of the Horizon Europe work programme, e.g. INFRADEV and INFRATECH grants.

Given the funding rate, proposals should ensure a minimum adequate backing by the beneficiaries, who should provide the remaining share for the activities covered by the Grant Agreement and foster the sustainability of the ESFRI Landmark or ERIC.

Specific attention should be given, where relevant, to the greening of technologies and methodologies used by the research infrastructure, to the interaction with industry/SMEs, to the fostering of the innovation potential of the infrastructures, and to their integration into local, regional and global innovation ecosystems.

HORIZON-INFRA-2026-DEV-01-04: Strengthening the human capital managing research infrastructures, including in international context

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 2.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.00 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 30 .

Expected Outcome: Projects are expected to contribute to all the following expected outcomes:

1.Specialised training provided to the staff managing research infrastructures of European interest, enhancing the skills of RI research infrastructure staff as regards planning future operations and engaging with their various user communities and stakeholder groups (including funding agencies, academia, industry).

2.Broader understanding of the EU research infrastructures policy, the possibilities for transnational access and the basics of international research infrastructures cooperation, be it via ERIC creation and development or other governance models.

3.Shared understanding of the possibilities and potential offered by EU policies and funding instruments, improving the impact of research infrastructures and enhancing European scientific capacities. The completion of the training programme should lead to recognised accreditation in ECTS points.

Scope: This topic aims at the training of staff managing research infrastructures, the adequate supply of skilled human resources, and strengthening and sustaining specific education curricula and courses with due attention to widening and candidate countries as well as to evolving research infrastructure environments.

The complexity of research infrastructures and the exploitation of their full potential require adequate skills for their managers. Research infrastructures are built and operated at the cutting edge of what is technologically feasible, involving a high associated risk that needs to be managed.

They may involve a wide consortium of partners for their funding, construction and operation, either because they are distributed research infrastructures, or because certain problems are of a scale that can only be tackled through European and international cooperation.

This renders their governance and the associated financial and legal issues a complex problem. The skills and expertise specifically needed to effectively construct, manage and use research infrastructures are therefore not widely available.

Proposals should build on existing curricula such as those developed under the RItrainplus 31 project and strengthen and continue professionalising the training offer including through sustained and recognised executive master’s in management of research infrastructures. Proposals should pay attention to the upskilling of research infrastructures managers with regard to the impact of increased digitalisation of research infrastructures, including use of AI, further internationalisation and geopolitical changes, and closer links to industry. Proposals should engage with pan-European research infrastructures such as those prioritised by ESFRI, ERICs and EIROforum, to ensure the proposed training fits the needs of complex research infrastructures.

The proposed action should include several of the following objectives:

1.Support the training of staff managing research infrastructures, and exchanges of staff and best practices. The training may also be offered to students engaged with a research infrastructure or aiming at a research infrastructure career path.

2.Develop specific education curricula and courses targeting pan-European research infrastructures, taking into account their diverse scientific fields and organisational models; in doing this, engagement with universities is expected.

3.Offer dedicated scholarships to staff in Ukrainian research infrastructures, while promoting and disseminating training opportunities to widening and candidate countries in particular.

4.Address training topics such as the socioeconomic impact of research infrastructures, scientific capabilities and capacity, engagement with academic users and industry (including understanding the needs of startups and scaleups), in-depth guidance on State Aid rules, and the long-term financial and environmental sustainability of the infrastructure’s activities.

5.Address the areas of data management, exploitation and stewardship skills, FAIR principles and data protection rules.

6.Pay attention to training research infrastructure staff in the different governance models for international research infrastructure collaborations, across different scientific fields, taking stock of the rapidly evolving geopolitical context.

7.Address training on research security and provide an overview of how research infrastructures need to face these challenges in their operations.

8.Report on the sustainability of the training activities, and engage with national agencies, ERICs, international organisations, and other relevant stakeholders.

9.Demonstrate an evolution based on related past activities and the experience gained in projects such as RAMIRI (Realising and Managing International Research Infrastructures) and RItrain (Research Infrastructures Training Programme).

HORIZON-INFRA-2026-DEV-01-05: Research infrastructures as accelerators of the integration of Ukraine in the European Research Area

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

The following additional eligibility criteria apply: in order to achieve the expected objectives of the action, the application must include at least three legal entities as beneficiaries established in different Member States/Associated Countries, including at least one legal entity established in the government controlled territories of Ukraine.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 32 .

Expected Outcome: Project results are expected to contribute to all the following outcomes:

1.Strong and sustainable collaboration frameworks between Ukrainian and European research infrastructures, supporting joint research initiatives.

2.An early phase implementation plan for the reconstruction and upgrade of Ukrainian research infrastructures, aligning with the priorities of the ERA Policy Agenda.

3.Remote access of Ukrainian researchers and innovators to European research infrastructures, allowing them to participate in scientifically excellent projects across various fields and enhancing their integration into the ERA.

4.Remote fellowships for researchers based in Ukraine for research activities related to scientific instrumentation and advanced methods in collaboration with European research infrastructures.

5.Effective systems for monitoring and evaluating the progress and impact of integration efforts, ensuring objectives are met and supporting continuous improvement and adaptation.

Scope: The objective of the topic is the utilisation of Europe’s research infrastructure landscape to facilitate the integration of Ukraine in the European Research Area. Proposals should build on the Coordination and Support Action “assessing the state of research infrastructure in Ukraine” resulting from the 2024 topic. Moreover, they should include the provision of remote fellowships for researchers based in Ukraine to collaborate on technology development with European research infrastructures, building on the model of the EURIZON project 33 (proposals may use financial support to third parties for that purpose).

Proposals should address all of the following aspects:

1.Support the design of an early phase implementation plan of the roadmap of the development, reconstruction and reorientation of Ukraine’s RI capacity based on the 2024 Coordination and Support Action, and the recommendations of the EURIZON project.

2.Foster collaboration and networking with Ukrainian research infrastructures, enabling joint research initiatives via remote fellowships, shared use of facilities, including possible short-term researcher exchanges, and the co-development of scientific methodologies, while supporting initiatives of European research infrastructures donating equipment to Ukrainian research institutions.

3.Offer remote access for Ukrainian researchers to European RIs, supporting their participation in scientifically excellent projects across various fields, thereby enhancing their research capabilities and integration into the European scientific community.

4.Identify and align investment opportunities, leveraging EU funding mechanisms to prioritise the development and reconstruction of Ukrainian research infrastructures.

Proposals could consider the inclusion of the European Commission's Joint Research Centre (JRC) research infrastructure offering transnational access to external users to a portfolio of 18 facilities in the nuclear and non-nuclear area. In that respect, the JRC will consider collaborating with any successful proposal and this collaboration, when relevant, should be established after the proposal’s approval.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement.

HORIZON-INFRA-2026-DEV-01-06: Strengthening the international dimension of ESFRI and/or ERIC research infrastructures

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 1.00 and 1.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

If eligible for funding, legal entities established in non-associated third countries may exceptionally participate in this Coordination and support action as a beneficiary or affiliated entity.

The following additional eligibility criteria apply: in order to achieve the expected objectives of the action, consortia must include, as beneficiary, at least one ESFRI Landmark 34 and/or European Research Infrastructure Consortium (ERIC) 35 and, as beneficiary or as associated partner, at least one legal entity established in a non-associated third country.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 36 .

Expected Outcome: Project results are expected to contribute to several of the following expected outcomes:

1.New or enhanced, effective cooperation of European research infrastructures with key international partners;

2.Strengthened position of European research infrastructures in the global research infrastructure landscape;

3.Increased opportunities for the development of global research infrastructures, including proposals expanding the geographical coverage of ongoing collaborations;

4.Increased capacity to address societal challenges with a global dimension, including collaborations in areas such as environmental monitoring or health;

5.Reinforced global competitiveness and performance of the European Research Area.

Scope: This topic aims at supporting the cooperation of pan-European research infrastructures with their international (non-European) counterparts, and/or fostering the international engagement of ESFRI and ERIC research infrastructures through their involvement in global research infrastructure initiatives 37 .

Proposals should describe shared objectives and governance of the collaboration, building on the criteria developed by the Group of Senior Officials on Global Research Infrastructures 38 .

Proposals should pay attention to the following aspects:

1.The long-term sustainability of joint activities; beyond the immediate results of the project, the prospects for the collaboration to be sustained should be described. Methods and governance models should be explored. Activities leading to agreements on data sharing or co-financing reciprocal activities are welcome.

2.Opportunities (access and data sharing) available to European scientists; proposals should elaborate on the data dimension of their activities, and in which way access will be ensured over time.

3.Fostering global interoperability and coverage (when appropriate) of data;

4.Exchanging best practices between user communities and managers of research infrastructures as regard, for instance, harmonisation of tests, standards, reference materials, interoperability and data handling.

While the main target of this topic is the cooperation between an individual pan-European infrastructure and its international counterparts in one or more third countries, proposals could also involve a set of pan-European infrastructures with their international counterparts if relevant for the chosen research field.

Proposals should describe the EU benefit of any EU contribution requested by non-associated third countries, by explaining the new services or knowledge made accessible to EU researchers via the collaboration.

Proposals should consider the Council Recommendation of 23 May 2024 on enhancing research security 39 and take into account its principles for responsible internationalisation.

HORIZON-INFRA-2026-DEV-01-07: Risk management, mitigation and contingency for ESFRI/ERIC and other world-class research infrastructures

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 1.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 10.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 40 .

Expected Outcome: Project results are expected to contribute to several of the following expected outcomes:

1.European research infrastructures benefit from more robust risk management plans notably in the climate, biodiversity loss, pollution, health and social science domains and the risks related to access to critical data, equipment or facilities;

2.European research infrastructures have implemented mitigation plans and, where needed, contingency plans for the most critical risks such as preservation of critical data, geographical coverage, alternative methods, tools, equipment, new or strengthened collaborations;

3.EU and Member States are better informed on critical research infrastructures and critical R&I services and able to develop policy to preserve critical data, knowledge and capacities.

4.The European Research Area benefits from more information about critical research infrastructures and R&I services, and from a preserved capacity and research freedom to address its priorities and socio-economic challenges;

5.The global competitiveness and attractiveness of the European Research Area is reinforced.

Scope: This topic targets pan-European research infrastructures such as ESFRI research infrastructures 41 , ERICs 42 and other world-class research infrastructures in Europe notably in the fields of climate, health and social sciences and aims at supporting these infrastructures in implementing mitigation and contingency plans for critical risks.

Pan-European research infrastructures such as those prioritised by ESFRI, ERICs, and other world-class research infrastructures in Europe often engage in international collaboration in areas where global coverage is essential for knowledge creation, like for example climate understanding and modelling or pandemic preparedness, or where a critical mass is needed.

Proposals should involve research infrastructures that are sharing similar or related risks, which could be better addressed by common or coordinated implementation of mitigation and, where needed, contingency plans. Proposals should pay due attention to the importance of sustaining such plans beyond the project’s duration.

Proposed actions under this topic should

1.Describe capacities at risk, be it due to shrinking geographical coverage or to loss or interruption of data, limited access or expansive access fees to data, to equipment, to facilities, supply challenges (see ESFRI work 43 ) etc. and where relevant update risk management plans. Exchange best practices on risk-assessment and develop guidance.

2.Describe where applicable the expected impact of realised risks beyond the research infrastructures concerned i.e. impact on related operational or deployment programme where relevant, on international agreements, on addressing EU priorities, on EU competitiveness, on EU strategic autonomy; in this context, identify which research infrastructures services could qualify as ‘critical R&I services’.

3.Implement mitigation and, where applicable, contingency plans to address capacities at risk, in order to ensure the sustainability of the research infrastructure concerned as well as to preserve EU capacity and research freedom to address its policy, priorities and socio-economic challenges investments across Europe for trusted and secure storage, processing and sharing of critical data including through EOSC.

4.Develop guidance and disseminate best practices on risk-assessment and research security, taking into account EU recommendations in the field of research security and foreign interference. Where relevant, links to initiatives such as the development of a European centre of expertise on research security should be explored.

HORIZON-INFRA-2027-DEV-01-01: Preparatory phase of new ESFRI research infrastructure projects

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 1.50 and 3.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 30.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

If eligible for funding, legal entities established in non-associated third countries may exceptionally participate in this Coordination and support action as a beneficiary or affiliated entity.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 44 .

Expected Outcome: Projects are expected to contribute to several of the following expected outcomes:

1.Increased performance, scientific capacity and excellence of the European landscape of research infrastructures enhancing problem-solving capacities of the ERA to address challenges in science, industry and society;

2.Legal, financial and technical issues addressed, leading to long-term perspective for research infrastructure investments and the establishment of a new research infrastructure and ensuring commitment of Member States/Associated Countries to their long-term operation and use;

3.Solid ground for the decision making on new research infrastructures (or major upgrades), is available to Member States/Associated Countries, their funding bodies and other relevant stakeholders (e.g. international organisations, third countries, foundations);

4.Structuring effect on the ERA through a consistent and well-functioning European research infrastructures ecosystem through the development of synergies and complementarities between new and existing research infrastructures, and with other infrastructures such as technology infrastructures and infrastructures financed by ERDF or the Digital Europe Programme.

Scope: This topic supports the preparatory phase of new ESFRI research infrastructure projects identified in the 2026 update of the ESFRI Roadmap. These ESFRI projects have been selected for the excellence of their scientific case and for their strategic importance for the European Research Area and the structuring of the European research infrastructure ecosystem.

Proposal consortia should involve all the stakeholders necessary to move the project forward, to take the decisions, and to make financial commitments, before construction can start (including, but not limited to, national/regional ministries/governments, research councils or funding agencies from the countries that have already declared their commitment in the application to ESFRI). Operators of research facilities, research centres, universities, and industry may also be involved whenever appropriate.

Proposals for research infrastructure preparatory phases should tackle all key questions concerning legal, financial and technical issues leading to the establishment of a new research infrastructure and ensuring commitment of Member States/Associated Countries to their long-term operation and use in all fields of science.

In this respect, proposals should address all of the following aspects:

1.the development of legal and financial frameworks/plans relating to the setting-up, construction and/or integration of national resources, operation and decommissioning of the research infrastructure as well as its governance structure; the complementarities between national and EU instruments and/or innovative financing;

2.the preparation of legal and financial agreements, including site, governance, internal rules, financing of the new research infrastructures. These are deliverables that should be finalised before the end of the project (e.g.: through a Memorandum of Understanding; a 'signature-ready' document for the setting-up and the actual implementation of the research infrastructure);

3.the establishment of plans for logistics and human resources management, in relation to the construction/integration and future operation, including RI service provision as well as for an efficient data curation and preservation and for the provision of access to data collected or produced by the future infrastructure, in line with the FAIR principles;

4.the technical challenges concerning the joint development, transfer of knowledge and implementation of key RI technologies and the completion of the final technical design of the infrastructure;

5.the development of plans for the provision of RI services to identified scientific user communities;

6.the relevance of the RI for science and society, including its socio-economic impacts at local/regional level and links with the smart specialisation strategies at regional level.

Proposals should explain any synergies and complementarities with previous or current EU grants notably under the research infrastructures part of the Horizon Europe work programme.

When relevant, environmental (including climate-related) impacts as well as the optimisation of resource and energy use should be integrated in the preparatory phase of new or upgraded research infrastructures.

HORIZON-INFRA-2027-DEV-01-02: Consolidation of the research infrastructure landscape – development of complementarities, synergies and/or integration between a set of pan-European research infrastructures

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 2.00 and 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 20.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Due to the scope of this topic, proposals must include at least one of the ESFRI Landmarks 45 or European Research Infrastructure Consortia (ERICs) 46 as beneficiaries. Such beneficiaries, and the research infrastructure(s) that they operate, must be explicitly identified in the proposal. For distributed ERIC the ERIC must be the beneficiary.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 47 .

Expected Outcome: Project results are expected to contribute to several of the following expected outcomes:

1.better structured, integrated and strengthened European research infrastructure landscape;

2.solid concepts and/or comprehensive plans for the integrated research infrastructures, to support decision making at national and European level, leading to increased sustainability, operational and financial efficiency;

3.increased synergies between research infrastructures;

4.increased capacity to address EU policy priorities and/or support EU industry;

5.reinforced global competitiveness and attractiveness of the European Research Area.

Scope: This topic targets the consolidation and improved functioning of the EU RI landscape through the support to the development of complementarities, synergies and/or integration between a set (two or more) of ESFRI Landmarks and/or other European Research Infrastructure Consortia (ERICs) or, if duly justified, between one ESFRI Landmark or ERIC and other European research infrastructures of European interest 48 .

Proposals could address either a tighter operational integration between infrastructures, or instead the feasibility and the planning of a merging between infrastructures, which could be targeted in future by a specific topic. The rationale and the potential benefits of the planned consolidation action should be clearly spelled out in the proposals.

When addressing an operational integration, projects will develop complementarities and/or synergies between infrastructures, at thematic and/or cross-disciplinary level, to optimise the functioning of the RI landscape. The development of complementarities (e.g. through service level agreements for the sharing of horizontal/common services/tools, including external ones) should lead to increased efficiency and prevent unnecessary duplications. Synergies should be exploited to address complex research challenges and EU priorities and should be implemented through cooperation mechanisms ensuring sustainable and long-term integration of services and resources (e.g. common horizontal services, joint scientific services). The needed joint staff skill development, including exchange programmes among the participating RIs, could also be supported.

When addressing a merging between infrastructures, proposals should provide evidence that the project will effectively involve the funders of the different infrastructures, develop the concept of the merged infrastructure in all its dimensions, including governance, legal form and operation, and define the operational steps and the financial forecast for the actual merging process. Where relevant, pilots for the integration of services and resources (e.g. common horizontal services, joint scientific services) as well as joint staff skill development, including exchange programmes will also be supported.

Proposals should explain any synergies and complementarities with previous or current EU grants notably under the research infrastructures part of the Horizon Europe work programme 49 .

HORIZON-INFRA-2027-DEV-01-03: Consolidation of the research infrastructure landscape – individual support for evolution, long-term sustainability and emerging needs of pan-European research infrastructures

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 29.50 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Due to the scope of this topic, proposals must include at least one of the ESFRI Landmarks 50 or European Research Infrastructure Consortia (ERICs) 51 as beneficiaries. Such beneficiaries, and the research infrastructure(s) that they operate, must be explicitly identified in the proposal. For distributed ERIC the ERIC must be the beneficiary.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 52 .

The funding rate is 80% of the eligible costs.

Expected Outcome: Project results are expected to contribute to several of the following expected outcomes:

1.better structured and strengthened European research infrastructure landscape;

2.new services available to a wider user community, including participants in other parts of Horizon Europe, allowing to better tackle scientific and societal challenges;

3.increased capacity to address EU policy priorities and/or socio-economic challenges;

4.reinforced global competitiveness of the European Research Area;

5.reduction of environmental (including climate-related) impacts as well as optimisation of resource and energy consumption integrated through the full life cycle of research infrastructures;

6.increased long-term sustainability of European research infrastructures.

Scope: This topic targets the consolidation of the EU research infrastructures landscape through the support, together with the countries that are members of the research infrastructures, to the strengthening, long-term sustainability, reorientation or evolution of ESFRI Landmarks or European Research Infrastructure Consortia (ERICs).

The proposed action should justify the specific objectives and focus on activities that are critical for the sustainability and optimised use of the ESFRI Landmarks or ERICs, such as activities aiming at several of the following objectives:

1.enlargement of the membership or broadening of the base of participating countries, notably widening countries and candidate countries;

2.addressing critical aspects raised following an assessment or monitoring exercise, e.g. in the context of ESFRI activities;

3.reinforcing international cooperation;

4.revision of business/funding plan;

5.development of managerial and technical skills for research infrastructure staff;

6.structuring and strengthening of national/thematic nodes;

7.extension of remote and/or virtual access;

8.management of research data according to the FAIR principles;

9.reorientation or evolution of the research infrastructure scope;

10.development, update and or implementation of impact assessment of the research infrastructure.

In case of reorientation or evolution of the research infrastructure scope, activities should fill gaps in the research infrastructures landscape 53 , enabling the research infrastructure to address new research or societal challenges and/or serve new user communities, increasing and improving service capacity and/or integrating new resources/facilities.

Due attention must be given to related EU initiatives, strategies and priorities and, when relevant, to complementarity and relevance to activities in other parts of Horizon Europe, such as better addressing SRIAs of Horizon Europe partnerships. Proposals should explain any synergies with previous or current EU grants notably under the research infrastructures part of the Horizon Europe work programme e.g. INFRADEV and INFRATECH grants.

Given the funding rate, proposals should ensure a minimum adequate backing by the beneficiaries, who should provide the remaining share for the activities covered by the Grant Agreement and foster the sustainability of the ESFRI Landmark or ERIC.

Specific attention should be given, where relevant, to the greening of technologies and methodologies used by the research infrastructure, to the interaction with industry/SMEs, to the fostering of the innovation potential of the infrastructures, and to their integration into local, regional and global innovation ecosystems.

Destination INFRAEOSC - Enabling an operational, open and FAIR EOSC ecosystem (2026-27)

This destination serves the European Open Science Cloud (EOSC) ambition of contributing to a web of FAIR (Findable, Accessible, Interoperable, Reusable) research data and providing a trusted and secure federated system of research data and services (EOSC Federation) for researchers in the EU and Associated Countries to store, share, process and reuse within and across disciplines and borders FAIR research outputs and tools for research, innovation and educational purposes.

The expected impacts of the activities supported under this destination are in line with objectives of the co-programmed European Partnership for EOSC and its Strategic R&I Agenda 54 , in particular:

1.Enable the definition of standards, and the development of tools and services, to allow researchers to find, access, reuse and combine results;

2.Establish a sustainable and federated infrastructure enabling open sharing and reuse of scientific results;

3.Ensure that Open Science practices and skills are rewarded and taught, becoming the norm across the European Research Area.

Activities should continue to transform the research landscape in Europe by bringing cohesion and addressing common needs of the research communities. The programme should catalyse a fully operational environment covering the whole research data lifecycle across borders and communities.

To further advance this ambition, the EU must continue investing in dedicated activities and ensure synergies between EOSC-related actions at the EU, national, institutional and community levels.

All software developed under this destination should be open-source, licensed under a CC0 public domain dedication, EUPL 55 or under an open-source licence as recommended by the Free Software Foundation 56 and the Open-Source Initiative 57 .

All projects financed under this destination are expected to participate in concertation activities in the framework of the EOSC Partnership.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions and Innovation Actions falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Proposals are invited against the following topic(s):

HORIZON-INFRA-2026-01-EOSC-01: Uptake of FAIR data management practices and of EOSC by research communities and research infrastructures (EOSC Partnership)

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 40.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 40.00 million.

Type of Action

Research and Innovation Actions

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The following additions to the general award criteria apply:

For the ‘Impact’ criterion, the following aspects will also be taken into account:

The extent to which the proposed work incorporates the necessary coordination efforts and resources with other relevant projects and the European Open Science Cloud (EOSC) governance structure in the context of the EOSC Partnership.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. Given that the financial support to third parties is one of the primary aims of the action and taking into account the nature of the work to be supported and the cross-RI, cross-domain nature of the intended open science projects and services, the maximum amount to be granted to each third party is EUR 750 000. The selection of the third parties to be supported will be based on an external independent peer review of their proposed work. Research infrastructures which are beneficiaries/affiliated entities of the consortium awarded may exceptionally also be recipients of financial support to third parties. Proposals must explain how they will ensure that such beneficiaries/affiliated entities are not involved in the drafting and selection procedure of the calls, and explain measures, in order to avoid conflicts of interest and equal treatment of applicants and to maintain confidentiality.

The open calls should respect the conditions laid out in Section B of the General Annexes, including transparency, equal treatment, conflict of interest and confidentiality.

Beneficiaries will be subject to the following additional access rights: Each beneficiary must grant royalty-free access to its results to the EOSC Association for monitoring and developing policies and strategies for the European Open Science Cloud. Each beneficiary must also provide directly to the EOSC Association the information the beneficiary deems necessary for monitoring and developing policies and strategies for the European Open Science Cloud.

Beneficiaries and supported third parties must deposit the digital results generated in the action in a trusted repository federated in EOSC in compliance with EOSC requirements.

Expected Outcome:

1.Increased adoption of open science and research data management practices in line with the FAIR principles by researchers and across research infrastructures (RIs) in Europe.

2.Increased uptake of the EOSC Federation by researchers through the long-term sustainable provision in the Federation of scientific services and high-quality, FAIR research data, and their integration in scientific workflows addressing current gaps and needs of research communities.

3.Research communities, as well as ESFRI and other European research infrastructures increase their alignment with EOSC standards and policies, and their capacity to integrate in the EOSC Federation.

Scope: This topic aims to further increase across Europe the adoption of open science and research data management practices in line with the FAIR principles, and to support the development of a user-focused and science-driven EOSC Federation.

It capitalises on the previous work by Science Clusters in enabling open science practices, FAIR implementation and managing open calls for multi-disciplinary science projects. It also builds on the experience by several RIs and other organisations as active participants in building the EOSC Federation, either through the establishment of EOSC nodes or the onboarding of resources to EOSC nodes 58 , to support the engagement of underrepresented RIs and research communities into the EOSC ecosystem.

Proposals should cover both the following activities:

1) Accelerate FAIR adoption and the contribution to and use of EOSC resources by multiple research communities through open science projects.

This activity should be implemented through open calls that provide grants to third parties for open science projects through a cascading grant mechanism. The open calls should encourage, where applicable, cross-RI and/or cross-domain collaborations, including for data access, use and reuse.

Open science projects should address questions of high scientific impact, adopting best practices for FAIR data and service management and demonstrating their benefits. Their activities may include developing, annotating, curating and making FAIR high-value datasets, developing direct pipelines to integrate large-scale experimental data in repositories federated in EOSC, operationalising data access for AI-based applications, reusing existing datasets, enhancing existing and developing new vocabularies, data standards, metadata mappings and crosswalks, developing software, tools and services, or supporting open science community building.

They should cover a broad range of (academic and/or industrial) research communities and scientific disciplines, including those less represented in the EOSC Federation. They should make use of resources available in the EOSC Federation and adopt existing EOSC policies and standards 59 , where possible. Projects should strive to ensure the sustained, beyond the projects’ duration, integration, deployment and operation of relevant outcomes in the EOSC Federation.

At least EUR 29 million of the EU contribution to this topic should be used in this activity 60 . The financial support to third parties for the open science projects must be provided in the form of grants that should be between EUR 100 000 and 250 000 per grant for a duration of 12 to 24 months. The consortium shall put in place adequate measures to support the integration of the open science projects’ results into the EOSC Federation. These could include mentoring, training and any other activities providing effective linkage to the EOSC Federation and EOSC Nodes, as needed for the specific nature of each project.

2) Support the integration of thematic research and RI communities in the EOSC Federation

The following activities should be included:

1.Coordinating, aligning and networking existing community-based competence centres on FAIR and open science practices developed within the EOSC ecosystem.

2.Developing training programmes, modules and material on FAIR and open science practices tailored to the specific needs of different thematic research communities. This activity should include feedback mechanisms to ensure that the training services are responsive to the evolving needs of EOSC user communities.

3.Developing frameworks for the provision and continuous evolution of high-impact services and data repositories onboarded to the EOSC Federation, fostering interoperability and integration of data and resources from diverse scientific domains and promoting their sharing through the EOSC Federation.

4.Establishing mechanisms for the integration and long-term sustainable provision of all relevant outcomes into the EOSC Federation, as well as for continuous feedback and adaptation, ensuring evolving requirements of researchers and RIs are met within the EOSC ecosystem.

5.Engaging underrepresented thematic research and RI communities to increase their integration in EOSC.

Proposals are expected to cooperate and align with activities of the EOSC Partnership and to coordinate with relevant initiatives and projects, including actions awarded under topics HORIZON-INFRA-2025-01-EOSC-01, HORIZON-INFRA-2025-01-EOSC-02 and HORIZON-INFRA-2027-01-EOSC-01. This may include the upgrade, deployment and adoption where appropriate of existing community-endorsed pilot, tools, services and standards developed by past and ongoing INFRAEOSC projects. To this extent, proposals should provide for dedicated activities and earmark appropriate resources.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement. This topic implements the co-programmed European Partnership for the European Open Science Cloud 61 .

HORIZON-INFRA-2026-01-EOSC-02: Trusted frameworks for secure and efficient data sharing in EOSC (EOSC Partnership)

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 10.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The following additions to the general award criteria apply:

For the ‘Impact’ criterion, the following aspects will also be taken into account:

The extent to which the proposed work incorporates the necessary coordination efforts and resources with other relevant projects and the European Open Science Cloud (EOSC) governance structure in the context of the EOSC Partnership.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries will be subject to the following additional access rights:

1.Each beneficiary must grant royalty-free access to its results to the EOSC Association for monitoring and developing policies and strategies for the European Open Science Cloud. Each beneficiary must also provide directly to the EOSC Association the information the beneficiary deems necessary for monitoring and developing policies and strategies for the European Open Science Cloud.

2.Each beneficiary must grant royalty-free access to its intellectual property rights which are part of the results and are needed for further developing the European Open Science Cloud to legal entities identified by the granting authority and established in Member States or countries associated to the Horizon Europe Framework Programme. Such access rights are limited to non- commercial use.

Beneficiaries must deposit the digital research data generated in the action in a trusted repository federated in the European Open Science Cloud (EOSC) in compliance with EOSC requirements.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 62

Expected Outcome: Project results are expected to contribute to the following outcomes:

1.Countries, research communities and institutions are equipped with data sovereignty frameworks harmonised within EOSC and aligned with EU legislation and international agreements.

2.Improved mechanisms and solutions for effective control over sensitive data and for enabling lawful data use and sharing across EU member states, scientific disciplines and third countries with EU adequacy decision in place.

3.More harmonised guidelines, support and training to researchers and data stewards on applying EU and national legislation and international agreements for data access, sharing, reuse, licensing and associated services within EOSC.

4.Increased interoperability with relevant solutions of other European data spaces for secure data management and processing.

Scope: Research data sovereignty refers to the possibility for effective control by data owners of data usage and sharing when necessary. Effective and transparent community-driven data sovereignty frameworks are important enablers of open science, in particular ensuring safe and trusted management of personal or sensitive data, safeguarding the quality of curated research datasets and the effective application of related EU and national digital and data legislation. Data sovereignty mechanisms can also improve the resilience and preparedness of research and data infrastructures against risks related to access to and preservation of critical data and services, including risks related to data generated and stored outside the EU/EEA.

The exponential growth of available research data and the increasingly collaborative and cross-disciplinary research has accentuated challenges related to secure, efficient and lawful cross-border data sharing for research purposes. Removing barriers to data sharing while ensuring data sovereignty is crucial to realise the potential of EOSC to foster trusted cross-country and cross-discipline scientific collaboration.

This topic aims to support data sovereignty while enabling seamless and trusted data sharing and access across scientific disciplines, EU Member States and third countries where the EU considers sufficient data protection is in place, tackling different regulatory regimes and procedures.

Proposals should include the following activities:

1.Development and implementation of national, community and/or institutional research data sovereignty frameworks, including policies for data sharing and access, harmonised and aligned with EU digital and data legislation and international agreements such as adequacy decisions and digital partnership agreements, as well as best practices from EOSC, related common European data spaces and international data-sharing standards and initiatives.

2.Demonstration and validation of concrete adoption cases of data sovereignty policies by national, community or institutional actors, aligned with open science and the FAIR data principles.

3.Development of harmonised governance frameworks, ensuring smooth enforcement of data sovereignty policies.

4.Development of comprehensive data provenance tools to trace and verify the quality and lineage of data used in research, and demonstration through identified use cases within relevant selected thematic areas.

5.Development of templates and guidelines for secure and sovereign data management, including template agreements on data sharing, publication, and reuse, and guidelines for licensing.

6.Development of guidelines for classifying critical data and services based on sensitivity and relevance to scientific communities and European policies, and for managing risks related to access to and preservation of such critical data and services.

7.Analysis of data categories and definitions across scientific disciplines, incorporating compliance with security requirements set out in EU and national legislation.

8.Development of recommendations for the establishment of a support centre, linking with relevant national and thematic competence centres, focused on compliance of data management with EU and national legislation, and proof of concept of its integration and sustainable operation in the EOSC Federation.

Projects are encouraged to explore synergies with relevant EU initiatives such as other common European data spaces that address sensitive data or data critical for research. To ensure complementarity and use of latest research results, proposals should build on ongoing and previous INFRAEOSC projects such as those funded by topics 2023-EOSC-01-06, 2023-EOSC-01-04 and 2024-EOSC-01-04 and align with the EOSC Federation policies and standards 63 . This topic implements the co-programmed European Partnership for the European Open Science Cloud 64 .

HORIZON-INFRA-2027-01-EOSC-01: Expanding and deepening the EOSC Federation (EOSC Partnership)

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 40.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 40.00 million.

Type of Action

Programme Co-fund Action

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The following additions to the general award criteria apply:

For the ‘Impact’ criterion, the following aspects will also be taken into account:

The extent to which the proposed work incorporates the necessary coordination efforts and resources with other relevant projects and the European Open Science Cloud (EOSC) governance structure in the context of the EOSC Partnership.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. Financial support provided by the participants to third parties is the primary activity of the action in order to be able to achieve its objectives. Given the type of action and its level of ambition, as well as that access to certain types of digital services can be costly and that activities other than access will also be supported, the maximum amount to be granted to each third party is EUR 2.00 million.

The funding rate is 50% of the eligible costs. This is justified as the provision of digital services to users of the EOSC Federation and the broadening and integration of research communities in the EOSC Federation are activities with strong European added value that are typically not supported by national funding bodies.

At least 20% of the total financial support to third parties must be open to entities eligible for funding as described in the General Annex B, therefore it must not have any additional geographic restrictions for eligibility for funding.

Beneficiaries will be subject to the following additional access rights:

1.Each beneficiary must grant royalty-free access to its results to the EOSC Association for monitoring and developing policies and strategies for the European Open Science Cloud. Each beneficiary must also provide directly to the EOSC Association the information the beneficiary deems necessary for monitoring and developing policies and strategies for the EOSC.

2.Each beneficiary must grant royalty-free access to its intellectual property rights which are part of the results and are needed for further developing the EOSC to legal entities identified by the granting authority and established in Member States or countries associated to the Horizon Europe Framework Programme. Such access rights are limited to non- commercial use.

Expected Outcome: Project results are expected to contribute to the following outcomes:

1.The EOSC Federation provides to EOSC users with state-of-the-art digital services addressing their needs to store, process and share data, run software, models and workflows, and collaborate with their peers.

2.Research and digital infrastructures and other organisations providing scientific services are equipped with appropriate structures and technical, legal and coordination mechanisms to onboard, manage and sustainably operate digital tools and services in the EOSC Federation.

3.Investments across Europe in the provision of FAIR scientific data and services within EOSC are more aligned and coordinated, achieving economies of scale and more efficient use of digital resources.

Scope: In order to carry out typical research workflows, researchers need to use a broad range of digital services such as data storage, computing, applications, and collaboration tools. Such services are often cost-intensive and their provision is restricted, e.g. to researchers within a country/region or a specific thematic area. The EOSC Federation aims to provide a trusted, sovereign and secure environment to researchers in Europe to use high-quality, FAIR research data and run research workflows, with a focus on cross-disciplinary and cross-country research collaboration.

The aim of the topic is to set up an EOSC Federation-wide mechanism that enables multiple organisations to seamlessly offer such digital services, and to support the sustained provision of these services to EOSC users. It also aims to enlarge the EOSC Federation by supporting the expansion of Nodes as gateways through which multiple organisations can offer their resources, such as data and services, to EOSC users.

Proposals should cover the following activities:

1) Provide seamless, user-friendly access to EOSC users to digital services for typical research workflows such as data storage, computing, applications, and collaboration tools, through a fully integrated EOSC Federation-wide system.

1.Gather requirements and analyse needs of researchers and EOSC users for such services and how they can best complement and integrate with existing resources in the EOSC Federation.

2.Support developing and embedding a Federation-wide resource management and accounting system for the efficient provision of such services across the Federation, building on the design principles of the ‘virtual credit allocation’ system of the EOSC EU Node and any further development in the EOSC Federation.

3.Provide access to EOSC users to such services, based on the researchers' and EOSC users' needs and requirements and making use of a Federation-wide resource management and accounting system and harmonised access policies, in line with the principles and guidelines of transnational and virtual access to European Research Infrastructures and related EOSC Federation policies.

4.Upgrade the EOSC user experience through deep, back-end, cross-provider integration of key digital services covering the full research lifecycle, achieving a user-friendly and robust environment.

5.Develop, test and demonstrate business models for the effective management of the supply and demand of such services, as well as for their long-term sustainable provision in the EOSC Federation, beyond the end of the project’s duration.

6.Develop guidelines to facilitate a harmonised approach to the acquisition and provision of such services that supports research data sovereignty and research security in Europe, ensuring a trusted, secure and sovereign EOSC Federation.

7.Establish mechanisms for continuous feedback and improvement, including indicators for monitoring the quality and usage of the services, building on and further developing existing mechanisms of the EOSC Federation, and ensuring that the evolving needs and requirements of EOSC users are met by the EOSC Federation.

These activities should be fully concerted and aligned with related parallel activities carried out by the EOSC Federation.

2) Support the broadening, integration and structuring of the participation of research communities in the EOSC Federation through

1.the development and establishment of intra-Node coordination mechanisms and organisational models to enable EOSC Nodes to effectively represent broad communities and multiple organisations in the EOSC Federation,

2.the development and use of digital capabilities, and of options for harmonised legal arrangements, such as contractual or service-level agreements, for onboarding and sustainably provisioning communities’ services through EOSC Nodes,

3.broadening organisations’ engagement with and contribution to the EOSC Federation, including underrepresented thematic research communities or geographic areas.

Proposals should implement the activities through the organisation of joint calls that provide grants to third parties.

The joint calls should be open to organisations that participate or are interested to participate in the EOSC Federation either by operating an EOSC Node or by onboarding their identified resources to the EOSC Federation, in line with the relevant criteria set by the EOSC Federation.

Proposed activities should be driven by current gaps and needs of scientific communities, digital infrastructures and service providers. Proposals should clearly demonstrate how they will contribute to addressing these needs and increasing the uptake of the EOSC Federation by researchers.

The activities should comply with and contribute to the continuous update and upgrade of related EOSC Federation policies and standards, including technical and interoperability standards, the use of open standards, harmonised access and use policies, and cybersecurity 65 .

Proposals should include a robust and credible plan for the long-term, beyond the project’s duration, sustained operation of the services that they will make available in the EOSC Federation, and any other relevant project results.

For what concerns provision of access to digital services by third parties funded under the joint calls, proposals should include a list of the digital services that will be supported through the joint calls. The third parties funded under the joint calls should identify the specific digital services that they will provide for access and the amount of access made available to EOSC users, allocating budget according to users’ demand and making use of the Federation-wide resource management and accounting system. These third parties should also fulfil further conditions and requirements described in the ‘Virtual Access Activities’ part of the ‘Specific Features for Research Infrastructures’ section of this Work Programme, for what concerns publicity of the access offered, determining the access costs, and setting criteria for access by EOSC users in line with the EOSC Federation access policies. Proposals are expected to address compliance with these specific conditions and notably ensure that the selected third parties will provide appropriate documentation to support and justify the amount of access provided and corresponding costs.

Projects are encouraged to explore synergies with relevant EU initiatives such as EuroHPC. To ensure coherence and complementarity of outcomes, funded projects are expected to cooperate with each other and with relevant initiatives and projects contributing to the development of the EOSC Federation including actions awarded under the topics HORIZON-INFRA-2023-01-EOSC-04, HORIZON-INFRA-2024-EOSC-02-01, HORIZON-INFRA-2025-01-EOSC-01, HORIZON-INFRA-2026-01-EOSC-01 and closely interact with the organisational setup of the EOSC Federation. To this extent, proposals should provide for dedicated activities and earmark appropriate resources. This topic implements the co-programmed European Partnership for the European Open Science Cloud 66 .

HORIZON-INFRA-2027-01-EOSC-02: Strengthening the potential of the EOSC for knowledge valorisation and industry-academia collaboration (EOSC Partnership)

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 2.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Coordination and Support Actions

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The following additions to the general award criteria apply:

For the ‘Impact’ criterion, the following aspects will also be taken into account:

The extent to which the proposed work incorporates the necessary coordination efforts and resources with other relevant projects and the European Open Science Cloud (EOSC) governance structure in the context of the EOSC Partnership.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries will be subject to the following additional access rights:

1.Each beneficiary must grant royalty-free access to its results to the EOSC Association for monitoring and developing policies and strategies for the European Open Science Cloud. Each beneficiary must also provide directly to the EOSC Association the information the beneficiary deems necessary for monitoring and developing policies and strategies for the European Open Science Cloud.

2.Each beneficiary must grant royalty-free access to its intellectual property rights which are part of the results and are needed for further developing the European Open Science Cloud to legal entities identified by the granting authority and established in Member States or countries associated to the Horizon Europe Framework Programme. Such access rights are limited to non- commercial use.

Beneficiaries must deposit the digital research data generated in the action in a trusted repository federated in the European Open Science Cloud (EOSC) in compliance with EOSC requirements.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 67 .

Expected Outcome: Project results are expected to contribute to the following outcomes:

1.Better overview of the identified opportunities and barriers of the EU’s current legal framework on intellectual property (patents, copyright, licenses etc.) for researchers to valorise knowledge resources provided and/or processed in the EOSC Federation.

2.Organisations contributing resources to the EOSC Federation have improved capacity, stronger incentives and better legal and technical conditions to valorise these knowledge resources and engage in open innovation practices and industry-academia collaboration.

3.Organisations contributing to the EOSC Federation have clearer frameworks and incentives to offer their resources to innovators, deep-tech startups and startups emerging from academia.

4.Organisations contributing to the EOSC Federation have established channels in EOSC to promote knowledge valorisation with the private sector, including SMEs and industry.

Scope: This topic aims to support increasing and exploiting the potential of EOSC as a driver of innovation and a platform for researchers to develop new technologies and solutions that can be brought to the market.

Knowledge valorisation is one of the EU’s key priorities for the European Research Area, aiming to ensure that the increasing amount of research results generated in the EU, mostly with full or partial public funding, are transformed to products, services and solutions that benefit society and contribute to economic competitiveness.

Many initiatives have already been taken at EU level to boost knowledge valorisation, including the guiding principles, codes of practice and a platform to build a community to share experiences 68 .

The EOSC Federation brings together and makes available to researchers, large volumes of knowledge resources, including data, publications, software, tools and services from different research and data infrastructures and scientific services providers across Europe. It therefore has the potential to facilitate and provide appropriate frameworks for knowledge valorisation, open innovation practices and industry-academia collaboration especially for what concerns results that stem from cross-discipline or cross-country research. Activities funded under this topic should aim to support the capacity of the EOSC Federation and its community to better valorise research results in line with the EU’s code of practice on intellectual assets management 69 and standardisation in the European Research Area 70 .

A key element in this effort is to clarify the legal conditions to valorise knowledge resources, including resources provided in the EOSC Federation. As knowledge resources have various degrees of copyright protection, it is often challenging for researchers to navigate in what they are allowed to do with the knowledge resources and how they can be used in industry-academia collaboration. A better overview of requirements and more legal clarity will therefore incentivise researchers to valorise the knowledge resources of the EOSC Federation.

This effort should also take into account the specific needs of different research communities contributing to the EOSC Federation, ensuring they have the possibility to set better legal terms for knowledge valorisation through appropriate choice of licenses etc. More guidance is therefore needed to ensure that contributors can share their knowledge resources in the EOSC Federation with fewer legal strings attached.

Proposals under this topic should include the following activities:

1.Analyse opportunities and barriers emerging from the provisions of the EU’s current legal framework on intellectual property and relevant types of licenses that set the legal conditions for researchers to valorise knowledge resources in EOSC Federation.

2.Gather requirements and needs, develop and analyse potential business models and access schemes for innovators and start-ups in Europe to access and use resources available in the EOSC Federation.

3.Develop a number of case studies of identified EOSC stakeholders valorising their results and/or establishing collaboration links with the private sector.

4.Map out and evaluate the possibilities of relevant types of licenses for knowledge resources to facilitate knowledge valorisation and engage in open innovation and industry-academia collaboration.

5.Organise workshops, webinars and awareness-raising campaigns, and develop guiding material targeted at EOSC users and communities contributing to EOSC on how to facilitate and engage in knowledge valorisation and industry-academia collaboration based on the knowledge resources of EOSC Federation.

6.Develop recommendations and best practices, based also on the case studies, for further development of the EOSC Federation to facilitate knowledge valorisation and industry-academia collaboration.

To ensure complementarity with and use of the latest EU guidelines and research results, proposals should build on ongoing and previous Horizon Europe-funded projects, including IP4OS, EU guiding principles for knowledge valorisation, Knowledge Valorisation Platform and code of practice for intellectual property management and standards. This topic implements the co-programmed European Partnership for the European Open Science Cloud 71 .

Destination INFRASERV - Research infrastructures services to support a healthier future, a global climate and energy vision, a circular and resilient economy, and to advance frontier knowledge (2026-27)

EU supported transnational access to research infrastructures has radically transformed the availability of state-of-the-art facilities for researchers, reinforcing Europe’s strong research performance. Horizon Europe marked a shift towards new types of transnational access grants, awarded to consortia of diverse types of facilities providing access to broad portfolios of installations and scientific services relevant for a large research domain or in support of societal challenge and EU priorities.

Actions under this destination are invited to facilitate a fast-track access for Ukrainian researchers and innovators from government-controlled territories, through specific outreach activities, support in preparing applications to the access calls, selection priority at equal scientific merit, as well as extended ad-hoc training and duration of visits (beyond 3 months).

The expected impact of the activities supported under this destination notably includes:

1.Large scale test for a step change in EU transnational access policy in the future, from a short-term project-based approach towards a more integrated, longer-term and cross domain EU access scheme, promoting the vision of a ‘one-stop-shop’ for access to research infrastructures, their services and resources.

2.Effective access of European researchers and innovators to the best research infrastructure services from national and pan- European research infrastructures (such as ESFRI Projects and Landmarks, ERICs), while ensuring both curiosity-driven and challenge-driven access, considering also that challenge-driven access must notably foster the role of research infrastructures in greening society and improving its resilience to crises.

3.Improved research infrastructure services to address evolving scientific and societal challenges, including those related to EU priorities, and to reinforce the excellence, attractiveness and competitive edge of the ERA and its capacity to address future challenges and priorities, including through interdisciplinarity and cross-domain collaboration.

4.Improved transnational access to new users such as early-stage career researchers, and researchers and innovators from other fields or sectors, while making sure that these new activities do not come at the cost of already overbooked transnational access services.

5.New discoveries and knowledge breakthroughs enabled by access provision to the best and in some cases unique state-of-the-art RIs.

6.A new generation of researchers trained to optimally exploit all the essential and advanced tools for their research.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions and Innovation Actions falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Proposals are invited against the following topic(s):

HORIZON-INFRA-2026-SERV-01-01: Implementing digital services to empower neuroscience research for health and brain inspired technology via EBRAINS

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 32.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 32.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

The page limit of the application is 100 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

Given the specific nature of this topic, access provision activities must be included in the proposal. Please read carefully the provisions under the section “Specific features for Research Infrastructures” of this work programme part before preparing your application.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The following additions to the general award criteria apply:

For the 'Excellence' criterion, the additional following aspects will also be taken into account:

1.The extent to which the access activities (trans-national and/or virtual access) will offer access to the state-of-the-art infrastructures of European interest in the field, high quality services, and will enable users to conduct excellent research.

2.The extent to which the project will contribute to facilitating and integrating the access procedures, to improve the services the infrastructures provide and to further develop their on-line services.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs may take form of unit costs for trans-national and virtual access to research infrastructures as defined in the Decision authorising the use of unit costs for the actions involving trans-national and virtual access (see Annex 2a of the Horizon Europe Model Grant Agreement).

Expected Outcome:

1.A state-of-the-art EBRAINS digital infrastructure for brain research, providing data, digital tools and services to the European research communities in neurosciences, brain medicine, and brain-inspired technologies. The platform will be powered by AI and will integrate innovative AI tools to support intuitive interaction with users, facilitate brain research, data analysis, simulations and modelling of the brain, and support FAIR data indexing and archival to scale-up data integration and curation.

2.New services and applications for neuroscience, brain health and cognitive technologies, aligned with national and European research priorities. Workflows that connect and integrate large sets of data, services and tools available at EBRAINS will be in the focus in combination with access to large storage and compute resources.

3.Innovative brain-inspired AI tools, that are based on insights from brain research, for example, in learning, decision process, plasticity, with application in research, robotics, and neurotech.

4.Detailed, data-driven, multi-scale models of complex behaviour, intelligence, consciousness and language, to study the role of variability in human brain organization during the lifespan, under different conditions.

5.Digital brain twins and/or body twins, informed by real-life sensor data, to assist the development of new digital tools for brain medicine, e.g., for diagnostics, rehabilitation, intensive care and surgery.

6.A framework for the European Brain Data Space, aligned with the European Health Data Space, in connection to EOSC and linked with common European data spaces in the life science and health sector, to support collaborative digital neuroscience and reproducible brain science, and to bridge basic and clinical research in the context of the European partnership for brain health.

7.Strengthened European cooperation advancing brain health research to ensure streamlined efforts, avoiding duplication while maximizing impact particularly in the context of the European Partnership for Brain Health through shared infrastructure, leading to improved diagnostics, innovative therapies, and more personalized treatment plans, ultimately enhancing patient care and public health.

EBRAINS is an integrative, distributed digital research infrastructure (RI) of pan-European relevance, developed under the EU-funded Human Brain Project (HBP), to cross-fertilise progress in neuroscience, medicine and advanced computing including AI. While since 2021 EBRAINS is included in the ESFRI roadmap, EBRAINS continues developing as the reference RI for digital neuroscience to help reach a deeper understanding of the human brain and to catalyse new findings in science, and innovative brain-inspired technologies and computing. Furthermore, EBRAINS, as part of the upcoming European Partnership for Brain Health, will facilitate medical innovation providing value added services and access to world-class EU HPC resources to a wide community of professionals, including clinicians, neuro- and computer scientists. Importantly, EBRAINS has potential to contribute to the novel EuroHPC AI Factories and the planned AI Gigafactories, fostering the translation of insights from neuroscience for novel AI, neuro-inspired computing and neurorobotics into business and industry.

Scope: The scope of this topic is to support the excellence and attractiveness of the EBRAINS Research Infrastructure by operating existing, improved and new services, advancing scientific and technological discoveries in neurosciences, brain medicine and brain-inspired cognitive technologies, and attracting a wide community of users, including industrial users.

Proposals are expected to address all following activities:

1.Operate the EBRAINS research infrastructure digital facilities, providing access to a federated supercomputing RI, large data storage, computational capabilities and cloud services, with access to the European HPC capacities towards exascale, and AI Factories and future AI Gigafactories.

2.Support the use of EBRAINS digital services by researchers across Europe. Support the development of services involving scientific, medical and industrial stakeholders via co-design approach, including the integration of new data and services from new users and/or EBRAINS national competence nodes, enriching the cloud-based deliveries and facilitating the sharing of produced data and use of national resources.

3.Integrate AI tools in EBRAINS services to support intuitive interaction with users, to facilitate brain research, neuroscience data analysis, simulations and biological modelling of the brain, and to support FAIR data indexing and archival to scale-up data integration. This includes developing new foundational models dedicated to the field of neuroscience. The unique multi-scale database with data from the micro to the macro scale hosted by EBRAINS would be one of the essential resources for feeding these models.

4.Demonstrate scalability and robustness of the approaches, both technically and operationally. This includes the ability to handle large and complex datasets (e.g., imaging data in the range of terabytes) including associated metadata; the provision of scalable tools and services (e.g., annotation platforms, AI pipelines, secure data handling) that go beyond limited pilot phases or academic prototypes; a clear plan for how the infrastructure or platform proposed will evolve into a robust and continuously available service that can meet the needs of real-world users, including SMEs and clinical stakeholders.

5.Develop and integrate in EBRAINS a new collaborative platform for advancing and testing neuro-inspired AI to facilitate brain research, medicine and brain inspired technology, assuring interoperability with other initiatives in the field, and enabling access to strategic brain data.

6.Strengthen and build new international collaborations to support digital neuroscience as a global challenge, to ensure that Europe remains at the centre of the global efforts aimed at better understanding the brain, partnering with other main players in the International Brain Initiative, and other initiatives.

7.Develop tailored and inclusive training and skills development programmes to facilitate users access, assisting them in their digital experiments and contributing to educating a new generation of scientists and developers at the intersection of neuroscience, computing and AI.

Proposals are expected to outline how they will contribute to and align with European efforts on health data sharing, particularly in the context of the forthcoming European Health Data Space. This includes implementing FAIR data principles and mechanisms to support data discoverability, accessibility, interoperability, and reusability, and addressing how the infrastructure will support real-time or near-real-time data flows, including handling of metadata, harmonisation of data formats, and secure access for authorised users.

Proposals are expected to identify and build on synergies with other EU Research Infrastructures such as eBRAIN-Health, EUCAIM, Euro-BioImaging, TEF-Health, and other relevant infrastructures supported under Horizon Europe or previous framework programmes, ensuring sustainability, complementarity and coherence at the European level. Collaborations with relevant infrastructures should address technical and semantic interoperability to avoid further fragmentation, sharing tools, standards, and governance models, and will contribute to the broader European ambition of creating a federated, harmonised, and innovation-enabling health data ecosystem.

HORIZON-INFRA-2027-SERV-01-01: Access to research infrastructures, their resources and services: large-scale pilots for more integrated scheme across (sub)domains

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 35.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 105.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants are not required to include in their proposal a plan for the exploitation and dissemination of the results as the main objective of these actions is the service provision.

The page limit of the application is 100 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Given the specific nature of this topic, access provision activities must be included in the proposal. Please read carefully the provisions under the section “Specific features for Research Infrastructures” of this work programme part before preparing your application.

Considering the Union’s interest to make accessible to its researchers the most advanced research infrastructures, wherever they are in the world, legal entities established in Australia, Brazil, Canada, Chile, India, Japan, Mexico, New Zealand, Republic of Korea, Singapore, and USA, which provide, under the grant, access to their state-of-the-art research infrastructures to researchers from Member States and Associated Countries, are exceptionally eligible for funding from the Union under this topic.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

For the 'Excellence' criterion, the additional following aspects will also be taken into account:

1.The extent to which the access activities (trans-national and/or virtual access) will offer access to the state-of-the-art infrastructures of European interest in the field, high quality services, and will enable users to conduct excellent research.

2.The extent to which the project will contribute to facilitating and integrating the access procedures, to improve the services the infrastructures provide and to further develop their on-line services.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering the different areas, grants will be awarded to applications not only in order of ranking but at least also to those proposals that are the highest ranked within each area, provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs may take form of unit costs for trans-national and virtual access to research infrastructures as defined in the Decision authorising the use of unit costs for the actions involving trans-national and virtual access (see Annex 2a of the Horizon Europe Model Grant Agreement).

Beneficiaries could provide financial support to third parties (FSTP). The support to third parties can only be provided in the form of grants. Given the high operating costs of some state-of-the-art research infrastructures, the maximum amount to be granted to each third party is EUR 300 000, since the objectives of the action cannot be achieved otherwise. For the sake of efficiency, the FSTP calls can be combined with the calls for the access provision activities (see provisions under the section “Specific features for Research Infrastructures” of this work programme part).

Beneficiaries will be subject to the additional access rights: beneficiaries shall grant royalty-free access to their intellectual property relating to tools, standards, specifications, and other relevant outputs generated by this action to the EU institutions and to the beneficiaries of projects funded by the EU in view of a more sustained and integrated EU access scheme. This access shall be provided through a mechanism to be defined in the proposal, during and beyond the lifespan of the Grant Agreement.

Expected Outcome: Project results are expected to contribute to all the following expected outcomes:

1.More efficient access to the best research infrastructures available to researchers and innovators to conduct basic and applied research and foster innovation, irrespective of location. A single-entry point access portal, integrated or interoperable catalogues of services and converging access conditions and selection procedures;

2.A step towards a longer-term sustainable access programme harmonised across different ESFRI domains;

3.Breakthrough and leading-edge research enabled by advanced research infrastructure services, including from emerging facilities, made available to a wider user community, including in emerging areas of research;

4.A new generation of researchers trained to optimally exploit all the essential tools for their research with due attention to early-stage career researchers and researchers from widening countries and candidate countries;

5.Interdisciplinarity and sharing of information, knowledge and technologies across scientific fields with due attention to research security; better management, including implementing FAIR data principles, of the continuous flow of data collected or produced by research infrastructures.

Scope: This topic aims at testing ‘access programme like’ projects providing trans-national access (on-site or remote) and/or virtual access to integrated and customised research infrastructure installations and services for excellent research, from frontier and curiosity-driven to applied research, offered by a wide range of complementary and interdisciplinary research infrastructures with experience in transnational access. Access is provided by a core of state-of-the-art research infrastructures as beneficiaries/affiliated entities and by third party access providers on demand. Proposals should adhere to the guidelines and principles of the European Charter for Access to Research Infrastructures 72 . Proposals are expected to address one of the following areas, based on ‘ESFRI scientific domains 73 , and must explicitly state which area they address:

Area 1, covering the following domains: Physical Sciences and Engineering; Data, Computing and Digital Research Infrastructures

Area 2, covering the following domains: Health & Food; Social Sciences and Humanities

Area 3, covering the following domains: Environment; Energy.

These areas define in which pilot project a research infrastructure identified as a core access provider should be a beneficiary/affiliated entity. On demand third party access providers should expand access opportunities within the area or across-areas for interdisciplinary research.

Proposals should make available to researchers and innovators a wide, inclusive and comprehensive portfolio of complementary research infrastructure services of European interest 74 , including data services. Proposals should include at least two ESFRI Landmark 75 and/or European Research Infrastructure Consortium (ERIC) 76 as beneficiary. Access could also be open, in accordance with the ‘Specific Features for Research Infrastructure’ section of this Work Programme, to third countries’ researchers. Research infrastructures from third countries may be involved as beneficiaries or affiliated entities 77 when appropriate, if the proposal can demonstrate they offer complementary or more advanced services than those available in the EU Member States and Associated Countries.

Access includes ad hoc users’ training and scientific and technical support (see Specific Features for Research Infrastructures). Additional training courses, including skills for data stewardship, may also be supported. In addition, proposals should better exploit the training potential of successful transnational access user projects by inviting researchers, notably early-stage career researchers, or research infrastructure technicians from widening and candidate countries to team up with selected user groups. Proposals should reserve sufficient resources for this purpose and should proactively advertise these opportunities. (which should be arranged after the selection of user projects and have no impact on their evaluation).

Access provision to existing services should be clear in the proposed activities and reflected in the allocated resources.

The improvement and development of services can also be supported, provided that the resulting services are offered already under the actions (short-term R&D) and that the long-term sustainability of such services is ensured.

Data management (and related ethics issues), interoperability, as well as the connection of digital services (e.g. data services) to the European Open Science Cloud, should be addressed where relevant. Proposals should take due account of major European or international initiatives relevant in the domain. When appropriate, they should foster the use and deployment of (open) global standards.

Proposals should include an outreach and engagement plan to actively advertise their services to the research communities, notably from widening countries and candidate countries and to relevant industries, including SMEs and, if applicable, provide dedicated support for the development of research partnerships and collaborations with researchers from widening countries and candidate countries. Proposals are expected to exploit synergies and to ensure complementarity and coherence with other EU grants supporting access provision.

Proposals should include the list of core services/installations 78 opened by research infrastructures for transnational or virtual access and the amounts of units of access made available for users. Further conditions and requirements relating to access provisions that applicants should fulfil when drafting a proposal are given in the “Specific features for Research Infrastructures” section of this work programme part. Compliance with these provisions will be taken into account during evaluation.

Proposals should also present an indicative list of complementary services/installations opened by third party research infrastructures for transnational or virtual access. Proposals should reserve sufficient resources for access notably to these services/installations and allocate budget according to the demand after peer-review evaluation of the user-groups and users’ research and innovation projects, the ‘user projects’. This complementary part of the access to research infrastructures may be implemented through the mechanism of financial support to third parties (FSTP), provided that the beneficiaries ensure that the conditions and requirements relating to access provisions as given in the “Specific features for Research Infrastructures” are fulfilled. In such case, the relevant conditions and requirements should be included in the FSTP calls and the applicants to the FSTP open calls should be the third party research infrastructures demanded by user-group(s). In the case of transnational access, the beneficiaries select the user-groups according to the conditions and requirements of the “specific features for research infrastructures” section of this work programme. The beneficiaries ensure that the access provider selected through the FSTP calls is a state-of-the-art research infrastructure, and that it will provide appropriate documentation to support and justify the amount of access provided and the information on the users as specified in the “specific features for research infrastructures” section of this work programme. To simplify the selection process, proposals under this topic may combine the calls inviting researchers to apply for transnational access and the FSTP calls so that a one stage selection procedure can be implemented based on a joint application from the user group submitting the ‘user project’ and the needed third party access provider. The recipient of the financial support is the third party research infrastructure that is providing access to the selected user-group(s). The financial support should cover the costs incurred by the third party to provide access (actual costs, unit costs, or a combination of the two) plus any work for service customisation as well as the travel and subsistence of users if visits are needed to use the infrastructures. Alternatively, proposals may opt for centrally managed travel and or subsistence costs for all or part of the selected user projects. In such case, these costs are excluded from the concerned FSTP.

Access opportunities should be presented in a single-entry point portal for each pilot, building on the experience of past EU projects supporting access in the respective areas. The interoperability and capacity to converge into a common portal should be considered when designing or upgrading the portals as well as the possible connection to EOSC.

To ensure a holistic view from design to implementation of possible access schemes, proposals should ensure strong and continuous collaboration with the cross-domain preparatory action on access HORIZON-INFRA-2025-01-DEV-05 79 , with the pilots under topic HORIZON-INFRA-2026-01-DEV-02, e.g. making use of the catalogues of services, navigation tool and links to key EU initiatives, and with the actions supported under topic HORIZON-INFRA-2027-01-SERV-02. This collaboration should ensure a common front page to all above actions, set up by one of the pilots, providing at the minimum basic information such as highlighting the common objectives of EU supported access, the main conditions and requirements, providing preliminary guidance on access opportunities and directing to the single-entry point portal of each pilot. The collaboration should also promote simplified access pathways, good practices on call conditions, converging access modalities and selection process, as well as effective governance of the set of projects acting as an access programme with appropriate advisory bodies.

Proposals could consider the inclusion of the European Commission's Joint Research Centre (JRC) in any of the three areas identified in the call. The JRC is running the “open access to JRC research infrastructures” programme, providing since 2017 access and training and capacity building to a portfolio of 18 different facilities to more than 650 users from 250 institutions in Europe. In this respect, the experience of the JRC in transnational access can be very valuable for exploring new ways of creating large thematic clusters of pan-European research infrastructures. In that respect, the JRC will consider collaborating with any successful proposal and this collaboration, when relevant, should be established after the proposal’s approval.

The integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement. However, where applicable, proposals should promote in their calls for access the integration of the gender dimension in the research and innovation content of the users applying to these calls.

HORIZON-INFRA-2027-SERV-01-02: Access to research infrastructure services to enable R&I addressing EU priorities and emerging challenges

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 6.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 35.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants are not required to include in their proposal a plan for the exploitation and dissemination of the results as the main objective of these actions is the service provision.

The page limit of the application is 100 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Given the specific nature of this topic, access provision activities must be included in the proposal. Please read carefully the provisions under the section “Specific features for Research Infrastructures” of this work programme part before preparing your application.

Considering the Union’s interest to make accessible to its researchers the most advanced research infrastructures, wherever they are in the world, legal entities established in Australia, Brazil, Canada, Chile, India, Japan, Mexico, New Zealand, Republic of Korea, Singapore, and USA, which provide, under the grant, access to their state-of-the-art research infrastructures to researchers from Member States and Associated Countries, are exceptionally eligible for funding from the Union under this topic.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The following additions to the general award criteria apply:

For the 'Excellence' criterion, the following aspects will also be taken into account:

The extent to which the access activities (trans-national and/or virtual access) will offer access to the state-of-the-art infrastructures of European interest in the field, high quality services, and will enable users to conduct excellent research.

The extent to which the project will contribute to facilitating and integrating the access procedures, to improve the services the infrastructures provide and to further develop their on-line services

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering the different areas, grants will be awarded to applications not only in order of ranking but at least also to those proposals that are the highest ranked within each area, provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries will be subject to the additional access rights: Beneficiaries shall grant royalty-free access to their intellectual property relating to tools, standards, specifications, and other relevant outputs generated by this action to the EU institutions and to the beneficiaries of projects funded by the EU in view of a more sustained and integrated EU access scheme. This access shall be provided through a mechanism to be defined in the proposal, during and beyond the lifespan of the Grant Agreement.

Eligible costs may take form of unit costs for trans-national and virtual access to research infrastructures as defined in the Decision authorising the use of unit costs for the actions involving trans-national and virtual access (see Annex 2a of the Horizon Europe Model Grant Agreement).

Expected Outcome: For all areas:

1.More efficient access to the best research infrastructures available to researchers and innovators to conduct challenge-driven research, improve responsiveness to emerging challenges and foster innovation, irrespective of location, through a single-entry point access portal, integrated or interoperable catalogues of services and converging access conditions and selection procedures;

2.Breakthrough and leading-edge research enabled by advanced research infrastructure services, including joint research activities, made available to a wider user community, including in emerging areas of research;

3.A new generation of researchers trained to optimally exploit all the essential tools for their research with due attention to early-stage career researchers and researchers from widening countries and candidate countries;

4.Cross-disciplinary fertilisations and a wider sharing of information, knowledge and technologies across scientific fields fostered by closer interactions between researchers and innovators active in and around research infrastructures, through encouraging cross-disciplinary and interdisciplinary joint research activities for customised services and with due attention to research security; better management, including implementing FAIR data principle of the continuous flow of data collected or produced by research infrastructures.

Scope: For all areas:

This topic aims at providing trans-national access (on-site or remote) and/or virtual access to integrated and customised research infrastructure services for challenge-driven research and innovation in each of the areas listed below, offered by a wide range of complementary and interdisciplinary top level research infrastructures. Proposals should adhere to the guidelines and principles of the European Charter for Access to Research Infrastructures 80 .

Access also includes ad hoc users’ training and scientific and technical support (see Specific Features for Research Infrastructures). Additional training courses, including skills for data stewardship, may also be supported to prepare the new generations of researchers to properly exploit leading-edge research infrastructures. In addition, proposals should exploit the training potential of the successfully selected transnational access user projects by inviting researchers, notably early-stage career researchers, or research infrastructure technical staff from widening and candidate countries. Proposals should reserve sufficient resources for this purpose and should proactively advertise these opportunities (which should be arranged after the selection of user projects and have no impact on their evaluation).

The main goal of this topic is access provision to existing services: this should be clearly reflected by the proposed activities and the allocated resources. The improvement and development of services, relevant to the challenges, will also be supported, provided the resulting services are opened and offered already under the actions (short term R&D) and that the long-term sustainability of such services is ensured by the participant research infrastructures. Further development of new or improved services for use in the mid-term (2-3 years) may also be supported when duly justified e.g. to address well identified needs such as in the ESFRI Landscape Analysis, or in the research agendas of Horizon Europe Missions or Partnerships or for better serving the needs of open EU industrial research and innovation.

Data management (and related ethics issues), interoperability, as well as the connection of digital services (e.g. data services) to the European Open Science Cloud, should be addressed where relevant. Proposals should take due account of major European or international initiatives, of major EU priorities relevant in the domain. When appropriate, they should foster the use and deployment of (open) global standards.

Proposals should make available to researchers a wide, inclusive and comprehensive portfolio of complementary research infrastructure services of European interest 81 , including data services, and customised workflows to enable R&I addressing the set challenge. Proposals should include at least one ESFRI Landmark or European Research Infrastructure Consortium (ERIC) as beneficiary 82 . In case of a distributed ERIC, as an alternative to the ERIC participating as a beneficiary, a legal entity that is hosting ERIC facilities, resources or related services may participate as a beneficiary 83 .

Access could also be open, in accordance with the ‘Specific Features for Research Infrastructure’ section of this Work Programme, to third countries’ researchers. Research infrastructures from third countries may be involved when appropriate, including, if the proposal can demonstrate they offer complementary or more advanced services than those available in EU Member States and Associated Countries as beneficiaries or affiliated entities 84 .

Proposals should include an outreach and engagement plan to actively advertise their services, to targeted research communities, notably from widening countries and candidate countries, and to relevant industries, including SMEs and, if applicable, provide dedicated support for the development of research partnerships and collaborations with researchers from widening countries and candidate countries. Proposals are expected to exploit synergies and to ensure complementarity and coherence with other EU grants supporting access provision.

Proposals should include the list of services/installations 85 opened by research infrastructures for trans-national or virtual access and the amounts of units of access made available for users. Further conditions and requirements relating to access provisions that applicants should fulfil when drafting a proposal are given in the “Specific features for Research Infrastructures” section of this work programme part. Compliance with these provisions will be taken into account during evaluation.

The integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement. However, where applicable, proposals should mandate in their calls for access the integration of the gender dimension in the research and innovation content of the users applying to these calls.

Access opportunities should be presented in the single-entry point portal of the most appropriate pilot under HORIZON-INFRA-2027-01-SERV-01. The interoperability and capacity to converge into a common portal should be considered when designing or upgrading the portals as well as the possible connection to EOSC.

To ensure a holistic view from design to implementation of possible access schemes, proposals should ensure strong and continuous collaboration with the cross-domain preparatory action on access HORIZON-INFRA-2025-01-DEV-05 86 , with the pilots under topic HORIZON-INFRA-2026-01-DEV-02, e.g. making use of the catalogues of services, navigation tool and links to key EU initiatives, and with the actions supported under topic HORIZON-INFRA-2027-01-SERV-01. This collaboration should ensure a common front page to all above actions, set up by one of the pilots, highlighting the common objectives of EU supported access, the main conditions and requirements, providing preliminary guidance on access opportunities and directing to the single-entry point portal of each pilot. The collaboration should also promote, the implementation of simplified access pathways, good practices on call conditions, converging access modalities and selection process, as well as effective governance of the set of projects acting as an access programme with appropriate advisory bodies.

Proposals could consider the inclusion of the European Commission's Joint Research Centre (JRC) Nanobiotechnology Laboratory for Area 1 and Area 2 (see below) in their research infrastructure portfolio for its expertise at the interface between the research activities and regulatory aspects, and the European Laboratory for Structural Assessment for Area 4 (see below) for its expertise in testing full-scale structures for safety, and materials and structural components under very fast dynamic loads. In that respect, the JRC will consider collaborating with any successful proposal and this collaboration, when relevant, should be established after the proposal’s approval.

The topic targets the following areas related to scientific challenges and EU priorities. Proposals are expected to address one of the areas and must explicitly state which area they address:

Area 1: Advancing cancer research through integrated biomedical infrastructures

Actions should bring together several complementary and interdisciplinary key research infrastructures relevant for supporting the full cancer research lifecycle, facilitating the development of innovative treatments, including immunotherapies and personalized medicine. Services should include advanced imaging, genomics, and proteomics platforms, as well as clinical trials management, addressing cancer heterogeneity and epigenetics. Proposals should integrate and enable the reuse and sharing of data, samples, and services, and promote the use of artificial intelligence and digital technologies to analyse large datasets and develop predictive models of cancer biology and treatments.

Appropriate links and complementarities will be ensured with the HE Mission on cancer, EU4Health, and other key European and international initiatives, and when appropriate, build on results from past/ongoing projects, such as those funded under Horizon Europe topic HORIZON-INFRA-SERV-2021-01-01.

Area 2: Sustainable and resilient agrifood systems and agroecological transitions contributing to EU policies with a One Health approach and fostering EU competitiveness

Actions should bring together complementary key research infrastructures for enhancing R&I in sustainable agrifood systems and agroecological transitions, consistent with the One Health approach and supporting relevant EU policies and competitiveness. Proposals should encourage big data approaches by promoting trans-national access to similar or complementary genetic resources across several installations, adhering to FAIR principles, developing and applying AI and statistical applications and techniques. Links and complementarities with relevant initiatives should be established, such as with the EU Partnership on Agroecology and Agriculture of Data, the Mission Soil, where living-labs should promote agroecological practices and a holistic approach to sustainable and resilient agrifood systems. When appropriate, proposals should also build on results from past/ongoing projects such as the ones funded under Horizon Europe topic HORIZON-INFRA-SERV-2021-01-02 87 and avoid overlap with them.

Area 3: Resilient and sustainable polar ecosystems: understanding and managing climate, biodiversity, and human activity interactions

Proposals should provide access to a wide range of services, supporting R&I in polar regions and addressing key areas such as climate change impacts, biodiversity, ecosystem management, pollution, tourism, geo-political changes, and impacts on indigenous and local communities. The services should be adaptable, allowing for the integration of new technologies and methodologies, and should promote science diplomacy. They should, whenever relevant, involve indigenous and local communities into research activities, and consider traditional knowledge. Proposals should link with relevant European and international initiatives, such as the European Polar Board, the EU Polar Cluster, Copernicus, GEOSS, EMODNET, Antarctica InSync, the Greenland-EU partnership where relevant. Proposals should also build, if appropriate, on results from past/ongoing projects, such as those funded under Horizon Europe topic HORIZON-INFRA-2023-SERV-01-01 88 .

Area 4: Increasing material circularity and improving materials’ environmental performance

Actions should bring together several complementary and interdisciplinary key research infrastructures relevant for materials research and innovation for circularity and improved environmental performance of materials e.g. to achieve the goals of the Ecodesign for Sustainable Products Regulation and the Critical Raw Materials Act. The services should address different TRLs and they should be relevant for stakeholders along the whole value chain and in view of possible industrial applications. Services provided should help achieving the Green Deal’s ambitions for zero pollution and a toxic-free environment. When appropriate, proposals should also build on results from past/ongoing projects such as the ones funded under Horizon Europe topic HORIZON-INFRA-2021-SERV-01-04 89 and avoid overlap with them.

Area 5: Semiconductors: sustainable development of next-generation and future semiconductor chips and related technologies.

In line with the European Chips Act, actions should aim at providing research infrastructure service that contribute to R&I activities that help strengthening manufacturing activities in the Union, stimulating the European design ecosystem, and supporting scale-up and innovation across the whole semiconductor value chain. Proposals should ensure appropriate links, synergies and complementarities, also in terms of TRLs, with relevant activities in other parts of Horizon Europe and other initiatives at EU level in this field. When appropriate, proposals should also build on results from past/ongoing projects such as the ones funded under Horizon Europe topic HORIZON-INFRA-2023-SERV-01-01 90 and avoid overlap with them.

Area 6: Geosphere research infrastructures for advanced research on geohazards driven by the dynamics of the Earth and their dependency on human-induced changes.

Actions should bring together complementary and interdisciplinary geosphere research infrastructures that are key for understanding the dynamics of the Earth driving natural hazards (earthquakes, volcanic eruptions, landslides, tsunamis …) and their dependency on human-induced changes (such as climate and exploration, storage and exploitation of resources) and for strengthening science-policy-society interfaces, contributing to evidence-based decision-making.

HORIZON-INFRA-2027-SERV-01-03: Connecting research infrastructures and a wider user community across the European Research Area through access to advanced research infrastructure services

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants are not required to include in their proposal a plan for the exploitation and dissemination of the results as the main objective of these actions is the service provision.

The page limit of the application is 100 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply due to the specific nature of this topic:

1.Access provision activities must be included in the proposal. Please read carefully the provisions under the section “Specific features for Research Infrastructures” at the end of this work programme part before preparing your application.

Due to the scope of this topic, proposals must include at least two of the ESFRI Landmarks 91 or European Research Infrastructure Consortia (ERICs) 92 as beneficiaries. Such beneficiaries, and the research infrastructure(s) that they operate, must be explicitly identified in the proposal. For distributed ERIC the ERIC must be the beneficiary.

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The following additions to the general award criteria apply:

For the 'Excellence' criterion, in addition to its standard sub-criteria, the following aspects will also be taken into account:

The extent to which the access activities (trans-national and/or virtual access) will offer access to the state-of-the-art infrastructures of European interest in the field, high quality services, and will enable users to conduct excellent research.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries will be subject to the additional access rights:

The rules are described in General Annex G. The following exceptions apply:

Eligible costs may take form of unit costs for trans-national and virtual access to research infrastructures as defined in the Decision authorising the use of unit costs for the actions involving trans-national and virtual access (see Annex 2a of the Horizon Europe Model Grant Agreement).

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. Given the high operating costs of some state-of-the-art research infrastructures, the maximum amount to be granted to each third party is EUR 100 000, since the objectives of the action cannot be achieved otherwise. For the sake of efficiency, the FSTP calls can be combined with the calls for the access provision activities (see provisions under the section “Specific features for Research Infrastructures” of this work programme part).

Expected Outcome: Project results are expected to contribute to all the following expected outcomes:

1.Better connection of research infrastructures across the European Research Area reinforcing and spreading excellence throughout the European Research Area;

2.mitigating scattered national and regional research infrastructures and pockets of scientific excellence, and increasing the circulation of knowledge;

3.wider, simplified, and more efficient access to the best research infrastructures available to researchers to conduct curiosity-driven excellent research, irrespective of location;

4.breakthrough and leading-edge research enabled by advanced research infrastructure services made available to a wider user community;

5.enhanced integration of a wider user community in the European research infrastructure ecosystem; enhanced capacities of a wider user community to address research challenges and EU policy priorities; enhanced convergence of research capacities and increase of Europe’s competitiveness;

6.a new generation of researchers trained to optimally exploit all the essential tools for their research; better management, including implementing FAIR data principle, of the continuous flow of data collected or produced by research infrastructures.

Scope: The topic targets the further integration of a wider user community in the European RI ecosystem and the strengthening of this ecosystem across the entire European Research Area through access to research infrastructures and other activities. The proposed action should provide trans-national access (on-site or remote) and/or virtual access to services offered by a set of similar or complementary advanced national or pan-European research infrastructures, to enable curiosity-driven excellent interdisciplinary research. Proposals should adhere to the guidelines and principles of the European Charter for Access to Research Infrastructures[ https://op.europa.eu/publication-detail/-/publication/ec4692ae-ac6f-11ef-acb1-01aa75ed71a1 . Research infrastructures or laboratories from across the European Research Area should be consortium members and contribute to the offering of transnational access to services. Financial support to third parties may be used to extend the portfolio of services from access providers that are not beneficiaries, provided that the beneficiaries ensure that the conditions and requirements relating to access provisions as given in the “Specific features for Research Infrastructures” are fulfilled. Transnational access activities should be designed to stimulate excellence and impact and enhance convergence of research skills and capacities throughout Europe, with due attention to early-stage researchers.

Proposals should address all the following aspects:

1.Availability to researchers of a broad portfolio of research infrastructure services, including research infrastructures financed from funds under Union Cohesion Policy, which are relevant for frontier research in the chosen scientific area, including data services; all of the transnational access provisions should be led by the target of enhancing integration of a wider community in the European RI ecosystem;

2.Bi-directional exchanges within a wide user community of researchers/research groups across the European Research Area, including also networking activities, all of which potentially leading to longer term collaboration (including short-term exchange programmes, favouring direct interaction over online interaction);

3.Pro-active outreach measures to increase awareness about research infrastructure services among researchers in targeted countries; Activities targeting specifically early-stage researchers.

In the case of financial support to third parties (FSTP), the relevant conditions and requirements of the “Specific features for research infrastructures” of this work programme should be included in the FSTP calls and the applicants to the FSTP open calls, should be the third party research infrastructures demanded by user-group(s). In the case of transnational access, the beneficiaries select the user-groups according to the conditions and requirements of the “specific features for research infrastructures” section of this work programme, with the above mentioned further condition. The beneficiaries ensure that the access provider selected through the FSTP calls is a state-of-the-art research infrastructure, and that it will provide appropriate documentation to support and justify the amount of access provided and the information on the users as specified in the “specific features for research infrastructures” section of this work programme. To simplify the selection process, proposals under this topic may combine the calls inviting researchers to apply for transnational access and the FSTP calls so that a one stage selection procedure can be implemented based on a joint application from the user group submitting the ‘user project’ and the needed third party access provider. The recipient of the financial support is the third party research infrastructure that is providing access to the selected user-group(s). The financial support should cover the costs incurred by the third party to provide access (actual costs, unit costs, or a combination of the two) plus any work for service customisation as well as the travel and subsistence of users if visits are needed to use the infrastructures. Alternatively, proposals may opt for centrally managed travel and or subsistence costs for all or part of the selected user projects. In such case, these costs are excluded from the concerned FSTP.

Data management (and related ethics issues), interoperability, as well as the connection of digital services (e.g. data services) to the European Open Science Cloud, should be addressed where relevant. Proposals should consider major European or international initiatives relevant in the domain. Whenever appropriate, they should foster the use and deployment of (open) global standards. Proposals are expected to exploit synergies and to ensure complementarity and coherence with other EU grants supporting access provision. Proposals should include the list of services/installations 93 made available by the action for transnational or virtual access and the amounts of units of access made available for users. Further conditions and requirements relating to access provisions that applicants should fulfil when drafting a proposal are given in the “Specific features for Research Infrastructures” section of this work programme part. Compliance with these provisions will be taken into account during evaluation.

Proposals could consider the inclusion of the European Commission's Joint Research Centre (JRC) research infrastructures offering access to external users, that facilitates access and provides training and capacity building to users from user institutions in the European Research Area. In that respect, the JRC will consider collaborating with any successful proposal and this collaboration, when relevant, should be established after the proposal’s approval.

Destination INFRATECH - Next generation of scientific instrumentation, tools, methods, and advanced digital solutions of research infrastructures and fostering innovation and co-creation with industry (2026-27)

Research infrastructures require constant technology development to maintain and upgrade their services and to create new ones. The manufacturing capacity of industry is often required for this, and the co-creation of technological components is a defining feature of many research infrastructures.

The expected impact of the activities supported under this part of the destination notably includes:

1.Reinforced EU resilience with respect to the availability of critical technical research infrastructure components, considering that research infrastructure operations rely in many cases on technical components or material for which Europe is strongly dependent on third countries.

2.More robust research infrastructure innovation ecosystems, building also on activities funded in the past on the development of research infrastructure technology roadmaps and co-creation activities with industry.

3.Reinforced scientific, technological and industrial competitiveness through piloting of new modes of co-creation and co-innovation between research infrastructures and industry, including SMEs, startups and scaleups.

4.Accelerated digitalisation of research infrastructures throughout their entire life cycle, with due attention to research security.

5.Greening of research infrastructures, by advancing and accelerating the reduction of the environmental footprint of research infrastructures operations, while at the same time contributing to increasing their resilience towards energy crises or other resource restrictions such as water. Benefits of developments, notably digitalisation, should be balanced against possible costs for the environment.

Destination Earth (DestinE) is a Union flagship initiative developing a highly accurate, interactive digital model of the Earth to model, monitor and simulate natural phenomena, hazards and the related human activities. The DestinE system 94 provides an operational system to support decision-makers in designing accurate and actionable climate change adaptation strategies and mitigation measures and in addressing related complex societal problems and it is accessible for Horizon Europe projects.

The expected impact of the activities supported under this part of the destination notably includes:

1.Exploitation of the rapid advances in modelling, observations, digital technologies and ML/AI, including as foreseen in the AI Continent Action Plan 95 , ensuring that European leadership in this field is maintained;

2.Verification of modelling results by using observations of the research infrastructures in relevant fields;

3.Development, testing and validating digital twins and their cross-sectoral use by utilising Destination Earth system to cover unexplored areas/domains in addressing EU priorities and evolving end-user needs through multi-disciplinary solutions, pilots and demonstrators.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions and Innovation Actions falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Proposals are invited against the following topic(s):

HORIZON-INFRA-2026-TECH-01-01: R&D for the next generation of scientific instrumentation, tools, methods, digitalisation and solutions for research infrastructure upgrades

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 110.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The specific conditions for actions with PCP/PPI procurements in section H of the General Annexes apply to grants funded under this topic.

Expected Outcome: Project results are expected to contribute to several of the following expected outcomes:

1.enhanced scientific competitiveness of European research infrastructures;

2.enhanced research infrastructure capacity to address research challenges and EU policy priorities;

3.increased greening and resilience of research infrastructures;

4.increased efficiency of research infrastructures through digitalisation;

5.increased collaboration of research infrastructures with universities, research organisations and industry, fostering an innovation ecosystem that provides the foundations for the development of innovative companies and startups while considering EU technological sovereignty;

6.fostering the uptake of innovation outside the scientific research market, through co-development with industry of advanced technologies for research infrastructures;

7.integration of research infrastructures into local, regional, national and global innovation systems and promotion of entrepreneurial culture.

Scope: The aim of this topic is to deliver innovative scientific instrumentation, tools, digitalisation, methods and solutions which advance the state-of-art of research infrastructures (RIs) in the EU and Associated Countries and show transformative potential in RIs operation. The related developments, which underpin the provision of improved and advanced services, should lead RIs to support new areas of research and/or a wider community of users, including industrial users.

Cutting-edge technologies will also enhance the potential of RIs to contribute to addressing EU policy objectives and socio-economic challenges.

Proposals should be complementary with actions funded under topics HORIZON-INFRA-2022-TECH-01-01 96 and HORIZON-INFRA-2024-TECH-01-01 97 , targeting different instrumentation, tools, methods, digitalisation, and solutions. The complementarity with previous actions should be clearly explained in the proposal.

Proposals should address the following aspects, as relevant:

1.research and development of new scientific instrumentation, tools, digitalisation, and methods for research infrastructures;

2.their technology validation and prototyping;

3.training of RI staff for the operation and use of these new solutions; when relevant, developing skills on technical validation to industrial standards;

4.the innovative potential for industrial exploitation of the solutions and/or for the benefits of the society, including technology concept or validation in laboratory for use by SMEs startups or scaleups.

To minimise the research infrastructures’ environmental footprint and increase resilience e.g. with respect to energy consumption, climate-related aspects or use of critical components and materials, greening and resilience aspects should be addressed for all proposed scientific instrumentation, tools, methods, digitalisation, and solutions.

Developments for the specific use case of research infrastructures are expected to go beyond TRL 4. When proposed developments have the potential to lead to applications beyond the specific use case of research infrastructures, the TRL of these additional developments should go up to TRL 3-4.

Proposals should include at least two different research infrastructures as beneficiaries 98 each of them being an ESFRI research infrastructure 99 a European Research Infrastructure Consortium 100 (ERIC) or another research infrastructure that is an international European research organisation 101 .

Other technological partners, including industry, SMEs, startups or scaleups should also be involved, thus promoting innovation and knowledge sharing through co-development of new technical solutions for research infrastructures with due consideration of EU technological sovereignty.

Proposals may include PCP 102 subcontracting activities as described in part H of the General Annexes of the work programme. This option encourages the use of public procurements for the competitive development of new specific solutions, whilst opening market opportunities for industry and researchers active in the EU and Associated Countries. By establishing the procurement process in consecutive phases, the PCP activity can support the development of competing designs, prototypes, and solution testing. This ensures that investment risks do not prevent tackling specific scientific and technological issues and allows a problem to be approached from different angles and to test different solutions.

Proposals are encouraged to incorporate in the development and deployment of innovation, where applicable, principles in line with the EU’s environmental policies such as Safe and Sustainable-by-Design (SSbD), circular-by-design and others.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement. However, where applicable in the proposed developments, proposals should consider the integration of the gender dimension in the research and innovation content.

HORIZON-INFRA-2026-TECH-01-02: Digital twins and/or their major components for environment, climate and security

Call: Research Infrastructures 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 7.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 15.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Beneficiaries must make use of the European Commission’s Destination Earth system 103 .

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 7 or higher by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 104 .

Expected Outcome:

1.Improved security and preparedness for the Union and more disaster resilient society facing the adverse effects of climate change;

2.Improved capacity of key users and decision-makers to anticipate, mitigate and contain risks at the vulnerable societal sectors at the intersection of climate change, environment and security;

3.Further development of the data lab infrastructure around Destination Earth in line with the AI continent Action Plan 105  

Scope: Climate change has both direct and indirect consequences to the security of our societies. To be able to address the intricate connections between climate change and security to various impact sectors, Europe needs to be equipped with adequate tools, technologies and methods that enable addressing these complex issues and exploit the recent advances in AI, high-performance computing and other new digital technologies.

Digital twins for civil security require the development of high-accuracy and fast-response models at local and regional levels to strengthen preparedness and resilience, protect EU citizens and raise risk awareness both inside and outside the EU. The topic focuses on new digital twins, or major new components of existing digital twins, to strengthen foresight and anticipation capabilities at the intersection of environment, climate and security. In addition to climate and environmental issues, possible security related impact sectors include, but are not limited to, natural or human-induced disasters, health and related emergencies, energy sustainability and management, migration, or resource scarcity (e.g. food and water). The proposed cross-disciplinary solutions should cover risk mitigation, prevention and foresight, and make use of the Destination Earth system capabilities. The focus is on local and/or regional models, primarily in Europe and its neighbourhood. If necessary, some indicators can also be provided at regional / global levels.

The work should benefit from rapid advances in modelling, observations and data fusions, artificial intelligence and machine learning, state-of-the art processing and visualisation capabilities, and enable workflows to support users in key impact sectors.

The proposals should cover the following aspects:

1.Development of new digital twins, or major new components of existing digital twins, to strengthen foresight and anticipation capabilities at the intersection of environment, climate and security in short (operational), medium (tactical) and long-term (strategical) scenarios;

2.Demonstrated usability through Minimum Viable Products (MVP) in at least three application areas linking to climate, environment and security, with the involvement of real users;

3.Advancing the state-of-the-art in modelling, observations and data fusions, artificial intelligence and machine learning, processing, advanced visualisation capabilities and detection features, and workflows to support users in key impact sectors;

4.High computational capacity to implement responsive visualization interfaces that allow advanced visualization capabilities (e.g. 3D, virtual reality, interactive simulations) for decision-makers;

5.Coherent integration between satellite and other data (e.g. statistics, in situ, UAV Earth Observation data), and at least two sources in a modular architecture that guarantee the progressive injection of the additional data sources, including high quality observational and other data from the research infrastructures. In case of sensitive datasets, a coherent and comprehensive plan is needed, explaining how the data access will be granted to develop the proposed models and services and how these data will be progressively integrated;

6.Clear pathway towards integration with the Destination Earth system, and further development of the data lab infrastructure around Destination Earth for new AI-enabled digital twins using the Data Labs of the AI Factories and integrating them in the DestinE system;

7.Enable informed decision-making by non-technical experts and policy makers through assistance of (generative) AI models enabling user requirements analysis and narrowing down vast amounts of data and information into actionable and understandable scenarios;

8.Clear pathway towards integration with the Destination Earth system regarding the infrastructure architecture, data and services, and identifying which capacities - depending on the scenario - can be directly used in Destination Earth, and which ones would need to be adapted to deal with sensitive issues;

9.Demonstrated trustworthiness in the ethical use of AI;

10.Robustness and accuracy of the models to be reliable for security usage.

The proposals should demonstrate clearly and with measurable indicators how they contribute to key Union priorities on adapting and preparing for a changing climate, crisis preparedness and disaster resilient society. They should leverage on the relevant parts of the EU’s AI Continent Action Plan.

The proposals should demonstrate a clear and credible pathway towards collaboration with the implementing entities of Destination Earth initiative (European Space Agency (ESA), European Centre for Medium-Range Weather Forecasts (ECMWF) and European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT)).

Proposals will need to adhere to the standards and best practices set by the Destination Earth initiative of the European Commission to allow coupling with the existing Destination Earth system. The proposed work is expected to ensure synergies with major European digital twin developments related to security (in particular those of the European Union Satellite Centre 106 (SatCen)), and other digital twin developments relevant to the chosen application fields. They should also leverage the knowledge and solutions generated in the relevant Horizon Europe projects, in particular those selected from HORIZON-INFRA-2021-TECH-01, HORIZON-INFRA-2024-TECH-01 and HORIZON-INFRA-2025-TECH-01). Synergies with the Common European Data Spaces 107 and in particular with the European Open Science Cloud (EOSC) are also encouraged.

Proposals should also aim to address the possible use of the project outcomes in existing or new service offers by the Member States, Associated Countries or the European Union, like the relevant Copernicus services.

HORIZON-INFRA-2027-TECH-01-01: Testing and optimising models of co-creation of advanced research infrastructure technologies

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 10.00 and 15.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 30.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply: due to the specific nature of this topic, consortia must include at least two different research infrastructures as beneficiaries, each of them being an ESFRI infrastructure 108 , and/or a European Research Infrastructure Consortium (ERIC) 109 or another research infrastructure that is an international European research organisation 110 . Such beneficiaries, and the research infrastructure(s) that they operate, must be explicitly identified in the proposals 111 .

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries may provide financial support to third parties (FSTP). The support to third parties can only be provided in the form of grants.

The maximum amount to be granted to each third party is EUR 500,000. This amount is justified since the projects funded will support the creation of an innovation ecosystem through concrete collaborative R&I projects, and research infrastructures will be engaged in different technological collaborations. Due to the nature of this action, a threshold lower than EUR 500,000 would hinder the engagement of research infrastructures with different partners; this would not allow for the creation of an ecosystem supporting the take up of technological innovations resulting from the use of research infrastructures.

The specific conditions for actions with PCP/PPI procurements in section H of the General Annexes apply to grants funded under this topic.

Expected Outcome: The objective of this topic is strengthening the European research infrastructure landscape as a pillar of Europe’s innovation-based competitiveness and reinforcing its role in the overarching policy priority of making Europe the top region for deep-tech startups and scaleups. Project results are expected to contribute to several of the following expected outcomes:

1.Enhanced scientific and technological competitiveness of European research infrastructures, through the co-development of innovative technologies and solutions that improve the performance of RI services, addressing common needs across different types of research infrastructures, where applicable.

2.Increased cooperation and coordination between European research infrastructures, and between them and other public and private research performing organisations, in order to create a coherent and supportive ecosystem for deep-tech innovation in Europe.

3.A strengthened role of research infrastructures as centres of gravity for deep-tech innovation ecosystems.

4.Strengthened EU innovation capacity and technological sovereignty.

Scope: The topic focuses on supporting research infrastructures in developing and implementing innovative technologies and solutions improving the performance of their scientific services, while fostering cooperation with other research organisations, industry, and start-ups and scaleups to maximise the spillover effects of new RI technologies. Proposals should address all of the following aspects:

1.Co-creation of advanced technologies that address research infrastructures needs, considering resource efficiency and environmental impacts as well as technological sovereignty.

2.Development of partnerships and collaborations between research infrastructures and different types of research performing organisations including industry, to co-create technological solutions and promote their uptake and exploitation outside of the science market.

3.Shared understanding of the commercial potential of innovative technologies, and support from RI technology transfer teams as early as necessary.

Developments for the specific use case of research infrastructures are expected to go beyond TRL 4. When proposed developments have the potential to lead to applications beyond the specific use case of research infrastructures, the TRL of these additional developments should go up to TRL 3-4. Proposers should clearly describe which TRL will be reached at the end of the project for each proposed development.

Projects are expected to share experiences about co-creation models with the project funded under HORIZON-INFRA-2025-01-DEV-05, area 3.

Proposals may include PCP 112 subcontracting activities as described in part H of the General Annexes of the work programme. This option encourages the use of public procurements for the competitive development of new specific solutions, whilst opening market opportunities for industry and researchers active in the EU and Associated Countries. By establishing the procurement process in consecutive phases, the PCP activity can support the development of competing designs, prototypes, and solution testing. This ensures that investment risks do not prevent tackling specific scientific and technological issues and allows a problem to be approached from different angles and to test different solutions.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement.

HORIZON-INFRA-2027-TECH-01-02: Pioneering Destination Earth for a Sustainable Future: Large-Scale Pilots and Demonstrators

Call: Research Infrastructures 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 7.00 and 12.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 30.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Beneficiaries must make use of the European Commission’s Destination Earth system 113 .

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 5 or higher by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 114 .

Expected Outcome:

1.Actionable and widely tested research-to-action pilot solutions in addressing complex cross-sectoral problems caused and/or exacerbated by climate change in key socio-environmental and socio-economic sectors.

2.Innovative use of Artificial Intelligence (AI) by further development of the data lab infrastructure around Destination Earth in line with the AI continent Action Plan 115 .

3.Multi-country approach with real end user engagement to ensure solutions that are accessible, and effectively integrated into real policy, preparedness and response efforts.

Scope: The focus is on large-scale pilots and demonstrators to enable researchers, expert and non-expert users, including decision-makers, to experiment with and through the existing Destination Earth system and harness it to widespread cross-societal use through new innovative methods, practices, tools and services. It will also leverage on the recent AI Continent Action Plan and the further development of the data lab infrastructure by bringing together and federating data from different AI Factories, linking to the corresponding Common European Data Spaces and making this data available to AI developers and ensuring their access to large volumes of high-quality data.

The proposals should cover all following aspects:

1.Planning, designing, and overseeing large-scale experimental pilots and demonstrators by using Destination Earth capabilities in critical impact sectors linked to public policy areas, tackling real-world challenges in relation to climate change adaptation and risk mitigation, and foster solutions that address clearly specified needs at European, national, regional and local scale.

2.The pilots and demonstrators should improve the models and enable the coupling of models used in different sectors to combine cross-sectoral research and practice. They should consider the complex interrelationships emerging from the challenges caused and/or exacerbated by climate change, like for example climate-induced health effects or changes in the energy, agri-food or mobility sectors, and propose, test and analyse adaptation and risk mitigation measures in real-life scenarios to be able to respond effectively to these complex challenges in the future.

3.The pilots should contribute to the data infrastructure around Destination Earth for new AI-enabled digital twins by using the Data Labs of the AI Factories and integrating them in the DestinE system. Involvement of SMEs and/or startups, active in AI and/or deep tech and working in close collaboration with scientific research community is strongly encouraged.

4.The pilots and demonstrators should be co-designed and experimented in at least three Member States and/or Associated Countries in close collaboration between research scientists, AI developers, public sector policy experts and decision-makers.

5.The solutions need to demonstrate sustainable set-ups, including through interactivity with digital twins, adapting to changing data and on-demand visualisation capabilities and answering to existing and emerging socio-environmental and socio-economic challenges and the use of AI in solving them.

The pilots and demonstrators should fully integrate place-based governance, socio-economic and identity characteristics and other context-specific data to ensure tailored, effective, and actionable responses. They should enable authorities to implement targeted, data-driven measures that enhance resilience, preparedness, and decision-making in their respective territorial contexts.

Proposals will need to adhere to the standards and best practices set by the Destination Earth initiative to enable interoperability with the Destination Earth system. To the extent possible, the Destination Earth platform should be used as to facilitate the deployment and scalability of the proposed solutions, while enhancing their accessibility and impact across multiple sectors and user communities across Europe.

To maximize impact, the work plan should include a scalability plan that drives the widespread adoption of the innovative use and solutions powered by Destination Earth, latest technologies, and scientific developments. It should be developed in close collaboration with the relevant public authorities and outline a clear, actionable pathway aiming to secure long-term commitments, including funding, governance and policy framework to ensure lasting impact beyond the projects’ duration.

The proposals should demonstrate a clear and credible pathway towards collaboration with the implementing entities of Destination Earth initiative (European Space Agency (ESA), European Centre for Medium-Range Weather Forecasts (ECMWF) and European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT)), and other key initiatives active in the intended impact sectors, like Mercator Ocean International, leading the European Digital Twin Ocean initiative.

The proposals should also leverage the knowledge and solutions generated in the relevant Horizon Europe projects, in particular those selected from HORIZON-INFRA-2021-TECH-01, HORIZON-INFRA-2024-TECH-01 and HORIZON-INFRA-2025-TECH-01. Strong links with the aims, actors and projects serving the Horizon Europe missions, in particular the Climate Adaptation Mission, are encouraged. Synergies with the Common European Data Spaces 116 and in particular with the European Open Science Cloud (EOSC) are also encouraged.

Proposals should also aim to address the possible use of the project outcomes in existing or new service offers by the Member States, Associated Countries or the European Union, like the relevant Copernicus services.

Destination INFRANET – Network connectivity in research and education - enabling collaboration without boundaries

In today’s world, ultra-fast hyperconnected networks, robust security, trust and identity solutions, and integrated above-the-net services reshape the context in which scientific and educational activities are conducted. High-performance computing (HPC), cloud-based environments, AI-driven solutions and other new and emerging technologies are key enablers of scientific progress. These technologies offer unprecedented potential to accelerate discovery and innovation, yet they also introduce new challenges in data accessibility and findability, advanced trust and identity frameworks, and resilient high-capacity connectivity. Looking ahead, the ability to adapt to disruptive technologies, integrate quantum-secure architectures, and expand AI-driven services will be critical to maintaining high standards of reliability and trust in Europe’s digital research environment.

National Research and Education Networks (NRENs) should address these evolving demands by delivering on high-speed connectivity, solid trust frameworks, and scalable digital services for advanced scientific collaboration. Through GÉANT (Gigabit European Academic Network), the NRENs will continuously improve their infrastructure, broaden innovative services, and address emerging challenges, enabling Europe’s knowledge communities to exchange resources swiftly, securely and on a global scale, and reinforcing Europe’s position as a competitive, resilient, and forward-looking digitally empowered research and innovation ecosystem.

The target of the Destination under this work programme is to carry on building upon the Framework Partnership Agreement's expected outcomes, delivering state of the art network connectivity, above-the-net innovative services and operational excellence for the NRENs.

This Specific Grant Agreement (SGA) under the current Framework Partnership Agreement (FPA) will build upon and complement the foundations and achievements of the previous SGAs. It ensures both continuity with the past activities and alignment with new emerging priorities in digital resilience and security, strategic autonomy, and technological competitiveness. It will seamlessly bridge the activities towards the next Multiannual Financial Framework (MFF) in enhancing the scalability, sustainability and adaptability, and will endow NRENs with the necessary capabilities to deliver state-of-the-art solutions to European research and education community.

The Specific Grant Agreements (SGAs) implementing the FPA action plan are included under "Other actions". Therefore, there is no call for topics under this Destination.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions and Innovation Actions falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Other Actions not subject to calls for proposals

Grants to Identified Beneficiaries

1. Sustaining the EOSC monitoring mechanism

Expected outcome: Project results are expected to contribute to all the following outcomes:

1.Operation, maintenance and development of a policy intelligence tool for monitoring policies, investments, digital research outputs, skills and infrastructure capacities related to Open Science and the European Open Science Cloud (EOSC);

2.Investigation, preparation and handover of the developed tool to a willing EOSC-related entity based on the developed sustainability plans during the EOSC Track project, potentially subject to approval by the responsible governance (e.g. EOSC Tripartite or EOSC Federation governance);

3.Coordination and alignment with and contribution to the monitoring of the EOSC Federation and the monitoring of the EOSC Partnership;

4.Support to the alignment of surveys and monitoring initiatives related to Open Science in Europe.

Expected impact:

1.Continued support to the EOSC Tripartite governance as a monitoring data aggregator to cover trends in Open Science policies, practices, and impact across Europe and fulfil Open Science monitoring requirements arising from the European Research Area (ERA) Policy Agenda.

2.Long-term sustainability of the policy intelligence tool based on the developed sustainability plan, e.g. by (partial) integration into the governance and financing structure of the EOSC Federation.

Scope:

The ERA Policy Agenda 2022-2024 includes the action to enable the open sharing of knowledge and the re-use of research outputs, including through the development of the EOSC. A corresponding action is included in the Commission proposal for the ERA Policy Agenda 2025-2027, by enabling open science via sharing and re-use of data, including through the EOSC.

To continuously assess progress on this action, a monitoring mechanism is required to collect data and benchmark policies, investments, digital research outputs, skills and infrastructure capacities related to the EOSC. This monitoring mechanism shall provide the Commission, the Member States and Associated Countries and the EOSC European Partnership with the baselines, trends, and best practices along the three levels of EOSC implementation (European, national, and institutional). It shall provide FAIR monitoring data allowing the EOSC governance to pursue statistical analyses on-demand to assess the impact of EOSC related policies and investments

A first version of a policy intelligence tool was implemented in 2023 in the context of the ‘EOSC Future’ project, to help assessing EOSC implementation at various levels and to contribute to the monitoring of the uptake of Open Science in Europe.

In the context of the ‘EOSC Track’ project from 2024 to 2026, OpenAIRE AMKE continues to operate, maintain and further develop the policy intelligence tool for monitoring policies, investments, digital research outputs, skills and infrastructure capacities related to EOSC, and to ensure the necessary links to the new ERA monitoring mechanism. This particularly includes a relaunch of the corresponding platform “EOSC Open Science Observatory” to collect, analyse and visualise data on the implementation and uptake of open science across Europe. For this purpose, the platform also collects data automatically from trusted data sources, leveraging on the OpenAIRE established resources and through continuous surveys to the EOSC stakeholders.

The platform should moreover calculate and make available specific indicators to monitor the open sharing of knowledge and the re-use of research outputs across the ERA and beyond, and the EOSC readiness of Member States and Associated Countries and their actions and investments (financial and in-kind contributions) contributing to the EOSC Partnership and the EOSC implementation, for the first time reflecting on trends and impact of Open Science principles. The EOSC Track project in addition shall create a sustainability plan for operating and maintaining the tool beyond the project duration.

The identified beneficiary will:

1.continue to operate and maintain the policy intelligence tool for monitoring policies, investments, digital research outputs, skills and infrastructure capacities related to EOSC, and ensure the necessary links to the new ERA monitoring mechanism;

2.align with and contribute to the uptake of the monitoring of the EOSC Federation and the monitoring of the EOSC Partnership. This might include mild developments in the existing policy intelligence tool during the project duration.

3.on the basis of the sustainability plan developed throughout the EOSC Track project, investigate, prepare and execute the handover of the policy intelligence tool to a willing EOSC-related entity. A corresponding handover might be subject to approval by the EOSC Tripartite governance or EOSC Federation governance to ensure continuous operations.

The Commission considers that a duration of 2 years for this action would be appropriate. If necessary to implement the action, the beneficiary may award subcontracts covering the implementation of certain action tasks that will be described in the proposal.

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation.

In addition, OpenAIRE AMKE is uniquely positioned to provide European wide information on research and scholarly digital outputs and to run and analyse surveys on the subject of Open Science. OpenAIRE is a participatory infrastructure via its established network of 34 National Open Access Desks (NOADs) in the Member States and Associated Countries. It harvests information of open scholarly results and data and provides services for discoverability, accessibility, and monitoring of data-driven research results. The OpenAIRE AMKΕ legal entity is established as a non-profit partnership to ensure a permanent presence and structure for a European-wide policy and open scholarly communication infrastructure.

Specific conditions: Procedure: The evaluation committee will be fully composed by representatives of EU institutions.

Legal entities:

OpenAIRE AMKE, 6 Artemidos Str & Epidavrou, 15125 Marousi – Greece

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Second quarter 2026

Indicative budget: EUR 0.40 million from the 2026 budget

2. Coordination and Monitoring of the European Research Infrastructure Consortia (ERICs)

Expected Outcome: Project results are expected to contribute to all the following outcomes:

1. European and national authorities, funding agencies, ESFRI, research infrastructures, and other ERA stakeholders have access to updated and consolidated data and information on ERICs;

2. The impact and visibility of the ERICs and the role of the ERIC Forum are enhanced; compliance with the ERIC Regulation can be further assessed and strengthened; assessment of the implementation of the ERIC Regulation is facilitated;

3. Evidence for future strategic development of the ERICs, best practices, a common approach for monitoring such as that developed by ESFRI, identification of key performance indicators including indicators on impact.

Expected Impact: Proposals should set out a credible pathway to contribute to several of the expected impacts of Destination INFRADEV.

Scope: The European Research Infrastructure Consortium (ERIC) 117 legal framework facilitated the establishment and operation of more than thirty pan-European research infrastructures 118 , enhanced trust among funding countries to jointly invest in these infrastructures and contributed to integrating and structuring the research infrastructure landscape.

The Regulation requires each ERIC to produce an annual report covering the scientific, operational and financial aspects of its activities. However, the level of details of these reports is not defined. The ERIC Forum, set up to ensure coordination and secretariat support for the ERICs, has successfully delivered in its objectives and corresponds to a well-needed support activity.

In this context, the proposal should address, inter alia, all following aspects:

Monitoring and reporting

1. Further collecting and maintaining basic data and information on the ERICs (such as ERIC statutes, memberships, annual reports, links to Commission Decisions, to ERICs websites);

2. Further development, maintenance and optimisation of the online platform developed by the ERIC Forum 2 project reflecting data and knowledge on the ERICs, compliant with FAIR principles with appropriate management of access rights. The platform should notably enable easy upload and update of relevant data and information by the ERICs or their members. The platform should provide effective and tailored access to data and information to the Commission, ESFRI and ERIC stakeholders and the general public;

3. Continued collection of detailed data and information beyond basic information, taking into account the work of the assessment of the Commission expert group on the implementation of the ERIC Regulation 119 , the Commission report on the application of the ERIC Regulation 120 , the EU priorities including the renewed ERA and appropriate consultation of stakeholders such as the ESFRI Stakeholder Forum; including the use of key performance indicators, which may be tailored to each ERIC, to track issues such as industrial collaboration;

Analysis in support of research infrastructure policy

1. Ensuring in particular synergies and compatibility with the activities and outcomes of the ERA Policy Agenda 2025-2027 on strengthening sustainability, accessibility and resilience of research infrastructures in the European Research Area;

2. Assessing and reporting on the needs and progress of ERICs towards the green and digital transition;

3. Reporting on consistency and complementarity of ERIC developments with ESFRI as relevant;

4. Providing guidance and recommendations to ERICs as a whole on issues such as sustainability and access models, internationalisation, industrial collaboration, and employment models.

Secretariat and back-office services

1. Supporting the network of ERICs (‘ERIC Forum’), including a secretariat, in strengthening the structured cooperation between ERICs, the external representation of the ERICs as relevant stakeholders in consultations and other policy actions that could affect them, and by identifying and promoting best practices including for the support of ERICs in preparation;

2. Implementation of potential shared administrative back-office services among the ERICs, such as standard protocols, templates, reporting, HR, IT, communication or other services, to streamline coordination, optimise resources and support the ERICs in preparation.

The proposal should ensure close coordination with the Commission including liaising with ESFRI and relevant stakeholders. It should build strongly on the expertise of the individual ERICs as well as on the experience gained as a network in the context of the ERIC Forum.

This grant will be awarded without a call for proposals according to Article 195(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation as, due to the scope of this action, the potential beneficiaries are uniquely identified as the existing ERICs set up on the basis of the Council Regulation (EC) No 723/2009. They are free to organise themselves as regards which of them will be beneficiaries to achieve the necessary objectives of this action.

Specific conditions

Legal and financial set-up of the Grant Agreements: The rules are described in General Annex G. The following exceptions apply:

1. Beneficiaries will be subject to the additional access rights: beneficiaries shall grant royalty-free access to their intellectual property relating to tools, standards, specifications, and other relevant outputs generated by this action to the EU institutions and to the beneficiaries of related projects funded by the EU. This access shall be provided through a well-defined mechanism, during and beyond the lifespan of the Grant Agreement for the continuity of the coordination and monitoring of the implementation of the ERIC legal framework.

2. Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 121 .

Procedure: The evaluation committee will be fully composed by representatives of EU institutions.

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes.

Legal entities:

ACTRIS ERIC, Erik Palmenin Aukio 1, 00560, Helsinki, Finland

Analysis and Experimentation on Ecosystem ERIC (AnaEE-ERIC), 1 Avenue de la Terrasse, 91190, Gif Sur Yvette, France

Biobanks and Biomolecular Resources Research Infrastructure Consortium (BBMRI-ERIC), Neue Stiftingtalstrasse 2/B/6, 8010, Graz, Austria

Central European Research Infrastructure Consortium ERIC (CERIC-ERIC), SS. 14, km 163.5 in Area Science Park, 34149, Trieste, Italy

CESSDA ERIC, Parkveien 20, 5007, Bergen, Norway

CLARIN ERIC, Drift 10, 3512 BS, Utrecht, Netherlands

Cherenkov Telescope Array Observatory ERIC (CTAO ERIC), Via Piero Gobetti 93/3 40129 Bologna, Italy

International Centre for Advanced Studies on River-Sea Systems European Research Infrastructure Consortium (DANUBIUS-ERIC), Murighiol, Tulcea County, Romania

Digital Research Infrastructure for the Arts and Humanities (DARIAH ERIC), Avenue de France 190-198, 75013, Paris, France

EATRIS ERIC, De Boelelaan 1118, 1081 HZ, Amsterdam, Netherlands

ECCSEL European Research Infrastructure Consortium (ECCSEL ERIC), Kolbjorn Hejes Vei 1A, 7491, Trondheim, Norway

ECRIN European Clinical Research Infrastructure Network (ECRIN-ERIC), 5 Rue Watt, 75013, Paris, France

European Holocaust Research Infrastructure (EHRI-ERIC)

European Research Infrastructure for Heritage Science (E-RIHS ERIC)

Extreme Light Infrastructure ERIC (ELI ERIC), Za Radnici 835, 252 41, Dolni Brezany, Czechia

European Marine Biological Resource Centre European Research Infrastructure Consortium (EMBRC-ERIC), 4 Place Jussieu, 75005, Paris, France

European Multidisciplinary Seafloor and Water Column Observatory - European Research Infrastructure Consortium (EMSO ERIC), Via di Vigna Murata 605, 00143, Roma, Italy 

European Plate Observing System — European Research Infrastructure Consortium (EPOS ERIC)

European Social Survey European Research Infrastructure Consortium, ESS ERIC, Headquarters City, University of London, Northampton Square, EC1V 0HB, London, United Kingdom

European Infrastructure of Open Screening Platforms for Chemical Biology European Research Infrastructure Consortium (EU-OPENSCREEN ERIC), Robert-Rossle-Str. 10, 13125, Berlin, Germany

EURO-ARGO ERIC, Zi de la Pointe du Diable Technopole Brest Iroise, 29280, Plouzane, France

EURO-BIOIMAGING ERIC, PL 123, 20521, Turku, Finland

European Spallation Source ERIC , Odarslovsvagen 113, 224 84, Lund, Sweden

European Solar Research Infrastructure for Concentrated Solar Power (EU-SOLARIS ERIC), Carretera A Senes Km 4, 04200, Tabernas, Spain

Integrated Carbon Observation System European Research Infrastructure Consortium (ICOS ERIC), Erik Palmenin Aukio 1, 00560, Helsinki, Finland

INFRAFRONTIER ERIC, Ingolstaedter Landstrasse 1, 85764, Neuherberg, Germany

INSTRUCT-ERIC, Oxford House, Parkway Court, John Smith Drive, OX4 2JY, Oxford, United Kingdom

Joint Institute for Very Long Baseline Interferometry as a European Research Infrastructure Consortium (JIV-ERIC), Oude Hoogeveensedijk 4, 7991 PD, Dwingeloo, Netherlands

E-SCIENCE European Infrastructure for Biodiversity and Ecosystem Research (LifeWatch ERIC), Plaza de Espana S/N, Sector II-III, 41071, Sevilla, Spain

Low Frequency Array European Research Infrastructure Consortium (LOFAR ERIC), Oude Hoogeveensedijk 4, 7991 Pd, Dwingeloo, Netherlands

Microbial Resource Research Infrastructure - European Research Infrastructure Consortium (MIRRI-ERIC), Universidade Do Minho Campus De Gualtar Cp 3 Piso, 4710-057, Braga, Portugal

European Research Infrastructure Consortium for the Survey of Health, Ageing and Retirement in Europe (SHARE-ERIC), Amalienstrasse 33, 80799, München, Germany

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Fourth quarter 2027

Indicative budget: EUR 3.50 million from the 2027 budget

3. Reinforcing the coordination and support to the EOSC Federation

Expected outcome: Project results are expected to contribute to all the following outcomes:

1.continued support towards the implementation and further development of the European Open Science Cloud (EOSC) Federation of existing and new EOSC Nodes;

2.continued coordination between the EOSC Nodes, the EOSC Association and the overall EOSC Federation governance, for what concerns the implementation and further development of the EOSC Federation;

3.continued implementation of communication activities and community-engagement activities in relation to the EOSC Federation;

Expected impact:

1.ensuring adequate support and coordination of an enlarging EOSC Federation and effective interactions within its organisational structure.

2.ensuring effective concertation of complementary support provided by related INFRAEOSC projects and securing continuation of coordination and support activities beyond their end.

Scope:

The launch of the EOSC EU Node in 2024 and the inclusion of additional candidate EOSC Nodes as of 2025 kick-started the building of the EOSC Federation as an interconnected, distributed system of existing research and data infrastructures and scientific service provides across Europe.

The EOSC Federation is being developed and implemented through the communities’ own contributions and the EU’s contribution through Horizon Europe, on the basis of the common understanding under the EOSC co-programmed Partnership. The own contributions of the communities participating in the EOSC Federation have been instrumental for ensuring their readiness and capacity to serve EOSC users and for adopting Federation-wide standards and policies. At the same time, since the beginning of the building of the EOSC Federation there was a clear need for adequate coordination and support activities to ensure the efficient interaction among the EOSC Nodes, and the coordination of their activities towards achieving the Federation’s objectives. To this end, the EOSC Tripartite Governance, a forum that provide the overall strategic steering of EOSC and where the European Commission, the EOSC Steering Board consisting Members from the EU Member States and countries associated to Horizon Europe and the EOSC Association are represented, endorsed the implementation of such coordination and support activities during the building of the EOSC Federation by the EOSC Association, in concertation with related INFRAEOSC projects, in particular EOSC United and EOSC Gravity 122

As the EOSC Federation enlarges and increases its reach to multiple communities and users, so will the needs for adequate coordination and support activities. Moreover, as the duration of the co-programmed EOSC Partnership approaches its end, it is crucial to ensure the sustained implementation and smooth transition of the EOSC Federation towards any potential decision about its future after 2027.

The aim of the funded project should be to reinforce the support and coordination activities of the EOSC Federation and to ensure their sustained implementation beyond the duration of relevant INFRAEOSC projects. In the context of this project, the identified beneficiary will:

1.continue and reinforce its contribution to the coordination, support, communication and community-engagement activities for the development and implementation of the EOSC Federation (including but not limited to providing secretarial support and collaboration tools to different groups and task forces, organising workshops, meetings and webinars, communication and awareness raising campaigns) ensuring complementarity with activities by relevant EOSC projects, in particular EOSC United 123 and EOSC Gravity 124 , and ensure the smooth continuation of relevant activities beyond the end of the projects;

2.continue and reinforce its support to the effective interaction between the different organisational bodies, including those charged with the overall strategic decision-making, the implementation and the coordination and support of the EOSC Federation.

The Commission considers that a duration of 2 years for this action would be appropriate. If necessary to implement the action, the beneficiary may award subcontracts covering the implementation of certain action tasks that will be described in the proposal.

This grant will be awarded without a call for proposals according to Article198(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation.

Given its current role in the context of the development and implementation of the EOSC Federation and in related INFRAEOSC projects, the EOSC Association AISBL is uniquely positioned to ensure optimal implementation of the outlined activities for the above duration. The EOSC Association AISBL is an international non-profit organization established to represent the research community in the coordination and implementation of EOSC and the Commission’s partner under the EOSC co-programmed Partnership.

Specific conditions: Procedure: The evaluation committee will be fully composed by representatives of EU institutions.

Legal entities:

EOSC Association

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Second quarter 2027

Indicative budget: EUR 0.60 million from the 2027 budget

4. Strengthening the international dimension of ESFRI and/or ERIC research infrastructures – consolidating the SESAME facility

Expected outcomes:

1.Higher-quality user support with enhanced and more diverse services using the existing and near-term future SESAME facilities and expertise;

2.A better trained and wider user base with knowledge and skills in light source use in the Middle East and neighbouring countries;

3.Visibility of SESAME and stronger membership base in the Middle East for SESAME;

4.Increased scientific capacity in the Middle East;

5.Development of a community of light source aware African researchers, engineers and technicians;

6.Stronger international role of the EU’s light sources, through enhanced collaboration with Middle East and African researchers;

7.Increased capacity to address societal challenges with a global dimension.

Scope:

This topic aims at strengthening the scientific capacity and service provision of the SESAME light source and strengthening its position as an international research infrastructure and excellence hub in the Middle East and beyond, through networking and collaboration with EU-based facilities and enlarging its user base.

This topic contributes to fostering the international dimension of European research infrastructures, through their engagement with facilities and user communities in other world regions.

This activity will:

1.Foster existing and new scientific user communities in the Middle East and neighbouring regions to exploit the facilities available at SESAME. This will be achieved through mobility and training schemes, both for junior and more senior researchers and RI staff;

2.Promote outreach and visibility of the SESAME light source in the Middle East and beyond. Activities should include in-person fora and workshops with high-level stakeholder representatives;

3.Strengthen scientific services and capabilities of the SESAME beamline portfolio. Activities should include secondment of EU experienced light source staff specialists (scientists, engineers, technicians) to SESAME. Attention will be paid to improving workflows and data management on the beamlines, setting up remote access systems, enabling more diverse science through sample conditioning and environments and supporting the hands-on training of the SESAME user communities;

4.Capacity and skills building for African researchers. Activities should include workshops, mobility and access support programmes to SESAME and European light source facilities.

The proposal should convincingly be able to demonstrate significant efforts towards assuring the longer-term sustainability of SESAME and exploit its potential to support capacity building in Africa. Africa may be the origin of new SESAME user communities and will acquire experience in light source use and operation.

The proposal should build on previous EU-funded work through grants OPEN SESAME, BEATS and SUNSTONE.

The conditions are described in General Annex B.

The following exceptions apply: Legal entities established in non-associated third countries may exceptionally participate in this Coordination and support action as beneficiaries (or affiliated entities).

Due to the scope of this topic, legal entities established in non-associated third countries are exceptionally eligible for Union funding.

Legal entities:

ALBA-CELLS, Consorcio para la construcción, equipamiento y explotación el laboratorio de luz sincrotrón, Carrer de la Llum 2-26 68, 08290, Cerdanyola de Valles, Barcelona (ES)

CYI, The Cyprus Institute, Constantinou Kavafi 20 000, 2121, Nicosia (CY)

DESY, Stiftung Deutsches Elektronen - Synchrotron DESY, Notkestrasse 85, 22607, Hamburg (DE)

ELETTRA, Sincrotrone Trieste SCPA, SS 14 km 163.5 Area Science Park, 34149, Basovizza Trieste (IT)

ESRF, European Synchrotron Radiation Facility, 71 Avenue Des Martyrs, 38000 Grenoble (FR)

INFN, Istituto Nazionale di Fisica Nucleare, Via Enrico Fermi 54, 00044, Frascati (IT)

LEAPS AISBL (BE)

LUNDS UNIVERSITET, Paradisgatan 5c 117, 22100, LUND (SE)

PAUL SCHERRER INSTITUTE, Forschungstrasse 111 000, 5232, VILLIGEN PSI (CH)

SESAME, Synchrotron-Light for Experimental Science and Applications in the Middle East, Princess Rahma University College, Al-Salt Greater Municipa, Allan (JO)

SOLEIL, Synchrotron Soleil Société Civile, L’Orme des Merisiers 000, 91190, Saint Aubin (FR)

UNIWERSYTET JAGIELLONSKI, Ul Golebia 24 000, 31-007, Krakow (PL)

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Second quarter 2027

Indicative budget: EUR 1.50 million from the 2027 budget

Specific Grant Agreements to the FPA

1. SGA to the FPA for Research and Education Networks (2027)

The consortium under the selected Framework Partnership Agreement (FPA) for Research and Education Networks (HORIZON-INFRA-2021-NET-01-FPA) is invited to submit a proposal for a Specific Grant Agreement (SGA-RIA) covering the FPA final period. Activities should align with the FPA objectives and action plan. Proposals shall be evaluated in accordance with the action’s specific conditions and the requirements set forth in the Commission’s invitation letter.

Expected Outcomes:

The concrete expected outcomes per area of activities should be:

Increase core network capacity and coverage:

1.Progress towards delivering low-latency, Terabit-scale connectivity to meet evolving demand for secure network resources and underpin Europe’s digital science and computational infrastructures over the coming decade. Strengthen resilience by establishing uniform connectivity, ensuring multiple diverse routes to interconnect each Point of Presence (PoP) and minimize the risk of isolation.

2.Further develop the fibre-optic backbone to the edges of Europe, adopting dark-fibre or spectrum solutions where technically and economically feasible, to ensure seamless, high-capacity connectivity. Incorporate scalable network equipment and robust topologies capable of handling extreme data volumes, enabling effective collaboration on large-scale scientific initiatives.

Improve and expand connectivity and collaboration service catalogue offering:

1.Continue to enhance mature above-the-net-services, including the use of the underlying connectivity infrastructure and its core building blocks, security and authentication and authorisation Infrastructure (AAI), integrating cloud-based frameworks and adopting AI/ML-driven solutions where relevant.

2.Advance by designing and implementing new demand-driven, reliable, secure, and multi-domain services for GÉANT’s R&E community. Focus on meeting the needs of data-intensive research across different domains (e.g., AI, advanced analytics) while maintaining smooth interconnections with other large-scale data environments.

3.Continue strengthening interoperable frameworks and services for data-centric collaboration and sharing in line with findable, accessible, interoperable, and reusable (FAIR) principles. Evaluate emerging approaches to enhance the transparency and traceability of data exchanges, ensuring reliable and efficient data sharing across Europe’s R&E ecosystem.

Leverage Trust and Identity Services:

1.Continue extending interoperability to public and private digital identity platforms by consolidating ongoing eIDAS integration efforts (including advanced group access rights management).

2.Further contribute to national, European and global standardisation and regulation of trust and identity services to maximise the impact of privacy-by-design and sustainable solutions developed in the R&E community; align with evolving data protection regulations and adopt best practices for robust and compliant identity management.

3.Collaborate with Trust & Identity Services and standards in the public sector to continue developing interoperable solutions that uphold privacy by design and a robust trust framework across Europe.

Take GÉANT's network and partners security to the next level:

1.Enhance GÉANT's network resilience by continuously updating and integrating robust practices and validated solutions—both tailored off-the shelf or developed in-house - to ensure the security of high‑speed networks across the entire NREN community, while leveraging mature solutions and further advancing emerging approaches - such as AI‑driven threat detection and adaptive monitoring - to effectively address evolving cybersecurity challenges.

2.Adopt and evolve a next-generation framework for fast, federated incident responses across European NRENs and GÉANT, integrating automation, machine learning threat intelligence, dynamic orchestration, and regular simulations. Deepen cooperation with global Computer Emergency Response Teams (CERTs) and Computer Security Incident Response Teams (CSIRTs), to deliver innovative threat management.

3.Provide partner organisations with an extensive training program—for experts and non-experts—to enhance their security posture and respond promptly to threats, while building on existing dashboards to create a dedicated NREN security compliance mechanism for real-time standards monitoring.

4.Embed robust security principles into every stage of activity design and execution. Continuously invest in innovative security methodologies emerging from both industrial and commercial sectors to address evolving challenges such as AI-driven threats, quantum risks, and supply chain vulnerabilities.

5.Ensure GÉANT's network remains secure for processing sensitive and GDPR-compliant data, while proactively managing risks to adapt to evolving threats and regulatory requirements.

Develop collaboration in new fronts:

1.Establish and maintain a project‑wide framework for software service releases that incorporates the latest industry standards for quality, maintenance, and deployment, ensuring coherence and applicability across the entire GÉANT community collaboration. Define robust interface specifications to ensure seamless integration and ongoing interoperability of all delivered services.

2.Ensure safe, secure, and cost‑effective service delivery through pan‑European procurement frameworks. This includes maintaining an up‑to‑date, collectively managed portfolio of commercial infrastructure‑cloud platforms—such as those established under the OCRE2024 framework—to provide European research and education institutions with state‑of‑the‑art, future‑proof cloud services that uphold digital autonomy and data sovereignty.

3.Leverage the NREN federation as an open pan‑European platform for collaborative development, proof‑of‑concept trials, rigorous testing, and deployment of advanced research technologies and services—such as Fibre Acoustic Sensing, SMART Cables, Time and Frequency networks, and Quantum Communication Infrastructure—to foster innovation and enhance research collaboration.

4.Advance global connectivity and foster Europe’s international cooperation by enhancing competitiveness, digital autonomy, resilience, and security—while supporting a sustainable, high-performance digital transformation for research and education.

Expected impact:

The proposals should set out a credible pathway to contributing to all the following impacts:

1.State-of the art, uniform dark-fibre and spectrum-based backbone networks, are deployed and maintained across all NRENs, providing equitable, resilient, and ubiquitous secure connectivity across Europe to its edges, and enabling seamless connection beyond Europe with the global research and education community; sustainable, green IT principles are embedded into hardware procurement and infrastructure design.

2.Advanced AI/ML solutions are adopted to enhance network automation and service orchestration ensuring detailed, real-time visibility, managing exponential traffic growth from new devices and services, and reducing downtime and repair intervals, all while supporting data-intensive research workflows.

3.GÉANT’s advanced connectivity, trust, and security infrastructures are leveraged enabling robust, scalable cross-sectoral research collaboration and accelerating Europe's digital transformation; cybersecurity resilience is scaled up by advancing AI-driven cybersecurity frameworks and federated incident response mechanisms, complemented by robust identity solutions (eduGAIN and eIDAS).

4.Europe’s research and education networks are at the forefront of the fast-evolving landscape on quantum, AI, HPC, cloud, time and frequency networks (TFN) and other new technologies enabling network innovations.

5.Cloud infrastructures are expanded and consolidated under the Open Clouds for Research Environments (OCRE) initiative, ensuring comprehensive and secure data orchestration, and cloud service frameworks, to effectively reduce reliance on non-European service providers while reinforcing Europe's digital sovereignty.

6.GÉANT’s incubator pathways are expanded through bottom-up experimentation and user-centric approach to sustain and drive European innovation capacity; and tools and services based on emerging technologies, such as distributed acoustic sensing, quantum-based tools and integrated HPC solutions are evaluated and, where appropriate, operationalised.

7.The governance, decision-making, multi-stakeholder coordination frameworks, and strategic oversight of GÉANT are streamlined to maintain agile and continuous engagement among all NRENs.

8.Europe's global connectivity leadership is supported through international research collaboration.

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes.

Specific conditions:

6-years Framework Partnership Agreement for Research and Education Networks with identified beneficiary and specific grants awarded to identified beneficiary for Research and Innovation Action under the Framework Partnership Agreement.

In this action the integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement.

Purchases of equipment, infrastructure, services or other assets used for the action must be declared as depreciation costs.

Equipment, infrastructure, services or other assets (such as IRUs) purchased specifically for the action (or developed as part of the action tasks) may exceptionally be declared as full capitalised costs taking into account that their life span may extend after the duration of the action and beyond the FPA coverage.

The standard evaluation criteria, thresholds, weighting for award criteria and the maximum rate of co-financing for this type of action are provided in parts D and G of the General Annexes. with the following exceptions for the evaluation criteria:

“The following additions to the general award criteria apply:

For the criterion Excellence:

1.Clarity and pertinence of the project’s objectives, including their relevance to the overarching goals of the FPA. Extent to which the proposed work is ambitious, and goes beyond the state-of-the-art.

2.Soundness of the proposed methodology, including the business model approach on service delivery and provision of innovative services and the related metrics.

3.Effectiveness and agility in developing new services according to the needs of a wide user base across multiple disciplines for excellent science and research.

Eligibility conditions: The conditions are described in General Annex B. The following exceptions apply: Subject to restrictions for the protection of European communication networks.

Form of Funding: Grants not subject to calls for proposals

Type of Action: Specific grant agreement awarded without call for proposals in relation to a Framework Partnership Agreement

Indicative timetable: First quarter 2027

Indicative budget: EUR 60.00 million from the 2027 budget

Expert contract actions

1. External expertise 2026

This action will support:

1.The use of appointed independent experts for the evaluation and monitoring of actions (grant agreement, grant decision, public procurement actions, financial instruments, evaluation) funded under Horizon Europe and previous Framework Programmes for Research and Innovation and where appropriate, include ethics checks as well as compliance checks regarding the Gender Equality Plan eligibility criterion. A special allowance of EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest.

2.The use of individual experts to advise on, or support, the design and implementation of EU policies on research infrastructures. The activities carried out by the experts will be essential to the development and monitoring of the Union policy and initiatives in this area. The individual experts' tasks will include attending bilateral meetings with Commission services, remote drafting and possible preparatory work. The experts will be highly qualified, specialised, independent experts selected on the basis of their competence and knowledge of the field. A special allowance of EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest. This amount is considered to be proportionate to the specific tasks to be assigned to the experts, including the number of meetings to be attended and possible preparatory work.

3.The use of individual experts for the assessment of ERIC applications, as required under the ERIC Regulation 125 . The experts will be highly qualified independent experts selected on the basis of their specific competence. The experts will provide a report for each of the assessed ERIC application. A special allowance of EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest. This amount is considered to be proportionate to the specific tasks to be assigned to the experts.

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative budget: EUR 0.40 million from the 2026 budget

2. External expertise 2027

This action will support:

1.The use of appointed independent experts for the evaluation and monitoring of actions (grant agreement, grant decision, public procurement actions, financial instruments, evaluation) funded under Horizon Europe and previous Framework Programmes for Research and Innovation and where appropriate, include ethics checks as well as compliance checks regarding the Gender Equality Plan eligibility criterion. A special allowance of EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest.

2.The use of individual experts to advise on, or support, the design and implementation of EU policies on research infrastructures. The activities carried out by the experts will be essential to the development and monitoring of the Union policy and initiatives in this area. The individual experts' tasks will include attending bilateral meetings with Commission services, remote drafting and possible preparatory work. The experts will be highly qualified, specialised, independent experts selected on the basis of their competence and knowledge of the field. A special allowance of EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest. This amount is considered to be proportionate to the specific tasks to be assigned to the experts, including the number of meetings to be attended and possible preparatory work.

3.The use of individual experts for the assessment of ERIC applications, as required under the ERIC Regulation 126 . The experts will be highly qualified independent experts selected on the basis of their specific competence. The experts will provide a report for each of the assessed ERIC application. A special allowance of EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest. This amount is considered to be proportionate to the specific tasks to be assigned to the experts.

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative budget: EUR 0.60 million from the 2027 budget

Procurement

1. Managed services for the EOSC Platform (EOSC EU Node)

This procurement action will ensure the continuous improvement, operations, maintenance and support of the managed services for the EOSC EU Node 127 platform, providing access to a rich portfolio of FAIR data and professional quality FAIR services in all relevant domains from data handling to computing, processing, analysis and storing.

The infrastructure should be robust, secure, scalable, flexible and user-centric. It is constantly improved and upgraded following user feedback and the state-of-the-art of the underlying core technologies. It offers high quality of service management compliant with industrial standards, providing for a superior user experience, usability and ease of use for a very large number of users (i.e. hundreds of parallel user sessions per day), with the functionalities available 24/7. It offers seamless access to data, software and services through customized user interfaces, allowing users to navigate with built-in guidance tools and analytics for (re)use and service composition. It builds on the key concept of federation, standards and processes for Open Science, such as the EOSC Interoperability Framework and FAIR-by-design data and services.

Expected Results:

1.Continuously operational, secure cloud-based EOSC infrastructure (EOSC EU Node) offering high quality professional services available 24/7.

2.Rich set of innovative, modular, customizable and composable services for a wide variety of users from the research communities and beyond.

3.A large number of data and service communities aligned in terms of standards and consolidated at subdomain, domain and interdisciplinary levels.

4.Established links with Common European Data Spaces via Simpl 128 and with the HPC federation 129 .

5.Increased discovery and reuse of European research output as a result of FAIR data and services provided through EOSC, and cross-fertilization and a wider sharing of knowledge and technologies.

Form of Funding: Procurement

Type of Action: Public procurement

Indicative timetable: Second quarter 2026

Indicative budget: EUR 14.50 million from the 2026 budget

2. Support for EOSC EU Node Service Verification and Validation activities

In close collaboration with other Commission services and its customers, the Operating DG/Unit builds and operates solutions for a fully operational enabling infrastructure for EOSC – referred to as the EOSC EU Node – providing access to a rich portfolio of FAIR (Findable, Accessible, Interoperable, Reusable) data and professional quality interoperable services in all relevant domains from data handling to computing, processing, analysis and storing.

The main tasks for the external contractors are on one hand to support the Operating DG/Unit internally managing the service delivery, deployment and operations with special focus on the IT Governance process of the Commission and relevant policy and security compliance tasks, and on the other hand to monitor the third-party contractors directly, verifying and validating the services delivered against KPIs, SLR/SLA requirements (fit for use), as well as users’ needs (fit for purpose).

Expected Outcome:

The requested personnel of the external service provider shall contribute to the evaluation and validation of the service components against the defined requirements and agreed roadmaps, verification and validation of the service, and system integration against defined industry standards and EOSC Platform specifications (upon which the EOSC EU Node has been built), examination of outputs produced by the implementation Contractor(s) as well as testing activities to confirm that system components are functional as designed.

Form of Funding: Procurement

Type of Action: Public procurement

Indicative timetable: Second quarter 2026 & second quarter 2027

Indicative budget: EUR 1.00 million from the 2026 budget and EUR 1.00 million from the 2027 budget

Specific Features For Research Infrastructures

This section provides further conditions and requirements on access provision that applicants must comply with, for different topics under the INFRASERV destination of the Research Infrastructures work programme. Compliance with these provisions will also be taken into account during evaluation. These provisions may also apply to topics with an access component under other destinations of this Work Programme, with indication, where relevant, of any deviation from these specific features.

Trans-national and/or virtual access 130 activities.

Trans-national access activities

Trans-national access provision must be implemented as follows:

Trans-national access to infrastructure services offered under the grant is provided 'free of charge' to selected researchers or research teams (user-groups) including from industry. Access activities should be implemented in a coordinated way so as to improve the overall service provision to the research community. Access may be made available to external users, either in person (‘hands-on’), when the user visits the infrastructure to make use of it, or through the provision to the user of remote scientific services, such as the provision of reference materials or samples, the remote access to a high-performance computing facility, the performance of sample analysis or sample deposition.

The research infrastructures must publicise widely the access offered under the grant agreement to ensure that researchers who might wish to have access to the infrastructures are made aware of the possibilities open to them. They must open specific calls to invite researchers to apply for access. The research infrastructures must promote equal opportunities in advertising the access and take into account gender issues when defining the support provided to visitors. They must maintain appropriate documentation to support and justify the amount of access reported. This documentation must include records of the names, nationalities, and home institutions of the users within the research teams, as well as the nature and quantity of access provided to them. To this extent, a unit of access to each infrastructure service/installation 131 needs to be identified and precisely defined in the proposal.

The selection of researchers or research teams must be carried out through an independent peer-review evaluation of the research projects (user projects) they wish to carry out at the infrastructure. The research team, or its majority, must work in countries other than the country(ies) where the infrastructure is located (when the infrastructure is composed of several research facilities, operated by different legal entities, this condition must apply to each facility) except when access is provided by an International organisation, the Joint Research Centre (JRC), an ERIC or similar legal entities with international membership. User teams where all or the majority of users work in third countries can be supported as long as the cumulative access provided to them is below 20% of the total amount of units of access provided under the grant. In exceptional and well justified cases a higher percentage of access to third-country user teams can be set out in the proposal.

Only user groups that are allowed to disseminate the results they have generated under the action may be eligible for access (unless the users are working for SMEs).

The duration of stay at a research infrastructure must normally be limited to three months, unless otherwise provided for in the proposal.

The EU financial support to trans-national access will cover the access costs 132 incurred by the access provider in providing access to the selected researchers, as well as the travel and subsistence costs incurred in supporting visits to the infrastructure of these researchers.

The access costs charged to the grant will not include capital investments (including depreciation costs of equipment, infrastructure or other assets) nor internally invoiced goods and services, unless otherwise specified in the work programme, while they may cover the running costs of the infrastructure as well as the cost for the logistical, technological and scientific support for users’ access. This includes costs for ad-hoc training users need to use the infrastructure and for preparatory and closing activities that may be necessary to carry out users’ work on the infrastructure.

Virtual access activities

Virtual access provision must be implemented as follows:

Virtual access to research infrastructure is provided through communication networks to users complying with the RI’s access policy, without selecting them. Examples of virtual access activities are provision of access to databases available via Internet, or data deposition services.

The research infrastructures must publicise widely the access offered under the grant agreement to ensure that researchers who might wish to have access to the infrastructures are made aware of the possibilities open to them.

The EU financial support to virtual access will cover the access costs 133  incurred by the infrastructure in providing access under the project, including the technological and scientific support researchers need to effectively use the services. Capital investments (including depreciation costs of equipment, infrastructure or other assets) as well as internally invoiced goods and services will not be eligible costs unless otherwise specified under the specific call or topic, in which case only the portion used to provide virtual access under the project can be eligible. A unit of access to each research infrastructure service must be identified and precisely defined in the proposal. The provision of virtual access during the project lifetime will be measured through the units of access defined in the grant agreement and must be periodically assessed by an external board. Eligibility criteria (e.g. affiliation to a research or academic institution) for users can be defined in the proposal, to take into account the access policies of the different RIs.

Budget 134

Budget line(s)

2026 Budget (EUR million)

2027 Budget (EUR million)

Calls

HORIZON-INFRA-2026-01

294.90

from 01.020103

294.90

HORIZON-INFRA-2027-01

339.50

from 01.020103

339.50

Other actions

Grant awarded without a call for proposals according to Financial Regulation Article 198(e)

0.40

5.60

from 01.020103

0.40

5.60

Specific grant agreement

60.00

from 01.020103

60.00

Expert contract action

0.40

0.60

from 01.020103

0.40

0.60

Public procurement

15.50

1.00

from 01.020103

15.50

1.00

Estimated total budget

311.20

406.70

(1)    Sustainable refers to the overall “capacity for a research infrastructure to remain operative, effective and competitive over its expected lifetime”. This also encompasses the environmental and resources footprint dimensions.
(2)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=COM:2025:497:REV1
(3)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex:52025DC0270
(4)    See e.g. topics 2026-DEV-01-02, 2026-DEV-01-04, 2026-TECH-01-01, 2027-TECH-01-01.
(5)    See e.g. topics 2026-SERV-01-01, 2026-01-EOSC-01, 2026-TECH-01-02, 2027-TECH-01-02.
(6)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52025DC0525
(7)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex:52024DC0098
(8)    See e.g. topics 2026-DEV-01-02, 2027-SERV-01-01 and 2027-SERV-01-02.
(9) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(10)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(11) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(12)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(13)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(14)    A research infrastructure is of European interest when is able to attract users from EU or associated countries other than the country where the infrastructure is located.
(15)    Unlike a major upgrade or extension, the research infrastructure complemented by its new component is not equivalent to a new infrastructure concept and is not transformative enough to qualify as the next generation of research infrastructure of European interest
(16)    This option considers a new concept, which could develop independently and would qualify, alone, as a next generation of research infrastructure of European interest but which, for the sake of sustainability and consolidation of the European landscape of research infrastructures, would benefit from developing by extending or integrating into an existing research infrastructure.
(17)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/european-partnerships-horizon-europe_en#what-are-european-partnerships
(18)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(19)    ESFRI domains: 1. Data, Computing and Digital Research Infrastructures; 2. Energy; 3. Environment; 4. Health & Food; 5. Physical Sciences and Engineering; 6. Social Sciences & Humanities. See ESFRI Landscape Analysis 2024 https://landscape2024.esfri.eu/ .
(20)     Implementation and operation of cross-cutting services and solutions for clusters and Connecting ESFRI infrastructures through Cluster projects .
(21)    Preparation of common strategies for future development of RI technologies and services within broad RI communities – https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2023-DEV-01-05/en
(22)    Research infrastructure services to enable R&I addressing main challenges and EU priorities and advancing frontier knowledge - cordis link
(23)     https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2025-01-DEV-05
(24)    See the list of ESFRI 'Landmarks' in the 2021 ESFRI Roadmap on https://roadmap2021.esfri.eu/ For ESFRI Landmarks that are not an ERIC or an international European research organisation, the beneficiary must be the legal entity hosting the infrastructure in the lead country (such legal entity is a minimum requirement to become an ESFRI Landmark).
(25)     European Research Infrastructure Consortium (ERIC) | European Commission (europa.eu)
(26)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(27)    See list of ESFRI Landmarks in the ESFRI RIs PORTFOLIO https://ri-portfolio.esfri.eu/
(28)    See ERIC Landscape – Active European Research Infrastructure Consortia (ERICs) https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/our-digital-future/european-research-infrastructures/eric/eric-landscape_en
(29)    Although the action aims at individual support to a pan-European research infrastructure, applicants should consider the ESFRI Landscape Analysis and liaise during the action with other relevant ESFRI/ERICs to ensure complementarity https://landscape2024.esfri.eu/ .
(30)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(31)    RItrainPlus - RESEARCH INFRASTRUCTURE TRAINING PLUS https://cordis.europa.eu/project/id/101008503
(32)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(33)    EURIZON - European network for developing new horizons for RIs https://cordis.europa.eu/project/id/871072
(34)    See the list of ESFRI 'Landmarks' in the 2021 ESFRI Roadmap on https://roadmap2021.esfri.eu/ For ESFRI Landmarks, that are not an ERIC or an international European research organisation, the beneficiary must be the legal entity hosting the infrastructure in the lead country (such legal entity is a minimum requirement to become an ESFRI Landmark).
(35)     European Research Infrastructure Consortium (ERIC) | European Commission (europa.eu)
(36)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(37)    ESFRI RIs PORTFOLIO https://ri-portfolio.esfri.eu/ and ERIC Landscape – Active European Research Infrastructure Consortia (ERICs) https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/our-digital-future/european-research-infrastructures/eric/eric-landscape_en
(38)     https://www.gsogri.org/
(39)     Council Recommendation of 23 May 2024 on enhancing research security
(40)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(41)    ESFRI RIs PORTFOLIO https://ri-portfolio.esfri.eu/
(42)    ERIC Landscape – Active European Research Infrastructure Consortia (ERICs) https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/our-digital-future/european-research-infrastructures/eric/eric-landscape_en
(43)    ESFRI Report on Energy and Supply Challenges of Research Infrastructures ESFRI Report on Energy and Supply Challenges of Research Infrastructures | www.esfri.eu
(44)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(45)    See the list of ESFRI 'Landmarks' in the 2021 ESFRI Roadmap on https://roadmap2021.esfri.eu/ For ESFRI Landmarks that are not an ERIC or an international European research organisation, the beneficiary must be the legal entity hosting the infrastructure in the lead country (such legal entity is a minimum requirement to become an ESFRI Landmark).
(46)     European Research Infrastructure Consortium (ERIC) | European Commission (europa.eu)
(47)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(48)    A research infrastructure is of European interest when it is able to attract users from EU or associated countries other than the country where the infrastructure is located.
(49)    Such as under topic HORIZON-INFRA-2023-DEV-01-04: Consolidation of the RI landscape – development of complementarities, synergies and/or integration between a set of pan- European research infrastructures https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2023-DEV-01-04/en
(50)    See the list of ESFRI 'Landmarks' in the 2021 ESFRI Roadmap on https://roadmap2021.esfri.eu/ For ESFRI Landmarks that are not an ERIC or an international European research organisation, the beneficiary must be the legal entity hosting the infrastructure in the lead country (such legal entity is a minimum requirement to become an ESFRI Landmark).
(51)     European Research Infrastructure Consortium (ERIC) | European Commission (europa.eu)
(52)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(53)    Although the action aims at individual support to a pan-European research infrastructure, applicants should consider the ESFRI Landscape Analysis and liaise during the action with other relevant ESFRI/ERICs to ensure complementarity.
(54)    https://eosc.eu/eosc-about/sria-mar/
(55)    https://interoperable-europe.ec.europa.eu/collection/eupl/eupl-text-eupl-12
(56)    https://www.gnu.org/licenses/license-list#SoftwareLicenses
(57)    https://opensource.org/licenses
(58)    Relevant information and documentation about the EOSC Federation can be found in the EOSC Federation Handbook and other relevant documentation adopted by the EOSC Federation.
(59)    As described in the EOSC Federation Handbook and other relevant documentation potentially adopted by the EOSC Federation.
(60)    Including reasonable administrative and management costs related to the open calls for the financial support to third parties.
(61)    https://eosc.eu/partnership/
(62)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(63)    As described in the EOSC Federation Handbook and other relevant documentation potentially adopted by the EOSC Federation
(64)    https://eosc.eu/partnership/
(65)    As described in the EOSC Federation Handbook and other relevant documentation potentially adopted by the EOSC Federation.
(66)    https://eosc.eu/partnership/
(67)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(68)    https://research-and-innovation.ec.europa.eu/research-area/industrial-research-and-innovation/eu-valorisation-policy/knowledge-valorisation-platform
(69)    http://data.europa.eu/eli/reco/2023/499/oj
(70)    https://eur-lex.europa.eu/eli/reco/2023/498/oj
(71)    https://eosc.eu/partnership/
(72)     https://op.europa.eu/publication-detail/-/publication/ec4692ae-ac6f-11ef-acb1-01aa75ed71a1
(73)    ESFRI domains: 1. Data, Computing and Digital Research Infrastructures; 2. Energy; 3. Environment; 4. Health & Food; 5. Physical Sciences and Engineering; 6. Social Sciences & Humanities. See ESFRI Landscape Analysis 2024 https://landscape2024.esfri.eu/ .
(74)    A research infrastructure is of European interest when is able to attract users from EU or associated countries other than the country where the infrastructure is located. This includes ESFRI and ERIC infrastructures.
(75)    See lists of ESFRI 'Landmarks‘ in the 2021 ESFRI Roadmap on https://roadmap2021.esfri.eu/
(76)     European Research Infrastructure Consortium (ERIC) | European Commission (europa.eu)
(77)    See the Eligibility conditions for this topic.
(78)    “Installation” means a part or a service of a research infrastructure that can be used independently from the rest. A research infrastructure consists of one or more installations.
(79)     https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2025-01-DEV-05
(80)     https://op.europa.eu/publication-detail/-/publication/ec4692ae-ac6f-11ef-acb1-01aa75ed71a1
(81)    A research infrastructure is of European interest when is able to attract users from EU or associated countries other than the country where the infrastructure is located. This includes ESFRI and ERIC infrastructures.
(82)    See ESFRI Landmarks in ESFRI RIs PORTFOLIO https://ri-portfolio.esfri.eu/ and ERIC Landscape – Active European Research Infrastructure Consortia (ERICs) https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/our-digital-future/european-research-infrastructures/eric/eric-landscape_en.
(83)    The term ‘distributed’ research infrastructure typically refers to one or a few central hubs and several interlinked (national or institutional) nodes where many components of the research infrastructure may not be part of the same legal entity, the ERIC. A declaration signed by the legal representative of the ERIC should confirm that the ERIC is supporting this participation, explain the relevance for the ERIC and describe any further cooperation with the ERIC.
(84)    See the Eligibility conditions for this topic.
(85)    “Installation” means a part or a service of a research infrastructure that can be used independently from the rest. A research infrastructure consists of one or more installations.
(86)     https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2025-01-DEV-05
(87)     https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2021-SERV-01-02
(88)     https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2023-SERV-01-01
(89)     https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2021-SERV-01-04
(90)     https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2023-SERV-01-01
(91)    See the list of ESFRI 'Landmarks' in the 2021 ESFRI Roadmap on https://roadmap2021.esfri.eu/ For ESFRI Landmarks that are not an ERIC or an international European research organisation, the beneficiary must be the legal entity hosting the infrastructure in the lead country (such legal entity is a minimum requirement to become an ESFRI Landmark).
(92)     European Research Infrastructure Consortium (ERIC) | European Commission (europa.eu)
(93)    “Installation” means a part or a service of a research infrastructure that can be used independently from the rest. A research infrastructure consists of one or more installations.
(94)    https://platform.destine.eu/services/
(95)    Communication from the Commission to the European Parliament, the Council, the European Economic and Social Committee and the Committee of the Regions: AI Continent Action Plan ((COM(2025) 165 final of 9.4.2025).
(96)     https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2022-TECH-01-01
(97)     https://cordis.europa.eu/programme/id/HORIZON_HORIZON-INFRA-2024-TECH-01-01
(98)    The participation of two nodes of the same ESFRI infrastructure or ERIC does not count as two different research infrastructures.
(99)    See the list of ESFRI 'Landmarks' and ‘Projects’ in the 2021 ESFRI Roadmap: https://roadmap2021.esfri.eu/
(100)     European Research Infrastructure Consortium (ERIC) | European Commission (europa.eu)
(101)    An ‘international European research organisation' means an international organisation, the majority of whose members are Member States or associated countries, whose principal objective is to promote scientific and technological cooperation in Europe.
(102) 'Pre-commercial procurement' is defined as procurement of R&D services involving risk-benefit sharing under market conditions and competitive development in phases. PCP focuses on the R&D phase before wide commercialisation.'Risk-benefit sharing under market conditions' refers to the PCP approach in which procurers share with suppliers at market price the risks and the benefits related to the IPR resulting from the R&D.'Competitive development in phases' refers to the competitive approach to buy the R&D from several competing R&D providers in parallel and to compare and identify the best value for money solutions on the market to address the PCP challenge. To reduce the investment risk for the procurer, reward the most competitive solutions and facilitate the participation of smaller innovative companies, the R&D is also split into phases (solution design, prototyping, original development and validation / testing of the first products), with the number of competing R&D providers being reduced after each phase.    
(103)    https://platform.destine.eu/
(104)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(105)    AI Continent Action Plan, COM(2025)165 of 9 April 2025
(106)     https://www.satcen.europa.eu/
(107)    https://digital-strategy.ec.europa.eu/en/policies/data-spaces
(108)    See the list of ESFRI 'Landmarks' and ‘Projects’ in the 2021 ESFRI Roadmap: https://roadmap2021.esfri.eu/
(109)     European Research Infrastructure Consortium (ERIC) | European Commission (europa.eu)
(110)    An ‘international European research organisation' means an international organisation, the majority of whose members are Member States or associated countries, whose principal objective is to promote scientific and technological cooperation in Europe
(111)    For ESFRI Landmarks that are not an ERIC or an international European research organisation, the beneficiary must be the legal entity hosting the infrastructure in the lead country (such legal entity is a minimum requirement to become an ESFRI Landmark). For ESFRI Projects without an established legal entity, the beneficiary must be a legal entity from the lead country, typically the one coordinating the development of the ESFRI Project.
(112)    'Pre-commercial procurement' is defined as procurement of R&D services involving risk-benefit sharing under market conditions and competitive development in phases. PCP focuses on the R&D phase before wide commercialisation. 'Risk-benefit sharing under market conditions' refers to the PCP approach in which procurers share with suppliers at market price the risks and the benefits related to the IPR resulting from the R&D. 'Competitive development in phases' refers to the competitive approach to buy the R&D from several competing R&D providers in parallel and to compare and identify the best value for money solutions on the market to address the PCP challenge. To reduce the investment risk for the procurer, reward the most competitive solutions and facilitate the participation of smaller innovative companies, the R&D is also split into phases (solution design, prototyping, original development and validation / testing of the first products), with the number of competing R&D providers being reduced after each phase.
(113)    https://platform.destine.eu/
(114)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(115)    AI Continent Action Plan COM(2025)165 of 9 April 2025
(116)    https://digital-strategy.ec.europa.eu/en/policies/data-spaces
(117)     https://www.eric-forum.eu/
(118)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/our-digital-future/european-research-infrastructures/eric_en
(119)     https://op.europa.eu/publication-detail/-/publication/cdbe5c78-353b-11ec-bd8e-01aa75ed71a1
(120)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=COM:2023:488:FIN
(121)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(122)    https://cordis.europa.eu/project/id/101188045
(123)    EOSC United includes activities that ‘help shaping the EOSC Federation governance and operational framework’.
(124)    EOSC Gravity includes activities that ‘support the transition of the European co-programmed Partnership for EOSC into its new governance and funding framework’.
(125)    Council Regulation (EC) No 723/2009 of 25 June 2009 on the Community Legal Framework for a European Research Infrastructure Consortium.
(126)    Council Regulation (EC) No 723/2009 of 25 June 2009 on the Community Legal Framework for a European Research Infrastructure Consortium.
(127)    https://open-science-cloud.ec.europa.eu/
(128)    Simpl programme: https://simpl-programme.ec.europa.eu/
(129)    HPC federation: https://www.eurohpc-ju.europa.eu/paving-way-eurohpc-federation-platform-2024-12-19_en
(130)    See Article 18 and Annex 5 of Horizon Europe Model Grant Agreement
(131)    “Installation” means a part or a service of a research infrastructure that can be used independently from the rest. A research infrastructure consists of one or more installations.
(132)    Access costs will be supported through the reimbursement of the eligible costs specifically incurred by a research infrastructure for providing access to the research teams selected for support under the project, or on the basis of unit costs calculated according to the methodology indicated in the Decision of 5 May 2022, authorising the use of unit costs for the costs of providing trans-national and virtual access in Research Infrastructures actions under the Horizon Europe Programme. In the latter case the access costs will be calculated multiplying the unit cost by the quantity of access provided under the grant. The cost of the unit of access to the infrastructure, i.e. the unit cost, must then be indicated in the proposal. A combination of the two methods mentioned above will also be possible.
(133)    Access costs will be supported through the reimbursement of the eligible actual costs specifically incurred by a research infrastructure for providing virtual access to identified users under the project, or on the basis of unit costs calculated according to the methodology indicated in the Decision of 5 May 2022, authorising the use of unit costs for the costs of providing trans-national and virtual access in Research Infrastructures actions under the Horizon Europe Programme. In the latter case, the access costs will be calculated multiplying the unit cost by the quantity of access provided under the grant. The cost of the unit of access to the research infrastructure, i.e. the unit cost, must then be indicated in the proposal. A combination of the two methods mentioned above will also be possible.
(134) The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The budget figures given in this table are rounded to two decimal places.
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EN

Annex IV

Horizon Europe

Work Programme 2026-2027

4. Health

Table of contents

Introduction    

Calls    

Call - Cluster 1 - Health (Single stage - 2026)    

Overview of this call    

Call - Partnerships in Health (2026/1)    

Overview of this call    

Call - Partnerships in Health (2026/2)    

Overview of this call    

Call - Partnerships in Health (2026/3)    

Overview of this call    

Call - Cluster 1 - Health (Single stage - 2027/1)    

Overview of this call    

Call - Cluster 1 - Health (Two stage - 2027)    

Overview of this call    

Call - Cluster 1 - Health (Single stage - 2027/2)    

Overview of this call    

Destinations    

Destination - Staying healthy in a rapidly changing society    

HORIZON-HLTH-2026-01-STAYHLTH-02: Behavioural interventions as primary prevention for Non-Communicable Diseases (NCDs) among young people    

HORIZON-HLTH-2026-01-STAYHLTH-03: Building public trust and outreach in the life sciences    

HORIZON-HLTH-2027-01-STAYHLTH-01: Addressing disabilities through the life course to support independent living and inclusion    

Destination - Living and working in a health-promoting environment    

HORIZON-HLTH-2026-01-ENVHLTH-01: Towards a better understanding and anticipation of the impacts of climate change on health    

HORIZON-HLTH-2026-01-ENVHLTH-04: Towards climate resilient, prepared and carbon neutral populations and healthcare systems    

HORIZON-HLTH-2026-01-ENVHLTH-05: Support for a multilateral initiative on climate change and health research    

HORIZON-HLTH-2027-01-ENVHLTH-02: Integrating climate-related exposures into the human exposome and characterising its changes in response to climate change    

HORIZON-HLTH-2027-01-ENVHLTH-MISSCLIMA-03: Tools and technologies to support health adaptation to climate change    

Destination - Tackling diseases and reducing disease burden    

HORIZON-HLTH-2026-01-DISEASE-02: Innovative interventions to prevent the harmful effects of using digital technologies on the mental health of children and young adults    

HORIZON-HLTH-2026-01-DISEASE-03: Advancing research on the prevention, diagnosis, and management of post-infection long-term conditions    

HORIZON-HLTH-2026-01-DISEASE-04: Development of novel vaccines for viral pathogens with epidemic potential    

HORIZON-HLTH-2026-01-DISEASE-09: Multisectoral approach to tackle chronic non-communicable diseases: implementation research maximising collaboration and coordination with sectors and in settings beyond the healthcare system (GACD)    

HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways    

HORIZON-HLTH-2026-02-DISEASE-12: European Partnership on Rare Diseases (ERDERA) (Phase 2)    

HORIZON-HLTH-2026-03-DISEASE-13: European Partnership for Pandemic Preparedness (Phase 2)    

HORIZON-HLTH-2026-01-DISEASE-15: Scaling up innovation in cardiovascular health    

HORIZON-HLTH-2027-02-DISEASE-01-two-stage: Innovative healthcare interventions for non-communicable diseases    

HORIZON-HLTH-2027-01-DISEASE-05: Development of novel small molecule antiviral therapeutics for pathogens with epidemic potential    

HORIZON-HLTH-2027-01-DISEASE-06: Development of monoclonal antibodies to prevent and treat infections from Flaviviruses    

HORIZON-HLTH-2027-01-DISEASE-07: Development of monoclonal antibodies to prevent and treat infections from Filo-, Nairo-, Phenui-, Picorna- and Toga viruses    

HORIZON-HLTH-2027-01-DISEASE-08: Development of innovative antimicrobials against pathogens resistant to antimicrobials    

HORIZON-HLTH-2027-01-DISEASE-10: Prevention and management of chronic non-communicable diseases in children and young people (GACD)    

HORIZON-HLTH-2027-02-DISEASE-14-two-stage: Clinical trials for advancing innovative interventions for neurodegenerative diseases    

Destination - Ensuring equal access to innovative, sustainable, and high-quality healthcare    

HORIZON-HLTH-2026-01-CARE-01: Public procurement of innovative solutions for improving citizens' access to healthcare through integrated or personalised approaches    

HORIZON-HLTH-2026-01-CARE-03: Identifying and addressing low-value care in health and care systems    

HORIZON-HLTH-2026-04-CARE-04: Enhancing and enlarging the European Partnership on Personalised Medicine (EP PerMEd) (Top-up)    

HORIZON-HLTH-2027-01-CARE-02: Personalised approaches to reduce risks from Adverse Drug Reactions due to administration of multiple medications    

Destination - Developing and using new tools, technologies and digital solutions for a healthy society    

HORIZON-HLTH-2026-01-TOOL-03: Integrating New Approach Methodologies (NAMs) to advance biomedical research and regulatory testing    

HORIZON-HLTH-2026-01-TOOL-05: Pilot actions for follow-on funding: Leveraging EU-funded collaborative research in regenerative medicine    

HORIZON-HLTH-2026-01-TOOL-06: Support to European Research Area (ERA) action on accelerating New Approach Methodologies (NAMs) to advance biomedical research and testing of medicinal products and medical devices    

HORIZON-HLTH-2026-01-TOOL-07: Establishing a European network of Centres of Excellence (CoEs) for Advanced Therapies Medicinal Products (ATMPs)    

HORIZON-HLTH-2027-02-TOOL-01-two-stage: Development of predictive biomarkers of disease progression and treatment response by using AI methodologies for chronic non-communicable diseases    

HORIZON-HLTH-2027-03-TOOL-02: Advancing bio-printing of living cells for regenerative medicine    

HORIZON-HLTH-2027-03-TOOL-04: Virtual Human Twins (VHTs) for integrated clinical decision support in prevention and diagnosis    

HORIZON-HLTH-2027-03-TOOL-08: Towards Artificial General Intelligence (AGI) for healthcare    

Destination - Maintaining an innovative, sustainable, and competitive EU health industry    

HORIZON-HLTH-2026-01-IND-03: Regulatory science to support translational development of patient-centred health technologies    

HORIZON-HLTH-2027-01-IND-01: Development of cell-free protein synthesis platforms for discovery and/or production of biologicals    

HORIZON-HLTH-2027-02-IND-02-two-stage: Portable and versatile Point-of-care diagnostics    

Other Actions not subject to calls for proposals    

Grants to identified beneficiaries    

1. Contribution to the activities of the Coalition for Epidemics Preparedness Initiative (CEPI) in 2026    

2. Presidency event - Ireland. Bridging Worlds - Climate Change and Health through the lens of the One Health Agenda - Research, Innovation and Problem Solving    

3. Presidency event - Lithuania. Strengthening the European clinical research ecosystem for advanced therapy medicinal products and substances of human origin    

4. Contribution to the activities of the Coalition for Epidemics Preparedness Initiative (CEPI) in 2027    

5. Presidency event - Greece. Climate change and health - Aligning Research and Innovation for a resilient future (European and global perspectives)    

6. European registry for human pluripotent stem cell lines    

Other Instruments    

1. External expertise    

2. External expertise in relation to EU research and innovation policy issues    

3. Mobilisation of research funds in case of Public Health Emergencies    

4. Studies, conferences, events and outreach activities    

5. Subscription to the Human Frontier Science Program Organization    

Budget    

Introduction

This Work Programme part is the final instalment for the Health Cluster under Horizon Europe (2021-2027), representing the last opportunity to deliver on the programme's objectives. It aims to address the remaining gaps, emerging research needs, and future challenges identified in the second Horizon Europe strategic plan 1 , covering years 2025 to 2027. It also aligns with the Commission's Political Guidelines for 2024-2029 2 , which focus on strengthening healthcare resilience, leveraging biotechnology and artificial intelligence, and addressing public health needs including supporting the development of critical medicines and strengthening societal preparedness and response. This will contribute to Europe's sustainable prosperity and competitiveness. Collaboration in research and innovation is key to achieving these goals.

In 2026-2027, the Health Cluster will pursue the following priorities:

1.Contributing to the goal of making the EU the most attractive place of life sciences by 2030 and implementing the “Strategy for European Life Sciences” 3 .

2.Addressing non-communicable diseases, including mental and cardiovascular health, through prevention, treatment, and management, supporting initiatives such as the “Healthier Together” EU Non-communicable Diseases Initiative and the future EU Cardiovascular Health (CVH) plan 4 .

3.Understanding and mitigating the impacts of climate change, pollution, and biodiversity loss on human health and healthcare systems, supporting both the European Climate Adaptation Plan and the European Green Deal. This dual approach addresses the need to adapt to unavoidable climate impacts while contributing to broader mitigation efforts through transformative healthcare solutions.

4.Building pandemic preparedness and response, including addressing antimicrobial resistance, in support of the European Health Union and the European Medical Countermeasures Strategy 5 and coherent with the forthcoming Critical Medicines Act 6 .

5.Transforming Europe's healthcare systems to make them more effective, efficient, equitable, accessible, and sustainable, complementing the work of the co-funded European Partnership on Transforming Health and Care Systems 7 .

6.Supporting digitalisation in healthcare, leveraging the innovation potential of health data and data-driven approaches, including AI, in the context of the European Health Data Space (EHDS) 8 Regulation.

7.Developing and using innovative tools and critical technologies, such as AI and biotechnology, to secure a competitive EU health industry and technological sovereignty in the healthcare sector, in line with the EU's Artificial Intelligence Strategy and the “Biotechnology and Biomanufacturing Communication” 9 .

While the entire Health Cluster Work Programme contributes to the “Strategy for European Life Sciences”, the following topics directly support key actions outlined in it: i) HORIZON-HLTH-2026-01-STAYHLTH-03: “Building public trust and outreach in the life sciences”, ii) HORIZON-HLTH-2026-01-ENVHLTH-01: “Towards a better understanding and anticipation of the impacts of climate change on health”, iii) HORIZON-HLTH-2027-01-ENVHLTH-02: “Integrating climate-related exposures into the human exposome and characterising its changes in response to climate change”, iv) HORIZON-HLTH-2027-01-ENVHLTH-MISSCLIMA-03: “Tools and technologies to support health adaptation to climate change”, v) HORIZON-HLTH-2026-01-ENVHLTH-04: “Towards climate resilient, prepared and carbon neutral populations and healthcare systems”, vi) HORIZON-HLTH-2026-01-ENVHLTH-05: “Support for a multilateral initiative on climate change and health research”, vii) HORIZON-HLTH-2027-02-DISEASE-01-two-stage: “Innovative healthcare interventions for non-communicable diseases”, viii) HORIZON-HLTH-2026-02-DISEASE-12: “European Partnership on Rare Diseases (ERDERA) (Phase 2)”, ix) HORIZON-HLTH-2026-03-DISEASE-13: “European Partnership for Pandemic Preparedness (Phase 2)”, x) HORIZON-HLTH-2027-02-DISEASE-14-two-stage: “Clinical trials for advancing innovative interventions for neurodegenerative diseases”, xi) HORIZON-HLTH-2026-01-CARE-01: “Public procurement of innovative solutions for improving citizens' access to healthcare through integrated or personalised approaches”, xii) HORIZON-HLTH-2026-01-TOOL-03: “Integrating New Approach Methodologies (NAMs) to advance biomedical research and regulatory testing”, xiii) HORIZON-HLTH-2026-01-TOOL-05: “Pilot actions for follow-on funding: Leveraging EU-funded collaborative research in regenerative medicine”, xiv) HORIZON-HLTH-2026-01-TOOL-06: “Support to European Research Area (ERA) action on accelerating New Approach Methodologies (NAMs) to advance biomedical research and testing of medicinal products and medical devices”, xv) HORIZON-HLTH-2026-01-TOOL-07: “Establishing a European network of Centres of Excellence (CoEs) for Advanced Therapies Medicinal Products (ATMPs)” and xvi) HORIZON-HLTH-2025-02-DISEASE-01: “European Partnership for Brain Health”.

In addition to the priorities listed above, the Health Cluster will also continue to address the needs of specific populations, such as persons with disabilities and their families, with a focus on their empowerment. This is a crucial step towards ensuring that persons with disabilities can live independently and participate fully in society. Empowerment is also key for behavioural interventions, which this Work Programme part supports, by inviting proposals for the development of behavioural interventions as primary prevention for non-communicable diseases, to empower young people to adopt healthy lifestyles and reduce their risk of developing these diseases later in life.

Mental health remains a priority, with topics focusing on developing interventions to address the impact of climate change on mental health, as well as promoting healthy lifestyles and preventing mental health disorders. This includes a focus on the mental health of children and young adults, who are particularly vulnerable to the negative effects of digital technologies. The development of innovative interventions to prevent the harmful effects of using digital technologies on the mental health of children and young adults, in a gender sensitive way is a key objective, in line with the Commission's Political Guidelines for 2024-2029, which call for "protecting the mental health of our children and young people" in an increasingly digitalised world.

The Health Cluster will leverage public procurement to drive innovation, with two actions: a Pre-commercial Procurement (PCP) action on climate-resilient healthcare and a public procurement of innovative solutions action on integrated care, both aimed at improving healthcare outcomes.

This Work Programme part also supports the second phase of the co-funded European Partnership on Rare Diseases 10 and the co-funded European Partnership for Pandemic Preparedness 11 , providing continued funding to build on the progress achieved in the first phase and to further address the significant research, medical and societal challenges posed by rare diseases and pandemics.

It further identifies one action in support of STEP 12 objectives, for which proposals meeting the minimum requirements indicated in the specific call conditions will receive a STEP seal 13 (See topic HORIZON-HLTH-2026-01-TOOL-07: “Establishing a European network of Centres of Excellence (CoEs) for Advanced Therapies Medicinal Products (ATMPs)”).

Realising the potential of new Research and Innovation for society, requires close collaboration between research teams and prospective users of the knowledge and technology developed is paramount. It is therefore essential to involve these users -such as patients, healthy citizens, healthcare professionals, providers and payers, public health authorities, regulators, and innovators from academia and industry- early in the process of knowledge generation and technology development. This involvement can take the form of patient and citizen engagement, community involvement, and other social innovation approaches, ensuring that Research and Innovation activities align with the specific expectations, needs, constraints, and potential of users. Furthermore, effective intellectual property management strategies are crucial to maximise the benefits of such cooperation.

It is in the EU’s strategic interest to cooperate with countries beyond the EU, particularly for multilateral cooperation on (global) health issues. This includes countries associated to Horizon Europe as well as other partner countries and regions worldwide. In line with the EU’s Global Approach to Research and Innovation 14 , participation in the Health Cluster of Horizon Europe is open to third countries. Supporting the Global Gateway Strategy 15 , projects involving international partners should aim to increase scientific knowledge and facilitate technology transfer among partner countries, addressing global health challenges and fostering sustainable growth and job creation. Such cooperation should be value-based, creating linkages rather than dependencies. Please note that eligibility to participate is also subject to the ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility condition (see Annex B of the General Annexes of this Work Programme).

Applicants are encouraged to explore opportunities for synergies between the Health Cluster and other EU programmes 16 to enhance the reach and impact of their projects, such as through broader stakeholder cooperation and follow-on activities. Synergies are in particular foreseen between the Health Cluster and the EU4Health Programme (2021-2027) 17 to facilitate the uptake, further development and deployment of new knowledge and technologies in fields such as cancer, non-communicable diseases, mental health, pandemic preparedness and antimicrobial resistance, health systems and digital health. Synergies are also foreseen between the Health Cluster and the Digital Europe Programme 18 to leverage Horizon Europe Research and Innovation results, such as deploying digital, privacy-preserving (distributed) data infrastructures, high-performance computing resources, and developing methods and tools for modelling complex phenomena related to human health.

The European Regional Development Fund (ERDF) -including Interreg- focuses, amongst others, on the development and strengthening of regional and local Research and Innovation ecosystems and smart economic transformation, in line with regional/national smart specialisation strategies. The programme can for example support investment in research infrastructure, activities for applied Research and Innovation, including industrial research, experimental development and feasibility studies, building on Research and Innovation stemming from Horizon Europe 19 .

To further strengthen the impact of Research and Innovation efforts, Horizon Europe applicants could consider tapping into complementary activities offered by other relevant initiatives funded under the Horizon Europe programme. These include the innovation ecosystems and service provisions of the Knowledge and Innovation Communities (KICs) of the European Institute of Innovation and Technology (EIT), particularly EIT-KIC Health and EIT-KIC Digital, or the interregional networks funded under the European Innovation Ecosystems (EIE) component of Pillar III.

In addition, applicants to the Health Cluster are encouraged to explore opportunities for complementary topics and activities in other Clusters or parts of the Horizon Europe programme that address thematically similar challenges and areas of intervention. This can be in the Clusters of Pillar II, in the European Research Infrastructures Work Programme part (Pillar I), or in the European Innovation Council Work Programme (Pillar III). More specifically, beneficiaries of Horizon Europe grants are invited to consider possible collaborations and cross-fertilisation between their project and other projects selected under the same or other relevant calls.

For topics in this Cluster, consortia could consider voluntarily contributing data, indicators, and knowledge to relevant platforms of the European Commission's Joint Research Centre (JRC) and, where relevant, exchanging data and access with the decentralised EU agencies. This would help capitalise on the knowledge developed in their projects and enhance their relevance to policymaking 20 21 22 23 24 25 .

In the context of the Health Cluster Work Programme part for 2026-2027, FAIR data are data which meet the principles of findability, accessibility, interoperability, and reusability. Data may include, amongst others, exploitation of information, digital research data generated in the action, data from European research infrastructures and programmes such as Copernicus, European Space Agency and the GEO initiative. For further details, see the FAIR principles website 26 , the FAIR cookbook 27 and the guides for researchers on how to make your data FAIR 28 .

Applicants to calls of the Health Cluster are encouraged to consider, where relevant, the services offered by current and future EU-funded European Research Infrastructures, including those prioritised by the European Strategy Forum on Research Infrastructures (ESFRI) 29 , European Research Infrastructure Consortia (ERICs) 30 and the European Open Science Cloud 31 . Moreover, if projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, they must make use of European space technologies and services provided by Copernicus and/or Galileo/EGNOS (other data and services may additionally be used) 32 .

In the context of the Health Cluster Work Programme part for 2026-2027, a clinical study covers clinical studies/trials/investigations/cohorts and is defined as any systematic prospective or retrospective collection and analysis of health data obtained from individual patients or healthy persons in order to address scientific questions related to the understanding, prevention, diagnosis, monitoring or treatment of a disease, mental illness, or physical condition. It includes but it is not limited to clinical studies as defined by Regulation 536/2014 (on medicinal products), clinical investigation and clinical evaluation as defined by Regulation 2017/745 (on medical devices), performance study and performance evaluation as defined by Regulation 2017/746 (on in-vitro diagnostic medical devices).

Please note that the European Union (EU) pharmaceutical legislation known as the Clinical Trials Regulation No 536/2014 33 entered into application on 31 January 2022, repealing the Clinical Trials Directive (EC) No. 2001/20/EC and national implementing legislation in the EU Member States, which regulated clinical trials in the EU until the Regulation's entry into application. As a result, from 31 January 2023, all initial clinical trial applications in the European Union (EU) must be submitted via the Clinical Trials Information System (CTIS) 34 . CTIS is now the single-entry point for sponsors and regulators of clinical trials for the submission and assessment of clinical trial data.

The Horizon Europe strategic plan (2025-2027) sets out three Key Strategic Orientations (KSOs) for the last three years of the EU’s Framework Programme for Research and Innovation, namely: KSO 1: “The Green Transition,” aiming to support Europe in becoming the world’s first climate-neutral continent by 2050, tackling biodiversity loss and pollution; KSO 2: “The Digital Transition,” focusing on reinforcing Europe's competitiveness and strategic autonomy through research in core digital technologies; and KSO 3: “A More Resilient, Competitive, Inclusive, and Democratic Europe,” aiming to bolster Europe's social rights and democratic values, ensuring they are globally promoted. This includes research in civil security, health and wellbeing, a fair economic model, and democratic participation.

The Health Cluster will support these KSOs by enhancing the understanding of climate change impacts on health, developing tools to protect against global health challenges, and reducing the sector’s carbon footprint. It will promote technological and digital advancements to improve healthcare systems, focusing on disease prevention, personalised treatment, and equitable access to health services. Additionally, it will foster inclusive and resilient healthcare systems capable of responding to cross-border health threats and demographic changes, leveraging digital technologies such as AI to accelerate health research and improve health outcomes.

More specifically, the Health Cluster will support the KSOs by contributing to the six expected impacts set out for the Health Cluster in the strategic plan 2025-2027, which translate into the following six destinations of the Health Cluster Work Programme part for 2026-2027:

Destination “Staying healthy in a rapidly changing society”: The expected impact is that people of all ages in the EU stay healthy, resilient, and independent even as society changes fast. This will arise from healthier lifestyles and behaviour, healthier diets, healthier environments, improved evidence-informed health policies, and more effective solutions for health and wellbeing promotion, disease prevention and monitoring, and rehabilitation.

Destination “Living and working in a health-promoting environment”: The expected impact is that people's living and working environments are health-promoting and sustainable thanks to a better understanding of the environmental, occupational, social, sex and gender-related, and economic determinants of health.

Destination “Tackling diseases and reducing disease burden”: The expected impact is that healthcare providers improve their ability to tackle and manage diseases (infectious diseases, including poverty-related and neglected diseases, non-communicable and rare diseases) thereby reducing the disease burden on patients and enabling healthcare systems to perform more effectively. It can be achieved through better understanding, prevention, diagnostics, treatment, management, and cure of diseases and their co- and multi-morbidities, more effective and innovative health technologies and medical countermeasures, better ability and preparedness to manage pandemic and/or epidemic outbreaks, and improved patient safety.

Destination “Ensuring equal access to innovative, sustainable, and high-quality healthcare”: The expected impact is that healthcare systems provide equal access to innovative, sustainable and high-quality healthcare thanks to the development and uptake of safe, cost-effective and people-centred solutions. This is to be accompanied by management models focusing on population health, health systems resilience, and health equity and patient safety, and also improved evidence-informed health policies.

Destination “Developing and using new tools, technologies and digital solutions for a healthy society”: The expected impact is that health technologies, data, new tools, and digital solutions are applied effectively thanks to their inclusive, ethically sound, secure and sustainable delivery, integration and deployment in health policies and in health and care systems.

Destination “Maintaining an innovative, sustainable, and competitive EU health industry”: The expected impact is that the EU health industry is innovative, sustainable, and globally competitive thanks to improved uptake of breakthrough technologies and innovations (including social innovations) that make the EU with its Member States and Associated Countries more resilient and less reliant on imports of critical health technologies.

Calls

Call - Cluster 1 - Health (Single stage - 2026)

HORIZON-HLTH-2026-01

Overview of this call 35

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 36

Indicative number of projects expected to be funded

2026

Opening: 10 Feb 2026

Deadline(s): 16 Apr 2026

Destination - Staying healthy in a rapidly changing society

HORIZON-HLTH-2026-01-STAYHLTH-02: Behavioural interventions as primary prevention for Non-Communicable Diseases (NCDs) among young people

RIA

20.60

9.00 to 10.00

2

HORIZON-HLTH-2026-01-STAYHLTH-03: Building public trust and outreach in the life sciences

CSA

1.90

1.50 to 1.90

1

Destination - Living and working in a health-promoting environment

HORIZON-HLTH-2026-01-ENVHLTH-01: Towards a better understanding and anticipation of the impacts of climate change on health

RIA

55.00

7.00 to 8.00

7

HORIZON-HLTH-2026-01-ENVHLTH-04: Towards climate resilient, prepared and carbon neutral populations and healthcare systems

RIA

45.00

7.00 to 8.00

6

HORIZON-HLTH-2026-01-ENVHLTH-05: Support for a multilateral initiative on climate change and health research

CSA

3.00

Around 3.00

1

Destination - Tackling diseases and reducing disease burden

HORIZON-HLTH-2026-01-DISEASE-02: Innovative interventions to prevent the harmful effects of using digital technologies on the mental health of children and young adults

RIA

44.20

Around 8.00

6

HORIZON-HLTH-2026-01-DISEASE-03: Advancing research on the prevention, diagnosis, and management of post-infection long-term conditions

RIA

39.30

6.00 to 8.00

5

HORIZON-HLTH-2026-01-DISEASE-04: Development of novel vaccines for viral pathogens with epidemic potential

RIA

44.20

9.00 to 11.00

5

HORIZON-HLTH-2026-01-DISEASE-09: Multisectoral approach to tackle chronic non-communicable diseases: implementation research maximising collaboration and coordination with sectors and in settings beyond the healthcare system (GACD)

RIA

9.80

3.00 to 4.00

3

HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways

RIA

39.30

6.00 to 7.00

6

HORIZON-HLTH-2026-01-DISEASE-15: Scaling up innovation in cardiovascular health

CSA

1.90

Around 1.90

1

Destination - Ensuring equal access to innovative, sustainable, and high-quality healthcare

HORIZON-HLTH-2026-01-CARE-01: Public procurement of innovative solutions for improving citizens' access to healthcare through integrated or personalised approaches

PPI

24.50

3.00 to 8.00

4

HORIZON-HLTH-2026-01-CARE-03: Identifying and addressing low-value care in health and care systems

RIA

38.00

Around 10.00

4

Destination - Developing and using new tools, technologies and digital solutions for a healthy society

HORIZON-HLTH-2026-01-TOOL-03: Integrating New Approach Methodologies (NAMs) to advance biomedical research and regulatory testing

RIA

49.00

5.00 to 8.00

7

HORIZON-HLTH-2026-01-TOOL-05: Pilot actions for follow-on funding: Leveraging EU-funded collaborative research in regenerative medicine

IA

29.50

6.00 to 8.00

4

HORIZON-HLTH-2026-01-TOOL-06: Support to European Research Area (ERA) action on accelerating New Approach Methodologies (NAMs) to advance biomedical research and testing of medicinal products and medical devices

CSA

2.90

Around 2.90

1

HORIZON-HLTH-2026-01-TOOL-07: Establishing a European network of Centres of Excellence (CoEs) for Advanced Therapies Medicinal Products (ATMPs)

CSA

3.90

Around 3.90

1

Destination - Maintaining an innovative, sustainable, and competitive EU health industry

HORIZON-HLTH-2026-01-IND-03: Regulatory science to support translational development of patient-centred health technologies

RIA

19.60

4.00 to 6.00

4

Overall indicative budget

471.60

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Partnerships in Health (2026/1)

HORIZON-HLTH-2026-02

Overview of this call 37

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 38

Indicative number of projects expected to be funded

2026

2027

Opening: 10 Feb 2026

Deadline(s): 15 Sep 2026

Destination - Tackling diseases and reducing disease burden

HORIZON-HLTH-2026-02-DISEASE-12: European Partnership on Rare Diseases (ERDERA) (Phase 2)

COFUND

48.70

42.60

Around 91.30

1

Overall indicative budget

48.70

42.60

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Partnerships in Health (2026/2)

HORIZON-HLTH-2026-03

Overview of this call 39

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 40

Indicative number of projects expected to be funded

2026

2027

Opening: 10 Feb 2027

Deadline(s): 13 Apr 2027

Destination - Tackling diseases and reducing disease burden

HORIZON-HLTH-2026-03-DISEASE-13: European Partnership for Pandemic Preparedness (Phase 2)

COFUND

30.00

33.00

Around 63.00

1

Overall indicative budget

30.00

33.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Partnerships in Health (2026/3)

HORIZON-HLTH-2026-04

Overview of this call 41

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 42

Indicative number of projects expected to be funded

2026

Opening: 10 Feb 2026

Deadline(s): 16 Apr 2026

Destination - Ensuring equal access to innovative, sustainable, and high-quality healthcare

HORIZON-HLTH-2026-04-CARE-04: Enhancing and enlarging the European Partnership on Personalised Medicine (EP PerMEd) (Top-up)

COFUND

9.80

Around 9.80

1

Overall indicative budget

9.80

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Cluster 1 - Health (Single stage - 2027/1)

HORIZON-HLTH-2027-01

Overview of this call 43

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 44

Indicative number of projects expected to be funded

2027

Opening: 10 Feb 2027

Deadline(s): 13 Apr 2027

Destination - Staying healthy in a rapidly changing society

HORIZON-HLTH-2027-01-STAYHLTH-01: Addressing disabilities through the life course to support independent living and inclusion

RIA

39.30

6.00 to 8.00

5

Destination - Living and working in a health-promoting environment

HORIZON-HLTH-2027-01-ENVHLTH-02: Integrating climate-related exposures into the human exposome and characterising its changes in response to climate change

RIA

45.00

10.00 to 11.00

4

HORIZON-HLTH-2027-01-ENVHLTH-MISSCLIMA-03: Tools and technologies to support health adaptation to climate change

PCP

20.00 45

4.00 to 5.00

4

Destination - Tackling diseases and reducing disease burden

HORIZON-HLTH-2027-01-DISEASE-05: Development of novel small molecule antiviral therapeutics for pathogens with epidemic potential

RIA

44.20

9.00 to 11.00

5

HORIZON-HLTH-2027-01-DISEASE-06: Development of monoclonal antibodies to prevent and treat infections from Flaviviruses

RIA

37.30

9.00 to 10.00

4

HORIZON-HLTH-2027-01-DISEASE-07: Development of monoclonal antibodies to prevent and treat infections from Filo-, Nairo-, Phenui-, Picorna- and Toga viruses

RIA

37.30

9.00 to 10.00

4

HORIZON-HLTH-2027-01-DISEASE-08: Development of innovative antimicrobials against pathogens resistant to antimicrobials

RIA

44.20

8.00 to 10.00

5

HORIZON-HLTH-2027-01-DISEASE-10: Prevention and management of chronic non-communicable diseases in children and young people (GACD)

RIA

11.80

3.00 to 4.00

3

Destination - Ensuring equal access to innovative, sustainable, and high-quality healthcare

HORIZON-HLTH-2027-01-CARE-02: Personalised approaches to reduce risks from Adverse Drug Reactions due to administration of multiple medications

RIA

38.00

8.00 to 10.00

4

Destination - Maintaining an innovative, sustainable, and competitive EU health industry

HORIZON-HLTH-2027-01-IND-01: Development of cell-free protein synthesis platforms for discovery and/or production of biologicals

RIA

24.50

6.00 to 8.00

4

Overall indicative budget

341.60

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Cluster 1 - Health (Two stage - 2027)

HORIZON-HLTH-2027-02-two-stage

Overview of this call 46

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 47

Indicative number of projects expected to be funded

2027

Opening: 10 Feb 2027

Deadline(s): 13 Apr 2027 (First Stage), 22 Sep 2027 (Second Stage)

Destination - Tackling diseases and reducing disease burden

HORIZON-HLTH-2027-02-DISEASE-01-two-stage: Innovative healthcare interventions for non-communicable diseases

RIA

63.80

7.00 to 8.00

8

HORIZON-HLTH-2027-02-DISEASE-14-two-stage: Clinical trials for advancing innovative interventions for neurodegenerative diseases

RIA

39.30

Around 10.00

4

Destination - Developing and using new tools, technologies and digital solutions for a healthy society

HORIZON-HLTH-2027-02-TOOL-01-two-stage: Development of predictive biomarkers of disease progression and treatment response by using AI methodologies for chronic non-communicable diseases

RIA

44.20

6.00 to 8.00

6

Destination - Maintaining an innovative, sustainable, and competitive EU health industry

HORIZON-HLTH-2027-02-IND-02-two-stage: Portable and versatile Point-of-care diagnostics

IA

39.30

5.00 to 7.00

6

Overall indicative budget

186.60

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Cluster 1 - Health (Single stage - 2027/2)

HORIZON-HLTH-2027-03

Overview of this call 48

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 49

Indicative number of projects expected to be funded

2027

Opening: 03 Jun 2027

Deadline(s): 22 Sep 2027

Destination - Developing and using new tools, technologies and digital solutions for a healthy society

HORIZON-HLTH-2027-03-TOOL-02: Advancing bio-printing of living cells for regenerative medicine

RIA

39.30

7.00 to 10.00

4

HORIZON-HLTH-2027-03-TOOL-04: Virtual Human Twins (VHTs) for integrated clinical decision support in prevention and diagnosis

RIA

39.30

10.00 to 12.00

4

HORIZON-HLTH-2027-03-TOOL-08: Towards Artificial General Intelligence (AGI) for healthcare

CSA

2.90

Around 2.90

1

Overall indicative budget

81.50

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Destinations

Destination - Staying healthy in a rapidly changing society

Topics under this destination are directed towards the Key Strategic Orientations "A more resilient, competitive, inclusive, and democratic Europe” and “The Digital transition” of Horizon Europe’s strategic plan 2025-2027 50 .

Research and Innovation supported under this destination should contribute to the following expected impact, set out in the strategic plan impact summary for the Health Cluster: “people of all ages in the EU stay healthy, resilient, and independent even as society changes fast. This will arise from healthier lifestyles and behaviour, healthier diets, healthier environments, improved evidence-informed health policies, and more effective solutions for health and well-being promotion, disease prevention and monitoring, and rehabilitation”.

People´s healthcare needs are different depending on their age, gender, stage of life, health status and socioeconomic background. In 2021, nearly 860,000 premature deaths across the EU 51 could have been prevented with effective primary prevention and other public health measures. In addition, an estimated 135 million people in Europe live with a disability 52 , highlighting the critical need for healthcare systems that are both accessible and adaptable. This number is expected to rise due to population ageing and the increasing prevalence of chronic conditions resulting from noncommunicable diseases and injuries. It is also important to consider disabilities arising from other causes, such as war-related injuries and Post-Traumatic Stress Disorder (PTSD), which add to the complexity and diversity of healthcare needs.

Aligning with the Commission's Political Guidelines for 2024-2029 53 , which call for stepping up work on preventive health, this destination aims to strengthen disease prevention and early detection, placing support and empowerment of individuals regarding their own health, well-being and living and working conditions at the core of future public health programmes.

Research and Innovation under this destination should help enhance the dialogue and coordination among stakeholders and policymakers, ensuring integration across different care settings for holistic health promotion and disease prevention. Funded activities should seek to leverage the wealth of data sources, including real-world health data and establish a European interconnected health data ecosystem to develop integrated and personalised health promotion and disease prevention strategies. These activities will benefit from and actively support and enrich emerging data resources such as the European Health Data Space (EHDS) 54 and European Open Science Cloud (EOSC) 55 , and contribute to the European care strategy 56 and the digital transformation of health and care in the EU 57 . Since Horizon Europe’s launch in 2021, this destination has addressed important issues such as obesity prevention, understanding health-to-disease transitions, life course approaches to physical and mental health, healthy ageing, digital health literacy, and Artificial Intelligence (AI) for chronic disease risk prediction.

In this Work Programme part, destination “Staying healthy in a rapidly changing society” will focus on: i) addressing disabilities through the life course to support independent living and inclusion, with an emphasis on empowering persons with disabilities and their families. This priority aligns with the EU Strategy for the Rights of Persons with Disabilities 2021-2030; and ii) developing behavioural interventions as primary prevention for Non-Communicable Diseases (NCDs), with an emphasis on promoting healthy habits and sustained behavioural change among youth. This priority aligns with the ‘Healthier together’ EU non-communicable diseases initiative.

To increase the impact of EU investments under Horizon Europe, the Commission encourages collaboration between EU-funded projects to foster synergies through networking, joint workshops, knowledge exchange, best practices, and joint communication activities. Synergies can be explored between projects funded under the same or different topics, Clusters or Pillars of Horizon Europe. This includes collaborations between projects funded under the Health Cluster and the 'Culture, Creativity and Inclusive Society' Cluster for complementary actions, such as promoting social inclusion, health equity (including gender equality and support for groups at risk of discrimination), and mental health initiatives in education, work, and daily life (including through culture, the arts and sports).

Expected impacts:

Proposals for topics under this destination should set out a credible pathway to contributing to staying healthy in a rapidly changing society, and more specifically to one or several of the following impacts:

1.Citizens, including persons with disabilities and other groups in a vulnerable situation, adopt and maintain healthier lifestyles and behaviours, make healthier choices, and achieve, where applicable, longer healthy, independent, and active lives with a reduced burden of preventable disease throughout the life course.

2.Citizens are empowered to effectively manage their physical and mental health and well-being, monitor their health status, and interact with healthcare providers to optimise their well-being throughout life through improved health literacy, increased engagement in and adherence to health promotion strategies.

3.Children and young people are aware and empowered to better monitor and manage their physical, social and mental health with a view to lifelong healthy lifestyles.

4.Society benefits from reduced economic and health burdens due to preventable illness and premature mortality, with efficiency increased by targeting scarce resources in appropriate, cost-effective ways to areas of high social return, thereby driving improvements in health and well-being for all citizens, and specifically reducing health inequalities.

Health policies and actions for health promotion and disease prevention are knowledge-based, people-centred, personalised and thus targeted and tailored to citizens’ needs, and designed to reduce health inequalities.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in the Annex B of the General Annexes of this Work Programme.

The protection of European communication networks has been identified as an important security interest of the Union and its Member States. Entities that are assessed as high-risk suppliers 58 of mobile network communication equipment (and any entities they own or control) are not eligible to participate as beneficiaries, affiliated entities and associated partners to topics identified as “subject to restrictions for the protection of European communication networks”. Please refer to the Annex B of the General Annexes of this Work Programme for further details.

Proposals are invited against the following topic(s):

HORIZON-HLTH-2026-01-STAYHLTH-02: Behavioural interventions as primary prevention for Non-Communicable Diseases (NCDs) among young people

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 9.00 and 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 20.60 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Staying healthy in a rapidly changing society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to most of the following expected outcomes:

1.Healthcare professionals have access to behavioural interventions that can be used to establish and reinforce healthy habits and sustain behavioural changes.

2.Health professionals and educators have access to evidence-based strategies to mitigate risks of Non-Communicable Diseases (NCDs) for youth, with clear metrics that can be used to assess health outcomes.

3.Youth have increased individual responsibility through targeted education, digital services, including easily accessible tools for self-monitoring, and community-based support, stemming from increased collaboration between healthcare professionals, educators and families.

4.Researchers have access to Real-World Data (RWD) 59 , existing health data infrastructure and digital tools, including Artificial Intelligence (AI), which can contribute to the sustained success of behavioural health interventions.

5.Policymakers at local, regional, national and EU levels have new knowledge on behavioural interventions on NCDs among youth, which they can use to improve interventions in diverse European contexts.

Scope: The topic is focused on behavioural interventions for youth, defined as 12 to 25 years old, for the primary prevention of the top NCDs later in life, where “top NCDs” refers to the most prevalent NCDs 60 . For the purpose of this call, NCDs explicitly exclude cancer.

Implementation research should be conducted to implement existing behavioural interventions. These interventions should be evidence-based and have an emphasis on empowerment and self-management (e.g. health literacy, health education, health promotion). As self-monitoring is an essential element of self-management, proposals should include user-friendly hardware and software for efficient self-monitoring (i.e. wearables and point-of-care devices for measuring various physiological parameters and other predictors and other biomarkers and the corresponding apps for easy readout and tracking, possibly also including gamification elements). Hardware and software should be interoperable in line with internationally accepted standards in order to avoid lock-in effects and assure scalability.

Proposals should also include most of the following aspects:

1.Ensure that gender-sensitive and intersectional approaches are integrated, addressing potential gender-specific barriers for groups at risk of discrimination, as well as cultural and socioeconomic backgrounds, and should also outline how digital tools, including AI and RWD and biomarkers (e.g. genomic data, wearables, etc.) or existing relevant administrative dataset, will be integrated to enhance the scalability, personalisation, and effectiveness of interventions in the long-term.

2.Present a clear, evidence-based strategy showing how the interventions will be tailored, deployed, and assessed at individual, family, community, and societal levels, while considering social inequalities and lifestyle factors (i.e. nutrition, sleep rhythm) and ensuring a robust methodological framework for evaluating the effectiveness of interventions (e.g. randomised controlled trails, quasi-experimental designs, etc.), with clearly defined indicators of success of the intervention (e.g. biometric markers, psychosocial wellbeing metrics, physical activity change, etc.). Applicants should evaluate unintended consequences for all interventions.

3.Include formats that will increase collaboration between healthcare professionals, educators, families, and policymakers in promoting preventive health and should include plans for longer-term follow-up to estimate health impact and cost savings over time. Related to this, applicants should outline how policy changes related to the intervention (e.g. school meal programmes, safe urban infrastructure for exercise, digital literacy campaigns, circadian alignment, stress reduction strategies) can reinforce and scale up successful behavioural interventions, whilst taking into account how they can be replicated or adapted to different cultural, geographic and socio-economic contexts. As such, active involvement of key stakeholders throughout the study is strongly encouraged.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, organisations as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

The proposals should adhere to the FAIR 61 data principles, adopt data quality standards, data integration operating procedures and GDPR 62 compliant data sharing/access good practices developed by the European research infrastructures, where relevant.

Applicants should provide details of their clinical studies 63 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2026-01-STAYHLTH-03: Building public trust and outreach in the life sciences

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 1.50 and 1.90 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 1.90 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, legal entities established in the United States of America may exceptionally participate as a beneficiary or affiliated entity, and are eligible to receive Union funding.

Coordinators of projects must be legal entities established in an EU Member State or Associated Country.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 64 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Staying healthy in a rapidly changing society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Strengthened capacity of life sciences actors in science communication, risk communication, public outreach, and citizen engagement.

2.Strengthened awareness of risks and benefits of life sciences by the public, by showcasing the latest Research and Innovation (R&I) developments in the life sciences, and their societal impact.

3.New and innovative approaches developed to engage the public in R&I activities in the life sciences, with an emphasis on inclusive and participatory approaches, involving relevant stakeholders (e.g. researchers, research funders, policymakers, publishers, civil society organisations, business, and citizens).

Scope: Life science innovations significantly contribute to peoples’ daily life and to individual and social well-being. To foster public trust, people must understand how life sciences work and how these technologies may impact people’s lives.

This trust is not guaranteed. It is increasingly threatened by the rapid spread of mis- and disinformation and by insufficient outreach to and involvement of people to address their concerns and expectations. To maintain and deepen trust, especially among young people, R&I policymakers, researchers and industry players must be better equipped to engage with the public and to pursue responsible research and innovation.

Citizen engagement is particularly critical in areas like agriculture and food technology, where innovation intersects with health and sustainability considerations and values. Furthermore, citizen participation is key to build trust in the life sciences and ensure that they meet societal needs. By engaging citizens early on, we can ensure that research and innovation align with their values, concerns and expectations. This involves designing research and innovation processes that incorporate citizen input, such as setting research priorities, and create outcomes that are responsive to their needs.

To this end, proposals should address all the following activities:

1.Provide advisory support and training to life science stakeholders, in order to upskill them in science communication and risk communication.

2.Produce, publish and advertise to the relevant actors, guidance to engage citizens upstream in the development, co-production, and co-design of life sciences innovation.

3.Produce, publish, and advertise to the relevant public an accessible repository of tools for life science stakeholders on risk communication.

4.Design and run community engagement activities in the life sciences, in partnership with relevant local actors, such as science museums, R&I organisations, and/or community organisations.

Regarding advisory support and training, proposals should present how they will engage bilaterally with life science stakeholders to advise them and train them on science communication and risk communication in the life sciences. The proposal selected for funding should also establish links with the European Competence Centre for Science Communication 65 currently being created by the COALESCE 66 project and expected to be launched in 2027 67 .

Regarding engagement of citizens in the development, co-production and co-design of life sciences innovations, proposals should focus on advising and training life science actors in deliberative citizen participation and co-design with citizens, including tools that allow discussions about values and ethical considerations of innovations in this sector. Proposals should set out the ways in which they will support life science actors to involve citizens in co-design, and also set out how they will evaluate the impact of the citizen engagement activities that they have supported. The consortium selected for funding is encouraged to use the tools and methods developed under previous research and tailor them to the life sciences.

Regarding the repository of tools and support for risk communication, such tools already exist and have been developed, notably the EU funded projects listed in the CORDIS Results Pack “Science communication: Empowering citizens in the public discussion of science” 68 , the CORDIS Results Pack “Ethics and integrity: Building bridges for trust and excellence in research and innovation” 69 and the World Health Organization (WHO) guidelines for emergency risk communication 70 . Proposals should present what tools they will gather, how they will publish them, and what publicity and outreach they will conduct to raise awareness of this repository among the relevant life science actors (policymakers, researchers, industry, civil society organisations), tailoring tools and trainings to the life sciences. Proposals should present a long-term strategy for how the repository of tools will continue to be accessible beyond the lifecycle of this Coordination and Support Action (CSA).

Regarding community engagement activities, proposals should experiment with new and engaging formats across the programmed activities. Proposals should promote both science education, and multiple forms of public engagement with science, focusing on the life sciences. Proposals should focus on any areas within the life sciences, but at least one community engagement activity should focus on agriculture and food technology. The consortium selected for funding is encouraged to make use of findings and tools for stakeholder engagement developed by other Horizon Europe projects, including projects funded under topic HORIZON-CL6-2023-GOVERNANCE-01-6: “Co-creation and trust-building measures for biotechnology and bio-based innovation systems”. The consortium selected for funding is also encouraged to establish links with the projects funded under topic HORIZON-WIDERA-2026-07-ERA-05: “Pillar III: Fostering citizen engagement for more responsible and democratic R&I”, that will develop tools and guidelines on public engagement in R&I, and to tailor these tools and guidelines to applications in the life sciences. Proposals should explain how they will partner with relevant local actors, such as science museums, R&I organisations, and/or community organisations, to run innovative community engagement activities on the life sciences.

Proposals may consider involving the European Commission's Joint Research Centre (JRC) to participate in the advisory board of the consortium selected for funding, notably to benefit from the expertise of the JRC's Competence Centre on Participatory and Deliberative Democracy 71 , regarding the engagement of citizens in the design of life sciences innovations and community engagement activities. Any such collaboration should be established after the proposal’s approval.

HORIZON-HLTH-2027-01-STAYHLTH-01: Addressing disabilities through the life course to support independent living and inclusion

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 39.30 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 72 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Staying healthy in a rapidly changing society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Persons with disabilities are empowered and can enjoy their rights to live independently, participate in society and be included in the community on an equal basis with others.

2.The scientific community develops innovative solutions with a focus on removing barriers faced by persons with disabilities to live independently and they are provided with community support services where they live in the community.

3.Policymakers, health and care services, social and service providers, disability organisations, funders, the scientific community, and other relevant bodies are informed of the research advances and best practices addressing the health and needs of persons with disabilities to support them living independently and being included in society.

Scope: The focus of this topic is human-centred on persons with long-term disabilities 73 -physical, mental, intellectual or sensory- aiming at supporting independent living across the life-course from a health perspective. Persons with disabilities have an equal right to live independently and be included in the community. Independent living requires a differentiated landscape of quality, accessible, person-centred and affordable, community- and family-based services comprising personal assistance, medical and social care and interventions by social workers, thereby facilitating everyday activities and providing choice to persons with disabilities and their families 74 .

The objective of this topic is to explore new ways to promote independent living and inclusion in society of persons with disabilities, reducing to the maximum possible the impact of barriers faced in their daily lives, and supporting the transition from institutions to living in the community while addressing all-encompassing aspects of personal support, such as community transformation, service provision, assistive and accessible technologies and environments.

Research actions under this topic should address at least three of the following areas:

1.Health related research addressing disabilities that stem from health conditions and health conditions associated to disabilities. Thus, research may look into finding the causes of the disease(s) leading to the disability and/or disease treatment with the purpose of supporting independent living. Innovative solutions could also include among others diagnoses, medicines, treatments, protocols, technologies, digital tools, low-tech solutions, etc. helping to improve the autonomy of persons with disabilities.

2.Children with disabilities from the perinatal period, and/or young people with disabilities transitioning to adulthood, and/or older persons 75 . Proposals should foster ways to improve autonomy and quality of life.

3.Access to habilitation and rehabilitation services, including psychological rehabilitation and innovative rehabilitation with assistive technologies when appropriate, to increase, maintain, substitute or improve functional capabilities of persons with disabilities or for, alleviation and compensation of impairments, activity limitations or participation restrictions contributing to increasing independence.

4.Prevention of disabilities through the life-course. Different aspects that could have an impact on persons with disabilities may be addressed, such as gender, age, socio-economic background, ethnicity, detection of risks factors leading to a loss of autonomy, the risk of overweight/obesity and related co-morbidities (e.g. diabetes, cardiovascular diseases), hospitalisation, nutrition (e.g. mother and child nutrition from pregnancy), high level of inactivity/sedentary lifestyle and related co-morbidities (e.g. frailty), physical activity/sports, screen-time dependency, smoking, drug use 76 , alcohol use, stress, psychiatric and somatic diseases, loneliness and/or isolation, etc.

5.Conditions for a successful transition from institutions to living in the community, including different tools to achieve it, such as needs assessments, service provision, budget and resources, management plans, monitoring, quality control, etc. Community support services to live independently may include personal assistance or support for decision-making, and/or disability inclusive and accessible community-based services -medical, technological, digital or other supportive initiatives- ensuring prevention of isolation or segregation and supporting deinstitutionalisation. Special attention is to be paid to children and young people transitioning to adulthood and older persons to facilitate they remain living at their homes 77 .

6.Innovative solutions, care models and strategies for high quality person-centred, accessible and targeted social and healthcare services to prevent barriers and to support independent living, including if possible, self-care to empower persons with disabilities, as well as different choices of care across the life-course. For many persons with disabilities, the lack of support and care services and insufficient support for families and unavailability of personal assistance undermines their independence and inclusion in the community.

Data collection is essential to understand the living situation of persons with disabilities and remains a challenge to collect data disaggregated per type of disability, sex, and age. In addition, data collected often lacks comparability as it follows different definitions in each Member State and Associated Country. Thus, applicants are encouraged to ensure harmonised data collection by using Eurostat standards and existing international sets of questions in their areas of research.

Persons with disabilities should be involved in the research through their representative organisations as actors in the research process. Research can also involve their families, friends, colleagues, supporters and carers and other service providers. Policymakers and public authorities, social services, and civil society organisations, could also be considered.

The relevant European research infrastructures 78  in the area of health may be exploited for available digital tools and services for dataset creation, standardisation, data discovery, secure access, management, visualization, harmonization, analysis and other functions as appropriate.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, organisations as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

Projects are also encouraged to explore potential complementarities with projects funded under topic HORIZON-CL2-2025-01-TRANSFO-09: “Good practices for increased autonomy of persons with disabilities, including physical, mental, intellectual and sensory disabilities” and topic HORIZON-HLTH-2025-03-STAYHLTH-01-two-stage: “Improving the quality of life of persons with intellectual disabilities and their families”.

Applicants envisaging to include clinical studies 79 should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

Destination - Living and working in a health-promoting environment

Topics under this destination are directed towards the Key Strategic Orientation 1 “The Green transition” and Key Strategic Orientation 3 “A more resilient, competitive, inclusive, and democratic Europe” of Horizon Europe’s strategic plan 2025-2027 80 .

Research and innovation supported under this destination should contribute to the following expected impact, set out in the strategic plan impact summary for the Health Cluster: “people's living and working environments are health-promoting and sustainable thanks to a better understanding of the environmental, occupational, social, sex and gender-related, and economic determinants of health”.

The environment we live and work in is a major determinant of our health and wellbeing and climate change acts as a risk multiplier, exacerbating the health effects of environmental stressors, increasing the incidence of non-communicable diseases, mental health conditions, and infectious diseases, particularly for populations in a vulnerable situation. The climatic crisis is a health crisis with impacts at the global level. Across Europe, the fastest-warming continent, heat and floods have caused devastating human and economic impact in recent years. In 2025, the Commission published a Strategic Research and Innovation Agenda on Health and Climate Change 81 , providing a forward-looking overview of the current and emerging research needs and gaps in the field. This agenda informs the focus and objectives of this destination, aligning with the Commission's Political Guidelines for 2024-2029 82 , which emphasise the need to step up work on preventive health, climate resilience, adaptation, preparedness, and the green transition, while promoting circularity.

In this Work Programme part, Destination "Living and working in a health-promoting environment" focuses on understanding and addressing the impacts of climate change on human health, increasing climate adaptation and resilience and reducing the health sector's contribution to climate change. The results will support the EU Strategy on Adaptation to Climate change, the European Climate Adaptation Plan (thematic window on health) and the European Climate Risk Assessment by enhancing understanding of health risks and informing prevention, adaptation, and mitigation actions for populations and healthcare systems. Moreover, this destination aims to identify and amplify the co-benefits of climate action for health outcomes. This integrated approach recognises that climate mitigation measures can simultaneously deliver significant health benefits, creating positive feedback loops between climate protection and public health. Strong collaborations across sectors and with other Horizon Europe Clusters dealing with issues such as agriculture, fisheries and aquaculture, food, environment, climate, biodiversity, mobility, security, urban planning, social inclusion and gender will be needed to ensure that maximal societal benefits are reached. In view of increasing the impact of EU investments under Horizon Europe, the Commission welcomes and supports cooperation between EU-funded projects to enable cross-fertilisation and create synergies. This could range from networking to joint activities such as the participation in joint workshops, the exchange of knowledge, development and adoption of best practices, or joint communication activities. Unless specified otherwise, all topics are open to international collaboration to address global climate and health challenges.

Expected impacts:

Proposals for topics under this destination should set out a credible pathway to contributing to living and working in a health-promoting environment, and more specifically to one or several of the following impacts:

1.Policymakers and regulators are aware and well informed about climatic, environmental, socio-economic and occupational risk factors as well as health-promoting factors across society.

2.Climatic, environmental, occupational, social, economic, and health policies and practices at the EU, national and regional level are sustainable and based on solid scientific evidence.

3.The upstream determinants of health are known, understood and reduced.

4.The health threats and burden and patient safety burdens resulting from exposure to climate drivers are lessened, so that the related number of deaths and illnesses is substantially reduced.

5.Living and working environments in European cities and regions are healthier, more inclusive, safer, resilient and sustainable.

6.The healthcare sector reduces its environmental footprint and transitions towards carbon neutrality.

7.The adaptive capacity and resilience of populations and health systems in the EU to climate and environmental change-related to mental and physical health risks are strengthened.

8.Citizens’ health and wellbeing are protected and promoted, and premature deaths, diseases and inequalities related to climate related risks are prevented.

9.Citizens understand better complex climate, environment and health issues, and effective measures to address them and support related policies and regulations.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in the Annex B of the General Annexes of this Work Programme.

Proposals are invited against the following topic(s):

HORIZON-HLTH-2026-01-ENVHLTH-01: Towards a better understanding and anticipation of the impacts of climate change on health

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 7.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 55.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced project portfolio covering the broad focus areas targeted in this topic 83 , grants will be awarded (within available budget) to proposals not only in order of ranking but at least also to those proposals that are the highest ranked within different broad focus areas targeted, provided that the proposals attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

In order to maximise synergies and increase the impact of the projects, all proposals selected for funding from this topic will form a cluster and be required to participate in common networking and joint activities (and in determining modalities for their implementation and the specific responsibilities of projects). These activities will be included in a dedicated work package, having sufficient budget allocated to it (around 2% of the total requested budget). Depending on the scope of proposals selected for funding, these activities may include:

1.Attendance of regular joint meetings (e.g. common kick-off meeting and annual meetings).

2.Periodic report of joint activities (delivered at each reporting period).

3.Common dissemination and communication activities (which may include, for example: a common dissemination and communication strategy, web portal and visual identity, brochure, newsletters).

4.Common Data Management Strategy and Common Policy Strategy (including joint policy briefs).

5.Thematic workshops/trainings on issues of common interest.

6.Working groups on topics of common interest (e.g. data management and exchange, communication and dissemination, science-policy link, scientific synergies).

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 84 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Living and working in a health-promoting environment”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to most of the following expected outcomes:

1.Citizens, patients, public authorities, social care services, healthcare practitioners and policymakers have a better understanding of the climatic health risks and determinants of disease and are better equipped to address health outcomes through enhanced and inclusive prevention, resilience, adaptation, preparedness and response, including better diagnosis and treatment.

2.Governments, public health authorities, researchers and civil society organisations are supported to tackle societal challenges linked to the health impacts of climatic factors.

3.Public authorities, organisations and the research community can rely on data collection and sharing according to FAIR 85 principles and leveraging of data availability and quality.

4.Policymakers and public authorities develop evidence-based climate change and health policies and interventions that are nature positive, inclusive and responsive to diverse population needs.

Scope: The climate crisis poses an existential challenge to planetary and human health with larger effects on populations, groups and regions in a vulnerable situation. Climate change increases the incidence of non-communicable diseases and the prevalence of mental health conditions and facilitates the emergence and spread of infectious diseases. Climate change can act as a risk multiplier and exacerbates existing health conditions and vulnerabilities.

Applicants should explicitly state in their proposal which of the following broad focus areas is targeted and the proposed work should address only this specific broad focus area:

1.Non-Communicable Diseases (NCDs) and/or individual safety (e.g. injuries or fatalities), excluding mental health aspects: proposals should explore evidence on the complex interactions between climate change (e.g. changes in the frequency and intensity of extreme weather events) and NCDs and individual safety, which often involve multiple climate exposure pathways and compound and cascading climatic events.

2.Mental health, considering interactions with brain health if relevant: in the broad focus area of mental health and psychosocial well-being, proposals should increase the evidence on the acute and long-term impacts of climate change and the understanding of new syndromes related to climate stress.

3.Infectious diseases, including vector-borne and non-vector-borne: proposals should increase the understanding of the factors driving climate-related burden from infectious diseases.

In general, proposals should develop approaches to prevent and reduce the impacts of climate factors in the studied health outcomes and increase population and workforce resilience. A One Health approach should also be applied where relevant.

More specifically, research actions under this topic should include several of the following activities, depending on the relevance of each group of activities to the broad focus area targeted in the proposal:

1.Increase the understanding of correlations, causal pathways and mechanistic effects between climate change and disease/health outcomes, developing unified and standard methodologies and metrics to assess short- and long-term positive and negative impacts of climate change with an adequate level of granularity. Consider individual and/or cascading climatic events and exposure patterns, and risks and drivers of vulnerability and inequality.

2.Develop longitudinal studies to better ascertain differential effects of climatic stressors on health including multiple scales of impacts, ranging from the molecular level to population health outcomes. Consider variability across populations, generations and life phases, regions and occupations, and collect real-world exposure and health data in living and occupational settings, considering the use of emerging ecosystems such as the European Health Data Space (EHDS) 86 and the European Open Science Cloud (EOSC) 87 .

3.Study differential acute and long-term health impacts of climate (including a wide range of factors and cumulative effects) on vulnerable, sensitive or exposed population groups. Consider also differences in geographical vulnerabilities including, when relevant, geographical settings outside of urban areas, in overseas regions and in low- and middle-income countries (LMICs) 88 . Understand the role of inequalities and societal vulnerability in determining climate-related health impacts and adaptive capacity.

4.Advance the knowledge on the climate, ecological and environmental drivers of pathogen abundance, including mechanisms and determinants of distribution, life-cycle patterns, transmission, virulence and survival. Consider climate change drivers of disease severity. Study host/pathogen and vector/host interactions clarifying the role of secondary reservoir hosts such as sylvatic, wildlife and livestock in the maintenance of pathogen life cycle. Assess the efficacy, cost-effectiveness and impact of control measures.

5.Explore the role of climate-driven human and wildlife mobility (e.g. bird migration patterns, human migration) in enhancing the global spread of pathogens and creating opportunities for their local establishment. Collect better field data and develop tools for disease modelling, risk and scenario projections that encourage interoperable data systems and cross border collaboration.

6.Increase the availability, accessibility, quality and standardisation of diagnostic testing for early diagnosis of infections and determining immune responses and vaccine efficacy. Increase the capacity for pathogen subtyping, and genomic surveillance for early warning and investigations of climate-related outbreaks. Develop rapid, portable, and affordable standardised diagnostic tools that can withstand climate extremes.

7.Increase the understanding of the factors that strengthen health resilience to climate change at the individual, local and societal levels. Investigate the role of individual mechanisms, community resilience and local solutions in mitigating the health impacts of climate change and related environmental degradation.

International cooperation, in particular with LMICs, is strongly encouraged.

In order to maximise synergies and increase the impact of the projects, all proposals selected for funding from this topic will form a cluster and be required to participate in common networking and joint activities. Guidance on the potential activities to be developed can be obtained by consulting the clusters of projects ongoing under the Environment, Climate and Health research portfolio 89 .

Proposals should make sure that relevant activities, outcomes and outputs are shared with the European Climate and Health Observatory 90 through the cluster that will be formed after the approval of the proposals. Actions’ results should also contribute to future European Climate Risk Assessments. When relevant proposals should build on the outcomes of the projects that are part of the European Climate-Health Cluster 91 .

Proposals are encouraged to consider, where relevant, the data, expertise and services offered by European research infrastructures 92 in the environment, climate and health domain.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

Applicants envisaging to include clinical studies 93 should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

HORIZON-HLTH-2026-01-ENVHLTH-04: Towards climate resilient, prepared and carbon neutral populations and healthcare systems

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 7.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 45.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

In order to maximise synergies and increase the impact of the projects, all proposals selected for funding from this topic will form a cluster and be required to participate in common networking and joint activities (and in determining modalities for their implementation and the specific responsibilities of projects). These activities will be included in a dedicated work package, having sufficient budget allocated to it (around 2% of the total requested budget). Depending on the scope of proposals selected for funding, these activities may include:

1.Attendance of regular joint meetings (e.g. common kick-off meeting and annual meetings).

2.Periodic report of joint activities (delivered at each reporting period).

3.Common dissemination and communication activities (which may include, for example: a common dissemination and communication strategy, web portal and visual identity, brochure, newsletters).

4.Common Data Management Strategy and Common Policy Strategy (including joint policy briefs).

5.Thematic workshops/trainings on issues of common interest.

6.Working groups on topics of common interest (e.g. data management and exchange, communication and dissemination, science-policy link, scientific synergies).

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 94 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Living and working in a health-promoting environment”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to most of the following expected outcomes:

1.The healthcare sector is supported with new technological developments and frameworks for greening, decarbonising and adapting to climate change, thus also contributing to protect biodiversity and ecosystem services.

2.Governments, public health authorities, healthcare providers and practitioners, social care services and civil society have access to the best available evidence on the health costs and benefits (including co-benefits) of climate adaptation and mitigation actions and interventions.

3.Policymakers and public authorities develop environment, climate change and health policies and interventions based on robust frameworks and incorporating innovative, inclusive and accessible solutions and technologies.

4.Governments and public health authorities are supported in their adoption of robust frameworks and interventions to tackle societal challenges linked to the health impacts of climatic and environmental factors.

5.Populations are empowered and equipped with knowledge, tools and resources to adopt health-protective behaviours and adapt to health-related climate risks.

Scope: The health sector accounts for nearly 5% of global greenhouse gas (GHG) emissions and generates significant demands for energy and materials, as well as dangerous polluting streams. Proactive mitigation efforts in the health sector can significantly reduce GHG emissions and pollution, saving many lives and contributing to relieve pressures on biodiversity and ecosystem services. However, specific mechanisms for emission reductions in the health sector remain less defined compared to those in other sectors.

At the same time, the climate crisis subjects healthcare systems to unprecedented pressures (e.g. on infrastructure, workforce, overall systems) while simultaneously having to respond to increasing healthcare needs. To reduce pressure in healthcare systems and generally improve public health, it is crucial to design inclusive and accessible interventions that prevent the health impacts of climate change and related environmental degradation, increase resilience and preparedness of individuals and communities and foster the adoption of health-protective behaviours.

Research activities under this topic should generate evidence on the opportunities and health co-benefits of mitigation in the health sector as well as foster the development of low-carbon medical technologies and digital solutions for the sector. Proposals should also support the design of effective, scalable, cost-effective and transferable interventions and frameworks that can be applied across a wide range of healthcare settings and/or in population, community and societal contexts and involving, when relevant, public and patient engagement. Proposals can consider both living and working environments.

More specifically research actions under this topic should include some of the following activities:

1.Develop and/or pilot effective, inclusive, accessible and impactful interventions to address the impact of climate change in healthcare systems and/or in health outcomes across populations, sectors and regions. These interventions should aim at reducing health vulnerability and building health resilience. Consider where relevant the involvement of local communities and/or end users in the development of these interventions.

2.Develop methodologies and analytical tools to assess the effectiveness and cost-benefit of health-related climate change adaptation interventions.

3.Generate evidence on the health co-benefits of climate change mitigation and propose frameworks to quantify the magnitude of their impacts.

4.Develop harmonised frameworks, assessment metrics and reporting methods to evaluate alternative mitigation strategies and interventions, as well as harmonised methodologies to assess the cost-benefit of different mitigation measures.

5.Explore and estimate the impact of preventive healthcare and lifestyle practices for mitigating the impacts of climate change in the health sector and increasing the resilience and preparedness of communities.

6.Propose best practices to enhance the climate resilience of healthcare infrastructures, healthcare professionals and relevant supply chains and logistics.

7.Explore and assess the role of primary care in increasing the preparedness of communities and reduce the health impacts of climate change.

8.Develop low-carbon medical technologies (including medical devices) and digital solutions to reduce the emissions of GHG and pollutants (to air, water and soil) of healthcare practices and their supply chains. Health technology assessment activities to evaluate new or alternative low carbon medical solutions may be included where appropriate.

Funded projects under this topic should consider the scalability and transferability of the developed solutions to ensure that any knowledge, frameworks, methodologies, pilots, etc., developed are actionable and applicable across different healthcare settings and community contexts. Proposals should also consider the use of implementation science approaches to support the relevance and broad applicability of the research outcomes. Proposals should take into consideration the broader socio-economic challenges faced by healthcare systems (e.g. funding challenges, workforce shortages, population ageing and increase of chronic diseases). Additionally, solutions and interventions proposed under this topic should consider the Do No Significant Harm principle.

In order to maximise synergies and increase the impact of the projects, all proposals selected for funding from this topic will form a cluster and be required to participate in common networking and joint activities. Guidance on the potential activities to be developed can be obtained by consulting the clusters of projects ongoing under the Environment, Climate and Health research portfolio 95 .

International cooperation is encouraged.

Proposals should make sure that relevant activities, outcomes and outputs are shared with the European Climate and Health Observatory 96 through the cluster that will be formed after the approval of the proposals. When relevant proposals should build on the outcomes of the projects that are part of the European Climate-Health Cluster 97 .

Proposals are encouraged to consider, where relevant, the data, expertise and services offered by European research infrastructures 98 in the environment and health domain.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

Applicants envisaging to include clinical studies 99 should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

HORIZON-HLTH-2026-01-ENVHLTH-05: Support for a multilateral initiative on climate change and health research

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, legal entities established in the United States of America may exceptionally participate as a beneficiary or affiliated entity, and are eligible to receive Union funding.

Coordinators of projects must be legal entities established in an EU Member State or Associated Country.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 100 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Living and working in a health-promoting environment”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to most of the following expected outcomes:

1.An international multilateral initiative is established to facilitate coordination and synergy between different research and innovation funding organisations tackling climate change and health issues with adequate support of a secretariat that works towards the definition of a governance model and forward-looking plan for the implementation of this initiative.

2.The international community of research funders working in the climate-health nexus is well connected and supported to improve coordination of activities and alignment of priorities and increase the collective impact of funding streams.

3.The research community, civil society groups and policymakers working in the climate-health nexus are well informed about the initiative’s activities and benefit from the knowledge, tools and opportunities created during its implementation.

Scope: Climate-related health challenges are global and complex in nature, which calls for coordinated action bringing together different research disciplines, policy sectors, perspectives and approaches. This requires seamless communication and synergies between different Research and Innovation (R&I) funding instruments.

R&I is key to increasing our understanding of existing and emerging climate-related vulnerabilities experienced by populations and health systems alike, as well as to supporting the development and implementation of effective and sustainable interventions for prevention, adaptation and preparedness against climate-related health threats. They also play a crucial role in supporting the health sector’s transition towards decarbonisation and long-term sustainability while ensuring that quality of care is maintained or improved.

R&I funding schemes and programmes will structure and accelerate the health response needed to meet the severity of the climate crisis in the decades to come. Achieving this requires building on a truly collaborative and impactful network of key players that optimally and efficiently structure and align their research programmes and funding streams.

The Commission, in collaboration with other funders and international organisations, will work on the development of a collaborative interface that brings together research funders from around the world working at the intersection of health and climate. This platform will establish opportunities for participating organisations to discuss challenges and priorities and share best practices, research strategies and implementation plans. The platform will also serve to identify areas of common interest for collaboration and to build a shared vision to support health and climate research globally.

Proposals under this topic should focus on the provision of administrative and technical support to the successful establishment and implementation of a multilateral initiative of research and innovation funders working in climate change and health.

More specifically, proposals are expected to focus on all the following activities:

1.Build on the preparatory work done and further support exchanges between relevant parties to delineate the operational structure and governance model of the multilateral initiative, in close collaboration with the European Commission.

2.Facilitate and support the drafting of the workplan for the first period of activities of the multilateral initiative.

3.Provide administrative and organisational support to the board of the multilateral initiative, in close collaboration with the chairs of the initiative.

4.Provide scientific and technical support in aspects relevant to the development and implementation of the multilateral initiative.

5.Facilitate communication between members of the initiative as well as with external stakeholders and organisations, and support the organisation of necessary meetings and the preparation of supporting material.

6.Support external communication activities such as the creation of a website, newsletters, social media outreach and any other relevant communication and dissemination materials to promote the multilateral initiative.

HORIZON-HLTH-2027-01-ENVHLTH-02: Integrating climate-related exposures into the human exposome and characterising its changes in response to climate change

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 10.00 and 11.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 45.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries will be subject to the following additional dissemination obligations: Proposals should ensure that chemical monitoring and human biomonitoring data are shared in the Common Data Platform for Chemicals and its services such as the Information Platform for Chemical Monitoring - IPCHEM 101 (through involvement with the European Commission's Joint Research Centre - JRC) and the environmental sustainability database.

In order to maximise synergies and increase the impact of the projects, all proposals selected for funding from this topic will form a cluster and be required to participate in common networking and joint activities (and in determining modalities for their implementation and the specific responsibilities of projects). These activities will be included in a dedicated work package, having sufficient budget allocated to it (around 2% of the total requested budget). Depending on the scope of proposals selected for funding, these activities may include:

1.Attendance of regular joint meetings (e.g. common kick-off meeting and annual meetings).

2.Periodic report of joint activities (delivered at each reporting period).

3.Common dissemination and communication activities (which may include, for example: a common dissemination and communication strategy, web portal and visual identity, brochure, newsletters).

4.Common Data Management Strategy and Common Policy Strategy (including joint policy briefs).

5.Thematic workshops/trainings on issues of common interest.

6.Working groups on topics of common interest (e.g. data management and exchange, communication and dissemination, science-policy link, scientific synergies).

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Living and working in a health-promoting environment”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to most of the following expected outcomes:

1.Researchers, policymakers, healthcare practitioners and the public have a more comprehensive understanding of the human exposome and the interactions between climatic, environmental and socio-behavioural factors, supported by FAIR 102 data linking these exposures to disease and health outcomes.

2.Researchers, governments, policymakers, social care services and healthcare practitioners have improved knowledge on the links between the climatic, social, lifestyle and environmental factors of the exposome and global health burden, supporting their efforts to adopt the exposome approach to identify and address relevant health impacts.

3.The public has access to the latest information on the influence of global environmental exposures on health, enabling the adoption of health-promoting, climate-resilient and nature-positive behaviours.

Scope: The exposome is the totality of exposures (and their interactions) experienced by an individual throughout their lifetime, including chemical, physical, biological, nutritional and psychosocial factors, from conception onwards. Many of these factors originate in the environment, including climate-related exposures such as extreme heat, heightened air pollution or drought. Climate change may amplify or interact synergistically with other better-established exposures, dynamically altering the human exposome and its health implications. Despite this, climate factors remain underrepresented in large-scale human exposome studies.

Research activities under this topic should strengthen the use of the exposome approach to study global exposures and generate evidence on their health implications. Proposals should focus on integrating climate-related factors into exposome research and understanding how the exposome changes in response to direct and indirect climate exposures. Moreover, research activities should be multiscale and multidisciplinary and account for the complexity and multifactorial nature of health determinants and the most pressing unmet medical needs in relation to environmental degradation and disrupted ecosystems. Proposals should include climate-relevant social determinants of health as part of their proposed activities.

More specifically, research actions under this topic should include all the following activities:

1.Incorporate multiple climate exposures into exposomics studies and provide insights on their influence on disease burden, through interactions with other exposome factors.

2.Predict, identify and monitor changes in the exposome (including environmental, social and occupational exposures) resulting from climate-related pressures and study their health implications to identify emerging health risks and potential benefits of climate change.

3.Advance data generation, analysis, integration and interpretation in human exposomics, developing methodologies and integrating novel approaches (e.g. AI technologies and machine learning) for advanced data analytics, including for Real-World Data (RWD) 103 .

In addition, research actions should include several of the following targeted activities:

1.Establish and investigate the biological pathways and mechanisms by which the exposome drives health impacts, jointly considering climate-related and other exposures. Build upon (when relevant) and study existing and/or newly generated longitudinal cohorts that combine individual exposome data with the corresponding medical, omics and biological data.

2.Identify exposome-relevant indicators and biomarkers for exposome-related health risks and potential benefits using comprehensive exposome studies that combine climate, environmental, behavioural and social exposures. Account for disparities in individual trajectories and exposure patterns where relevant.

3.Report on health-relevant exposome findings using, where possible, standardised metrics to ensure harmonised reporting of exposome-driven disease burden across regions and sectors. Build on existing exposome toolboxes and increase their robustness and coverage by integrating climate related exposures.

4.Study the role of socioeconomic (e.g. income, energy poverty, occupation), demographic (e.g. gender, racial or ethnic origin 104 , age) and behavioural (e.g. public trust, risk perception) factors in determining patterns of exposure, using the exposome approach to generate knowledge on intersectional vulnerability and resilience to exposome-driven (including climate-driven) health impacts. Identify disproportionately affected populations and develop interventions to reduce disparities.

When handling vulnerability data and indicators, sex-, gender-, racial or ethnic origin 105 -disaggregated data should be collected and analysed, incorporating intersectional factors where feasible and relevant.

International cooperation is encouraged, in particular with regions that are under-represented in human exposome research.

Projects should leverage the knowledge, data and tools already generated under past initiatives such as EHEN 106 and ongoing initiatives such as IHEN 107 , ICOS ERIC 108 and EIRENE RI 109 .

Proposals are encouraged to consider, where relevant, the data, expertise and services offered by European research infrastructures 110 in the environment, climate and health domain. Projects should make the tools developed as part of their research available on the IHEN Exposome Toolbox 111 and upload their data sets in the IHEN Data Catalogue 112 .

In order to maximise synergies and increase the impact of the projects, all proposals selected for funding from this topic will form a cluster and be required to participate in common networking and joint activities. Guidance on the potential activities to be developed can be obtained by consulting the ongoing clusters of projects under the Environment, Climate and Health research portfolio 113 .

Proposals should make sure that relevant activities, outcomes and outputs are shared with the European Climate and Health Observatory 114 through the cluster that will be formed after the approval of the proposals.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

Applicants envisaging to include clinical studies 115 should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

HORIZON-HLTH-2027-01-ENVHLTH-MISSCLIMA-03: Tools and technologies to support health adaptation to climate change

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.00 and 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 20.00 million.

Type of Action

Pre-commercial Procurement

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

The specific conditions for actions with PCP/PPI procurements in section H of the General Annexes apply to grants funded under this topic.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries must ensure that the subcontracted work is performed in the EU and Associated Countries - unless otherwise approved by the granting authority.

Grants award under this topic will have to submit the following deliverable: To stimulate dialogue with the supply side, procurers are required to organise an open market consultation before launching the procurement and deliver a report on the outcomes of this consultation.

Beneficiaries will be subject to the following additional dissemination obligations: Procurers are required to promote the call for tenders widely across the EU and Associated Countries to potentially interested suppliers.

Beneficiaries may provide financial support to third parties to ensure the deployment and impact of the project outcomes. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000.

The specific conditions are described in General Annex H.

PCP procurement costs are eligible.

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Living and working in a health-promoting environment” and the EU Mission on Adaptation to Climate Change. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to most of the following expected outcomes:

1.Populations, public authorities and healthcare systems benefit from innovative solutions and technologies to increase surveillance and prevention and reduce climatic and environmental health risks.

2.Policymakers and public authorities develop and implement environment, climate change and health policies and interventions supported by nearly fit-for-use solutions that can be further upscaled and deployed.

Scope: Enhancing the adaptive capacity and resilience of healthcare systems and communities is crucial to prevent and reduce the health impacts of climate change. However, many of the urgently needed technologies, tools, systems and solutions are still at an early developmental stage, relying on further support for development and testing. Proposals under this topic are expected to close this gap and build on innovations being developed in the field, supported through, among others, EU Research and Innovation (R&I) funding. In this context, Pre-commercial Procurement (PCP) projects can drive innovation and speed up the development of technologies for health adaptation to climate change by supporting the research and development of solutions to increase the resilience and preparedness of healthcare systems, communities and individuals against climate change. By focusing on early-stage solutions, PCP fosters collaboration between public sector buyers (e.g. public authorities, local authorities, health organisations) and private developers to create climate adaptation technologies, systems and solutions in the context of human health. These solutions will accelerate the transition to more climate-resilient healthcare systems and societies.

PCP actions target consortia of procurers with similar needs that want to jointly procure the development of innovative solutions for supporting adaptation efforts. This topic does not provide direct funding to developers, industry or research organisations to perform Research and Development (R&D). They will be able to respond to the call for tenders launched by consortia of procurers funded under this topic.

Proposals under this topic should support the development of innovative solutions, tools and models to enhance surveillance, prediction, prevention, risk management and diagnosis (e.g. testing), supporting the adaptation, resilience, and preparedness of healthcare systems and populations to climatic and climate-related environmental health risks.

More specifically proposals can support any of the areas listed below:

1.Geospatial technologies and decision-support frameworks that help local authorities and healthcare providers track at “high resolution” and better manage direct and indirect health risks related to climate change.

2.Real-time risk surveillance and early-warning technologies and monitoring tools that provide critical information for timely decision-making and responses related to the health risks of climate change.

3.Technologies and solutions that facilitate the transition to climate-resilient healthcare facilities and services. Activities targeting the general infrastructure (e.g. ventilation, construction or refurbishment) are out of scope.

4.Technologies, tools, procedures and solutions for health risk management, prevention and resilience, enhancing strategies and interventions for health adaptation to climate change in communities and occupational settings.

5.Innovative tools reducing risk and exposure to climate related environmental factors that exacerbate health risks.

This topic considers tools and technologies that could be developed and tested to support adaptation at both the community and healthcare system levels 116 . This approach would comprehensively address the needs of health authorities and those of local authorities and public organisations involved in risk management. Consortium composition could include diverse stakeholders such as hospitals, primary healthcare providers, domestic care services, municipalities, civil protection entities and government agencies. The focus can extend beyond climate variables to include other related environmental and ecological factors (for example air pollution) that interact with climate change and impact public health.

Proposals are encouraged to consider, where relevant, the data, expertise and services offered by European research infrastructures 117 in the environment, climate and health domain.

Continuous dialogue between demand and supply side is required for the success of PCPs, therefore the effective involvement of end users should be considered in the proposal.

Involvement of procurement decision makers is needed to ensure that end solution(s) are adopted by healthcare systems and/or local authorities and public organisations increasing the societal impact of the related research activities. Therefore, procurers should declare in the proposal their interest to purchase at least one solution resulting from the PCP in case the PCP delivers successful solutions and indicate whether they will i) procure the solution(s) as part of the PCP or ii) in a separate follow-up procurement after the PCP. In the first case, procurers can implement the project as a fast-track PCP (see section H of the General Annexes of this Work Programme for further details) and foresee the budget to purchase at least one solution during the PCP. In the second case, the procurers should include in the proposal a deliverable that prepares the follow-up procurement to purchase successful solution(s) after the PCP.

This topic is co-financed by the EU Mission on Adaptation to climate change 118 and supports the follow up to the 2023 Communication on the Missions 119 . Projects are encouraged to channel their activities through the Mission Implementation Platform 120 and the Mission’s Community of Practice 121 .

Destination - Tackling diseases and reducing disease burden

Topics under this destination are directed towards the Key Strategic Orientation 3 “A more resilient, competitive, inclusive, and democratic Europe” of Horizon Europe’s strategic plan 2025-2027 122 .

Research and Innovation supported under this destination should contribute to the following expected impact, set out in the strategic plan impact summary for the Health Cluster: “healthcare providers improve their ability to tackle and manage diseases (infectious diseases, including poverty-related and neglected diseases, non-communicable and rare diseases) thereby reducing the disease burden on patients and enabling healthcare systems to perform more effectively. It can be achieved through better understanding, prevention, diagnostics, treatment, management, and cure of diseases and their co- and multi-morbidities, more effective and innovative health technologies and medical countermeasures, better ability and preparedness to manage pandemic and/or epidemic outbreaks, and improved patient safety”.

Communicable and non-communicable diseases pose a significant health, societal, and economic threat worldwide, causing premature deaths and disabilities. Despite being largely preventable, only 6% of healthcare budgets are spent on prevention 123 . To address this, there is an urgent need to develop new public health interventions, preventive, diagnostic, and therapeutic approaches, alternatives to antimicrobials, as well as to improve existing preparedness and response strategies to create tangible impacts, considering sex/gender-related issues. To address these challenges, Research and Innovation will require international cooperation to leverage global expertise, access world-class research infrastructures and invest in priority needs, aligning with other funders of international cooperation in health Research and Innovation. The continuation of international partnerships and cooperation with international organisations is particularly needed to combat infectious diseases and respond to public health needs, including rare diseases and the global burden of non-communicable diseases.

In this Work Programme part, Destination “Tackling diseases and reducing disease burden” will focus on major societal challenges linked to the Commission's Political Guidelines for 2024-2029 124 , such as the fight against non-communicable and communicable diseases, mental health, preparedness and response to and surveillance of health threats and epidemics, reduction and treatment, of Antimicrobial-Resistant (AMR) infections, coherent also with wider EU initiatives such as the European Medical Countermeasures Strategy 125 and the forthcoming Critical Medicines Act 126 . In particular, the topics under this destination will support activities aiming at: i) new treatment and disease management options to reduce burden on non-communicable diseases and long-term conditions after post-bacterial and post-viral infections; ii) improve and protect mental health of children and young adults; iii) new prevention and treatment options for infectious diseases with epidemic potential; iv) innovative therapies for AMR critical pathogens; and v) support to second phases of the co-funded European Partnership on Rare Diseases 127 and the co-funded European Partnership for Pandemic Preparedness 128 .

To increase the impact of EU investments under Horizon Europe, the Commission encourages cooperation between EU-funded projects to enable cross-fertilisation and other synergies. This could range from networking to joint activities, such as participating in joint workshops, exchanging knowledge, developing and adopting best practices, or undertaking joint communication activities. Opportunities for potential synergies exist between projects funded under the same topic, as well as between projects funded under different topics, Clusters, or Pillars of Horizon Europe. For example, synergies could be sought with projects funded under the European health research infrastructures (Pillar I of Horizon Europe), the EIC 129 strategic challenges on health (Pillar III of Horizon Europe), or with projects on themes that cut across the Clusters under Pillar II of Horizon Europe, such as health security/emergencies under Cluster “Civil Security for Society”, Artificial Intelligence (AI)-based tools and technologies under Cluster “Digital, Industry and Space”, or antimicrobial resistance under Cluster “Food, Bioeconomy, Natural Resources, Agriculture and Environment”.

The Commission aims to foster synergies between Horizon Europe and other EU programmes. To this end, applicants are encouraged to explore the funding opportunities available through the EU4Health Programme (2021-2027) 130 , the EU's public health programme, as a means of capitalising on potential collaborations and maximising impact.

Expected impacts: 

Proposals for topics under this destination should set out a credible pathway to contributing to tackling diseases and reducing disease burden, and more specifically to several of the following impacts:

1.Disease burden in the EU and worldwide is reduced through effective disease management, including through the development and integration of innovative preventive, diagnostic and therapeutic approaches, digital and other people-centred solutions for healthcare.

2.Premature mortality from non-communicable diseases is reduced by one third (by 2030), mental health and wellbeing are promoted, and the targets of the World Health Organization (WHO) Global Action Plan for the Prevention and Control of non-communicable diseases 131 , 132 are attained, with an immediate impact on the related disease burden (Disability-Adjusted Life Years - DALYs) 133 .

3.Healthcare systems benefit from strengthened Research and Innovation expertise, human capacities and know-how for combatting communicable and non-communicable diseases, including through international cooperation.

4.Citizens benefit from reduced (cross-border) health threat of epidemics and AMR pathogens, in the EU and worldwide 134 , 135 , 136 .

5.Patients and citizens are knowledgeable of disease threats, involved and empowered to make and shape decisions for their health, and better adhere to knowledge-based disease management strategies and policies (especially for controlling outbreaks and emergencies).

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in the Annex B of the General Annexes of this Work Programme.

The protection of European communication networks has been identified as an important security interest of the Union and its Member States. Entities that are assessed as high-risk suppliers 137 of mobile network communication equipment (and any entities they own or control) are not eligible to participate as beneficiaries, affiliated entities and associated partners to topics identified as “subject to restrictions for the protection of European communication networks”. Please refer to the Annex B of the General Annexes of this Work Programme for further details.

Proposals are invited against the following topic(s):

HORIZON-HLTH-2026-01-DISEASE-02: Innovative interventions to prevent the harmful effects of using digital technologies on the mental health of children and young adults

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 44.20 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Researchers and healthcare professionals have an improved understanding of the neuro-biological and cognitive/behavioural evidence base on the correlation and impact of digital technologies on mental health, including brain development.

2.Policymakers and digital technology and content developers are provided with a robust evidence base on the impact (positive or negative) of digital technologies on mental health in children and young adults 138 .

3.Policymakers, digital technology developers, and educational institutions amongst others make use (e.g. developing guidelines) of the evidence base and widely implement the newly developed interventions aimed at promoting children and young adults’ mental health while mitigating any negative impacts of digital technology use.

4.Children, young adults, families, guardians, educators, and carers have access to the newly developed interventions designed to prevent harm and promote the positive use of digital technologies.

5.Children and young adults are empowered and develop resilience, including digital literacy, enabling them to engage in a healthy and positive way with digital technologies.

Scope: Already before the COVID-19 pandemic, 1 in 6 people in the EU suffered from mental health issues. The economic costs of it are estimated at 4% of the Gross Domestic Product (GDP) 139 and since then these figures worsened 140  in particular among vulnerable groups such as children and adolescents or those at risk of discrimination. Digital technologies have the potential to enhance mental health for instance by providing access to information, support networks and therapy services 141 . However, there are indications that the excessive or misguided use of digital technologies, particularly among children and young adults, can negatively affect mental health and exacerbate mental disorders. There is an urgent need for more robust data to foster a safer, responsible and healthier use of digital technologies among children and young adults, prioritising the protection of their mental health.

Therefore, proposals should aim at generating robust scientific evidence on the impact of digital technologies, as well as developing and testing context-specific digital interventions that promote the positive and responsible use of them to improve mental health, avoiding the development or exacerbation of mental disorders. These innovative digital interventions should leverage multi-source data (e.g. sleep patterns, heart rate, stress levels, screen-time analytics, social media use, biological data, clinical data), and could include the use of Artificial Intelligence (AI). When handling data and indicators, sex and gender identity-disaggregated data should be collected and analysed, incorporating intersectional factors where feasible.

The applicants should address all the following aspects:

1.Generate the neuro-biological and cognitive/behavioural evidence base on the correlation and impact of digital technologies on mental health, including brain development (both positive and negative).

2.Develop and test innovative digital interventions aiming for example at: counteracting addictive design patterns (e.g. on social media and gaming platforms), gaining insights into risk patterns and enabling early risk detection (e.g. detecting early warning signs of mental disorders or digital addiction), redirecting users towards healthy use and positive engagement with digital technologies, and/or reducing exposure to harmful content.

3.Assess the changes in behaviour in children and young adults of the newly developed interventions, aiming at fostering their resilience and promoting responsible use and healthy digital habits.

The topic is open to address any mental disorder 142 caused or aggravated by the use of digital technologies such as addiction, self-harm behaviour, increased anxiety or decreased self-esteem, sleeping-disorders, post-traumatic stress disorders.

Cohort studies and clinical studies are in the scope for this topic. Applicants envisaging to include longitudinal cohort studies are invited to indicate a sustainability plan on how those cohorts are maintained over an extended period beyond the end period of the project for a long-term follow-up. They should make use of existing cohorts data when available. Applicants are welcome to consider recruiting participants transnationally and from diverse settings in the clinical study design to ensure generalizability of findings. In addition, it should be detailed in the proposal how the proposed intervention(s) could be scaled-up and transferred to other settings. Applicants should also consider the inclusion of end-users in the codesign of the interventions, for example for the young age groups, this includes the involvement of families, carers, educators. Applicants should access and make best-use of already existing European Research Infrastructures relevant for brain-research (e.g. EBRAINS 143 , Euro-BioImaging 144 ).

All projects funded under this topic should liaise with relevant European projects on mental health 145 and the future co-funded European Partnership for Brain Health 146 . They are also encouraged to explore potential synergies with projects to be funded under the EU4Health Work Programme 2026 related to the harmful effects of using digital technologies on the mental health of children and young adults.

The participation of start-ups and/or micro, small and medium-sized enterprises (SMEs) 147 is encouraged with the aim to strengthen their scientific and technological basis and valorise their innovations and to advance commercial exploitation.

Proposals should adhere to the FAIR 148 data principles, adopt wherever relevant, data standards and data sharing/access good practices, and apply good practices for GDPR 149 compliant personal data protection.

The topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities. The support and involvement of citizens and civil society should be considered.

Applicants should provide details of their clinical studies 150 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2026-01-DISEASE-03: Advancing research on the prevention, diagnosis, and management of post-infection long-term conditions

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 39.30 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 151 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.All players along the healthcare value chain have access to evidence-based treatment and management strategies for post-infection conditions and improve patient recovery and quality of life across diverse populations.

2.Public health authorities and healthcare practitioners have access to effective prevention, diagnostic and treatment tools, ensuring better allocation of healthcare resources.

3.Healthcare systems improve their efficiency and reduce long-term economic burdens by streamlining post-infectious disease care and addressing disparities in healthcare access.

4.Public health authorities have access to evidence-based information to integrate research findings into policy for improved public health preparedness and resilience, including training of healthcare staff and enhanced long-term disease management guidelines.

Scope: Microbial infections can lead to long-lasting consequences on patients’ quality of life, leading to long-term conditions characterised by persistent inflammation, organ damage, and impaired functional capacity, which pose a growing public health and economic challenge. These conditions are insufficiently understood, underdiagnosed, and lack effective treatments. Advancing research into their prevention, treatment and management is essential to improving patient outcomes, reducing healthcare burdens, and strengthening workforce productivity.

The topic is open to long-term conditions resulting from infections by any type of microorganism (including viruses, bacteria, parasites, and fungi), which persist after the initial infection has been resolved. Research linked to cancer is excluded as it will be covered by the Cancer Mission.

Proposals should aim to develop innovative approaches for the prevention, diagnosis, and management of post-infection conditions. Proposals should address most of the following research areas:

1.Identify protective and risk factors associated with the development of post-infection conditions to inform targeted prevention strategies, by integrating relevant information such as genetics, epigenetics, immune or inflammatory responses, and/or other relevant factors.

2.Increase understanding of the pathophysiology of post-infection conditions (including inflammatory aspects) to identify biomarkers and develop clinically validated diagnostic approaches for early detection, disease progression and/or treatment optimisation.

3.Develop and validate preventive and/or therapeutic interventions, including targeted pharmacological treatments, repurposing of existing drugs or precision medicine approaches, through early-stage clinical trials 152 that demonstrate clinical safety and efficacy.

4.Identify effective supportive rehabilitation approaches, including physical therapy, cognitive interventions, and psychological support, to enhance patient recovery, mental health and quality of life and evaluate their effectiveness.

5.Examine best practices for integrating post-infectious disease management into primary and specialised healthcare settings, improving coordination among healthcare professionals.

Specific attention should be given to sex and gender, as women often experience post-infectious diseases differently due to hormonal and other biological, as well as social factors, which can affect their diagnosis, treatment, and recovery. Moreover, age, disability, racial or ethnic origin 153 , socio-economic, lifestyle and behavioural factors should also be considered. Particular emphasis should be placed on populations in a vulnerable situation and groups with pre-existing conditions to ensure equitable and inclusive healthcare solutions.

A multidisciplinary, cross-sectoral approach is encouraged, involving all relevant stakeholders (medical and non-medical), including patients, researchers, healthcare professionals, and policymakers.

Proposals should develop a harmonised approach to collection, storage, sharing and analysis of FAIR 154 data, leveraging existing European (research) infrastructures, including biobanks or cohorts’ data 155 where relevant and contribute to emerging research infrastructures, established in the framework of the European Health Data Space (EHDS) 156 and the European Open Science Cloud (EOSC) 157 .

Proposals should demonstrate complementarity with ongoing EU initiatives, including projects funded under relevant topics 158 , and outline plans for collaboration where applicable, to maximise synergies and avoid duplication of research efforts.

All projects funded under this topic are expected to participate in networking and joint activities 159 . They are also expected to engage early on with the European Medicines Agency (EMA) to ensure adequacy of the actions from a regulatory point of view. Where relevant, a Health Technology Assessment (HTA) should be conducted to evaluate the clinical, economic, and social implications of interventions.

If applicable, applicants are encouraged to incorporate artificial intelligence (AI) tools and advanced computational modelling/Virtual Human Twin (VHT)-powered tools to predict disease risk and progression, ensuring these tools are developed and tested for diverse populations to minimise bias. Hardware and software should be interoperable in line with internationally accepted standard.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

Participation of start-ups, micro, small and medium-sized enterprises (SMEs) 160 is also encouraged to strengthen their scientific and technological foundations and enhance their innovation potential.

Applicants should provide details of their clinical studies 161 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2026-01-DISEASE-04: Development of novel vaccines for viral pathogens with epidemic potential

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 9.00 and 11.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 44.20 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced project portfolio covering the viruses targeted in this topic 162 , grants will be awarded (within available budget) to proposals not only in order of ranking but at least also to those proposals that are the highest ranked within different viruses targeted, provided that the proposals attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.The scientific and clinical communities have a better understanding of and access to experimental vaccines for the prevention and treatment of emerging or re-emerging viral infections, as well as for further clinical investigation, including better understanding of biological sex and social determinants that influence immune response, vaccine efficacy, safety, and uptake.

2.Candidate vaccines are available for emerging and re-emerging viral infections, increasing therapeutic options for clinical deployment in case of an epidemic or pandemic.

Scope: Infectious diseases remain a major threat to health and health security in the EU and globally. Viral disease emergence is already being accelerated by climate change, and thus a proactive approach to the development of vaccine-based antiviral prophylactics and therapeutics in preparedness for future infectious disease outbreaks is needed. The availability of vaccines that can be adjusted to variants would provide a critical preparedness measure against future health threats, due to infectious disease epidemics or pandemics.

This topic contributes to strengthening the Research and Innovation ecosystem within the EU and supports the implementation of the European Medical Countermeasures Strategy 163 .

Applicants should explicitly state in their proposal which of the following viruses is targeted and the proposed work should address only this specific virus. The proposed work should aim to advance the development of existing prophylactic and therapeutic vaccine candidates targeting exclusively one of the following viruses:

1.Junin mammarenavirus

2.Lassa mammarenavirus

3.Andes virus,

4.Hantaan virus

5.Sin Nombre virus

6.Hendra virus

7.Enterovirus D68

8.Venezuelan equine encephalitis virus

Proposals should thus aim to diversify and accelerate the global prophylactic and therapeutic research and development portfolio for emerging and re-emerging viral infections, and to strengthen the leading role of the EU in prophylactic and therapeutic research and development.

Proposals should address all the following research areas:

1.If necessary, finalisation of the in-vitro characterisation of existing vaccine candidates with regard to target specificity, epitope recognised, and their ability to impair or inactivate viral functions.

2.In-vivo tests in at least one animal model or, if available in humanised immune system animal models, to demonstrate the protective function of the vaccine candidates deemed sufficient for moving to first clinical trials.

3.If requested by regulators as pre-requisite for clinical studies, in-vivo tests in a non-human primate model.

4.Production of batches of the most promising vaccine candidates according to the Good Manufacturing Practices (GMP) 164 .

5.First in human clinical safety studies demonstrating a clear regulatory pathway for market authorisation. Attention should be paid to critical biological and social factors such as sex, age, ethnicity and disability.

Participation of third countries where viruses addressed in the proposal are endemic or where outbreaks have occurred or are ongoing is encouraged.

The European Commission's Joint Research Centre (JRC) may contribute to the proposals selected for funding with work on strategic technologies for economic security and innovative industrial ecosystems, particularly activities on innovation in vitro biotechnologies.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 165 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

All projects funded under this topic are expected to engage with regulatory bodies in a timely manner to ensure adequacy of the actions from a regulatory point of view.

Proposals should advance research by leveraging already existing and emerging state-of-the-art research infrastructures 166 such as those having contributed to the services developed under the ISIDORe project 167 .

Applicants should provide details of their clinical studies 168 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2026-01-DISEASE-09: Multisectoral approach to tackle chronic non-communicable diseases: implementation research maximising collaboration and coordination with sectors and in settings beyond the healthcare system (GACD)

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 9.80 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 169 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to some of the following expected outcomes:

1.Researchers, policymakers, healthcare- and non-healthcare-related stakeholders and authorities in low- and middle-income countries (LMICs) 170 and/or those in high-income countries (HICs) serving disadvantaged populations have access to improved insights and evidence on how to maximise collaboration and coordination with sectors and in settings beyond the healthcare system in the context of Non-Communicable Diseases (NCDs).

2.Researchers, policymakers, healthcare- and non-healthcare-related stakeholders and authorities have an improved understanding how the proposed interventions draw on collaborative multisectoral engagement and utilise the different settings in which people are educated, work and live, to expand efforts to reduce risks, prevent, manage and control NCDs.

3.Communities, relevant stakeholders from different sectors and authorities are fully engaged in implementing and taking up interventions that tackle the growing burden of NCDs through actions in sectors and settings outside the traditional health system and its facilities health-related outcomes, improve quality of life across the life course and extend healthy life expectancy.

Scope: The Commission is a member of the Global Alliance for Chronic Diseases (GACD) 171 . The GACD specifically addresses NCDs and supports implementation research 172 to improve health outcomes. This topic is launched in concertation with the other GACD members (international funding agencies) and aligned with the 11th GACD call.

Besides health-related determinants, the burden of NCDs is also driven by structural and social inequities, population ageing, the effects of globalisation on marketing and trade, diet and activity, commercial and economic determinants of health, rapid urbanisation and climate change, factors over which a conventional healthcare-oriented system has little sway. There is a need for a comprehensive approach, involving sectors outside of health, to meet the global targets that governments have agreed upon to protect people from chronic NCDs. Tackling chronic NCDs most effectively therefore requires engagement and coordinated policy development within and across many government departments, including education, workplace, environment, social systems, housing, transportation, agriculture, food industry and nutrition, leisure and culture.

The aim of this topic is to fund implementation research focused on strategies to tackle the growing burden of NCDs through actions in sectors and settings outside the traditional health system 173 and its facilities (with or without the involvement of the healthcare system) to attain equitable health-related outcomes or influence health determinants for people living in LMICs, and/or underserved populations in HICs.

Proposals can focus on more than one setting and/or include cross-sectoral approaches, involving both health and non-health settings to expand efforts to reduce risks, prevent, manage and control NCDs. Safety is a major concern in non-health settings, and proposals should ensure any risks and safety considerations are addressed.

The choice of intervention(s) 174 and provision of existing evidence of the intervention’s effectiveness, cost-effectiveness, sustainability, scalability and potential for long-term health and other impacts should be justified (and in what context this evidence has been generated).

The majority of evidence-based interventions implemented outside of the health sector focus on prevention of NCDs: relatively few focus on strategies for management of these chronic conditions, and a limited number are implemented in LMIC contexts or underserved communities. Therefore, it may be important to undertake formative research as a part of the proposal to support readiness for implementation.

Applicants should explore the implementation of proposed intervention(s) for a selected study population(s) based in one or more LMICs, and/or underserved populations experiencing health disparities, including Indigenous populations, in HICs, considering the unique social, political, economic, and cultural context(s) in which the study will take place 175 . Applicants should justify why any adaptation will not compromise the known effectiveness of the selected intervention(s).

Proposals should address all the following implementation research activities 176 :

1.Clearly describe the implementation research methodology, including the statistical design, and provide a rationale for the implementation strategy/ies to be explored (in light of the context), the community/population group(s) to benefit, the settings and sectors involved (and how these should be engaged), the current state of the art and how the proposal improves on this, and, if used, the theories, models and/or frameworks underpinning the research.

2.Have an appropriate strategy for measuring implementation research outcomes and real-world effectiveness outcomes and indicators.

3.Specifically address issues of equitable implementation to ensure interventions reach the populations that need them the most.

4.Engage an appropriately expert and skilled research team which can ensure a suitable multidisciplinary approach and that demonstrates equitable partnership and shared leadership between HIC-LMIC, and/or non-Indigenous-Indigenous members of the project team and external stakeholders through a clear governance strategy.

5.Provide a stakeholder engagement strategy with evidence of support/engagement from key stakeholders for delivering the intervention and a pathway to sustain the proposed intervention (if proven effective) after the funding from the GACD grant ends.

6.Provide opportunities for implementation research capacity building for early career researchers and team members from lower resourced environments, such as LMICs or disadvantaged communities.

7.Ensure meaningful involvement of early career team members, including at least one early career member as a co-investigator.

The study population may include the general population, people with one or more existing NCDs, those currently without NCDs, or a combination of both. Applicants may propose implementation research focused on interventions that are implemented at the individual, family, community (e.g. work or school), population, and/or structural level. With regard to NCDs, applicants are encouraged to explore any chronic non-communicable condition (or combination of conditions), including mental health disorders, substance use disorders, autoimmune conditions, musculoskeletal conditions, neurological disorders and sleep disorders and/or any risk factor (or combination of risk factors). Additionally, whenever relevant, applicants are also encouraged to take a life course approach, adapting interventions for particular life stages with the goal of promoting life-long health.

Proposals should use an appropriate implementation research design and frameworks 177 , cluster Randomised Control Trials (cRCTs), before and after studies, and additional implementation science classifications of study designs (e.g. hybrid designs 178 ), noting that applicants are not limited to any particular design.

Proposals are expected to generate evidence that is of direct relevance to policymakers, communities and practitioners. Proposed work should develop a strategy to include the relevant policymakers, local authorities, as well as other stakeholders such as community groups, or other individuals or organisations involved in the implementation of the intervention, with co-creation from the development of the proposal through to the knowledge translation phase. Project partners should be engaged from the beginning to contribute to the sustainability of the intervention after the end of project. Proposals should demonstrate sustainability of the strategy, beyond the lifespan of the project.

Poverty, discrimination based on sex, racial or ethnic origin 179 , religion or belief, disability, age, and other inequities are directly associated with reduced potential for equitable access to quality care. Proposals should consider relevant determinants of health (e.g. social, structural, commercial, economic) and discuss their potential impact on the effective implementation of the intervention(s). If there is a focus on a particular population (e.g. gender, racial or ethnic origin 180 , etc.), then the reason for this should be justified.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

All projects funded under this topic are strongly encouraged to participate in networking and joint activities, including internationally, as appropriate. These activities could, for example, involve the participation in joint workshops, the Annual Scientific Meetings of the GACD, the exchange of knowledge, the development and adoption of best practices, or joint communication activities. Therefore, proposals are expected to include a budget for such activities and should consider covering the costs of any other potential joint activities without the prerequisite to detail concrete joint activities at this stage. The details of these joint activities will be defined during the grant agreement preparation phase.

Applicants should provide details of their clinical studies 181 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 7.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 39.30 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 182 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Researchers, developers of medical interventions, and healthcare professionals have a better understanding of biological sex and/or gender-specific health determinants, risk factors and pathways for cardiovascular diseases.

2.Researchers, developers of medical interventions, and healthcare professionals have access and use sex and/or gender-specific or tailored risk models for better prevention, detection and diagnostic and treatment strategies.

3.Healthcare systems benefit from novel sex and/or gender-specific strategies for prevention, detection, diagnosis and treatment options, resulting in reduced burden of cardiovascular diseases.

Scope: Cardiovascular diseases (CVDs) are the leading cause of premature deaths in the EU and account for 32% of all deaths in 2021 (over 1.7 million deaths) 183 .

Biological sex and gender play a specific role both in the incidence and the prevalence of certain diseases, including CVDs. Sex and gender disparities in CVDs are influenced by biological, behavioural, and sociocultural factors, affecting symptoms, prevalence, treatment, and outcomes. Hormonal influences, genetic predispositions, and/or physiological differences contribute to variations in how CVD presents and progresses in men and women. Risk factors such as diabetes, cholesterol, smoking, and age have different impacts across genders, highlighting the need for customised treatment strategies. Unique gender-specific conditions in women, such as menopause, pregnancy complications like preeclampsia and certain autoimmune diseases, also increase the risk for CVDs 184 .

Mainstreaming a gender perspective into the research, prevention and control of CVDs is thus crucial to understanding and addressing the health risks and needs of women and men of all ages 185 .

Although the significant progress has been done in investigating sex and/or gender-specific pathophysiological mechanisms of cardiovascular diseases, more research is needed to translate basic discoveries into the development of innovative prevention, detection, diagnosis, and treatment options.

Proposals should address most of the following aspects:

1.Contribute to further the understanding on the structural, hormonal, and/or biological distinctions between sexes/genders to improve diagnostics and therapeutics for CVDs.

2.Develop sex and/or gender-specific tailored risk models in a view of better prevention, detection and diagnostic, and treatment strategies.

3.Identify and/or validate novel or existing sex and/or gender-specific health determinants, risk factors and pathways for cardiovascular disease(s) through the generation, integration and validation of data derived from relevant disciplines (e.g. molecular biology, behavioural science, nutrition, clinical, social and environmental epidemiology; exposure sciences; genetics and epigenetics, etc.).

4.Make use of existing health data, including registries or cohorts, and/or assess the necessity to establish new ones, as well as, where relevant, exploit the knowledge gained from population-based biobanks. In case of the generation of new data, it should be managed in line with the FAIR 186 principles, when relevant.

Proposals are encouraged to consider, where relevant, the data, expertise and services offered by European research infrastructures 187 in the health domain.

The use and/or development of new technologies, including digital ones (e.g. (generative) Artificial Intelligence) that support research under this topic is encouraged.

Disease progression and overall health status at different life stages, as well as hormonal influences, genetic factors, etc. and psychosocial, socioeconomic, cultural and behavioural factors should be considered in the proposed research. Other intersecting factors such as racial or ethnic origin 188 , often amplify existing inequalities in health access and outcomes. Proposals should, where relevant, consider these to design effective and inclusive interventions.

In the context of gender-specific research, this topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 189 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

All projects funded under this topic are encouraged to participate in networking and joint activities, as appropriate. Proposals should include a budget for the attendance to regular joint meetings and may consider covering the costs of any other potential joint activities without the prerequisite to detail concrete joint activities at this stage. The details of these joint activities will be defined during the grant agreement preparation phase. All projects funded under this topic are also encouraged to explore complementarities and exploit potential synergies with the projects funded under topic HORIZON-CL6-2026-02-FARM2FORK-10: “Sustainable and healthy diets based on health status and socio-economic risk factors of ageing population”, once information on the funded projects is available.

All projects funded under this topic are encouraged to explore potential synergies with projects to be funded under the EU4Health Work Programme 2026 related to the gender and CVDs.

Applicants envisaging to include clinical studies 190 should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

HORIZON-HLTH-2026-02-DISEASE-12: European Partnership on Rare Diseases (ERDERA) (Phase 2)

Call: Partnerships in Health (2026/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 91.30 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 91.30 million.

Type of Action

Programme Co-fund Action

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The proposal must be submitted by the coordinator of the consortium funded under topic HORIZON-HLTH-2023-DISEASE-07-01: “European Partnership on Rare Diseases”. This eligibility condition is without prejudice to the possibility to include additional partners.

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding. Because the US contribution will be considered for the calculation of the EU contribution to the partnership, the concerned consortium of research funders from eligible EU Members States and Associated Countries must expressly agree to this participation.

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The evaluation will take into account the existing context and the scope of the initial evaluation as relevant, and related obligations enshrined in the grant agreement.

If the proposal is successful, the next stage of the procedure will be grant agreement amendment preparations.

If the outcome of amendment preparations is an award decision, the coordinator of the consortium funded under topic HORIZON-HLTH-2023-DISEASE-07-01: “European Partnership on Rare Diseases” will be invited to submit an amendment to the grant agreement, on behalf of the beneficiaries.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

This action is intended to be implemented in the form of an amendment of the grant agreement concluded pursuant to Article 24(2) of the Horizon Europe Regulation.

For the additional activities covered by this action:

1.The funding rate is 50% of the eligible costs. This is justified by the pooling of proposers' in-kind contributions and in-house activities and by the nature of activities to be performed: in addition of joint calls, highly integrative activities (EU clinical trial preparedness, training, patients’ empowerment activities etc.) contributing to enhance the rare disease research and innovation ecosystem in the EU and Associated Countries, and beyond.

2.Beneficiaries may provide financial support to third parties (FSTP). The support to third parties can only be provided in the form of grants. As a co-funded European Partnership, providing financial support to third parties is a core activity of this action in order to achieve its objectives. Consequently, the EUR 60 000 threshold laid down in Article 207 of Financial Regulation (EU, Euratom) 2024/2509 does not apply. The maximum amount of FSTP that may be awarded to any single third party for the duration of the partnership is set at EUR 10.00 million. This ceiling is justified by the fact that FSTP is a primary activity of this action, by its expected duration of 7-10 years (exceeding a standard project lifespan), and by the extensive experience gained under predecessor partnerships. This ceiling is also justified by the fact that research on rare diseases, in particular clinical research, is complex and costly to put in place due to the scarcity, for each disease, of patients, of knowledge, of clinicians and of researchers, and by the request, if possible, to group diseases for research purposes, in order to tackle several diseases out of the estimated 6-8.000 rare diseases. However, if the objectives of the action would otherwise be impossible or overly difficult (and duly justified in the proposal) the maximum amount may be higher.

3.The starting date of the grant awarded under this topic may be as of the submission date of the application. Applicants must justify the need for a retroactive starting date in their application. Costs incurred from the starting date of the action may be considered eligible (and will be reflected in the entry into force date of the amendment to the grant agreement).

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Total indicative budget

The total indicative budget for the topic is EUR 91.3 million committed in annual instalments over the two years, 2026 and 2027 (EUR 48.7 million from the 2026 budget and EUR 42.6 million from the 2027 budget).

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.The EU is reinforced as an internationally recognised driver of research and innovation in Rare Diseases (RD) and thereby substantially contributing to the achievement of the Sustainable Development Goals related to rare diseases.

2.Research funders align, adopt and implement their RD research policies allowing for the optimal generation and translation of knowledge into meaningful health products and interventions responding to the needs of people living with a rare disease across Europe and globally.

3.The RD research community at large benefit from and use an improved comprehensive knowledge framework and cross-border FAIR 191 data access and analysis, including rare diseases registries, by integrating the EU, national/regional data and information infrastructures to improve translational research.

4.People living with a rare disease, including those from underrepresented communities, benefit from a more timely, equitable access to innovative, sustainable and high-quality healthcare including novel diagnosis and treatments, taking stock of highly integrated research and healthcare systems.

5.Researchers, innovators -as well as people living with a rare disease and their advocates (as co-creators)- effectively constitute and operate into an integrated research and innovation ecosystem to deliver cost-effective diagnosis and treatments.

6.Public and private actors, including civil society (e.g. Non-Governmental Organisations, charities), establish coordinated and efficient multi-stakeholder collaborations at EU and national (including regional) levels, allowing for more effective clinical research, for example aiming at improved success rates of therapeutic development.

Scope: This topic targets an action under Article 24(2) HE Regulation aiming to add additional activities to existing grant agreements, together with additional partners (if relevant) that would deliver on those activities. The award of a grant to continue the partnership in accordance with this call should be based on a proposal submitted by the coordinator of the consortium funded under topic HORIZON-HLTH-2023-DISEASE-07-01: “European Partnership on Rare Diseases” and the additional activities (which may include additional partners) to be funded by the grant should be subject to an evaluation. Taking into account that the present action is a continuation of the topic HORIZON-HLTH-2023-DISEASE-07-01: “European Partnership on Rare Diseases” and foresees an amendment to an existing grant agreement, the proposal should present the additional activities (including additional partners) to be covered by the award primarily in terms of grant agreement revisions. The existing action, the “European Rare Diseases Research Alliance” (ERDERA) can only reasonably be enhanced and enlarged on the basis of the existing consortium 192 , as the co-funded framework established cannot simply be replaced without significant disruption, given the top-quality, long-term expertise and wide coverage of the beneficiaries comprising this consortium.

The proposal should thus present the specific additional activities (including, if relevant, additional partners) foreseen for the second instalment of the partnership. The partnership should continue to contribute to priorities of the communication “On effective, accessible and resilient health systems” (COM(2014) 215 final) 193 , the “Communication from the Commission on enabling the digital transformation of health and care in the Digital Single Market; empowering citizens and building a healthier society” (COM(2018) 233 final) 194 , the "Council conclusions on the Future of the European Health Union: A Europe that cares, prepares and protects" (9900/24) 195 and support the objectives of the EU4Health Programme (2021-2027) 196 .

This partnership should also contribute to achieving the objectives of the Pharmaceutical Strategy for Europe 197 , in terms of fulfilling unmet medical needs and catalysing the clinical development of medicines for rare diseases (i.e. “orphan medicinal products”) and ensuring that the benefits of research and innovation reach patients in the EU and the Associated Countries. Moreover, the partnership is expected to contribute and align with the objectives of the Directive 2911/24/EU on the application of patients’ rights in cross-border healthcare 198 and of the European Health Data Space (EHDS) 199 .

Thanks to its capacity to bring together different stakeholders (e.g. research funders, health authorities, healthcare institutions, innovators, policymakers), the partnership will strengthen the European Research Area and consolidate the European research and innovation ecosystem with a critical mass of resources, and implement a long-term Strategic Research and Innovation Agenda (SRIA) 200 .

The co-funded European Partnership on Rare Diseases should be implemented based on the priorities identified in the SRIA and through a joint programme of activities ranging from coordinating and funding transnational and clinical research to highly integrative and community-driven ‘in-house’ activities such as innovation strategies for the efficient exploitation of research results, EU clinical trial preparedness activities, optimisation of research infrastructures 201 and resources, including networking, training and dissemination activities. To this end, proposals are expected to build on the first phase of this partnership and should be structured along the following main objectives:

1.Launch joint transnational calls for RD research and innovation actions, aligned with SRIA priorities, to fund patient-need-driven research across Europe, ensuring effective cross-border collaboration and scalability, while demonstrating short, medium and long-term impact and value creation through financial support to third parties and a rigorous monitoring strategy of research outputs.

2.Further establish, strengthen and develop the different components of a European Clinical Research Network (CRN) to boost clinical trial readiness and capacity to readily implement well-coordinated multi-national clinical studies on rare diseases, building on the European Reference Networks (ERNs). The partnership is expected to showcase the CRN’s contribution to the cost-effective therapeutic development and decrease in diagnostic timelines linked with improvement in health outcomes ensuring durable collaboration among research, clinical, and regulatory actors.

3.Advance and consolidate the capacity building of the RD data ecosystem by supporting interoperable and/or federated cross-border access and analysis of FAIR research and healthcare data, including rare disease registries, ensuring ongoing their usability more efficient translational and clinical research, including regulatory science. The relevant European research infrastructures in the area of health should be exploited for available services, expertise and digital tools for the management and analyses of FAIR health data, as appropriate.

4.Integrate basic, pre-clinical, clinical and implementation research to streamline the Research and Innovation (R&I) continuum and minimise redundancies, ensuring lasting impact on the quality of life of the people living with a rare disease while strengthening systemic efficiency and cost-effectiveness. To that end, the partnership should mobilise a significant investment to spur innovation, by aligning regional, national and European R&I priorities and improving EU competitiveness in R&I.

5.Support research and innovation across key intervention areas (prevention, diagnosis, treatment), and promote the sustainable uptake of existing health innovations in clinical practice through coordinated training, implementation research, and active stakeholder engagement.

6.Contribute to and align with the International Rare Disease Research Consortium (IRDiRC) 202 to reinforce Europe’s global leadership, ensure policy coherence, and sustain long-term strategic alignment beyond the lifetime of the partnership. To that end, an optimised assessment of the European contribution to IRDiRC would be beneficial to ensure complementarity and avoid overlaps.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

Collaboration with the European Commission's Joint Research Centre (JRC) should be considered to materialise the sharing of (meta)data regarding registries for rare diseases, exchanging data for clinical studies and research based on a unified pseudonymisation tool provided by the European Platform on Rare Disease Registration (EU RD Platform) and related tools and services, as well as in other areas of mutual interest, such as training and capacity building.

HORIZON-HLTH-2026-03-DISEASE-13: European Partnership for Pandemic Preparedness (Phase 2)

Call: Partnerships in Health (2026/2)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 63.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 63.00 million.

Type of Action

Programme Co-fund Action

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The proposal must be submitted by the coordinator of the consortium funded under topic HORIZON-HLTH-2024-DISEASE-12-01: “European Partnership for Pandemic Preparedness”. This eligibility condition is without prejudice to the possibility to include additional partners.

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding. Because the US contribution will be considered for the calculation of the EU contribution to the partnership, the concerned consortium of research funders from eligible EU Members States and Associated Countries must expressly agree to this participation.

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The evaluation will take into account the existing context and the scope of the initial evaluation as relevant, and related obligations enshrined in the grant agreement.

If the proposal is successful, the next stage of the procedure will be grant agreement amendment preparations.

If the outcome of amendment preparations is an award decision, the coordinator of the consortium funded under topic HORIZON-HLTH-2024-DISEASE-12-01: “European Partnership for Pandemic Preparedness” will be invited to submit an amendment to the grant agreement, on behalf of the beneficiaries.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

This action is intended to be implemented in the form of an amendment of the grant agreement concluded pursuant to Article 24(2) of the Horizon Europe Regulation.

For the additional activities covered by this action:

1.The funding rate is 50% of the eligible costs. This is justified by the pooling of proposers' in-kind contributions and in-house activities and by the nature of activities to be performed: in addition of joint calls, sustain and further develop the EU-wide networks and infrastructures for clinical research, and in particular a network of ever-warm clinical trial sites.

2.Beneficiaries may provide financial support to third parties (FSTP). The support to third parties can only be provided in the form of grants. As a co-funded European Partnership, providing financial support to third parties is a core activity of this action in order to achieve its objectives. Consequently, the EUR 60 000 threshold laid down in Article 207 of Financial Regulation (EU, Euratom) 2024/2509 does not apply. The maximum amount of FSTP that may be awarded to any single third party for the duration of the partnership is set at EUR 3.00 million. This ceiling is justified by the fact that FSTP is a primary activity of this action, by its expected duration of 7-10 years (exceeding a standard project lifespan), and by the extensive experience gained under predecessor partnerships. This ceiling is also justified by the fact that the FSTP will support infectious diseases research involving multi-country research networks and infrastructures as well as their coordination. However, if the objectives of the action would otherwise be impossible or overly difficult (and duly justified in the proposal) the maximum amount may be higher.

3.The starting date of the grant awarded under this topic may be as of the submission date of the application. Applicants must justify the need for a retroactive starting date in their application. Costs incurred from the starting date of the action may be considered eligible (and will be reflected in the entry into force date of the amendment to the grant agreement).

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Total indicative budget

The total indicative budget for the topic is EUR 63 million committed in annual instalments over the two years, 2026 and 2027 (EUR 30 million from the 2026 budget and EUR 33 million from the 2027 budget).

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. Proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.The EU offers a valued operational network of clinical research sites (both interventional and observational) that have the capacity to implement well-coordinated large-scale multi-country quality clinical studies in different target populations, which are able to smoothly transition to interventions relevant for cross-border health threats in readiness for or response to a public health emergency.

2.Key stakeholders, including relevant EU and national entities, the scientific communities, policymakers and funders enhance their collaboration and coordination to strengthen research on pandemic preparedness and response, forming a strong, structured and comprehensive ecosystem with shared evidence, tools and methodologies cutting across sectors.

3.Research funders, policymakers, relevant EU and national entities, and the research community recognise and rapidly close relevant research and related infrastructure gaps and break existing silos on pandemic preparedness research and response, adopting a One Health approach.

4.Healthcare authorities, regulatory authorities, policymakers and other stakeholders utilise research results to develop evidence-based strategies and policies for pandemic preparedness and response, and deploy good practices to European countries and regions, and beyond whenever relevant.

5.The research community benefits from and uses an improved comprehensive knowledge framework integrating the EU, national/regional data and information infrastructures to improve transnational research in the area of pandemic preparedness and response.

6.The EU is strengthened as an internationally recognised actor for pandemic preparedness research and response, as such substantially contributing to global cooperation and coordination.

Scope: This topic targets an action under Article 24(2) HE Regulation aiming to add additional activities to existing grant agreements, together with additional partners (if relevant) that would deliver on those activities. The award of a grant to continue the partnership in accordance with this call should be based on a proposal submitted by the coordinator of the consortium funded under topic HORIZON-HLTH-2024-DISEASE-12-01: “European Partnership for Pandemic Preparedness” and the additional activities (which may include additional partners) to be funded by the grant, such as the close coordination with the Clinical Trial Coordination Mechanism (CT-CM) 203 , should be subject to an evaluation. The partnership should be firmly anchored within the framework of the European Health Union package 204 and ensure synergies with the European Health Emergency Preparedness and Response Authority (HERA) and other relevant Commission services. The partnership’s activities are expected to be key enablers of the EU Global Health Strategy 205 . Taking into account that the present action is a continuation of the topic HORIZON-HLTH-2024-DISEASE-12-01: “European Partnership for Pandemic Preparedness” and foresees an amendment to an existing grant agreement, the proposal should present the additional activities (including additional partners) to be covered by the award primarily in terms of grant agreement revisions. The existing action, the “Be Ready Now - European Partnership for Pandemic Preparedness” (BE READY NOW) can only reasonably be enhanced and enlarged on the basis of the existing consortium 206 , as the co-funded framework established cannot simply be replaced without significant disruption, given the top-quality, long-term expertise and wide coverage of the beneficiaries comprising this consortium.

The partnership should contribute to the actions proposed in the Joint Communication on the European Preparedness Union Strategy (JOIN(2025) 130 final 207 ) which recognises the essential contribution of research and innovation to allow “continuously adapted, optimised and state-of-the-art responses to crisis”. It should also contribute to the “Strategy for European Life Sciences” 208 . Synergies with EU programmes such as EU4Health Programme (2021-2027) 209 or the Digital Europe Programme 210 are encouraged.

The co-funded Partnership for Pandemic Preparedness should enable improved coordination and cooperation on national and European levels (and contributing globally), building on the Strategic Research and Innovation Agenda (SRIA) 211 established in the first phase of the partnership. The partnership’s implementation is grounded in coordinating and jointly funding transnational research, combined with a strong focus on integrative ‘in-house’ activities, ultimately reinforcing the readiness of Europe’s research ecosystem. As a continuation of an existing action, the proposal should present the additional activities (including additional partners) to be covered by the award primarily in terms of grant agreement revisions.

The partnership should cover the full scope of preparedness research, ranging from basic and pre-clinical research, to clinical, public health, social sciences and implementation research. The partnership will consider the interplay between environmental, ecological and climatic factors and the emergence and spread of health threats and will adopt a One Health approach to better understand and mitigate the risks of emerging infectious diseases.

Of particular interest is the consolidation and further development of the ever-warm clinical research network, comprising both observational and interventional studies, ensuring continuous clinical research activity across diverse sites, and with the in-built capacity to rapidly respond to public health emergencies. In this regard, the partnership should ensure that provisions are in place for the close coordination with the CT-CM, which i) should facilitate providing scientific advice on the clinical research needs in preparedness and response to public health emergencies, and ii) promote a coordinated approach to the national and EU funding of identified clinical research needs.

The partnership should strengthen the European Research Area by supporting excellence in innovative research and capacity building, widening the engagement of countries not yet involved. As a demonstration of its added value, the partnership should be able to attract the engagement of a broad range of stakeholders beyond European health authorities and research funders, such as private and philanthropic actors and innovators.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 212 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

The relevant European research infrastructures 213  in the area of health should be exploited for available services, expertise and digital tools for dataset creation, standardisation, data discovery, secure access, management, visualization, harmonization, analysis and other functions as appropriate.

When defining calls for proposals in the context of jointly funded transnational research, the partnership should consider sex and identity-related differences. If relevant, it also needs to consider the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, to produce meaningful and significant effects enhancing the societal impact of the related research activities. The support and involvement of citizens and civil society should be considered.

The partnership will consolidate a suitable health research data ecosystem aligned with the European Health Data Space (EHDS) 214 , and the European Open Science Cloud (EOSC) 215  supporting the harmonisation and standardisation as well as the federated access of FAIR 216 research data in the context of pandemic preparedness and response. The partnership’s work should comply with the appropriate ethical, regulatory and legal frameworks, and should ensure the timely translation of research outcomes into effective clinical and public health policy and innovation.

HORIZON-HLTH-2026-01-DISEASE-15: Scaling up innovation in cardiovascular health

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.90 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 1.90 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, legal entities established in the United States of America may exceptionally participate as a beneficiary or affiliated entity, and are eligible to receive Union funding.

Coordinators of projects must be legal entities established in an EU Member State or Associated Country.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 217 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Healthcare providers, policymakers and researchers benefit from an improved knowledge base and collaboration on the key challenges and gaps on cardiovascular health research and a conceptual framework to develop a roadmap for research and innovation is established.

2.Health systems gain improved and standardised evidence to better prevent, diagnose or treat cardiovascular diseases (CVDs) and associated comorbidities, based on the research results on prediction, early detection, screening practices and diagnostic methods and tools, including via personalised and digital approaches.

3.Medical and non-medical health professionals and technology developers have an increased knowledge, awareness and capacity to uptake and deliver effective and innovative approaches for risk prediction, early detection, screening and health management strategies, such as Virtual Human Twins (VHT) 218 or Artificial Intelligence (AI)-based applications. This involves supporting, strategic foresight, improving health literacy and cross-sectoral knowledge exchange and collaboration to drive innovation in personalised prevention and cardiovascular risk prediction.

4.Healthcare providers and policymakers have an improved knowledge base to inform future strategies for early detection and prevention of CVDs, with specific attention to women and vulnerable groups, through research on personalised risk prediction approaches that consider multiple and interacting risk factors (e.g. genetic predisposition, environmental pollutants, diet, lifestyle habits, multimorbidity, sex and gender).

Scope: CVDs are the main cause of death in the EU, with over 1.7 million deaths annually, costing about EUR 282 billion, or 11% of the healthcare budget 219 . With projections showing a rise in CVD prevalence and mortality by 2050 due to an aging population, the Commission is preparing a comprehensive EU Cardiovascular Health (CVH) plan 220 to support Member States in their efforts to reduce the burden of CVDs. The proposal is expected to support prevention, early detection, including via digital and personalised approaches.

Applicants should take stock of research and innovation results to identify gaps and set up a plan for a Strategic Research and Innovation Agenda (SRIA) on CVDs, with the final aim of leveraging research and innovation results to improve risk prediction, early detection and screening practices for CVDs and associated comorbidities, especially obesity and diabetes, across the EU and Associated Countries. This initiative addresses the pressing need to translate existing innovations and promising research results into implementable protocols that enhance prevention, diagnosis, and health outcomes for diverse populations. By fostering collaboration and integrating digital tools and methods, proposals will support the future EU CVH plan, building and aligning with future and ongoing activities, including the European VHT Initiative, the 1+Million Genomes Initiative 221 , Tech Foresight/Horizon scanning activities 222 and actions funded under the EU4Health Programme (2021-2027) 223 and the Digital Europe Programme 224 .

Proposals should include all the following activities:

1.Conduct a comprehensive review at national, EU, and international levels of existing cardiovascular research and innovative healthcare solutions, potentially linked with associated comorbidities, to identify gaps and areas where future integration into health systems can have the greatest impact. The mapping should build upon existing EU-level reviews and pay particular attention to sex- and gender-related gaps, including under-representation in studies and differences in risk, diagnosis, and treatment. Such insights will inform subsequent policy actions and implementation initiatives under other funding programmes.

2.Create a detailed report outlining the barriers to effective personalised prediction, screening and prevention in cardiovascular health, providing recommendations to overcome these challenges.

3.Develop a SRIA on CVDs and associated comorbidities aiming to improve personalised prevention, prediction and screening and to inform research funders and stakeholders, including relevant EU and national initiatives. The agenda will include stakeholder validation and adoption pathways. Support the development of personalised prevention and care pathways and the role of digital interventions, based on genomics, VHTs and AI-driven methods in line with the European Health Data Space (EHDS) 225 Regulation, to enhance precision in early detection and health management. Where applicable, the mapping of existing practices such as biomarkers for diagnosis, monitoring in patients, and stratification of patient groups should be considered.

4.Integrate sex and gender-related variables, age, racial or ethnic origin 226 , socio-economic, lifestyle and behavioural factors, genetic predisposition into research design, data collection and analysis, to ensure inclusive and generalisable findings enhancing the effectiveness of screening, diagnostic, and prevention strategies across diverse population groups.

5.Organise high-impact, targeted events with clear objectives to promote a multi-sectorial approach, fostering collaboration among healthcare providers, researchers, civil society, patients' organisations, and policymakers

6.Work with health experts to develop the capacities for implementing standardised screening protocols and methods.

7.Develop a comprehensive dissemination strategy and stakeholder engagement plan to share findings and promote the results, utilising online platforms and social media to reach a broad audience. Complement with long-term engagement mechanisms such as policy briefings or partnerships with EU-level dissemination networks.

The applicants should ensure adequate involvement across the project lifespan of all relevant stakeholders and value chain actors including industry, healthcare professionals, scientists, patients’ associations to ensure performance and sustainability and maximise the final impact.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts and institutions, in order to meaningfully enhance the societal impact of the related research activities.

HORIZON-HLTH-2027-02-DISEASE-01-two-stage: Innovative healthcare interventions for non-communicable diseases

Call: Cluster 1 - Health (Two stage - 2027)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 7.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 63.80 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

For the first stage, the thresholds for each criterion will be 4 (Excellence) and 4 (Impact). The overall threshold applying to the sum of the two individual scores will be set at a level that ensures the total requested budget of proposals admitted to stage 2 is as close as possible to three times the available budget, and not less than two and a half times the available budget.

For the second stage, the thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 227 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Researchers, developers and clinical practitioners have access to state-of-the-art knowledge, data, technologies, tools, methods, best practices, and trainings to develop innovative healthcare interventions aimed at reducing burden of the following specific Non-Communicable Diseases (NCDs): cardiovascular diseases, diabetes, chronic respiratory diseases or chronic kidney diseases.

2.Scientific and clinical communities can use innovative healthcare interventions to generate meaningful advances in clinical practice and care for patients with NCDs following validation in late-stage clinical trials.

3.Scientific and clinical communities make wide use of relevant databases and/or integrate them with existing infrastructures for storage and sharing of collected data according to FAIR 228 principles, thereby encouraging further use of the data.

4.Policymakers, scientific and clinical communities, developers, patient organisations, regulators, and other relevant bodies are informed of the research advances made and the requirements for a widespread implementation of the innovative therapeutic interventions and complementary approaches.

5.Patients and caregivers are constructively engaged with the research, ensuring that their needs are catered for, with the aim of tangibly benefitting from the interventions.

Scope: NCDs represent over 80% of the disease burden in Europe and the leading cause of avoidable premature deaths. Innovative and effective healthcare interventions are required to provide treatment and disease management solutions and assure best quality of care for patients suffering from NCDs when prevention strategies have failed.

Proposals should address all the following aspects:

1.Perform rigorous early stage 229 clinical trial(s) to validate novel or refined healthcare interventions 230 for treatment and/or disease management solutions for patients suffering from the following specific NCDs: cardiovascular diseases, diabetes, chronic respiratory diseases or chronic kidney diseases 231 . Whenever relevant, existing co- and multimorbidities should be addressed in the trial design.

2.Clinical trial(s) should be supported by completed proof-of-concept 232 of clinical safety and efficacy.

3.Both preclinical research and the draft clinical trial protocol should be completed at the time of submission of the proposal. Proposals should also demonstrate evidence of preliminary consultations with ethics and regulatory authorities at the time of submission.

4.A sound feasibility assessment, including an appropriate patient selection and realistic recruitment plans, justified by publications or preliminary results should be provided.

5.Take into account sex and gender differences in all relevant aspects throughout the research process, and consider stratification criteria such as age, disability, racial or ethnic origin 233 , socio-economic status, genetic and epigenetic variations, etc., where relevant.

6.Use and/or develop technologies, including digital ones (e.g. (generative) Artificial Intelligence, wearable technologies) to help implement and monitor the long-term efficacy of the intervention(s), as well as manage the disease and/or monitor their progression (e.g. with unobtrusive technologies suitable for patient monitoring at home and in real-world conditions), whilst also ensuring they are bias-free, inclusive, and ethically sound. Hardware and software should be interoperable in line with internationally accepted standards 234 . The use of virtual human twins 235 could also be considered, where relevant.

7.Exploit existing data, health data infrastructures 236 , biobanks, registries and/or cohorts, together with the generation of new data that should be managed in line with the FAIR principles and contribute to emerging research infrastructures established in the framework of the European Health Data Space (EHDS) 237 , when relevant.

8.Advance research by leveraging already existing and emerging state-of-the-art research infrastructures as well as results stemming from EU-supported research projects, where applicable.

9.Engage all relevant stakeholders (especially patients and patients’ representatives, caregivers, clinicians, counsellors, regulators, etc.) to design end-user optimised interventions.

10.Engage with national public health authorities and regulators to ensure a robust development pathway and further uptake of the intervention.

11.Present a thorough health-economic assessment and Real-World Data (RWD) 238 analysis to enhance sustainability and scalability of novel interventions.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 239 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

All projects funded under this topic are encouraged to participate in networking and joint activities, as appropriate 240 and explore potential synergies with projects funded under the EU4Health Programme (2021-2027) 241  in the area of NCDs.

Applicants invited to the second stage should provide details of their clinical studies 242 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2027-01-DISEASE-05: Development of novel small molecule antiviral therapeutics for pathogens with epidemic potential

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 9.00 and 11.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 44.20 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced project portfolio covering the viruses/groups of viruses targeted in this topic 243 , grants will be awarded (within available budget) to proposals not only in order of ranking but at least also to those proposals that are the highest ranked within different viruses/groups of viruses targeted, provided that the proposals attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.The scientific and clinical communities have a better understanding of and access to experimental antivirals for the prevention and treatment of emerging or re-emerging viral infections, as well as for further clinical investigation.

2.Candidate antiviral therapies are available to treat patients for emerging and re-emerging viral infections, increasing therapeutic options for clinical deployment in case of an epidemic or pandemic.

Scope: Infectious diseases remain a major threat to health and health security in the EU and globally. Viral disease emergence is already being accelerated by climate change, and thus a proactive approach to the development of antiviral prophylactics and therapeutics in preparedness for future infectious disease outbreaks is needed. The availability of antivirals targeting conserved viral or host mechanisms would provide a critical preparedness measure against future health threats caused by (re)emerging infectious disease epidemics or pandemics, due to infectious disease epidemics or pandemics.

This topic contributes to strengthening the Research and Innovation ecosystem within the EU and supports the implementation of the European Medical Countermeasures Strategy 244 .

Antibodies and antibody derived proteins are excluded from the scope of this topic.

Applicants should explicitly state in their proposal which of the following viruses/groups of viruses is targeted and the proposed work should address only this specific virus/group of viruses. The proposed work should aim to advance the development of novel or existing antiviral candidates targeting exclusively one of the following viruses/groups of viruses:

1.Junin mammarenavirus and/or Lassa mammarenavirus

2.Tick-borne encephalitis virus and/or Japanese encephalitis virus

3.Andes virus and/or Hantaan virus and/or Sin Nombre virus

4.Hendra virus

5.Enterovirus D68

6.Venezuelan equine encephalitis virus

Identifying a specific virus/group of viruses does not preclude the exploration of these antiviral candidates' effects on other viruses/groups of viruses. Proposals should thus aim to diversify and accelerate the global prophylactic and therapeutic research and development portfolio for emerging and re-emerging viral infections, and to strengthen the leading role of the EU in prophylactic and therapeutic research and development.

Proposals should address some of the following research areas:

1.Discovery and selection of candidate antivirals with consideration for intra-family and/or variant-transcending potential.

2.Optimisation of selected candidates to improve potency, selectivity, pharmacokinetics, and developability, using Structure-Activity Relationship (SAR) studies or equivalent methodologies.

3.In-vitro characterisation of antiviral activity, mechanism of action, and, where appropriate, resistance potential across multiple viruses or strains.

4.In-vivo tests in at least one animal model or, if available in human organoid or organotypic models, to demonstrate the protective function of the antiviral candidates and deemed sufficient for moving to first clinical trials.

5.If requested by regulators as pre-requisite for clinical studies, in-vivo tests in a non-human primate model.

6.Production of batches of the most promising antiviral candidates according to the Good Manufacturing Practices (GMP) 245 of the most promising therapeutics solution.

7.First in human clinical safety studies demonstrating a clear regulatory pathway for market authorisation. Attention should be paid to critical biological and social factors such as sex, age, ethnicity and disability.

Participation of third countries where viruses addressed in the proposal are endemic or where outbreaks have occurred or are ongoing is encouraged.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 246 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

All projects funded under this topic are expected to engage with regulatory bodies in a timely manner to ensure adequacy of the actions from a regulatory point of view.

Proposals should advance research by leveraging already existing and emerging state-of-the-art research infrastructures 247 such as those having contributed to the services developed under the ISIDORe project 248 .

The projects funded under this topic should synergise with projects funded by the co-funded European Partnership for Pandemic Preparedness 249 .

Applicants should provide details of their clinical studies 250 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2027-01-DISEASE-06: Development of monoclonal antibodies to prevent and treat infections from Flaviviruses

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 9.00 and 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 37.30 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced project portfolio covering the Flaviviruses targeted in this topic 251 , grants will be awarded (within available budget) to proposals not only in order of ranking but at least also to those proposals that are the highest ranked within different Flaviviruses targeted, provided that the proposals attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.The scientific and clinical communities have a better understanding of and access to experimental monoclonal antibodies for the prevention and treatment of emerging or re-emerging viral infections, as well as for further clinical investigation.

2.Candidate monoclonal antibody therapies are available to treat patients for emerging and re-emerging viral infections, increasing therapeutic options for clinical deployment in case of an epidemic or pandemic.

Scope: Infectious diseases remain a major threat to health and health security in the EU and globally. Viral disease emergence is already being accelerated by climate change, and thus a proactive approach to the development of antiviral prophylactics and therapeutics in preparedness for future infectious disease outbreaks is needed. The capacity to produce antibodies that can target new variants and rapidly increase production would serve as an essential preparedness strategy against future health threats, whether from infectious disease epidemics or pandemics.

This topic contributes to strengthening the Research and Innovation ecosystem within the EU and supports the implementation of the European Medical Countermeasures Strategy 252 .

Applicants should explicitly state in their proposal which of the following Flaviviruses is targeted and the proposed work should address only this specific Flavivirus. The proposed work should aim to advance the development of existing prophylactic and therapeutic monoclonal antibody candidates targeting exclusively one of the following Flaviviriuses:

1.Dengue Virus

2.Tick-borne Encephalitis Virus

3.Japanese Encephalitis Virus

4.West Nile Fever Virus

5.Yellow Fever Virus

6.Zika Virus

Proposals should focus on antibodies produced or derived from a single cell clone through recombinant expression, such as B-cell derived antibodies, hybridoma derived antibodies and nanobodies.

Proposals should thus aim to diversify and accelerate the global prophylactic and therapeutic research and development portfolio for emerging and re-emerging viral infections, and to strengthen the leading role of the EU in prophylactic and therapeutic research and development.

Proposals should address all the following research areas:

1.If necessary, finalisation of the in-vitro characterisation of existing monoclonal antibody candidates with regard to target specificity, epitope recognised, and their ability to impair or inactivate viral functions.

2.In-vivo tests in at least one animal model or, if available in humanised immune system animal models, to demonstrate the protective function of the monoclonal antibodies deemed sufficient for moving to first clinical trials.

3.If requested by regulators as pre-requisite for clinical studies, in-vivo tests in a non-human primate model.

4.Evaluation of Antibody-Dependent Enhancement (ADE) risk where scientifically relevant.

5.Production of batches of the most promising antibody candidates according to the Good Manufacturing Practices (GMP) 253 .

6.First in human clinical safety studies demonstrating a clear regulatory pathway for market authorisation. Attention should be paid to critical biological and social factors such as sex, age, ethnicity and disability.

Participation of third countries where viruses addressed in the proposal are endemic or where outbreaks have occurred or are ongoing is encouraged.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 254 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

All projects funded under this topic are expected to engage with regulatory bodies in a timely manner to ensure adequacy of the actions from a regulatory point of view.

Proposals should advance research by leveraging already existing and emerging state-of-the-art research infrastructures 255 such as those having contributed to the services developed under the ISIDORe project 256 .

Applicants should provide details of their clinical studies 257 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2027-01-DISEASE-07: Development of monoclonal antibodies to prevent and treat infections from Filo-, Nairo-, Phenui-, Picorna- and Toga viruses

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 9.00 and 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 37.30 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced project portfolio covering the viruses targeted in this topic 258 , grants will be awarded (within available budget) to proposals not only in order of ranking but at least also to those proposals that are the highest ranked within different viruses targeted, provided that the proposals attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.The scientific and clinical communities have a better understanding of and access to experimental monoclonal antibodies for the prevention and treatment of emerging or re-emerging viral infections, as well as for further clinical investigation.

2.Candidate monoclonal antibody therapies are available to treat patients for emerging and re-emerging viral infections, increasing therapeutic options for clinical deployment in case of an epidemic or pandemic.

Scope: Infectious diseases remain a major threat to health and health security in the EU and globally. Viral disease emergence is already being accelerated by climate change, and thus a proactive approach to the development of antiviral prophylactics and therapeutics in preparedness for future infectious disease outbreaks is needed. The capacity to produce antibodies that can target new variants and rapidly increase production would serve as an essential preparedness strategy against future health threats, whether from infectious disease epidemics or pandemics.

This topic contributes to strengthening the Research and Innovation ecosystem within the EU and supports the implementation of the European Medical Countermeasures Strategy 259 .

Applicants should explicitly state in their proposal which of the following viruses is targeted and the proposed work should address only this specific virus. The proposed work should aim to advance the development of existing prophylactic and therapeutic monoclonal antibody candidates targeting exclusively one of the following viruses:

1.Ebola Virus

2.Marburg Virus

3.Crimean-Congo Hemorrhagic Fever Virus

4.Rift Valley Fever Virus

5.Enterovirus D68

6.Chikungunya Virus

Proposals should focus on antibodies produced or derived from a single cell clone through recombinant expression, such as B-cell derived antibodies, hybridoma derived antibodies and nanobodies.

Proposals should thus aim to diversify and accelerate the global prophylactic and therapeutic research and development portfolio for emerging and re-emerging viral infections, and to strengthen the leading role of the EU in prophylactic and therapeutic research and development.

Proposals should address all the following research areas:

1.If necessary, finalisation of the in-vitro characterisation of existing monoclonal antibody candidates with regard to target specificity, epitope recognised, and their ability to impair or inactivate viral functions.

2.In-vivo tests in at least one animal model or, if available in humanised immune system animal models, to demonstrate the protective function of the monoclonal antibodies deemed sufficient for moving to first clinical trials.

3.If requested by regulators as pre-requisite for clinical studies, in-vivo tests in a non-human primate model.

4.Evaluation of Antibody-Dependent Enhancement (ADE) risk where scientifically relevant.

5.Production of batches of the most promising antibody candidates according to the Good Manufacturing Practices (GMP) 260 .

6.First in human clinical safety studies demonstrating a clear regulatory pathway for market authorisation. Attention should be paid to critical biological and social factors such as sex, age, ethnicity and disability.

Participation of third countries where viruses addressed in the proposal are endemic or where outbreaks have occurred or are ongoing is encouraged.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 261 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

All projects funded under this topic are expected to engage with regulatory bodies in a timely manner to ensure adequacy of the actions from a regulatory point of view.

Proposals should advance research by leveraging already existing and emerging state-of-the-art research infrastructures 262 such as those having contributed to the services developed under the ISIDORe project 263 .

Applicants should provide details of their clinical studies 264 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2027-01-DISEASE-08: Development of innovative antimicrobials against pathogens resistant to antimicrobials

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 8.00 and 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 44.20 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced project portfolio covering the pathogens targeted in this topic 265 , grants will be awarded (within available budget) to proposals not only in order of ranking but at least also to those proposals that are the highest ranked within different pathogens targeted, provided that the proposals attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.The scientific and clinical communities have a better understanding of and access to new and innovative products for the treatment of antimicrobial resistant bacteria and fungi, as well as for further clinical investigation.

2.Candidate therapies are available to treat patients for antimicrobial resistant bacteria and fungi, increasing therapeutic options for clinical deployment in the fight against Antimicrobial Resistance (AMR).

Scope: The rapid rise of AMR presents a formidable threat to public health, challenging our ability to treat infections that were once easily managed with standard antimicrobials. As pathogens continually adapt and develop resistance to existing drugs, the efficacy of these treatments diminishes, leading to more severe and prolonged illnesses, increased healthcare costs and productivity losses, and higher mortality rates. This escalating crisis underscores an urgent need for viable therapeutic alternatives required to reduce the burden of diseases caused by antibiotic resistance. Innovative solutions are crucial to maintaining effective disease management and safeguarding public health.

Proposals should pursue the development of innovative and effective antibacterial and antifungal agents, including antibody-based therapies, which meet at least one of the four World Health Organization (WHO) innovation criteria 266 , namely: i) new chemical class, ii) new target, iii) new mode of action and iv) no evidence of cross-resistance.

This topic contributes to strengthening the Research and Innovation ecosystem within the EU and supports the implementation of the European Medical Countermeasures Strategy 267 and the forthcoming Critical Medicines Act 268 .

Proposals under this topic should not pursue the development of phage-therapies.

Applicants should explicitly state in their proposal which of the following pathogens is targeted and the proposed work should address only this specific pathogen. The proposed work should pursue the development of existing therapeutic candidates targeting exclusively one of the following pathogens:

1.Carbapenem resistant Acinetobacter baumanii (CRAB)

2.Carbapenem-resistant Enterobacterales (CRE) and third-generation cephalosporin-resistant Enterobacterales (C3GRE)

3.Carbapenem resistant Pseudomonas aeruginosa

4.Methicillin-Resistant Staphylococcus aureus (MRSA)

5.(Drug)-resistant Aspergillus fumigatus

6.(Drug)-resistant Candida spp 

Identifying a specific pathogen does not preclude the exploration of these candidates' effects on other bacteria or fungi. Proposals should thus aim to accelerate testing of novel candidates in human trials, diversify and accelerate the global prophylactic and therapeutic research and development portfolio for AMR bacterial and fungal infections, and to strengthen the leading role of the EU in prophylactic and therapeutic research and development.

Proposals should address all the following areas:

1.If necessary, finalisation of in-vivo tests in at least one animal model or, if available in humanised immune system animal models, to demonstrate the protective function of the therapeutics deemed sufficient for moving to first clinical trials.

2.If requested by regulators as pre-requisite for clinical studies, in-vivo tests in a non-human primate model.

3.Production of batches of the most promising antimicrobials candidates according to the Good Manufacturing Practices (GMP) 269 .

4.In human clinical safety and efficacy studies, demonstrating a clear regulatory pathway for market authorisation. Attention should be paid to critical biological and social factors such as sex, age, ethnicity, disability and vulnerability.

Participation of third countries where AMR bacteria and fungi in the proposal are endemic or where outbreaks have occurred or are ongoing is encouraged.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 270 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

All projects funded under this topic are expected to engage with regulatory bodies in a timely manner to ensure adequacy of the actions from a regulatory point of view.

Proposals should advance research by leveraging already existing and emerging state-of-the-art research initiatives such as the co-funded European Partnership on One Health Anti-Microbial Resistance (EUP OHAMR) 271 .

Applicants should provide details of their clinical studies 272 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2027-01-DISEASE-10: Prevention and management of chronic non-communicable diseases in children and young people (GACD)

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 11.80 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 273 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to some of the following expected outcomes:

1.Researchers, healthcare practitioners and providers in low- and middle-income countries (LMICs) 274 and/or those in high-income countries (HICs) serving disadvantaged populations have access to improved insights and evidence on how to equitably promote the early prevention, risk reduction, and timely diagnosis of Non-Communicable Diseases (NCDs) in children and/or young people.

2.Policymakers, public health managers and authorities, parents and their children, and young adults have access to evidence and recommendations for national programmes and policies to improve quality of life in children and/or young people and extend healthy life expectancy.

3.Researchers, clinicians, policymakers, public health managers and authorities have an improved understanding how to effectively adapt and/or scale up interventions for prevention and management of chronic NCDs in children and/or young people at local, regional, and national levels.

4.Communities, parents and their children, young adults, local stakeholders and authorities are fully engaged in implementing and taking up interventions that tackle NCDs in children and/or young people.

Scope: The Commission is a member of the Global Alliance for Chronic Diseases (GACD) 275 . The GACD specifically addresses NCDs and supports implementation research 276 to improve health outcomes. This topic is launched in concertation with the other GACD members (international funding agencies) and aligned with the 12th GACD call.

Chronic NCDs that begin in childhood have an impact on both quality of life and life expectancy. Onset of many NCDs diseases occurs at younger ages in LMICs, and this is further accompanied by a longer duration of disease and a higher rate of complications, including multimorbidity. The conditions in which people are born, grow and live (the social determinants of health) including access to good nutrition, education, housing, and healthcare are major contributors to health and ill health 277 .

Up to 70% of preventable adult deaths from NCDs are linked to risk factors originating in childhood and adolescence 278 , and interventions that can successfully control or prevent chronic disease in young people can dramatically improve health outcomes later in life. Childhood and adolescence are critical periods, when behaviours associated with NCD risk are adopted including tobacco use, alcohol use, substance abuse, unhealthy diets and sedentary lifestyles and children and young people are often targeted by commercial marketing of unhealthy products.

The aim of this topic is to fund implementation research, exploring strategies, evidence-based program and policy interventions across prevention, diagnosis, screening and management of chronic NCDs, centred on the critical life stages spanning early childhood to young adulthood (1-24 years of age) living in LMICs, and/or underserved populations in HICs.

In this regard, proposals focused on implementation research should explore implementation strategies on evidence-based interventions, adaptations of interventions and tailored interventions, or initiatives including (though not limited to) those focussed on one or more of the following:

1.Policy evaluation to tackle childhood- and/or youth-relevant social, economic, political, structural or commercial determinants of chronic NCD conditions.

2.Prevention of NCDs using children and/or young people targeted implementation strategies (e.g. educational strategies, vaccination strategies, promotion of behavioural and lifestyle changes).

3.Screening and diagnosis of NCDs (or risk factors) in children and/or young people (in particular use of digital tools).

4.Cost effective and patient-centred management of NCDs in children and/or young people (including access to medicines and equipment; integrated care pathways; continuity of care for adolescents with existing non-communicable diseases who "age out" of paediatrics, caregiver health and support, citizen science approaches).

Multiple interventions focus on prevention of NCDs in children and young people, yet relatively few have focussed on strategies for management of chronic conditions in these critical life stages, and a limited number of studies have been carried out to study implementation of these in LMIC contexts or with underserved communities. In this instance it would be anticipated that proposals should explore implementation strategies using the appropriate hybrid design study incorporating effectiveness and implementation research outcomes. Therefore, it may be important to undertake formative research as a part of the proposal to support readiness for implementation.

The proposed implementation research should be focused on one or more evidence-based interventions (or complex interventions), providing existing evidence of the intervention’s effectiveness, cost-effectiveness, sustainability, scalability and potential for long-term health and other impacts (and in what context this evidence has been generated).

Applicants should provide rationale and explore the implementation of proposed intervention(s) for a selected study population(s) based in one or more LMICs, and/or underserved populations experiencing health disparities, including Indigenous populations, in HICs, considering the unique social, political, economic, and cultural context(s) in which the study will take place 279 . Applicants should justify why any adaptation will not compromise the known effectiveness of the selected intervention(s).

Proposals should address all the following implementation research activities 280 :

1.Clearly describe the implementation research methodology, including the statistical design.

2.Have an appropriate strategy for measuring implementation research outcomes and real-world effectiveness outcomes and indicators.

3.Specifically address issues of equitable implementation to ensure interventions reach the populations that need them the most.

4.Engage an appropriately expert and skilled research team which can ensure a suitable multidisciplinary approach and that demonstrates equitable partnership and shared leadership between HIC-LMIC, and/or non-Indigenous-Indigenous members of the project team and external stakeholders through a clear governance strategy.

5.Provide a stakeholder engagement strategy with evidence of support/engagement from key stakeholders for delivering the intervention and a pathway to sustain the proposed intervention (if proven effective) after the funding from the GACD grant ends.

6.Provide opportunities for NCD-focused implementation research capacity building for early career researchers and team members from lower resourced environments, such as LMICs or disadvantaged communities.

7.Ensure meaningful involvement of early career team members, including at least one early career member as a co-investigator.

The study population may include children and/or young people in the general population, with one or more existing NCDs, those currently without NCDs, or a combination of any of the above. Applicants may propose implementation research focused on interventions that are implemented at the individual, family, community (e.g. work or school), population, and/or structural level. With regard to NCDs, applicants are encouraged to explore any chronic non-communicable condition (or combination of conditions), including mental health disorders, autoimmune conditions, musculoskeletal conditions, neurological disorders and sleep disorders and/or any risk factor (or combination of risk factors). Additionally, whenever relevant, applicants are also encouraged to take a life course approach, adapting interventions for particular life stages with the goal of promoting life-long health.

Proposals should use an appropriate implementation research design and framework 281 , before and after studies, and additional implementation science classifications of study designs (e.g. hybrid designs 282 ), noting that applicants are not limited to any particular design.

Proposals would be expected to generate evidence that is of direct relevance to policymakers, communities and practitioners. Proposed work should identify and engage all key stakeholders necessary and relevant to the development, undertaking and knowledge translation phases of the project, including meaningful collaboration with young people themselves (and their families). Proposals should also consider using co-development and co-design approaches, involving policymakers, local authorities, community groups, educators, healthcare providers, and other individuals or organisations necessary to the delivery and sustainability of the study outcomes. Project partners should be engaged from the beginning to contribute to the sustainability of the intervention after the end of project. Proposals should demonstrate sustainability of the strategy, beyond the lifespan of the project.

Poverty, discrimination based on sex, racial or ethnic origin 283 , religion or belief, disability, age, and other inequities are directly associated with reduced potential for equitable access to quality care. Proposals should consider relevant determinants of health (e.g. social, structural, commercial, economic) and discuss their potential impact on the effective implementation of the intervention(s). If there is a focus on a particular population (e.g. gender, racial or ethnic origin 284 , etc.), then the reason for this should be justified.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

All projects funded under this topic are strongly encouraged to participate in networking and joint activities, including internationally, as appropriate. These activities could, for example, involve the participation in joint workshops, the Annual Scientific Meetings of the GACD, the exchange of knowledge, the development and adoption of best practices, or joint communication activities. Therefore, proposals are expected to include a budget for such activities and may consider covering the costs of any other potential joint activities without the prerequisite to detail concrete joint activities at this stage. The details of these joint activities will be defined during the grant agreement preparation phase.

Applicants should provide details of their clinical studies 285 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2027-02-DISEASE-14-two-stage: Clinical trials for advancing innovative interventions for neurodegenerative diseases

Call: Cluster 1 - Health (Two stage - 2027)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 39.30 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

For the first stage, the thresholds for each criterion will be 4 (Excellence) and 4 (Impact). The overall threshold applying to the sum of the two individual scores will be set at a level that ensures the total requested budget of proposals admitted to stage 2 is as close as possible to four times the available budget, and not less than three and a half times the available budget.

For the second stage, the thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Tackling diseases and reducing disease burden”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.The scientific and clinical communities make effective use of state-of-the-art knowledge, data, technologies, tools, methods, best practices, and trainings to underpin and complement the development of innovative interventions aimed at more effective treatments for neurodegenerative diseases.

2.The scientific and clinical communities benefit from the exchange of data, knowledge and best practices, thereby strengthening their collaboration in the EU, the Associated Countries and beyond.

3.The scientific and clinical communities make wide use of relevant databases and/or integrate them with existing infrastructures for storage and sharing of collected data according to FAIR 286 principles, thereby encouraging further use of the data.

4.Policymakers, funders, scientific and clinical communities, patient organisations, regulators, and other relevant bodies are informed of the research advances made and the requirements for a widespread implementation of the innovative therapeutic interventions and complementary approaches.

5.Patients and caregivers are constructively engaged with the research, ensuring that their needs are catered for, with the aim of tangibly benefitting from the interventions.

Scope: Neurodegenerative diseases are a high burden for patients, caregivers, health systems and society. Given the limitations with current therapeutic solutions, including that they primarily address symptoms rather than underlying causes and can have serious side effects, together with the increasing prevalence of neurodegenerative diseases in an aging population, there is a huge need to develop more innovative, safer and more effective therapeutic solutions for these diseases. To further enhance their safety and effectiveness, the therapeutic solution based on an active substance should be combined/complemented with another multidisciplinary approach (e.g. lifestyle changes, cognitive training, rehabilitation therapies). Together this innovative intervention should lead to an improved quality of life and reduce the societal impact of these diseases.

Rare neurodegenerative diseases are excluded 287 .

Proposals should address most of the following aspects:

1.Perform rigorous early-stage 288 clinical trials into the safety and efficacy of the innovative interventions and their mode of administration, ensuring adequate cohorts/sample sizes with adequate representation of the patient population, including in terms of age, sex and ethnicity.

2.Through the clinical trials and to the extent possible of additional studies, gain further insight into the potentially novel mechanism(s) of action of the innovative therapies and complementary approaches. This could entail analyses of imaging (e.g. MRI, ultrasound, nuclear imaging), as well as physiological, molecular, biochemical or omics signatures revealing potential perturbations prior to the intervention and recovery/improvement thereafter, and it could lead to the development of surrogate endpoints. This insight should open the path to more personalised interventions and approaches.

3.Use and/or develop technologies, including digital ones (e.g. (generative) Artificial Intelligence - AI 289 , wearable technologies) to help implement and monitor the long-term efficacy of the intervention(s), as well as manage the disorder and/or monitor their progression (e.g. with unobtrusive technologies suitable for patient monitoring at home and in real-world conditions), whilst also ensuring they are bias-free, inclusive, and ethically sound.

4.Utilise existing data, biobanks, registries and/or cohorts, together with the generation of new data that should be managed in line with the FAIR principles.

5.Engage all relevant stakeholders (especially patients and patients’ representatives for the disease, caregivers, clinicians, counsellors, regulators, etc.) to design end-user optimised interventions, applying gender-sensitive and intersectional approaches.

6.Advance research by leveraging already existing and emerging state-of-the-art research infrastructures (e.g. EuroBioImaging 290 , European Genomic Data Infrastructure 291 , ECRIN 292 , EATRIS 293 , EBRAINS 294 , BBMRI 295 , etc.), as well as results stemming from EU-supported research projects, where applicable 296 .

7.Engage with national public health authorities and regulators to ensure a robust development pathway and further uptake of the intervention.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 297 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

Funded projects should liaise with the future co-funded European Partnership for Brain Health 298 (covered by topic HORIZON-HLTH-2025-02-DISEASE-01: “European Partnership for Brain Health”) once launched.

The topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

All projects funded under this topic are strongly encouraged to participate in networking and joint activities, as appropriate. Therefore, proposals should include a budget for the attendance to regular joint meetings and may consider covering the costs of any other potential joint activities without the prerequisite to detail concrete joint activities at this stage. The details of these joint activities will be defined during the grant agreement preparation phase.

Applicants should provide details of their clinical studies 299 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

Destination - Ensuring equal access to innovative, sustainable, and high-quality healthcare

Topics under this destination are directed towards the Key Strategic Orientation 2 “The Digital transition” and Key Strategic Orientation 3 “A more resilient, competitive, inclusive, and democratic Europe” of Horizon Europe’s strategic plan 2025-2027 300 .

Research and Innovation supported under this destination should contribute to the following expected impact, set out in the strategic plan impact summary for the Health Cluster: “healthcare systems provide equal access to innovative, sustainable and high-quality healthcare thanks to the development and uptake of safe, cost-effective and people-centred solutions. This is to be accompanied by management models focusing on population health, health systems resilience, and health equity and patient safety, and also improved evidence-informed health policies”.

Health systems are affected by limitations in sustainability and resilience, and face inequalities in access to high-quality and acceptable healthcare services. Health systems need to become more effective, efficient, accessible, fiscally and environmentally sustainable, and resilient in order to cope with public health emergencies, support healthcare workforce, adapt to environmental challenges like climate change, and contribute to social justice and cohesion. The transformation and modernisation of health systems will remain an important challenge for many years to come, but it also holds a significant opportunity to generate evidence, leverage existing and emerging solutions, implement digital and data-driven innovation and develop more accessible, cost-effective, flexible and equitable health systems.

Research and Innovation under this destination should aim to support the transformation of healthcare systems ensuring fair and inclusive access to high-quality, acceptable, sustainable healthcare for all. Funded activities will focus on developing innovative, practical, scalable and financially sound solutions, that improve governance, provide decision-makers with new evidence, tools, and technologies, and ensure long-term fiscal, environmental and climate sustainability. A patient-centred approach should be adopted, improving patients’ health outcomes, empowering patients, fostering active dialogue among stakeholders (e.g. citizens, patients, caregivers, healthcare providers), and encouraging social innovation. Research and Innovation actions should prioritise supporting healthcare professionals and providers, ensuring they have the resources and tools needed to meet the diverse needs and preferences of citizens. Research and Innovation should facilitate scalable and transferable solutions that can be applied across different healthcare systems and national, regional, and local contexts. This should include generating knowledge that supports the transfer of solutions between countries, including measures to address health inequalities. Research and Innovation activities under this destination will contribute to, among other things, the European Care Strategy 301 , the digital transformation of health and care in the EU 302 , the European Pillar of Social Rights 303 304 , the EU strategy on adaptation to climate 305 , the Pharmaceutical Strategy for Europe 306 , the European Health Data Space (EHDS) 307 , the Strategy for European Life Sciences 308 and the European Green Deal 309 . They align with the Commission's Political Guidelines for 2024-2029 310 , which include efforts to complete the European Health Union by promoting access for all to high-quality and affordable healthcare, fostering a resilient and innovative health ecosystem, and strengthening the competitiveness of the European Union 311 .

In this Work Programme part, the focus of this destination will be on public procurement of innovative solutions for integrated or personalised care, aiming to develop and test solutions that improve access to and provision of healthcare. It will also support personalised medicine approaches to reduce adverse drug reactions due to the administration of multiple medication, and research to identify and address low-value care in health and care systems, improving healthcare outcomes, efficiency, and fiscal sustainability.

To increase the impact of EU investments under Horizon Europe, the Commission encourages and supports cooperation among EU-funded projects to foster cross-fertilisation and synergies. This includes networking, joint activities such as workshops, knowledge exchange, best practices development, and joint communication activities. Synergies can be explored not only between projects funded under the same topic, but also between projects funded under other topics, Clusters or Pillars of Horizon Europe. For instance, collaborations may arise between projects related to European health research infrastructures (under Pillar I), the EIC 312 strategic challenges on health (under Pillar III), or across the Clusters of Pillar II such as Cluster “Culture, Creativity and Inclusive Society” focusing e.g. on the long-term sustainability of public health systems (e.g. economic and organisational models and measures for cost effectiveness and fiscal sustainability), or Cluster “Digital, Industry and Space” focusing on the digitalisation of the health sector, including the use of Artificial Intelligence (AI).

The Commission aims to foster synergies between Horizon Europe and other EU programmes. To this end, applicants are encouraged to explore the funding opportunities available through the EU4Health Programme (2021-2027) 313 , the EU's public health programme, as a means of capitalising on potential collaborations and maximising impact.

Expected impacts:

Proposals for topics under this destination should set out a credible pathway to contributing to ensuring access to innovative, sustainable, inclusive and high-quality healthcare, and more specifically to one or several of the following impacts:

1.Health and social care services and systems have improved governance mechanisms, making them more effective, efficient, accessible, resilient, trusted and sustainable, from fiscal, organisational and environmental perspectives. This includes shifting from hospital-centred to community-based, people-centred and integrated healthcare structures, embedding technological innovations and prioritising health promotion and disease prevention and management.

2.Healthcare providers are trained and equipped with the skills and competences needed for future healthcare systems that are modernised, digitally transformed and equipped with safe innovative tools, technologies and digital solutions for healthcare. This will involve better patient management, improved patient engagement and health outcomes, reorganised workflows, and improved resource management.

3.Citizens play a key role in managing their own healthcare, informal carers (including unpaid carers) are fully supported (e.g. by preventing overburdening and economic stress) and the specific needs of groups in a vulnerable situation are recognised and addressed. This includes improved access to healthcare services, financial risk protection, timely access to quality healthcare services including essential medicines and vaccines.

4.Health policy and systems adopt a holistic approach -considering individuals, communities, organisations, society- in evaluating health outcomes, public health interventions, healthcare organisation, and decision-making. They benefit from evidence based, scalable and transferable healthcare solutions (e.g. between countries and healthcare settings) including for addressing health inequalities and ensuring environmental and climate sustainability in the health sector.

The actions resulting from the topics under this destination will also create strong opportunities for synergies with actions stemming from the EU4Health programme, in particular contributing to the goals under the general objective “protecting people in the Union from serious cross-border threats to health” and specific objective 4 “to strengthen health systems, their resilience and resource efficiency”.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in the Annex B of the General Annexes of this Work Programme.

The protection of European communication networks has been identified as an important security interest of the Union and its Member States. Entities that are assessed as high-risk suppliers 314 of mobile network communication equipment (and any entities they own or control) are not eligible to participate as beneficiaries, affiliated entities and associated partners to topics identified as “subject to restrictions for the protection of European communication networks”. Please refer to the Annex B of the General Annexes of this Work Programme for further details.

Proposals are invited against the following topic(s):

HORIZON-HLTH-2026-01-CARE-01: Public procurement of innovative solutions for improving citizens' access to healthcare through integrated or personalised approaches

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 24.50 million.

Type of Action

Public Procurement of Innovative Solutions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

The specific conditions for actions with PCP/PPI procurements in section H of the General Annexes apply to grants funded under this topic.

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries may provide financial support to third parties to ensure the deployment and impact of the project outcomes. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000.

The specific conditions are described in General Annex H.

PPI procurement costs are eligible.

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Ensuring equal access to innovative, sustainable, and high-quality healthcare”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to several of the following expected outcomes:

1.Patients and their carers, health authorities and health professionals will benefit from the deployment of innovative solutions, designed around actual clinical needs, that facilitate identification, integration or coordination of care, allowing for personalised, more accessible, inclusive and higher quality of health and care.

2.Patients will benefit from personalised approaches, improved care experiences and health outcomes or are more engaged in their care and better equipped to make informed decisions on their health, in collaboration with health professionals.

3.Health professionals will be better equipped with, and thus benefit from, improved means for diagnosis, care delivery and/or coordination, with multi-disciplinary approaches and closer patient engagement, thanks to new technologies.

4.Health systems will improve their accessibility, coordination mechanisms, effectiveness, inclusivity and resilience, thanks to innovative solutions, with a better use of resources, thus stimulating organisational innovation, cultural transformation within hospitals, and European-level collaboration.

Scope: Public Procurement of Innovative Solutions (PPI) 315 can boost the wider market uptake of high impact innovations in health systems, while enhancing the tools available to providers and improving access to healthcare for citizens. This supports enhancement of social rights 316 and the European economic competitiveness by providing business opportunities and thus incentives to innovate. By acting as early adopters of innovative solutions, procurers can open up new growth markets for the European industry and small and medium-sized enterprises (SMEs) 317 . Joint/collaborative demand-driven initiatives can help create economies of scale and facilitate the wider adoption of innovations in the health sector for the benefits of patients in need.

PPI actions target consortia of procurers with a similar need that want to procure together the deployment of innovative solutions for supporting integration of care or diagnostics for personalised medicine. This topic does not provide direct funding to developers, industry or research organisations to perform research and development. They will be able to respond to the call for tenders launched by consortia of procurers funded under this topic.

Proposals should specify which segment of the patient population they target, the specific organisational and/or technological innovations to be procured, and why the proposed innovative solutions would be fit for purpose adhering, when relevant, to the principles of integrated care 318 or personalised medicine 319 .

Examples of target groups that could be covered by this action are: patients at risk of vulnerability such as children and older/frail people with complex needs for health and social care; people with multi-morbidities or non-communicable diseases of high burden; people with both physical and mental health conditions; people living with rare diseases or cancer; persons with disabilities; other groups of patients in need of highly integrated and coordinated care. Proposals should pay attention to how gender and intersectional factors (e.g. caregiving responsibilities, work-related health disparities etc.) affect healthcare access and outcomes.

Proposals should demonstrate, with qualitative and quantitative indicators, how they contribute to the above expected outcomes, clearly describe the application of the principles of integrated care and personalised medicine in the deployed solutions, when relevant. This would also include embedding the innovation in the existing health systems, addressing gaps and avoiding overlaps, while fostering change management across organisations, professions and sectors.

Solutions envisaged within this action are for example digital solutions 320 , including Artificial Intelligence (AI) elements, to facilitate delivery of integrated care across hospitals, primary care, Long-Term Care (LTC) facilities and home settings, or technologies that improve routine diagnosis and lead to personalised medicine approach with the health and care setting.

The actions should target first deployment of innovative solutions across different health and care jurisdictions in Europe by engaging public and/or private procurers from each participating country (at national, regional or local level) that have deployment responsibilities and budget control in the provision of health and care services. Procurers will specify, purchase and deploy solutions addressing their relevant and shared unmet needs, while engaging together in a supply and demand side dialogue. Proposals should be based on clearly identified user needs and well-structured deployment plans, explaining how the procurement of the innovative solutions will contribute to the expected outcomes and improve current practice. In addition, cost-effectiveness analyses as well as estimates of the wider economic impact are highly desirable.

Activities covered should include cooperation with policymakers to reinforce national/regional policy frameworks and policies, to raise awareness, for technical assistance and/or capacity building beyond the project, to mainstream PPI implementation and remove obstacles to introduce innovative solutions to the market.

A wide variety of settings are potentially relevant for the implementation of such innovative solutions, for example primary healthcare settings, hospitals, specialised centres, long-term care facilities and home settings. The involvement of end-users (including for analysing the impact of the deployed solutions on health professionals and patients across the care continuum) and the use of cross-sectorial approaches are necessary. When relevant, linkage with ongoing work at national level for the implementation of the European Health Data Space (EHDS) 321 is encouraged. Proposals are encouraged to consider, where relevant, the data, expertise and services offered by European research infrastructures 322 in the health domain.

Transfer and adaptation of solutions and/or interventions from other sectors to healthcare is possible. The topic is open both to innovations bringing improvements mainly based on one specific solution/technology field, as well as to innovations delivering end-to-end solutions that need combinations of different types of innovative elements. Proposals are strongly encouraged to build upon past work and build synergies with ongoing EU-funded initiatives, for example the Joint Actions JADECARE 323 and Xt-EHR 324 , the project MyHealth@Myhands 325 and the three co-funded European Partnerships on Transforming Health and Care Systems 326 , on Personalised Medicine 327 and on Rare Diseases 328 , as well as with actions supported under the Technical Support Instrument and the Cohesion Policy Funds.

HORIZON-HLTH-2026-01-CARE-03: Identifying and addressing low-value care in health and care systems

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 38.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Ensuring equal access to innovative, sustainable, and high-quality healthcare”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Healthcare providers and policymakers make use of evidence-based indicators and methodologies to identify low-value care 329 practices, as well as opportunities for improvement and tools to monitor such improvements.

2.Healthcare professionals are equipped with the knowledge and tools to implement guidelines for reducing or discontinuing low-value care activities and maintaining effective and patient-centred practices that ensure quality of care.

3.Patients and citizens benefit from more effective healthcare, by understanding and endorsing measures that reduce low-value care, recognising the potential to achieve higher-quality healthcare and better health outcomes overall.

4.Health and care systems benefit from a reduction of low-value care practices, which enables enhanced patient safety and quality of care, while contributing to their efficiency as well as fiscal and environmental sustainability.

5.Healthcare organisations can, by identifying low-value care practices, reallocate valuable healthcare resources to other areas of need.

Scope: Low-value care, as defined in the footnote, can have widespread negative consequences for patients, caregivers, healthcare professionals, the health and care system, and the broader environment. A 2017 OECD report 330 estimated that “wasteful healthcare spending is common” and that “up to one-fifth of healthcare spending could be redirected towards better uses”. Low-value care represents a significant challenge, contributing to waste, costs, misuse of resources, and inefficiencies. Addressing low-value care can free up and allow reallocation of valuable healthcare resources to other areas of need, thereby maximising health outcomes, improving health and care systems resilience, and reducing their environmental impact. In this context, a recent report 331 by the Expert Group on Health Systems Performance Assessment (HSPA) 332 establishes the methodological basis and metrics to identify, measure and reduce low-value care.

Research activities under this topic should adopt a patient-centred approach that considers the needs and preferences of patients and citizens. They should promote socially acceptable solutions, taking into account relevant ethical, social and legal aspects and foster dialogue and collaboration between policymakers, healthcare providers, healthcare professionals, and patients/citizens. Proposals should engage citizens and civil society organisations in the development of their actions to ensure acceptability of solutions. By doing so the projects will contribute to better use of healthcare resources -including time and personnel- in ways that significantly improve patient outcomes and alleviate the increasing burden on healthcare professionals and health systems. Implementation research and multidisciplinary approaches should be considered to foster adoption and ensure effective interventions and long-term sustainability.

Proposed activities may 333 include clinical studies 334 to provide evidence on the value of any interventions or processes and, therefore, facilitate justified removal of any type of low value care. Proposed activities may also include data models, digital and artificial intelligence-based analysis, models and/or tools to identify and/or address low-value care. Proposed activities may examine the design and impact of healthcare payment systems, that could unintentionally incentivise low-value care and evaluate alternative financing models that better align incentives with patient outcomes and high-value care. Proposed activities may also facilitate or implement collaboration among registries (disease registries such as cancer registries, primary healthcare visits registries, prescription and drug purchase registries, reimbursement and medical devices registries, screening databases, socio-economic and census databases, etc.) across regions or countries, to enable or improve the assessment and comparison of different levels of care and their value to patients. Additionally, activities that facilitate learning and best practice transfers between countries or regions may also be considered as element of the proposal (for instance, to leverage best practice-sharing initiatives from international platforms such as the Knowledge Hub of the co-funded European Partnership on Transforming Health and Care Systems 335 or any other relevant European or global initiatives). Additionally, proposals may include or support international comparisons of low-value care practices and strategies for their reduction across countries, if and where deemed valuable.

Research actions should address all the following objectives:

1.Develop a deeper understanding of how low-value care can be identified and measured throughout the healthcare process, including testing related indicators and producing evidence-based methodologies that enable the pursuit of improved efficiency and quality of care.

2.Identify instances of overuse, misuse, underuse and unwarranted variation in specific healthcare contexts across different stages of the healthcare process. This analysis should provide actionable insights for policymakers, healthcare providers and healthcare professionals to evaluate the potential of possible strategies for reducing low-value care, allowing for more informed decision-making and improved care practices.

3.Develop and/or pilot innovative strategies for effective reduction of low-value care in specific settings across the care pathway. These pilots should demonstrate scalability and transferability across diverse health and care systems in Europe.

Proposals should consider how gender norms and roles influence utilisation patterns, ensuring that strategies to reduce low-value care do not inadvertently exacerbate existing gender and social inequalities in healthcare access and outcomes. In addition, attention should be paid to intersectional factors that may further affect healthcare access and outcomes. If handling data and indicators, sex- and gender-disaggregated data should be collected and analysed, incorporating intersectional factors where feasible.

Proposals should consider the work and output of any EU level initiatives (e.g. the Expert Group on Health Systems Performance Assessment, the co-funded European Partnership on Transforming Health and Care Systems, relevant projects or Joint Actions funded under the EU4Health Programme (2021-2027) 336 and under EU Research & Innovation Framework Programmes, etc.) or other international initiatives (e.g. the 2017 OECD report mentioned above) in this area.

Applicants envisaging 337 to include clinical studies 338 should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

HORIZON-HLTH-2026-04-CARE-04: Enhancing and enlarging the European Partnership on Personalised Medicine (EP PerMEd) (Top-up)

Call: Partnerships in Health (2026/3)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 9.80 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 9.80 million.

Type of Action

Programme Co-fund Action

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The proposal must be submitted by the coordinator of the consortium funded under topic HORIZON-HLTH-2023-CARE-08-01: “European Partnership on Personalised Medicine”. This eligibility condition is without prejudice to the possibility to include additional partners.

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding. Because the US contribution will be considered for the calculation of the EU contribution to the partnership, the concerned consortium of research funders from eligible EU Members States and Associated Countries must expressly agree to this participation.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The evaluation will take into account the existing context and the scope of the initial evaluation as relevant, and related obligations enshrined in the grant agreement.

If the proposal is successful, the next stage of the procedure will be grant agreement amendment preparations.

If the outcome of amendment preparations is an award decision, the coordinator of the consortium funded under topic HORIZON-HLTH-2023-CARE-08-01: “European Partnership on Personalised Medicine” will be invited to submit an amendment to the grant agreement, on behalf of the beneficiaries.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

This action is intended to be implemented in the form of an amendment of the grant agreement concluded pursuant to Article 24(2) of the Horizon Europe Regulation.

For the additional activities covered by this action:

1.The funding rate is 30% of the eligible costs.

2.Beneficiaries may provide financial support to third parties (FSTP). The support to third parties can only be provided in the form of grants. As a co-funded European Partnership, providing financial support to third parties (FSTP) is a core activity of this action in order to achieve its objectives. Consequently, the EUR 60 000 threshold laid down in Article 207 of Financial Regulation (EU, Euratom) 2024/2509 does not apply. The maximum amount of FSTP that may be awarded to any single third party for the duration of the partnership is set at EUR 10.00 million. This ceiling is justified by the fact that FSTP is a primary activity of this action, by its expected duration of 7-10 years (exceeding a standard project lifespan), and by the extensive experience gained under predecessor partnerships. This ceiling is also justified by the fact that personalised medicine being at the forefront of medical approaches, requires the use of state-of-the-art technologies and tailored clinical trials which are usually expensive. However, if the objectives of the action would otherwise be impossible or overly difficult (and duly justified in the proposal) the maximum amount may be higher.

3.The starting date of the grant awarded under this topic may be as of the submission date of the application. Applicants must justify the need for a retroactive starting date in their application. Costs incurred from the starting date of the action may be considered eligible (and will be reflected in the entry into force date of the amendment to the grant agreement).

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Total indicative budget

The total indicative budget for the duration of the co-funded partnership is EUR 109.8 million.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Ensuring equal access to innovative, sustainable, and high-quality healthcare”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.European countries and regions, along with international partners, are engaged in enhanced collaborative research efforts for the development of innovative personalised medicine approaches regarding prevention, diagnosis and treatment.

2.Healthcare authorities, policymakers and other stakeholders develop evidence-based strategies and policies for the uptake of personalised medicine in national or regional healthcare systems.

3.Health industries, policymakers and other stakeholders have access to efficient measures and investments to allow swift transfer of research and innovation into market.

4.Health industries and other stakeholders can accelerate the uptake of personalised medicine through the adoption of innovative business models.

5.Healthcare authorities, policymakers and other stakeholders use improved knowledge and understanding of the health and costs benefits of personalised medicine to optimise healthcare and make healthcare systems more sustainable.

6.Healthcare providers and professionals improve health outcomes, prevent diseases and maintain population health through the implementation of personalised medicine.

7.Stronger and highly connected local/regional ecosystems of stakeholders, including innovators, are in place and facilitate the uptake of successful innovations in personalised medicine, thus improving healthcare outcomes and strengthening European competitiveness.

8.Citizens, patients and healthcare professionals have a better knowledge of personalised medicine and are better involved in its implementation.

9.Stakeholders cooperate better and establish a network of national and regional knowledge hubs for personalised medicine.

Scope: This topic targets an action under Article 24(2) HE Regulation aiming to add additional activities to existing grant agreements, together with additional partners that would deliver on those activities. The award of a grant to continue the partnership in accordance with this call should be based on a proposal submitted by the coordinator of the consortium funded under topic HORIZON-HLTH-2023-CARE-08-01: “European Partnership on Personalised Medicine” and the additional activities and additional partners to be funded by the grant should be subject to an evaluation. Taking into account that the present action is a continuation of the topic HORIZON-HLTH-2023-CARE-08-01: “European Partnership on Personalised Medicine” and foresees an amendment to an existing grant agreement, the proposal should present the additional activities (including additional partners) to be covered by the award primarily in terms of grant agreement revisions. Partners from countries recently associated to Horizon Europe from 2024 onwards (2024 included) are particularly welcome. The existing action, the “European Partnership for Personalised Medicine” (EP PerMed) can only reasonably be enhanced and enlarged on the basis of the existing consortium 339 , as the co-funded framework established cannot simply be replaced without significant disruption, given the top-quality, long-term expertise and wide coverage of the beneficiaries comprising this consortium.

The additional activities to be performed by applicants under this topic should consist of several of the following:

1.Organisation of activities or tools according to their expertise and interests, e.g.:

1.Personalised Medicine (PM) Innovation related activities and tools, business and entrepreneur relations and support, case studies and guides.

2.PM public health and social care, people’s engagement, activities to support health system’s ability to turn scientific discoveries into new or improved treatments and services, support the scientific community to tackle complex health and social care challenges, international outreach.

3.PM and diversity, underrepresented populations, gender aspects, health data and knowledge mobilisation activities, PM and rare diseases.

4.PM related genomics, expert and societal exchange on genomics, opportunities by genomics for innovations and economic growth.

2.Contribution to the design and implementation of the specific topics and features of the Transnational Joint Calls as of 2026 to which new partners will contribute national commitments.

3.Specific, tailored contributions to other EP PerMed calls such as: Fast Track, Venture Creation Programme, Networking, Twinning calls, Call for surveys, Education calls, etc.

4.Organisation of specific EP PerMed events, such as in-situ visits (Work Package 5 - WP5), summer schools (WP3/4).

5.Contribution to the development and dissemination of strategic documents in additional geographical areas, for example the Strategic Research and Innovation Agenda (SRIA) updates.

6.Development and implementation of other new PM tailored activities within the related WPs.

HORIZON-HLTH-2027-01-CARE-02: Personalised approaches to reduce risks from Adverse Drug Reactions due to administration of multiple medications

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 8.00 and 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 38.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Ensuring equal access to innovative, sustainable, and high-quality healthcare”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Patients benefit from decreased incidence of Adverse Drug Reactions (ADRs) caused by the administration of multiple medications (three or more medicinal products 340 ) and enhanced health outcomes by ensuring safer and more effective use of medication.

2.Healthcare professionals can adopt adverse drug reactions prevention and reduction strategies to integrate genetic and other biomarker information into clinical decision-making to optimise the use of medication, especially in situations of comorbidities.

3.Healthcare systems benefit from cost savings thanks to reduced hospital admissions and other costs associated with ADRs related to the intake of multiple medicines.

4.Clinical and regulatory guidelines and policies for medication management in case of multiple medications can be revised supported by robust evidence.

5.Educational programs for healthcare providers and patients benefit from improved awareness and management of polypharmacy and ADRs.

Scope: While medicinal products contribute considerably to the health of EU citizens, they can also have adverse reactions. It is estimated that around 5% of all hospital deaths are due to an adverse drug reaction. On average, 16% of hospitalised older 341 patients experience significant ADRs, varying in severity and mostly preventable, with commonly prescribed drug classes (such as diuretics, anti-bacterials, antithrombotic agents, analgesics, antineoplastics, etc.) accounting for most ADRs 342 . Overall, ADRs increase morbidity, mortality, hospitalisations, and healthcare costs.

ADRs from multiple medications contribute significantly to healthcare costs due to increased hospitalisations and treatments, making this an area of focus to achieve cost efficiency.

Initial failure to recognise ADRs can generate inappropriate prescription cascades, in which the side effects of drugs are misdiagnosed as symptoms of new problems, resulting in further prescriptions and further side effects that tend to accumulate, confusing and complicating the diagnostic while aggravating the evolution. Therefore, there is a distinct need for research to help identify and prevent such prescription cascades, possibly by maximising the use of technology, as well as to improve multiple drug management in order to reduce patient harm. Furthermore, it is also possible that aside from the ADRs specific to individual drugs taken in combination, new ADRs can emerge as results from the drug combinations themselves.

Research activities under this topic should make use of the constantly improving health technologies and data analytics that provide new opportunities to address these issues more effectively, by better integrating medication management into healthcare practices, including into Electronic Health Records (EHR) and decision support systems.

Identifying and validating relevant biomarkers for better patient stratification can contribute to significantly decreasing the risk of adverse drug reactions. Biomarkers can also help to detect adverse drug reactions early before occurrence of clinical symptoms and enable early countermeasures. Generating knowledge on the interaction and complexity of biochemical pathways can improve the understanding of patients' response to ADRs and thus provide better tailored treatments and early responses to adverse reactions.

For this purpose, any biomedical strategy that allows a better stratification of patients to identify drug response patterns in well-defined patient groups could be used, including in-vitro or in-silico models for adverse drug reactions, imaging biomarkers, drug-drug/drug-gene/drug-food interactions, therapeutic dose reduction and pharmaco-exposomics, nutrition and beverage interference, smoking, vaping, pollution etc. De-escalation studies in view of improving multiple drug management can be also considered. Proposals should be sufficiently robust to examine differences across various populations, and also consider sex difference in drug reactions.

The further use of results generated by the projects funded under this topic should be ensured through data sharing with the relevant stakeholders and the European Medicines Agency (EMA), in view of possible adoption of deprescribing or adjusted-prescribing guidelines by relevant authorities at EU and national levels.

Where applicable, applicants are strongly encouraged to follow all relevant guidelines in the relevant scientific fields, including but not limited to:

1.Joint EMA/Heads of Medicines Agencies (HMA)/EC Workshop recommendations on pharmacogenomics in medicines regulation and on implementation into clinical practice 343 .

2.Pharmaceutical development of medicines for use in the older population, Scientific guideline from the EMA 344 .

3.Guidelines from the Clinical Pharmacogenetics Implementation Consortium (‘CPIC guidelines’) 345 .

Proposals funded under this topic should address all the following aspects:

1.Leverage the role of pharmacogenomics, pharmacokinetics and pharmacodynamics in predicting and preventing adverse drug reactions in situations of multiple medications (three or more drugs administered concomitantly), and propose personalised medicine approaches, such as targeted therapies and biomarker-driven treatment strategies, to reduce the rate of adverse drug reactions and limit multiple medications.

2.Maximise the use of technology, such as electronic health records, artificial intelligence and clinical decision support systems, to support safe medication use and prevent adverse drug reactions.

3.Address the ethical, regulatory, and implementation challenges associated with integrating personalised medicine into clinical practice to address adverse drug reactions due to the administration of multiple medications.

4.Generate evidence on the clinical utility and cost-effectiveness of treatment guided by pharmacogenomics and other relevant biomarkers-based approach, for single drugs and for combinations of drugs.

5.Develop and implement strategies, including regulatory science approaches, for efficient integration of project results into daily healthcare.

6.Align with similar work in other EU-funded projects or partnerships, such as the co-funded European Partnership for Personalised Medicine 346 , the co-funded European Partnership on Transforming Health and Care System 347 etc. while avoiding any potential overlaps.

The participation of start-ups, micro, small and medium-sized enterprises (SMEs) 348 is encouraged with the aim of strengthening their scientific and technological foundations, enhancing their innovation potential, and exploring possibilities for commercial exploitation.

Applicants should provide details of their clinical studies 349 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

Destination - Developing and using new tools, technologies and digital solutions for a healthy society

Topics under this destination are directed towards the Key Strategic Orientation 2 “The Digital Transition” and Key Strategic Orientation 3 “A More Resilient, Competitive, Inclusive, and Democratic Europe” of Horizon Europe’s strategic plan 2025-2027 350 .

Research and Innovation supported under this destination should contribute to the following expected impact, set out in the strategic plan impact summary for the Health Cluster: “Health technologies, data, new tools, and digital solutions are applied effectively thanks to their inclusive, ethically sound, secure and sustainable delivery, integration and deployment in health policies and in health and care systems.”

The Health Cluster will continue to drive the development and adoption of innovative technologies and digital solutions to improve healthcare and health systems. This will ensure that the EU remains at the forefront of breakthrough health and medical technologies and can achieve open strategic autonomy in essential medical supplies and digital innovations.

In line with the Commission's Political Guidelines for 2024-2029 351 , this destination will support research and innovation in tools and technologies strengthening the competitiveness of European health industry and reinforcing EU autonomy. This effort will contribute to the completion of the European Health Union which aims to enhance the resilience of healthcare systems, facilitate access to innovative and affordable healthcare solutions, and ensure that all citizens have access to high-quality, equitable, inclusive and sustainable healthcare.

The development and use of innovative tools and technologies for biomedical research are the basis for prevention, early diagnosis, efficacious therapy and patient monitoring, essential components of efficient healthcare. These include enabling technologies, not least innovative biotechnological approaches, and emerging technologies like synthetic biology, digital tools including those based on Machine-Learning/Artificial Intelligence (ML/AI) and other data-driven approaches which will enable the development of more personalised medicine. Hence the combination of innovative tools, high-quality health data (incl. Real-World Data - RWD 352 ), digital technologies, modelling and AI tools holds great potential not only for advancing biomedical Research and Innovation but for developing health technologies that improve healthcare.

However, the implementation of these tools and technologies faces specific barriers such as scalability, regulatory frameworks and public acceptance and trust. To overcome these challenges cross-sectoral cooperation among stakeholders including researchers, regulatory bodies, policymakers, industry, healthcare providers and patients, is necessary. This collaboration will facilitate the design and development of innovative health products and services, tailored to specific population groups, ultimately improving patient outcomes and reducing health inequalities.

By taking a comprehensive and inclusive approach, this destination will prioritise the development of novel tools and technologies that address key considerations such as the rights of the individual, safety, effectiveness, appropriateness, accessibility, comparative value-added and fiscal sustainability while also ensuring ethical, legal and regulatory compliance.

In this Work Programme part, Destination “Developing and using new tools, technologies and digital solutions for a healthy society” is driven mainly by three key Commission policies, the “Biotechnology and Biomanufacturing Communication” 353 the “Artificial Intelligence Strategy” 354 and the “Strategy for European Life Sciences” 355 and focuses on developing and applying innovative technologies to improve human health and healthcare systems. The topics under this destination cover efforts to develop AI based predictive biomarkers for disease prognosis and treatment response, advancing bio-printing of living cells for regenerative medicine, and integrating New Approach Methodologies (NAMs) to advance biomedical research, as well as developing virtual human twins for integrated clinical decision support.

To increase the impact of EU investments under Horizon Europe, the Commission encourages cooperation between EU-funded projects to enable cross-fertilisation and other synergies. For example, this cooperation could take the form of networking, to joint activities, such as the participation in joint workshops, exchange of knowledge, development and adoption of best practices, or joint communication activities. Opportunities for such activities and potential synergies exist between projects funded under the same topic but also between other projects funded under different topics, Clusters or Pillars of Horizon Europe. Specifically, this could involve projects related to European health research infrastructures (under Pillar I of Horizon Europe), the EIC 356 strategic challenges on health (under Pillar III of Horizon Europe) or with projects on themes that cut across the Clusters of Pillar II such as with Cluster “Digital, Industry and Space” on digitalisation of the health sector or key enabling technologies.

Expected Impacts:

Proposals for topics under this destination should set out a credible pathway towards the development and use of new tools, technologies and digital solutions for a healthy society, and more specifically to one or several of the following impacts:

1.Europe’s scientific and technological expertise and know-how, its capabilities for innovation in new tools, technologies and digital solutions, and its ability to take-up, scale-up and integrate innovation in healthcare is world-class.

2.Citizens benefit from targeted and faster research resulting in safer, more sustainable, efficient, cost-effective, accessible and affordable tools, technologies and digital solutions for improved (personalised) disease prevention, diagnosis, treatment and monitoring for better patient outcome and wellbeing, in particular through increasingly shared health resources (interoperable data, infrastructure, expertise, citizen/patient driven co-creation) 357 .

3.The EU gains high visibility and leadership in terms of health technology development, including through international cooperation.

4.The burden of diseases in the EU and worldwide is reduced through the development and integration of innovative diagnostic and therapeutic approaches, personalised medicine approaches, digital and other people-centred solutions for healthcare.

5.Both the productivity of health Research and Innovation, and the quality and outcome of healthcare is improved thanks to the use of health data and innovative analytical tools, such as AI supported decision-making, in a secure, ethical and inclusive manner, respecting individual integrity and underpinned with public acceptance and trust.

6.Citizens trust and support the opportunities offered by innovative technologies for healthcare, based on expected health outcomes and potential risks involved.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in the Annex B of the General Annexes of this Work Programme.

The protection of European communication networks has been identified as an important security interest of the Union and its Member States. Entities that are assessed as high-risk suppliers 358 of mobile network communication equipment (and any entities they own or control) are not eligible to participate as beneficiaries, affiliated entities and associated partners to topics identified as “subject to restrictions for the protection of European communication networks”. Please refer to the Annex B of the General Annexes of this Work Programme for further details.

Proposals are invited against the following topic(s):

HORIZON-HLTH-2026-01-TOOL-03: Integrating New Approach Methodologies (NAMs) to advance biomedical research and regulatory testing

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 49.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

In order to maximise synergies and increase the impact of the projects, all proposals selected for funding from this topic will form a cluster and be required to participate in common networking and joint activities (and in determining modalities for their implementation and the specific responsibilities of projects). These activities will be included in a dedicated work package, having sufficient budget allocated to it (around 2% of the total requested budget). Depending on the scope of proposals selected for funding, these activities may include:

1.Attendance of regular joint meetings (e.g. common kick-off meeting and annual meetings).

2.Periodic report of joint activities (delivered at each reporting period).

3.Common dissemination and communication activities (which may include, for example: a common dissemination and communication strategy, web portal and visual identity, brochure, newsletters).

4.Common Data Management Strategy and Common Policy Strategy (including joint policy briefs).

5.Thematic workshops/trainings on issues of common interest.

6.Working groups on topics of common interest (e.g. data management and exchange, communication and dissemination, science-policy link, scientific synergies).

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 359 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to several of the following expected outcomes:

1.Researchers are in possession of improved human-relevant New Approach Methodologies (NAMs) platforms that capture the genetic, phenotypic, age-related, immune, microbiome, and environmental exposure variability of the human population. These innovations support more equitable healthcare solutions and personalised treatment strategies across diverse life stages.

2.Industry gets access to platforms that allow a faster pace of innovation for the development of more cost-effective targeted therapeutic interventions and improvement of the safety assessment of chemicals, other medicinal products, and medical devices.

3.Patients benefit from innovative platforms and strategies that improve prediction, prevention and treatment of diseases, in particular through enhanced understanding of disease pathways and mechanisms.

4.The general population is better protected through a safer environment, as these platforms enhance the detection and mitigation of risks posed by chemicals and other potentially harmful substances.

5.Regulatory bodies gain confidence and trust in NAMs, supporting their integration into product development, risk assessment, and approval processes.

6.Fewer live animals are used in biomedical research and regulatory testing.

Scope: This topic aims to support the ongoing paradigm shift in biomedical research and safety assessment of chemical compounds by fully integrating NAMs across the entire research and regulatory spectrum, from basic discovery phase to clinical application, and regulatory testing of medicinal products and medical devices, and/or industrial and environmental chemicals.

NAMs include a wide range of innovative and human-relevant technologies such as in-vitro or human ex-vivo assays, organoids, Organ-on-Chip (OoC) systems, human tissue models, induced Pluripotent Stem Cell (iPSC) applications, virtual twin tools, in-silico methods, and Artificial Intelligence (AI)-driven modelling.

Although the Commission and several Member States have supported the development of NAMs for over two decades, primarily in the context of chemical risk assessment, regulatory uptake remains limited. There is a need to address this situation by delivering validated NAMs solutions that can be adopted by industry and accepted by the regulators for the safety assessment of chemicals. In parallel, there is a growing readiness to expand the development and application of NAMs across the entire biomedical research spectrum, from early discovery through to clinical translation and regulatory testing of medicinal products and medical devices.

Proposals should bring together stakeholders from academia, health-related infrastructures, SMEs 360 , industry, and regulators to develop new NAMs platforms or improve existing ones that could be used for biomedical applications and/or regulatory testing. For biomedical applications, these platforms should enhance disease modelling precision, especially in areas where current animal models are of limited human relevance, and where NAMs could effectively complement or replace animal studies. For proposals addressing regulatory use, in particular the safety assessment of chemicals, other medicinal products and medical devices, the intended context(s) of use should be clearly defined, with validation strategies and methodologies aligned with current OECD and/or European Medicines Agency (EMA) guidance. Early, proactive, and sustained engagement with regulators should also be demonstrated.

Proposals should develop or optimise scalable and reproducible platforms based on one or more of the following:

1.Advanced in-vitro assays.

2.iPSC-based models, organoid or complex OoC systems derived from patients and/or healthy donors.

3.Human tissues that closely replicate physiological and pathological conditions.

In order to enable real-time monitoring of physiological responses, proposals should consider integration of embedded sensors. They should also address biological diversity, reflecting variations in genetics, phenotype, age, immune status, and microbiome across the population.

Moreover, proposals may incorporate one or both of the following complementary approaches to enhance predictive power and clinical relevance:

1.AI-driven predictive modelling trained on high-quality, curated, bias-minimised datasets to predict outcomes of biomedical interventions, or risk assessment.

2.Virtual twin technology to simulate disease progression, responses to interventions, and support the optimisation of clinical trials.

To maximise scientific impact, interoperability, and reuse, all data generated should comply with FAIR 361 principles. Proposals should describe how data will be curated, standardised, and shared within or linked to the European Health Data Space (EHDS) 362 or other repositories, and/or relevant ESFRI 363 research infrastructures.

In order to optimise synergies and increase the impact of the projects, all proposals selected for funding from this topic will form a cluster and be required to participate in common networking and joint activities.

Proposals should consider involving the European Commission's Joint Research Centre (JRC), including its EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) 364 , to take advantage of its expertise and relevant activities in bridging research and application communities and facilitating uptake of NAMs in biomedical research and regulatory testing. In that respect, the JRC should collaborate with any successful proposal and this collaboration should be established after the proposal’s approval.

Applicants envisaging to include clinical studies 365 should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

HORIZON-HLTH-2026-01-TOOL-05: Pilot actions for follow-on funding: Leveraging EU-funded collaborative research in regenerative medicine

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 29.50 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The proposals must be based on results generated within a prior multi-beneficiary project funded under Horizon 2020 or Horizon Europe Framework Programme. This project must have been completed maximum 3 years before the submission deadline.

Applicants must explicitly state in their proposal the prior multi-beneficiary project concerned. Projects funded under Marie Sklodowska-Curie Actions are not considered eligible. Projects funded under co-funded European Partnerships or ERANETs are considered eligible. Ongoing projects 366 are not considered eligible.

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 367 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.The overall competitiveness of the EU biotechnology sector is strengthened through the further development of closer-to-deployment health innovations.

2.The EU benefits from greater impact of the EU’s Research and Innovation (R&I) Framework Programmes through successful leveraging of previous EU funding in the field of regenerative medicine.

3.EU innovators secure further funding to finalise the last stages of development.

4.Patients benefit faster from solutions that improve their health and wellbeing.

Scope: R&I is essential for economic growth and boosting the competitiveness of the EU's life sciences sector. Through the Horizon 2020 and Horizon Europe Framework Programmes, the EU has supported projects that significantly impact our health by fostering scientific discoveries and developing new solutions. Transformational health innovations, such as mRNA vaccines, highlight the importance of collaboration among businesses, research institutions, and healthcare providers. Furthermore, sustained funding throughout the entire value chain is crucial for maximising impact and ensuring more products reach patients faster. The main aim of this topic is to pilot a follow-on funding mechanism, supporting the stepwise development of biotech innovations through collaboration, resulting from previously supported EU R&I actions in the field of health. This topic contributes to strengthening the R&I ecosystem within the EU and supports the implementation of the “Strategy for European Life Sciences” 368 . Given the importance of biotechnology as a critical technology 369 , this topic aims to ensure that promising research results are efficiently taken further along the value chain, speeding the time to market or patient through stepwise funding and increasing the EU’s competitiveness. The chosen area of focus is regenerative medicine as it has the potential to heal or replace tissues and organs damaged by age, disease, or trauma, as well as to normalise congenital defects. Proposals should focus on prototyping, demonstrating and validating health innovations from TRL 5, moving beyond early-stage research to clinical development, testing, or eventual large-scale manufacturing. The previously funded EU research on which the proposal is build should be applicable to the field of regenerative medicine and should have clear exploitation potential and/or socio-economic benefits for the patients.

Applicants are expected to:

1.Demonstrate in their proposal that the health product, therapy or service, has been successfully validated at preclinical level in the prior EU funded project and provide justification of the innovation potential with qualitative and quantitative data (e.g. publications, patent/trademark/design applications, spin-out/start-up track record, regulatory procedures, venture capital pitches, funds raised etc).

2.Justify the proposed composition of the consortium and explain how this differs from the previous grant, and demonstrate how the health product, therapy or service to be developed further qualifies as regenerative medicine.

3.Demonstrate adequate protection of the idea or Intellectual Property Rights or ensure freedom to operate until full deployment.

4.Have a clear vision on the intended pathway to patients and/or route to market, including regulatory compliance. This includes defining specific milestones together with concrete and verifiable Key Performance Indicators (KPIs) to assess progress towards the market or healthcare settings.

5.Identify the target patient group(s) (how many patients to be treated during the project and the potential patient population that could benefit) and product development milestones including a financial plan (for each milestone).

In the case of innovations with commercial potential, proposals should present the investor and market readiness towards commercialisation and deployment (market research, value proposition, business case and business model, prospects for growth, intellectual property protection, competitor analysis etc.) as well as aspects of regulation, certification and standardisation and reimbursement.

In the case of innovations with evidenced limited commercial potential but high patient benefit, proposals should contain a deployment and sustainability plan including aspects related to regulations, certification and standardisation and patient access through healthcare providers.

Proposals should take into account sex, gender, age and other relevant socio-demographic variables to ensure the scientific robustness, clinical value and applicability of the targeted regenerative medicine innovation.

Applicants should provide details of their clinical studies 370 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2026-01-TOOL-06: Support to European Research Area (ERA) action on accelerating New Approach Methodologies (NAMs) to advance biomedical research and testing of medicinal products and medical devices

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 2.90 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.90 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, legal entities established in the United States of America may exceptionally participate as a beneficiary or affiliated entity, and are eligible to receive Union funding.

Coordinators of projects must be legal entities established in an EU Member State or Associated Country.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 371 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Member States and relevant stakeholders identify priority areas where New Approach Methodologies (NAMs) and infrastructures are most needed and expected to have the highest short- to medium-term impact.

2.Member States and other stakeholders jointly support the validation and qualification of a limited set of NAMs that are intended to be accepted and implemented in regulatory testing of medicinal products and medical devices.

3.Member States and other stakeholders develop common education and training programmes based on best practices identified in European and non-European countries to better inform researchers and regulators on NAMs and on the application of the 3Rs principles 372 .

4.Member States and other stakeholders implement a harmonised NAM openness and awareness programme that improves open access to NAMs protocols and results of animal experiments. It also provides guidance to harmonise the awareness of NAMs for ethical committee members, reviewers, and regulators, based on best practices in the participating Member States. The programme should propose concrete actions to increase the confidence of regulators in NAMs including a better understanding of the potential and limitations of NAMs.

Scope: This topic aims to coordinate and develop the new European Research Area (ERA) policy action to accelerate, through an aligned and coordinated approach across Member States and Associated Countries, the development, validation/qualification, acceptance, and uptake of NAMs in biomedical research and regulatory testing of medicinal products and medical devices as part of the ERA Policy Agenda 2025-2027 373 .

The ERA action should establish an EU-wide forum that brings together relevant ministries, regulatory agencies, research funding organisations, academia, industry (pharmaceutical and medical technology), Contract Research Organisations (CROs), small and medium-sized enterprises (SMEs) 374 , and startups to harmonise policies and strategies for NAMs development and implementation.

The selected proposal should be coordinated by any active participant to the ERA action to ensure consistency with ERA action policy objectives. It should contribute to the implementation of the following themes of the four thematic Working Groups (WGs) of the ERA action:

WG1: Development of NAMs and common European infrastructures. This WG identifies opportunities for the development and integration of NAMs and the establishment of supporting infrastructures. Its focus spans specific disease or biological areas and safety, quality, and efficacy assessment endpoints for medicinal products and medical devices. The WG provides insight and suggests priorities to governments and industry for the further coordinated efforts to leverage promising development of NAMs, taking into consideration the complementarity of scientific strengths, funding priorities and available expertise in the different Member States and regions.

WG2: Validation, acceptance, and uptake of NAMs. The WG defines optimal criteria for NAMs to facilitate their uptake in the contexts of basic and applied biomedical research, and their acceptance for the regulatory assessment and eventual approval of medicinal products and medical devices within defined contexts of use. It proposes priorities for the validation and qualification of NAMs. Member States and pharma/MedTech industry take the decision to jointly support the validation/qualification of certain NAMs that are sufficiently mature for acceptance and uptake in regulatory testing of medicinal products and medical devices.

WG3: Education and training. The WG maps existing education and training programmes on NAMs and the 3Rs principles and assesses their quality and outreach. The WG makes suggestions to Member States based on the best practices identified for the joint development of high-quality education and training modules on NAMs and the application of the 3Rs principles in close partnership with education directors at knowledge institutes.

WG4: Openness and awareness. The WG develops common policies to improve the openness and quality of research, including open access to available protocols on NAMs, and facilitating the publication of results from NAMs and animal experiments, even if these are negative or neutral (or historic, if feasible and appropriate), to avoid unnecessary duplication of animal testing or development of non-valid NAMs. It considers strategies for sharing best practices to make sure that different ethical committees, funding assessment committees, reviewers, and regulators have a similar level of awareness regarding the latest scientific advancements in available NAMs. It proposes actions to enhance the confidence of regulators in validated and qualified NAMs. The WG also identifies opportunities for raising awareness among civil society and patients regarding the biomedical research, drug discovery and development process.

The European Commission's Joint Research Centre (JRC) may contribute to the proposal selected for funding, particularly with activities on innovative in vitro biotechnologies.

HORIZON-HLTH-2026-01-TOOL-07: Establishing a European network of Centres of Excellence (CoEs) for Advanced Therapies Medicinal Products (ATMPs)

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.90 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.90 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, legal entities established in the United States of America may exceptionally participate as a beneficiary or affiliated entity, and are eligible to receive Union funding.

Coordinators of projects must be legal entities established in an EU Member State or Associated Country.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

Eligible proposals submitted under this topic and exceeding all the evaluation thresholds will be awarded a STEP Seal 375 .

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 376 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.In line with the objectives of the “Strategy for European Life Sciences” 377 , the EU successfully translates a strategic priority into an implementable action plan for building technological and innovation leadership on a global stage.

2.Europe, including regions, profits from an increased capacity, accessibility, coordination of its Advanced Therapies Medicinal Products (ATMP) infrastructures.

3.The European economy benefits from more ATMP innovations being developed and commercialised in the EU.

4.Patients across the EU gain faster access to innovative ATMPs thanks to increased and focused public Research and Development (R&D) investment, harmonised policies and strategies for ATMP development and uptake in healthcare systems.

Scope: ATMPs represent a frontier in medicine, offering groundbreaking treatments such as gene therapies, cell therapies, and tissue-engineered products that hold the promise of addressing complex and previously untreatable conditions. The European ATMP landscape is dynamic and promising, with 28 products having received marketing authorisation and many more in the pipeline 378 . The development of specialised infrastructures in Europe for these cutting-edge therapies is crucial for fostering innovation and ensuring fast and efficient delivery to patients in an equitable way. The report by Mario Draghi 379 on EU competitiveness, highlights that the EU’s share of the fast-growing global ATMP market is small, suggesting that to remain competitive, increased and focused public R&D investment is needed to complement ongoing efforts to streamline regulations and ensure faster pricing and reimbursement. The report recommends building on existing innovation hubs and expanding the capacity of the EU to conduct ATMPs R&D by the consolidation of EU public funds. By strengthening this budding innovation ecosystem, Europe can position itself as a leader in the ATMP sector, ultimately improving patient access to life-saving treatments and stimulating economic growth.

The EU has several scattered ATMP centres with divergent capacities and capabilities 380 , limiting its attractiveness for scaling up R&D in the field, calling for a coherent and coordinated approach. The aim of this topic is to establish a European network of Centres of Excellence (CoEs) for ATMPs, building on existing centres and coordinating their further development in synergy with national strategies. The creation of such a Network is key for strengthening the EU’s capacity to develop, scale up and deploy ATMPs across Europe, increasing Europe’s attractiveness for clinical research in the field and supporting the implementation of the “Strategy for European Life Sciences”. The CoEs should directly support the development and manufacturing capacity of ATMP-related biotechnologies, such as cell and gene therapy platforms, manufacturing infrastructure, and scale-up processes.

Each potential CoE should be an existing centre embedded within a vibrant biocluster (i.e. within proximity to pharmaceutical companies and research institutes) and should already benefit from critical infrastructure and services necessary to advance from lab to patient such as knowledge transfer support, state-of-the-art GMP 381 and clinical trials facilities. In addition, the centre should be performing the full spectrum of life sciences research, from discovery to clinical trials and should have demonstrated leadership in the field through a stand-alone research programme. Each CoE is expected to become world-class by further embedding itself in the full value chain and seeking additional political and financial support at regional, national and European level. The network should be limited to no more than 10 CoEs across the EU, with complementary expertise in the various ATMP technologies.

The proposed European network of CoEs for ATMPs should include multiple stakeholders beyond the research community and/or established academic centres, including Member State ministries, regional representatives, funders, regulators and healthcare payers, industry actors, patient organisations and policymakers. The European Commission's Joint Research Centre (JRC) may participate as a member of the consortium selected for funding, bringing its expertise in pre-normative research, standardisation, regulatory advice and access to its research infrastructure.

To align with STEP eligibility, activities supported under this topic should demonstrate how they contribute to either: i) bringing innovative, cutting-edge technologies with strong economic potential to the internal market, or ii) reducing or preventing the Union’s strategic dependencies in the field of advanced therapies.

Proposals should be of limited duration (2027-2030) and cover at a minimum the following activities:

1.Identify common needs and challenges related to ATMP R&D, as well as develop relevant policy recommendations related to clinical trials, manufacturing, logistics, regulatory (including harmonisation of market access authorisation and reimbursement procedures), public acceptance, policies for transnational care, and coordination with national/regional healthcare systems etc.

2.Develop a roadmap to ensure that Europe becomes the global leader for ATMP R&I by 2035, with clearly defined milestones, targets and Key Performance Indicators (KPIs). The roadmap should align with national R&D plans and include a long-term funding strategy. Appropriate measures should be considered to expand or widen the network during the roadmap’s implementation.

3.Create an advisory board with diverse stakeholders, as a forum to provide guidance and advice for ensuring maximum utility of the generated outputs.

4.Develop common education and training programmes for the next generation of scientists including outreach activities to better inform i) the public and patients on the benefits of ATMPs and ii) the stakeholders about access to the CoEs facilities and support.

Proposals should build on the experiences and outcomes of previous or ongoing actions such as RESTORE 382 , Join4ATMP 383 , PRECISEEU 384 and T2EVOLVE 385 , and liaise with the relevant partnerships such as the co-funded European Partnership on Rare Diseases 386 , the co-funded European Partnership for Personalised Medicine 387 and the Innovative Health Initiative Joint Undertaking (IHI-JU) 388 as appropriate.

HORIZON-HLTH-2027-02-TOOL-01-two-stage: Development of predictive biomarkers of disease progression and treatment response by using AI methodologies for chronic non-communicable diseases

Call: Cluster 1 - Health (Two stage - 2027)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 44.20 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

For the first stage, the thresholds for each criterion will be 4 (Excellence) and 4 (Impact). The overall threshold applying to the sum of the two individual scores will be set at a level that ensures the total requested budget of proposals admitted to stage 2 is as close as possible to four times the available budget, and not less than three and a half times the available budget.

For the second stage, the thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Clinical researchers and developers have access to novel predictive biomarkers to guide a more accurate assessment of disease progression and treatment response and tackle the unmet clinical needs of non-communicable chronic diseases.

2.Clinicians and healthcare professionals use clinically validated predictive biomarkers for implementing more effective clinical research and personalised medicine with better health outcomes in chronic non-communicable diseases.

3.Key stakeholders have access to trustworthy Artificial Intelligence (AI) tools to guide the development of multimodal predictive biomarkers of higher accuracy and clinical value when compared to the established practice.

4.The citizens benefit of better health outcomes thanks to improved clinical guidelines and the implementation of effective biomarker-guided clinical research and personalised healthcare.

Scope: Biomarkers 389 are invaluable tools for improving patient outcomes, guiding treatment decisions, accelerating personalised medicine, more effective clinical research and the development of better medicines.

However, despite the scientific discoveries of many clinically relevant biomarkers, estimated on the scale of tens of thousands, only a few biomarkers have been implemented in clinical practice. The traditional ‘one biomarker’ paradigm is insufficient for addressing the unmet clinical needs of chronic, progressive and multifactorial diseases, due to the complexity of the clinical phenotypes characterised by broad inter-and intra-patient heterogeneity. The established biomarkers have limitations in their use as prognostic and predictive indicators, for the assessment of the disease progression and the choices of the optimal therapeutic interventions tailored to the patients’ characteristics.

Therefore, the topic focuses on the clinical development of predictive biomarkers of disease progression and treatment response for chronic non-communicable diseases (excluding cancer) by using established AI methodologies able to combine data of clinically used and candidate biomarkers, with available data from relevant clinical studies, longitudinal and Real-World Data (RWD) 390 . This topic is expected to support collaborative projects paving the way for future innovations in personalised medicine and enabling more timely and effective therapeutic interventions.

The proposals should address all the following research and innovation activities:

1.Set-up a multidisciplinary collaboration to map and evaluate the available information and data on biomarkers currently used in the clinical setting, candidate biomarkers from past and ongoing clinical studies, which are scientifically proven as clinically relevant to the disease progression and treatment response for the chronic non-communicable diseases under study. This should include stratification by biological sex, and where feasible, integration of gender-related variables and sociodemographic determinants that may modulate disease trajectories or treatment efficacy.

2.Adapt and apply of established AI methods rather than developing novel ones from scratch, to deliver novel predictive biomarkers of disease progression and treatment response, by integrating data of currently used and candidate biomarkers, with suitable data from available longitudinal and other relevant clinical studies, including RWD, as necessary. To guarantee a solid and fast optimisation and training of the AI tools, the applicants should provide information in their proposal that the appropriate high-quality clinical data are readily available, and when necessary generate small-scale new data for the AI optimisation needs. The biomarkers under study should be multimodal, covering for instance molecular, cellular, physiological, imaging, behavioural and digital markers, and/or their combinations. The applicants should justify why the development of the biomarkers proposed is imperative to tackle the unmet clinical needs of the chronic non-communicable diseases under study.

3.Use AI and, where needed, other relevant data and knowledge integration methods, to describe the relationships among different biomarkers and support the robust prioritisation of predictive biomarkers tailored to the characteristics of the patients’ and their disease stage and treatment response. Proposals should have strong emphasis on the AI trustworthiness 391 and develop the adequate performance metrics to assess their accuracy, reliability, reproducibility, including the assessment of possible inherent bias. Use of AI and dataset should comply with existing privacy-preserving legislation. Moreover, proposals should consider the development of user-friendly and fit-for-purpose visualisation and decision-support tools to guide clinicians in evaluating the clinical plausibility of the biomarkers under study across diverse patient groups.

4.Establish a biomarker validation platform to assess the clinical utility of the predictive biomarkers identified. To this end, the applicants should implement clinical validation studies in independent disease cohorts, RWD and exploratory clinical studies, as appropriate, to demonstrate their clinical value as prognostic and predictive indicators for more effective clinical research and better patient health outcomes as compared to the established clinical practice of chronic non-communicable diseases. Prospective clinical studies are expected to be led by entities in the EU/EFTA and/or Associated Countries.

5.Develop a comprehensive exploitation plan for the valorisation of the research outputs and a regulatory strategy to support the alignment to the regulatory requirements for the qualification of the biomarkers and/or AI tools and engage with the regulators in a timely manner. The applicants should prioritise the exploitation of their research results in the EU. Participation of small and medium-sized enterprises (SMEs) 392 is encouraged with the aim to strengthen the scientific and technological basis of SMEs and valorise their health innovations.

Proposals should apply good practices for GDPR 393 compliant personal data protection.

Proposals are encouraged, where relevant, to exploit the available data services, expertise and digital tools offered by the relevant European research infrastructures 394 and/or data infrastructures 395  in the area of health funded under the Digital Europe Programme.

All proposals selected for funding under this topic will be strongly encouraged to participate in networking and joint activities (e.g. participation in joint workshops, development of best practices, or joint communication activities), which may also involve networking with projects funded under Horizon Europe, or other EU programmes (e.g. the Digital Europe Programme 396 ). The proposals should allocate a sufficient budget for networking and joint activities, without the prerequisite to detail such activities at the proposal stage.

Applicants should provide details of their clinical studies 397 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2027-03-TOOL-02: Advancing bio-printing of living cells for regenerative medicine

Call: Cluster 1 - Health (Single stage - 2027/2)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 7.00 and 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 39.30 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to most of the following expected outcomes:

1.Biomedical scientists from academia and industry will gain access to entire bio-printing units designed to regenerate human tissue.

2.Healthcare professionals acquire information on the safe and effective use of equipment enabling advanced therapies with bio-printed human tissue.

3.Healthcare providers dispose of tools enabling them to treat conditions of unmet medical need.

4.Individual patients will benefit from a personalised approach to their respective medical condition thanks to the bio-printed regenerative medicine solution.

Scope: Tissue-specific functional 3D bio-printing of living cells has made significant progress as a new approach for transplantation applications in regenerative medicine. There are currently several types of bio-printing technologies under development for the repair of different targeted tissues or organs. To fully unleash the potential of bio-printed cell constructs for regenerative medicine several bottlenecks still need to be overcome. Various studies in pre-clinical models have shown that bio-printed cell constructs or tissues hold great promise for regenerative medicine, by allowing autologous tissue grafts being printed thus avoiding adverse graft-host reactions. However, translation of such approaches into clinical settings (i.e. humans) and their application to internal organs still needs to be investigated and demonstrated. Dependant on the actual target site (i.e. the defect tissue or organ in the human body) different bio-printing approaches may be preferable. For printing complex tissues and especially entire organs an in-vitro approach followed by transplantation is the preferred way. “In-situ” bio-printing, sometimes also referred to as “in-vivo”, or as “intraoperative”, reflects a bioprinting process performed on a live subject in a surgical setting and has in certain instances (e.g. tissue repair) advantages over an in-vitro bio-printing technique followed by transplantation. In-situ bio-printing involves direct patterning of bio-inks onto a patient’s body at the target site, allowing for precise construction of a site-matching tissue-structure within the actual physiological location where regeneration or repair is needed. As such, in-situ bio-printing allows for high adaptability, reduced risk of contamination, improved cell viability, function and host integration. The high cell densities present in the human vital organs underscore the importance of bio-inks which contain less additional biomaterials as matrix. Hence the bio-printing of cell constructs that comprise native tissue-like cell densities may facilitate repair and/or regeneration of defective complex tissues or internal organs. For such approaches meticulous engineering of the bio-printing equipment is necessary, involving sophisticated micro-surgical instrumentation and medical imaging platforms. To achieve the desired function and to mimic the natural cues in native tissues for in-vitro printed bio-constructs, the use of additional stimuli is needed, whereas in-situ approaches normally rely on the body as natural bioreactor providing the necessary extracellular cues. Recently, combinations of in-situ bio-printing with real-time stimuli have been investigated, even for the repair of internal organs. However, there remain bottlenecks that need to be overcome, like the integration with existing imaging modalities and surgical procedures or the long-time stability and functionality of the created bio-constructs.

To address these challenges, researchers should work in multidisciplinary teams with engineers, biomedical scientists, cell biologists and medical doctors. Proposals should be based on the use of human cells and address all the following activities:

1.Develop or improve existing bioprinting equipment that comprises all steps of the bio-printing suite to print bio-constructs with high cell-density for improved vascularisation and faster repair of the defect in the body.

2.Scale-up the chosen bio-printing technology to a Good Manufacturing Practices (GMP) 398 conform/compliant manufacturing process.

3.Perform all necessary regulatory work enabling the conduct of clinical studies and assess the clinical value of the developed bio-printing technology in first in-human studies.

Priority should be given to bio-printing approaches that either target vital internal organs followed by surgical grafting or employ in-situ approaches depositing the cell-laden bioink directly from the printhead or endoscope on the defect target site in the body.

Regulatory knowledge of the field is desired and should be documented through contacts with relevant national or international European regulatory authorities. A good understanding of the different steps involved and the inherent risks in each of these steps will be a basis to identify appropriate safety and quality requirements. Requirements from the different established EU frameworks on Substances of Human Origin (SoHO), medical devices and pharmaceuticals including Advanced Therapy Medicinal Products (ATMPs) should be considered for manufacturing/preparation as well as for clinical outcome monitoring. A combination of requirements from different frameworks might be most appropriate to allow for responsible and fast uptake.

Proposals under this topic may address any therapeutic area, i.e. any disease, dysfunction or defect. Sex differences at the cellular level should be taken into consideration.

Preclinical stage and clinical development are eligible. The involvement of small and medium-sized enterprises (SMEs) 399 is encouraged.

The European Commission's Joint Research Centre (JRC) may contribute to the proposals selected for funding with work on strategic technologies for economic security and innovative industrial ecosystems, particularly activities on innovation in vitro biotechnologies.

Applicants should provide details of their clinical studies 400 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2027-03-TOOL-04: Virtual Human Twins (VHTs) for integrated clinical decision support in prevention and diagnosis

Call: Cluster 1 - Health (Single stage - 2027/2)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 10.00 and 12.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 39.30 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Healthcare professionals have access to multi-scale 401 , multi-organ models of individual patients that aim to improve prevention and diagnosis in high disease burden areas.

2.Health professionals benefit from enhanced knowledge of complex diseases and co-morbidities by recourse to multi-scale, multi-organ models.

3.Patients with diverse characteristics (e.g. of any sex, age group, racial or ethnic origin 402 ) benefit from improved, integrated and personalised prevention and diagnostics tools.

4.Health professionals and patients benefit from the use of “Virtual Human Twin” (VHT) models which enable integration of other preventive and diagnostic tools and modalities.

Scope: VHTs are digital representations and in-silico models of an individual’s health and disease state at different levels of anatomy. Multi-scale, multi-organ VHT solutions have a potential for tailored prevention and diagnosis, particularly in areas of high disease burden, and can significantly benefit citizens' health and the efficiency of EU health systems.

Proposals should take into account the work of projects funded under topic HORIZON-HLTH-2023-TOOL-05-03: “Integrated, multi-scale computational models of patient patho-physiology (‘virtual twins’) for personalised disease management”, which had a predominant focus on disease management, and focus on high-potential multi-disciplinary approaches at greater complexity (multiscale, multiorgan, longitudinal), strengthening their deployment in health and care, including the integration into care pathways and links with other decision support tools.

The proposals should address all the following activities:

1.Select clinical use cases to deliver multi-disciplinary, high impact solutions requiring multi-organ, multi-scale approaches to modelling complex pathophysiology over time, as a basis from where prevention and diagnosis of diseases with high morbidity and mortality could be enhanced. Proposals can put forward use cases in any areas of high disease burden; examples include co-morbidities, chronic cardiovascular conditions, infection and (auto)immunity, inflammation and cancer, diabetes and related conditions, rare diseases, degenerative diseases (including their interaction with mental health conditions), the exposome and its impact on human health and disease.

2.Building on current approaches, standards, data repositories (e.g. biobanks, environmental data, others) and modelling assets (e.g. those of the EDITH CSA 403 and the Platform for Advanced VHT Models 404 ), and new data if relevant, design, develop, extend and validate multi-organ, multi-scale, dynamic computational models that accurately simulate a person’s health and disease states, as necessary.

3.Evaluate, select, extend and validate diverse modelling methodologies, resulting in integrated, advanced, interoperable, patient-specific VHT models that can integrate diverse data sources and methodologies, addressing the chosen clinical use case requirements. Methodologies may include and are not limited to biophysics-based modelling, artificial intelligence (AI) that should be interpretable or allow explainability of outcomes, generative AI and in-silico modelling, agent-based and network physiology approaches. Evaluation, selection and extension of these should be documented during the design phase. Availability and integration of the multi-modal data should be documented, and the ethical and sex dimensions be investigated.

4.Demonstrate integration of these models with other advanced preventive and diagnostic modalities, tools and techniques enabling integration across pathways.

5.Generate evidence, including clinical validation, that the solutions deliver clinically meaningful decision support, addressing use case requirements. Document lessons-learned for broader application. Gather evidence via health economic and/or feasibility studies in real-world healthcare settings confirming cost-effectiveness vis-à-vis current practice (e.g. cost-effectiveness analysis). Produce an exploitation plan on regulatory compliance 405 and intellectual property.

Proposals should be multidisciplinary; solution design and development should be end-user-focused and draw on user and non-user input. Best practice in VHT software development including responsible AI development should be followed (e.g. risk assessment and management, requirements definition process).

Participation of small and medium-sized enterprises (SMEs) 406 is encouraged.

Proposals should contribute to the objectives of the European VHT Initiative 407 and to the Platform for Advanced VHT Models, with project assets made available on the Platform and interoperable with its technical specifications 408 ; relevant consortia members should join its User Community. Budget should be reserved for these activities. Projects are expected to collaborate with other EU-funded projects on VHTs 409 and align with relevant EU initiatives funded under Horizon Europe, the Digital Europe Programme 410 and the EU4Health Programme (2021-2027) 411 , e.g. European Cancer Imaging Initiative 412 , 1+Million Genomes Initiative 413 , Intensive Care Unit Data Space 414 , co-funded European Partnership for Personalised Medicine 415 , and projects on advancing AI in health where relevant.

This topic requires the effective contribution of social sciences and humanities (SSH) disciplines and the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

Applicants should provide details of their clinical studies 416 in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged.

HORIZON-HLTH-2027-03-TOOL-08: Towards Artificial General Intelligence (AGI) for healthcare

Call: Cluster 1 - Health (Single stage - 2027/2)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 2.90 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.90 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, or security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States and Associated Countries. Proposals including entities established in countries outside the scope specified in the topic will be ineligible.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 417

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 418 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Researchers and innovators benefit from an improved understanding of how to develop and use the next generation of frontier Artificial Intelligence (AI) models for healthcare, including how to leverage AI Factories and how to combine and expand the capabilities of existing foundation models towards inclusive and personalised medicine.

2.Researchers and innovators benefit from an improved understanding of how to leverage highly heterogeneous and multimodal health data spanning a range of anatomical scales (i.e. the micro to the macro level).

3.Multidisciplinary stakeholders have access to a collaboratively created roadmap for developing the next generation of frontier AI models for healthcare, towards Artificial General Intelligence (AGI) for healthcare.

Scope: The AI Continent Action Plan 419 identifies the health sector, encompassing life sciences, medical devices and healthcare delivery, as one of the key strategic sectors. The action will contribute to making European life sciences 420 and healthcare more impactful and productive by fostering the full integration of advanced AI in the health sector and biomedical research, along the objectives of the AI in Science strategy 421 and Apply AI strategy 422 .

Healthcare typically involves the combining of multimodal data, ranging from electronic health records through imaging and laboratory to molecular and omics data. This information combination is performed by specialists and is often challenging towards optimised patient care. In Europe, the growing amount of accessible multimodal health data, including via the forthcoming European Health Data Space (EHDS) 423 , combined with the increasing availability of high-performance computing facilities (e.g. AI Factories), presents a unique opportunity to develop the next generation of frontier AI models for healthcare. This action anticipates and operationalises the use of such federated infrastructures for research and innovation. Moreover, regulations such as the EHDS regulation and AI Act 424 steer the direction into building an ecosystem fostering ethical and safe innovation on AI in healthcare.

AI models are becoming increasingly complex and able to tackle increasingly challenging tasks. The next generation of frontier AI models are expected to make strides towards AGI, a type of AI capable of tackling highly complex and diverse tasks with proficiency comparable to that of humans. This topic will lay the foundation for the development of the next generation of frontier AI models, paving the way for new, advanced AI-powered solutions to increase efficiency and efficacy in the health sector towards improved patient outcomes. It will leverage results, methodologies, data etc. of other relevant EU-funded projects.

Proposals should include all the following coordination and support activities, ensuring multidisciplinary approaches and a broad representation of stakeholders in the consortium (e.g. healthcare professionals, patients, biomedical scientists, AI developers, data engineers, ethics experts):

1.Community building: build a large-scale and diverse pan-European community of stakeholders with the multidisciplinary expertise united as required to develop the next generation of frontier AI models for healthcare, towards AGI for healthcare, with a view to leveraging as a community the potential of AI Factories. Where relevant, this should build on and strengthen existing EU-funded communities and networks, and could pave the way for a formalised long-term collaboration under one of the available EU instruments.

2.Roadmap creation: review previous research to identify the most promising AI models and model development approaches. In addition, risk assess and review evidence on safety and efficacy of existing AI models with reference to the AI Act, related regulatory provisions (including any jurisprudence) and ethical and security considerations, so that frontier AI model development can proceed on a well-informed basis. Finally, create a roadmap for developing the next generation of frontier AI models.

3.Dataset identification, curation, expansion and use: i) identification: identify the most suitable existing datasets for the development of frontier AI models for healthcare, ii) curation: identify how to validate the datasets, ensure dataset interoperability, and convert datasets into formats suitable for frontier AI model development, iii) expansion: identify additional datasets and/or annotations required for frontier AI model development, especially to ensure that datasets are representative and iv) use: identify methods and required infrastructure to allow privacy-preserving use and further expansion of the datasets in alignment with and through the EHDS.

4.Frontier AI model preparatory activities: mapping approaches for training and evaluating frontier AI models (e.g. approaches to combine foundation models for life sciences and healthcare delivery in order to develop more advanced and multidisciplinary models towards personalised medicine). The approaches should cover all trustworthy AI aspects 425 .

This action should take into account the results of other relevant projects on AI in health, in particular in the two GenAI4EU topics HORIZON-HLTH-2025-01-CARE-01: “End user-driven application of Generative Artificial Intelligence models in healthcare (GenAI4EU)” and HORIZON-HLTH-2025-01-TOOL-03: “Leveraging multimodal data to advance Generative Artificial Intelligence applicability in biomedical research (GenAI4EU)”, and leverage the AI Factories and specialised health data infrastructures funded under the Digital Europe Programme 426 , biobanks, relevant ERICs 427 , as well as the data resources accessible through the EHDS infrastructure starting in 2029, funded under EU4Health Programme (2021-2027) 428 .

Destination - Maintaining an innovative, sustainable, and competitive EU health industry

Topics under this destination are directed towards the Key Strategic Orientation 3 “A more resilient, competitive, inclusive, and democratic Europe” of Horizon Europe’s strategic plan 2025-2027 429 . In addition, Key Strategic Orientation 2 “The Digital Transition” and Key Strategic Orientation 1 “The Green Transition” are supported.

Research and Innovation supported under this destination should contribute to the following expected impact, set out in the strategic plan impact summary for the Health Cluster: “the EU health industry is innovative, sustainable, and globally competitive thanks to improved uptake of breakthrough technologies and innovations (including social innovations) that make the EU with its Member States and Associated Countries more resilient and less reliant on imports of critical health technologies”.

The health industry is a key driver for growth and has the capacity to provide health technologies to the benefit of patients and providers of healthcare services. The relevant value chains involve a broad variety of key players from supply, demand and regulatory sides. In addition, the path of innovation in health is long and complex. The development of novel health technologies is generally associated with uncertainties and market barriers due to expensive and risky development (e.g. high attrition rate in pharmaceutical development), high quality and security requirements (e.g. clinical performance, safety, data privacy and cybersecurity) and market specificities (e.g. strong regulation, pricing and reimbursement issues). In addition, the growing concern about environmental issues is putting more pressure on this industry. Therefore, there is a need for Research and Innovation integrating various stakeholders to facilitate market access of innovative health technologies (medical technologies, pharmaceuticals, biotechnologies, digital health technologies).

In line with the Commission's Political Guidelines for 2024-2029 430 , and building on the recommendations of the reports by Mario Draghi 431 and Enrico Letta 432 , as well as the “Strategy for European Life Sciences” 433 , this destination will support research and innovation to enhance the competitiveness of the European health industry, thereby reinforcing EU autonomy, consolidating its Single Market, and empowering Europe to effectively address the burden of both communicable and non-communicable diseases. In this Work Programme part, Destination “Maintaining an innovative, sustainable, and competitive EU health industry” focuses on collaborative efforts to advance cell-free protein synthesis platforms, ready-to-use point-of-care diagnostics, and regulatory science to support translational development of patient-centred health technologies. The results will support the EU Industrial Policy, with a focus on strengthening the resilience of the single market, addressing the EU’s strategic dependencies, gaining technological sovereignty and accelerating the green and digital transitions. The results will further strengthen the single market, by providing evidence and guidelines for stakeholders and regulators to ensure adoption of innovations, supporting environmental, fiscal and socio-economic sustainability and at the same time fostering healthcare access and reducing health inequities. The results will also support the implementation of the relevant Regulations like those on Medical Devices (MDR) and In-Vitro Medical Devices (IVDR) as well as the general uptake of innovative health technologies by health systems, with a special view to aspects related to ensuring industry competitiveness, fostering innovation and sustainability, while maintaining the high level of quality, safety and efficacy of these health technologies.

In view of increasing the impact of EU investments under Horizon Europe, the Commission welcomes and supports cooperation between EU-funded projects to enable cross-fertilisation and other synergies. This could range from networking to joint activities such as the participation in joint workshops, the exchange of knowledge, development and adoption of best practices, or joint communication activities. All topics are open to international collaboration to address global environment and health challenges.

Expected impacts:

Proposals for topics under this destination should set out a credible pathway to contributing to maintaining an innovative, sustainable and competitive EU health industry, and more specifically to one or several of the following expected impacts:

1.Health industry in Europe and Associated Countries is more competitive and sustainable, assuring European leadership in breakthrough health technologies and open strategic autonomy in essential medical supplies and (digital) technologies, contributing to job creation and economic growth, in particular with small and medium-sized enterprises (SMEs) 434 .

2.Health industry is supported by cross-sectoral Research and Innovation in the context of convergence of health technologies (integrating medical technologies, pharmaceuticals, biotechnologies, digital health, and e-health technologies) while strengthening key market positions.

3.Health industry is working more efficiently along the value chain from the identification of needs to the scale-up and take-up of solutions at national, regional or local level, including through early engagement with patients, healthcare providers, health authorities and regulators ensuring suitability and acceptance of solutions.

4.Citizens, healthcare providers and health systems benefit from a swift uptake of innovative health technologies and services through the provision of evidence and guidelines for stakeholders, policymakers and regulators. These efforts offer significant improvements in health outcomes, also potentially strengthening access to healthcare for all and reducing health inequities while health industry benefits from decreased time-to-market.

5.Citizens, healthcare providers and health systems benefit from increased health security in Europe and Associated Countries due to reliable access to key manufacturing capacity, including timely provision of essential medical supplies and technologies of particularly complex or critical supply and distribution chains.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in the Annex B of the General Annexes of this Work Programme.

The protection of European communication networks has been identified as an important security interest of the Union and its Member States. Entities that are assessed as high-risk suppliers 435 of mobile network communication equipment (and any entities they own or control) are not eligible to participate as beneficiaries, affiliated entities and associated partners to topics identified as “subject to restrictions for the protection of European communication networks”. Please refer to the Annex B of the General Annexes of this Work Programme for further details.

Proposals are invited against the following topic(s):

HORIZON-HLTH-2026-01-IND-03: Regulatory science to support translational development of patient-centred health technologies

Call: Cluster 1 - Health (Single stage - 2026)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.00 and 6.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 19.60 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 436 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Maintaining an innovative, sustainable, and competitive EU health industry”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to several of the following expected outcomes:

1.Policymakers and regulators will get accelerated access to improved evidence driven methodologies to evaluate the impact and efficiency of novel health technologies, facilitating decision-making for their use in humans and uptake in clinical practice.

2.Patients and the health systems will benefit from the more targeted and efficient uptake of safe and effective health innovations in clinical practice, supporting more personalised approaches and improved care and public health.

Scope: The development, uptake and impact of health technologies typically results from a long product development process that is based on a 'life cycle approach' which typically involves several iterations of defined stages, i.e. from development, assessment to post-market surveillance and post-market clinical follow-up.

While health technologies are governed by comprehensive legal frameworks aiming to ensure that health technologies are safe and effective, the regulatory science underlying these legal frameworks needs to be updated. This concerns inter alia i) more precise delineation of specific requirements (e.g. closing existing gaps concerning sufficiency of clinical evidence) and ii) the consideration of novel biomedical approaches, data and digital solutions (e.g. artificial intelligence - AI, virtual human twin, new approach methodologies as well as methods that cut through these domains) which model and predict relevant biological parameters and exploit relevant end-points and novel (bio)markers for clinical diagnostic and prognostic predictions. Such update of the regulatory science of health technologies should aim at supporting an effective adoption and uptake into routine use by health systems and end-users (healthcare providers, citizens), while maintaining guardrails to ensure that innovative health technologies are backed up by evidence of sufficient quality and relevance to the human situation.

Proposals can cover all types of health technologies, aiming to define improved and novel sources of evidence with proven relevance for regulatory decision-making with a focus on safety and performance throughout their lifecycle, i.e. throughout the continuous process of clinical evaluation. To this end, proposals should address either, or a combination of the following: i) the improvement of existing methodologies and their fitness to specific types or classes of health technologies, including methodology for regulatory assessment and ii) explore and examine to which extent novel information sources as indicated above can be considered as evidence that is satisfactory in view of regulatory needs concerning safety and performance.

Proposals should support the update and refinement of regulatory science on health technologies and contribute actionable information that can be used for improved or novel regulatory policies, rules, guidance documents and other tools with a view to ensuring that European patients and healthcare professionals have access to safe and effective innovative health technologies. Proposals should ultimately contribute to a regulatory environment that makes use of the full spectrum of novel biomedical and bio-digital approaches for clinical investigation and evaluation, while promoting a patient-centred approach to health technology innovation, facilitating the timely entry to market of performant and effective innovations and support their uptake in the health systems and clinical workflows without compromising patient safety.

Applicant consortia should reflect a broad representation of stakeholders, notably clinical societies, academia, notified bodies, industry, patients and regulators and the proposed work should address one or more of the following elements:

1.Data and analyses on how existing approaches in regulatory science can be refined and improved in view of closing existing gaps of clarity, sufficiency of clinical evidence, generated on the basis of clinical studies and clinical investigations.

2.Data and analyses on whether and to which extent novel information sources from biomedicine including new approach methods and digital and AI-enabled models and approaches can contribute to the clinical evaluation of innovative health technologies, e.g.:

1.By providing information on relevant biophysical, anatomical, physiological and other disease-relevant aspects.

2.By supporting information integration through the use and aggregation of already existing data, including clinical ones, from similar types or groups of technologies (e.g. retrospective information in registries, data collections, including Real-World Data (RWD) 437 from using technologies that have characteristics that are relevant for innovative technologies).

3.By supporting improved planning and design of first-in-man clinical studies, with a view of enhancing the effectiveness and the safety of such studies and rationalising the use of resources of all involved actors by focusing the generation and assessment of clinical data on health technologies for which those data are indispensable.

3.Data and analyses that examine to which extent the above-mentioned points can support the development and uptake of innovative technologies for unmet medical needs and for special patient populations (e.g. paediatric and rare conditions) via dedicated regulatory pathways and/or within a structured framework enabling their development and testing in a real-world environment under regulatory supervision (“regulatory sandbox”).

The actual conduct of clinical studies 438 is not in scope of this topic.

The activities should cover and draw on all the relevant healthcare innovation related frameworks other than pharmaceutical products, i.e. medical devices, in-vitro diagnostics, AI, and Substances of Human Origin (SoHO).

The starting point is a good understanding of the innovative technology and of its inherent risks, so that appropriate safety and quality requirements can be applied for monitoring the outcome in the relevant healthcare setting. As the number of hybrid or combinations of health technologies increases and technology integration becomes rather the norm than an exception in health innovation, the current segregated, technology-specific, frameworks may not provide a clear path forward for the health technology that is targeted. To that end, when considering an innovation, it is important to consider all relevant legislative frameworks including MDR 439 and IVDR 440 , the proposed SoHO-Regulation 441 , and AI Act 442 among others.

Proposals are encouraged to consider, where relevant, the data, expertise and services offered by European research infrastructures especially those active in the health domain, such as EATRIS ERIC 443 , and also the findings of previous EU-projects (e.g.: CORE-MD 444 ).

HORIZON-HLTH-2027-01-IND-01: Development of cell-free protein synthesis platforms for discovery and/or production of biologicals

Call: Cluster 1 - Health (Single stage - 2027/1)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 24.50 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Maintaining an innovative, sustainable, and competitive EU health industry”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Biopharmaceutical industries get access to streamlined development and production processes for peptide- or protein-based biologicals.

2.Health systems benefit from the availability of enhanced or decentralised production systems for innovative health technologies that involve peptides or proteins, and which improve health and care.

3.Citizens and patients will benefit from better access, availability and affordability of pharmaceuticals based on biologicals.

Scope: Cell-Free Protein Synthesis (CFPS) has been employed in fundamental biological research for decades, however, interest for the approach as a viable means for drug development and production has only emerged in recent years. The advantages that CFPS provides in terms of efficiency, simplicity, flexibility, cost- and time savings outweigh the hurdles that are still to be overcome for CFPS to become a routine manufacturing system for peptide- or protein-based biologicals.

Currently, there are several CFPS systems used that are either based on prokaryotic or eukaryotic cell lysates (including mammalian) or fully synthetic systems consisting of all the molecular machinery necessary to create functional proteins. The choice of a specific lysate is dictated by the target protein and the end-use application. Proteins that require post-translational modification are generally produced using lysates of mammalian cells. Hence systems based on mammalian cells are of particular interest as they combine properties inherent to eukaryotic cells and their ability to produce human-like glycosylated proteins with the advantages of cell-free synthesis. These proteins include antibody fragments, antigens, virus-like particles, cytokines, enzymes, antimicrobial peptides and proteins containing non-natural amino acids. The benefits of CFPS are manifold, from ease of handling and scalability, on-demand launch of production, ability to rapidly switch products, simplified purification to facilitated standardisation and quality control. CFPS needs less energy resources, the manufacturing footprint is less complex and smaller than in cell cultivation and it enables production of proteins that have toxic effects on cells. In addition, CFPS has the potential as an enabling technology for personalised medicines and is amenable to decentralised manufacturing. CFPS has gained even more interest in the recent past owing to advances in synthetic biology and thanks to the rise of Machine-Learning/Artificial Intelligence (ML/AI). The use of generative deep learning and artificial intelligence has high potential in the de-novo design of biomolecules with specific properties of therapeutic and/or preventive nature. CFPS offers here great opportunities to increase the throughput in screening of the de-novo created biomolecules.

The application of synthetic biology, potentially also combined with generative AI, and cell-free biosynthesis open up new avenues for the design, discovery and manufacture of therapeutics not only against infectious diseases, but also non-communicable diseases and equally for vaccines.

Proposals should address at least two of the following elements:

1.Address the bottlenecks that currently hamper the large-scale deployment of CFPS, i.e. the lack of a quality-by-design approach, the need to fully characterise the underlying cell lysates and their critical quality attributes and the need for better understanding of the correlations between specific cell lysate properties and CFPS process parameters, specific product quality attributes (such as protein folding), and CFPS platform performance.

2.Use synthetic biology techniques for the design of de-novo biomolecules with specific desired properties (antimicrobial, immunogenic, angiogenic, etc.) and develop suitable cell-free systems for the high-throughput screening of the designed biomolecules.

3.Develop novel or optimise existing CFPS platforms for the production of the targeted biomolecule to a Good Manufacturing Practices (GMP) 445 conform process, producing clinical-grade material that can be tested in clinical trials.

The demonstration of the superiority of the developed CFPS platform as compared to the current state-of-the art production system for a specific therapeutic peptide or protein would be an asset and participation of start-ups, micro, small and medium-sized enterprises (SMEs) 446 is encouraged.

Applicants envisaging to include clinical studies 447 should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

HORIZON-HLTH-2027-02-IND-02-two-stage: Portable and versatile Point-of-care diagnostics

Call: Cluster 1 - Health (Two stage - 2027)

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 7.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 39.30 million.

Type of Action

Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

For the first stage, the thresholds for each criterion will be 4 (Excellence) and 4 (Impact). The overall threshold applying to the sum of the two individual scores will be set at a level that ensures the total requested budget of proposals admitted to stage 2 is as close as possible to four times the available budget, and not less than three and a half times the available budget.

For the second stage, the thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 448 .

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Maintaining an innovative, sustainable, and competitive EU health industry”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

1.Healthcare professionals dispose of diagnostic tools at the point of care that accelerate therapeutic decision making.

2.Patients benefit from fast and accurate diagnosis leading to improved health outcomes.

3.Thanks to more efficient diagnosis, health systems will get better evidence for disease control and prevention strategies.

Scope: Point-of-Care (PoC) medical testing has made great technical progress (e.g. improved extraction, microfluidics, miniaturisation, and data processing techniques) with PoC test accuracies nearly matching those of lab-based tests. PoC tests may thus be an alternative to laboratory testing methods, enabling faster diagnostic results and therapeutic decision making. However, PoC testing is not always achieving a completely accurate diagnosis and one of the major issues with PoC diagnostics is the occurrence of false results during testing, another one is the often-cumbersome sample preparation. Hence there is a need for PoC diagnostics that are more sensitive, selective and easy-to-use allowing for improved clinical practice.

The World Health Organization (WHO) has defined a set of criteria for PoC diagnostics in primary care which, in the advent of digital technologies, has been completed with two additional features and is represented by the acronym REASSURED: Real-time connectivity, Ease of specimen collection and environmental friendliness, Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment-free (or equipment-modest) and Deliverable to end users. To these criteria adds the feature of “sample-to-answer” (sometimes also called “sample-to-result”) and more challenges like: Miniaturisation, power supply, versatility (nature and origin of the human sample), biocompatibility of the used materials and their suitability for mass production, readiness for high-throughput testing, quality control, regulatory compliance, environmental footprint and, last but not least, cost, which is of particular concern in resource-limited settings. All these challenges are not only valid for PoC diagnostics developed for infectious diseases, they equally apply to those that are designed to detect non-communicable diseases as well as their continuous monitoring on patients. Mobile technologies are playing an important role, especially since around 70% of the globally 7.4 billion cell phone users live in developing countries, which are the areas in direct need of advanced and more accessible PoC diagnostics (lower density of relevant health infrastructure, e.g. hospitals and laboratory medicine testing facilities). Mobile phones have not only been proposed and tested for data acquisition and readout of assays, images and other results but also for sample processing (e.g. for heating step), as have been Machine-Learning/Artificial Intelligence (ML/AI) powered algorithms that are integrated in the diagnostic devices to analyse complex biological data and detect patterns that might be missed by human analysis.

The selection of the PoC device to be developed or optimised should be based on an objectively conducted clinical needs assessment, which includes -next to clinicians’ perspectives- the complete care pathway and system-level needs. Moreover, a value-based concept should be applied in the choice and development of the PoC device, taking into account its Health Technology Assessment (HTA) by the relevant HTA bodies, in order to facilitate their decisions for adoption.

Proposals should be driven by a clear clinical need, integrate a value-based concept and include all the following activities:

1.The optimisation of (the) targeted PoC diagnostic device(s) that take(s) the above-mentioned criteria, challenges and aspects into consideration.

2.The elaboration of a comparative study clearly demonstrating the added value and improved performance of the optimised PoC diagnostic device(s) as compared to the current state of the art for the targeted diagnostic application.

3.The conduct of clinical studies of (the) optimised PoC diagnostic medical device(s) as a preferred information source for their clinical validation; subsequent conformity assessment in agreement with requisite EU’s In-Vitro Medical Device (IVDR) or Medical Device (MDR) regulatory requirements.

In general, priority should be given to approaches that are suitable for resource-limited settings. In case of targeting infectious diseases, priority should be given to approaches enabling the distinction between viral, bacterial or fungal infections. In case of targeting non-communicable diseases, priority should be given to approaches that are used in emergency cases where decisions can have life-saving character.

Applicants invited to the second stage and envisaging to include clinical studies 449 should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

Other Actions not subject to calls for proposals

Grants to identified beneficiaries

1. Contribution to the activities of the Coalition for Epidemics Preparedness Initiative (CEPI) in 2026

The Coalition for Epidemic Preparedness Innovations (CEPI) is a global initiative focused on vaccine development for pathogens causing epidemic threats. It has played a crucial role in the Union's response to COVID-19. This funding will enable CEPI to issue competitive calls to develop medical countermeasures for diseases with epidemic potential. The grants will support research on new vaccines to prevent future epidemics.

Expected Outcome: Proposals should set out a credible pathway to contributing to one or several expected impacts of destination: “Tackling diseases and reducing disease burden”. Project results under this action are expected to contribute to all the following expected outcomes:

1.Healthcare providers have access to newly developed medical countermeasures against prioritised pathogens with epidemic potential.

2.Citizens benefit from improvements in prevention and containment of epidemics.

3.Research funders, policymakers and the research community will have better tools for achieving Sustainable Development Goal (SDG) 3.3 450 “to combat communicable diseases” and to implement SDG Target 3.b 451 “to support the research and development of vaccines and medicines for the communicable and non-communicable diseases”.

Scope: CEPI is an international non-profit association established under Norwegian Law. Its objective is to finance and coordinate the development of new vaccines to prevent and contain infectious diseases that have epidemic potential. The Horizon Europe funding will be used to enhance and expand CEPI’s activities. This action will also contribute to the implementation of the Union’s strategy for international cooperation in research and innovation and the EU’s development policy.

Accordingly, the proposals should cover all the following activities:

1.Vaccine research and development for emerging pathogens.

2.Development of adaptable vaccine technologies.

3.Collaboration with stakeholders in epidemic preparedness.

This action is expected to engage with other relevant initiatives, such as the co-funded European Partnership for Pandemic Preparedness 452 and the European Vaccine Hub 453 .

With the grant from the European Union, CEPI will be able to award one or several grants to third parties through competitive calls for proposals. The call(s) will be issued to fund advanced pre-clinical as well as clinical research on new vaccines for the prevention of emerging and re-emerging infectious diseases. For this purpose this action is also expected to engage with HERA, and support the EU policy goals of scientific leadership in pharmaceutical research and development and strategic autonomy. Therefore, in its financing of third parties, this action should favour activities conducted in Member States or Associated Countries. Such activities may include early-phase clinical trials, and/or enabling activities, for instance the manufacturing of GMP-grade 454 batches of investigational products. The action is expected to incentivise the development of local expertise and strengthen regional scientific capacities in Member States and Associated Countries, in balance with the overarching need to prioritise scientific excellence as well as logistical and strategic considerations.

The expected recipients of the grant(s) issued by CEPI include research institutes, universities, small and medium-sized enterprises (SMEs) 455 as well as large companies, all active in research and innovation on new and improved vaccines.

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation to CEPI, as CEPI has been a key partner for implementing the common Union response to the COVID-19 epidemic.

Award criteria:

The criteria are described in General Annex D. The following exceptions apply: The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements:

The funding rate will be 70%.

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Financial support provided by CEPI to third parties is one of the primary activities of this action in order to be able to achieve its objectives as CEPI does not have the capacity to develop new medical countermeasures itself. The maximum amount to be granted to a third party is EUR 15 million. This is justified by the high cost of development for new vaccines, that reaches tens of millions of Euros 456 . However, if the objectives of the action would otherwise be impossible or overly difficult (and duly justified in the proposal) the maximum amount may be higher.

Legal entities:

Coalition for Epidemic Preparedness Innovations, Marcus Thranes gate 2, 0473 Oslo, Norway

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Programme co-fund action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Fourth Quarter of 2026

Indicative budget: EUR 39.30 million from the 2026 budget

2. Presidency event - Ireland. Bridging Worlds - Climate Change and Health through the lens of the One Health Agenda - Research, Innovation and Problem Solving

This action will cover the organisation of a conference by the Irish Presidency, focusing on the impacts of climate change on Health and the research needs within the wider context of the One Health agenda.

The impacts of climate change present significant threats to public health, including extreme heat, exacerbated health effects of pollution, antimicrobial resistance, zoonotic transfer of pathogens, shifting diseases vectors, and food and water availability and quality.

In recent years, the importance of adopting a One Health approach has become increasingly evident, particularly in Research and Innovation. These efforts are vital to safeguard human, animal, and plant health, alongside their shared environments and economic competitiveness.

The conference should be informed by key EU initiatives such as:

1.The Commission’s Scientific Advice Mechanism (SAM) opinion on One Health 457 supporting an integrated approach and emphasising the importance of interdisciplinary and cross-sectoral collaboration, including in research and innovation.

2.Actions and initiatives focusing on optimising the health of people, animals, and ecosystems, such as the co-funded European Partnerships on One Health Anti-Microbial Resistance 458 and on Animal Health and Welfare 459 and the co-funded European Partnership for Pandemic Preparedness 460 , and including the European Climate and Health Observatory 461 and the EU Global Health Strategy 462 .

3.The Strategic Research and Innovation Agenda (SRIA) on Health and Climate change, reflecting key concepts in One Health such as inter- and transdisciplinary research, or the role of vectors in the climate related spread of infectious diseases.

This conference will champion the One Health agenda as the foundational framework for building climate-resilient health systems across Europe. By fostering cross-disciplinary collaboration the complex health threats posed by climate change can effectively be addressed and mitigated, moving from reactive responses to proactive prevention and sustainable adaptation.

The conference will create an opportunity for policymakers, national health ministries, research institutions, experts, academics public health agencies, environmental organisations, agricultural sector representative and civil society to share innovative research and solutions to solve climate change-related health risks.

The conference should aim to address the following goals:

1.Highlighting and promoting innovative research and evidence-based solutions from across EU Member States being developed under One Health agenda, focusing on:

1.Climate Change Impacts on Health and Ecosystems: i) emerging and re-emerging zoonotic diseases, antimicrobial resistance and climate change, ii) food and water security challenges in a changing climate and their health implications, iii) supporting healthcare provision during the green transition.

2.Advancing Research and Innovation for Climate-Resilient One Health Systems: i) cutting-edge data surveillance and early warning systems for climate-sensitive health threats, ii) sustainable agriculture and food systems for health and climate mitigation.

3.Policy, Governance, and Implementation: i) integration of One Health polices and datasets into national and European climate adaptation strategies and health policies, ii) guidance that has been developed -or is under development- to strengthen interdisciplinarity in research and innovation, along with mechanisms to assess the effectiveness of One Health implementation, iii) public engagement, communication, and education for One Health and climate action.

2.Facilitating knowledge sharing and networking across a wide range of disciplines together to and spark inspiration on climate and health challenges.

3.Building on the “Strategy for European Life Sciences” 463 aiming to strengthen life sciences research and innovation in Europe, supporting wide ranging green transitions.

4.Building on the Strategic Research Agenda on health and climate change, identifying research gaps and data infrastructure requirements relevant to progressing climate and health under a One Health agenda.

This event would result in a proceedings paper to underpin a call for action to foster inter- and transdisciplinary collaboration in research and innovation at the intersection between climate and health and the One Health Agenda so as to help inform relevant policies being developed at both EU and Member State level.

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation to the legal entity identified below.

Award criteria:

The criteria are described in General Annex D. The following exceptions apply: The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure:

The evaluation committee will be composed fully by representatives of EU institutions.

Legal and financial set-up of the Grant Agreements:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 464 .

The funding rate will be 100%.

Subcontracting is not restricted to a limited part of the action.

Legal entities:

Department of Health, Government of Ireland, 50 - 58, Block 1, Miesian Plaza, Baggot Street Lower, Dublin 2, D02 XW14

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: First Quarter of 2026

Indicative budget: EUR 0.30 million from the 2026 budget

3. Presidency event - Lithuania. Strengthening the European clinical research ecosystem for advanced therapy medicinal products and substances of human origin

This action will cover the organisation of a high-level conference by the Lithuanian presidency, focusing on strengthening the European clinical trials ecosystem with a particular emphasis on Advanced Therapy Medicinal Products (ATMPs) and Substances of Human Origin (SoHO). These innovative therapies which offer the potential for regeneration or repair, involve complex trials but are central to Europe’s ambition to become a global leader in cutting-edge medical research and patient-centred care. The decline of clinical research activity in Europe not only impacts economic competitiveness but also limits patient access to transformative therapies, especially in areas such as rare diseases, oncology, and regenerative medicine.

ATMPs and SoHO-based interventions -including cell and gene therapies, tissue-engineered products, and treatments derived from blood, plasma, or other human sources- face unique scientific, regulatory and operational challenges. These include heightened ethical considerations, complex trial logistics, and fragmented regulatory interpretations. As the EU continues to lag significantly in ATMP clinical trial activity, this event aims to build momentum for targeted action, drawing on recent EU initiatives such as the “Biotechnology and Biomanufacturing Communication” 465 , the “Strategy for European Life Sciences” 466 and the upcoming Biotech Act 467 .

This conference will bring together policymakers, regulators, academic and clinical researchers, patient representatives, and industry experts in the field of regenerative medicine to align efforts on advancing innovation, ensuring robust regulation, accelerating patient access, and fostering collaboration across the European health ecosystem.

The conference should aim to address the following goals:

1.Identify key obstacles to effective implementation of ATMP and SoHO clinical research in the EU and Associated Countries, including regulatory fragmentation, variability in ethics review, manufacturing, site activation delays, funding and lack of trial-readiness.

2.Highlight best practices from countries supporting innovation-friendly environments, including national strategies and reimbursement policies.

3.Explore enabling infrastructures for ATMP and SoHO product development, such as academic clinical trial networks and decentralised, hospital-based manufacturing of ATMPs.

4.Advance policy recommendations aimed at supporting pan-European ATMP/SoHO networks, fast-track regulatory pathways, and strategic investment in trial and manufacturing capacity and capabilities.

The outcomes of the conference will directly inform EU-level policy discussions on the future of ATMP and SoHO clinical research ecosystems, the next Research and Innovation (R&I) framework programme, the European Health Union 468 , and the European Medicines Regulatory Network 469 , contributing to a resilient and innovation-driven health system across the EU.

By focusing on ATMPs and SoHO-based interventions, this initiative underscores the EU’s commitment to the EU’s competitiveness as well as scientific excellence, health sovereignty, and equitable patient access to frontier therapies.

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation to the legal entity identified below.

Award criteria:

The criteria are described in General Annex D. The following exceptions apply: The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure:

The evaluation committee will be composed fully by representatives of EU institutions.

Legal and financial set-up of the Grant Agreements:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 470 .

The funding rate will be 100%.

Subcontracting is not restricted to a limited part of the action.

Legal entities:

Ministry of Health of the Republic of Lithuania, Vilniaus g. 33, Vilnius, 01506 Vilniaus m. sav., Lithuania

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Third Quarter of 2026

Indicative budget: EUR 0.30 million from the 2026 budget

4. Contribution to the activities of the Coalition for Epidemics Preparedness Initiative (CEPI) in 2027

The Coalition for Epidemic Preparedness Innovations (CEPI) is a global initiative focused on vaccine development for pathogens causing epidemic threats. It has played a crucial role in the Union's response to COVID-19. This funding will enable CEPI to issue competitive calls to develop medical countermeasures for diseases with epidemic potential. The grants will support research on new vaccines to prevent future epidemics.

Expected Outcome: Proposals should set out a credible pathway to contributing to one or several expected impacts of destination: “Tackling diseases and reducing disease burden”. Project results under this action are expected to contribute to all the following expected outcomes:

1.Healthcare providers have access to newly developed medical countermeasures against prioritised pathogens with epidemic potential.

2.Citizens benefit from improvements in prevention and containment of epidemics.

3.Research funders, policymakers and the research community will have better tools for achieving Sustainable Development Goal (SDG) 3.3 471 “to combat communicable diseases” and to implement SDG Target 3.b 472 “to support the research and development of vaccines and medicines for the communicable and non-communicable diseases”.

Scope: CEPI is an international non-profit association established under Norwegian Law. Its objective is to finance and coordinate the development of new vaccines to prevent and contain infectious diseases that have epidemic potential. The Horizon Europe funding will be used to enhance and expand CEPI’s activities. This action will also contribute to the implementation of the Union’s strategy for international cooperation in research and innovation and the EU’s development policy.

Accordingly, the proposals should cover all the following activities:

1.Vaccine research and development for emerging pathogens.

2.Development of adaptable vaccine technologies.

3.Collaboration with stakeholders in epidemic preparedness.

This action is expected to engage with other relevant initiatives, such as the co-funded European Partnership for Pandemic Preparedness 473 and the European Vaccine Hub 474 .

With the grant from the European Union, CEPI will be able to award one or several grants to third parties through competitive calls for proposals. The call(s) will be issued to fund advanced pre-clinical as well as clinical research on new vaccines for the prevention of emerging and re-emerging infectious diseases. For this purpose this action is also expected to engage with HERA, and support the EU policy goals of scientific leadership in pharmaceutical research and development and strategic autonomy. Therefore, in its financing of third parties, this action should favour activities conducted in Member States or Associated Countries. Such activities may include early-phase clinical trials, and/or enabling activities, for instance the manufacturing of GMP-grade 475 batches of investigational products. The action is expected to incentivise the development of local expertise and strengthen regional scientific capacities in Member States and Associated Countries, in balance with the overarching need to prioritise scientific excellence as well as logistical and strategic considerations.

The expected recipients of the grant(s) issued by CEPI include research institutes, universities, small and medium-sized enterprises (SMEs) 476 as well as large companies, all active in research and innovation on new and improved vaccines.

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation to CEPI, as CEPI has been a key partner for implementing the common Union response to the COVID-19 epidemic.

Award criteria:

The criteria are described in General Annex D. The following exceptions apply: The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements:

The funding rate will be 70%.

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Financial support provided by CEPI to third parties is one of the primary activities of this action in order to be able to achieve its objectives as CEPI does not have the capacity to develop new medical countermeasures itself. The maximum amount to be granted to a third party is EUR 15 million. This is justified by the high cost of development for new vaccines, that reaches tens of millions of Euros 477 . However, if the objectives of the action would otherwise be impossible or overly difficult (and duly justified in the proposal) the maximum amount may be higher.

Legal entities:

Coalition for Epidemic Preparedness Innovations, Marcus Thranes gate 2, 0473 Oslo, Norway

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Programme co-fund action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Fourth Quarter of 2027

Indicative budget: EUR 34.40 million from the 2027 budget

5. Presidency event - Greece. Climate change and health - Aligning Research and Innovation for a resilient future (European and global perspectives)

Objective: This action will cover the organisation of a high-level conference by the Greek Presidency, focusing on Climate Change and Health. The primary objective of the proposed conference is to facilitate high-level dialogue among policymakers, researchers, industry leaders and civil society organisations on the interlinkages between climate change and health. The focus will be on understanding and addressing the impacts of climate change on human health, increasing climate adaptation and resilience and reducing the health sector's contribution to climate change. The conference aims to identify and propose integrated strategies for aligning research and innovation as well as funding to address the dual challenges posed by climate change and public health.

Scope: The interplay between climate change and human health represents one of the defining challenges of our time. The climate crisis is a health crisis with impacts at global level. Across Europe, the fastest-warming continent, heat and floods have caused devastating human and economic impact in recent years. The European Union has already demonstrated global leadership through the European Green Deal 478 , the EU Mission on Climate Adaptation, the “Strategy for European Life Sciences” 479 flagship on health and climate change and the EU Strategic Research and Innovation Agenda on Health and Climate Change 480 published in 2025. The Greek Presidency intends to reinforce the EU’s role as a driver of knowledge-based policy and international cooperation and advance this leadership by fostering dialogue and joint action on aligning research and innovation efforts to protect citizens’ health and wellbeing in a rapidly changing climate.

This forward-looking conference will take stock of the progress achieved by ongoing initiatives and serve as a pivotal platform for discussing pressing climate-related health issues, assessing the impacts of climate change on public health systems and evaluating innovative research and technological solutions, while addressing also the socio-economic dimensions of resilience. Emphasising collaboration across Europe and globally, it will encourage sharing of best practices, evidence, innovative technologies, and resources among stakeholders in public health, environmental science, and technology sectors. Discussions will focus on:

1.Advancing climate-health research excellence.

2.Integrating health considerations into climate adaptation and mitigation strategies.

3.Boosting climate neutrality and circularity in the healthcare sector.

4.Mobilising innovative technologies, nature-based solutions and social innovations.

5.Enhancing preparedness and responsiveness of public health systems.

Target audience:

1.EU policymakers and officials (EU institutions and agencies, ministries of research, health, and environment from EU Member States and Associated Countries).

2.Researchers and academic experts in environmental science, public health and innovation.

3.Innovators and industry stakeholders in climate and health sectors, industry representatives from pharmaceutical and technology sectors.

4.International organisations and health agencies (WHO, UNEP, IPCC, OECD).

5.Non-Governmental Organisations (NGOs) and civil society organisations focused on climate action and health, including youth and vulnerable community representatives.

6.Media representatives covering environmental and health issues.

Outline of key elements to be addressed by the conference:

1.Scientific evidence & risk assessment: Latest knowledge on vulnerabilities and health risk projections.

2.Policy coherence: Aligning EU, national, and global frameworks to address climate-health challenges.

3.Innovation pathways: Technological and social innovations for prevention, adaptation and mitigation.

4.Financing synergies: Coordinating funding instruments (e.g. Horizon Europe, EU4Health Programme (2021-2027) 481 , national budgets, global funds).

5.Equity & inclusion: Ensuring solutions are inclusive and socially equitable.

6.Global partnerships: Strengthening multilateral climate-health cooperation and coordination.

Expected Outcomes and Deliverables: The conference will provide a timely opportunity to consolidate knowledge, foster dialogue and chart a forward-looking action plan by:

1.Identifying actionable practices for integrating climate and health considerations into research and policy frameworks at national, European and global level.

2.Informing future research and regulatory frameworks that address knowledge gaps through coordinated approaches.

3.Fostering multi-stakeholder dialogue and creating synergies among academia, policymakers, industry, and civil society.

4.Facilitating EU-level policy discussions, supporting the European Green Deal, Horizon Europe programme, the “Strategy for European Life Sciences” and the European Health Union agenda 482 .

5.Promoting the uptake of research results and innovative solutions, by connecting developers with policymakers and end-users.

The outcomes will directly support EU strategies and ongoing initiatives on climate and health research while ensuring coherence with European and global agendas, maximising the impact of research and innovation for societal benefit. The conference will deliver an action plan delineating key research and innovation activities to address the climate change and health crisis.

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation to the legal entity identified below.

Award criteria:

The criteria are described in General Annex D. The following exceptions apply: The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Procedure:

The evaluation committee will be composed fully by representatives of EU institutions.

Legal and financial set-up of the Grant Agreements:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 483 .

The funding rate will be 100%.

Subcontracting is not restricted to a limited part of the action.

Legal entities:

General Secretariat for Research and Innovation, Ministry of Development, 14-18 Mesogeion Avenue, 11527, Athens, Greece

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: First Quarter of 2027

Indicative budget: EUR 0.30 million from the 2027 budget

6. European registry for human pluripotent stem cell lines

Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, project results are expected to contribute to the following expected outcome:

1.Allow researchers to be informed on stem cell lines.

Scope: The aim is to gather and make available detailed information on the different human Pluripotent Stem Cell (hPSC) lines derived in Europe and beyond, thereby also avoiding needless creation of new cell lines. This registry operates through an internet website that will continue to provide high quality data about the lines (e.g. cell characteristics), details regarding their source and contact information regarding their location. Further work will be done to ensure robustness of the infrastructure and sustainability of the resource.

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 24(3)(b) of the Horizon Europe Regulation to the legal entity that manages the European registry for hPSC lines.

Award criteria:

The criteria are described in General Annex D. The following exceptions apply: The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12.

Legal and financial set-up of the Grant Agreements:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 484 .

The funding rate will be 100%.

Subcontracting is not restricted to a limited part of the action.

Legal entities:

Charité - Universitätsmedizin Berlin, Anna-Louisa-Karsch-Straße 2, 10178 Berlin, Germany

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Fourth Quarter of 2027

Indicative budget: EUR 1.47 million from the 2027 budget

Other Instruments

1. External expertise

This action will support the use of appointed independent experts for the monitoring of running actions (grant agreement, grant decision, public procurement actions, financial instruments) funded under Horizon Europe and previous Framework Programmes for Research and Innovation, for ethics checks, for the evaluation of large actions annual work plans, as well as for compliance checks regarding the Gender Equality Plan eligibility criterion. A special allowance of EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest.

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative budget: EUR 1.95 million from the 2026 budget and EUR 1.95 million from the 2027 budget

2. External expertise in relation to EU research and innovation policy issues

This action will support the provision of independent expertise in support of the assessment, design, implementation, evaluation and valorisation of EU research and innovation policies in the areas currently in scope of the Health Cluster.

Individual experts will work on tasks such as, but not limited to: portfolio analysis of projects funded under Horizon Europe or previous European research and innovation programmes; analysis of the contribution of research results (at national, EU and/or international level) to EU policy objectives and emerging issues, including policy recommendations; analysis of the state-of-the-art at European and international level; participation in studies, conferences, events, symposia, etc, including the drafting of papers and reports on their conclusions; assistance for setting-up a research and innovation strategy for selected domains; policy recommendations and options assisting Commission services in elaborating evidence-based and scientifically sound policy proposals; assistance in the evaluation of calls for expression of interest; advice on the valorisation, communication, dissemination and exploitation of research results; identification of innovative solutions as well as potential gaps and synergies to be addressed by EU research and innovation policy; advice on promising technologies covered by European and nationally funded projects and on ways to stimulate synergies, etc.

In addition to individual experts, this action could provide for Commission expert groups.

A special allowance of maximum EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest.

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative budget: EUR 0.09 million from the 2026 budget and EUR 0.09 million from the 2027 budget

3. Mobilisation of research funds in case of Public Health Emergencies

Expected Outcome:

Proposals should set out a credible pathway to contributing to one or several expected impacts of destination: “Tackling diseases and reducing disease burden”.

Project results are expected to contribute to the following expected outcome: Allow the Union to respond to Public Health Emergencies.

Scope:

In case of a public health emergency 485 (such as a Public Health Emergency of International Concern (PHEIC) according to the World Health Organization, a public health emergency under Regulation (EU) 2022/2371 486 or under applicable national frameworks and regulations), funding will be mobilised for:

1.The award of grants without a call for proposals according to Article 198 (b) of the EU Financial Regulation 487 in exceptional and duly substantiated emergencies. At that time, the Funding & Tenders Portal will open a dedicated section where proposals can be submitted. This will be communicated to the National Contact Points. The invitation to apply for funding will be open to all eligible entities or be limited to targeted entities, taking into account the need to achieve the underlying objectives in a quick and efficient manner considering the exceptional circumstances; and/or

2.The award of additional funding for ongoing grant agreements funded through EU Framework Programmes for Research and Innovation to cover additional activities specifically linked to the public health emergency, in exceptional and duly substantiated emergencies. Providing such additional funding to ongoing EU Framework Programmes for Research and Innovation grants that can support pertinent short- and mid-term research efforts to confront the public health emergency will save valuable time and allow addressing the situation with the appropriate urgency. Restricted calls for expression of interest or proposals will develop such additional activities or add additional partners to existing EU Framework Programmes for Research and Innovation actions.

It is expected that quality-controlled data are shared in accordance with the FAIR 488 principles. The use of harmonised protocols in collaboration with other actors is recommended for this purpose.

The standard eligibility and admissibility criteria, evaluation criteria, thresholds, weighting for award criteria, maximum funding rate and conditions for providing financial support to third parties, are provided in the General Annexes.

The beneficiaries must comply with the public emergency related provisions listed in the General Annexes concerning the project implementation under Intellectual Property Rights (IPR), background and results, access rights and rights of use (article 16 and Annex 5) for the duration of the Public Health Emergency; and under Communication, dissemination, open science and visibility (article 17 and Annex 5) during the entire duration of the action and for four years after the end of the action.

The following derogations to the evaluation procedure described in General Annexes D and F apply to open invitations to submit applications:

In order to ensure a balanced portfolio covering responses to different aspects of the public health emergency, grants will be awarded to applications not only in order of ranking, but also to those projects that enhance the quality of the project portfolio through synergies between projects and avoidance of overlaps, provided that the applications attain all thresholds.

The action may also include justified derogations from the standard limits to financial support to third parties. Where applicable, the relevant grant agreement options will be applied.

The award will be without a call for proposals according to Article 198(b) of the Financial Regulation.

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant awarded without call for proposals according to Financial Regulation Article 198 (b)

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Will depend on the Public Health Emergency

Indicative budget: EUR 0.90 million from the 2026 budget and EUR 0.90 million from the 2027 budget

4. Studies, conferences, events and outreach activities

A number of specific contracts will be signed in order to: (i) support the dissemination and exploitation of project results; (ii) contribute to the definition of future challenge priorities; (iii) undertake citizen surveys such as Eurobarometers; (iv) carry out specific evaluations of programme parts; (v) support future European Research Area (ERA) policy actions; and (vi) organise conferences, events and outreach activities.

Subject matter of the contracts envisaged: studies, technical assistance, conferences, events and outreach activities.

Form of Funding: Procurement

Type of Action: Public procurement

Indicative timetable: 2026 and 2027

Indicative budget: EUR 1.01 million from the 2026 budget and EUR 1.00 million from the 2027 budget

5. Subscription to the Human Frontier Science Program Organization

An annual subscription to the international Human Frontier Science Program Organization (HFSPO) 489 will allow researchers from EU non-G7 Member States to fully benefit from the Human Frontier Science Program (HFSP), enable initiatives to help the affected scientific community in and from areas recently severely ravaged by conflict and/or war on European ground and contribute to the implementation of the Global Approach to Research and Innovation, Europe’s strategy for international cooperation in a changing world 490 .

Type of Action: Subscription action

Indicative timetable: 2026 and 2027

Indicative budget: EUR 7.04 million from the 2026 budget and EUR 7.18 million from the 2027 budget

Budget 491   492

Budget line(s)

2026 Budget (EUR million)

2027 Budget (EUR million)

Calls

HORIZON-HLTH-2026-01

471.60

from 01.020210

471.60

HORIZON-HLTH-2026-02

48.70

42.60

from 01.020210

48.70

42.60

HORIZON-HLTH-2026-03

30.00

33.00

from 01.020210

30.00

33.00

HORIZON-HLTH-2026-04

9.80

from 01.020210

9.80

HORIZON-HLTH-2027-01

331.60 493

from 01.020210

331.60

HORIZON-HLTH-2027-02-two-stage

186.60

from 01.020210

186.60

HORIZON-HLTH-2027-03

81.50

from 01.020210

81.50

Other actions

Grant awarded without a call for proposals according to Financial Regulation Article 198(e)

39.90

36.17

from 01.020210

39.90

36.17

Expert contract action

2.04

2.04

from 01.020210

2.04

2.04

Grant awarded without a call for proposals according to Financial Regulation Article 198

0.90

0.90

from 01.020210

0.90

0.90

Public procurement

1.01

1.00

from 01.020210

1.01

1.00

Subscription action

7.04

7.18

from 01.020210

7.04

7.18

Estimated total budget

610.99

722.59

(1)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/strategic-plan_en
(2)     https://commission.europa.eu/about/commission-2024-2029_en
(3)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(4)     https://data.consilium.europa.eu/doc/document/ST-15315-2024-INIT/en/pdf
(5)     https://health.ec.europa.eu/health-emergency-preparedness-and-response-hera/preparedness/medical-countermeasures-strategy_en
(6)     https://health.ec.europa.eu/publications/proposal-critical-medicines-act_en
(7)     https://cordis.europa.eu/project/id/101095654 , https://www.thcspartnership.eu
(8)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(9)     https://research-and-innovation.ec.europa.eu/document/download/47554adc-dffc-411b-8cd6-b52417514cb3_en
(10)     https://cordis.europa.eu/project/id/101156595 , https://erdera.org
(11)     https://cordis.europa.eu/project/id/101226682 , https://beready4pandemics.eu
(12)    In March 2024, the Commission adopted the Strategic Technologies for Europe Platform (STEP) to boost investments in critical technologies in Europe: clean and resource efficient technologies, digital and deep innovation technologies and biotechnologies. STEP will mobilise funding from existing EU programmes to support the development and manufacturing of these critical technologies, while safeguarding and strengthening the respective value chains, as well as associated services and skills critical for and specific to the development and manufacturing of the final products.
(13)     https://strategic-technologies.europa.eu/investors_en
(14)    COM(2021) 252 final
(15)    JOIN(2021) 30 final
(16)    E.g. the EU4Health Programme, the Digital Europe Programme, the European Regional Development Fund (ERDF), including Interreg, the European Social Fund (ESF+), the Structural Reform Support Programme (SRSP), the Just Transition Fund (JTF), the European Maritime, Fisheries and Aquaculture Fund (EMFAF), the European Agricultural Fund for Rural Development (EAFRD), the European Defence Fund (EDF) or InvestEU.
(17)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(18)     https://digital-strategy.ec.europa.eu/en/activities/digital-programme
(19)    Synergies between Horizon Europe and ERDF programmes (including Interreg): https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=oj:JOC_2022_421_R_0003
(20)     https://health.ec.europa.eu/system/files/2022-02/eu_cancer-plan_en_0.pdf
(21)    The European Cancer Information System (ECIS - https://ecis.jrc.ec.europa.eu ) and the European Network of Cancer Registries (ENCR - https://www.encr.eu )
(22)    European Commission Initiatives on Breast and Colorectal Cancer: https://healthcare-quality.jrc.ec.europa.eu
(23)    European Cancer Inequalities Registry: https://cancer-inequalities.jrc.ec.europa.eu
(24)    European Platform on Rare Disease Registration (EU RD Platform - https://eu-rd-platform.jrc.ec.europa.eu/_en ) - for rare cancers
(25)    Health Promotion and Disease Prevention Knowledge Gateway Horizon Europe: https://knowledge4policy.ec.europa.eu/health-promotion-knowledge-gateway_en
(26)     https://www.go-fair.org/fair-principles
(27)     https://faircookbook.elixir-europe.org/content/home.html
(28)     https://www.openaire.eu/how-to-make-your-data-fair
(29)     https://ri-portfolio.esfri.eu
(30)     https://www.eric-forum.eu/the-eric-landscape
(31)     https://research-and-innovation.ec.europa.eu/strategy/strategy-2020-2024/our-digital-future/open-science/european-open-science-cloud-eosc_en
(32)    European space technology based earth observation, positioning, navigation and timing services provided by: Copernicus, the European Union's Earth observation programme https://www.copernicus.eu/en/copernicus-services ; Galileo, the European Global Satellite Navigation System (GNSS) https://www.gsc-europa.eu/galileo/services/galileo-initial-services ; and the European Geostationary Navigation Overlay Service (EGNOS) https://www.euspa.europa.eu/eu-space-programme/egnos
(33)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A32014R0536
(34)     https://euclinicaltrials.eu
(35) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(36)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(37) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(38)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(39) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(40)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(41) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(42)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(43) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(44)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(45)    Of which EUR 10.00 million from the 'Climate, Energy and Mobility' budget.
(46) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(47)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(48) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(49)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(50)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/strategic-plan_en
(51)    “Health at a Glance: Europe 2024”, available from https://health.ec.europa.eu/state-health-eu/health-glance-europe_en
(52)     https://www.who.int/europe/news-room/fact-sheets/item/disability The WHO European Region comprises 53 countries, covering a vast geographical region from the Atlantic to the Pacific oceans.
(53)     https://commission.europa.eu/about/commission-2024-2029_en
(54)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(55)     https://research-and-innovation.ec.europa.eu/strategy/strategy-2020-2024/our-digital-future/open-science/european-open-science-cloud-eosc_en
(56)    Communication from the European Commission on the European care strategy, COM(2022) 440, 7.9.2022
(57)    Communication from the European Commission on enabling the digital transformation of health and care in the Digital Single Market; empowering citizens and building a healthier society, COM(2018) 233, 25.4.2018
(58)    Entities assessed as “high-risk suppliers”, are currently set out in the second report on Member States’ progress in implementing the EU toolbox on 5G cybersecurity of 2023 (NIS Cooperation Group, Second report on Member States’ progress in implementing the EU Toolbox on 5G Cybersecurity, June 2023) and the related Communication on the implementation of the 5G cybersecurity toolbox of 2023 (Communication from the Commission: Implementation of the 5G cybersecurity Toolbox, Brussels, 15.6.2023 C(2023) 4049 final).
(59)    EMA definition: “Real-World Data are routinely collected data relating to patient health status or the delivery of healthcare from a variety of sources other than traditional clinical trials (e.g. claims databases, hospital data, electronic health records, registries, mhealth data, etc.)”.
(60)    The prevalence of a disease is the number of cases in a defined population at a specified point in time. See https://iris.who.int/bitstream/handle/10665/36838/9241544465.pdf
(61)    See definition of FAIR data in the introduction to this Work Programme part.
(62)    General Data Protection Regulation: https://commission.europa.eu/law/law-topic/data-protection_en , https://gdpr-info.eu
(63)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(64)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(65)     https://scicommcentre.eu
(66)     https://cordis.europa.eu/project/id/101095230
(67)    The European Competence Centre for Science Communication will be fully established by March 2027. Its development is being undertaken with a strong basis of co-creation amongst multiple stakeholders by the COALESCE project
(68)     https://cordis.europa.eu/article/id/442429-science-communication-empowering-citizens-in-the-public-discussion-of-science
(69)     https://cordis.europa.eu/article/id/450170-ethics-and-integrity-building-bridges-for-trust-and-excellence-in-research-and-innovation
(70)     https://www.who.int/publications/i/item/9789241550208
(71)     https://knowledge4policy.ec.europa.eu/participatory-democracy_en
(72)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(73)    Persons with disabilities include those who have long-term physical, mental, intellectual or sensory impairments which in interaction with various barriers may hinder their full and effective participation in society on an equal basis with others (Art. 1 of the Convention on the Rights of Persons with Disabilities - https://www.ohchr.org/en/instruments-mechanisms/instruments/convention-rights-persons-disabilities ).
(74)     https://op.europa.eu/en/publication-detail/-/publication/3e1e2228-7c97-11eb-9ac9-01aa75ed71a1/language-en
(75)    An older person is defined by the United Nations as a person who is over 60 years of age.
(76)    If proposals concern drug addiction, they are encouraged to liaise with the EU Drugs Agency.
(77)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=OJ:C_202407188
(78)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(79)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(80)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/strategic-plan_en
(81)     https://op.europa.eu/en/publication-detail/-/publication/616cce9c-39e5-11f0-8a44-01aa75ed71a1
(82)     https://commission.europa.eu/about/commission-2024-2029_en
(83)    Broad focus area i to iii, as given in the scope of this topic.
(84)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(85)    See definition of FAIR data in the introduction to this Work Programme part.
(86)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(87)     https://research-and-innovation.ec.europa.eu/strategy/strategy-2020-2024/our-digital-future/open-science/european-open-science-cloud-eosc_en
(88)    As defined by the World Bank, https://www.worldbank.org
(89)     https://research-and-innovation.ec.europa.eu/research-area/health/environment-climate-and-health_en
(90)     https://climate-adapt.eea.europa.eu/en/observatory
(91)     https://climate-health.eu
(92)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(93)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(94)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(95)     https://research-and-innovation.ec.europa.eu/research-area/health/environment-climate-and-health_en
(96)     https://climate-adapt.eea.europa.eu/en/observatory
(97)     https://climate-health.eu
(98)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(99)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(100)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(101)     https://ipchem.jrc.ec.europa.eu
(102)    See definition of FAIR data in the introduction to this Work Programme part.
(103)    EMA definition: “Real-World Data are routinely collected data relating to patient health status or the delivery of healthcare from a variety of sources other than traditional clinical trials (e.g. claims databases, hospital data, electronic health records, registries, mhealth data, etc.)”.
(104)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(105)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(106)     https://www.humanexposome.eu
(107)     https://humanexposome.net
(108)     https://www.icos-cp.eu/about/organisation-governance/icos-eric
(109)     https://eirene.eu
(110)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(111)     https://bio.tools/t?domain=exposome
(112)     https://data-catalogue.molgeniscloud.org/catalogue/catalogue
(113)     https://research-and-innovation.ec.europa.eu/research-area/health/environment-climate-and-health_en
(114)     https://climate-adapt.eea.europa.eu/en/observatory
(115)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(116)    For digital technologies concerned, appropriate measures for the security of the communications between the intended parties should be considered, in particular based on the use of post-quantum cryptography.
(117)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(118)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/eu-missions-horizon-europe/adaptation-climate-change_en
(119)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52023DC0457&qid=1693304388860
(120)    Initially established by MIP4Adapt ( https://climate-adapt.eea.europa.eu/en/mission/the-mission/about-mip4adapt , https://fedarene.org/project/mip4adapt ) and extended under the contract CINEA/2025/OP/0014.
(121)     https://climate-adapt.eea.europa.eu/en/mission/community-of-practice
(122)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/strategic-plan_en
(123)    Preventive healthcare expenditure as a share of the current expenditure on healthcare: https://ec.europa.eu/eurostat/statistics-explained/index.php?title=File:Preventive_healthcare_expenditure_as_a_share_of_current_expenditure_on_healthcare,_2021_(%25)_HCE2024.png
(124)     https://commission.europa.eu/about/commission-2024-2029_en
(125)     https://health.ec.europa.eu/health-emergency-preparedness-and-response-hera/preparedness/medical-countermeasures-strategy_en
(126)     https://health.ec.europa.eu/publications/proposal-critical-medicines-act_en
(127)     https://cordis.europa.eu/project/id/101156595 , https://erdera.org
(128)     https://cordis.europa.eu/project/id/101226682 , https://beready4pandemics.eu
(129)     https://eic.ec.europa.eu
(130)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(131)     https://www.who.int/publications/i/item/9789241506236
(132)     https://www.who.int/publications/m/item/implementation-roadmap-2023-2030-for-the-who-global-action-plan-for-the-prevention-and-control-of-ncds-2023-2030
(133)    Disability-adjusted life year (DALY) is a quantitative indicator of overall disease burden, expressed as the number of years lost due to ill-health, disability or early death.
(134)    WHO global action plan on antimicrobial resistance, 2015
(135)    EU One Health Action Plan against AMR, 2017
(136)     https://www.ema.europa.eu/en/news/one-health-joint-framework-action-published-five-eu-agencies
(137)    Entities assessed as “high-risk suppliers”, are currently set out in the second report on Member States’ progress in implementing the EU toolbox on 5G cybersecurity of 2023 (NIS Cooperation Group, Second report on Member States’ progress in implementing the EU Toolbox on 5G Cybersecurity, June 2023) and the related Communication on the implementation of the 5G cybersecurity toolbox of 2023 (Communication from the Commission: Implementation of the 5G cybersecurity Toolbox, Brussels, 15.6.2023 C(2023) 4049 final).
(138)    There is no universal definition of youth and young adults. For the purpose of this topic, we follow the WHO definition of young adult a person aged 15-24: https://www.who.int/southeastasia/health-topics/adolescent-health
(139)     https://health.ec.europa.eu/system/files/2020-02/2018_healthatglance_rep_en_0.pdf
(140)     https://www.europarl.europa.eu/RegData/etudes/BRIE/2023/751416/EPRS_BRI(2023)751416_EN.pdf
(141)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52023DC0298
(142)    ICD11, Chapter 6: https://icd.who.int/browse/2025-01/mms/en#334423054
(143)     https://www.ebrains.eu
(144)     https://www.eurobioimaging.eu
(145)    Projects funded under topics HORIZON-HLTH-2024-STAYHLTH-01-02-two-stage: "Towards a holistic support to children and adolescents’ health and care provisions in an increasingly digital society" and HORIZON-HLTH-2022-STAYHLTH-01-01-two-stage: "Boosting mental health in Europe in times of change".
(146)     https://www.brainhealth-partnership.eu
(147)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(148)    See definition of FAIR data in the introduction to this Work Programme part.
(149)    General Data Protection Regulation: https://commission.europa.eu/law/law-topic/data-protection_en , https://gdpr-info.eu
(150)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(151)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(152)    For pharmacological interventions: phase 1 and phase 2 clinical trials.
(153)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(154)    See definition of FAIR data in the introduction to this Work Programme part.
(155)    ORCHESTRA data portal: https://orchestra-cohort.eu/data-portal , Pathogens portal cohorts browser: https://www.pathogensportal.org/cohorts
(156)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(157)     https://research-and-innovation.ec.europa.eu/strategy/strategy-2020-2024/our-digital-future/open-science/european-open-science-cloud-eosc_en
(158)     https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/horizon-hlth-2021-corona-01-02 , https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/horizon-hlth-2023-disease-03-07 and https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/horizon-hlth-2025-01-disease-07
(159)    The details of these joint activities will be defined during the grant agreement preparation phase. Applicants should plan the necessary budget to cover those activities without the prerequisite to define concrete common actions at this stage.
(160)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(161)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(162)    Virus i to viii, as given in the scope of this topic.
(163)     https://health.ec.europa.eu/health-emergency-preparedness-and-response-hera/preparedness/medical-countermeasures-strategy_en
(164)     https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(165)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(166)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(167)     https://isidore-project.eu
(168)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(169)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(170)    As defined by the World Bank, https://www.worldbank.org
(171)     https://www.gacd.org
(172)     https://iris.who.int/bitstream/handle/10665/91758/9789241506212_eng.pdf
(173)    In this context, non-healthcare settings can include for instance: workplaces; schools, universities and other education venues (including pre-schools, nursery, etc.); faith-based communities, places of worship and traditional healers; recreation and sports clubs, fitness centres, swimming pools; prisons; communities (geographic and/or of identity) and families; community pharmacies; theatres, community spaces; retirement homes and care homes; homeless shelters; markets, malls, commercial settings; barbers, hairdressers and beauty salons; urban environments, parks, transportation (the list is not exhaustive).
(174)    Research proposals might explore implementation, outcomes and impact of context relevant strategies to implement evidence-based interventions or initiatives including (though not limited to):i) Non-health sector policy introduction, to tackle relevant social and/or structural determinants of NCDs; ii) Strategies to expand screening for NCDs and their risk factors in community, school, workplace, faith-based settings (e.g. Human Papillomavirus - HPV screening, blood pressure monitoring, blood sugar testing); ii) Partnered strategies to prevent NCDs in the community (e.g. educational campaigns, changes to school or work environments, promotion/delivery of healthy food choice and diet, opportunities for increased physical activity, strategies to support tobacco cessation and alcohol cessation); iv) Cost effective, patient centred treatment and management of NCDs in the community (e.g. mental health support, community medicine purchasing clubs, self-management groups); v) Non-health sector policy introduction e.g. environmental policy or practices (e.g. improvements to transport systems, public infrastructure) and the potential co-benefits on health; vi) Digital interventions e.g. for patient or care giver support, such as use of Artificial Intelligence for Patient support or to promote prevention messages on Chronic Disease Risk Factors).
(175)    Focus on populations facing extreme vulnerabilities, such as individuals or communities living in informal settlements, post-disaster settings, or in situations of homelessness is encouraged (though not required).
(176)    The following types of proposals are not in the scope of this topic: i) proposals with the primary aim of informing the development and/or selection of an intervention for a given context, where the implementation component will be explored in a future project (i.e. standalone feasibility projects);ii) epidemiological cohorts; iii) etiological work, mechanistic, or epidemiological research, unless an essential component of a focused study to develop implementation research approaches; iv) clinical trials, validation studies, or intervention efficacy studies for a new or established pharmacological agent or behavioural intervention.
(177)    Examples of frameworks include (this list is not exclusive): i) Consolidated Framework for Implementation Research (CFIR); ii) the context enhanced (RE-AIM) Reach, Effectiveness, Adoption, Implementation, Maintenance); iii) Practical Robust Implementation and Sustainability Model (PRISM) frameworks; iv) Framework for Developing and Evaluating Complex Interventions (MRC & NIHR).
(178)     https://pmc.ncbi.nlm.nih.gov/articles/PMC3731143 and https://pmc.ncbi.nlm.nih.gov/articles/PMC6779135
(179)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(180)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(181)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(182)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(183)    European Union takes action for the cardiovascular health of its 440 million people - EACH: https://www.cardiovascular-alliance.eu/european-union-takes-action-for-the-cardiovascular-health-of-its-440-million-people
(184)    Gender Disparities in Cardiovascular Disease and Their Management: A Review - PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC11148660
(185)    Political declaration of the 3rd High-Level Meeting of the General Assembly on the Prevention and Control of Non-Communicable Diseases : resolution adopted by the General Assembly: https://digitallibrary.un.org/record/1648984?v=pdf
(186)    See definition of FAIR data in the introduction to this Work Programme part.
(187)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(188)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(189)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(190)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(191)    See definition of FAIR data in the introduction to this Work Programme part.
(192)    Consortium which was awarded the grant under topic HORIZON-HLTH-2023-DISEASE-07-01: “European Partnership on Rare Diseases”.
(193)     https://health.ec.europa.eu/publications/communication-commission-com2014-215-final_en
(194)     https://health.ec.europa.eu/publications/commission-communication-com-2018-233_en
(195)     https://www.consilium.europa.eu/en/press/press-releases/2024/06/21/european-health-union-council-calls-on-commission-to-keep-health-as-a-priority
(196)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(197)     https://health.ec.europa.eu/medicinal-products/pharmaceutical-strategy-europe_en
(198)     https://eur-lex.europa.eu/eli/dir/2011/24/oj/eng in particular articles 12 and 13 respectively on European Reference Networks (ERNs) and rare diseases
(199)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(200)     https://erdera.org/strategic-research-innovation-agenda-sria
(201)    The relevant European research infrastructures in the area of health should be exploited for available services, expertise and digital tools for dataset creation, standardisation, data discovery, secure access, management, visualisation, harmonisation, analysis and other functions as appropriate. The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(202)     https://irdirc.org
(203)     https://ec.europa.eu/transparency/expert-groups-register/screen/expert-groups/consult?lang=en&groupId=104872&fromMeetings=true&meetingId=59543
(204)     https://commission.europa.eu/strategy-and-policy/priorities-2019-2024/promoting-our-european-way-life/european-health-union/health-crisis-preparedness_en
(205)    EU Global Health Strategy: Better Health for All in a Changing World - European Commission: https://health.ec.europa.eu/publications/eu-global-health-strategy-better-health-all-changing-world_en
(206)    Consortium which was awarded the grant under topic HORIZON-HLTH-2024-DISEASE-12-01: “European Partnership for Pandemic Preparedness”.
(207)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex:52025JC0130
(208)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(209)     https://health.ec.europa.eu/funding/eu4health-programme-2021-2027-vision-healthier-european-union_en , https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32021R0522
(210)     https://digital-strategy.ec.europa.eu/en/activities/digital-programme
(211)     https://beready4pandemics.eu/sria
(212)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(213)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(214)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(215)     https://research-and-innovation.ec.europa.eu/strategy/strategy-2020-2024/our-digital-future/open-science/european-open-science-cloud-eosc_en
(216)    See definition of FAIR data in the introduction to this Work Programme part.
(217)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(218)    See the European Virtual Human Twins Initiative: https://digital-strategy.ec.europa.eu/en/policies/virtual-human-twins
(219)    European Union takes action for the cardiovascular health of its 440 million people - EACH: https://www.cardiovascular-alliance.eu/european-union-takes-action-for-the-cardiovascular-health-of-its-440-million-people
(220)     https://data.consilium.europa.eu/doc/document/ST-15315-2024-INIT/en/pdf
(221)     https://digital-strategy.ec.europa.eu/en/policies/1-million-genomes
(222)    Farinha, J., Nagy, O., Bailey, G., Mochan, A., Polvora, A. et al., Embodying the Future - Horizon scanning for emerging technologies and breakthrough innovations in the field of human-like AI systems, Publications Office of the European Union, Luxembourg, 2025, https://publications.jrc.ec.europa.eu/repository/handle/JRC143535
(223)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(224)     https://digital-strategy.ec.europa.eu/en/activities/digital-programme
(225)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(226)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(227)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(228)    See definition of FAIR data in the introduction to this Work Programme part.
(229)    For pharmacological interventions: phase 1 and/or phase 2 clinical trials.
(230)    Applicants may address any mono- or combinatorial pharmacological and/or non-pharmacological interventions.
(231)    Other diseases are not within the scope of this topic.
(232)    Comparative effectiveness studies are not within the scope of this topic.
(233)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(234)    For digital technologies concerned, appropriate measures for the security of the communications between the intended parties should be considered, in particular based on the use of post-quantum cryptography.
(235)     https://digital-strategy.ec.europa.eu/en/policies/virtual-human-twins
(236)    For instance BBMRI, ELIXIR, EU-OPENSCREEN, ECRIN, EATRIS, etc.
(237)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(238)    EMA definition: “Real-World Data are routinely collected data relating to patient health status or the delivery of healthcare from a variety of sources other than traditional clinical trials (e.g. claims databases, hospital data, electronic health records, registries, mhealth data, etc.)”.
(239)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(240)    Proposals should include a budget for the attendance to regular joint meetings and may consider covering the costs of any other potential joint activities without the prerequisite to detail concrete joint activities at this stage. The details of these joint activities will be defined during the grant agreement preparation phase.
(241)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(242)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(243)    Virus/group of viruses i to vi, as given in the scope of this topic.
(244)     https://health.ec.europa.eu/health-emergency-preparedness-and-response-hera/preparedness/medical-countermeasures-strategy_en
(245)     https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(246)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(247)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(248)     https://isidore-project.eu
(249)     https://cordis.europa.eu/project/id/101226682 , https://beready4pandemics.eu
(250)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(251)    Flavivirus i to vi, as given in the scope of this topic.
(252)     https://health.ec.europa.eu/health-emergency-preparedness-and-response-hera/preparedness/medical-countermeasures-strategy_en
(253)     https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(254)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(255)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(256)     https://isidore-project.eu
(257)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(258)    Virus i to vi, as given in the scope of this topic.
(259)     https://health.ec.europa.eu/health-emergency-preparedness-and-response-hera/preparedness/medical-countermeasures-strategy_en
(260)     https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(261)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(262)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(263)     https://isidore-project.eu
(264)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(265)    Pathogen i to vi, as given in the scope of this topic.
(266)     https://www.who.int/publications/i/item/9789240093461
(267)     https://health.ec.europa.eu/health-emergency-preparedness-and-response-hera/preparedness/medical-countermeasures-strategy_en
(268)     https://health.ec.europa.eu/publications/proposal-critical-medicines-act_en
(269)     https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(270)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(271)     https://cordis.europa.eu/project/id/101217154 , https://ohamr.eu
(272)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(273)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(274)    As defined by the World Bank, https://www.worldbank.org
(275)     https://www.gacd.org
(276)     https://iris.who.int/bitstream/handle/10665/91758/9789241506212_eng.pdf
(277)     https://www.taylorfrancis.com/chapters/oa-edit/10.4324/9781003306689-20/social-determinants-health-ncds-ruth-bell-jaime-miranda-jean-woo-michael-marmot
(278)     https://data.unicef.org/topic/child-health/noncommunicable-diseases/
(279)    Focus on populations facing extreme vulnerabilities, such as individuals or communities living in informal settlements, post-disaster settings, or in situations of homelessness is encouraged (though not required).
(280)    The following types of proposals are not in the scope of this topic: i) proposals with the primary aim of informing the development and/or selection of an intervention for a given context, where the implementation component will be explored in a future project (i.e. standalone feasibility projects); ii) epidemiological cohorts; iii) etiological work, mechanistic, or epidemiological research, unless an essential component of a focused study to develop implementation research approaches; iv) clinical trials, validation studies, or intervention efficacy studies for a new or established pharmacological agent or behavioural intervention.
(281)    Examples of frameworks include (this list is not exclusive): i) Consolidated Framework for Implementation Research (CFIR); ii) the context enhanced (RE-AIM) Reach, Effectiveness, Adoption, Implementation, Maintenance); iii) Practical Robust Implementation and Sustainability Model (PRISM) frameworks; iv) Framework for Developing and Evaluating Complex Interventions (MRC & NIHR).
(282)     https://pmc.ncbi.nlm.nih.gov/articles/PMC3731143 and https://pmc.ncbi.nlm.nih.gov/articles/PMC6779135
(283)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(284)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(285)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(286)    See definition of FAIR data in the introduction to this Work Programme part.
(287)    Rare diseases, as defined by the European Union Regulation on Orphan Medicinal Products (1999), being a disease that affects not more than 1 person per 2000 in the European population ( https://www.orpha.net/ ).
(288)    For pharmacological-based interventions: phase 1 and/or phase 2 clinical trials.
(289)    Generative AI is a type of AI technology that can generate various forms of new content such as text, images, sounds, and even code, such as for programming or gene sequencing ( https://ec.europa.eu/newsroom/dae/redirection/document/101621 ).
(290)     https://www.eurobioimaging.eu
(291)     https://gdi.onemilliongenomes.eu
(292)     https://ecrin.org
(293)     https://eatris.eu
(294)     https://www.ebrains.eu
(295)     https://www.bbmri-eric.eu
(296)    Consult databases e.g. CORDIS ( https://cordis.europa.eu ) & the JPND Research Database ( https://neurodegenerationresearch.eu/search-our-database ).
(297)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(298)     https://www.brainhealth-partnership.eu
(299)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(300)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/strategic-plan_en
(301)    Communication from the European Commission on the European care strategy, COM(2022) 440, 7.9.2022
(302)    Communication from the European Commission on enabling the digital transformation of health and care in the Digital Single Market; empowering citizens and building a healthier society, COM(2018) 233, 25.4.2018
(303)     https://employment-social-affairs.ec.europa.eu/policies-and-activities/european-pillar-social-rights-building-fairer-and-more-inclusive-european-union_en
(304)    Commission Communication on Artificial Intelligence for Europe; COM(2018) 237 final: https://digital-strategy.ec.europa.eu/en/policies/european-approach-artificial-intelligence ; https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=COM:2018:237:FIN
(305)     https://climate.ec.europa.eu/eu-action/adaptation-climate-change/eu-adaptation-strategy_e
(306)     https://health.ec.europa.eu/medicinal-products/pharmaceutical-strategy-europe_en
(307)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(308)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(309)     https://commission.europa.eu/strategy-and-policy/priorities-2019-2024/european-green-deal_en
(310)     https://commission.europa.eu/about/commission-2024-2029_en
(311)     https://commission.europa.eu/topics/eu-competitiveness_en
(312)     https://eic.ec.europa.eu
(313)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(314)    Entities assessed as “high-risk suppliers”, are currently set out in the second report on Member States’ progress in implementing the EU toolbox on 5G cybersecurity of 2023 (NIS Cooperation Group, Second report on Member States’ progress in implementing the EU Toolbox on 5G Cybersecurity, June 2023) and the related Communication on the implementation of the 5G cybersecurity toolbox of 2023 (Communication from the Commission: Implementation of the 5G cybersecurity Toolbox, Brussels, 15.6.2023 C(2023) 4049 final).
(315)     https://research-and-innovation.ec.europa.eu/strategy/support-policy-making/shaping-eu-research-and-innovation-policy/new-european-innovation-agenda/innovation-procurement/horizon-europe-funding-pcp-and-ppi_en For PPI executed by a group of procurers, the lead procurer should coordinate the preparation and implementation of one joint or several coordinated public procurements of innovative solutions, based on common specifications defined jointly by the buyers’ group. Each PPI should focus on one concrete need identified as a common challenge that requires the deployment of innovative solutions. Projects that aim to implement a PPI should contain a preparation and execution stage.
(316)    European Pillar of Social Rights: https://employment-social-affairs.ec.europa.eu/european-pillar-social-rights-20-principles_en
(317)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(318)     https://integratedcarefoundation.org/nine-pillars-of-integrated-care See also diagram: https://cordis.europa.eu/docs/results/h2020/634/634288_PS/001-eur-selfie2020-infographic-implementation.png and relevant corresponding article: https://www.sciencedirect.com/science/article/pii/S0277953621000605?via%3Dihub
(319)     https://health.ec.europa.eu/medicinal-products/personalised-medicine_en
(320)    For digital technologies concerned, appropriate measures for the security of the communications between the intended parties should be considered, in particular based on the use of post-quantum cryptography.
(321)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(322)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(323)     https://www.jadecare.eu
(324)     https://www.xt-ehr.eu
(325)     https://myhealthmyhands.eu
(326)     https://cordis.europa.eu/project/id/101095654 , https://www.thcspartnership.eu
(327)     https://cordis.europa.eu/project/id/101137129 , https://www.eppermed.eu
(328)     https://cordis.europa.eu/project/id/101156595 , https://erdera.org
(329)    Definition of low-value care from the Report by the Expert Group on Health Systems Performance Assessment: “From a health system perspective, low-value care encompasses overuse, misuse and underuse of healthcare services (for example, prevention, diagnostics, treatment, medication). Overuse and/or misuse comprise the delivery of harmful, ineffective, inappropriate, or not cost-effective healthcare services. Underuse refers to healthcare services not provided or used despite being necessary. Low-value care can lead to negative consequences for patients, their caregivers, the healthcare workforce, the health system as a whole and the wider environment.”
(330)    OECD (2017), Tackling Wasteful Spending on Health, OECD Publishing, Paris. http://dx.doi.org/10.1787/9789264266414-en
(331)    Report by the Expert Group on Health Systems Performance Assessment: “Identifying, Measuring And Reducing Low-Value Care In The Context Of Health System Performance Assessment”. https://health.ec.europa.eu/publications/identifying-measuring-and-reducing-low-value-care-context-health-system-performance-assessment_en
(332)     https://health.ec.europa.eu/health-systems-performance-assessment_en
(333)    Some proposals may not need to conduct clinical studies to achieve the objectives.
(334)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(335)     https://cordis.europa.eu/project/id/101095654 , https://www.thcspartnership.eu
(336)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(337)    Some proposals may not need to conduct clinical studies to achieve the objectives.
(338)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(339)    Consortium which was awarded the grant under topic HORIZON-HLTH-2023-CARE-08-01: “European Partnership on Personalised Medicine”.
(340)     https://www.ema.europa.eu/en/glossary-terms/medicinal-product
(341)    Old age is often defined as starting around 60 or 65 years of age.
(342)    Emma L. M. Jennings et al., In-hospital adverse drug reactions in older adults; prevalence, presentation and associated drugs - a systematic review and meta-analysis, Age and Ageing 2020; 49: 948-958 doi: 10.1093/ageing/afaa188
(343)     https://www.ema.europa.eu/en/documents/report/report-joint-ec-hma-ema-multi-stakeholder-workshop-pharmacogenomics-24-september-2024_en.pdf
(344)     https://www.ema.europa.eu/en/pharmaceutical-development-medicines-use-older-population-scientific-guideline
(345)     https://cpicpgx.org/guidelines
(346)     https://cordis.europa.eu/project/id/101137129 , https://www.eppermed.eu
(347)     https://cordis.europa.eu/project/id/101095654 , https://www.thcspartnership.eu
(348)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(349)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(350)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/strategic-plan_en
(351)     https://commission.europa.eu/about/commission-2024-2029_en
(352)    EMA definition: “Real-World Data are routinely collected data relating to patient health status or the delivery of healthcare from a variety of sources other than traditional clinical trials (e.g. claims databases, hospital data, electronic health records, registries, mhealth data, etc.)”.
(353)    Commission Communication on Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU; COM(2024) 137 final: https://research-and-innovation.ec.europa.eu/document/download/47554adc-dffc-411b-8cd6-b52417514cb3_en
(354)    Commission Communication on Artificial Intelligence for Europe; COM(2018) 237 final: https://digital-strategy.ec.europa.eu/en/policies/european-approach-artificial-intelligence ; https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=COM:2018:237:FIN
(355)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(356)     https://eic.ec.europa.eu
(357)    Commission Communication on the digital transformation of health and care; COM(2018) 233 final
(358)    Entities assessed as “high-risk suppliers”, are currently set out in the second report on Member States’ progress in implementing the EU toolbox on 5G cybersecurity of 2023 (NIS Cooperation Group, Second report on Member States’ progress in implementing the EU Toolbox on 5G Cybersecurity, June 2023) and the related Communication on the implementation of the 5G cybersecurity toolbox of 2023 (Communication from the Commission: Implementation of the 5G cybersecurity Toolbox, Brussels, 15.6.2023 C(2023) 4049 final).
(359)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(360)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(361)    See definition of FAIR data in the introduction to this Work Programme part.
(362)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(363)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(364)     https://joint-research-centre.ec.europa.eu/projects-and-activities/reference-and-measurement/european-union-reference-laboratories/eu-reference-laboratory-alternatives-animal-testing-eurl-ecvam_en
(365)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(366)    Projects that have not been completed before the submission deadline.
(367)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(368)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(369)    Commission Recommendation on critical technology areas for the EU's economic security for further risk assessment with Member States: https://defence-industry-space.ec.europa.eu/system/files/2023-10/C_2023_6689_1_EN_annexe_acte_autonome_part1_v9.pdf
(370)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(371)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(372)    Replacement, Reduction, Refinement: https://nc3rs.org.uk/who-we-are/3rs
(373)    Proposal for a Council Recommendation on the European Research Area Policy Agenda 2025-2027: https://european-research-area.ec.europa.eu/documents/proposal-council-recommendation-european-research-area-policy-agenda-2025-2027
(374)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(375)     https://strategic-technologies.europa.eu/about/step-seal_en
(376)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(377)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(378)    Committee for Advanced Therapies (CAT) quarterly highlights and approved ATMPs Feb-May 2025: https://www.ema.europa.eu/en/documents/committee-report/cat-quarterly-highlights-approved-atmps-may-2025_en.pdf
(379)    The future of European competitiveness, Mario Draghi: https://commission.europa.eu/topics/eu-competitiveness/draghi-report_en
(380)    Advanced Therapy Medicinal Products - EATRIS: https://eatris.eu/atmp
(381)    Good Manufacturing Practices: https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(382)     https://cordis.europa.eu/project/id/820292
(383)     https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/how-to-participate/org-details/999999999/project/101137206/program/43108390/details , https://cordis.europa.eu/project/id/101137206
(384)     https://cordis.europa.eu/project/id/101161301
(385)     https://cordis.europa.eu/project/id/945393
(386)     https://cordis.europa.eu/project/id/101156595 , https://erdera.org
(387)     https://cordis.europa.eu/project/id/101137129 , https://www.eppermed.eu
(388)     http://www.ihi.europa.eu
(389)    See definition as in the Strategic Research and Innovation Agenda of the Innovative Health Initiative Joint Undertaking: http://www.ihi.europa.eu/sites/default/files/uploads/Documents/About/IHI_SRIA_ApprovedJan22.pdf
(390)    EMA definition: “Real-World Data are routinely collected data relating to patient health status or the delivery of healthcare from a variety of sources other than traditional clinical trials (e.g. claims databases, hospital data, electronic health records, registries, mhealth data, etc.)”.
(391)    See introduction to this Work Programme part as well as the Ethics Guidelines for Trustworthy AI, published by the European Commission’s High Level Expert Group on Artificial Intelligence https://digital-strategy.ec.europa.eu/en/library/ethics-guidelines-trustworthy-ai and the Ethics by Design and Ethics of Use Approaches for Artificial Intelligence https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ethics-by-design-and-ethics-of-use-approaches-for-artificial-intelligence_he_en.pdf
(392)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(393)    General Data Protection Regulation: https://commission.europa.eu/law/law-topic/data-protection_en , https://gdpr-info.eu
(394)    The catalogue of European Strategy Forum on Research Infrastructures (ESFRI) research infrastructures portfolio can be browsed on the ESFRI website: https://ri-portfolio.esfri.eu
(395)     https://digital-strategy.ec.europa.eu/en/policies/artificial-intelligence-health
(396)     https://digital-strategy.ec.europa.eu/en/activities/digital-programme
(397)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(398)     https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(399)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(400)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(401)    In the context of this topic, multi-scale refers to modelling at different levels of human anatomy, e.g. at (sub-)cellular, tissue, organ or organ system level.
(402)    The use of the term ‘racial or ethnic origin’ does not imply an acceptance of theories that attempt to determine the existence of separate human races.
(403)    See the “European Virtual Human Twin” Coordination and Support Action EDITH, funded under the Digital Europe Programme: https://www.edith-csa.eu
(404)    Funded under the Digital Europe Programme, procedure identifier EC-CNECT/LUX/2024/OP/0014: https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/tender-details/16cc3c6a-844a-42d4-9746-dcc7444b8001-CN
(405)    For example with Regulation (EU) 2017/745 on medical devices: http://data.europa.eu/eli/reg/2017/745/oj , Regulation (EU) 2017/746 on in vitro diagnostic medical devices: http://data.europa.eu/eli/reg/2017/746/2025-01-10 , Regulation (EU) 2024/1689 laying down harmonised rules on artificial intelligence: http://data.europa.eu/eli/reg/2024/1689/oj
(406)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(407)     https://digital-strategy.ec.europa.eu/en/policies/virtual-human-twins
(408)    No contact with the developer of the Platform is required at proposal stage.
(409)    Including the projects funded under topic HORIZON-HLTH-2023-TOOL-05-03: “Integrated, multi-scale computational models of patient patho-physiology (‘virtual twins’) for personalised disease management”
(410)     https://digital-strategy.ec.europa.eu/en/activities/digital-programme
(411)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(412)     https://digital-strategy.ec.europa.eu/en/policies/cancer-imaging
(413)     https://digital-strategy.ec.europa.eu/en/policies/1-million-genomes
(414)     https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/digital-2023-cloud-ai-04-icu-data
(415)     https://cordis.europa.eu/project/id/101137129 , https://www.eppermed.eu
(416)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(417)    The guarantees shall in particular substantiate that, for the purpose of the action, measures are in place to ensure that: a) control over the applicant legal entity is not exercised in a manner that retrains or restricts its ability to carry out the action and to deliver results, that imposes restrictions concerning its infrastructure, facilities, assets, resources, intellectual property or know-how needed for the purpose of the action, or that undermines its capabilities and standards necessary to carry out the action; b) access by a non-eligible country or by a non-eligible country entity to sensitive information relating to the action is prevented; and the employees or other persons involved in the action have a national security clearance issued by an eligible country, where appropriate; c) ownership of the intellectual property arising from, and the results of, the action remain within the recipient during and after completion of the action, are not subject to control or restrictions by non-eligible countries or non-eligible country entity, and are not exported outside the eligible countries, nor is access to them from outside the eligible countries granted, without the approval of the eligible country in which the legal entity is established.
(418)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(419)     https://digital-strategy.ec.europa.eu/en/library/ai-continent-action-plan
(420)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(421)     https://research-and-innovation.ec.europa.eu/research-area/industrial-research-and-innovation/artificial-intelligence-ai-science_en
(422)     https://digital-strategy.ec.europa.eu/en/consultations/commission-launches-public-consultation-and-call-evidence-apply-ai-strategy
(423)     https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
(424)     https://digital-strategy.ec.europa.eu/en/policies/regulatory-framework-ai , https://eur-lex.europa.eu/eli/reg/2024/1689/oj
(425)     https://digital-strategy.ec.europa.eu/en/library/ethics-guidelines-trustworthy-ai
(426)     https://digital-strategy.ec.europa.eu/en/activities/digital-programme
(427)    European Research Infrastructure Consortia: https://www.eric-forum.eu/the-eric-landscap
(428)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(429)     https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/strategic-plan_en
(430)     https://commission.europa.eu/about/commission-2024-2029_en
(431)    The future of European competitiveness, Mario Draghi: https://commission.europa.eu/topics/eu-competitiveness/draghi-report_en
(432)    Much more than a market, Enrico Letta: https://www.consilium.europa.eu/media/ny3j24sm/much-more-than-a-market-report-by-enrico-letta.pdf
(433)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(434)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(435)    Entities assessed as “high-risk suppliers”, are currently set out in the second report on Member States’ progress in implementing the EU toolbox on 5G cybersecurity of 2023 (NIS Cooperation Group, Second report on Member States’ progress in implementing the EU Toolbox on 5G Cybersecurity, June 2023) and the related Communication on the implementation of the 5G cybersecurity toolbox of 2023 (Communication from the Commission: Implementation of the 5G cybersecurity Toolbox, Brussels, 15.6.2023 C(2023) 4049 final).
(436)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(437)    EMA definition: “Real-World Data are routinely collected data relating to patient health status or the delivery of healthcare from a variety of sources other than traditional clinical trials (e.g. claims databases, hospital data, electronic health records, registries, mhealth data, etc.)”.
(438)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(439)    Regulation (EU) 2017/745 of the European Parliament and of the Council of 5 April 2017 on medical devices: https://eur-lex.europa.eu/eli/reg/2017/745/oj
(440)    Regulation (EU) 2017/746 of the European Parliament and of the Council of 5 April 2017 on in vitro diagnostic medical devices: https://eur-lex.europa.eu/eli/reg/2017/746/oj
(441)    Regulation (EU) 2024/1938 of the European Parliament and of the Council of 13 June 2024 on standards of quality and safety for substances of human origin intended for human application: https://eur-lex.europa.eu/eli/reg/2024/1938/oj
(442)     https://digital-strategy.ec.europa.eu/en/policies/regulatory-framework-ai , https://eur-lex.europa.eu/eli/reg/2024/1689/oj
(443)    European Infrastructure for Translational Medicine: https://www.eatris.eu
(444)    Improved methods for clinical investigation and evaluation of high-risk medical devices: https://www.core-md.eu
(445)     https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(446)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(447)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(448)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(449)    Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application.
(450)     https://www.who.int/data/gho/data/themes/topics/sdg-target-3_3-communicable-diseases
(451)     https://www.who.int/data/gho/data/themes/topics/indicator-groups/indicator-group-details/GHO/sdg-target-3.b-development-assistance-and-vaccine-coverage
(452)     https://cordis.europa.eu/project/id/101226682 , https://beready4pandemics.eu
(453)     https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1306
(454)    Good Manufacturing Practices: https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(455)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(456)    Gouglas, D. et al.: Estimating the cost of vaccine development against epidemic infectious diseases: a cost minimisation study. Lancet Global Health Vol. 6 (12) E1386-E1396. DOI: https://doi.org/10.1016/S2214-109X(18)30346-2 , https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(18)30346-2/fulltext
(457)    One Health governance in the European Union - Scientific Advice Mechanism: https://scientificadvice.eu/advice/one-health-governance-in-the-european-union
(458)     https://cordis.europa.eu/project/id/101217154 , https://ohamr.eu
(459)     https://cordis.europa.eu/project/id/101136346 , https://www.eupahw.eu
(460)     https://cordis.europa.eu/project/id/101226682 , https://beready4pandemics.eu
(461)    European Climate and Health Observatory: https://climate-adapt.eea.europa.eu/en/observatory
(462)    EU Global Health Strategy: Better Health for All in a Changing World - European Commission: https://health.ec.europa.eu/publications/eu-global-health-strategy-better-health-all-changing-world_en
(463)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(464)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(465)    Commission Communication on Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU; COM(2024) 137 final: https://research-and-innovation.ec.europa.eu/document/download/47554adc-dffc-411b-8cd6-b52417514cb3_en
(466)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en ; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686
(467)     https://ec.europa.eu/info/law/better-regulation/have-your-say/initiatives/14627-Biotech-Act_en
(468)     https://commission.europa.eu/document/download/98c6e4dc-0fc3-4ec6-8ec2-bfcdcb2f018a_en?filename=policy_com-2024-206_en.pdf
(469)     https://www.ema.europa.eu/en/about-us/how-we-work/european-medicines-regulatory-network
(470)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(471)     https://www.who.int/data/gho/data/themes/topics/sdg-target-3_3-communicable-diseases
(472)     https://www.who.int/data/gho/data/themes/topics/indicator-groups/indicator-group-details/GHO/sdg-target-3.b-development-assistance-and-vaccine-coverage
(473)     https://cordis.europa.eu/project/id/101226682 , https://beready4pandemics.eu
(474)     https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1306
(475)    Good Manufacturing Practices: https://health.ec.europa.eu/medicinal-products/eudralex/eudralex-volume-4_en
(476)     https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32003H0361
(477)    Gouglas, D. et al.: Estimating the cost of vaccine development against epidemic infectious diseases: a cost minimisation study. Lancet Global Health Vol. 6 (12) E1386-E1396. DOI: https://doi.org/10.1016/S2214-109X(18)30346-2 , https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(18)30346-2/fulltext
(478)     https://commission.europa.eu/strategy-and-policy/priorities-2019-2024/european-green-deal_en
(479)     https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en
(480)     https://op.europa.eu/en/publication-detail/-/publication/616cce9c-39e5-11f0-8a44-01aa75ed71a1
(481)     https://commission.europa.eu/funding-tenders/find-funding/eu-funding-programmes/eu4health_en
(482)     https://commission.europa.eu/strategy-and-policy/priorities-2019-2024/promoting-our-european-way-life/european-health-union_en
(483)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(484)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(485)    Should there be no Public Health Emergency in 2026 or 2027, the indicative budget may be reallocated.
(486)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A32022R2371&qid=1673372768554
(487)    Article 198 (b) of the Financial Regulation 2018/1046 "Grants may be awarded without a call for proposals only in the following cases: [...] (b) in other exceptional and duly substantiated emergencies;”.
(488)    See definition of FAIR data in the introduction to this Work Programme part.
(489)    The Commission is a member of the HFSP Organization (HFSPO) and has funded HFSP under previous Framework Programmes
(490)    Communication from the Commission on the Global Approach to Research and Innovation. Europe’s strategy for international cooperation in a changing world, COM(2021) 252, 18.5.2021 ( https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=COM%3A2021%3A252%3AFIN ).
(491) The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The budget figures given in this table are rounded to two decimal places.
(492) The contribution from Cluster 1 for year 2027 is EUR 122.60 million for the Missions work programme part and EUR 22.23 million for the New European Bauhaus Facility work programme part.    The contribution from Cluster 1 for year 2026 is EUR 124.70 million for the Missions work programme part and EUR 23.31 million for the New European Bauhaus Facility work programme part.
(493)    To which EUR 10.00 million from the 'Climate, Energy and Mobility' budget will be added making a total of EUR 341.60 million for this call.
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EN

Annex V

Horizon Europe

Work Programme 2026-2027

5. Culture, Creativity and Inclusive Society

Table of contents

Introduction    

CALLS 2026    

Call - Culture, Creativity and Inclusive Society 2026    

Overview of this call    

Call - Cluster 2 Partnerships    

Overview of this call    

CALLS 2027    

Call - Culture, Creativity and Inclusive Society - 2027    

Overview of this call    

Call - Culture, Creativity and Inclusive Society - 2027 - Two-stage    

Overview of this call    

DESTINATIONS    

Destination Innovative Research on Democracy and Governance    

HORIZON-CL2-2026-01-DEMOCRACY-01: Tackling gender-based violence against politically active women and LGBTIQ people    

HORIZON-CL2-2026-01-DEMOCRACY-02: Understanding the forms of local democracy in low-income and low-middle income countries    

HORIZON-CL2-2026-01-DEMOCRACY-03: Government in transition – how governments change the way they work and prepare the civil service for the future    

HORIZON-CL2-2026-01-DEMOCRACY-04: Sustainable paths to media viability    

HORIZON-CL2-2026-01-DEMOCRACY-05: Research and Innovation Network for a Union of Equality    

HORIZON-CL2-2026-01-DEMOCRACY-06: Governing global commons sustainably    

HORIZON-CL2-2026-01-DEMOCRACY-07: Supporting post-conflict democracy and reconstruction    

HORIZON-CL2-2026-01-DEMOCRACY-08: Electoral integrity in the digital context    

HORIZON-CL2-2026-01-DEMOCRACY-09: Citizenship education as part of lifelong learning    

HORIZON-CL2-2026-01-DEMOCRACY-10: Digital and media literacy as drivers for democratic and civic resilience    

HORIZON-CL2-2027-01-DEMOCRACY-01: Advisory support and network for countering and preventing radicalisation, extremism, hate speech and polarisation    

HORIZON-CL2-2027-01-DEMOCRACY-02: Women’s, LGBTIQ and minority rights in a context of autocracy, conflict and geopolitical shifts    

HORIZON-CL2-2027-01-DEMOCRACY-03: Student and family engagement for developing a culture of democratic/civic participation    

HORIZON-CL2-2027-01-DEMOCRACY-04: Addressing the impact of artificial intelligence, cyberviolence, and deepfakes on equality, democracy and inclusive societies    

HORIZON-CL2-2027-01-DEMOCRACY-05: Development aid and democratic governance    

HORIZON-CL2-2027-01-DEMOCRACY-06: Identifying user-focused solutions to support news media freedom    

HORIZON-CL2-2027-01-DEMOCRACY-07: The role of private companies in democracy    

HORIZON-CL2-2027-01-DEMOCRACY-08: Global Human Rights and EU values    

HORIZON-CL2-2027-02-DEMOCRACY-09-two-stage: Open topic on reinvigorating and shielding European democracy    

Destination Innovative Research on European Cultural Heritage and Cultural and Creative Industries    

EUROPE’S SUSTAINABLE PROSPERITY AND COMPETITIVENESS    

HORIZON-CL2-2026-01-HERITAGE-01: “Artistic intelligence” : harnessing the power of the arts to address complex challenges, enhance soft skills and boost innovation and competitiveness    

HORIZON-CL2-2026-01-HERITAGE-02: Boosting creative startups for disruptive innovation    

HORIZON-CL2-2026-01-HERITAGE-03: AI integration in CCSI work practice: catalysing innovation and competitiveness    

HORIZON-CL2-2026-01-HERITAGE-04: Towards a fair and transparent market for cultural and creative content in the era of generative AI    

HORIZON-CL2-2026-01-HERITAGE-05: Creative alliances: Fostering global partnerships in cultural policies and CCI innovation    

SUPPORTING PEOPLE, STRENGTHENING OUR SOCIETIES AND OUR SOCIAL MODEL    

HORIZON-CL2-2026-01-HERITAGE-06: Safeguarding linguistic diversity in Europe    

HORIZON-CL2-2026-01-HERITAGE-07: Preventing and fighting illicit trafficking of cultural goods    

EUROPE’S SUSTAINABLE PROSPERITY AND COMPETITIVENESS    

HORIZON-CL2-2027-01-HERITAGE-01: Towards a consolidated culture and creativity driven European innovation ecosystem    

HORIZON-CL2-2027-01-HERITAGE-02: AI4Creatives Support Platform: embracing a fair AI revolution    

HORIZON-CL2-2027-01-HERITAGE-03: Crafting routes to a circular economy    

SUPPORTING PEOPLE, STRENGTHENING OUR SOCIETIES AND OUR SOCIAL MODEL    

HORIZON-CL2-2027-01-HERITAGE-04: Culture, heritage and creative industries for health and well-being    

HORIZON-CL2-2027-01-HERITAGE-05: Re-imagining the creative economy: the interplay between the cultural and creative sectors and industries and the social economy    

HORIZON-CL2-2027-01-HERITAGE-06: Future-proofing sustainable cultural tourism    

HORIZON-CL2-2027-01-HERITAGE-07: Societal impact of cultural heritage    

HORIZON-CL2-2027-01-HERITAGE-08: Safeguarding & transmission of intangible cultural heritage    

HORIZON-CL2-2027-02-HERITAGE-09-two-stage: Open topic: Impact-driven research on realising the full potential of cultural heritage, arts and cultural and creative industries    

Destination Innovative Research on Social and Economic Transformations    

HORIZON-CL2-2026-02-TRANSFO-01: Co-funded European Partnership for Social Transformations and Resilience    

HORIZON-CL2-2026-01-TRANSFO-02: Open topic: Strengthen Europe's social model and sustainable competitiveness through productivity    

HORIZON-CL2-2026-01-TRANSFO-03: Tackling child poverty and ensuring disadvantaged children's access to Early Childhood Education and Care    

HORIZON-CL2-2026-01-TRANSFO-04: The impact of the use of digital tools outside school and for communication on educational outcomes and mental health    

HORIZON-CL2-2026-01-TRANSFO-05: Contribution of basic skills to productivity, innovation, competitiveness and economic growth    

HORIZON-CL2-2026-01-TRANSFO-06: Making Europe a global magnet for talent - Attracting and retaining students, researchers and high-skilled workers from outside the EU    

HORIZON-CL2-2026-01-TRANSFO-07: Fostering competences for the green transition    

HORIZON-CL2-2026-01-TRANSFO-08: Strengthened implementation of the EU Pact on Migration and Asylum and a focus on inclusion, integration, and health    

HORIZON-CL2-2026-01-TRANSFO-09: Rethinking long-term care policy in the face of EU demographic shifts    

HORIZON-CL2-2026-01-TRANSFO-10: Fostering cooperation and integration between SSH and STEM research and innovation in the EU    

HORIZON-CL2-2027-01-TRANSFO-01: Impact of access to nature-positive environments in promoting social cohesion and reducing inequalities in urban and peri-urban settings    

HORIZON-CL2-2027-01-TRANSFO-02: Impact of in-kind benefits on income distribution and on vulnerable populations    

HORIZON-CL2-2027-01-TRANSFO-03: Rethinking sustainable competitiveness beyond traditional perspectives: role and contribution of the Social Economy    

HORIZON-CL2-2027-01-TRANSFO-04: The impact of EU labour mobility on the Member States of the EU    

HORIZON-CL2-2027-01-TRANSFO-05: The effective use of artificial intelligence in learning environments in pre-primary and primary education    

HORIZON-CL2-2027-01-TRANSFO-06: Closing the learning gap: uncovering causes and effective policy interventions for declining youth skills in mathematics, reading, and science    

HORIZON-CL2-2027-01-TRANSFO-07: Persons with disabilities: opportunities for labour inclusion and social protection through the life course    

HORIZON-CL2-2027-01-TRANSFO-08: Scaling and deploying innovations in migration management    

HORIZON-CL2-2027-02-TRANSFO-09-two-stage: Improving socio-economic outcomes for persons with dementia and informal caregivers    

OTHER ACTIONS not subject to calls for proposals    

Grants to identified beneficiaries    

1. Presidency event (Lithuania): Re-thinking EU's competitiveness: How do cultural and creative industries contribute?    

2. Presidency event (Greece): Cultural Heritage for Sustainable Futures    

Public procurements    

1. Studies, conferences, events and outreach activities    

2. Studies, conferences, events and outreach activities    

Other budget implementation instruments    

1. Expertise for the design, implementation and evaluation of Cluster 2, Culture, Creativity and Inclusive Society    

2. External expertise - Monitors    

3. Expertise for the design, implementation and evaluation of Cluster 2, Culture, Creativity and Inclusive Society    

4. External expertise - Monitors    

Budget    

Introduction

Cluster 2, ‘Culture, Creativity and Inclusive Society’ aims to meet EU goals and priorities on enhancing democratic governance and citizens participation, on the safeguarding and promotion of cultural heritage, and to respond to and shape multifaceted social, economic, technological and cultural transformations. Cluster 2 mobilises multidisciplinary expertise of European social sciences and humanities (SSH) for understanding fundamental contemporary transformations of society, economy, politics and culture. It aims to provide evidence-based policy options for a socially just and inclusive European green and digital transition and recovery.

The EU is strongly committed to the UN Sustainable Development Goals (SDGs), many of which have an important impact on culture, creativity, and inclusive society, notably: SDG 1 (No poverty), SDG 3 (Good Health and Well-being), SDG 4 (Quality Education), SDG 5 (Gender Equality), SDG 8 (Decent Work and Economic Growth), SDG 10 (Reduced Inequalities), SDG 11 (Sustainable Cities and Communities), SDG 12 (Responsible Consumption and Production), and SDG 16 (Peace, Justice, and Strong Institutions), with their specific targets to achieve a better and more sustainable future for all.

Proposals are invited against the following three (3) destinations:

Activities contributing to the destination "Innovative Research on Democracy and Governance", will provide knowledge, data and scientifically robust recommendations to reinvigorate and strengthen democratic governance, improve critical thinking and trust in democratic institutions. In the long-term, this will contribute to help safeguard fundamental rights to empower active and inclusive citizenship. Research will contribute to understanding current challenges and threats and mapping future pathways for innovative solutions to issues such as addressing the impact of AI and the digital transformation of democracy, reinforcing democratic resilience and civic preparedness and preserving the role of free and plural media as key tenets of democracy. Projects will develop a robust evidence base on which to build effective, relevant and sensible policies that bolster the resilience of democratic systems and protect them from threats, while contributing at the same time to rebuilding citizens’ trust in democracy, its institutions, and the sense of political participation in its widest possible sense.

Activities contributing to the destination "Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries", will support research and innovation to boost sustainable growth and job creation through the cultural and creative industries. They will contribute to Europe’s sustainable prosperity and competitiveness by boosting the innovation-driving role of the Cultural and Creative Industries (CCIs), and by focusing in areas such as creative startups, the impact of artificial intelligence technologies on creativity and CCIs and promoting a circular economy and global partnerships in cultural policies and CCIs. They will help supporting people and strengthen our societies and our social model by boosting the role of culture, the arts and creative industries for well-being, the social economy and society. R&I actions will explore and strengthen the role of culture, heritage and CCIs in shaping the technologies of the future and focus on safeguarding intangible heritage and linguistic diversity, on sustainable cultural tourism and on countering illicit trafficking of cultural goods, among others.

At the same time, through the destination "Innovative Research on Social and Economic Transformations", actions will help tackle social, economic and political inequalities, support human capital development and contribute to a comprehensive European strategy for inclusive growth. Activities will improve the understanding of how technological, climate, economic and demographic changes impact society. They will inform the design of policies addressing existing and emerging challenges, harnessing new opportunities (particularly in the areas of employment, education, mental health and well-being) and contributing to reaching the objectives set out by the Action Plan of the European Pillar of Social Rights. A key focus of the activities will be to boost sustainability and inclusion, by supporting vulnerable groups and protecting individuals from discrimination (based on sex, gender, racial or ethnic origin, religion or belief, disability, age or sexual orientation).

A new European Partnership on Social Transformations and Resilience 1 , focused on the Social Sciences and Humanities (SSH), will be launched under the Cluster 2 work programme part. The partnership will fund research and innovation activities in the areas of the future of work, modernisation of social protection and essential services, education and skills development and a fair transition towards climate neutrality.

Horizon Europe is the research and innovation programme in a system of European and national funding programmes which share policy objectives. Through the programme, special attention will be given to ensuring cooperation between universities, scientific communities and industry, including small and medium enterprises, and citizens and their representatives, to bridge gaps between territories, generations and regional cultures, especially caring for the needs of the young in shaping Europe’s future. Funded projects could be EU Synergies grants, meaning that as such, they have the possibility to also receive funding under other EU programmes. To enable synergies by design in this context, project proposers should consider and actively seek strategic combinations with, and where appropriate possibilities for further funding from, other R&I-relevant EU, national or regional and cross-border programmes (such as ERDF including Interreg, ESF+, JTF, EMFF, EAFRD and InvestEU), as well as private funds or financial instruments.

The EU’s Recovery and Resilience Facility (RRF) aims at financing projects that directly tackle the economic and social impacts from the Coronavirus crisis and support the green and digital transition. For project ideas that directly contribute to these objectives and that have a strong focus in one Member State it is advisable to check access to the RRF for a fast and targeted support.

Synergies with relevant Union programmes will be sought, regarding the take-up of research results and innovative solutions developed under Horizon Europe, for example via the following programmes:

1.Creative Europe: it improves the safeguarding and valorisation of cultural heritage and further supports the cultural and creative sector. Creative Europe can improve sectorial networking and cooperation of Member States and non-EU Participating Countries in the Creative Europe Programme 2 to apply the latest technologies, stimulate new scientific approaches and boost innovation potential stemming from Horizon Europe.

2.Erasmus+: it supports efforts to efficiently use the potential of Europe’s talent and social assets in a lifelong learning perspective throughout the education, training and youth fields. It promotes measures for the inclusion of people with fewer opportunities, including newly arrived migrants, and supports skills development and citizens’ participation and engagement, encouraging young people to engage and learn to participate in civic society and democratic life, raising awareness about EU values, including via online platforms and tools for virtual cooperation. As regards Cluster 2, Erasmus+ projects could benefit for instance from the use of innovative practices for migrant integration in education, up-take of innovative methods for citizen engagement and education for fostering EU values and democracy stemming from Horizon Europe.

3.Global Europe, the EU’s Neighbourhood, Development and International Cooperation Instrument: it supports and consolidates democracy, rule of law and human rights, supports civil society organisations outside the EU, furthers stability and peace and addresses other global challenges including migration and mobility. The actions can benefit from drawing on the findings of H2020 and Horizon Europe projects regarding trust in governance, countering disinformation and citizens’ participation and engagement.

4.Digital Europe Programme (DIGITAL): while Horizon Europe supports research and development of digital technologies, DIGITAL supports the wide uptake and deployment of innovative digital solutions in areas of public interest (including public administration, justice and education), by setting up and making accessible Europe-wide data spaces and platforms and providing SMEs and public administrations access to the latest digital technologies, for example via Digital Innovation Hubs. Priority actions for the first four years of DIGITAL include “Safer internet for kids”, a “Platform for combating disinformation”, supporting the EU language technology industry in developing and deploying latest AI-based technologies in all EU languages, contributing to the skills and employment of ICT professionals (including women and girls) and the EU digital platform for cultural heritage, Europeana, which supports the digital transformation of cultural heritage institutions.

5.Technical Support Instrument (TSI): by supporting the efforts of the national authorities in improving their administrative capacity to design, develop and implement reforms, the TSI can benefit from the good practices, innovative processes and methodologies identified or developed in H2020 and Horizon Europe projects, and get access to the expertise in research bodies participating to such projects.

6.Citizens, Equality, Rights and Values programme (CERV): the programme can draw on the results of H2020 and Horizon Europe projects in the field of citizens’ engagement, to support civil society organisations in encouraging and facilitating active participation in the construction of a more democratic Union and awareness raising of EU rights and values.

7.European Social Fund Plus (ESF+): The programme aims to promote social cohesion and equip people with the skills needed for the evolving demands of the labour market. Member States and regions can use the ESF+ to mainstream and upscale innovative technologies and solutions in the areas of employment, social inclusion, education and training, including successful models and practices developed under Horizon 2020 and Horizon Europe. In addition, the ESF+ can support operations and researchers granted a Seal of Excellence under Horizon Europe.

8.European Regional Development Fund: ERDF focuses, among others, on the development and strengthening of regional and local research and innovation ecosystems and smart economic transformation, in line with regional/national smart specialisation strategies. It can support investment in research infrastructures, activities for applied research and innovation (including industrial research), experimental development and feasibility studies, building research and innovation capacities and the uptake of advanced technologies and roll-out of innovative solutions from the Framework Programmes for research and innovation through the ERDF. It helps governments reap the benefits of digitisation and encourages investments in social and cultural infrastructure, the development of cultural services and the conservation of cultural heritage. Interreg is a main instrument of ERDF to support cooperation across regions and countries. Support to the protection and development of cultural heritage, to SMEs, to social innovation in culture and creative industries is central to Interreg. Interreg can also complement Horizon Europe’s initiatives by supporting policy learning and regional cooperation.

9.European Agricultural Fund for Rural Development (EAFRD): relevant stakeholders can benefit from the dissemination and take-up of R&I results in the field of cultural heritage, in particular in rural and remote areas.

10.The InvestEU Programme can fund the uptake of R&I results related to Cultural and Creative Industries (CCI) and cultural heritage.

11.The Asylum, Migration and Integration Fund (AMIF) supports the EU migration policy to strengthen and develop all aspects of the common European asylum system, support legal migration to the Member States and effective integration policies. It contributes to countering irregular migration. Horizon Europe contributes to the implementation of the AMIF providing an evidence base for policies and projects, as regards asylum protection, legal and irregular migration management and migrant integration.

To increase the impact of EU investments under Horizon Europe, the European Commission encourages collaboration between EU-funded projects to build on complementarities through networking, joint workshops, knowledge exchange, best practices, and joint communication activities. Complementarities can be explored between projects funded under the same or different topics, Clusters or pillars of Horizon Europe. This includes collaborations between projects funded under Cluster 1 and Cluster 2 for complementary actions, such as promoting social inclusion, health equity (including gender equality and support for marginalised groups), and mental health initiatives in education, work, and daily life (including through culture and the arts). The cross-cluster complementarities are set out in detail in the Strategic Plan of Horizon Europe for 2025-2027.

In line with the EU’s Global Approach to Research and Innovation, and similarly to the previous Work Programmes, the Work Programme 2026-27 will remain almost completely open to the participation of non-associated third countries to all Research and Innovation Action (RIA) and Innovation Action (IA) topics. In support of the Global Gateway Strategy 3 , projects involving international partners should lead to increased scientific knowledge and transfer of technology among partner countries allowing to address global challenges across the world and create sustainable growth and jobs. Cooperation should take place in a value-based way, creating linkages, not dependencies.

Applicants are encouraged to consider, where appropriate, interweaving in the methodology of their proposals open science practices beyond the mandatory requirements of Horizon Europe, such as early and open sharing of research (e.g. through preprints), measures to ensure reproducibility of research outputs, open access to research outputs other than publications or data, participation in open peer-review.

Applicants are encouraged to consider, where relevant, the services offered by the current and future EU-funded European Research Infrastructures, particularly those in the social sciences and humanities domain 4 .

Eligibility to participate is subject to the ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility condition (see General Annex B of the General Annexes). Furthermore, legal entities established in China are not eligible to participate in Innovation Actions in any capacity. Please refer to the Annex B of the General Annexes of this Work Programme for further details.

The topics in this cluster require the effective and extensive contribution of SSH disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, to produce meaningful and significant effects enhancing the societal impact of the related research activities.

CALLS 2026

Call - Culture, Creativity and Inclusive Society 2026

HORIZON-CL2-2026-01

Overview of this call 5

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 6

Indicative number of projects expected to be funded

2026

Opening: 12 May 2026

Deadline(s): 23 Sep 2026

Destination Innovative Research on Democracy and Governance

HORIZON-CL2-2026-01-DEMOCRACY-01: Tackling gender-based violence against politically active women and LGBTIQ people

RIA

12.00

3.50 to 4.00

3

HORIZON-CL2-2026-01-DEMOCRACY-02: Understanding the forms of local democracy in low-income and low-middle income countries

RIA

12.00

3.50 to 4.00

3

HORIZON-CL2-2026-01-DEMOCRACY-03: Government in transition – how governments change the way they work and prepare the civil service for the future

RIA

8.00

3.50 to 4.00

2

HORIZON-CL2-2026-01-DEMOCRACY-04: Sustainable paths to media viability

IA

12.00

3.50 to 4.00

3

HORIZON-CL2-2026-01-DEMOCRACY-05: Research and Innovation Network for a Union of Equality

CSA

4.50

4.00 to 4.50

1

HORIZON-CL2-2026-01-DEMOCRACY-06: Governing global commons sustainably

RIA

12.00

3.50 to 4.00

3

HORIZON-CL2-2026-01-DEMOCRACY-07: Supporting post-conflict democracy and reconstruction

RIA

12.00

3.50 to 4.00

3

HORIZON-CL2-2026-01-DEMOCRACY-08: Electoral integrity in the digital context

RIA

12.00

3.50 to 4.00

3

HORIZON-CL2-2026-01-DEMOCRACY-09: Citizenship education as part of lifelong learning

RIA

16.00

3.50 to 4.00

4

HORIZON-CL2-2026-01-DEMOCRACY-10: Digital and media literacy as drivers for democratic and civic resilience

RIA

12.00

3.50 to 4.00

3

Destination Innovative Research on European Cultural Heritage and Cultural and Creative Industries

HORIZON-CL2-2026-01-HERITAGE-01: “Artistic intelligence” : harnessing the power of the arts to address complex challenges, enhance soft skills and boost innovation and competitiveness

RIA

15.00

4.50 to 5.00

3

HORIZON-CL2-2026-01-HERITAGE-02: Boosting creative startups for disruptive innovation

IA

12.00

5.00 to 6.00

2

HORIZON-CL2-2026-01-HERITAGE-03: AI integration in CCSI work practice: catalysing innovation and competitiveness

IA

15.00

4.00 to 5.00

3

HORIZON-CL2-2026-01-HERITAGE-04: Towards a fair and transparent market for cultural and creative content in the era of generative AI

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2026-01-HERITAGE-05: Creative alliances: Fostering global partnerships in cultural policies and CCI innovation

RIA

15.00

3.00 to 3.75

4

HORIZON-CL2-2026-01-HERITAGE-06: Safeguarding linguistic diversity in Europe

RIA

11.50

5.00 to 5.75

2

HORIZON-CL2-2026-01-HERITAGE-07: Preventing and fighting illicit trafficking of cultural goods

CSA

5.00

4.50 to 5.00

1

Destination Innovative Research on Social and Economic Transformations

HORIZON-CL2-2026-01-TRANSFO-02: Open topic: Strengthen Europe's social model and sustainable competitiveness through productivity

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2026-01-TRANSFO-03: Tackling child poverty and ensuring disadvantaged children's access to Early Childhood Education and Care

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2026-01-TRANSFO-04: The impact of the use of digital tools outside school and for communication on educational outcomes and mental health

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2026-01-TRANSFO-05: Contribution of basic skills to productivity, innovation, competitiveness and economic growth

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2026-01-TRANSFO-06: Making Europe a global magnet for talent - Attracting and retaining students, researchers and high-skilled workers from outside the EU

RIA

10.00

3.00 to 3.30

3

HORIZON-CL2-2026-01-TRANSFO-07: Fostering competences for the green transition

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2026-01-TRANSFO-08: Strengthened implementation of the EU Pact on Migration and Asylum and a focus on inclusion, integration, and health

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2026-01-TRANSFO-09: Rethinking long-term care policy in the face of EU demographic shifts

RIA

15.00

Around 3.75

4

HORIZON-CL2-2026-01-TRANSFO-10: Fostering cooperation and integration between SSH and STEM research and innovation in the EU

CSA

3.50

Around 3.50

1

Overall indicative budget

298.50

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Cluster 2 Partnerships

HORIZON-CL2-2026-02

Overview of this call 7

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 8

Indicative number of projects expected to be funded

2026

Opening: 12 May 2026

Deadline(s): 13 Oct 2026

Destination Innovative Research on Social and Economic Transformations

HORIZON-CL2-2026-02-TRANSFO-01: Co-funded European Partnership for Social Transformations and Resilience

COFUND

60.00

Around 60.00

1

Overall indicative budget

60.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

CALLS 2027

Call - Culture, Creativity and Inclusive Society - 2027

HORIZON-CL2-2027-01

Overview of this call 9

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 10

Indicative number of projects expected to be funded

2027

Opening: 13 May 2027

Deadline(s): 23 Sep 2027

Destination Innovative Research on Democracy and Governance

HORIZON-CL2-2027-01-DEMOCRACY-01: Advisory support and network for countering and preventing radicalisation, extremism, hate speech and polarisation

CSA

3.50

3.00 to 3.50

1

HORIZON-CL2-2027-01-DEMOCRACY-02: Women’s, LGBTIQ and minority rights in a context of autocracy, conflict and geopolitical shifts

RIA

12.00

3.50 to 4.00

3

HORIZON-CL2-2027-01-DEMOCRACY-03: Student and family engagement for developing a culture of democratic/civic participation

RIA

12.00

3.50 to 4.00

3

HORIZON-CL2-2027-01-DEMOCRACY-04: Addressing the impact of artificial intelligence, cyberviolence, and deepfakes on equality, democracy and inclusive societies

RIA

20.00

3.50 to 4.00

5

HORIZON-CL2-2027-01-DEMOCRACY-05: Development aid and democratic governance

RIA

12.00

3.50 to 4.00

3

HORIZON-CL2-2027-01-DEMOCRACY-06: Identifying user-focused solutions to support news media freedom

RIA

12.00

3.50 to 4.00

3

HORIZON-CL2-2027-01-DEMOCRACY-07: The role of private companies in democracy

RIA

8.00

3.50 to 4.00

2

HORIZON-CL2-2027-01-DEMOCRACY-08: Global Human Rights and EU values

RIA

12.00

3.50 to 4.00

3

Destination Innovative Research on European Cultural Heritage and Cultural and Creative Industries

HORIZON-CL2-2027-01-HERITAGE-01: Towards a consolidated culture and creativity driven European innovation ecosystem

CSA

5.00

4.50 to 5.00

1

HORIZON-CL2-2027-01-HERITAGE-02: AI4Creatives Support Platform: embracing a fair AI revolution

CSA

5.00

4.50 to 5.00

1

HORIZON-CL2-2027-01-HERITAGE-03: Crafting routes to a circular economy

RIA

10.50

3.00 to 3.50

3

HORIZON-CL2-2027-01-HERITAGE-04: Culture, heritage and creative industries for health and well-being

RIA

16.00

3.00 to 4.00

4

HORIZON-CL2-2027-01-HERITAGE-05: Re-imagining the creative economy: the interplay between the cultural and creative sectors and industries and the social economy

RIA

10.50

3.00 to 3.50

3

HORIZON-CL2-2027-01-HERITAGE-06: Future-proofing sustainable cultural tourism

RIA

14.50

4.00 to 4.80

3

HORIZON-CL2-2027-01-HERITAGE-07: Societal impact of cultural heritage

RIA

15.00

2.50 to 3.00

5

HORIZON-CL2-2027-01-HERITAGE-08: Safeguarding & transmission of intangible cultural heritage

RIA

12.00

3.00 to 4.00

3

Destination Innovative Research on Social and Economic Transformations

HORIZON-CL2-2027-01-TRANSFO-01: Impact of access to nature-positive environments in promoting social cohesion and reducing inequalities in urban and peri-urban settings

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2027-01-TRANSFO-02: Impact of in-kind benefits on income distribution and on vulnerable populations

RIA

10.00

3.00 to 3.30

3

HORIZON-CL2-2027-01-TRANSFO-03: Rethinking sustainable competitiveness beyond traditional perspectives: role and contribution of the Social Economy

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2027-01-TRANSFO-04: The impact of EU labour mobility on the Member States of the EU

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2027-01-TRANSFO-05: The effective use of artificial intelligence in learning environments in pre-primary and primary education

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2027-01-TRANSFO-06: Closing the learning gap: uncovering causes and effective policy interventions for declining youth skills in mathematics, reading, and science

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2027-01-TRANSFO-07: Persons with disabilities: opportunities for labour inclusion and social protection through the life course

RIA

12.00

3.00 to 4.00

3

HORIZON-CL2-2027-01-TRANSFO-08: Scaling and deploying innovations in migration management

IA

15.00

3.00 to 3.75

4

Overall indicative budget

277.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Culture, Creativity and Inclusive Society - 2027 - Two-stage

HORIZON-CL2-2027-02-TWO-STAGE

Overview of this call 11

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 12

Indicative number of projects expected to be funded

2027

Opening: 02 Mar 2027

Deadline(s): 04 May 2027 (First Stage), 30 Sep 2027 (Second Stage)

Destination Innovative Research on Democracy and Governance

HORIZON-CL2-2027-02-DEMOCRACY-09-two-stage: Open topic on reinvigorating and shielding European democracy

RIA

22.00

2.00 to 3.70

6

Destination Innovative Research on European Cultural Heritage and Cultural and Creative Industries

HORIZON-CL2-2027-02-HERITAGE-09-two-stage: Open topic: Impact-driven research on realising the full potential of cultural heritage, arts and cultural and creative industries

RIA

20.00

2.00 to 4.00

5

Destination Innovative Research on Social and Economic Transformations

HORIZON-CL2-2027-02-TRANSFO-09-two-stage: Improving socio-economic outcomes for persons with dementia and informal caregivers

RIA

16.00

Around 3.20

5

Overall indicative budget

58.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

DESTINATIONS

Destination Innovative Research on Democracy and Governance

The rule of law, respect for human rights and democracy are foundational values of the EU laid down in Article 2 of the Treaty on European Union. These values provide the Union with principled orientations to meet the inevitable geopolitical economic, social and demographic changes that could not be foreseen at the time the Treaties were drafted. This includes how the digital transformation would affect how the debate and political processes would be shaped.

Democracy is cultural practice as much as it is a political system. It is a key strength of European societies, helping ensure respect for equality, the rule of law, fundamental rights and liberty. Actors with anti-democratic tendencies attack democracies and their institutions because democracy is a safeguard against them 13 . Even traditionally well-functioning democracies face many challenges, which means that they also continuously need to adapt as conditions change. Social sciences and humanities (SSH) research plays a crucial role in understanding current challenges and threats and mapping future pathways for innovative solutions. Building on historical, cultural, social, legal and philosophical perspectives, research will foster the further development of democracy with a view to enhancing citizen participation and inclusive policymaking, promoting equality and inclusiveness, addressing the impact of AI and the digital transformation of democracy. It will also reinforce democratic resilience and civic preparedness, and preserve the role of free, independent and plural media as key tenets of democracy, among other objectives.

Expected impact:

Proposals for topics under this destination should set out a credible pathway to contributing to the following expected impact of the Horizon Europe Strategic Plan:

1.Reinvigorating democratic governance by improving the independence, accountability, transparency, effectiveness and trustworthiness of institutions and policies based on rule of law, and through the expansion of active and inclusive citizens’ participation and engagement empowered by the safeguarding of fundamental rights.

The aim of the research investment supporting this impact is to develop a robust evidence base that can inform the establishment of effective, relevant and sensible policies, which bolster the resilience of democratic systems and protect them from threats. At the same time, it seeks to foster critical thinking while also reinforcing citizens’ trust in democracy, its institutions, and the sense of political participation in its widest possible sense.

The destination seeks synergies with other relevant EU programmes, in particular for the uptake of research results and innovative solutions developed under Horizon Europe. Interaction – among others – with the following programmes is encouraged: Digital Europe (DIGITAL), Technical Support Instrument, CERV (Citizens, Equality, Rights and Values), Erasmus+, ESF+ and Global Europe: Neighbourhood, Development and International Cooperation Instrument.

Applicants are encouraged to consider, where relevant, the services offered by the current and future EU-funded European Research Infrastructures, particularly those in the social sciences and humanities domain 14 . Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud, as well as data from relevant Data Spaces.

As the destination aims directly at citizen engagement and at producing lasting change, it is of particular importance that the research and innovation actions promote the highest standards of transparency and openness. Particular efforts should be made to ensure that the data produced in the context of this destination is FAIR (Findable, Accessible, Interoperable and Re-usable). When applicable, it is encouraged to open up the process, criteria, methodologies and data to civil society in the course of the research.

To maximise the impacts of R&I under this Destination in line with EU priorities, international cooperation is encouraged whenever relevant in the proposed topics.

Proposals are invited against the following topic(s):

HORIZON-CL2-2026-01-DEMOCRACY-01: Tackling gender-based violence against politically active women and LGBTIQ people

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 15 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.EU and national policymakers and relevant stakeholders get an enhanced understanding of the drivers of violence against women and LGBTIQ people who are politically active or political aspirants.

2.Enhanced prevention and early intervention through better understanding of the drivers and impacts of violence (short- and long-term) on women and LGBTIQ people engaged, or aspiring to engage, in online and offline political activities and how their participation evolves after experiencing violence and harassment.

3.Uptake of evidence-based policy recommendations by policymakers and relevant stakeholders on tackling gender-based violence alongside violence against politically active women and LGBTIQ people, promoting equal political participation and addressing harmful narratives.

4.Broader adherence to media guidelines on responsible, ethical, and safe portrayals of and reporting on gender-based violence in a political context, embedding gender-sensitive and intersectional reporting and incorporating successful practices with demonstrable, positive outcomes.

5.Promotion of an inclusive environment that encourages political participation of women, and LGBTIQ people, notably from underrepresented groups, through collaboration across key public, political and civil society actors.

Scope: The increased participation and visibility of women and LGBTIQ people in public life 16 coincides with a rise in two severe forms of violence: politically motivated violence targeting public figures and gender-based violence (GBV). 17 When these two forms of violence intersect, they obstruct progress toward equality, reinforce traditional gender norms and stereotypes, power imbalances, and pose significant threats to democratic societies.

The EU Directive on combating violence against women acknowledges the impact of violence on women active in public life, particularly its silencing effect. The European Commission’s 2024-2029 political guidelines place the fight against GBV at the heart of the post-2025 Equality Strategy, notably to empower women in politics 18 . The Roadmap for Women’s Rights 19 recalls that women “face higher risks of threats and violence limiting their participation in public life”, while the Equality Commissioner’s Mission Letter identifies hate-motivated harassment and (online) violence as a key focus for the EU LGBTIQ equality strategy for 2026-2030. The mission letter to the Commissioner for Democracy, Justice and the Rule of Law emphasises strengthening the protection of political candidates and elected representatives facing growing threats and undue pressure.

This violence occurs in various forms, including sexual and physical threats and assaults, harassment, character assassinations, hate speech, disinformation campaigns exploiting misogynistic or anti-LGBTIQ narratives and deceptive image manipulation. With technological advancements, the methods of violence and harassment have moved online and become increasingly sophisticated and viral, exemplified by phenomena like cyber pile-on harassment and deepfakes. Their consequences, however, extend to the physical world, causing physical and psychological harm, as well as impacting professional and personal reputations, quality of life, and family. Proposals should, therefore, explore the wide range of impacts, including the chilling effect on victims, such as their withdrawal from social media public debates or public offices, including political ones. As situations of social, economic or political instability can exacerbate GBV and LGBTIQ-phobic violence, proposals are encouraged to explore how crises affect the nature, prevalence, and prevention of these types of violence, as well as victims’ access to support and justice.

Both political and media spheres, including radio, television, print, and online platforms, play a key role in shaping societal norms. Yet, coverage of GBV and cases of LGBTIQ-phobic violence are often sensationalised and biased, particularly when it involves public figures. For instance, little is known on how fictional and non-fictional narratives influence public awareness and perceptions of violence against politically active women and LGBTIQ people. Such gaps can lead to inadequate responses and support systems, while reinforcing gender stereotypes and contributing to victim blaming. Proposals should gather data on this impact and counteract sensationalism and misogyny to position media as driver of positive change. Proposals should also include analysis of the impact and potential gaps of existing EU legislation such as the Digital Services Act, and provide recommendations to policymakers.

Proposals are encouraged to explore cultural beliefs and practices, considering fields such as cinema and literature alongside social media platforms to explore how cultural representations and national context influence perceptions and responses to intersecting violence.

In addition, given that politically motivated violence, GBV and LGBTIQ-phobic violence intersect with various forms of discrimination, including racism 20 , proposals must consider at least three intersecting factors, such as disability, racial or ethnic background, age, religion or belief or other relevant intersecting dimensions. An intersectional lens is key to understand how the perpetration and experience of violence, including to report and access support, vary according to social, economic and identity-related characteristics of victims and perpetrators.

A multi-country approach using quantitative and qualitative data is key. Proposals should draw on a range of relevant disciplines (including SSH), and engage stakeholders, civil society organisations and individuals directly affected by the issues in the design and implementation of research activities. Engaging men and boys in preventing violence and challenging norms should be an integral part of the research. This could include exploring how arts and humanities approaches can foster critical reflection on gender norms, violence and discrimination.

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud (EOSC). Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

Proposals are encouraged to identify other relevant EU-funded projects, and to explore potential collaboration opportunities with them.

HORIZON-CL2-2026-01-DEMOCRACY-02: Understanding the forms of local democracy in low-income and low-middle income countries

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 21 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.EU institutions and national decision-makers are equipped with science-based tools, toolkits, training models, monitoring frameworks, and recommendations to proactively promote inequality reduction, human rights and democracy, in order to lead to more resilient and inclusive democratic societies in low-income and low-middle income countries 22

2.EU institutions and national decision-makers are better able to proactively promote democratic values, principles and practices in low- and low-middle income countries grounded in a better understanding of the actors at local level including their capacity and needs when engaging in democratic practices.

3.EU institutions, national decision-makers, and civil society organisations can access and use (evidence-based) good practices for working in fragile contexts 23

4.EU institutions and national decision-makers understand the role of decentralization processes in low-income and low-middle income countries, and its impact on the quality of public services and on acceptance of democratic processes among citizens.

In addition, projects should contribute to at least one of the following expected outcomes:

1.Policymakers, public authorities, and service delivery providers have a better understanding of the link between efficient delivery of public services and pro-democratic sentiment in low-income and low-middle income countries.

2.Civil society organisations, and other relevant actors, working in the fields of development cooperation and promotion of human rights have better tools to promote democratic practices at local level in low-income and low-middle income countries.

Scope: Democratic backsliding and human rights rollbacks are increasing globally, especially in low- and middle-income countries, driven by internal instability and external interference promoting non-democratic models. These trends also represent a risk to the security of European citizens and businesses, and a destabilisation factor in the countries and regions with which the EU maintains diplomatic and economic relations. To tackle this, the EU has developed and started to implement several strategies to promote and defend democracy and human rights in third countries 24 .

Developing countries with strong local democratic practices, such as elections and representative democracy at levels below the national government, tend to be more resilient against democratic backsliding. Proposals should therefore gather evidence on how actors in economic, political, and social ecosystems at the local level could foster democratic practices, increase citizens' trust in governance and democratic institutions, improve transparency of decision making, and promote respect for human rights. Proposals are also encouraged to gather evidence on different forms of democratic participation and governance at local level, paying particular attention to the inclusion of women and marginalised and underrepresented groups.

In countries where central governments face significant territorial challenges and lack effective control over certain areas, the EU and Member States are left to cooperate with administrations at sub-national levels. In these cases, the objectives of the research projects may be achieved through the consultation and engagement of local administrations and civil society partners. Proposals are encouraged to investigate how EU and national public authorities can operate in these fragile contexts, where central governments do not have sound control of areas of the country.

In addition, proposals are encouraged to investigate the link between efficient public service delivery and pro-democratic sentiment, experiences, and outcomes (measured, for example, by civic participation or trust in institutions), deliver a critical analysis of the evidence collected and identify good practices, conditions and methods for their transferability to other contexts.

Research activities should meaningfully involve a wide range of stakeholders and societal actors at local level (public authorities, economic and institutional actors, trade unions, traditional and faith leaders, indigenous people, women’s and LGBTIQ groups, and others), including non-scientific and non-academic actors. Proposals are encouraged to involve entities in low- and middle-income countries, to rely on their first-hand competences to steer the methodological approach and perform the data collection and analysis. Proposals are also encouraged to make use of participatory research approaches to enhance inclusivity and stakeholder engagement and experimental methods. They should adopt a multidisciplinary approach, integrating SSH fields such as political science, public administration, economics, cultural studies, sociology, gender studies, geography.

Proposals are encouraged to identify other relevant EU-funded projects, and to explore potential collaboration opportunities with them.

Given the geographical scope of this research, international cooperation is strongly encouraged. Proposals are encouraged to foster collaboration with entities in alignment with the New EU Agenda for EU-Latin America and the Caribbean, New EU Agenda for EU-Latin America and the Caribbean, EU–Central Asia Strategy, and AU–EU Innovation Agenda.

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud (EOSC), as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

HORIZON-CL2-2026-01-DEMOCRACY-03: Government in transition – how governments change the way they work and prepare the civil service for the future

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 25 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes.

1.Country government innovation info sheets, trends, inspiring good practices, the most innovative solutions recently developed or work in progress for next-generation governance and future-informed public decision making in EU Member States and Associated Countries (MS/AC).

2.Policy recommendations for both EU level and MS/AC level actions on adopting new governance paradigms, and strategies for enhanced (technical and financial) support for internal government innovation efforts.

3.Publication of lessons learned to enlighten government officials and the public about the often-invisible internal innovation strategies and impactful solutions in national governments.

4.A comprehensive MOOC (Massive Online Open Course) for government officials with relevant examples and cases.

5.Fostering of closer ties and collaboration among MS/AC (and any other relevant actors) to leverage national capabilities in innovative governance and maintain peer learning through e.g. relevant networks and knowledge exchange platforms.

Scope: In an era characterized by numerous concurrent crises, accelerated technological development, and waning public trust in government, the pivotal objective of this topic is to furnish a precise depiction of the current condition of public service in MS/AC, highlight the substantial challenges governments are endeavouring to manage at the same time, the general state of the civil service and the evolution of related public employment management, including HR policy, the organizational framework conditions conducive to innovation and agile operations, and organizational development efforts. Enhancing government capacities to define strategies and develop complex public policies in a swiftly evolving context is imperative. Traditional methods are increasingly ineffective, necessitating a reinvention of government operations.

This investigation intends to shed light on the disruptions currently reshaping the work of governments, the complex tasks they are grappling with, their internal innovation efforts and change processes little known by the public, and to showcase the immense investment and good practices governments developed and are developing to deal with their core business in radically new ways. Governments take various paths that best suit their ambition, vision, leveraging power and the characteristics of their national context.

Proposals are expected to cover all three focus areas detailed below:

1.New governance paradigm: Focus on new governance approaches and reforms in response to declining public trust, from preparation for crisis to anticipatory governance, agile leadership, using an innovation portfolio approach to strategic planning, working with the innovation ecosystem in strategic decision-making, the impacts of digital technology (especially the role of AI, automation, the redefinition of tasks, related opportunities and threats,), open government approaches, democratic participation and central communication strategies, information flows (including social media), and related civil service development governments undertake to stand the ground today and to prepare for tomorrow.

2.Innovative approaches to public service and policy development: Solving complex issues needs multidisciplinary (including from SSH disciplines) and innovative approaches to high-quality public service and effective administrative delivery, policy- and decision making, such as citizen participation, stakeholder engagement, systems thinking, role of technology/AI and interconnected data systems and experimentation (i.e. evidence-informed policymaking).

3.New public employment management and civil service empowerment: Enabling governments to explore possibilities and transforming the civil service through innovation and public intrapreneurship, HR policy, including a public administration health-check, and capacity building (e.g. upskilling, reskilling, future literacy), the organizational framework conditions (also sensitive to the needs of the next generation of civil servants) conducive to innovation and building resilience, and cooperation with other EU governments (data exchange, mutual support) while building a modern, future-ready civil service.

While national governments in the EU and Associated Countries are the primary focus for this investigation, regional and local governments as well as documented, highly inspirational good practice cases from the global context are of interest to learn from.

This should give voice to the civil service, examining how civil service officials (in various roles, functions and level of decision making, and in their diversity, including gender, age, socio-economic background, experience level, and other relevant personal characteristics) see the changing role of the state, their own role, organizational framework conditions (i.e. people, knowledge, ways of working, and rules and processes), how they cope under the current pressures, and what their visions, hopes and needs are for the future.

The research should build on existing work (data, reports, case studies, networks) by EU institutions, international organizations (World Economic Forum, OECD, United Nations, Chandler Institute of Governance, etc.), schools of governance, national governments and innovation agencies in EU Member States and Associated Countries, complemented by primary data to be collected through large-scale surveying, in-depth interviews, strategic reflection workshops covering key issues in the public governance domain (e.g. the core tasks of government, internal innovation strategies, regaining citizens’ trust, etc.), and key stakeholder engagement. The proposals should elaborate on the planned collection and analysis of the primary data (beyond desk research), and on the proposed engagement with senior officials in national government, at European level and international organizations (as relevant), demonstrating deep reach into the national civil services as key factors for the successful delivery of the work.

Proposals are encouraged to take stock of the uptake of provisions of Commission Communication COM(2023) 667 26 , and seek complementarity with relevant EU-funded projects, the OECD Observatory of Public Sector Innovation, and the relevant work of the Joint Research Centre of the European Commission.

HORIZON-CL2-2026-01-DEMOCRACY-04: Sustainable paths to media viability

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

In order to achieve the expected outcomes, consortia must include, as beneficiaries or affiliated entities, at least one news media organisation 27 .

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 28 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Reinforced digital transformation of the news media industry by facilitating the development of new business models, contributing to a more resilient and inclusive democracies.

2.Citizens, particularly those facing systemic disadvantages, are empowered and better equipped to make informed decisions, and news media’s role as contributor to a healthy, reinvigorated and fair democracy is enhanced.

3. Stronger engagement with emerging media creators (such as influencers and other online content producers) to promote transparency and accountability in their role in sharing information, and to foster reliance on trustworthy media sources.

Scope: Democracies are at risk when reliable and independent journalism is at risk. Yet, in order to be truly independent, media need sustainable financing models. At present, journalistic newsrooms are under severe economic pressure. Social media forces them to compete for citizens’ attention with other forms of infotainment, which sometimes entail unverified opinions and low-quality or malicious sources. To promote a well-informed democratic debate, citizens must be able to distinguish quality journalism abiding by professional standards, from opinion pieces and other forms of content, as free speech can thrive in ecosystems that enhance access to verified information and empower citizens to recognise it. Such ecosystems need to help distinguish sources that apply journalistic principles, including methods to ensure accuracy, independence, objectivity, impartiality, inclusivity and plural viewpoints.

To compete in the digital age, European media need to embrace innovation. The Commission’s 2023 European Media industry outlook 29 signalled that “an early adoption and usage of new technologies is key to adapt and open new markets”. Thus, applicants are invited to work together with news media organisations from the start to enhance innovation across the news media sectors, including by designing industrial and user-driven applications, on areas and aspects such as:

a) development and take up of methods to recognise content produced with journalistic standards (e.g. through trust indicators, browser plugins, etc.), to categorise such content (e.g. through industry-led crawlers, common taxonomies, metadata standards, etc.) and to promote such content (e.g. through inclusive and transparent news-oriented algorithms, recommender systems that show multiple views and prioritise quality information);

b) identification of AI models that can help media build attractive services (e.g. chat bots, search tools, aggregators) and other relevant models which can generate revenues (e.g. dynamic paywalls, advertising, copyright revenues, etc.);

c) innovative methods to ensure user-centric design and user engagement strategies, in compliance with journalistic standards;

d) roll-out of these models and methods towards the development of truly pan-European innovative platforms and/or interoperable standards within the project lifetime;

e) initiatives to federate media industries along a joint innovation agenda.

Innovation projects should focus on concrete ways to help journalistic content serve democracy by addressing aspects such as:

1.ensuring that journalistic content remains economically viable in AI-intermediated information spaces;

2.ensuring that journalistic content retains relevance and prominence in AI-driven search tools and future information ecosystems in Europe;

3.ensuring that algorithms based on journalistic standards (such as accuracy and inclusion) are developed enhancing professional journalism and preserving a trustworthy information ecosystem;

4.making sure that citizens are presented with multiple views online to make well-informed decisions;

5.development and integration of journalistic trust indicators in recommender systems, browsers and/or European news aggregators;

6.take-up of recommender systems that prioritise trusted sources and professional journalism;

7.development of better digital advertising business models for news producers, through proprietary systems that offer more brand safety and sufficiently detailed feedback to advertisers through joint metadata and audience measurement tools;

8.development of EU-level business case studies, explaining their impact on creation of advertising revenues, subscription revenues, etc.;

9.development and adoption of prototypes for recommender systems, proprietary crawlers, proprietary metadata generators, paywalls, advertising systems or other revenue-generating systems that can strengthen the economic viability of journalism.

Proposals are encouraged to investigate the behavioural dimensions of news consumption, focusing on how reader habits, trust, and perceptions influence engagement with journalism. This may include examining the role of behavioural science in designing interventions (such as nudges, gamification, or educational tools) to counter misinformation and strengthen critical thinking among audiences. Proposals are also encouraged to explore the evolving trust dynamics between human-curated journalism and AI-driven news delivery, addressing how public perceptions of reliability, bias, and transparency differ across these sources.

Where relevant, proposals are encouraged to investigate the need for transparency and accountability mechanisms for influencers and content creators who rely on media content in their work. This may entail advocating for clear disclosure of sources, partnerships, and potential biases, as well as fostering collaboration between content creators and media actors, to amplify the visibility and credibility of reliable information sources, ensuring audiences are informed by fact-based, ethically produced content.

Projects are encouraged to involve the relevant parts of the news media ecosystems to ensure take-up of the proposed models. All news media segments are eligible under this action (public, private media, sectoral media, etc) and collaboration across segments and across borders is encouraged. The participation in the consortia of research and academic actors from relevant disciplines, such as information science and media studies, as well as tech companies (e.g. ad-tech or other) to build workable prototypes, and SSH, is strongly encouraged. Where applicable, applicants should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud (EOSC), as well as data from relevant Data Spaces.

Clustering and cooperation among the selected projects under this topic are strongly encouraged.

HORIZON-CL2-2026-01-DEMOCRACY-05: Research and Innovation Network for a Union of Equality

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.00 and 4.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 4.50 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 30 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Policymakers are made aware and are equipped with the knowledge and tools to integrate inclusive and intersectional perspectives into their policymaking, which strengthens their capacity to promote and protect democracy, fundamental rights, and EU values.

2.Researchers gain insights on how to translate their findings on intersectional inequalities and democracy into actionable, evidence-based recommendations, enabling them to effectively inform policy and practice at local, regional, national, and EU levels.

3.Innovative solutions developed under Horizon Europe and other EU-funding programmes empower equally all citizens, to participate in democratic processes and decision-making.

Scope: This call topic aims to establish a Research and Innovation Network for a Union of Equality. The proposed network should bring together academic institutions, public bodies and civil society organisations to collaborate and promote the advancement of inclusive, equal, and resilient democratic societies.

The proposed network should contribute to the development of a comprehensive approach to democracy, fostering a culture of participation and inclusivity, and promoting the EU values of equality, justice, and human rights. It should also address how equality and intersectionality are defined across the EU’s diverse socio-political landscapes to ensure inclusive policies that account for varying cultural and social contexts. It could also reflect on how to foster the implementation of EU strategies under the Union of Equality. 31

The network should support the implementation of gender-inclusive and intersectional strategies to counter disinformation, reduce societal polarisation, and re-engage citizens in democratic practices. These efforts could also aim at promoting critical thinking, media literacy, and active civic participation across diverse groups including youth and underrepresented groups. The network could also leverage foresight to anticipate emerging challenges to democracy and inform effective policy responses. Its work should be informed by close contact with elected representatives at local, regional, national and EU levels.

As soon as possible in the network’s lifecycle, a dedicated online platform should be established to share evidence-based recommendations and innovative solutions to strengthen democratic practices based on Horizon Europe projects’ results and other relevant sources. This platform should be backed by a comprehensive repository that gathers information on existing tools, trainings, data, including disaggregated data, and methodologies for gender mainstreaming and addressing intersectional inequalities. It could also include a collaborative webpage for stakeholders to share information on events, calls for papers, and funding opportunities related to inclusive democracy, gender equality, and intersectionality.

The network should ensure and support the translation of research findings (including from SSH disciplines) into actionable, evidence-based proposals, and to enable the development of practical and effective recommendations that drive positive change at different level of actions (local, national, supranational). Living labs and innovation hubs could be used to provide a collaborative environment for stakeholders to co-create and test solutions.

To foster collaboration and drive progress, the network should host an annual thematic forum, providing a platform for stakeholders and policymakers to meet in person and share innovative ideas, receive feedback, and learn from one another.

As a research and innovation area where freedom of science is enshrined and protected, the European Union offers an ideal environment to advance a career. Therefore, the network should also explore how to ensure a safe and enabling research environment, protecting researchers from backlash, hate speech and harassment, and promoting academic freedom and integrity when researching on democracy, inclusive societies, and intersectionality.

The network’s actions should contribute to ensuring that the results and innovations generated by Horizon Europe projects related to inclusiveness in the public space, democracy, and governance are taken up and made available to relevant stakeholders. It could particularly build on past and on-going EU-funded projects, such as those under the topics HORIZON-CL2-2021-DEMOCRACY-01-03, HORIZON-CL2-2022-TRANSFORMATIONS-01-05; HORIZON-CL2-2022-TRANSFORMATIONS-01-08 and HORIZON-CL2-2024-DEMOCRACY-01-05. Proposals are encouraged to identify other relevant EU-funded projects, and to explore potential collaboration opportunities with them.

The action to be funded should have a minimum duration of 4 years.

HORIZON-CL2-2026-01-DEMOCRACY-06: Governing global commons sustainably

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering the topic’s different thematic areas, grants will be awarded to applications not only in order of ranking but at least also to those that are the highest ranked within each area provided in the scope (areas A, B, and C), provided that the corresponding applications attain all thresholds. Proposals should clearly indicate the thematic area(s) they have selected to work on.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 32 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.EU institutions, Member States and decision-makers worldwide, relevant international organisations, civil society organisations and other societal actors have a better shared understanding of the systemic challenges and the underlying drivers and motivations that undermine managing global commons sustainably.

2.EU institutions, Member States and decision-makers worldwide, relevant international organisations, as well as academies of science, higher education institutions and research-performing organisations are better equipped with the tools needed to improve the science-policy interface in the area of foreign and security policies in general, and multilateral / national science advisory bodies in the field of foreign policy in particular with a recognition of the need to engage citizens in a more participatory and inclusive approach to research and policy-making.

3.Rules-based multilateralism is strengthened by the development of concepts, methods, processes, and information relevant for decision-making that foster the sustainable governance of global commons within the evolving geopolitical context, thereby informing also the EU’s science diplomacy actions.

Scope: Global commons—resources shared by all humanity—are increasingly threatened by overuse and degradation by state and non-state actors. Spaces beyond national jurisdiction, in particular, require collective management to ensure sustainability for future generations. Not doing so will deepen the triple planetary crisis of climate change, biodiversity loss and pollution, and possibly lead to cascading and compounding effects and crossing irreversible tipping points and planetary boundaries. Evolving geopolitical tensions, weakened multilateral cooperation, technological advances, and rising commercial interests from non-state actors, have intensified pressures on global commons. Declining trust in science further complicates efforts to agree on their fair and sustainable governance, risking instability and conflict.

Against the current geopolitical background, there is a need to review the effectiveness of existing legal instruments and to accompany with research the implementation of new instruments. In addition, there is a need to further enhance the impact of existing and evolving science-policy fora 33 and their links to relevant conventions and agreements. To this end, proposals should perform a comprehensive mapping of actors’ motivations and values on societal, corporate and state level that covers different regions and coalitions of countries around the world 34 .

Research is also needed into how the current governance of global commons affects intergenerational justice and human rights, including gender equality and the impact on different social groups, and how civil society can be enabled to access information, provide knowledge (including Indigenous Peoples and Local Communities knowledge), and participate in the governance of global commons. This may include conducting research aimed at enhancing citizen engagement and trust in governance processes and efforts, exploring motivations and drivers underlying stakeholder positions in multilateral fora. Proposals are also encouraged to study the rights of appeal and redress in policies related to the global commons, including but not limited to the “rights of nature”.

The underlying question is how a sustainable governance of global commons can look like in a multipolar world with competing hegemonic powers that do not necessarily share a common understanding of the merits of cooperation, multilateralism, or even international law. Hence, the overall aim of this call is to develop multi- and interdisciplinary concepts and solutions for governing the global commons sustainably, including through the use of science diplomacy as a soft power and by learning from best practices in the different types of commons, such as the Ocean, Antarctica and Outer Space.

Proposals are encouraged to explore how imbalances in the governance of global commons may contribute to geopolitical tensions, including the outbreak of direct conflicts or proxy wars, as well as the erosion or violation of human rights. They are also encouraged to consider the wider implications of such governance gaps for international stability and the rules-based global order.

Proposals are expected to address one of the following thematic areas:

Area A: Climate governance. Projects should consider past and current global climate governance efforts, including the United Nations Framework Convention on Climate Change and the Paris Agreement, and develop insights for strengthening climate governance, considering the current geopolitical context. Specific attention should be given to analysing the drivers underlying the reproduction of diverging positions towards climate change among stakeholders and possible solutions as well as reinforcing the role of science-policy interfaces such as the IPCC and other relevant science-based mechanisms, e.g., through enhanced citizen engagement to increase trust. Proposals should inform and develop recommendations for EU and global science diplomacy action.

Area B: Biodiversity governance. Projects should consider past and current global biodiversity governance efforts, including the Convention on Biological Diversity, related Conferences of the Parties and their subsidiary bodies, and the Kunming-Montreal Global Biodiversity Framework (GBF). Projects are encouraged to examine in particular the integration of rights of appeal and redress in environmental decision-making processes, including legal mechanisms to address grievances and ensure accountability, particularly in the context of the “rights of nature” and other innovative approaches to environmental justice. Taking into account the current geopolitical environment, projects should develop options for reinforcing the role of science-policy interfaces such as the IPBES, IPR and other relevant science-based mechanisms, including the Global Knowledge Support Service for Biodiversity and the Subregional Technical and Scientific Cooperation Support Centres, with the aim of informing and developing recommendations for EU and global science diplomacy action. This should include a focus on enhancing access to environmental information for citizens and civil society organisations to empower biodiversity action, as well as mainstreaming gender equality and human rights considerations into biodiversity policy frameworks, in alignment with the work of the United Nations Human Rights Council (UN HCHR) on the development of human rights norms for biodiversity protection.

Area C: Governance of spaces beyond national jurisdiction. Projects should provide a cross-cutting assessment of how different types of spaces beyond national jurisdiction have been governed so far, notably the ocean, polar regions, outer space including the Moon, Low Earth Orbit, the use of the radio spectrum, and dark and quiet skies. This may include a comparative review of the legal frameworks (e.g., Antarctic Treaty, UN Convention on the Law of the Sea, High Seas Treaty, Outer Space Treaty, etc.). Projects should study in a holistic, multidisciplinary manner current and emerging pressures on these spaces, with specific emphasis on the role of non-state actors and develop approaches to governing these spaces sustainably despite geopolitical fragmentation, thereby informing EU science diplomacy action. Examples of application include, and are not limited to, the protection of deep-sea ecosystems, the management of space debris, or the preservation of a dark and quiet sky.

Research activities should meaningfully involve experts with practical experience in the relevant processes and bodies, including policymakers, diplomats, the business sector, academia, and civil society, including indigenous rights holders. Engagement with international partners is strongly encouraged. Involvement of the EU’s outermost regions is particularly welcome for area C. Research should have a multi-, inter- and trans-disciplinary systemic perspective, bringing together expertise across natural sciences and engineering as well as social sciences and humanities (including history, law, ethics, and other disciplines). The selected projects should cooperate with each other to foster synergies and links between the different governance frameworks. Proposals are encouraged to identify other relevant EU-funded projects and to explore potential collaboration opportunities with them.

HORIZON-CL2-2026-01-DEMOCRACY-07: Supporting post-conflict democracy and reconstruction

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 35 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.EU national and local policymakers develop and implement effective strategies for sustainable peace and democratic reconstruction in post-conflict areas, promoting stability, inclusivity, equity, security, human rights, and strengthening integrity and anticorruption measures to ensure transparent, accountable, and ethical use of reconstruction aid.

2.EU and national policymakers inform their decision-making with evidence-based recommendations on international cooperation, EU democracy support, and civil society engagement in post-conflict reconstruction, leading to more effective, inclusive and sustainable reconstruction efforts.

3.Local civil society organisations and community groups, with a focus on persons and groups in a vulnerable situation in post-conflict countries, provide guidance and support to educators, media professionals, public administrators, and other stakeholders on promoting reconciliation, accountability, and sustainable peace.

4.Specialised service providers, including NGOs and community organisations, offer support services and programmes to veterans and the persons and groups in a vulnerable situation affected by the conflict reintegrating them into democratic societies, addressing their socio-economic and psychological needs and promoting successful reintegration into civilian life.

Scope: The aftermath of conflict poses significant challenges for rebuilding democratic institutions, promoting social dialogue, and achieving sustainable peace. In conflict and post-conflict areas, the destruction of infrastructure, institutions, and social fabric can lead to prolonged instability, increased inequalities, human suffering, and a decline in democratic governance.

This research aims to investigate the complex relationships between post-conflict reconstruction, democracy, inequality, and international cooperation, with the ultimate goal of promoting reconciliation, accountability, and social dialogue in conflict and post-conflict areas. By analysing the causes and consequences of conflicts, examining the role of historical narratives and cultural sensibilities, and gathering evidence on key factors such as ethnic violence, inequalities, and conflict legacies, this research seeks to inform the development of effective prevention, resolution, and reconciliation strategies. Proposals are encouraged to examine the prevention of fractured transitions in post-conflict situations, assessing past, present, and future divisions, and incorporating intergenerational and transgenerational perspectives to address potential challenges and promote a more sustainable transition.

Research should have an interdisciplinary approach, drawing on insights from SSH disciplines such as contemporary historiography, sociology, psychology, legal, political science and cultural studies, to examine the complex economic, social, psychological and institutional factors that influence post-conflict rebuilding efforts.

Proposals should adopt a collaborative and interdisciplinary approach, bringing together a diverse range of stakeholders, including research institutions, specialized service providers, local authorities, civil society organizations, local actors, media and information providers, schools, educational organizations, cultural institutions and heritage institutes. In addition, particular could be brought to the role of women as peacebuilders 36 .This integrative approach should combine expertise and experience in areas such as conflict resolution, democratic governance, state rebuilding and social cohesion to explore new approaches to post-conflict reconstruction.

Proposals may incorporate participatory research approaches to enhance inclusivity and stakeholder engagement, and should also examine innovative methods, such as participatory governance, inclusive economic development, and community-led reconstruction, to identify effective strategies applicable in diverse conflict and post-conflict areas.

Proposals are encouraged to identify other relevant EU-funded projects related to EU democracy support, civil society engagement, and international cooperation on sustainable peace and democratic governance, and to explore potential collaboration opportunities with them. In order to achieve the topic’s expected outcomes, international cooperation is encouraged.

HORIZON-CL2-2026-01-DEMOCRACY-08: Electoral integrity in the digital context

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 37 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.EU, national and local policymakers possess the necessary knowledge to inform the development of election regulations, standards and tools that address the use of digital technologies in elections and political campaigns, ensuring their integrity, inclusiveness, accessibility, fairness, transparency, and security.

2.Organisations involved in electoral processes develop and implement guidelines for the responsible use of digital technologies in elections and political campaigns, aligned with EU and national regulations.

3.Enhanced transparency and accountability in AI-powered political campaigns, achieved through requirements for AI system audits, data disclosure, transparency regarding algorithms and sources of Large Language Models (LLMs), and responsible AI development.

Scope: The integrity of electoral processes in Europe is facing challenges in the digital age. The digital transformation of democratic processes has created new avenues for citizen engagement, but it also poses significant risks from disinformation to the integrity of electoral and other democratic processes. Concerns about foreign interference, exemplified by Russia's activities, but also other third countries, have underscored the need for robust measures to safeguard the electoral processes, including enhancing cybersecurity and voter verification to prevent perceived electoral manipulation. Social media platforms, in particular, have become increasingly critical battlegrounds in the fight for public opinion, with AI-powered tools being used to artificially amplify and spread disinformation, manipulate public discourse, and influence voter behaviour.

To address these challenges, it is essential to examine the effects of digital technologies on public opinion and governance, and investigate the development of ethical AI, transparent political advertising, and tools to counter misinformation, disinformation and foreign information manipulation and interference (FIMI). This includes exploring the potential of digital technologies to transform and improve democratic processes, investigating multi-stakeholder approaches, with particular attention in fostering dialogue with online platforms, media and political parties and movements, as well as strengthening the traditional and new media and securing alternative platforms to enhance electoral resilience.

Proposals should also investigate the risks new technologies pose to democratic integrity, particularly through the manipulation of public opinion and electoral processes, while also exploring ways to leverage these new technologies to better understand and mitigate these threats. Proposals are also encouraged to examine how AI-generated content across media, including entertainment media, influence public opinion, social narratives, gender stereotypes and norms, and civic engagement. Moreover, proposals may consider strategies for the implementation of appropriate cryptographic measures, including the investigation of approaches based on post-quantum cryptography.

The EU institutions have been actively engaged in addressing the key challenges for election integrity, including the artificial amplification of disinformation, online platform accountability, and the protection of democratic processes. Proposals should take into account ongoing political and strategic initiatives, notably the Political Advertising Regulation, the AI Act, the Digital Services Act (DSA) election guidelines 38 and the Commission’s 2023 Recommendation on inclusive and resilient elections, and Code of Conduct on Disinformation 39 .

The ultimate goal is to understand how to create robust and resilient electoral systems that can meet the challenges of the digital age, ensure the safety and integrity of electoral processes, and promote free, fair, inclusive, accessible and transparent elections. This requires investigating the risks of cyberattacks and foreign interference on electoral processes, developing strategies to enhance voting system security and promote election transparency, developing early warning systems, effective debunking strategies, and accountability measures for platforms.

Research should have an interdisciplinary approach (including SSH disciplines), bringing together a diverse range of stakeholders, including – but not limited to - electoral authorities and other national authorities with responsibilities in electoral matters – notably those represented in the European Cooperation Network on elections – civil society organisations, new and traditional media and digital platforms.

Projects may also focus on how FIMI can influence political discourse via digital platforms, particularly during electoral periods, including in ways that undermine the rights of women, LGBTIQ people, persons with disabilities and other underrepresented groups. This also involves examining the safety of electoral processes, protecting the integrity of elections, and maintaining public trust in the democratic process, with a particular focus on ensuring the safety and security of political candidates, especially women and LGBTIQ people and other members of minority groups, from violence, intimidation, and harassment. Addressing these concerns requires a comprehensive understanding of how AI shapes political campaigns, media narratives, public engagement, and the spread of (gendered) disinformation.

Proposals are encouraged to identify other EU-funded projects related to electoral integrity under the Horizon Europe programme (including but not limited to those in the fields of cybersecurity and research and development of AI), and complementary funding schemes, such as the Citizens, Equality, Rights and Values programme and the Digital Europe Programme, and to explore potential collaboration opportunities with them.

Applicants may consider the participation of the Joint Research Centre (JRC) to leverage its broad range of scientific and technical capabilities, including its expertise in digital technologies, data science, and cybersecurity, to support the projects’ objectives and enhance their overall impact.

HORIZON-CL2-2026-01-DEMOCRACY-09: Citizenship education as part of lifelong learning

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 16.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 40 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Policymakers, educators, and other relevant actors have tools and recommendations to put in place more opportunities for lifelong civic and citizenship 41 learning, in support of democracy and democratic participation, including by relying on the opportunities offered by digital means, notably civic tech.

2.Policymakers at local, regional, national and EU level have tools and recommendations for ensuring the participation of citizens in democratic life, whatever their background, especially those who face barriers to participation in democratic processes.

Scope: A healthy democracy relies on citizens being able to make informed democratic choices, in free and fair elections. Meaningful and inclusive citizens’ participation and engagement can further complement and reinforce representative democracies and foster trust in public institutions. Education plays a major role in supporting active interest in democratic participation and citizen engagement. Accessible education in matters of democracy and participation in public-policy making is a lifelong process that concerns all age groups in society regardless of their educational and socio-economic backgrounds.

Lifelong learning about democratic processes, civic rights and obligations is crucial. It is a long process that concerns not only young people but also older ones. A healthy democracy relies on meaningful, inclusive engagement from citizens across all ages and demographic groups on a continuous basis. It is important to sustain lifelong civic participation, as technological, geopolitical and economic changes pose new challenges to social cohesion and the equal participation of all citizens in democratic processes.

The focus of this topic is on how citizenship education as part of lifelong learning can boost citizens’ democratic involvement and civic engagement. Research should look at how vocational education and training (VET) (e.g. at secondary and post-secondary levels), including apprenticeships, or adult education programmes, can raise civic knowledge, political awareness, and attachment to democratic values, such as respect for human dignity, freedom, equality and the rule of law. Projects should examine either VET or adult education programmes. Research should further investigate how involvement in these programmes is linked to increased civic participation actions like voting or standing as a candidate in elections, engaging in public policy-making processes, or broader democratic participation such as volunteering or engaging with civil society organisations.

Research could also explore how VET or adult learning programmes could support citizens including persons with disabilities, in enhancing their digital and media literacy skills, and navigating and understanding the rapidly changing democratic information ecosystem, for example by being able to recognise disinformation and make use of digital tools for democratic engagement.

Research should test and pilot innovative methods and curricula to develop citizenship awareness for VET or adult education teachers and students.

A gender and intersectional perspective should be systematically integrated throughout the research, as well as the perspective of other groups that are marginalised, underrepresented in political decision-making, face barriers due to accessibility issues, or are at risk of disengagement.

Research may also examine digital and media literacy to foster critical thinking, to shape and develop citizens’ media and other competencies of citizens, and make recommendations for best practices in this area. Proposals may also examine democratic participation among ageing populations for whom digital tools are a barrier and propose recommendations for solutions to improve their participation. While digital tools can support engagement, research may also examine non-digital, person-to-person approaches that support participation, including in an inter-generational setting.

Proposals should seek collaboration with the European Partnership on Social Transformations and Resilience.

HORIZON-CL2-2026-01-DEMOCRACY-10: Digital and media literacy as drivers for democratic and civic resilience

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 42 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1. EU institutions and national decision-makers, have a better understanding of how to foster democratic resilience through media and digital literacy, equipping societies to adapt and thrive in the face of evolving technological, political, and societal challenges.

2.Citizens are empowered to navigate the digital landscape with discernment and critical thinking, actively engaging with media and other source of information, ensuring informed democratic participation.

Scope: As recalled by the “Safer together” report 43 , “over the past years, the Commission has already taken steps to counter hybrid threats (including foreign information manipulation and interference/FIMI) and enhance democratic resilience across the EU. It adopted, among other initiatives, the European Democracy Action Plan 44 to build more resilient democracies across the EU by promoting free and fair elections, strengthening media freedom, countering disinformation and FIMI and promoting information integrity. With the adoption of the Digital Services Act 45 (DSA) and its binding obligations for online platforms to combat the spread of disinformation, the Commission also strengthened the Code of Practice on Disinformation, which became a Code of Conduct within the framework of the DSA. Moreover, the launch of the European Digital Media Observatory (EDMO) and its hubs increased the capacity to detect, analyse and expose disinformation campaigns.” 46

The Preparedness Union Strategy 47 underlines how preparedness is a collective responsibility. It also points at the need to make our democracies more resilient, in particular in view of strengthening trust in institutions, which can be crucial in crisis situations as seen for instance during the COVID pandemic. Groups in a vulnerable situation in particular, such as children, senior citizens and persons with disabilities, ethnic or religious minorities, LGBTIQ people, those suffering poverty and/or social exclusion, are disproportionately affected by crises, often exacerbating pre-existing disadvantages, barriers and inequalities.

Disinformation is particularly harmful as it undermines public confidence and can exacerbate the impact of crises. Engaged, informed and empowered citizens are the best guarantee for the resilience of our democracies. Public authorities, schools, universities and training institutions, youth initiatives, civil society organisations and associations, social partners, businesses, local networks and communities, and citizens from an early age, all play a vital role in such collective endeavour, and the proposed research should take a multi-actor approach.

Against this background, the proposed research should explore the complex and dynamic patterns of user behaviours in the digital age, investigating how individuals seek, evaluate, and engage with information online, and offline. Such an exploration will benefit from including an analysis of the emotional dynamics in the dissemination of disinformation and polarization on digital platforms. This is especially relevant in crisis contexts in which foreign information manipulation and disinformation can be leveraged to increase panic and confusion. Proposals should investigate how algorithms amplify emotive content, fostering polarization and undermining trust in democratic institutions, as well as crisis response and develop digital and media literacy strategies to counter emotionally manipulative narratives, such as populist and post-truth discourses.

The research should also examine the factors that influence digital literacy, information-seeking habits, and online engagement, with a focus on improving citizen’s’ participation and engagement through digital means (including through civic tech) and informed decision-making. At a time when disinformation is used to sow discord by exploiting the fears of citizens, it is crucial to ensure that democratic decisions are informed by the most reliable and widely accepted facts and sources of information available. Research should explore the critical role digital and media literacy can play in fostering societal resilience and information integrity, by allowing citizens to navigate and resist misinformation and disinformation.

Proposals should plan a critical assessment of media and digital literacy initiatives 48 to assess whether existing efforts are enhancing citizens’ resilience, or whether new approaches are needed to more effectively equip citizens against evolving manipulation tactics.

Research should identify strategies to improve media literacy and digital and media literacy, in order to enhance critical thinking, promote evidence-based decision-making, and counter the negative impacts of disinformation on democratic societies. To facilitate the generation of practical solutions for educators and policymakers, the research could utilise computational tools, such as Social Network Analysis and Natural Language Processing, to map and mitigate the dissemination of disinformation across multiple platforms. This includes identifying Coordinated Inauthentic Behaviour and analysing both textual and visual content to inform media literacy initiatives.

Proposals are encouraged to identify other relevant EU-funded projects related to media and digital literacy, and to explore potential collaboration opportunities with them. Clustering and cooperation with other selected projects under this topic and other relevant projects are strongly encouraged.

The projects selected for funding are encouraged to collaborate with the JRC to seek synergies with its work on innovation for democracy and public governance.

HORIZON-CL2-2027-01-DEMOCRACY-01: Advisory support and network for countering and preventing radicalisation, extremism, hate speech and polarisation

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 3.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.50 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Due to the scope of this topic, legal entities established in non-associated third countries may exceptionally participate in this Coordination and Support Action as a beneficiary or affiliated entity and are exceptionally eligible for Union funding.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 49 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Political, societal, educational stakeholders, and researchers have an improved understanding of theoretical models and provided pathways for implementing solutions to combat extremism, radicalisation, hate speech and polarisation.

2.Public authorities, law enforcement agencies, local authorities, NGOs, and community actors are more engaged in implementing and adapting solutions addressing radicalisation, extremism, hate speech, and polarisation in their respective contexts.

3.EU institutions, national policymakers and judicial bodies can draw on an enhanced evidence-base for their decision-making through scientific, political, and legal assessments of research results in real-life contexts, enabling replication of methods, legislative changes, and innovation.

4.Improved understanding of the root causes of hate and polarisation, of methodologies to combat online hate ecosystems and of the role of traditional media in shaping public opinion, including the correlation between media consumption and polarisation, to inform strategies for protecting victims and addressing hate crimes and speech.

Scope: The European Union has been actively working to combat racism, xenophobia, hate speech, hate crimes, and extremism in recent years, developing and implementing various strategies to address these issues 50 . Horizon 2020 and Horizon Europe have also played a crucial role in funding projects that aim to develop research and collect evidence on how to counter and prevent radicalisation, polarisation, hate speech and extremism. These phenomena pose significant risks, as they can undermine trust in democratic institutions, weaken the social contract, and contribute to rising inequalities and instability.

European research (including research by SSH disciplines) should combine a clear understanding of the mechanisms that play a fundamental role in the circulation of online hate speech, radicalisation, extremism, and polarisation with the development of strategies to prevent and counter these phenomena. At the same time, it should promote the Union values enshrined in the Treaty on European Union, such as human dignity, freedom, democracy, equality, the rule of law and respect for human rights, and the protection of democratic institutions, as a condition for everyone's talents to flourish and for fostering a cohesive society and a culture of tolerance and pluralism. This will contribute to enhance the prevention of violent extremism, hate speech and hate crime and the promotion of a more inclusive and resilient society.

The spread of hate speech and extremist ideologies online has become a major concern, and the need for effective solutions to address these issues is pressing. Hate speech and extremism can be criminal offences, but also more broadly contribute to polarisation and have a chilling effect on freedom of expression, also limiting the engagement of individuals in public life (e.g. elected officials stepping down from elections because of hate attacks). Moreover, the polarisation of society and the erosion of trust in institutions pose a threat to social cohesion and democratic values.

To address these challenges, it is essential also to foster the understanding on the root causes of radicalisation, extremism, hate and polarisation, including as concerns the impact of socio-economic factors. This requires also collaboration with end-users, such as civil society organisations and practitioners 51 , who can provide valuable insights and help develop solutions that are tailored to their specific needs and contexts.

Proposals are encouraged to identify other EU-funded projects related to preventing radicalisation, extremism, hate speech, and polarisation, financed by the Horizon programmes (Horizon 2020 and Horizon Europe) and complementary funding schemes (such as the Citizens, Equality, Rights and Values Programme, the Internal Security Fund, or others) and to explore potential opportunities for collaboration with them. Proposals should integrate a gender-sensitive and intersectional approach to illustrate how radicalisation, extremism, hate speech and polarisation disproportionately affect different groups and groups of different ages.

Initiatives of research such as the ones in the EU Knowledge Hub on Prevention of Radicalisation 52 (previously Radicalisation Awareness Network) or the forthcoming online knowledge hub under the Code of conduct on countering illegal hate speech online should be considered when developing initiatives to upscale and exploit solutions to combat extremism, hate speech and radicalisation. Research activities should meaningfully involve a wide range of stakeholders and societal actors, particularly civil society organisations, including non-academic and non-scientific actors. Projects should link appropriately with the envisaged European Centre for Democratic Resilience and seek to make best use of its stakeholder platform.

HORIZON-CL2-2027-01-DEMOCRACY-02: Women’s, LGBTIQ and minority rights in a context of autocracy, conflict and geopolitical shifts

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 53 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Policymakers, public administrations, human rights organisations, and civil society actors have strengthened mechanisms to protect groups in a vulnerable situation (such as women, LGBTIQ people, persons with disabilities and minorities) in contexts of autocracy, conflict, and geopolitical instability.

2.Researchers and data collection bodies benefit from robust methodologies to systematically document and analyse the impact of democratic backsliding, conflict, and geopolitical shifts on the rights of these specific groups in a vulnerable situation.

3.Civil society organisations and grassroots movements have enhanced their resilience and advocacy strategies, thanks to the identification of best practices and innovative approaches to counter repression, expand civic space, and promote inclusive governance, including in authoritarian or conflict settings.

Scope: Autocratic regimes, armed conflicts, and global geopolitical shifts pose significant threats to fundamental rights. These challenges manifest in the rollback of legal protections, increased political violence, shrinking civic space, and targeted discrimination, both offline and online. In this context, a deeper understanding of the disproportionate impact of these crises on different groups is key to developing more targeted and effective policies.

The proposed research should examine the intersection of age, gender, sex, sexual orientation, minority status, or migratory background, in contexts of democratic erosion, authoritarian governance, and geopolitical crises. It can focus on one or multiple groups in a vulnerable situation, such as women, LGBTIQ people, ethnic and/or religious minorities, people with disabilities, children or the elderly. Case studies could be selected to reflect a wide range of geopolitical contexts, including regions undergoing democratic erosion, post-conflict reconstruction, or consolidation of authoritarian rule.

The proposed research should analyse how legal and institutional frameworks are weaponised and leveraged by authoritarian actors to restrict rights, the role of civil society in resisting repression, and the impact of digital surveillance, algorithmic discrimination and online disinformation in targeting specific groups in a vulnerable situation.

Particular attention should be given to the restricted access to sexual and reproductive health rights during crises, armed conflicts, and geopolitical shifts, as well as the prevalence of gender-based violence (GBV). In such contexts, GBV can be frequently used as a coercive tactic, reinforcing discrimination and reversing progress on gender equality. Hate-motivated violence can become even more complex when directed at women and groups in a vulnerable situation, further limiting their access to humanitarian assistance and undermining their fundamental rights. Therefore, the proposed research should develop prevention and response strategies for public administration, law enforcement, and military bodies to combat GBV effectively in crisis situations.

Proposals should take an interdisciplinary approach, combining SSH disciplines with insights from computer science and data analytics. They should integrate a strong data-driven approach and could explore aspects such as:

1.Mapping and measuring the compounded effects of conflict, forced displacement, and democratic backsliding on access to rights, services, and political participation.

2.Developing new methodologies and indicators to assess the impact of shrinking civic space and legal rollbacks on gender and minority rights.

3.Creating data-driven tools or policy dashboards to monitor the evolving risks faced by women, LGBTIQ people, and/or various minority groups in authoritarian and post-conflict settings.

Proposals should adopt a multi-scalar approach that connects grassroots-level experiences of discrimination and exclusion with macro-level geopolitical, legal and policy frameworks. Proposals could assess how international and European actors can effectively counter these trends through diplomatic efforts, development cooperation, and targeted support for civil society. Engaging with policymakers, human rights organisations, and affected communities is essential.

Proposals are encouraged to identify other relevant EU-funded projects, notably in cluster 2 and 3, and to explore potential collaboration opportunities with them. In order to achieve the topic’s expected outcomes, international cooperation is encouraged.

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud (EOSC), as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

HORIZON-CL2-2027-01-DEMOCRACY-03: Student and family engagement for developing a culture of democratic/civic participation

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 54 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Policymakers, education and training institutions, and educators will be provided with an evidence base, toolkits, and recommendations on the types of collaboration mechanisms with families that are most effective in supporting schools' efforts to provide citizenship education 55 .

2.Policymakers, education and training institutions, and educators will have a deeper understanding of the effectiveness of student councils and other student participatory mechanisms on influencing school decision-making and on student civic engagement.

3.Policymakers, education and training institutions, and educators will have a deeper understanding of the impact of family involvement in citizenship education in schools.

4.Educators have frameworks, guidance, and tools for evaluating social-emotional learning, including values and attitudes, as part of citizenship education.

Scope: Research should examine schools as a locus for practicing participation and developing innovative participatory practices.

Research should examine student and family engagement to foster a democratic culture via school activities. It should consider schools as social places for intergenerational dialogue.

Research should examine the role of socio-emotional learning in tackling sensitive topics in the classroom and in fostering civic agency development among learners. Research could explore the emotions that drive civic engagement and investigate strategies to help students emotionally cope with frustrations when their civic engagement efforts do not unfold as expected. Research should integrate an intersectional approach that is sensitive to gender and ability, by studying how students contribute to and respond to civic engagement efforts differently according to their identity and backgrounds.

Research should examine the active role of families in building children and young people's civic identity. Parents/caregivers and the wider family are key in children and young people’s informal learning, shaping their interests, values, and world-views; family involvement in school citizenship education might vary in more diverse communities, depending on the family’s cultural, migrant or socio-economic backgrounds; some families may not appreciate the importance of teaching about social issues, democracy, or civic participation or may feel excluded or disconnected from schools’ efforts to provide citizenship education. Research should examine how citizenship education is reinforced or challenged outside the classroom, especially with growing polarization and diversity of our societies. The research should provide recommendations of how to effectively engage families from diverse backgrounds in their children's citizenship education. The main focus should be on parents and caregivers (legal guardians); exploring other wider family influences is also possible.

Research should examine families’ and students' views on the content of citizenship education and examine the role of curriculum design in promoting inclusive civic engagement among students from diverse backgrounds. Arts and humanities can be part of the disciplines examined where relevant. Research should aim to identify the types of collaboration that not only bolster students' civic competence but also ensure inclusivity in their engagement.

The research should investigate the effectiveness of student councils and other participatory mechanisms in providing meaningful opportunities for student influence. Research should investigate the incentives and motives behind participation and uncover possible restrictions and motives for non-participation. It should exploit the tools that have been already developed in previous research projects in the area of civic participation.

Research should address the lack of formal monitoring and evaluation of these participatory mechanisms. It should develop frameworks, guidance, and tools for evaluation of socio-emotional learning, including values and attitudes as part of citizenship education.

Research can explore whether and how engaging families in citizenship education and fostering of a democratic culture at school influences both the civic participation of children and young people, and that of their families. Emphasis could be placed on schools in marginalised areas or with high migrant populations, to uncover structural barriers to civic engagement in those settings.

Research should include pilots or living labs, developing innovative participation practices in schools, where students learn to recognise and exercise their citizenship rights and obligations, strengthen the value of democracy, and build their identity as active citizens. Projects should collaborate with schools and education authorities in the development and running of these pilots and living labs.

Projects may freely choose the age group they will examine, as long as it remains within primary and/or secondary education levels.

HORIZON-CL2-2027-01-DEMOCRACY-04: Addressing the impact of artificial intelligence, cyberviolence, and deepfakes on equality, democracy and inclusive societies

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 20.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 56 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Enhanced understanding of the impact of AI-driven technologies, including AI-generated deepfakes and automated content generation on equality, political participation, democratic processes, public trust, and social cohesion, with evidence-based insights into their role in mitigating or exacerbating disparities.

2.Uptake of evidence-based policy frameworks for responsible, trustworthy, and transparent AI governance, integrating ethical, legal, and societal considerations to safeguard fundamental rights, mitigate risks of disinformation, and ensure fair and safe AI deployment, in line with the obligations set out in the EU Regulation on artificial intelligence 57 .

3.Increased public awareness and media literacy to empower citizens to identify and critically assess disinformation, use of deepfakes for malicious purpose, and online harm, alongside the uptake of evidence-based tools for preventing, detecting, and mitigating these harms.

4.Strengthened capacity of academic institutions to conduct societally relevant AI research and drive the development of trustworthy, ethical AI models, enabled by increased academia-industry collaboration and better access to e.g., computing infrastructure, high-quality datasets, collaborative tools, and funding.

Scope: The rapid development and deployment of AI technologies, along with their malicious use such as the creation of artificially generated and manipulated content,, profoundly impacts democracy, equality, social inclusion, and knowledge production, and contributes to the rise of cyberviolence. Although AI can offer many opportunities, its misuse can facilitate/amplify inequalities and power imbalances, spread misinformation and cyberviolence against women, children and minorities, concentrate data control, and undermine democratic processes. Hence, this topic addresses both the malicious use of AI (e.g. AI-generated disinformation, deepfakes, cyberviolence) and its unintentional societal consequences (e.g. algorithmic opacity, amplification of bias).

AI’s role in media influence and public trust demands urgent attention, as the rise of AI-generated or manipulated content, including deepfakes, threatens democratic processes and epistemic rights. A key area of concern is how AI and artificially generated content is impacting cyberviolence, and the effect it has on individuals or groups who distrust democracy, particularly where this distrust intersects with far-left and far-right populism and foreign interference.

Proposals should explore how AI-driven technologies and their use may either exacerbate or mitigate 58 inequalities and discriminations based on sex, gender, sexual orientation, racial or ethnic background, religion or belief, age, and disability, particularly in access to information, decision-making, and representation. A critical analysis is needed of how data - often reflecting existing social biases - can reinforce or challenge dominant social structures and safety, and how such technologies shape public perceptions and knowledge production.

The research should also explore the risks these technologies pose to democratic integrity, particularly through the manipulation of public opinion, electoral processes, and governance systems. Deepfakes and AI-generated misinformation and disinformation can distort facts, spread false narratives, and undermine public trust. Addressing these concerns requires a comprehensive understanding of how AI may be (mis)used to shape political campaigns, media narratives, public engagement, and the spread and dissemination of (gendered) disinformation. Proposals are encouraged to examine how AI-generated content across media, including entertainment media, influence public opinion, social narratives, gender stereotypes and norms, and civic engagement.

Furthermore, proposals should look into how cyberviolence, including online harassment, cyberbullying, threats, and gender-based violence, is exacerbated by sharing manipulated content like deepfakes, deep nudes and AI-driven sextortion on online platforms through manipulated content like deepfakes, deep nudes and AI-driven sextortion. Research should identify how AI may be used to amplify and upscale harm, what the nature of the AI-powered output is, and which groups are disproportionately affected by it, looking particularly at women and minorities, and explore interventions to prevent and mitigate these risks. This includes analysing not only the unintended reproduction of cyberviolence through biased outputs, but also the ways in which AI-powered platforms may be misused by users to generate and/or spread harmful, discriminatory or violent content. A comprehensive assessment of unregulated AI-induced risks of sexual exploitation, violence, and gender-based harm is largely missing for effective regulation, oversight, and prosecution. A multidisciplinary review is needed to evaluate AI-driven risks exposing children, young people, women, older persons and LGBTIQ people to such violence online and offline.

Proposals should research on policy and concrete practices that can effectively address the challenges posed by AI technologies, taking into consideration the EU Regulation on artificial intelligence and subsequent guidance being developed to support its implementation. Proposals should identify best practices and regulatory measures to ensure the ethical deployment of AI and AI literacy while safeguarding equality and democratic integrity. A key aspect of this research is recognising AI’s growing role in shaping policy and judicial decisions. While its integration can improve efficiencies, concerns about bias and fairness persist. Proposals are encouraged to explore AI’s influence on legal and policy outcomes, including unintended consequences.

Additionally, proposals should consider AI’s use and impact on young people. Although AI is not specifically designed for minors, youth are among its most active users. Biases within AI-generated or manipulated content, particularly related to sex gender, sexual orientation, ethnic and racial background, can shape young users’ perceptions, perpetuate stereotypes, affect engagement and mental and physical well-being. Research should investigate how AI systems influence these aspects, and the opportunities and risks associated, including the potential psychological effects of exposure to biased or harmful content.

A key focus should be interdisciplinary research on AI’s role in societal resilience, countering misinformation and disinformation, enhancing civic engagement, and supporting marginalised communities. Proposals should explore inclusive and innovative tools and methodologies for detecting and mitigating deepfakes, disinformation, and cyberviolence facilitated through AI, designed for broad adoption by policymakers, technology developers, media organisations, and the general public.

Effectively addressing these multifaceted challenges demands to combine data-driven analysis, drawing on expertise from a wide range of fields, including both academic disciplines (e.g., computer science, and SSH disciplines such as communication and media sciences, ethics, law, political science, sociology, psychology, and gender studies) and the applied perspectives of those involved in shaping and steering AI technologies in practice.

This research should contribute to the EU’s broader AI strategy, supporting the implementation of the Artificial Intelligence Act and aligning with the EU’s Political Guidelines for 2024-2029. This research should also contribute to the implementation of other EU legislative frameworks, such as the Directive on combating violence against women and domestic violence, that criminalises various cyberviolence offences, including malicious deepfakes, and the Digital Services Act, which addresses illegal content online, including false or manipulated information inciting hate or discrimination. It should also inform global discussions on ethical AI governance and responsible innovation.

Proposals are encouraged to identify other relevant EU-funded projects, and to explore potential collaboration opportunities with them.

The projects selected for funding are encouraged to collaborate with the JRC to seek synergies with its work on innovations in public governance 59 .

HORIZON-CL2-2027-01-DEMOCRACY-05: Development aid and democratic governance

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 60 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.EU and national policymakers and development aid agencies are better equipped to deal with the complexities and challenges of the relations between the EU and low- and middle-income countries and increase their intelligence to develop EU strategies and policies that promote a more inclusive and equitable multilateralism.

2.Organisations for development cooperation have enhanced capacity and solutions to support democratic institutions and address key global challenges, such as climate action, democracy and rule of law, human rights and gender equality.

3.Strengthened multilateral partnerships between the EU as a donor of development aid and low- and middle-income countries in the field of development cooperation.

Scope: The European Union's development aid efforts face significant challenges in promoting democracy and stability in third countries, despite substantial investments in development assistance. Many countries continue to face challenges related to democratic governance, and the relationship between aid and its impact on inequality reduction, poverty alleviation, sustainable peace and security, as well as the strengthening of democratic institutions and processes, remains unclear. The resurgence of authoritarianism and the erosion of democratic values globally pose considerable challenges to EU foreign policy, underscoring the need for more effective diplomatic, security and development cooperation frameworks and strategies.

There is a pressing need for research (including by SSH disciplines) to elucidate the complex relationships between development aid, democratic governance, equality, security, and global challenges. This includes examining the effects of development aid on democratic institutions and processes, identifying gaps in funding for democratic governance, and exploring innovative approaches to supporting democratic governance and reducing inequality. In this context, the role of other non-EU aid donors, including public, private, and philanthropic actors, must be understood. This includes examining the influence of the EU's economic and geopolitical competitors, to see why their support may be more attractive to developing countries, and how they are filling vacuums left by cuts from traditional donors, creating new socio-economic dependencies and power relations.

The scope of this research topic is broad, encompassing the interplay between development aid, security, and democratic governance, with a focus on reducing socio-economic and gender inequalities, fostering democratic resilience, and promoting inclusive governance. By investigating these dynamics, researchers can uncover new insights and strategies to align development assistance with democratic strengthening, ultimately contributing to more effective and sustainable development outcomes.

Key areas of investigation include the impact of development aid on democratic institutions, the reduction of socio-economic and gender inequalities, and the identification of funding gaps for democratic governance initiatives, as well as the consequences of declining democratic trends on the effectiveness of global development strategies and the achievement of sustainable development goals.

Proposals should also seek to identify new opportunities to enhance the EU´s soft power and geopolitical influence across the Humanitarian-Development-Peace nexus, including through the development of dedicated diplomacies (e.g., climate diplomacy, water diplomacy, science diplomacy, etc.). The actions should strive to include development aid civil society organisations in the activities.

Proposals should use a gender-sensitive and intersectional approach in their research.

Proposals are encouraged to identify other relevant EU-funded projects related to EU democracy support, civil society engagement, and international cooperation on sustainable peace and democratic governance, and to explore potential collaboration opportunities with them.

Proposals may also incorporate participatory research approaches to enhance inclusivity and stakeholder engagement.

The geographical scope of this research includes the EU Enlargement, Neighbourhood 61 and low- and lower middle-income countries 62 , with a focus on the relationship of these with the EU. Therefore, international cooperation is strongly encouraged.

HORIZON-CL2-2027-01-DEMOCRACY-06: Identifying user-focused solutions to support news media freedom

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 63 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Key data gaps affecting the news media sectors at European level are addressed and all relevant stakeholders dispose of an updated and comprehensive knowledge base.

2.Users’ consumption patterns of news are identified (online and offline).

3.News media organisations and journalists are equipped with better knowledge and tools to adapt to digital transformation, to reach new audiences and to ensure a more resilient public sphere, especially for news sectors that are of particular relevance for democracy.

Scope: Free and independent news media are key tenets of our democracies as they keep citizens informed, facilitate civic engagement across all democratic processes, and keep under scrutiny those in power. At present, journalistic newsrooms are under severe economic pressure and they face increasing forms of political influence and threats against media pluralism and independence. Social media forces them to compete for citizens’ attention with other forms of infotainment, which sometimes entail unverified opinions and low-quality or malicious sources. This is particularly affecting forms of journalism relying on original content, which takes more time and resources to produce (e.g. local media, investigative journalism, public interest news, journalistic magazines, etc.). There is evidence of market failures affecting these sectors, with phenomena such as emerging news deserts, limited coverage of certain regions and/or societal groups and newsrooms closing. As a result, certain societal groups are underserved in the media landscape, so the proposed research will benefit from adopting an intersectional approach.

There are still important quantitative and qualitative data gaps at European level that can help the news media sectors address these concerns, including accurate diagnoses of the challenges and opportunities for the news sectors. The Commission’s 2023 European Media Industry Outlook 64 signalled that “the future competitiveness of this sector will depend on its capacity to invest and innovate, as well as to manage and monetise content and data”. Applicants are invited to contribute to enhancing innovation across the news media sectors, in particular by addressing data gaps, researching inspirational examples of scalable models and testing industrial models that can advance financial independence as well as editorial independence. This should include areas and aspects such as:

a) providing comparable European consumer data, market data and models to analyse audience behaviour (including audience measurement tools) across societal groups and across Europe, so as to help news media improve their relevance, editorial quality, distribution channels and business models (including emerging formats, mediums, and technologies such as AI and XR);

b) identification of market failures in news sectors of specific relevance to democracy, such as local media and investigative journalism, mapping of priority regions and/or themes, identification and analysis of business models that can address them;

c) development, prototyping and testing of small-scale innovative user-centric business models that foster the involvement of citizens in high quality information production, monetisation, distribution and consumption (including community-based, local and accessible solutions, either physical or online);

d) mapping and development of audience measurement systems, concrete suggestions to increase interoperability of tools and systems around common standards, and proposals for metadata taxonomies, to federate the news sectors and improve their negotiation power vis-à-vis tech and advertising companies.

e) sharing of conclusions and concrete, hands-on action plans and practices for the industry and policy makers, through regular consultation, interactive sessions, active communication, etc.

Consortia should:

1.bring together academia (including from SSH disciplines), civil society organisations and multiple news sectors representatives (including influencers and other content creators);

2.where applicable, leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud (EOSC), as well as data from relevant Data Spaces;

3.ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable);

4.seek collaboration whenever possible with relevant projects selected under previous EU-funded calls, such as the Horizon 2020 call topic TRANSFORMATIONS-10-2020 – “Evolving European media landscapes and Europeanisation” or the Horizon Europe one HORIZON-CL2-2022-DEMOCRACY-01-06 – “Media for democracy – democratic media”.

Clustering and cooperation among the selected projects under this topic and other relevant projects are strongly encouraged.

HORIZON-CL2-2027-01-DEMOCRACY-07: The role of private companies in democracy

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 65 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.EU and national policymakers have a better understanding of corporate influence on democratic processes and outcomes, including activities through service providers in the EU internal market, enabling them to develop strategies to mitigate negative effects and promote a more just and inclusive society.

2.EU and national policymakers have access to evidence-based recommendations and develop more effective policies and regulations for promoting responsible corporate behaviour, rules on integrity and transparency, preventing corruption and protecting democratic values.

3.Civil society organizations and citizens have a greater understanding of the complex relationships between private companies and democratic governance, enabling them to hold corporations and policymakers accountable for their actions.

Scope: The relationship between private companies 66 and democratic governance is becoming increasingly complex and contentious. As corporate interests continue to grow in influence, this raises concerns about the potential risks and benefits of private sector involvement, particularly in policymaking on contentious topics such as climate change adaptation, environmental protection, data protection, privacy, civil rights, and the rights of minorities. Thus, there is a pressing need to investigate the impact of private sector involvement on democratic processes and outcomes, as well as its long-term effects on political inequalities and shifts in power dynamics.

Large corporations and lobbying groups can inform policymaking with valuable evidence and expertise, but also potentially exert undue influence that may compromise the public interest. The implications of corporate power for democratic values, human rights, and the public good are far-reaching and require careful examination.

Moreover, external private actors, such as foreign investors and multinational companies, together with influence activities within the EU internal market through service providers (for instance lobbying or political advertising) can shape democratic processes and outcomes, and, if not conducted responsibly, risk undermining the integrity of democratic debate.

To address these challenges, research is needed (including by SSH disciplines) to explore the complex relationships between private companies, lobbying groups and democratic processes, to develop tools to assess democratic impact of corporate practices, and to identify strategies to promote responsible corporate behaviour, to uphold transparency and democratic accountability of business practices and to ensure that private companies serve the needs of democracy and the public good.

Proposals should investigate the influence of large corporations, business lobbying groups, and external actors on democratic processes, exploring the implications of corporate power on democratic values, diversity, equality (including age equality), inclusion, human rights, and the public interest. This examination should also extend to the impact of private companies on multilateral decision-making, including at the EU level, and analyse how corporate interests shape decision-making processes at the transnational level.

Particular attention should be given to the role of corporate lobbying, public-private partnerships, the role of corruption, perceived corruption, and undue influence originating from the private sector in undermining democratic governance and the public interest. This includes examining the potential for corrupt practices to emerge, such as bribery, revolving doors, and other forms of undue influence, which can erode trust in institutions and perpetuate inequalities. Furthermore, it is essential to investigate direct interferences by corporations that go beyond legitimate ways of involvement in public sector decision-making. These interferences can take many forms, including artificially spreading or amplifying disinformation in order to, influence public opinions, and steering behaviours, contributing to the normalization of extremist or polarizing actors and discourses, which can have far-reaching consequences.

Proposals are encouraged to critically examine the structural power of capital in shaping policy agendas and public discourse, and to consider how this power contrasts with that of labour and civil society. Proposals could encourage structured and sustained dialogue among business actors, citizens, regulators, and watchdog organizations, with the aim of developing inclusive and accountable governance frameworks that reflect diverse interests and promote transparency.

Proposals are encouraged to investigate the influence of private companies on democratic governance, such as – but not limited to – the potential risks and benefits of private sector involvement in sortition-based citizens' panels and other forms of participatory and deliberative democracy processes.

Proposals should use a gender-sensitive and intersectional approach in their research to analyse how the actions of private companies in a democracy impact individuals’ rights differently based on their identities.

Proposals are encouraged to identify other relevant EU-funded projects exploring the role of private companies in democracy and consider exploring potential collaboration opportunities with them 67 .

HORIZON-CL2-2027-01-DEMOCRACY-08: Global Human Rights and EU values

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.50 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 68 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.EU and national policymakers promote and protect human rights and gender equality globally by developing and implementing effective mechanisms for investigating and prosecuting international crimes, and cooperation frameworks with third countries to ensure humanitarian assistance, security, and respect for international law.

2.Organisations in the EU Enlargement, Neighbourhood 69 and low- and lower middle-income countries empower groups in a vulnerable situation and excluded or marginalized individuals, including, by promoting and protecting human rights and gender equality, providing essential services, and advocating for policy changes that advance equality and social justice, through enhanced capacity, awareness, strengthened partnerships, and effective reporting of human rights abuses.

3.EU and national policymakers integrate human rights considerations into trade policies and practices, ensuring that trade agreements, supply chains, and labour standards promote human dignity, equality, fairness and well-being, and prevent human rights abuses.

Scope: The promotion of human rights and gender and age equality is a pressing concern for the European Union in today's multipolar world, where vulnerable groups in a vulnerable situation and excluded or marginalized individuals, including ethnic and religious minorities, people with disabilities, migrants, as well as women, and LGBTIQ people, face persecution, discrimination, and violence. The EU's response to these issues is influenced also by the complexities of global governance, trade, human rights and rule of law, and geopolitical interests.

The EU's values and human rights are being tested in a global context, where trade policies, supply chains, and labour rights are increasingly intertwined. The impact of sanctions and trade, conditionality, and other measures on human rights is unclear, and the role of national and international courts and international organisations in promoting accountability is uncertain and increasingly contested.

Moreover, the EU's external actions and Member States’ foreign policies have internal consequences, for instance undermining their democratic reputation and values if they are perceived as inconsistent or hypocritical, or producing negative impacts on European enterprises in terms of access to markets or to critical raw materials. For groups, such as refugees, women, LGBTIQ people, elderly persons, and indigenous peoples, who are already subject to various types of exclusion and discrimination and who might be further disenfranchised by the EU's foreign policy, this is particularly problematic.

There is a need for research (including by SSH disciplines) to better understand these complex relationships and to identify innovative approaches to promoting and protecting human rights and gender equality. This includes examining the impact of trade policies and investments policies on human rights (including Global Gateway infrastructure investment strategy), and on the perception of the EU as a values-based actor, developing effective diplomatic strategies and cooperation frameworks, and investigating the role of national courts and international organisations in promoting accountability.

Proposals may also incorporate participatory research approaches to enhance inclusivity and stakeholder engagement.

Proposals are encouraged to identify other relevant EU-funded projects related to EU democracy support, civil society engagement, and international cooperation on sustainable peace and democratic governance, and to explore potential collaboration opportunities with them.

The geographical scope of this research should include the EU Neighbourhood 70 and low- and lower middle-income countries 71 , with a focus on the Western Balkan and the accession countries. International cooperation is strongly encouraged.

HORIZON-CL2-2027-02-DEMOCRACY-09-two-stage: Open topic on reinvigorating and shielding European democracy

Call: Culture, Creativity and Inclusive Society - 2027 - Two-stage

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 2.00 and 3.70 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 22.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

In order to achieve the expected outcomes, consortia must include, as beneficiaries or affiliated entities, (i) at least one relevant public body with a policy-making role; and (ii) at least one relevant civil society organisation.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 72 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1. EU institutions and national decision-makers, civil society organisations and other societal actors and citizens at large are better equipped, with new data, knowledge and methods, to confront threats and challenges of democracies as well as to enhance their inclusiveness and participatory elan.

2.Strengthened citizens’ long-lasting engagement in the democratic life, including but going beyond electoral processes, and increased trust in democratic institutions.

Scope: The Political Guidelines for 2024-2029 of the European Commission 73 announced a new European Democracy Shield. Building on the European Democracy Action Plan 74 and the Defence of Democracy Package 75 , this initiative aims to safeguard, strengthen and promote democracy in the EU and to reinforce public trust. The Democracy Shield will aim to reinforce citizens’ participation and engagement in the democratic life, promote free and fair elections and support free and independent media. It will also address the increasing threats to democratic systems, institutions and processes within the EU, often driven by various hostile actors aiming to undermine citizens’ trust in democracy and its institutions. In addition, the Commission is also preparing a Civil Society Strategy and has also announced an updated strategy on LGBTIQ equality, a new anti-racism strategy, a new gender equality strategy, and a roadmap for women’s rights 76 It also continues implementing the Strategy for the rights of persons with disabilities 2021-2030 77 , in line with the United Nations Convention on the rights of persons with disabilities, which the EU and its Member States are parties to 78 .

Ensuring full, equal and meaningful political participation for everyone, regardless of sex, gender, racial or ethnic origin, religion or belief, disability, socioeconomic status, employment or age, fosters more stable and resilient democracies. Decision-making processes that incorporate a wider range of perspectives and experiences leads to policies that are more comprehensive and attuned to the needs of all citizens.

Under this open topic, proposals should address existing, upcoming or unforeseen challenges and/or creative or disruptive solutions for protecting European democracy, enhancing citizens’ trust and political participation, expanding inclusiveness and fairness of democratic institutions and practices and supporting and protecting civil society. Proposals are encouraged to investigate the opportunities offered by digital and other new technological solutions, notably from the civic tech sector. Proposals should address unmet research needs, complementing previous Horizon Europe calls.

In that sense, proposals should consider, build on – if appropriate – while not duplicating, previous research, including but not limited to, SSH disciplines and/or research by other Horizon Europe projects, in particular in the context of this destination. Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact.

Given the multifaceted character of the challenges confronted by democracies, applicants should ensure effective interdisciplinary collaborations by building consortia with the participation of all relevant disciplines, depending of course on the nature of the selected democratic challenge and research angle.

Applicants are encouraged to adopt innovative approaches, including also by considering alternative and complementary models for democratic participation and engagement, facilitating the development and potential uptake of solutions. To ensure the active involvement of and timely feedback from relevant democracy practitioners and policymakers, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term contributions to the expected outcomes, performed by the democracy practitioners and policy-makers. Proposals should directly engage citizens, as well as civil society organisations, to enable broader public debate and explore uptake of democratic innovations and better anticipate potential risks.

Proposals are encouraged to collaborate with the JRC Competence Centre on Participatory and Deliberative Democracy, particularly with respect to demonstrating how structured opportunities for citizen participation strengthen inclusiveness and fairness of democratic institutions and practices, and foster evolution in democratic public spaces.

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud (EOSC), as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

Destination Innovative Research on European Cultural Heritage and Cultural and Creative Industries

Europe’s rich cultural heritage and strong creative industries not only reflect our past but also shape our future. It is by building on this foundation and developing our strengths that we can face the great challenges of our time with confidence and shape a desirable common future. Europe's cultural heritage originates from the interaction between people and places through time and is constantly evolving 79 . Every citizen has a right to engage with the cultural heritage of their choice, while respecting the rights and freedoms of others, as an aspect of the right to participate freely in cultural life 80 .

Europe’s diverse tangible and intangible cultural heritage and dynamic cultural and creative industries (CCIs) are strategic assets. They enrich our lives, foster social cohesion and societal resilience, and contribute to a sense of belonging. They underpin a growing economy that generates more employment than the automotive industry and a similar trade balance as food, drinks and tobacco combined. Many of Europe’s multinational companies build their international success on European heritage and creativity. At the same time, the sector is nurturing large numbers of dynamic small, medium (SMEs) and micro enterprises, creating employment not the least for young people, while deploying their creativity not only to generate income but also to contribute to social and cultural sustainability, wellbeing and to projecting European values at home and abroad. The cultural and creative industries are engines of innovation not only in themselves, but across the entire economy, thus contributing strongly to Europe’s overall competitiveness and future prosperity.

This destination adopts a people-centred perspective and places cultural heritage and the cultural and creative industries at the very heart of the European economy, its competitiveness and sustainability. R&I activities under this destination will be aligned with the main principles and objectives of the Culture Compass for Europe and support objectives such as circular and just fashion and textiles value-chains, social cohesion and resilience through arts, design and cultural practices and creative entrepreneurial ecosystems for regional development. R&I activities under this destination will support and strengthen European cultural heritage and cultural and creative industries essentially along the following lines:

Europe’s sustainable prosperity and competitiveness: To secure Europe’s future prosperity and competitiveness, it is necessary to unlock the innovative power of our cultural heritage and CCIs. The CCIs contribute strongly to drive innovation not only in themselves but also in other industries and economic sectors, shape new technologies and can contribute to user-driven innovation, open innovation and cross-sectoral innovation, in addition to their wider societal contributions such as to cultural wealth, social cohesion and resilience.

R&I actions under this area will focus on boosting the innovation-driving role of the CCIs, on creative startups, on the impact of artificial intelligence technologies on creativity and CCIs, while ensuring that new technologies are fairly deployed, along with the contributions of artistic intelligence and soft skills, boosting a circular economy and global partnerships in cultural policies and CCIs, among other things.

Supporting people, strengthening our societies and our social model: Cultural heritage, the arts and the CCIs have a crucial role to play for resilient and socially sustainable societies, shaping and strengthening the values that hold us together and give meaning and a sense of belonging.

R&I actions under this area will focus on boosting the role of culture, the arts and creative industries in contributing to well-being, to the social economy and in general the societal impact of cultural heritage. R&I actions will explore and strengthen the role of culture, heritage and CCIs in shaping the technologies of the future and focus on safeguarding intangible heritage and linguistic diversity, on sustainable cultural tourism and on countering illicit trafficking of cultural goods, among others.

Some actions funded under this Destination will need access to and/or generate data. Where appropriate, actions should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud or included in the European Strategy Forum on Research Infrastructures (ESFRI) and the ESFRI roadmap, as well as data from relevant European Data Spaces. In particular, projects that produce data or digital tools of potential interest to cultural heritage institutions or researchers should, as appropriate, establish links to and/or consider integrating their results in the European Collaborative Cloud for Cultural Heritage (ECCCH) 81 .Particular efforts should be made to ensure that the data produced in the context of actions under this Destination is FAIR (Findable, Accessible, Interoperable and Re-usable).

The innovation ecosystems created and nurtured by the Knowledge and Innovation Communities (KICs) of the European Institute of Innovation and Technology (EIT), in particular the KIC “EIT Culture and Creativity”, may contribute to actions under this destination, and may as appropriate be considered by applicants. Furthermore, applicants are invited to consult funding opportunities in other parts of the Horizon Europe Work Programme, including for instance the funding opportunities for companies, high potential start-ups, entrepreneurs and innovative researchers offered under the European Innovation Council.

R&I actions under this Destination will help ensure Europe’s sustainable prosperity and competitiveness, support people, strengthening our societies and our social model, contribute to protecting our democracy, upholding our values and boosting a global Europe, leveraging our power and partnerships. They will contribute to reaching the UN Sustainable Development Goals and to building a stronger, more participatory and crisis-resilient society and economy. They will support the realisation of the full potential of cultural heritage, arts and cultural and creative industries as drivers of sustainable innovation and a European sense of belonging.

To maximise the impacts of R&I under this Destination in line with EU priorities, international cooperation is encouraged whenever relevant in the proposed topics.

Expected impact:

Proposals for topics under this Destination should set out a credible pathway to contributing to the following expected impact of the Horizon Europe Strategic Plan:

1.The full potential of cultural heritage, arts and cultural and creative industries and sectors as drivers of both sustainable innovation and a European sense of belonging is realised through a continuous engagement with society, citizens and economic sectors.

EUROPE’S SUSTAINABLE PROSPERITY AND COMPETITIVENESS

Proposals are invited against the following topic(s):

HORIZON-CL2-2026-01-HERITAGE-01: “Artistic intelligence” : harnessing the power of the arts to address complex challenges, enhance soft skills and boost innovation and competitiveness

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.50 and 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 15.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 82 .

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000.

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Proposals should contribute to the first two expected outcomes, and either the one listed under Focus 1, or the one listed under Focus 2.

1.The potential of art-science and/or technology collaborations to address societal challenges and drive innovation is better understood. Guidance, toolkits, and actionable methodologies are developed to promote these collaborations, providing policymakers, professionals, and training organisations with clarity on intervention scope, applicability across various fields, and evaluation methods, metrics, or tools.

2.New and existing national, European or international networks for art-science-technology collaborations are established or strengthened, expanding opportunities for artists to engage with science and technology.

Focus 1

Approaches, methodologies and model interventions for integrating arts and creative practices to enhance soft skills across public and private sectors are developed, tested and disseminated.

Focus 2

The effectiveness of critical artists’ engagement in interdisciplinary teams is demonstrated alongside the assessment of the viability of research-intensive emerging technologies through at least three low technology readiness level (TRL) pilot demonstrators.

Scope: Artistic research fosters inter-, multi-, and trans-disciplinary thinking, inspiring innovative problem-solving and offering new avenues for innovation across policy areas, akin to scientific research. EU initiatives such as SciArt and S+T+ARTS 83 show that art-science-technology collaborations enhance scientific and technological progress. Art acts as a catalyst for innovation, developing creative solutions to complex challenges and brings fresh perspectives to the scientific community. Artistic research is increasingly fostering mutual fertilization between the arts and academia. Collaboration with artists leads academics to adopt experimental practices, while artists increasingly engage with theoretical aspects of their practice. Closer collaboration between artists and companies in emerging technologies ensures that technological developments are guided by diverse, human-centred perspectives. Artistic research offers cross-disciplinary insights that challenge conventional thinking, spark innovation beyond technical efficiency, and address societal challenges holistically. Furthermore, artistic intelligence 84 makes complex concepts accessible and engages audiences emotionally and culturally. Artistic expression facilitates the adoption of innovative concepts and practices and catalyses social innovation, supporting sustainable and inclusive societal transformations and the cultural uptake of socio-scientific issues. Now is the time to consolidate understanding of the transformative potential of art-science-technology collaborations, distil it for application across policy areas and levels, and develop methods to evaluate their impact both quantitatively and qualitatively. Projects are expected to:

1.Gather evidence on art-science-technology collaborations for addressing societal challenges and spurring innovation in science and technology.

2.Collect case studies, produce and disseminate guidance, toolkits, and methodologies supporting policymakers in promoting these collaborations and strategies for cross-disciplinary innovation. Mechanisms, span of possible interventions, applicability to diverse fields and contexts will be clarified and exemplified.

3.Develop concrete use cases, such as (but not limited to): artists supporting ethical, inclusive, human-centred AI; addressing societal challenges and complex transformations through art-science-technology collaboration, advancing emotional storytelling, experiential art and public engagement through AI and real-time data; public sector roles in the art-science-technology uptake; role of artists in catalysing innovation in policymaking; participatory art-science-technology initiatives and citizen science.

4.Develop and test qualitative and quantitative methodologies and key performance indicators for evaluating such interventions, assessing their impacts, measuring their medium to long-term benefits and identifying what constitutes success.

5.Increase opportunities for artists to engage in art-science-technology collaborations, through network establishment or consolidation, interdisciplinary initiatives or other methods.

Project consortia should include artists and creatives/representatives of creative industries. Through leveraging creativity, projects should boost EU productivity and competitiveness while improving artists and creative professionals' employment conditions and preserving the autonomy and freedom essential to artistic practice and democratic society.

Financial support to third parties of up to EUR 60.000 in the form of grants may be considered, with the aim of actively engaging artists and creative professionals, for example through residencies, to facilitate development of solutions and innovative experimentations.

In addition to the main focus area, proposals should choose between the following two focuses:

Focus 1. Enhancing soft skills through creativity and the arts

Policies and strategies for introducing creative thinking and cross- and transdisciplinary methods in education, research and the broader public and private sectors are needed. In the workforce, engaging with creative practices and the arts enhances soft skills -such as creativity, critical thinking, problem-solving, emotional intelligence - crucial for productivity and competitiveness in an increasingly automated world 85  and to meet the demands of a changing market. Supporting research and innovation in this area will help individuals and institutions develop the skills and mindsets needed to thrive and increase creativity, productivity and well-being, including mental health, in a complex, interconnected society. Projects are expected to develop, experiment, and disseminate frameworks for using the arts and creative practices to strengthen soft skills in various public and private sectors, including education and lifelong learning, public administration and corporate environments, and showcase best practices. Proposals may choose their own areas of application.

Focus 2. Pilots on emerging technologies

Proposals should develop at least 3 small scale pilots on emerging technologies in interdisciplinary settings involving artists, to assess, demonstrate and streamline research-intensive technologies. Candidate technologies could include, among others, immersive arts, grid sensing networks, multisensuality, ubiquitous XR, spatial computing, VLM/LLM and historical data, crowd digitization or virtual reality. Pilots should demonstrate the effectiveness of artists’ engagement.

Proposals should clearly indicate the focus they have selected.

Proposals should consider the involvement of the European Commission's Joint Research Centre (JRC) based on its experience, in particular with the SciArt programme, and with respect to the value it could bring in providing an effective interface between research activities and policymaking.

HORIZON-CL2-2026-01-HERITAGE-02: Boosting creative startups for disruptive innovation

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 6.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Innovation Actions

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio, grants will be awarded to applications not only in order of ranking but at least also to those that are the highest ranked within each of the two options provided in the scope (Option a and Option b), provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 86 .

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000.

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Deepened knowledge of specific factors favouring the growth of creative startups 87 , in particular those with potential for disruptive innovation 88 and/or cross-sectorial innovation impacts, is made available and promoted to policymakers, investors, funding- and enterprise support bodies.

2.Effective methods to favour the growth of creative startups, in particular those with potential for disruptive innovation and/or cross-sectorial innovation impacts, are developed, tested and put in practice by industry, investors, funding- and enterprise support bodies, and relevant decision makers.

3.Examples of creative startups scaling up and/or engaging in disruptive innovation are made available, with a view to increase the visibility and recognition of the innovative power of Europe’s creative startups.

In addition, proposals should contribute to at least one of the following expected outcomes, depending on the option chosen (a or b below):

1.The effectiveness of the methods developed is demonstrated by at least one creative startup supported via the action becoming a scaleup 89 in a Member State or an Associated Country.

2.The effectiveness of the methods developed is demonstrated by at least one creative startup or scaleup supported via the action succeeding in bringing a disruptive innovation to the market.

Scope: The cultural and creative industries (CCIs) count a high rate of startups. Data indicate that CCIs are among the early adopters of new technologies, especially in the digital realm. For instance, the European Monitor of Industrial Ecosystems (2024) 90 notes that artificial intelligence-based technology startups were most common among the CCIs and in the health sector. Furthermore, creative startups drive innovation through crossovers with other sectors. They can be a motor of growth in local economies, unlocking opportunities, investment, jobs and higher productivity. That is why a host of initiatives like creative clusters, innovation hubs, smart specialisation strategies, innovation ecosystems, etc. foster the emergence of creative startups. Also at EU level, there are a number of initiatives to support startups and/or cultural and creative industries 91 , and there is a clearly stated ambition to make EU the preferred choice for startups and scaleups, as expressed in the EU Startup and Scaleup Strategy 92 .

However, in order to better support European creative startups to grow into scaleups and to multiply their potential as high-impact disruptive innovators, in line with the EU Startup and Scaleup Strategy, additional measures are needed.

The challenge is to deepen the knowledge of the most important factors that favour the scaling up of creative startups in Europe and unleashing their potential for disruptive innovation, with a particular focus on those factors that distinguish them from startups in other sectors.

Proposals are expected to focus either on:

Option a: Boosting the growth of creative startups into scaleups.

Option b: Boosting creative startups or scaleups with a potential for disruptive innovation.

Proposals should clearly indicate the option they have selected.

Approaches should be devised that boost the growth of creative startups in Europe and/or encourage engaging in disruptive innovation. Approaches developed may build on existing methods, such as shared technological resources/platforms to lower investments needs, credible assessments of technologies, IPR or of creative companies to increase investor readiness, matchmaking platforms, etc. However, the approaches to be developed under this action should be innovative and go beyond the existing ones. They should be effective and feasible across Europe under the current legal framework.

In order to validate and refine the proposed approaches, projects should carry out at least 3 pilot trials in different settings under real-world like conditions. These should involve piloting the scaling-up of a creative startup or positioning a creative startup/scaleup for bringing disruptive innovation to the market, according to the option chosen (a or b above). Financial support to third parties may be considered, with the aim of engaging diverse innovative creative startups, facilitating the uptake of solutions devised by the projects, experimenting with innovative approaches, or engaging other funders in co-financing.

To the extent appropriate, projects should build on and take advantage of previous research, networks, policy initiatives and infrastructure at European and national levels. This may include building on results of or structures developed by relevant R&I projects funded under Horizon Europe or other EU funding programmes that focus on boosting the innovation potential of CCIs, the EIT Knowledge and Innovation Community ‘EIT Culture and Creativity’ 93 , or other relevant projects and networks. Such existing networks and infrastructures may also include business incubators or accelerators, venture capital networks 94 , etc.

To the extent appropriate, the Commission expects projects funded under this topic to establish coordination mechanisms in order to achieve the strongest possible common impact. One such area of cooperation could be communication and dissemination efforts.

The Commission estimates that a project duration of at least 4 years is appropriate, in order to be able to achieve the expected outcomes.

HORIZON-CL2-2026-01-HERITAGE-03: AI integration in CCSI work practice: catalysing innovation and competitiveness

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.00 and 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 15.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 95 .

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000.

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Insights, recommendations, strategies, guidelines, methods and tools supporting full AI integration in CCSI practices become available to CCSI, policymakers, and stakeholders.

2.Scenarios for co-created solutions tailored to CCSI needs, utilizing quality data and federated data sources, along with digital infrastructures, and inclusive cooperation processes, become available.

3.Generally made available AI-powered and ethically designed solutions, tools and services in several CCSI areas benefit creators, cultural professionals, and society, including persons with disabilities and other specific needs, fostering innovative creative expressions and improving creative business models while preserving and enhancing cultural diversity, and inclusion.

4.By mastering ethical and inclusive AI, CCSI are empowered drivers of culture, innovation, competitiveness and societal wellbeing.

Scope: AI technologies are transformative, providing unprecedented opportunities for human creativity, experimentations and co-creations. AI profoundly impacts cultural and creative sectors and industries, changing practices, facilitating new ways of working and making innovative services and products possible. Artists, industry players, and cultural organisations increasingly use AI, for assistance in content creation, production, and management, to predict trends, personalise market content, engage audiences, enhance cultural heritage preservation and accessibility, and many more purposes.

Cultural and creative sectors and industries (CCSI) 96 need to fully harness AI's potential to maintain relevance, expand their impact and value, increase competitiveness, and keep their vibrant, inclusive nature. Embracing and co-creating ethical AI solutions tailored to CCSI needs will, among other benefits, enable the automation of low-creativity tasks, allowing to increase focus on high-value activities that enhance creativity and productivity, thus unlocking unprecedented possibilities. Production times and costs can be reduced, market reach expanded, preservation, interpretation and inclusive access to cultural heritage enhanced, and new job categories could emerge.

Although several initiatives are on the ground, a comprehensive understanding of enabling frameworks and factors and of what is still lacking in terms of data, standards, infrastructures, computing power, tools, knowledge and capacity for the CCSI to fully embrace the opportunities opened by AI is essential for effectively integrating AI technologies into CCSI practices and workflows. Proposals should assess the current level of AI readiness in the CCSI, investigate the specific barriers to AI adoption in the sectors, and highlight areas where AI can offer the most benefits. In continuous engagement with the sectors, based on the analysis of current practices and through concrete use cases, proposals should produce strategic guidance to extensively and seamlessly integrate AI into CCSI operations, enhancing efficiencies, averting risks, and facilitating cross-sector collaboration. Based on this analysis, they should develop a set of tailored tools designed to address the specific gaps and leverage the opportunities uncovered during the assessment. These tools should be strategically aligned with the sector's needs, ensuring they provide targeted solutions to enhance AI adoption and maximize its potential benefits. They should be scalable, affordable for smaller, less-resourced CCSI actors and accompanied by related documentation and training materials and documentation.

Proposals should address one of the following two options, and are allowed to address both:

1.Develop scalable pilots for innovative AI-enabled products and services across diverse segments of sectoral value chains, in cooperation with CCSI. These pilots are expected to address identified gaps in CCSI operations and prioritise solutions that catalyse innovation in sectors whose business models are not yet taking full advantage of AI. Applicants should have flexibility to select their preferred application areas.

2.Design and pilot innovative, inclusive, ethically driven, transparent AI solutions to foster cultural and linguistic diversity, and enhance accessibility, with a focus on engaging individuals in vulnerable situations, particularly youth, older people, persons with disabilities and individuals with special needs. Applicants should have the flexibility to select their preferred application areas.

Pilots should aim at leveraging AI for facilitating new revenue streams for the CCSI, as well as sustainable business models, and will highlight marketable solutions.

Financial support to third parties may be foreseen, with the aim of engaging entities external to the consortium in the development of pilots.

Consortia should include representatives of the cultural and creative sectors and industries and technology developers.

Proposals should consider relevant policy initiatives, such as the AI Continent Action Plan 97 , and build upon existing research and innovation outcomes, particularly insights and resources from Horizon Europe-funded projects focused on digital transformation, innovation, or competitiveness in the CCSI, and science-technology-art collaboration, and should liaise with the EIT KIC Culture and Creativity. Whenever relevant, they might make use of existing facilities and platforms such as the European High-Performance-Computing network, the European Collaborative Cloud for Cultural Heritage (ECCCH), the Common European Data Space for Cultural Heritage, ALT EDIC and other data spaces, European Digital Innovation Hubs, AI Factories, and relevant research infrastructures.

HORIZON-CL2-2026-01-HERITAGE-04: Towards a fair and transparent market for cultural and creative content in the era of generative AI

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 98 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.An in-depth analysis of the socio-economic dimensions and impacts of generative AI on the cultural and creative sectors and related societal implications. Particular attention should be paid to rights and remuneration of creators, diversity of cultural expression, audience perception, consumption patterns, market dynamics, value chains, royalty allocation and the effectiveness of copyright infrastructure.

2.Scenarios, value chains, standards and robust, agile solutions to ensure transparency and trust in the generative AI supply chain are developed, aiming for a fair and transparent market for cultural and creative content. This includes: systems for content provenance detection of AI-generated and manipulated creative content; tools and infrastructure that reinforce rights management, creators’ consent, control, and fair compensation for the use of their works in AI training and generation; measures supporting the findability and discoverability of trustworthy cultural and creative content; mechanisms for the long-term preservation and stewardship of AI-generated creative works.

3.Adaptive policy frameworks, recommendations, and solutions that embed cultural and ethical considerations in AI development for/with CCSI. These should ensure a fair and ethical market for cultural and creative content, products and services. Concrete solutions to address identified challenges and ensure equitable and sustainable creative economies, including agile mechanisms to ensure equitable value distribution, are proposed.

4.A systemic innovation framework for sustainable CCSI is developed and validated. It enables agile experimentation, design, and testing of future-proof business models, that support compliance with ethical standards, legal requirements, and resource-efficient practices adaptable to market and technological changes.

Scope: The impact of generative AI on the CCSI and society is complex and multifaceted 99 . While it offers new possibilities, it also raises concerns, particularly regarding copyright, revenue models, employment patterns, and audience engagement. Understanding these socio-economic impacts, including how AI shifts the way the arts and culture are understood, created, practiced, and learnt, is crucial.

Generative AI can produce outputs potentially competing with human-created content. AI can also facilitate the manipulation of creative works, potentially infringing copyright or misleading users. Increasing transparency of AI generated or manipulated content may help to distinguish between human-created and machine-generated content and inform new practices for content dissemination and consumption.

Challenges related to the availability of quality data for AI applications and to the accuracy and reliability of cultural content should be investigated and addressed. In particular, the development of Generative AI technologies requires access to vast amounts of content that is often still protected by copyright. One of the challenges in this context is linked to the difficulty to identify copyrighted works, rightsholders and information on how their works may be used. The purpose of the insights gained is to inform novel practices for managing AI-generated content in cultural and creative fields, including the preservation of valuable outputs, such as artworks created by using AI, and to inform the establishment of adequate policy and legal frameworks and infrastructures.

Proposals should primarily address the following dimensions:

1.Investigate and identify emerging trends, including through scenario analysis, and estimate the economic and social implications and impact of AI-generated outputs on the creative content market and related services, and on different actors and sectors, with a special focus on creators’ rights, earnings, allocation of royalties, as well as on diversity, inclusion, consumption and user perception of cultural products and services.

2.Examine and propose policy and legal frameworks to ensure a sustainable and innovative creative sector in the age of AI.

3.Propose standards and robust solutions to map the generative-AI supply chain, identify, trace and find trusted content, and ensure authenticity; tools for strengthening consent, control, rights management and compensation for the use of artistic and creative data in AI; suggest other measures to ensure a fair and transparent market for cultural and creative content, including solutions to increase the discoverability of trustworthy cultural and creative content, including copyright protected content that could be used for the AI training.

4.Investigate new, efficient ways to redefine value creation and transformed business models. This includes looking at uncovering opportunities that support human creation, and increase profitability, while providing frameworks for the distribution of AI-generated and/or assisted creative content, and measures for long term preservation of valuable works created with the use of AI.

5.Systemic and agile innovation: propose a validated framework to experiment, design, prototype and test new business models that can adapt to a rapidly evolving market, are resource efficient, and comply with ethical and regulatory frameworks.

By integrating these findings and insights, risks associated with generative AI can be mitigated and new positive prospects developed. Insights gained are expected to contribute to the EU’s global leadership in creativity and innovation.

Proposals should consider relevant policy initiatives, such as the AI Continent Action Plan and the envisaged AI dedicated strategy for the cultural and creative sectors 100 , and build upon existing research and innovation outcomes. Proposals selected under this call should collaborate and, if relevant, build upon the research developed by projects retained under call HORIZON-CL2-2025-01-HERITAGE-04.

HORIZON-CL2-2026-01-HERITAGE-05: Creative alliances: Fostering global partnerships in cultural policies and CCI innovation

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 3.75 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 15.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, of the action, the consortium must include at least three entities from at least one of the world regions identified (Africa, the Far East, South-East Asia, Latin America). Legal entities from these regions must take part in the project as beneficiaries. Due to the scope of this topic, legal entities established in these regions are exceptionally eligible for Union funding.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 101 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Deepened understanding and comprehensive evaluation of cultural policy models, creative industry ecosystems, and strategies for promoting creative industries across world regions, identifying good practices, success stories and replicable models. Innovative practices, policy approaches, shared challenges, and opportunities for cross-regional collaboration and global development of creative industries are identified.

2.International equal partnerships and collaborations are established to exchange cultural policy approaches, boost creative industries, and/or support collaborative production or co-creation, facilitating knowledge transfer and capacity building among participating actors.

3.Actionable strategies are available to policymakers, businesses, and stakeholders, for cross-regional collaborations that strengthen cultural ties, leverage creative industries, culture, and the arts as central to Global Europe, and support global culture- and creativity-driven innovation and resilience.

Scope: This topic explores how international partnerships can strengthen cultural policies and creative industries innovation, promote cross-cultural collaboration, and support sustainable development and global relations. Proposals should examine innovative approaches that benefit partners worldwide while enhancing Europe's global standing through cultural cooperation. The topic has two distinct but interconnected focuses; proposals should select one but may also consider complementarities and synergies with the other.

Focus 1: Cultural and creative industries’ innovation beyond borders

Creative industries are gaining global attention for their multifaceted impact on economies and societies, driving economic growth, job creation, opportunities for youth, women, and persons with disabilities, while generating value and fostering wellbeing across regions. By investing in digital and green transitions, adopting ethical and open AI, and leveraging cultural heritage, the EU offers a compelling paradigm for creative industries worldwide. This approach strengthens creativity within Europe and can inspire other regions developing their own cultural and creative economies, contributing to a flourishing global creative ecosystem. Creative industries support resilient, inclusive, balanced and mutually respectful partnerships that create new markets and drive innovation, advancing a global Europe. There is a growing need to explore diverse approaches to promoting cultural and creative industries, fostering knowledge exchange and mutual learning to amplify positive impacts worldwide, with Africa, the Far East, South-East Asia, Latin America being particularly promising regions for cooperation. Proposals should establish pilot projects to demonstrate the potential of cross-regional cooperation in creative industries, addressing specific regional challenges and opportunities. They may leverage the EU Global Gateway strategy to foster resilient, inclusive, and innovative global partnerships. 

Focus 2: International cultural relations for global resilience

While often used interchangeably, cultural diplomacy, international cultural relations, and soft power each reflect different layers of collaboration and competition: cultural diplomacy often advance national interests through cultural exchange, international cultural relations emphasise mutual and reciprocal engagement, and soft power highlights the subtle influence of culture and creativity in shaping global perceptions.

As traditional diplomatic channels face pressures, these approaches have become vital for enhancing mutual understanding, building trust, and fostering dialogue and cooperation across borders—even amid political disagreements. They promote societal resilience and peaceful coexistence by highlighting common values, easing tensions, and bridging divides. International cultural relations also offer opportunities to strengthen existing partnerships or forge new ones—important also for Europe’s own strategic autonomy—by leveraging shared values, cooperation mechanisms, existing networks (including the EU Global Gateway), and diverse cultural diplomacy strategies in today’s geopolitical landscape.

Proposals under this focus should establish pilot projects to test innovative forms of international cultural relations, such as initiatives fostering intercultural dialogue among communities experiencing tension or affected by conflict; collaborative artistic projects promoting mutual understanding and countering nationalism, xenophobia or conflict; cultural partnerships that avoid asymmetric power dynamics; or joint activities demonstrating how culture can strengthen societal resilience through inclusion, diversity, openness and how arts, design and cultural practices contribute to social cohesion. Africa, the Far East, South-East Asia, Latin America are regions of particular interest for this focus area as well. Proposals should clearly indicate the focus they have selected.

Projects should establish mechanisms for ongoing collaboration that leverage each region's cultural assets and industry innovations to address global and local challenges

Proposals addressing either focus may also explore ways to address unequal access to global markets and imbalances in partnerships within the creative economy, with attention to gender and other intersectional aspects shaping opportunities and participation. Research organisations, policy think-tanks, creative industries representatives, artist organisations/artists, tech communities, and cultural organisations from Europe and partner world regions are encouraged to participate.

Proposals should involve CCSI representatives from the outset to ensure their central role. Proposals need not cover all CCSI but may focus on a specific area for in-depth analysis to develop a strong knowledge base and highlight strategic directions and routes to improvement. Proposals should explore synergies with other EU programmes supporting international cultural and creative partnerships, including the European Spaces of Culture, 102 and may seek complementarities with projects funded under the topic HORIZON-CL2-2025-01-HERITAGE-07. In order to achieve the topic’s expected outcomes, international cooperation is encouraged.

SUPPORTING PEOPLE, STRENGTHENING OUR SOCIETIES AND OUR SOCIAL MODEL

HORIZON-CL2-2026-01-HERITAGE-06: Safeguarding linguistic diversity in Europe

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 5.75 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 11.50 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 103 .

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000.

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all the following expected outcomes:

1.Enhanced understanding, accompanied by documented good practices, showing what works to encourage multilingualism in society and what type of practices have led to safeguarding linguistic heritage, including lesser used, endangered and historically marginalised languages.

2.Rigorous policy-relevant evidence, strategies and policy recommendations for promoting multilingualism and safeguarding linguistic diversity are available to policy makers, and users are involved in their development, especially the younger generation. Non-linguistic benefits of language maintenance and revitalisation are well documented, communicated and understood by different stakeholders.

3.Citizens are empowered and engaged in the sustainable management of their own linguistic heritage and resources, with a focus on intergenerational dialogue and education activities, with particular attention to communities where oral transmission is the primary mode of language preservation.

4.Maps and visual presentations showing the linguistic diversity in Europe are available, including a variety of existing languages (regional and minority languages, indigenous languages, low resources languages etc.) and offering suited terminology and explanations.

Scope: Linguistic diversity is a fundamental part of Europe’s cultural heritage. When languages disappear, a whole knowledge system disappears, and cultural diversity is impoverished. Linguistic diversity plays a key role in safeguarding cultural diversity. Languages are the expression of the identity, culture and the way peoples perceive their world. Knowledge and culture are lost when languages are lost.

The EU has 24 official languages and some estimated 60 other languages spoken in particular regions or by specific groups. They are an essential part of the rich fabric of European culture. The proposals would document and map the situation of linguistic diversity in Europe, taking into consideration existing frameworks, initiatives and working terminology established by the Council of Europe and UNESCO.

The proposals should identify examples of good practice that have resulted in richer use of languages in society, thus promoting multilingualism, and would support sharing of knowledge and good practices.

Moreover, in recent decades, multilingual regions have been affected by a confluence of demographic, socio-economic, and sociocultural challenges. An aging population coupled with lower birthrates has strained these communities, leading to a decrease in the number of native speakers who can transmit their linguistic heritage to younger generations. The housing crisis affecting several of these regions, also driven by tourism, exacerbates this dilemma, as economic pressures force long-time residents to leave their ancestral homes. Migration, while enriching in diversity, often further dilutes the linguistic fabric as newcomers bring different linguistic traditions and younger generations gravitate toward globally dominant languages. The sociocultural landscape is equally challenging, with the loss of monolingual minority speakers and community life and the media environments that increasingly prioritize universal appeal and dominant languages over local authenticity. This is particularly acute for itinerant or dispersed communities, e.g. Roma communities, whose linguistic heritage is often overlooked in mainstream narratives.

The proposals should explore how these elements have changed the language situation in those areas and how the different regions have adapted to the new linguistic environment, and what are the effects on the local economy. Particular attention should be given to languages with limited institutional support to explore how better visibility and accurate representation could be achieved.

Another element changing the game for language learning and safeguarding heritage are digital technologies. The projects should address the online presence of different languages and explore how language technologies could overcome the deepening linguistic divide in the digital domain 104 , while also documenting the availability of language data. Proposals should also look at the presence of different languages in different forms of media, arts and wider forms of cultural expressions. Projects could also explore how digital platforms and AI tools can aid in language preservation, especially for endangered regional languages.

The projects should explore the non-linguistic benefits of language maintenance, regeneration and learning. They could also look at how multilingualism and maintaining and learning heritage languages affects people’s wellbeing, self-respect and health due to the comfort, lower stress and sense of security at being able to speak their first language and not have their identity challenged. The actions should propose ways to encourage and support multilingual education and intergenerational transmission, including formal and non-formal learning settings. Particular consideration should be given to communities where formal education in the heritage language has historically been absent or discouraged.

The proposals should comprise transdisciplinary collaborations (including SSH disciplines) in resolving this issue involving, for instance and not exhaustive, linguistics, heritage and museum studies, media studies, theatre studies, literary studies, socio-economic, socio-cultural and migration studies etc. Available results of existing research on safeguarding linguistic diversity and multilingualism should be taken into consideration, while identification of needs for further research in the field should be promoted. Research could explore, among others, the role of oral transmission and its gendered component, in safeguarding languages at risk and methods to ensure its conservation. This is particularly relevant for languages where oral storytelling, music, and intergenerational dialogue play a central role in cultural transmission.

The projects should have a dedicated place for linguistic cartography (meaningful representations of linguistic diversity) and explore what are the challenges of assigning language to space; current language mapping projects, and what are the opportunities for improving language mapping with current technology.

The projects could explore how language maps could serve as educational or research tools, to provide illustrations of linguistic and cultural diversity. Pursuing cultural awareness and cultural diversity understanding makes language mapping a significant research objective.

Proposals should develop recommendations for promoting multilingualism in our societies and safeguarding of linguistic diversity, empowering citizens to take ownership for safeguarding their linguistic heritage. These recommendations should also aim at combating marginalisation of disadvantaged linguistic communities, including itinerant and stateless groups.

Proposals should build on existing knowledge, activities, networks and platforms, notably the ones funded by the EU. For example, they could include past initiatives such as the 1996 Euromosaic study. The study documented the linguistic diversity of the 12 original EC countries and later of newer members which joined the EU. The Mercator European Research Centre on Multilingualism also carried out many regional EU-funded dossiers, which would benefit from updating.

Synergies could also be created with the European Data Space for Languages and the ALT-EDIC initiative. 105

Furthermore, links should be established and synergies sought with closely related actions, such as relevant R&I actions funded by Horizon Europe or Horizon 2020. In particular, proposals should establish links to, and where appropriate build on findings from, projects funded under the topics HORIZON-CL2-2022-HERITAGE-01-01: Safeguarding endangered languages in Europe and ‘HORIZON-CL2-2024-HERITAGE-01-05: Strategies to strengthen the European linguistic capital in a globalised world.

Proposals should engage local communities, citizens and civil society organisations, in the development of their actions, using participatory approaches.

HORIZON-CL2-2026-01-HERITAGE-07: Preventing and fighting illicit trafficking of cultural goods

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.50 and 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Due to the scope of this topic, legal entities established in non-associated third countries may exceptionally participate in this Coordination and Support Action as a beneficiary or affiliated entity and are exceptionally eligible for Union funding.

This topic requires the involvement, as beneficiaries, of:

1.at least three security practitioner 106 organisations or agencies established in at least three different EU Member States or Associated Countries, and

2.at least two scientific research institutions working on illicit trafficking in the specific field of Cultural Heritage.

For participants with practitioner status, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

Some activities, resulting from this topic, may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 107 .

Beneficiaries may provide financial support to third parties up to 15% of the EU funding. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Increased evidence collection and intelligence gathering, effective cross-border and cross-domain cooperation and uptake by the Law Enforcement Authorities (LEA) and experts of the consolidated tools and platforms within their operational systems and methodologies in accordance with the different user’s requirements.

2.Capacity building and consolidated training ecosystem, developed with concrete, validated, actionable, interactive training materials tailored to the specific needs of different user groups across EU Member States and beyond.

3.European Union law enforcement, judiciary and other competent authorities and practitioners gain a better understanding and enhanced capabilities in addressing crimes related to cultural heritage thanks to the consolidations of existing solutions, standardized and tailored trainings and workshops and practical learning materials.

4.Actionable solutions to the threat to cultural heritage trafficking by illicit excavations crime that do not necessarily amount to organised crime but are still illegal activities that considerably endanger Europe’s cultural heritage, as well as cultural heritage in third countries.

5.A robust and long-term sustainable support framework and plan which will ensure and make operational a long-term cooperation in the prevention and fight of illicit trafficking of cultural goods.

Scope: Trafficking in cultural goods is a serious crime that poses significant threats to cultural heritage, particularly in conflict and crisis areas. This illicit trade involves the illegal import, export, and transfer of ownership of valuable cultural items, including theft from institutions and private collections, looting of archaeological sites, assets laundering and forgery of cultural goods. At the EU level, combatting cultural goods’ trafficking is supported by the EU Security Union Strategy 2020-2025 108 , the EU Strategy to Tackle Organised Crime 2021-2025 109 , the EU action plan against trafficking in cultural goods 110 and the related Council Conclusions 111 , 112 , 113 , the EU Serious and Organised Crime Threat Assessment (EU-SOCTA) 114 . Cultural goods’ trafficking is a highly specialised criminal market. The criminals range from specialised criminal networks to corrupt dealers or expert dark web traders. Criminal networks and actors active in the area of cultural goods trafficking are characterised by a high degree of expertise and specialised knowledge 115 . To overtake the challenges there is the necessity to use advanced analytics, including machine learning and AI technologies, in order to curate, process and share large volumes of dynamic interoperable and high-quality data and transforming it into meaningful intelligence. By facilitating data exchange across borders and between stakeholders, it would ensure real-time access to relevant information, enhancing collaboration and coordination.

Proposals should strongly build on existing expertise and developments, focusing on (1) developing a cohesive ecosystem to be promoted among LEAs, with integrations and operational interfaces between existing tools, systems (including LEA systems) and the solutions developed to trace, protect, safeguard and repatriate goods, including methodologies for combating crimes through data and network analysis; (2) fostering the utilisation of the aforementioned systems by LEA and push them forward to market readiness level to ensure their effective impact on combating illicit trafficking cases; (3) strengthening the collaboration between the different stakeholders providing effective tools and actionable and standardized training materials for boosting capacity in cataloguing and provenance information analysis; (4) improving data quality, robust data governance and data interoperability across stakeholders and cross borders, improving LEA access to critical databases; (5) provide support to evidence collection thanks to the analysis and interpolation of different sources of information and open source and geospatial intelligence.

Proposals should design and consolidate the solution space, tools and the training ecosystem to demonstrate real uptake and adoption and ensure they reflect the priorities of diverse personas, including law enforcement authorities, customs officials, police authorities, cultural heritage professionals, policymakers and citizens. The training ecosystem should build on the results and findings of relevant national and EU-funded projects, such as for example OPFA-CULT 116 , in order to leverage existing knowledge and avoid duplication of effort. The development of these materials should be integrated with existing EU and international legal frameworks and measures on the trafficking of cultural goods, including those applicable beyond EU borders 117   118   119 . For police authorities’ training-related aspects, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding.

The proposals should build on the achievements and findings of related previous national and EU-funded projects as well as create complementarities or synergies with projects and European research infrastructures in the field, such as, for example the ones funded under Horizon Europe Cluster 2 and Cluster 3, ERC, the Internal Security Fund (ISF), Creative Europe, the Union Civil Protection Mechanism (UCPM), the European research infrastructure for heritage science (E-RIHS). Where possible and relevant, synergy-building and clustering initiatives with successful proposals in the same area should be considered, including the organisation of international conferences in close coordination with the Community for European Research and Innovation for Security (CERIS) 18activities and/or other international events.

Proposals are encouraged to seek synergies, and collaboration, with relevant initiatives already developed from international stakeholders working in the field of cultural heritage as well as in the security sector. The creation of new tools and the duplication of existing ones should be avoided; instead, priority should be given to leveraging opportunities for consolidation and maximizing impact. of existing tools and resources.

Scientists and practitioners doing research in the field of Cultural Heritage (such as archaeologists, museologists, art historians or related fields) must have an essential role in the production of the outputs assuring that they efficiently take into account the real needs and problems of the field, as well as in ensuring scientific quality of information and data.

Proposals are encouraged to actively collaborate, create synergies and developments with the European Collaborative Cloud for Cultural Heritage (ECCCH) 120 and the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community. Proposals should ensure alignment on the formats and standards used to exchange interoperable high-quality data with the Cultural Heritage Cloud.

Beneficiaries may plan their activities opting to provide Financial Support to Third Parties in order to support practitioners (such as Police Authorities, Non-Governmental Organisations/Civil Society Organisations, cultural and creative industries [CCIs], research groups and communities of practitioners in the field of Cultural Heritage) for expanding the proposed work in terms of, for instance, additional user groups and needs, complementary assessments, technology- or methodology-testing activities.

Proposals funded under this topic are expected to actively develop, configure and implement a long-term sustainable governance and cooperation framework which will ensure long term engagement beyond the duration of the funding. Particular emphasis should be placed on the co-creation of a detailed, realistic, and jointly agreed roadmap and validated business model to ensure functionality after the project ends. The model needs to be already validated and operational before the end of the funded project. The scope of the research should include under-studied regions, zones in conflict areas and under environmental disasters, considering existing initiatives, for example the Recommendation on Safeguarding Cultural Heritage in Ukraine 121 .

EUROPE’S SUSTAINABLE PROSPERITY AND COMPETITIVENESS

HORIZON-CL2-2027-01-HERITAGE-01: Towards a consolidated culture and creativity driven European innovation ecosystem

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.50 and 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.00 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 122 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.The number and impact of CCI 123 -driven innovations in Europe are increased thanks to a wide uptake of evidence-based measures stemming from EU-funded research. These results are followed up with appropriate assessments and Key Performance Indicators.

2.Innovation driven by the cultural and creative industries continues to be boosted beyond project funding through a long-term economically sustainable ecosystem.

3.A vision of European CCIs as an essential engine of sustainable innovation and competitiveness is broadly established, making CCIs a natural part of European, national, regional and local innovation efforts.

Scope: The transition towards a consolidated culture- and creativity-driven European innovation ecosystem represents a strategic imperative for Europe's future competitiveness and societal resilience. In an era where technological advancements alone no longer guarantee competitiveness, the CCIs emerge as essential drivers of transformative change and prosperity. It is necessary to unlock the innovative power of Europe’s cultural and creative industries both in themselves and as drivers of innovation in other economic sectors. CCIs shape new technologies and can contribute to user-driven innovation, open innovation, cross-sectoral innovation 124 and to creative entrepreneurial ecosystems for regional development. CCIs are often the first to find productive uses for new technologies and establish meaningful connections between different technologies, thus paving the way for wider uptake that improves productivity and competitiveness in the wider economy. Europe’s CCIs can thus act as a crucial technology incubator, in addition to their wider societal contributions such as to cultural wealth, social cohesion and resilience.

Significant research and innovation efforts have been made to boost CCIs and strengthen them as engines of innovation. Notably, Horizon Europe’s Cluster 2 has launched more than 30 R&I projects with the collective objective to boost a culture and creativity driven European innovation ecosystem, establishing a collaborative platform for this purpose 125 . Furthermore, the European Institute for Innovation and Technology has established a Knowledge and Innovation Community for the Cultural and Creative Sectors and Industries 126 , and a Large-Scale Partnership for the Cultural and Creative Industries Ecosystem has been set up under the EU Pact for Skills 127 .

The challenge is to build on, consolidate and complement, as appropriate, the key results such as technologies, solutions, methods, networks and platforms developed by these R&I projects and initiatives as well as by other relevant actions, with the objective to achieve long-term impact in terms of thriving CCIs that proactively engage in innovation and achieve significant economic growth.

The project funded under this topic should build on and improve existing innovation ecosystems to make them effective for the CCIs. Difficulties to properly boost CCI-driven innovation need to be overcome, such as those linked to CCIs consisting mainly of small and micro enterprises with difficulties to fit into commonly applied innovation support models based on fast-growth startups, challenges in properly valuing the IPR of CCIs, inconsistencies between cultural and innovation policies, or issues linked to the particularities of CCI entrepreneurs. Solutions should go beyond common practice in innovation support and deploy for example portfolio approaches that make clusters of organisations investable entities. The project does not need to seek standardised approaches that work across the full diversity of the CCIs and of EU Member States and Associated Countries but should allow for taking local contexts into account. Nevertheless, the project should seek to establish common principles and active knowledge exchange across Europe.

To properly follow up the results of its work, the project should develop suitable Key Performance Indicators and assessment frameworks, including with a base line for the initial situation.

In order to achieve an enduring impact, the project should ensure long-term economically sustainable ecosystems. To be effective, it is important that the project, as appropriate, builds on previous work as well as complements and links to ongoing related initiatives. The long-term sustainable ecosystems should therefore, as appropriate, build on existing networks and/or platforms, and should involve the key stakeholders, covering most EU Member States and Associated Countries as well as a wide range of CCIs. Proposals should include an outline of the sustainable and adaptable economic model envisaged, but do not need to describe it in full detail.

In order to engage entities which are not part of the project consortium, such as important innovation support actors or CCIs, projects may award financial support to third parties. Such support can only be given in the form of grants.

The Commission estimates that a project duration of at least 5 years is appropriate, in order to be able to achieve the expected long-term impacts.

HORIZON-CL2-2027-01-HERITAGE-02: AI4Creatives Support Platform: embracing a fair AI revolution

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.50 and 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 128 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.The cultural and creative sectors and industries (CCSI) have access to a dedicated European virtual AI support platform. This hub will facilitate collaboration among a strong and open network of CCSI networks, professionals, researchers, AI tech companies, creative startups, ethical AI experts, rights management infrastructures, other industries with a shared interest in the field of AI for culture and creativity and a focus on research and innovation.

2.The AI4Creatives Support Platform provides easy access to shared services, expertise, capacity building, training, and tools needed to design, develop and adopt AI solutions tailored to cultural and creative processes and needs, enhancing innovation and competitiveness.

3.Filling a gap, the platform enables the development and sharing of AI applications that adhere to EU values, principles and regulations, implementing transparency, ethical standards, promoting cultural diversity, addressing biases, and ensuring equitable access to culture and creativity.

Scope: This topic addresses the pressing need to coordinate, support, disseminate and capitalise on relevant outcomes from Horizon Europe Cluster 2-funded projects aimed to equip CCSI to leverage the digital transformation, from other relevant Horizon Europe projects, and from initiatives exploring AI in relation to CCSI under other EU programmes, such as the AI Continent Action Plan, (including AI Factories, GenAI4EU, Apply AI and the envisaged AI strategy for cultural and creative sectors and industries), AI Innovation package, and others. The aim is maximising their impact and driving innovation and competitiveness.

AI offers significant opportunities for CCSI, but challenges persist, including skill gaps, limited interaction with technology partners, structural weaknesses of CCSI, mostly small and micro enterprises with weak bargaining power against big tech providers, and limited resources to train dedicated AI models. Other challenges relate to AI ethics, transparency and intellectual property rights, including copyright. By transcending siloed approaches and establishing synergies, CCSI can take advantage of economies of scale, harness AI's potential and drive innovation. The goal is establishing a permanent, networked reference point for CCSI through a virtual support platform that builds capacity and facilitates networking and collaboration among CCSI, stakeholders, researchers, technology developers, AI ethicists, and other industries and startups, with the overall aim to enable artists, cultural professionals, creative companies and cultural organisations to engage with AI, including dealing with biases and risks. The Support Platform is expected to enable the CCSI to access and utilize available custom-made tools, quality data, resources, knowledge, training, and AI applications aligned with their specific needs and with EU principles and regulations, thus easing the adoption of appropriate innovative ethical solutions and approaches tailored to the CCSI. Among the possible functions of the Support Platform should be:

1.Disseminate or develop frameworks, standards, best practices, and toolkits serving as strategic guidance for integrating ethical AI into CCSI value chains.

2.Facilitate cross-sector collaboration, synergies, and partnerships between CCSI professionals, AI tech companies, and startups, liaising with initiatives like the European Collaborative Cloud for Cultural Heritage (ECCCH), AI Factories, research infrastructures on cultural heritage and digital humanities, European Digital Innovation Hubs, ALT EDIC and LLMs4EU, Common European Data Space for Cultural heritage and other data spaces, and other EU initiatives in this area.

3.Build and develop a solid copyright infrastructure to support the use and licensing of copyright-protected content in the context of AI.

4.Suggest education and training frameworks and provide training to foster effective AI use in CCSI. Encourage CCSI and SMEs to engage with available federated data sources, digital infrastructures, computational resources, other available platforms to develop their own AI-powered products and services.

5.Develop a roadmap for emerging challenges in AI and other emerging technologies related to culture and creativity.

6.Engage in policy dialogues with policymakers, industry leaders, and stakeholders to emphasize culture's contribution to quality, ethical, and fair AI developments.

The platform is expected to develop and operate based on a robust sustainability and business model, ensuring long-term viability beyond the initial project phase. The business model should align with the platform’s objectives, ensuring it remains accessible to diverse organisations in terms of size and resources and that funding is not dominated by special interest groups.

The project should liaise with the EIT KIC Culture and Creativity to establish synergies, exchange information, and enhance mutual outcomes and impact. It should build on Horizon Europe funded projects in the area of AI and CCSI, particularly those funded under topics HORIZON-CL2-2025-01-HERITAGE-04: Leveraging artificial intelligence for creativity-driven innovation, HORIZON-CL2-2026-01-HERITAGE-03: AI integration in CCSI work practice: catalysing innovation and competitiveness, HORIZON-CL2-2026-01-HERITAGE-04: Towards a fair and transparent market for cultural and creative content in the era of generative AI, and establish synergies with relevant projects, and initiatives supported by other relevant EU programmes, such as Digital Europe, Creative Europe and their successors. The project should conduct a pilot of the virtual platform to ensure alignment with CCSI needs, assessing technical and operational feasibility to ensure sustainability over time. The virtual Support Platform should be fully operational by the project's conclusion.

HORIZON-CL2-2027-01-HERITAGE-03: Crafting routes to a circular economy

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 3.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 10.50 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 129 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.The cultural dimension of circular economy is better understood. Cultural factors and the potential of cultural and creative sectors and industries (CCSI) are leveraged to foster circular economy in the EU

2.Scalable, sustainable and inclusive business models are developed with users and stakeholders, leveraging circular practices from CCSI for economic and environmental benefits (e.g. nature protection, reducing waste, increasing resource efficiency, promoting sustainable consumption and re-use patterns).

3.Circular solution toolkit: A practical toolkit enables businesses in various sectors to apply CCSI-inspired frugal innovation principles, promoting circularity, sustainability and inclusion.

4.Evidence-based recommendations and guidelines are available to policymakers to support the transition towards circular practices in CCSI and across other industries and to integrate frugal innovation 130 in circular economy strategies. They emphasize local adaptations of global strategies, allowing for customized approaches that respect and enhance local cultures, heritage and economies.

5.Skills Enhancement: Training modules on frugal innovation, circular design, and circular economy practices inspired by crafts, local heritage and other CCSI are available to professionals in various industries.

Scope: The transition from a linear to a circular economy 131 is crucial for Europe’s prosperity, long term competitiveness and strategic autonomy. This shift can reduce dependence on raw materials, decrease greenhouse gas emissions, pollution, and waste, limit biodiversity loss, create jobs, and support environmental sustainability. The New European Innovation Agenda 132 recognises circularity as a key challenge to accelerate innovation across the EU. Securing essential resources is a high priority, but the transition to circularity requires more than new materials and products: it demands a paradigm shift and a systemic approach that combines different sectors, technological progress, actors, and disciplines with deeper industrial, economic, and societal changes. In advancing a circular economy and society, cultural dimensions are paramount; and cultural barriers can be as significant as economic or technical ones and should be addressed.

CCSIs can act as catalysts for change. Through storytelling and community engagement, they can reshape cognitive frameworks, influence consumer attitudes, and promote societal shifts towards circular principles. They can encourage other industries, such as manufacturing (including textile and fashion), tourism, or construction (including housing and urban development) to adopt circular approaches, promoting resource efficiency and designing for longevity and adaptability. Despite their potential, cultural aspects remain underexplored in circular economy strategies. This topic aims to investigate effective strategies and synergies between culture, creativity, and the circular economy, to inform policy, enhance education and lifelong learning, and inspire innovation. The goal is to develop robust frameworks supporting economic, environmental, and social sustainability across Europe, fostering an environment where culture, creativity, and economy combine to form resilient circular systems and societies. Where relevant, synergies with the New European Bauhaus may also be considered.

Proposals may address one or more of the following four focuses and may combine them with others as appropriate to their objectives.

Focus 1. Crafts-led innovation for circular economy

Crafts naturally align with circular economy principles through their use of natural, renewable materials, small scale tools and production, and the creation of durable products with cultural significance. Integrating circular economy concepts with craftsmanship helps address sustainability challenges, preserve cultural heritage and foster local economic development. Craft practices exemplify frugal innovation by efficiently using local resources and minimising waste, offering valuable insights for other sectors seeking to improve sustainability and resource efficiency. Key aspects of the relationship between crafts and the circular economy include traditional knowledge systems rooted in generations of sustainable, place-based practices; local resource utilisation promoting efficiency; and upcycling and waste reduction through creative reuse of materials.

Furthermore, craftmanship is key part of the value chain in high-end industries such as fashion and textiles, with potential synergies to enhance sustainability and the use of recycled, reused and renewable materials and to foster circular and just fashion and textiles value-chains, supporting innovative approaches.

By leveraging circular economy and frugal innovation principles, craft practices offer affordable, accessible, inclusive and equitable solutions to sustainability challenges, emphasizing local resources and community-based production.

Collaborative, open innovation approaches can unlock creative solutions that promote a more sustainable, inclusive, and resource-efficient future.

Proposals should develop a framework integrating circular economy and frugal innovation principles derived from craft practices, applicable and adaptable across various industries and sectors. This includes models for cross-sector collaboration and knowledge transfer among craft practitioners, designers, researchers, and industry professionals to drive circular innovation, foster capacity building, and ensure equitable access to sustainable solutions.

Proposals may consider UNESCO Creative Cities, in particular the City of Crafts and Folk Arts.

Focus 2 Evaluating adaptive reuse of built cultural heritage

Cultural heritage buildings are vital for their historical and cultural significance, embodying the identity of local communities. At the same time, the built environment is a major driver of material demand, with significant economic, environmental and wellbeing impacts. 133 The Built4People SRIA 134 highlights the need for R&I in retrofitting and repair, including heritage buildings, using vernacular, bio-based, locally sourced materials, or innovative materials compatible with vernacular ones. The EU Circular Cities and Regions Initiative identifies adaptive reuse of cultural heritage as key to urban sustainability and resilience. 135   There is a need for systematic urban planning transforming building lifecycles from linear to circular models, leveraging cultural heritage to improve energy efficiency, reduce waste, and generate cultural, economic, social and environmental benefits. Participatory planning is crucial for achieving circularity, as are indicators for measuring impact. Adaptive reuse also delivers economic value as heritage sites attract visitors, support local businesses, and foster vibrant cultural economies, making cultural participation central to sustainable urban regeneration and the circular economy. Integrating service design approaches can further connect adaptive reuse of heritage buildings with stakeholders and enhance cultural services and community activities.

Proposals should develop methodologies to evaluate the economic, social and environmental benefits of maintaining and reusing built heritage. They should establish criteria and indicators for assessing cultural heritage’s contribution to circular city objectives, including energy and resource efficiency, waste reduction, social cohesion and economic sustainability, and explore evaluation tools for innovative circular financing, business and governance models for adaptive reuse of cultural heritage.

Focus 3. Food heritage and gastronomic innovation for circular futures

Food is deeply connected to cultural and creative sectors through gastronomic heritage, food-related crafts, and intangible traditions that shape cultural identities. Addressing food’s cultural dimensions offers unique opportunities to advance circular economy principles. Food heritage promotes local sourcing, biodiversity, and waste reduction, while culinary tourism and creative food initiatives drive sustainable growth and cross-sectoral innovation. Proposals should develop a framework to integrate circular economy principles into gastronomy and food heritage and devise transferable methodologies linking food-related creativity with sustainable practices. Proposals might consider UNESCO Creative Cities, in particular the City of Gastronomy.

Focus 4. Designing circularity: creative pathways and open innovation

Design is pivotal in the transition to a circular economy, underpinning three principles: eliminating waste and pollution, circulating products and materials, and regenerating nature. By applying these principles, designers create durable, repairable, and recyclable products and services, aligned with circular economy goals. The fashion industry pioneered upcycling and make-to-order models, producing items only on demand to reduce overproduction and waste. Such models, alongside product-as-a-service, sharing economy initiatives, or closed-loop production systems, offer adaptable strategies for other sectors to enhance circularity. The dynamic creative sector catalyses innovation, serving as a platform to experiment with circular design approaches across creative and non-creative sectors, including open innovation practices.

Proposals should develop a comprehensive framework for integrating circular economy principles into design processes across cultural and creative industries, guiding designers to minimise waste and maximise resource efficiency. A collaborative environment should facilitate sharing circular design practices and transferring innovative solutions across industries.

SUPPORTING PEOPLE, STRENGTHENING OUR SOCIETIES AND OUR SOCIAL MODEL

HORIZON-CL2-2027-01-HERITAGE-04: Culture, heritage and creative industries for health and well-being

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 16.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 136 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Deepened knowledge of the potential positive effects of cultural experiences on health and well-being 137 is developed and made available to relevant stakeholders, along with validated scalable and replicable practices to reinforce these effects

2.Key industrial, health, cultural, educational and/or civil society actors are aware of validated systemic approaches to make cultural experiences improve health and well-being and are engaged in producing or supporting such cultural experiences

3.Competitive European cultural and creative sectors and industries systematically contribute to improve health and well-being

Scope: It is widely recognised that cultural experiences, such as those offered by cultural heritage institutions (CHIs) or cultural and creative sectors and industries (CCSI), can be beneficial for health and well-being. Research done, though scattered and not always systematic, supports this conclusion, with for instance the World Health Organisation arguing that cultural experiences contribute to health in four areas: prevention of ill-health, promotion of healthy behaviour, as well as management and treatment of disease 138 .

However, there is still a lack of systematic research into the key characteristics and circumstances of cultural experiences to best support health and well-being. The challenge is to remedy this situation by developing evidence-based and validated practices that can be understood and used by CHIs and CCSI as well as other key stakeholders to develop cultural experiences that effectively support health and well-being.

There are many possible ways to approach this challenge. Proposals are free to choose the focus considered to have the best potential to achieve a strong impact and should make sure to delimit the focus in a way that allows for sufficiently thorough work. Activities may thus concentrate on different kinds of arts and culture – interventions and/or experiences – online and/or in person – and/or on cross-sectoral issues. Proposals should, however, credibly explain why the chosen focus and approach are likely to achieve a strong impact.

One possible focus could be on arts and culture-based experiences as a societal support kit, in situations of crises or other circumstances where health or well-being is under threat. Decision-makers could thus benefit from a set of validated practices that help support well-being among the population in such situations. Such research might be based on good examples provided by Member States/Associated Countries or other stakeholders, with a view to consolidate and build on existing knowledge and practices.

Another possible focus could be on mobilising a particular cultural and creative industry to contribute to health and well-being, such as for instance the video games industry. Ever more people spend ever more time on games, making this an important and growing source of cultural experiences, with a strong interactive component. Besides being a source of entertainment, video game communities give opportunities for isolated, underprivileged or discriminated people to find a sense of belonging, and to contribute to societal goals. At the same time, however, a context of competitivity and anonymity may invite harassment and discrimination in online multi-player video games.

A third possible focus could be an implementation research approach, exploring the obstacles to adoption of already validated arts and culture –based intervention(s) that support health and well-being, and developing effective way(s) to achieve broad uptake.

In order to achieve evidence-based and validated practices that can be understood and used by CHIs and/or CCSI as well as by other targeted key actors and stakeholders, projects should involve stakeholders from such sectors. To validate practices, projects may launch small scale pilot trials but may also choose other validation methods appropriate to the focus chosen. As appropriate for the focus chosen, projects should properly take the gender dimension into account, such as for instance gender differences in cultural participation and its consequences. Projects may award financial support to third parties in order to involve entities such as CCSI, CHIs or other important stakeholders which are not part of the project consortium. Such support can only be given in the form of grants.

To the extent appropriate, projects should build on previous research and innovation and established methods. In particular, as appropriate, projects may establish links to the project funded under call topic ‘HORIZON-CL2-2025-01-HERITAGE-09 Impacts of Culture and the Arts on Health and Well-being’.

Proposals may consider, as appropriate considering the focus chosen, the involvement of the European Commission's Joint Research Centre (JRC), based on its experience for example with the SciArt and artist-in-residency programmes, and the value it could bring in providing an effective interface between research activities and policymaking.

HORIZON-CL2-2027-01-HERITAGE-05: Re-imagining the creative economy: the interplay between the cultural and creative sectors and industries and the social economy

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 3.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 10.50 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 139 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Evidence-based policy frameworks and guidelines promoting the convergence of creative and social economy models.

2.Case studies, indicators, and evaluation methods to measure the social and economic impact of CCSI in social economy frameworks. These tools are provided for policymakers and stakeholders, with areas for improvement identified.

3.Hybrid CCSI business models that incorporate social economy principles, balancing profitability and social responsibility, showcasing scalable examples across different regions and sectors.

4.Workforce development strategies addressing precarious employment in creative sectors, including alternative employment structures, skill-sharing, and professional development, and enhancing socio-economic diversity and mobility in creative industries, using gender-sensitive and intersectional approaches to address inequalities.

Scope: The intersection of social economy 140 ] and the cultural and creative sectors and industries (CCSI) provides fertile ground for advancing sustainable and inclusive development across public and private domains. Enhancing synergies between private initiatives (impact-oriented enterprises, cooperatives, associations) and public policy can unlock innovative models, fostering hybrid approaches that blend public mission with entrepreneurial strategies. Studies highlight the role of social economy entities in CCSI for local development through ecological approaches, territorial clustering, and community engagement, as well as for improving employment and working conditions and promoting inclusive growth 141 .

The European Commission’s 2021 Action Plan for the social economy, complemented by the EU Social Economy Gateway 142 , and the Organisation for Economic Co-operation and Development (OECD) underscore the CCSI potential for economic growth, job creation, and innovation. The OECD further notes that integrating social economy models in culture and creativity can stabilise employment, improve working conditions in creative industries, which often face precarious employment and limited access to credit, and foster sustainability, innovation and social cohesion 143 . In April 2023, the UN General Assembly recognised the social economy as critical to inclusive and sustainable economies 144 .

Embracing social economy principles in CCSI can address major societal challenges such as income inequality and social cohesion, while driving culture- and creativity-led innovation and inclusive growth across Europe.

Reimagining the creative economy requires CCSIs to engage with broader societal and economic frameworks. This topic aims to enhance the transformative potential of CCSIs’ interplay with the social economy in Europe. Proposals are expected to investigate, develop, and test innovative frameworks and models that leverage social economy principles in culture and creativity to drive social impact, economic sustainability, quality jobs creation, and vibrant, resilient cultural and creative sectors. By moving beyond traditional market logics and adopting cooperative, participatory and socially oriented models, proposals will identify scalable strategies for ethical business, revenue diversification, and embedding social purpose in creative innovation. This may include developing technical or legal assistance and support services enabling CCSIs to access shared resources, enhance resilience, and build community capital. These efforts will empower CCSIs to catalyse inclusive, sustainable transformation and position Europe as a leader in a fairer creative economy.

Key areas of focus are expected to be addressed through inter-, multi- and trans-disciplinary approaches (taking into account – among others – contributions by SSH disciplines), including cross-sectoral cooperation and stakeholder involvement:

1. Sustainable Growth and Quality Employment

1.Analyse social economy models’ impact on CCSI sustainability, resilience, and growth, particularly during crises.

2.Examine how social economy principles address precarious employment, support alternative employment, and foster professional development, while contributing to creative entrepreneurial ecosystems for regional development that strengthen local economies.

3.Explore financing mechanisms, fiscal incentives and solutions to sector-specific challenges, to incentivize social reinvestment.

4.Investigate how social economy enterprises address socio-economic diversity, income inequality, inclusivity, and promote innovation including within CCSIs. 145  

2. Innovation, local development and social impact

1.Investigate how CCSI social enterprises drive innovation (including social innovation), social participation, and empower marginalized groups and groups in vulnerable situations, such as persons with disabilities.

2.Highlight social entrepreneurship’s role in catalysing new business models and value-driven practices addressing societal challenges

3.Assess CCSI social economy enterprises contribution to local development, social cohesion, and responsible consumption.

3. Policy and comparative studies

1.Analyse and compare policy frameworks supporting the convergence of creative economy and social economy models in the EU and beyond.

Identify best practices and propose recommendations for integrated strategies enhancing sustainable, inclusive development and innovation.

HORIZON-CL2-2027-01-HERITAGE-06: Future-proofing sustainable cultural tourism

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.00 and 4.80 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 14.50 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 146 .

Expected Outcome: Projects should contribute to the first expected outcome, plus those under either Focus 1 or Focus 2, depending on the chosen focus

1.Evidence-based policy recommendations and solutions for integrating cultural tourism into strategies for regenerative sustainability, environmental protection (for example, from degradation or biodiversity loss), digital transformation, social inclusion and gender equality at all levels of government. As a result, cultural tourism becomes a stronger driver of regenerative sustainable development, increases workforce numbers and skills, and improves working conditions. Research impact is maximised through coordinated dissemination and policy co-creation, facilitating implementation of research-based solutions by policymakers and stakeholders.

Focus 1

1.A comprehensive analytical framework for ethical AI integration in sustainable cultural tourism balancing sustainable competitiveness with cultural authenticity and inclusivity.

2.Methodological frameworks and tools for AI-assisted foresight in cultural tourism enabling policymakers, civil society and stakeholders to anticipate changes and adapt strategies proactively.

Focus 2

1.Evidence-based, community-centric models and strategies for sustainable cultural tourism in emerging and less-developed destinations, adaptable to diverse contexts within and beyond the EU.

2.An international collaborative network for small business and civil society in cultural tourism, focused on cross-border partnerships, regenerative practices and equitable benefit-sharing. This network will connect stakeholders with researchers, policymakers, expertise, and resources to co-create culturally respectful, regenerative cultural tourism models and improve workforce conditions in underserved regions.

Scope: Cultural tourism accounts for about 40% of global tourism 147 and continues to grow as travellers seek unique, authentic, and immersive experiences. In addition to its economic benefits, cultural tourism enriches societies through cultural exchange and cross-cultural understanding. The sector faces major transformation driven by technological advancement, shifting consumer expectations, climate change, sustainability imperatives, environmental degradation and threats to cultural integrity – including commodification and heritage degradation. Furthermore, there is a growing emphasis on inclusive and meaningful travel experiences, including accessibility for travellers with disabilities and others with specific needs. This topic takes a multidimensional approach to future-proofing sustainable cultural tourism amid technological, social and environmental change across the EU and beyond. Proposals should select either Focus 1 or Focus 2 and clearly state their selection:

Focus 1: Transformative AI integration and strategic foresight for cultural tourism resilience

Proposals are expected to explore how integrating AI-powered tools and other emerging technologies with cultural tourism can strengthen its resilience, inclusivity, and sustainability. Additionally, through AI-assisted participatory foresight proposals should address the need for tourism systems to move from reactive management to anticipatory governance models, building resilience to global challenges.

Proposals should investigate AI applications that reshape cultural tourism experiences while ensuring that they remain authentic and respectful of local integrity; enhance inclusivity, including equal access to technology and improved accessibility for persons with disabilities; help manage visitor pressure. They could leverage available public and private data and infrastructures, such as the European Data space for Tourism. 148  Building on recent developments in AI and immersive technologies, proposals could for example use AI-powered virtual and augmented reality to boost visitor engagement and cross-cultural appreciation of cultural sites while preserving historical integrity. They should investigate novel approaches to AI-driven personalisation that develop inclusive, non-discriminatory, tailored cultural experiences, which are ethically managed, and ensure fair representation of minority or lesser-known heritage and cultural expressions.

Proposals could analyse the integration of AI in multilingual interpretation and cultural mediation to overcome language barriers and deepen cultural understanding of local contexts or develop and refine AI-powered tools for visitor flow management, real-time heritage monitoring, and balancing preservation with inclusive tourism.

Furthermore, proposals are expected to develop methodological frameworks for applying AI-assisted foresight (scenario planning, horizon scanning, among others to anticipate trends and challenges in cultural tourism – such as shifts in visitor behaviour, cultural commodification risks, and potential disruptions (eg related to climate, pandemics, energy crises), enabling the identification of opportunities and risks and fostering proactive, data-informed policy responses. AI-based predictive analytics should be combined with participatory workshops to engage local communities, authorities, and cultural organisations in co-creating forward-looking sustainable tourism strategies.

Focus 2: Cultural tourism as a catalyst for sustainable local development

Proposals are expected to develop sustainable cultural tourism frameworks and strategies tailored to emerging and less-developed destinations, especially in low-income and lesser-known regions seeking to leverage culture and creativity for economic growth and social development, including through addressing depopulation and preventing overtourism. These frameworks may foster creative entrepreneurial ecosystems for regional development. Partnerships with non-EU countries are encouraged. Proposals should investigate cross-border collaboration models that enable mutual learning, upskilling, fair working conditions, knowledge transfer and capacity building between EU and non-EU partners. Proposals should identify and adapt proven sustainable cultural tourism models to diverse less-developed settings (urban, peri-urban, rural) emphasizing equitable benefit-sharing. The research should include the analysis of case studies of successful community integration in cultural tourism decision-making. Partnerships among local communities, creative industries (including crafts), local businesses and cultural heritage organisations should be prioritised to co-create economically viable, environmentally balanced, authentic and culturally respectful tourism offerings, potentially using living labs and pilot demonstrations. Projects are expected to establish collaborative networks for small businesses and civil society actors in cultural tourism, supporting them through access to researchers, policymakers, expertise, knowledge, resources and collaborative opportunities.

Regardless of focus, all proposals should ensure cooperation with and policy uptake of existing knowledge, tools, and best practices from past and ongoing EU-funded research on cultural tourism and related areas 149 . They should develop frameworks integrating cultural tourism with broader sustainability, digital transformation, and social inclusion goals. Furthermore, they should create co-creative policy development methodologies involving diverse stakeholders (policymakers across various government levels, local communities, NGOs, businesses, industry) to translate research insights into evidence-based strategies and contextually appropriate interventions boosting cultural tourism as a resource for sustainable development and fostering workforce growth and skills, and improved working conditions in cultural tourism. Finally, they should establish continuous knowledge exchange mechanisms among researchers, practitioners, and policymakers to ensure ongoing relevance and impact.

HORIZON-CL2-2027-01-HERITAGE-07: Societal impact of cultural heritage

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 2.50 and 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 15.00 million.

Type of Action

Research and Innovation Actions

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio, grants will be awarded to applications not only in order of ranking but at least also to those that are the highest ranked within each area provided in the scope (A, B and C), provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 150 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Enhanced understanding of the societal impact of cultural heritage; Good practices and case studies to enable positive societal impact described and documented, for the context of the research area chosen.

2.Capacity building and knowledge dissemination among practitioners and policymakers.

3.Produce and disseminate policy recommendations, guidance, and toolkits, supporting policymakers, in. the context of the research area chosen as appropriate.

Scope: Heritage is a dynamic resource that can foster societal resilience, intercultural dialogue, and a sense of belonging in increasingly diverse and fragmented societies. It can contribute to social cohesion and resilience through arts, design and cultural practices. Thus, cultural heritage is central to the preservation of the social fabric and community cohesion. Understanding and amplifying the societal impact of cultural heritage is essential for reinforcing identity, cohesion, and global leadership based on shared values. Research proposals should explore how cultural heritage actively shapes civic engagement, social innovation, collective memory, and the transmission of democratic values.

Moreover, it is crucial to develop new narratives around heritage — ones that are forward-looking, critically aware, and deeply connected to Europe's evolving values. Such work will not only strengthen Europe's internal cohesion but also position cultural heritage as a strategic asset in addressing global challenges.

In this context, social innovation could also translate into working with cultural heritage practitioners and custodians to explore how cultural heritage can solve some of today's societal challenges (achieving better social inclusion, social cohesion, well-being, and equality). Whereas previous research (including contributions by SSH disciplines) has widely explored developing heritage-based education, contribution of culture to rural development and cultural tourism, there are some fields that could benefit from more research: cultural participation and access to culture, with a focus on young people; gender roles and identities; a shared cultural heritage and shared responsibility in the light of security challenges.

Research projects should choose one of the following areas:

A. Cultural participation and access to cultural heritage

Access to culture, acquired through socialisation and education, plays a crucial role in shaping cultural practices and preferences. As mentioned in the Political Guidelines 151 for the European Commission, there is a need to improve access to cultural heritage, in particular for young people, and contribute to tackle cultural inequality and strengthen a sense of identity and belonging. In addition, attention should be paid to disadvantaged groups, eventually solidifying participatory culture and democracy and fostering a sense of stewardship towards cultural heritage.

A Special Eurobarometer on Europeans’ Attitudes Towards Culture 152 , published in May 2025, showed that a majority of Europeans believe that their country and the EU should work more closely together when it comes to making arts and culture more accessible to everyone.

Prior research 153 indicates that increased cultural participation can potentially enhance civic engagement, social inclusion, and democratic governance, and counteract alienation and social disengagement. However, research also indicates profound and multifaceted barriers to access. These barriers include, for example, geography, including the challenge of rural isolation; under-representation of minority groups; economic disparity.

The proposals should explore good practices for fostering access to cultural heritage, with a focus on young people and ways to empower them to take an active role in their communities and strengthen social cohesion. Proposals should also explore which are the main barriers for access to culture and effective means to increase cultural participation, identifying specificities for different types of groups.

The proposals should employ interdisciplinary and participatory methods to identify effective models for inclusive cultural participation. Results are expected to guide policies on cultural access, with recommendations, for instance, for digital infrastructure, educational programmes, and cross-sector collaboration to foster inclusive citizenship.

B. Gender roles and identities

Cultural heritage has the power to promote diversity and inclusion by showcasing diverse narratives and histories, but it can also perpetuate inequality if stereotypes, cultural role models, and representations are limited or biased, silencing marginalised voices.

The proposed research should explore the complex relationships between cultural productions, representations and societal attitudes towards different sexes and gender identities, with a focus on understanding how culture can shape our cultural landscape and influence our attitudes and imaginaries.

Proposals should provide an analysis of the representation and overview of different gender identities and intersecting factors such as racial or ethnical background, disability or socioeconomic background, in cultural fields. Proposals should explore how gender aspects have been absent, or forgotten, in major supranational cultural narratives. Proposals should provide actionable recommendations on how to promote a more inclusive and diverse representation, including in the cultural content, and to address the absence of diverse representations in the cultural field. These recommendations should be developed in a dialogue with different stakeholders, for example researchers, policymakers, cultural heritage institutions, civil society representatives.

C. Cultural heritage, cohesion and security

The proposed research should explore the role and conceptualisation of cultural heritage as a distinctive element of our shared identities and democratic values. It should also examine the links between culture and security including issues of disinformation and foreign information manipulation and interference (FIMI) etc. Proposals are expected to explore the notions of shared heritage and shared responsibility as an expression of our social interdependence, and culture as a factor of union and cohesion.

Cases of instrumentalisation of cultural heritage and the political influence on museums or other cultural institutions should also be taken into account in the research. Culture can also face factors of destabilisation, attacks on cultural heritage can destabilise society and jeopardize security while cultural content can greatly influence public opinion and the imaginaries. The proposals should explore how to deal with polarising narratives and controversial aspects of cultural heritage use.

The proposals should propose good practices, policy guidelines, run pilot projects and propose didactic materials to raise awareness on existing challenges, enhance “neutrality” in cultural heritage management, collective responsibility and cultural resilience; explore the notions of care and repair applied to cultural heritage.

Proposals shall clearly indicate the thematic area they have selected to work on.

Proposals should adopt a multidisciplinary approach (involving, for instance and not exhaustively, heritage and museum studies, cultural anthropology, ethnology, media studies, theatre studies, literary studies, musicology etc.) to assess and demonstrate how cultural heritage initiatives contribute to societal well-being, community empowerment, inclusion, and sustainable development while identification of needs for further research in the field should be promoted.

Proposals should prioritize empirical research, participatory methodologies, and policy innovation to maximize and communicate the transformative power of cultural heritage across all layers of society.

Proposals should connect to both formal and non-formal education, particularly arts education. Encouraging collaboration between cultural heritage actors and educational institutions would enhance impact.

Proposals should build on existing knowledge, activities, networks and platforms, notably the ones funded by the EU, for example paying attention to the future digital tools and platforms provided by the European Collaborative Cloud for Cultural Heritage (ECCCH), and the Common European Data Space for Cultural Heritage.

Furthermore, links should be established and complementarities sought with closely related actions, such as relevant R&I actions funded by Horizon Europe or Horizon 2020.

HORIZON-CL2-2027-01-HERITAGE-08: Safeguarding & transmission of intangible cultural heritage

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 154 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Enhanced understanding of the state of play of the safeguarding of Intangible Cultural Heritage (ICH), in the Context set by the 2003 UNESCO Convention, and an overview of successful methods for documenting and ensuring the transmission of ICH, including digital, audio-visual, and advanced technologies.

2.Recognition of the significance and value of ICH in different social, cultural and economic contexts, and with attention to biodiversity preservation and links between ICH and the natural environment.

3.Empowered communities take ownership and responsibility for safeguarding their ICH, with a focus on how inter-generational transmission is ensured, and on youth involvement and informal education.

4.Innovative policy solutions are available, for the safeguarding of ICH and for mobilising ICH as a resource for fostering social and economic innovation, biodiversity protection and restoration.

Scope: Intangible cultural heritage (ICH) refers to ‘the practices, representations, expressions, knowledge, skills—as well as the instruments, objects, artefacts and cultural spaces’ that are ‘transmitted from generation to generation’ and are ‘constantly recreated’ – as defined by the United Nations Educational, Scientific and Cultural Organisation (UNESCO) Convention for the Safeguarding of the Intangible Cultural Heritage (ICH Convention) 155 . ICH is an essential part of a community's identity and is a vital component of its cultural and biological diversity.

The ICH Convention was adopted in 2003, by 148 countries and it recognizes the importance of ICH as a driving force for social cohesion, cultural diversity, and sustainable development.

However, the nature of ICH, as living heritage, to continually transform and evolve, makes it particularly challenging to keep alive. Therefore, safeguarding ICH encounters very different challenges than the built heritage sector. ICH is rooted in territories and communities and is essential for identity building and maintaining social cohesion and a harmonious relation to the natural environment. It is a source for creativity and innovation, and a critical factor for new competitive scenarios.

Transmission, education and intergenerational dialogue play a key role in this context, and there is an urgent need to research and foster participatory approaches, especially involving oral cultures and transmission. Different case-studies should explore various approaches to the safeguarding of ICH, considering the specific nature of competences, knowledge and cultural practices of creators and knowledge holders, with a focus on intergenerational transmission.

Proposals should contribute to defining the specificities of intangible cultural heritage. Additionally, they could examine and quantify the contribution of ICH to creativity, innovation, cultural and biological diversity, and economic benefits. Proposals should also contribute to the rethinking of cultural policies for the safeguarding of ICH including exploring links and correlations between cultural and biological diversity.

Proposed research projects could address in depth the following research questions:

1.What is the state of play of the safeguarding of ICH in Europe, following the UNESCO 2003 Convention?

2.What are the main threats and challenges to the erosion and loss of ICH in Europe?

3.What are the most effective strategies for securing ICH safeguarding initiatives?

4.How can advanced digital technologies be leveraged for the safeguarding & transmission of ICH?

5.How can ICH provide inspiration for innovative approaches to existing societal challenges (e.g. competitiveness, intergenerational dialogue democratic values, biodiversity protection and restoration 156 )

6.What role can community-led initiatives play in safeguarding ICH, and how can communities be supported and empowered to safeguard it?

The role of advanced digital technologies to support ICH safeguarding and transmission should be considered, as appropriately.

The proposals should comprise transdisciplinary scientific collaborations involving, for instance and not exhaustive, heritage and museum studies, cultural anthropology, ethnology, media studies, theatre studies, literary studies, musicology etc. Available results of existing research on intangible cultural heritage should be taken into consideration, while identification of needs for further research in the field should be promoted.

Proposals should build on existing knowledge, activities, networks and platforms, notably the ones funded by the EU, for example paying attention to the future digital tools and platforms provided by the European Collaborative Cloud for Cultural Heritage (ECCCH), and the Common European Data Space for Cultural Heritage.

Furthermore, links should be established and complementarities sought with closely related actions, such as relevant R&I actions funded by Horizon Europe or Horizon 2020. In particular, proposals should establish links to, and where appropriate build on findings from, projects funded under the topics HORIZON-CL2-2025-HERITAGE-02: Innovative approaches to intangible cultural heritage for societal resilience.

HORIZON-CL2-2027-02-HERITAGE-09-two-stage: Open topic: Impact-driven research on realising the full potential of cultural heritage, arts and cultural and creative industries

Call: Culture, Creativity and Inclusive Society - 2027 - Two-stage

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 2.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 20.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 157 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to the following expected outcome:

1.New groundbreaking findings and methods are developed, verified and put into practice that significantly contribute to realising the full potential of cultural heritage, arts or/and cultural and creative industries (CCIs) 158 as drivers of sustainable innovation and/or a European sense of belonging.

Scope: Applicants are invited to design the best possible and groundbreaking research and innovation to achieve that the full potential of cultural heritage, arts and/or cultural and creative industries as drivers of sustainable innovation and/or a European sense of belonging is realised.

Applicants are free to choose the focus that best addresses the expected outcome; it can be limited to certain areas or issues or be broader. However, research under this topic should have an impact-driven focus and move beyond descriptive studies towards transformative, actionable knowledge.

As appropriate for the focus chosen, proposals should build on previous research, networks or platforms. Projects must not, however, duplicate activities already funded but should explore new areas.

Destination Innovative Research on Social and Economic Transformations

Projects funded under this destination should contribute to the following expected impacts in the Horizon Europe Strategic Plan 2025-2027 159 :

1.Strengthening social and economic resilience and sustainability

2.Boosting inclusive growth and reducing vulnerabilities effectively

The expected impacts reflect the two-pronged nature of the destination. On the one hand, research funded by this destination will improve the understanding of how the macro drivers of change (technological change, climate change, new global trade patterns, along with migration, human mobility, and other demographic changes) impact society and inform policy makers on how to mitigate negative consequences and harness newly created opportunities. The results obtained should improve the understanding of the interplay between different drivers of change and their social, ethical, political, and economic implications. The improved understanding of these challenges and their economic, social, and distributional impacts will fill in the research gaps while also inform the design and assessment of policies addressing existing and emerging challenges, including in the areas of education, well-being and mental health.

On the other hand, research and innovation investment should be geared towards deepening the understanding of how ongoing changes impact society, with a specific emphasis on the key objectives of boosting inclusive and sustainable growth and effectively reducing vulnerabilities, poverty and inequalities. This knowledge should provide valuable insights to policymakers to design and assess policies that effectively address vulnerabilities while capitalizing on emerging opportunities.

Overall, the destination’s activities will help promote the EU’s inclusive growth, resilience, and fair transition towards climate neutrality, by providing solid analytical evidence to implementing actions related to:

1.The European Pillar of Social Rights, and its Action Plan with its three ambitious targets (78% employment rate, 60% of population with yearly training, and reduction of the number of people at risk of poverty and social exclusion by at least 15 million by 2030)

2.the European Education Area and its EU-level 2030 targets

3.The Union of Skills (including envisaged initiatives on skills portability and the European Strategy for Vocational Education and Training, the Pact for Skills and the Skills Agenda)

4.the first-ever EU Anti-Poverty Strategy and the European Affordable Housing Plan

5.The Union of Equality policies and strategies, including:

1.the Strategy for the Rights of Persons with Disabilities 2021-2030 160 (in line with the United Nations Convention on the Rights of Persons with Disabilities 161 ); the European Accessibility Act (Directive 2019/882), and the European Disability Card

2.The Gender Equality Strategy 2020 – 2025 and the Directive combating violence against women and domestic violence

3.EU Anti-racism Action Plan 2020-2025

4.The Strategic EU Framework for Roma Equality, Inclusion and Participation 2020-2030

5.The LGBTIQ Equality Strategy 2020-2025

6.The Communication on Demographic change in Europe: a toolbox for action

7.The EU’s just transition policy framework, in line with the 2040 Climate Target Plan, including the Just Transition Mechanism, the Social Climate Fund, and the Council Recommendation on ensuring a fair transition towards climate neutrality

8.The new Pact for European Social Dialogue and the Council Recommendation on strengthening social dialogue in the EU.

9.The European Child Guarantee

10.The Council Recommendation on adequate minimum income

11.The Commission Communication on a comprehensive approach to mental health

12.The new Pact on Asylum and Migration and its accompanying actions, initiatives and legislation.

A new European Partnership on Social Transformations and Resilience 162 , focused on the social sciences and humanities (SSH), will be launched to make use of their potential to foster resilience, fairness and inclusiveness, and social cohesion in the light of changes in climate and environment, technology, demography, and unexpected shocks. The Partnership will fund research and innovation activities in the areas of the future of work, modernisation of social protection and essential services, education and skills development and a fair transition towards climate neutrality.

Applicants are encouraged to consider, where relevant, the services offered by the current and future EU-funded European Research Infrastructures, particularly those in the social sciences and humanities (SSH) domain 163 .

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud (EOSC), as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this research is FAIR (Findable, Accessible, Interoperable and Re-usable).

To maximise the impacts of R&I under this Destination in line with EU priorities, international cooperation is encouraged whenever relevant in the proposed topics.

Research on social and economic transformations funded by topics in the present Work Programme will build upon its predecessors in Horizon 2020 and Horizon Europe and further push the boundaries of state-of-the-art knowledge. It will do so by further engaging with a vast array of stakeholders, not limited to universities and research centres, but also extending to social partners (trade unions and business organizations), civil society organizations, practitioners, VET providers, and SMEs.

The destination will rely on a carefully balanced mix of actions, to bring together a balanced and appropriate set of stakeholders to achieve research of the highest quality, while aiming at providing recommendations to policymakers at European, national, regional and local level that could have a beneficial societal and economic impact. In order to facilitate the latter, it will maximise the feedback to policy and the dissemination and exploitation of research and innovation results and practices in the domain of social and economic transformations.

Proposals are invited against the following topic(s):

HORIZON-CL2-2026-02-TRANSFO-01: Co-funded European Partnership for Social Transformations and Resilience

Call: Cluster 2 Partnerships

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 60.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 60.00 million.

Type of Action

Programme Co-fund Action

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The granting authority can fund a maximum of one project.

Representatives of the EU institutions will be part of the evaluation committee.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The starting date of grants awarded under this topic may be as of the submission date of the application. Applicants must justify the need for a retroactive starting date in their application. Costs incurred from the starting date of the action may be considered eligible.

Beneficiaries may provide financial support to third parties (FSTP). The support to third parties can only be provided in the form of grants.

As a co-funded European Partnership, providing financial support to third parties is a core activity of this action in order to achieve its objectives. Consequently, the EUR 60 000 threshold laid down in Article 207 of Financial Regulation (EU, Euratom) 2024/2509 does not apply. The maximum amount of FSTP that may be awarded to any single third party is set at EUR 3 million for the entire duration of the action. This ceiling is justified by the fact that FSTP is a primary activity of this action, by its expected duration of 7–10 years (exceeding a standard project lifespan), and by the extensive experience gained under predecessor partnerships. However, if the objectives of the action would otherwise be impossible or overly difficult (and duly justified in the proposal) the maximum amount may be higher.

The funding rate is up to 30% of the eligible costs.

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Project should contribute to all of the following expected outcomes:

1.Research funders, policymakers and research communities in the social sciences and humanities (SSH) are provided with a multi-annual R&I programme on social transformations and resilience, responding to megatrends like climate change and biodiversity loss, digitalisation, demographic changes and unexpected shocks.

2.Research investments on social protection and essential services, future of work, education and skills, and a fair transition to climate neutrality are increased.

3.Stakeholders, including social partners and civil society, and policymakers are provided with evidence-based knowledge, tools and innovative solutions, which contribute to new policies and strategies for strengthening resilience, fairness, inclusiveness and social cohesion at European, national and regional level.

Scope: Europe is undergoing critical social transformations driven by macro drivers of change, such as climate change, biodiversity loss, digitalisation and demographic change, which have been accelerated by events, such as the COVID-19 pandemic and Russia’s war of aggression against Ukraine. These transformations bring challenges and opportunities such as changing skills demands and labour shortages, new digital and intergenerational divides, increasing inequalities and threats to social cohesion, and rising costs of social protection, among others. The magnitude of these social transformations as well as the heterogeneity in welfare systems and labour markets call for combined inter- and transdisciplinary knowledge and resource sharing, and long-term concerted actions, on the basis of a Strategic Research and Innovation Agenda (SRIA).

Proposals for the co-funded Social Transformations and Resilience (STR) partnership should aim at creating a 7-year research and innovation programme 164 which will make use of the potential of SSH to build resilience, ensure fairness and inclusiveness and foster social cohesion in the light of changes in climate, the environment, technology, demography and unexpected shocks. To this end, proposals should pool the necessary financial resources from the participating national (or regional) research programmes, with a view to implementing joint calls for transnational proposals resulting in grants to third parties.

Innovations and scientific results achieved are expected to contribute to reaching EU priorities in the European Pillar of Social Rights, the EU Green Deal, to strengthening the European Research Area (ERA) and the European Education Area (EEA) and to contribute to designing better national, regional and local policies, in line with their respective strategies.

An additional objective is to contribute to the implementation of United Nations Sustainable Development Goals number 1 (No Poverty), 4 (Quality Education), 5 (Gender Equality), 8 (Decent Work and Economic Growth), 10 (Reducing Inequalities), 11 (Sustainable Cities and Communities), 13 (Climate Action), and 16 (Peace, Justice and Strong Institutions).

To achieve these objectives, the partnership is expected to launch annual transnational calls for proposals and additional activities in four interconnected impact areas:

1.Supporting the modernisation of social protection systems and essential services

2.Shaping the future of work

3.Fostering education and skills development

4.Contributing to a fair transition to climate neutrality

The STR partnership is expected to organise activities along the following six operational objectives:

1.Collect data and evidence to measure social transformations, drawing from a variety of qualitative and quantitative methods in the social sciences and humanities, and use these to inform the development of evidence-based public policies and strategies.

2.Promote comparative studies to identify and share best practices and failures at regional, national and EU level.

3.Construct new, innovative ways to connect researchers with policymakers, stakeholders, citizens and social innovators in working together, communicating needs and results.

4.Develop social and individual experimentations at all levels (subnational, national, European) to better understand the impact of social transformations and public policies.

5.Encourage the development of new analytical, methodological and epistemological tools to better understand social transformations and resilience.

6.Build capacity among the R&I community and policymakers to adjust and strengthen social infrastructures and services in light of unexpected shocks.

Proposals should build on the work of ERA-NETs CHANSE, as well as other relevant networks and initiatives, such as HERA and NORFACE, the Trans-Atlantic Platform for Social Sciences and Humanities (T-AP) and the Joint Programming Initiative More Years, Better Lives (JPI MYBL). By bringing together different stakeholders in academia, policymakers, social partners and trade associations, civil society and international organisations, the partnership should create a critical mass of knowledge and resources to implement a long-term SRIA.

The partnership should engage with the following stakeholders: (i) National research funding agencies and ministries in research and higher education; (ii) ministries responsible for labour, social affairs, employment, climate and environment, where possible, as well as other relevant public authorities in the four impact areas; (iii) researchers from the social sciences and humanities and transdisciplinary fields; (iv) social partners, citizens’ organisations and NGOs at local, national and EU level, such as trade unions, employer associations, practitioners and non-profit organisations advocating for the rights of disadvantaged groups; (v) private sector, which may include employment agencies, providers of essential services, social entrepreneurs, and private education institutions.

As the partnership touches upon fundamental aspects of peoples’ lives (work, social protection, education, and a fair green transition), it is instrumental to involve relevant actors, interest groups and potential end-users of the research results in the partnership’s activities. Gender and intersectional aspects should be considered throughout all activities and joint calls.

EU agencies (e.g. Eurofound, ELA, CEDEFOP 165 ) which deal with issues related to the four impact areas, such as working conditions, vocational education and training, and labour law, as well as international organisations such as the ILO and the OECD, need to be considered as stakeholders, as they can provide important inputs and resources to the partnership. Collaboration with existing research infrastructures (e.g. European Social Survey, SHARE, CLARIN, CESSDA, Eurostat) is encouraged. This should aim at facilitating access to data (e.g. on social security) and making use of relevant datasets in the projects that will be funded under this partnership.

The partnership is open to all EU Member States and countries associated to Horizon Europe and will remain open to third countries wishing to join. Partners are expected to contribute financially and/or through eligible activities 166 , depending on the level of ambition of the proposed activities. The partnership should be open to new partners throughout its lifetime. Importantly, the EU contribution will not be increased.

To ensure coherence and complementarity of activities and leverage knowledge and joint activities, the partnership is expected to establish synergies with relevant Horizon Europe projects under relevant Clusters of Pillar II, partnerships - such as the Driving Urban Transitions (DUT) partnership or the Clean Energy Transition (CET) partnership, the Biodiversa+ partnership, the Missions - such as the Mission on climate-neutral and smart cities or the Mission on Climate Adaptation - and the New European Bauhaus Facility, among others.

HORIZON-CL2-2026-01-TRANSFO-02: Open topic: Strengthen Europe's social model and sustainable competitiveness through productivity

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 167 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.The concept of sustainable competitiveness is analysed taking into account the shifts in geopolitics, global trade patterns, as well as changes in climate, the environment (including biodiversity loss 168 ), technology and demography.

2.Policymakers are provided with recommendations and innovative solutions, including a toolbox to boost Member States and Associated Countries (labour) productivity while ensuring high social and environmental standards and increasing competitiveness within planetary boundaries.

Scope: The Future of European competitiveness report (also known as the Draghi report) 169 analysed and discussed the reason for European declining competitiveness, productivity and growth vis-a-vis its main competitors. A competitive economy is defined as an economy whose sustained rate of productivity is able to drive growth and, consequently, income and welfare. Both the economy and the European social model have to adapt to the great drivers of change, including demography, technology, global trade patterns, climate, and geopolitical shifts.

From its side, the European social model is the basis of the still high level of productivity and competitiveness in the EU, and without continuously upgrading it and sustaining it, there is a risk of a series of negative consequences, ranging from an increase in poverty, to a deterioration of human capital and a decline in well-being.

Research (including by SSH disciplines) carried out should lead to recommendations to help Europe remain a world power through a high level of welfare, competitiveness and productivity, while analysing the tensions and opportunities created by the strengthening of the European social model and sustainable competitiveness through productivity. Proposals should look into possible opportunities and tensions between driving competitiveness, maintaining Europe’s social model and high environmental and biodiversity standards.

Clustering and cooperation among selected projects under this call topic and collaboration with the Social Transformations and Resilience partnership are strongly encouraged.

HORIZON-CL2-2026-01-TRANSFO-03: Tackling child poverty and ensuring disadvantaged children's access to Early Childhood Education and Care

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 170 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Policymakers gain insights into the cost of child poverty and the returns from securing access of disadvantaged children to quality Early Childhood Education and Care (ECEC) in the EU.

2.Policymakers receive operational advice on ways to reduce this cost and support participation of disadvantaged children in quality ECEC to close the gap with other children in the EU.

Scope: Past studies researched the cost of child poverty, and the returns yielded by and ways to secure disadvantaged children’s participation to ECEC, yet their relevance to the current EU context is limited (i.e. most of them were conducted outside of the EU or they are now outdated). Producing EU-specific insights on these issues is the aim of this topic, which should help close the ECEC participation gap and improve social outcomes, in line with the European Pillar of Social Rights, while fostering fiscal sustainability and inclusive growth.

The proposals may:

1.Define disadvantaged children, by going beyond monetary aspects of disadvantages, building on the EU’s concept of risk of poverty or social exclusion, and taking into account systemically marginalised groups.

2.Estimate the cost of child poverty and the returns yielded by participation to quality ECEC by taking into account:

1.children’s needs and effective benefits targeting them,

2.the short and longer-term costs/returns,

3.the economic, social, wellbeing and educational aspects of these costs/returns,

4.children’s, parents’ and aggregate outcomes.

3.Investigate barriers preventing disadvantaged children from accessing quality ECEC.

4.Provide a mapping of the most efficient policies to reduce child poverty cost, comparing ECEC policies’ value for money with other policies.

5.Develop evidence-based and operational policy advice, including ways to better account for these costs/returns in policymaking and good (established or innovative) practices to close the ECEC participation gap. Scalability of these practices may be addressed.

6.Use research methodologies of relevance (qualitative and quantitative, including experimental ones), building on multidisciplinary insights (including from SSH disciplines), and either make use of existing datasets (including administrative datasets), or collect new data. Experts by experience (i.e. vulnerable children and parents) may be involved.

HORIZON-CL2-2026-01-TRANSFO-04: The impact of the use of digital tools outside school and for communication on educational outcomes and mental health

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 171 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Provide policymakers, education practitioners and citizens with a solid understanding of how social media, video gaming and other leisure uses of digital tools relate to the educational outcomes of young people, including through their impact on well-being and mental health.

2.Generate rigorous, policy-relevant evidence about policies and practices aiming to inform and regulate young people’s use of digital tools for non-educational purposes, such as smartphones, at school.

3.Develop actionable advice for policymakers and citizens about how to promote young people’s healthy use of digital tools for leisure, both at school and outside school.

4.Describe and quantify the relationships of using digital tools for leisure and communication with students’ motivation, study habits, attention span and concentration, time management, engagement, social integration and overall well-being.

Scope: The increasing prevalence of digital devices in young people’s life has raised concerns about the potential impacts of the use of digital tools for leisure and communication on primary-, secondary- and higher education students’ well-being and educational outcomes 172 . “Digital distraction” is emerging inter alia as a potential threat to academic performance and several countries have started to regulate the use of smartphones at school.

There is still limited evidence on the interrelation between the use of digital tools for leisure in-school or out-of-school and educational performance, in both primary and secondary education, because most of the existing literature is purely correlational, or only focuses on effects on well-being. Moreover, most existing research is from extra-EU contexts, which may limit the transferability of findings to EU education and training systems.

Several interrelated research questions remain to be addressed, such as:

1.Which types of digital device use do pupils perform during school and do their digital activities differ depending on different contexts (i.e., during class, during breaks or between classes)?

2.How do different activities (e.g. playing games vs. chatting with a parent), on different devices, with different time durations of use, relate to students’ attention span and concentration as well as general school motivation?

3.How does frequent smartphone, social media use and other online leisure activities (such as video games) impact students’ attention span, concentration, memory and relational capacities?

4. 

5.How can schools, educators and parents balance the use of those tools to enhance, rather than hinder, educational performance and students’ well-being?

6.What is the potential for addiction when using digital tools and what are the decisive factors for this on the part of the design of tools on the one hand and on the part of the users on the other?

7.How can digital leisure activities contribute to skills development, such as problem-solving and digital literacy and what is the transferability of these skills into education? How do these benefits compare with potential harm?

8.What is the role of parents and educators in guiding digital leisure activities? Explore parental digital literacy and its impact on the use of digital devices by the youth.

Proposals should explore the complex, context-dependent ways in which different forms of digital leisure affect attention, motivation, creativity, learning habits, critical thinking, and socio-emotional skills. They should consider variations across age groups, socio-economic backgrounds, cultural contexts, and types of digital engagement and include students with disabilities.

Proposals should apply rigorous experimental and/or quasi-experimental methods for their analysis and could complement them with experience sampling research, survey research methods and qualitative research methods. Close cooperation with educational authorities, educational institutions and educators in analysing existing policies and practices is essential. Proposals should also include the opinions of young people and other relevant stakeholders, such as media literacy organisations, for example, in the form surveys, interviews, consultations, as part of the data collection. Proposals could apply interdisciplinary approaches (including from SSH disciplines), combining insights from economics, sociology, neurosciences, communication science (media psychology) and pedagogy. Clustering and cooperation with other selected projects under this call and other relevant projects are strongly encouraged.

HORIZON-CL2-2026-01-TRANSFO-05: Contribution of basic skills to productivity, innovation, competitiveness and economic growth

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 173 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Provide policymakers with a more detailed understanding of the contribution of basic skills on the economy in the short and medium term, with a focus on their contribution to productivity and innovation, to sustain EU competitiveness and growth.

2.Develop actionable advice about how, in a lifelong perspective, education and training systems can help foster basic skills.

3.Promote productivity, innovation, competitiveness and growth, including by reducing gender, disability and socioeconomic gaps in basic skills.

Scope: In the context of the Union of Skills, the 2025 European Commission’s Action Plan on Basic Skills identifies five basic skills: literacy, mathematics (including also financial literacy), science, digital and citizenship. Strong basic skill levels among young people and adults are key to sustaining EU productivity, innovation, competitiveness and growth, as also explained in the 2024 Draghi Report 174 . Other key EU initiatives support lifelong learning as a driver for productivity, innovation, and economic growth, for instance the 2022 Council Recommendation encouraging the implementation of Individual Learning Accounts (ILAs) in Member States.

Evidence of causal relationship between basic skills on the one hand and productivity, innovation, competitiveness and economic growth, on the other is still limited in Europe, both at microeconomic and macroeconomic levels, mostly due to scarce use of longitudinal data. This also applies to the interplay between the basic skills and other skills (such as socio-emotional skills) in promoting productivity, innovation, competitiveness and growth.

There is also a need for better evidence (including from SSH disciplines) on which education and training policies and practices at all levels (school education, vocational education and training, higher education, adult education) can be effective in reducing gender, disability and socioeconomic disparities in basic skill acquisition and in subsequent labour market outcomes. The research should also better explore the competences that learners need to learn effectively with AI-based tools. Additional evidence is required on how to increase female participation in STEM and how to address teacher shortages, as well as on how to address barriers faced by persons with disabilities.

Proposals should address those research gaps by applying rigorous quantitative methods with a longitudinal perspective for their analysis and could complement them with qualitative research methods. Proposals should also evaluate the inclusion aspect, and the costs associated with the policies or practices analysed. Cooperation with education and training stakeholders is encouraged. Clustering and cooperation with other selected projects under the call HORIZON-CL2-2024-TRANSFORMATIONS-01-10: “Effective education and labour market transitions of young people” and other relevant projects, as well as the Social Transformations and Resilience Partnership are strongly encouraged.

HORIZON-CL2-2026-01-TRANSFO-06: Making Europe a global magnet for talent - Attracting and retaining students, researchers and high-skilled workers from outside the EU

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 3.30 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 10.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 175 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Generate rigorous, policy-relevant evidence on the factors that may influence students, researchers, and high-skilled workers from non-EU countries to move to and remain in the EU.

2.Provide policymakers and higher education/research institutions with guidance on which policies and programmes could be effective in attracting talented students, researchers and high-skilled workers from non-EU countries to the EU.

3.Develop actionable advice to policymakers and higher education/research institutions about how to retain talented students, researchers and high-skilled workers from non-EU countries to ensure a long-term positive impact on the EU economy’s innovation and competitiveness.

4.Provide evidence-based policy insights/options to improve the coherence of migration pathways for skilled talent across the EU. Support the development of more flexible and attractive mobility schemes, reducing administrative barriers, increasing accessibility and enhancing retention mechanisms to enhance the EU’s competitiveness in research, innovation, and cultural exchange.

Scope: The EU’s ability to compete on a global scale depends not only on retaining homegrown talent but also on actively drawing and retaining talent from outside Europe. The Union of Skills, adopted in March 2025, aims to make the EU and the European Research Area (ERA) a global magnet for talent, to attract and retain brilliant extra-EU tertiary students, top-level researchers and high-skilled workers. There is still limited research on what specific factors and their variability across Member States and Associated Countries (e.g. academic quality, career opportunities, cultural appeal, political context or funding availability) most influence the decision-making process for international students when choosing destinations. The same applies to the factors that can make a destination desirable for researchers and other high-skilled workers (e.g. quality of life, wages, professional opportunities, integration and family reunification measures, support to innovation ecosystem). More evidence is also needed about:

1.How policies and programmes can be successful in retaining students, researchers and high-skilled workers from abroad into the EU (and into Horizon Europe Associated Countries) in the medium-to-long term. Projects should assess the functioning of Talent Partnerships.

2.How to mobilise the professional potential of humanitarian migrants already in the EU in the context of global competition for talent.

Proposals should apply rigorous quantitative methods for their analysis of the abovementioned factors, policies and programmes and could complement them with qualitative research methods and relevant research from SSH disciplines. Proposals should also address the gender and disability dimensions of attracting and retaining talent. As the pull factors may differ among categories of migrants, proposals can choose which group to focus on: students, researchers and/or high-skilled workers.

Cooperation with higher education institutions, research institutions, non-academic organisations and notably industry, and social partners, as well as clustering and cooperation among selected projects under this call and other relevant projects, are strongly encouraged.

HORIZON-CL2-2026-01-TRANSFO-07: Fostering competences for the green transition

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 176 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Provide policymakers, education and training institutions, and social partners with a solid understanding of which competences young people and workers need to support the EU economy towards the green transition to reach carbon neutrality and protect natural ecosystems.

2.Develop actionable advice to policymakers and education and training institutions about which education and training programmes and policy measures can promote the acquisition of those competences by young people and workers in a lifelong perspective, including the gender and disability dimensions.

3.Provide policymakers with guidance on how to address the interconnection between fostering the competences for the green transition and those for the digital transition.

Scope: Environmental challenges have been one of the key drivers of labour demand and skills supply across all sectors for the past years. More data and analysis from research on competences that young people and workers need for the green transition are warranted to properly implement the Union of Skills and support people in upskilling and reskilling. The availability of robust quantitative data is still limited, both at national and international levels. Moreover, most available research on the green transition focuses on macro-level policies, overlooking how workers and communities can drive change.

Fostering competences for the green transition also requires a better understanding of young people’s and workers’ attitudes, concerns and behaviours about climate change and climate action, biodiversity loss, pollution, circular economy and sustainable economic growth, as well as of new ways of developing capabilities and skills 177 . The transferability of skills across occupations and the need for upskilling and reskilling the current workforce are also key to advancing the green transition. These issues are interconnected with the ongoing digital transition.

The ‘green transition’ embraces a wide and diverse set of sectors and activities without one specific set of generic competences (in other words skills vary strongly depending on the sector). For example, according to Cedefop 178 , among high climate impact sectors the demand for skills for the green transition is the highest in energy. Therefore, proposals should focus on one of the following sectors, which are particularly affected by an increasing demand for green expertise: 1) sustainable agriculture and food production, 2) automotive industry, 3) energy and 4) construction, 5) nature and climate adaptation.

Proposals should use quantitative and qualitative methods (including from SSH disciplines) and apply a lifelong perspective to address several research questions, such as:

1.What are the most relevant competences required to actively contribute to the green transition in these industries?

2.Which assessment methods and frameworks are most effective in measuring readiness for green jobs and sustainable innovation?

3.What roles do digital skills and technological literacy play in equipping young people and workers for the green transition and how can education and training systems exploit the synergies between the competences for the green and digital transitions?

4.How can policymakers, education and training institutions and employers collaborate to identify and address skills shortages that may hinder the green transition?

5.How can vocational education and training systems become more accessible and flexible to respond effectively to evolving labour market needs for the green transition?

6.How to ensure that women and persons with disabilities benefit equally from the opportunities of the green transition?

7.How does an effective lifelong acquisition of competences for the green transition occur?

8. How can we design and implement inclusive systems that improve career advice, and support the best decisions by all learners regarding t their career choices and pathways?

9.What works to get disadvantaged children onto the pathways that are proven to lead to upwards mobility (including helping those who are not in education, employment or training) and raising ambition where needed? At what age are interventions most effective?

10.How can policymakers best create collaborations with industry to increase training opportunities, to ensure learners are as prepared as much as possible for work, and to reduce barriers to those from disadvantaged backgrounds?

Proposals should also consider the gender and disability dimensions in their analysis (ensuring that women, as well as persons with disability, benefit equally from employment and earning opportunities linked to the green transition). Clustering and cooperation among selected projects under this call topic and other relevant projects, for example from the Horizon 2020 European Green Deal Call and their results, are strongly encouraged.

Proposals should also explore synergies with the New European Bauhaus (NEB) Facility, including notably the NEB Academy on skills for sustainable construction, and the European Partnership on Social Transformations and Resilience.

HORIZON-CL2-2026-01-TRANSFO-08: Strengthened implementation of the EU Pact on Migration and Asylum and a focus on inclusion, integration, and health

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 179 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to either the first and second (combined), or the third and fourth (combined) of the following expected outcomes:

1.Improved implementation of the EU Pact on Migration and Asylum through evidence-based insights in asylum and migration management, age assessment of minors, and resettlement frameworks, ensuring fair and efficient migration governance.

2.Insight into legal pathways addressing both EU Member States’ needs and potential offers of circular and permanent migration schemes in selected partner countries.

3.Enhanced health equity for migrants, including refugees by integrating robust health data into national systems, addressing governance barriers, and tackling intersectional inequities in healthcare access, identifying data/indicators on basic needs in health and sanitation, including as compared to adequate treatment.

4.Comprehensive evaluation of long-term social inclusion and integration strategies, providing evidence-based policy recommendations for labour market access, housing, education, health (including mental health), recognition of qualifications and validation of skills, youth participation, and social, political, and cultural inclusion.

Proposals should state clearly which expected outcomes their proposed research will contribute to.

Scope: The EU Pact on Migration and Asylum 180 has introduced several key mechanisms requiring robust evidence to support their effective implementation. Proposals should conduct a comprehensive analysis of the Pact’s components, including, for instance, the solidarity mechanism, the age assessment framework for minors, crisis and force majeure migration management, the EU externalisation policies on global migration patterns and the Union Resettlement and Humanitarian Admission Framework. This analysis should account for diverse national institutional landscapes and propose tailored policy recommendations that uphold human rights and enhance practical implementation.

The landscape of health data concerning migrants, including refugees is fragmented, incomplete, and often of low quality. This situation is compound by political, governance, legal and structural aspects that challenge the effective integration and utilisation of available data.

Proposals should map the existing landscape of health data integration for migrants, including refugees across national health information systems, evaluating existing data collection frameworks, methodologies, and technologies used to gather and integrate health information on migrant populations, highlighting potential systemic and organisational barriers. They should identify challenges and best practices that have successfully facilitated data integration while maintain high standard of data privacy and security and provide policy recommendations.

Moreover, there is a lack of research exploring how intersecting factors such as age, gender, disability and legal status influence health outcomes among migrant and refugee populations, including older migrants. Addressing these gaps (including through a contribution of SSH disciplines) is essential for the development of informed policies that ensure equitable health care access and improve overall health outcomes with special consideration to persons in a vulnerable situation. Proposals should incorporate analysis of the impact of intersectional factors in access to health for migrant and refugees' populations.

Beyond health, understanding the long-term impact of social inclusion and integration 181 strategies, is critical. Proposals should develop comprehensive and comparative evaluation frameworks to measure the effectiveness of existing strategies at the EU, national and local levels, identifying best practices at all levels (EU, national, local) and particularly the role of small and medium-sized towns; municipalities and recommending innovative policy adjustments. Areas of focus should include labour market access, mobility options of asylum seekers within the Dublin framework, housing, youth and women participation, the contribution of private sector and non-state actors and the broader social, political, and cultural inclusion of migrants, including refugee communities, including the role of education, as well as linguistic competence in the language of the receiving country. Proposals are encouraged to explore the biographical dimensions of integration, acknowledging the personal trajectories of migrants, including refugees. Research should also explore the relationship between migratory movements and social identity formation, ensuring that integration policies are adaptable to evolving societal dynamics and sustainable over time. Proposals should incorporate quantitative data and sound methodologies to identify effective practices, target groups, and enabling conditions to assess integration policies and in particular labour market integration outcomes. Wherever relevant proposals are encouraged to include migrants and/or refugees as participants in their research assessing first-hand their experiences, needs, attitudes and opinions.

Proposals may envisage JRC participation, drawing on its cross-cutting expertise in migration governance, social inclusion, and integration including from a health aspect. The JRC could, for example, contribute to comparative policy analysis, harmonised data collection across Member States, and evidence-based support to EU-level decision-making, utilising its experience in modelling policy mechanisms, analysing data and developing indicators, analysing inequalities, and providing forecasting and foresight on migration trends.

Where relevant, proposals may consider citizen engagement and dialogue beyond migrants, including refugees, with a view to collecting broader input.

HORIZON-CL2-2026-01-TRANSFO-09: Rethinking long-term care policy in the face of EU demographic shifts

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.75 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 15.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 182 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Evaluate the effectiveness and resilience of existing long term-care (LTC) policies at national and regional levels.

2.Provide policy makers with scientific knowledge and data for evidence-informed policies to address the rising demand for affordable, accessible and high-quality long-term care, with the focus on efficient use of resources, including human, financial and technological.

3.Propose new policy solutions to address rising long-term care needs and to ensure smooth (in)formal care transitions, including from the perspective of active and healthy ageing policies and the development of integrated care service provision at local level.

Scope: In the EU, the number of people with long-term care needs is projected to increase in the future. In 2070, this number is expected to be 21% higher than in 2020.This increase is largely due to the acceleration of population ageing and also relates to higher needs for palliative care. At the same time, many Member States already struggle to meet all the long-term care needs now due to workforce shortages, which are likely to aggravate in future as the long-term care workforce is itself ageing and the sector is not attractive due to difficult working conditions, limited career development pathways and low professional standards.

Scientific evidence from research and innovation (including from SSH disciplines) is needed to help address the increasing demand for long-term care in the EU in the context of shrinking labour resources and increasing pressures on public and private budgets.

In line with the European Care Strategy and complementing the activities of the European Partnership on Transforming Health and Care Systems 183 , proposals should:

1.evaluate the effectiveness of existing national/regional long-term care policies in terms of meeting the current long-term care needs through sufficient and adequately skilled long-term care workers, making formal long-term care affordable, accessible and of high quality; in that respect, evaluate the role of integrated care and the interplay of long-term care and other social services;

2.develop robust methodologies to model projections until 2070, for long-term care needs and supply including in terms of workforce and types of services, and corresponding public funding needs for at least 15 EU Member States; quantify the cost of non-action in terms of impact on unmet LTC needs, health and well-being outcomes, and missed opportunities for economic returns;

3.identify and analyse innovative policy mixes, including based on social innovation, to address long-term care needs and long-term care supply challenges, with available and/or new public/private resources, including by tapping into the potential of digitalisation and new technologies. Aspects for consideration may include addressing workforce and skills shortages by increasing the attractiveness of the long-term care sector through improved working conditions and social protection of the long-term care workforce; the deployment of digital solutions including AI-based; investigating the cost-effectiveness in the use of public budgets for health and social care and the role of private funding in the sector.

Applicants are encouraged to consider the data offered by European Research Infrastructures in the social sciences domain, 184 as well as the body of LTC policy analysis developed by the European Commission 185 . Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud (EOSC), as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

Applicants aiming to address the implications of demographic changes on health and care systems should check in advance which areas are covered by the Transforming Health and Care Systems partnership and what research the partnership is performing to avoid a duplication of efforts or potential double funding.

Proposals should consider the involvement of the European Commission's Joint Research Centre (JRC) 186 based on its experience and with respect to the value it could bring in providing an effective interface between research activities and policymaking.

Proposals should integrate a gender-sensitive and intersectional approach to address the diverse long-term care policy needs of care-recipients and caregivers.

To maximise impact and avoid unnecessary duplication, proposals should envisage, as appropriate, cooperation with Horizon Europe projects such as the ones funded by the call topic HORIZON-CL2-2022-TRANSFORMATIONS-01-10, “Socio-economic effects of ageing societies” 187 and the HORIZON-CL2-2023-TRANSFORMATIONS-01-08 call topic entitled “Integrated care solutions leading to better quality, person-centred long-term 188 .

HORIZON-CL2-2026-01-TRANSFO-10: Fostering cooperation and integration between SSH and STEM research and innovation in the EU

Call: Culture, Creativity and Inclusive Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.50 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 189 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Greater integration of SSH and STEM 190 research and innovation in R&I initiatives funded at EU level, national and/or regional level, as well as in R&I policies by promoting dialogue, mutual learning and strategic cooperation among research funders and policy makers in the EU.

2.Developing and maintaining a new, common, comprehensive ‘Monitoring and Impact Evaluation Framework’ for SSH integration in current and future EU R&I initiatives.

Enhanced facilitation of knowledge exploitation and support to the cooperation between projects and stakeholders, as well as R&I policies involved in projects and other types of cross-border networks dealing with SSH and STEM research and innovation.

Scope: As mentioned in the Report ‘Align, Act, Accelerate: Research, Technology and Innovation to boost European Competitiveness’ 191 , European RD&I can provide a new understanding of and solutions to tackle societal challenges. Social sciences and humanities (SSH) and Science, Technology, Engineering and Maths (STEM) improve the research activities, outcomes and impacts of Horizon Europe, because they enable a greater understanding of societal and competitiveness benefits. The cooperation of SSH and STEM in through trans- and interdisciplinary science is part of a science that is excellent, as it not only delivers excellence in the technical aspects, but also in taking account different societal needs. Thus, there is need for a leading role at European level for this cooperation.

Proposals are expected to create an SSH-STEM Action, that focusses on SSH-STEM monitoring, SSH-STEM facilitation and SSH-STEM promotion, at European level, which should also include all the following aspects:

1. Monitoring:

Monitoring is a major aspect of the essential activities 192 .

The action should create a new strategy in the first year of the project with the aim to develop and to monitor the SSH-STEM research cooperation (e.g. A.I. search tools). This monitoring strategy should meet the following requirements:

1.Applicants should provide a clear justification of what significant steps forward they propose regarding methodology compared to previous reporting on SSH-STEM collaboration (see relevant reports), data management, analytical methods, data collection. Robust open data driven approaches are strongly encouraged.

2.Applicants should describe what steps they will undertake to ensure the delivery of reporting on a yearly basis, which should include the data collection, data analysis, and interpretation of SSH-STEM related cooperation data (in EU-funded projects in Horizon Europe where there is SSH-STEM cooperation).

2. Facilitation and promotion:

Applicants should develop guidelines for SSH-STEM cooperation and support stakeholders in their projects when SSH-STEM cooperation is possible within the project, with a focus on increasing the quality and depth of cooperation and applying cooperation where most relevant. Applicants are encouraged to propose approaches, such as training to researchers on how to best integrate either STEM or SSH into their research. In addition, applicants should take into account the collaboration within SSH sciences on their own, as well as attention for not only quantitative SSH disciplines, but also qualitative SSH.

The action should organize an annual event showcasing SSH and STEM cooperation; with exchanges with / for policy makers, best practice examples and showcasing funded projects/ programs at EU, national and other levels.

The action is also expected to provide a quantitative and qualitative R&D evidence base on how to ensure that policies (including funding) aimed at stimulating research & innovation are appropriate for the sectors which have the greatest potential to contribute to Europe’s competitiveness. Applicants should propose evaluation metrics for SSH-STEM cooperation within research projects.

3. SSH/ STEM Science for Policy:

An important part of promotion is that the action acts as an SSH/ Science for policy exchange as well, providing the European Commission with feedback and advice on SSH-STEM cooperation, and informing the European Commission of the latest developments in SSH-STEM cooperation (which is why the inclusion of SSH experts is of the upmost importance).

The action is expected to be a forum that promotes dialogue and cooperation among research funders and policy makers in the EU (linked to the European Research Area) and beyond to further the integration of SSH and STEM in EU-funded R&I initiatives.

The action should provide monitoring guidance in SSH and STEM cooperation in R&I programmes at national/regional and European level.

The consortium should contribute to the priorities of the European Research Area, the EU Competitiveness Compass to strengthen the EU competitiveness and resilience. The consortium is expected to liaise with the two Cluster 2 co-funded European Partnerships and look into successful SSH integration projects and initiatives funded at EU level.

The action should recognize the diversity within SSH disciplines and their differing levels of integration with STEM. It should include targeted strategies to increase humanities’ participation alongside qualitative and quantitative social sciences to ensure balanced SSH representation. STEM domain prioritization should be driven by thematic relevance and feasibility for SSH cooperation.

Projects should adopt a gender-sensitive and intersectional approach when integrating SSH and STEM. This means considering a variety of societal needs and perspectives to ensure inclusivity and equality in research and innovation in EU and national R&I policies.

HORIZON-CL2-2027-01-TRANSFO-01: Impact of access to nature-positive environments in promoting social cohesion and reducing inequalities in urban and peri-urban settings

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 193 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Policymakers and civil society organisations will have robust evidence on whether inclusive management of (peri-)urban environmental commons fosters climate and societal resilience, social inclusion, wellbeing and community participation, and whether lack of access to biodiverse green and/or blue spaces exacerbates existing social inequalities (e.g. poverty, marginalisation, and low community wellbeing among vulnerable groups) and people’s sense of inequality and insecurity.

2.Development of strategies and innovative solutions to quantify and integrate the distributional aspects of access to quality green and/or blue spaces into integrated spatial planning, accounting for non-market values when making decisions about long-term land use and (peri-) urban development with the aim of supporting nature restoration/preservation in the face of competing pressures and on-going change both in Europe and outside, while achieving a fair and equitable relationship between social groups and the environment.

Scope: Proposals should focus on exploring and better understanding the relationships between access to quality green and/or blue spaces in the pursuit of social and environmental justice, community cohesion and overall social fabric. Proposals may also look at how to support fair transitions to climate-resilient communities from a climate adaptation and biodiversity perspective, ensuring a link to cohesion and social resilience. Targets, notably for urban ecosystem restoration, under the EU Nature Restoration Regulation 194 should be taken into account. Synergies with the EU Urban Agenda may also be considered.

Research to date has largely focused on the benefits of nature on individuals (e.g., improved health, reduced stress), while more and up-to-date knowledge is needed on their effects at a societal level and across cultural, geographical and socioeconomic contexts as well as the range of functional needs of different groups.

This topic aims to bridge the knowledge gaps surrounding a fair and equitable relationship between social groups and the environment, in particular the link between nature-as a public good and its role in fostering civic engagement that cultivates social cohesion, community wellbeing, shared identity and sense of belonging and place-making.

Studies show that disadvantaged communities have fewer and lower-quality green and/or blue spaces, but less is known about the mechanisms through which access to nature-positive spaces strengthens cultural identities (at the individual and group levels), cohesion and resilience, particularly in lower-income communities and across generations.

Proposals may explore:

1.The community-level impacts of initiatives aiming to introduce green and/or blue spaces and an understanding of how intentional design and planning can help improve societal outcomes throughout the community, with special attention to how socially vulnerable groups may be impacted, which types of natural spaces are used for which activities and what distance constitutes 'accessible' or sufficient to promote social contact. When considering the notion of access to quality green and blue spaces, researchers should consider not only the physical distance to these spaces, but other barriers such as the state of desolation of public green and/or blue spaces, privatisation, as well as cultural, social, economic barriers to access nature.

2.Knowledge gaps around the long-term impacts of lack of access to quality green and/or blue spaces, and how this amplifies existing socioeconomic inequalities, in particular the intersection with other determining factors of sociopsychological and mental wellbeing such as age, education, employment, housing, health, mobility and socioeconomic status, including aspects around ease of access, affordability and capacity to empower communities, particularly among vulnerable groups (such as marginalised urban communities, including migrants and informal settlements).

3.The role that community-based projects – for example those aimed at social participation and inclusion, environmental preservation, circular economy and food security, and preserving natural heritage (e.g., urban gardening, traditional ecological knowledge practices, rewilding, nature conservation, nature-based solutions and citizen science) – play in strengthening community agency, identity, place attachment, and sociopsychological, mental and material well-being and social capital.

4.The role of green and/or blue spaces in the mitigation of inequalities in pollution exposure, a source of concern in many disadvantaged communities.

5.The potential contributions of local businesses and social economy actors to the implementation of green and/or blue spaces, as well as the meaningful participation of individuals, representing different economic/labour sectors and collective identities within the community.

6.The contribution of nature to place-making and the ways in which approaches from the arts and humanities can contribute to how we understand place, and shape future places, in concert with local communities.

Proposals are expected to adopt a gender-sensitive and intersectional approach to analyse differential access to nature-positive environments across population groups. Particular attention should be paid to identifying the structural and systemic drivers of these disparities, as well as assessing the social, economic and health-related impacts of unequal access on individuals and communities.

Interdisciplinary approaches (including from SSH disciplines), combining insights from sociology, anthropology, law, environmental philosophy and systems science, are encouraged. Clustering and cooperation with other selected projects under this and past calls are strongly encouraged, in particular topic HORIZON-CL6-2025-01-BIODIV-06: ‘Assessing and modelling socio-economic impacts of nature restoration’, topic HORIZON-CL6-2023-COMMUNITIES-01-1: ‘Enhancing social inclusion in rural areas: focus on people in a vulnerable situation and social economy’ and topics under the New European Bauhaus (topic HORIZON-NEB-2026-01-PARTICIPATION-03: Understanding inhabitant’s experiences of neighbourhoods to support their health and well-being, and topic HORIZON-MISS-2027-07-CLIMA-CIT-NEB-01: Urban nature: supporting restoration of urban ecosystems, along urban transport networks and in the built environment). Participation by entities from cities that are signatories of the Green City Accord 195  is encouraged. Proposals should engage civil society organisations in the development of their actions.

HORIZON-CL2-2027-01-TRANSFO-02: Impact of in-kind benefits on income distribution and on vulnerable populations

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 3.30 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 10.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 196 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Policy makers get a mapping of in-kind benefits across Member States and a comprehensive measurement framework.

2.Policy makers gain insights on the availability of in-kind services, on potential gaps in their provision, and on reasons for non-take up.

3.Policy makers gain insights into the redistributive role of in-kind benefits and on the segregation of different social groups, through SSH research.

4.Policy makers receive operational advice to make informed policy choices which reduce inequality and strengthen fairness and cohesion.

Scope: In-kind benefits refer to non-cash goods and services provided to individuals or households, typically by the government (national, regional and/or local), to support their well-being or fulfil basic needs. Unlike cash transfers, which can be spent at the recipient's discretion, in-kind benefits ensure that resources are used for specific purposes for free or at a subsidised cost (e.g. food banks, social housing, health and long-term care services, childcare, schooling, sport infrastructure, public transport). Despite the wide range of in-kind benefits, there is poor empirical knowledge basis of the impact of in-kind benefits (except for healthcare) on the income distribution and on vulnerable groups, unlike the impact of cash benefits.

Research activities may focus, as a baseline, on establishing a full mapping of in-kind benefits (both for free and at a subsidised cost, universal and means-tested) provided by national, regional and local governments. This mapping, potentially structured along the life-cycle perspective and/or around specific groups, might help to develop EU indicators on in-kind benefits and improve comparability.

Proposals may develop a comprehensive measurement framework based on methods, tools, available data and indicators, both qualitative and quantitative and both ex ante and ex post. The framework may translate in-kind benefits into income and show their redistributive role (on income groups, vulnerable populations, marginal and/or small size groups) and ensure cross-country comparability.

Proposals may consider identifying the availability of in-kind benefits at local level, potential gaps, take-up rates for in-kind benefits and their reasons (e.g. capacities' incompatibility with the local needs). They may involve vulnerable communities in the evaluation design.

Proposals may provide operational advice to policy makers on how to translate the research results into concrete actions to reduce inequality and strengthen fairness and cohesion.

The overall aim is to close the knowledge gap covering various dimensions. Therefore, it is expected that proposals apply a gender-sensitive and intersectional approach, including age, to their research.

HORIZON-CL2-2027-01-TRANSFO-03: Rethinking sustainable competitiveness beyond traditional perspectives: role and contribution of the Social Economy

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 197 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Social enterprises, traditional firms and investors will benefit from a better understanding of the sustainable competitiveness factors of the social economy 198 in Europe through knowledge development and know-how on innovative products and services, improving quality and productivity, and increasing adaptability, social inclusion and sustainable, environmentally friendly (for example biodiversity-enhancing) practices.

2.Citizens and traditional private sector will benefit from the increased contribution of the social economy to the EU’s sustainable competitiveness and shared prosperity goals. The research will inform policy makers and private sector on best practice, policy and regulatory reforms aimed at enhancing the social economy's contribution to the EU's competitiveness and prosperity goals.

3.The social economy's principles for sustainable competitiveness are promoted, through the development of practical and innovative solutions.

Scope: The European Union is committed to fostering a social market economy that promotes sustainable growth, social justice, and economic competitiveness. In this context, the social economy has emerged as a potential driver of innovation, job creation, and social inclusion. On the other hand, there is still a persistent knowledge gap in the literature when it comes to appreciate the multifaceted contribution social economy actors make in shaping and advancing economic competitiveness within and across the EU society and its impact on inclusive wellbeing and the environment (for example, the prevention of environmental degradation or loss of biodiversity 199 ).

Sustainable competitiveness and shared prosperity are key a political priority of the new European Commission 200 . In this context, the notion of sustainable competitiveness is less about relative labour cost and more about skills, innovation, entrepreneurship and adaptation. It focuses on the ability for an individual, a firm, a sector, or a country to increase shared prosperity in relation to the current and future environment and society.

The link between social economy and sustainable competitiveness relies on innovation, which needs to be made broader, going beyond “mere” technological innovation and embrace social or even better societal innovation.

Proposals should focus on exploring the potential virtuous relationships between social economy, sustainable competitiveness and shared prosperity.

Research (including from SSH disciplines) should focus on a deeper understanding of the factors contributing to the sustainable competitiveness of social economy entities on one side and, on the other, its possible impact on EU sustainable competitiveness. This requires addressing knowledge gaps, such as the lack of a comprehensive framework to measure the social economy's contribution to sustainable competitiveness in the European Union.

Research may undertake a review of existing literature, analysis and develop case studies to identify the key enabling factors that make social economy entities competitive in a sustainable way, while considering the social, economic, and environmental dimensions.

To better capture the role of the social economy as one of the drivers of sustainable competitiveness, the research may develop a framework to measure its contribution including with existing and new indicators and metrics.

Research may identify best practices, develop toolkit and policy recommendations on how social economy in Europe can boost public and private competitiveness linked to EU shared prosperity goals (such as well-being and nature preservation).

The regulatory context and its impact on the social economy's ability to contribute to sustainable competitiveness should be considered.

Activities may involve interdisciplinary research, stakeholder engagement, and policy analysis. Researchers may need to draw on expertise from different fields (economics, sociology, environmental science, public administration) to develop a comprehensive understanding of the social economy's role in promoting sustainable competitiveness, in line with the EU Green Deal and in the Kunming Montreal Agreement..

The scope of this call topic is not limited to any specific sector, value chain or enabling factors, however, proposals may put emphasis on a specific one. Collaboration with stakeholders from the social economy, private sector, and public sector to develop a deeper understanding of the complex relationships between social economy and sustainable competitiveness is encouraged.

HORIZON-CL2-2027-01-TRANSFO-04: The impact of EU labour mobility on the Member States of the EU

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 201 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Policymakers gain insights into the economic and social effects of worker mobility across the EU, including effects on wages, fiscal budgets, and social systems for both sending and receiving regions.

2.The benefits of mobility are maximised through actionable recommendations, which consider challenges such as demographic changes, regional effects, digitalisation and, to a suitable extent, further developments such as the green transition or adaptation to climate change (including its potential impact on the economic development and the attractiveness of regions) or the green transition and discussions around the accession of further countries to the EU and wider geopolitical instabilities.

Scope: While the EU facilitates free movement as one of the four freedoms of the single market, the long-term social and economic dynamics and implications for both receiving and, especially, sending regions remain underexplored. These include not only direct effects on fiscal and social budgets but also more subtle impacts, such as on the networks, skills, and experiences that individuals bring back to their home regions, but also on the income distribution in the country from which the movers originate.

Gaining a deeper, data-supported understanding of these diverse often complex effects is crucial for shaping policies that effectively harness the benefits of mobility across Europe. In doing so the research shall contribute to the ongoing efforts of strengthening the internal market and make Europe more competitive, while also ensuring social fairness and delivering on the European Pillar of Social Rights, in particular with regard to fair working conditions and ensuring access to adequate income and social protection for all. For the variations across different groups (including - but not limited to - gender, age, level of qualification) could be explored. Harnessing the benefits of mobility is also to be seen in the wider context of the green and digital transitions, necessitating enhanced labour mobility to address skill mismatches and shortages and demographic challenges.

Proposals should build on relevant previous research (including from SSH disciplines), some of which has been conducted in previous Horizon Europe and Horizon 2020 projects 202 . Proposals should have a clear focus. Quantitative approaches and/or econometrics should be part of the proposed methodology. Approaches which can capture developments over time, such as panel analysis, might thereby be of added value.

Projects should analyse the effects of labour mobility on the functioning of social security systems (eventually differentiating between the different pillars of the social security systems, e.g. pension system, health, care, etc.) in countries of origin and destination and their coordination and/or provide research which fosters an informed debate on potential strategies for a future-proof and efficient EU-level social security coordination.

Beyond that, the projects may:

1.Explore ways to improve the quantification of the volume of various forms [e.g. long-term movers, seasonal work and other forms of short-term mobility, postings, cross-border (tele-)work etc] of labour mobility and/or make available figures more comparable across Member States.

2.Develop economic models to assess the EU-level economic effects of labour mobility.

3.Pay attention to the ecological effects of labour mobility and link those with the socio-economic effects.

4.Analyse whether and in which way the composition of movers (e.g. skill-level, age structure, status in labour market, etc.) matters for the socio-economic effects observed in the countries/regions of origin/destination.

5.Provide a comparative analysis of intra-EU labour mobility with labour mobility in other world regions or to geographical mobility within Member States.

6.Develop and test a model to forecast labour mobility in different scenarios (e.g. making assumptions about the economic and social development in different parts of the EU).

7.Take an evidence-based position whether – and in which way - geographical mobility contributes to manage economic change (e.g. whether movers are more willing to work in another sector).

8.Analyse to which extent and under which conditions regions with net-outward mobility have benefited or can benefit – eventually in the longer run – from this mobility.

9.Investigate the economic and social differences between labour migration and labour mobility, the experience with EU enlargement might be used to analyse this.

10.Provide evidence on which policy instruments are most suitable to ensure a labour mobility which is not perceived as unfair (e.g linked to exploitation, social dumping etc.).

These aspects illustrate thematic areas which could contribute to the objective of developing a vision for the future of labour mobility in the European Union and to discuss how legal and institutional frameworks can be adapted to support mobility in a way that is both economically and socially beneficial. This includes modernising the coordination of social security and ensuring that policies reflect the realities of modern society and work arrangements.

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud (EOSC), as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

HORIZON-CL2-2027-01-TRANSFO-05: The effective use of artificial intelligence in learning environments in pre-primary and primary education

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 203 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Provide policymakers and educators and parents with a solid understanding of the potential benefits, opportunities and challenges stemming from the use of artificial intelligence tools in learning environments in pre-primary and primary education, including with regard to their ethical dimension.

2.Generate rigorous, policy-relevant evidence on the impact of use of artificial intelligence tools in learning environments on educational performance and youth well-being.

3.Develop actionable advice to educators about how they can make an effective use of artificial intelligence tools in their work, including for the assessment of learning outcomes.

Scope: The use of artificial intelligence (AI) in learning environments in pre-primary and primary education is rapidly growing. However, there is limited evidence on how AI can challenge and improve learning outcomes, enhance the teaching techniques and support the teaching profession and how automating administrative tasks helps teachers focus on pedagogy and teaching challenges. Most existing research is from extra-EU contexts, which significantly limits the transferability of findings to EU education and training systems and is often conducted on a limited number of participants and covering short-time spans, hindering the possibility of generalising its findings. Moreover, research on the implications of AI tools for equity and inclusion in education is lacking. There is also a need to better investigate the challenges that AI poses to teaching and learning as well as pupils’ well-being. AI is developed to increase human efficiency yet also comes with often unexpected risks and challenges, especially when being applied to child audiences.

The research (including through SSH disciplines) could explore how AI can enhance curricula, improve teaching methods, and personalise learning through adaptive technologies. It should also consider the developmental appropriateness of AI tools for young learners, focusing on cognitive, emotional, and social growth. Research on AI’s impact on early childhood education and its role in supporting foundational skills would be valuable. Additionally, the research should emphasise the aspect of teacher support, including how AI can assist with lesson planning, assessment, and feedback. It should also explore training programs to help educators use AI effectively. Finally, inclusivity and accessibility are key angles to consider, ensuring AI tools are suitable for all students, including those with disabilities or from diverse backgrounds, and promoting multilingual and multicultural education.

Longitudinal studies are also needed, as current research is fragmented and looking at the short term. Proposals should focus on the need to understand long-term cognitive, social, and emotional impacts, which requires sustained, multi-year investigations. Furthermore, the role of media and digital tools requires attention. Proposals should consider the devices and platforms through which children encounter AI (for example robots, tablets, smartphones etc) and how these shape interactions and learning outcomes.

Relevant research questions to address include:

1.How can AI-powered tools personalise learning experiences safely and effectively and support teachers in addressing diverse student needs?

2.What are the potential benefits and challenges of integrating AI into initial teacher education and continuous professional development programmes?

3.How can AI assist teachers in automating administrative tasks, allowing them to focus more on pedagogy and student engagement?

4.What ethical considerations and potential risks, including in relation to wellbeing, should be taken into account when using AI in education to support teachers and students?

5.What is the typical profile of teachers who are currently using AI-powered tools and which uses and perceived gratifications motivate using AI-powered tool?

6.How can AI tools motivate children to learn?

7.How can AI-based interventions address learning gaps based on individual students’ needs (including disabilities) and learning styles?

8.What changes do educational programmes need to perform on a pedagogical level for the successful integration of AI?

9.What do teachers need to implement the use of AI safely and effectively?

Proposals can apply a variety of methods including rigorous experimental and/or quasi-experimental methods, but also experience sampling and general survey methods, to evaluate the effectiveness of existing AI tools or to test new AI tools. Proposals should evaluate the costs associated with the policy measures or programmes analysed. Proposals should look at different forms of AI tools, e.g. Generative AI, Intelligent Tutoring Systems etc. Proposals should also apply qualitative research methods to cover the ethical dimensions. Interdisciplinary approaches and close cooperation with educational institutions and educators are essential. Cooperation with media literacy organisations is encouraged. Clustering and cooperation among selected projects under this call topic and other relevant projects are strongly encouraged.

Particular attention should be paid to identifying and mitigating biases in AI systems to ensure equity and inclusion in education systems.

HORIZON-CL2-2027-01-TRANSFO-06: Closing the learning gap: uncovering causes and effective policy interventions for declining youth skills in mathematics, reading, and science

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 204 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Provide policymakers with a solid understanding of the structural causes for the decline in young people’s skills levels in mathematics, reading and science, including low and top levels of achievement, observed in the EU over the past 15 years.

2.Generate rigorous, policy-relevant evidence about which teaching practices, programmes and policy actions can be effective to reverse that decline, including the role of curricula, structural aspects of education and training systems, physical and digital learning environments, and innovative teaching and learning methods (including their accessibility).

3.Develop actionable advice to inform policy measures, programmes, future evaluations and actions for education and training systems in the field of basic skills.

Scope: Young people's mathematics, reading and science skills, as measured by large-scale international assessments such as the OECD Programme for International Student Assessment (PISA), have significantly declined in Europe over the past 15 years. This applies both to the low and top levels of achievement. Reversing that trend is one of the fundamental objectives of the Union of Skills.

While the research literature has well analysed the short-term impact of the COVID-19 crisis, the structural causes of the observed decline are still poorly understood. More in-depth research is necessary, using various data sources at national and international level. Several interrelated research questions remain to be addressed, such as:

1.How have changes in teaching methods, curriculum design, and assessment practices influenced the decline in mathematics, reading and science skills over time?

2.What role do digital distractions and shifts in reading habits from paper to digital devices play?

3.What is the role handwriting and drawing for cognitive development?

4.What is the link between acquisition of cognitive skills in maths, science and reading on the one hand and the socio-emotional skills, learning skills, self-regulation, school climate on the other.

5.To what extent does the increasing (also migration-related) heterogeneity of the students make it more difficult to organise learning at school?

6.How does parental involvement affect educational performance?

7.Do different levels of parental involvement affect educational performance?

8.What is the role of cultural institutions such as museums and libraries?

9.What is the combined impact of socio-economic background and gender on gaps in educational performance?

10.How do different levels of investment in public education, and teacher shortages and working conditions affect the educational performance of children?

Proposals should also take into account the perspective of young people and other relevant stakeholders as part of the data collection. Close cooperation with authorities and/or other institutions owning the data is essential and should be ensured.

Understanding the causes of this decline is the pre-condition for analysing the causal impact of various remedial measures and identifying effective policies and programmes to improve young people’s skills in mathematics, reading and science. Proposals should apply experimental and/or quasi-experimental methods for their analysis and could complement them with qualitative research methods. Proposals should also evaluate the costs associated with the policy measures or programmes analysed. Interdisciplinary approaches, combining insights from economics, sociology, psychology, neurosciences and education sciences, and more generally, the social sciences and humanities (SSH), are encouraged. Clustering and cooperation among selected projects under this call topic and other relevant projects are strongly encouraged.

HORIZON-CL2-2027-01-TRANSFO-07: Persons with disabilities: opportunities for labour inclusion and social protection through the life course

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Research and Innovation Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 205 .

Expected Outcome: Projects should contribute to two of the following expected outcomes:

1.Provide implementable, quality, disaggregated and evidence-based data to policymakers and research and innovation stakeholders to bridge the employment gap between persons with disabilities and persons without disabilities.

2.Deliver scalable and replicable inclusive person-centred interventions addressing the situation of persons with disabilities in relation to the labour market in a manner that they are transferable to the new contexts of work, studying and comparing their impacts.

3.Develop innovative policy approaches in the area of social protection for persons with disabilities to compensate the cost associated to disabilities, removing barriers for their participation and encourage them to engage in employment in the open labour market, while at the same time guaranteeing them an adequate level of social protection.

Scope: The UN Convention on the Rights of Persons with Disabilities 206 recognises the right to work for persons with disabilities on an equal basis with others (Art. 27). However, only half of the 42.8 million persons with disabilities of working age in the EU is employed, this being translated into an employment gap in which only 51% of persons with disabilities are employed compared to 75% of persons without disabilities 207 . In addition, persons with disabilities are overrepresented among those inactive in the labour market, not looking for a job due to different barriers, such as a generalised lack of accessibility of workplaces, inaccessible transportation, built environment and infrastructure, insufficient or inadequate reasonable accommodation, lack of flexibility in employment, administrative burdens or incompatibility with disability benefits.

Thus, new and innovative ways of inclusion into the labour market of persons with disabilities need to be explored and tested with the objective to reduce the gaps between persons with and without disabilities, reduce inequalities and promote their social and economic inclusion on an equal basis with others. An assessment of the benefits, including for society and the economy, of employment of persons with disabilities could be carried out.

Research (including through SSH disciplines) should address the disadvantages and barriers faced for increasing inclusion in the labour market of persons with disabilities, collect data on proved effective measures to improve the situation, and provide a thorough analysis of the impact and efficacy of existing policy measures, such as positive discrimination provisions, quotas, employment targets and others. The role of employers, their concerns and good practices for labour inclusion of persons with disabilities needs to be assessed, as well as reasons to circumvent obligations to include employees with disabilities. Moreover, discrimination against persons with disabilities during the hiring process and the impact on job retention could be addressed.

Research should also take stock of existing accessible working environments tools and equipment, as well as reasonable accommodation tools and support at work already provided or still needed and their impact on the employment of persons with disabilities. The role of accessible digital services, digital skills and assistive technologies and other advanced technologies such as Artificial Intelligence (AI) and its potential for advancing the labour inclusion of persons with disabilities may be explored.

Different types of work - adapted to the often-hidden talents of persons with disabilities - should be explored, taking into account their competences and abilities, disability type, level, sex and age. The transition from supported/sheltered employment to the open labour market, including different models such as self-employment and entrepreneurship, re- and upskilling, vocational education and training, could be considered, looking for sustainable pathways to facilitate the process and to be maintained in the long run.

Persons with disabilities are at a higher risk of poverty due to insufficient labour market participation in combination with insufficient social protection and insufficient compensation for extra costs related to disability, including family-based care. The UN Convention on the Rights of Persons with Disabilities recognises the right to social protection and to the enjoyment of that right without discrimination on the basis of disability (Art. 28).

Thus, research is expected to address the issue of social protection through the life course of persons with disabilities, including different aspects such as disability benefits, possible in-kind benefits, coverage of extra costs associated to disabilities, the transition to pension age for persons with disabilities or acquiring disabilities after pension age. Attention should be paid to measures that disincentivise or create barriers to the employment of persons with disabilities in the open labour market. Proposals should consider also the in and out of employment and the possible compatibility with other benefits, such as disability benefits avoiding the benefit trap. The benefit trap needs to be addressed since it may act as a deterrent to take employment for persons with disabilities, who may lose their disability benefits and may be led to in-work poverty.

Data collection is essential to understand the employment participation of persons with disabilities and remains a challenge to collect data disaggregated per type of disability, sex, and age. Thus, applicants are encouraged to ensure harmonised data collection by using Eurostat standards and existing international sets of questions in their areas of research. Applicants are encouraged to involve persons with disabilities and their representative organisations, stakeholders, policymakers and public authorities, social services, citizens and civil society organisations, end-users and service providers.

Projects are also encouraged to explore potential complementarities with projects funded under the Cluster 2 topic HORIZON-CL2-2025-01-TRANSFO-9: “Good practices for increased autonomy of persons with disabilities, including physical, mental, intellectual and sensory disabilities” and Cluster 1 topic HORIZON-HLTH-2025-03-STAYHLTH-01-two-stage: “Improving the quality of life of persons with intellectual disabilities and their families”.

HORIZON-CL2-2027-01-TRANSFO-08: Scaling and deploying innovations in migration management

Call: Culture, Creativity and Inclusive Society - 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 3.75 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 15.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 208 .

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Enhanced impact of EU-funded migration research by identifying and scaling up promising innovations, methodologies, and tools from relevant Horizon 2020 and Horizon Europe projects.

2.A policy innovation ecosystem: Foster collaboration between researchers, policymakers, and practitioners to adapt, scale, and deploy validated models, ensuring their scalability, sustainability, and practical application in diverse EU, national and local contexts.

Scope: Despite significant EU investment in migration research, many innovative solutions to gain insights and foresight remain underutilized in policymaking and practice. This topic aims to bridge that gap by systematically identifying, assessing, and facilitating the adoption of promising approaches developed in past EU-funded migration related projects to ensure a better fungibility between knowledge-oriented activities on past or future trends of migrations and policy making.

Proposals should map and analyse research outputs, methodologies, and innovations from relevant Horizon 2020 and Horizon Europe migration projects, selecting those with high potential for policy uptake, operational implementation, market deployment and scaling. Proposals should consider ways to validate, adapt, and scale up these solutions across different governance levels (EU, national, local) and migration-related domains implementing high ethical standards and ensuring fundamental rights and privacy of all individuals affected. Applicants are encouraged to engage key stakeholders - including policymakers, migration practitioners, researchers (including from SSH disciplines), the private sector; groups or individuals that represent the interests of refugees and migrants and the civil society - to ensure that identified innovations align with real-world needs and implementation pathways and taking into account the political, legal, and cultural specificities of each Member State that influence implementation, while ensuring the solutions are transferable across contexts. Proposals are encouraged to take into consideration the assessment of the societal and political impacts as well as recommendations of previously funded Horizon research projects on migration. To that end, proposals are encouraged to carry out a mapping exercise.

Activities may include pilots, policy labs, co-creation processes, or other mechanisms to enhance the transferability of research outcomes into policies and operational frameworks.

A core element of the action will be fostering a structured dialogue between the research community and decision-makers to ensure continuous knowledge transfer and innovation mainstreaming. The initiative should contribute to a more dynamic, responsive and anticipatory EU migration ecosystem in the intersection of policy and research, in line with the objectives of the EU Pact on Asylum and Migration and other relevant policy frameworks.

Proposals may incorporate a gender-sensitive and intersectional approach in their research if relevant, by collecting data based for example on age, ability, ethnic and racial background, sex, socioeconomic status, and religion or belief to ensure that identified migration-related innovations align with real-world needs of people in migratory situation.

Proposals should delineate the plans for further applications of the knowledge, solutions and findings generated by their research at national and EU level. Knowledge and findings may be used with EU co-financing of instruments such as the Asylum, Migration and Integration Fund (AMIF) and/or subsequent funding instruments.

Proposals may envisage JRC participation, particularly to support the assessment of relevance, scalability and uptake of innovative solutions in migration management. The JRC could contribute with its knowledge of EU's migration systems, foresight, and capacity to bridge research and policymaking.

HORIZON-CL2-2027-02-TRANSFO-09-two-stage: Improving socio-economic outcomes for persons with dementia and informal caregivers

Call: Culture, Creativity and Inclusive Society - 2027 - Two-stage

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.20 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 16.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 209 .

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects should contribute to all of the following expected outcomes:

1.Persons with dementia experience improved social, mental and socio-economic outcomes through the development and implementation of person-centred interventions that enhance autonomy, inclusion, and quality of life.

2.Informal caregivers benefit from reduced emotional, financial, and physical burden thanks to evidence-based support measures, policies, and services that improve their well-being and economic resilience.

3.Support networks, long-term care and healthcare systems provide more integrated and accessible care for people with dementia and their caregivers through strengthened coordination between healthcare providers, long-term care and social services, and community organisations.

4.Researchers (including from SSH disciplines) and policymakers have access to improved, gender-sensitive data on dementia care to inform policies (in particular national strategies and EU aging policy), optimise resource allocation, and enhance the effectiveness of care models.

Scope: Dementia is a progressive neurological disease. The number of people with dementia will double by 2050 in the European Union, from 10 million currently. As people with dementia lose their ability to care for themselves, care is often provided by informal caregivers, which mostly include family members, and more specifically women. In fact, 71% of the estimated time devoted to unpaid care for people with dementia is devoted by women. Women, especially those in vulnerable situations such as those from lower socio-economic backgrounds, often face additional pressures in managing caregiving responsibilities, which may exacerbate pre-existing inequalities. Furthermore, the provision of informal care has a negative impact on the economic and social life of the caregiver, as the time spent on the person with dementia is time not spent in employment or with other friends and family. Additionally, informal care is unpaid and has been estimated to have negative financial consequences for the caregivers themselves and the society as a whole. Studies have also shown that people with dementia and their informal caregivers have higher rates of depression than the general population.

While there is a lot of attention for clinical research, there is far less attention for the aspects surrounding the economic and social life, financial stability and the mental health of persons with dementia and informal caregivers. Many innovative solutions have been proposed, but few have been implemented on a wide scale. Social public policies with different design and funding that take into account the substitution and complementarities between formal and informal caregivers have been implemented to reduce the burden of the informal caregivers. What is needed, are systemic interventions focussed on improving these aspects for patients and informal caregivers and addressing the gendered nature of caregiving.

Priority should be given to scaling up and contextualising interventions that have already shown promise or effectiveness at smaller scale, rather than developing entirely new or untested solutions. Applicants should provide a robust methodological framework for evaluating the effectiveness of the interventions. Proposals should also assess the economic feasibility and sustainability of the interventions, including cost-effectiveness and potential integration into existing health and social care systems or policy frameworks. Proposals can focus on groups in vulnerable situations (e.g. migrants, lower socio-economic populations, people with disabilities) for gender-responsive and inclusive interventions. Social inequality analyses are therefore also recommended. Community based models (e.g. dementia-friendly cities, peer-support groups) can be included, as well as analyses of the quality of residence of people with dementia. Proposals are encouraged to include technology and digital tools in the scope of their work.

Considering the already high burden of dementia, interventions should be implemented in at least four Member States or Associated Countries. Considering the focus, it is of the upmost importance that informal caregivers are involved in the research throughout (in the design and implementation) to ensure that interventions are tailored to the real needs of caregivers and the individuals they care for.

Proposals should outline clear, evidence-based strategies for tailoring, deploying, and assessing these interventions at individual, family, community, and societal levels, while addressing the specific needs of different caregiver demographics.

OTHER ACTIONS not subject to calls for proposals

Grants to identified beneficiaries

1. Presidency event (Lithuania): Re-thinking EU's competitiveness: How do cultural and creative industries contribute?

Expected Outcome:

The project is expected to contribute to all the following expected outcomes:

1.Policymakers, industry leaders, academics and practitioners are aware of effective policy approaches to boost the Cultural and Creative Industries (CCIs) as drivers of prosperity and competitiveness and are motivated to put them in practice.

2.Cross-sectorial dialogue has contributed to deeper shared insights on the key challenges, opportunities and best practice in boosting the CCIs.

3.The understanding and consensus on the role and measuring of the socio-economic impact of CCIs in fostering the competitiveness of Europe as well as of digitalisation challenges and opportunities is enhanced.

4.The collaboration between public and private stakeholders to foster innovation and technological adoption in CCIs is strengthened.

5.A widely supported declaration summarizes the important conclusions and contributes to a common momentum across the EU.

Expected Impact:

The proposal should set out a credible pathway to contributing to the following impact of the Horizon Europe Strategic Plan:

1.The full potential of cultural heritage, arts and cultural and creative industries and sectors as drivers of both sustainable innovation and a European sense of belonging is realised through a continuous engagement with society, citizens and economic sectors.

Scope:

The conference should gather experts from the EU Member States including representatives from cultural institutions, creative entrepreneurs, researchers, technology developers and policymakers. It should cover policy frameworks, innovation case studies, technological trends, and cross-sectoral impacts. The event should aim to catalyse actionable insights and foster a shared vision for the future of CCIs in Europe.

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 20 of the Horizon Europe Framework Programme and Rules for Participation.

Procedure: The evaluation committee will be composed fully by representatives of EU institutions.

Legal entities:

The Ministry of Culture of the Republic of Lithuania, legal entity (budgetary institution) code188683671, J. Basanavičiaus str. 5, LT-01118, Vilnius, E-mail: info@lrkm.lt.

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: First semester 2027

Indicative budget: EUR 0.30 million from the 2027 budget

2. Presidency event (Greece): Cultural Heritage for Sustainable Futures

Expected Outcome:

The project is expected to contribute to all the following expected outcomes:

Culture and Tourism

1.Promotion of responsible and sustainable tourism that contributes to the preservation of cultural heritage and local identity

2.Strategies for managing overtourism and mitigating its social, environmental, and cultural impacts

3.Models for responsible planning and site management, including through the employment of AI and other advanced technologies, ensuring cultural heritage is safeguarded in harmony with natural landscapes and local ecosystems

4.Participatory approaches that involve local communities and multiple stakeholders in the sustainable management of heritage and tourism

5.Development of sustainable tourism practices aligned with the principles of circular economy, fostering cross-cultural appreciation of cultural sites while preserving historical integrity and cultural authenticity

Culture and Climate

1.Present effective measures to mitigate extreme climate impacts on cultural heritage, including preventive strategies, adaptive reuse, and resilience planning.

2.Propose innovative solutions for measuring and reducing the carbon footprint of the cultural and creative sectors.

3.Introduce tools and methodologies to monitor the contribution of cultural heritage to sustainable economic growth, climate neutrality, and social well-being.

4.Strengthen the adaptive capacity of the cultural heritage sector in response to climate change and other disasters.

5.Highlight how tangible and intangible cultural heritage represent a resource for climate change adaptation and mitigation.

Expected Impact:

The proposal should set out a credible pathway to contributing to the following impact of the Horizon Europe Strategic Plan:

1.The full potential of cultural heritage, arts and cultural and creative industries and sectors as drivers of both sustainable innovation and a European sense of belonging is realised through a continuous engagement with society, citizens and economic sectors.

Scope:

The event should tackle the dual challenge of safeguarding cultural heritage while advancing sustainable development and climate adaptability. It should explore the contribution of cultural heritage to the European Green Deal, the digital and social transitions, and sustainable tourism, with a particular emphasis on responsible planning, community-driven approaches, and the circular economy. The event should convene policymakers, researchers, cultural practitioners, tourism professionals, and local communities to share best practices, co-create innovative solutions, and foster inclusive, participatory management models that balance cultural, environmental, and economic objectives. Special focus should be given to addressing the impacts of climate change and overtourism on cultural sites - while ensuring that cultural heritage remains a dynamic, inclusive, and accessible resource for future generations.

This grant will be awarded without a call for proposals according to Article 198(e) of the Financial Regulation and Article 20 of the Horizon Europe Framework Programme and Rules for Participation.

Procedure: The evaluation committee will be composed fully by representatives of EU institutions.

Legal entities:

GENIKI GRAMMATIA EREVNAS KAI KAINOTOMIAS (GSRI), GENERAL SECRETARIAT FOR RESEARCH AND INNOVATION, Mesogeion Avenue 14-18, Athens 115 10, Greece

Form of Funding: Grants not subject to calls for proposals

Type of Action: Grant to identified beneficiary according to Financial Regulation Article 198(e) - Coordination and support action

The general conditions, including admissibility conditions, eligibility conditions, award criteria, evaluation and award procedure, legal and financial set-up for grants, financial and operational capacity and exclusion, and procedure are provided in parts A to G of the General Annexes

Indicative timetable: Second semester 2027

Indicative budget: EUR 0.30 million from the 2027 budget

Public procurements

1. Studies, conferences, events and outreach activities

A number of specific contracts will be signed under existing framework contracts in order to: (i) support the dissemination and exploitation of project results; (ii) contribute to the definition of future challenge priorities; (iii) undertake citizen surveys such as Eurobarometers, (iv) carry out specific evaluations of programme parts; and (v) organise conferences, events and outreach activities. Should existing framework contracts prove unsuitable or insufficient to support the abovementioned activities, one or more calls for tender may be launched as appropriate.

Subject matter of the contracts envisaged: studies, technical assistance, conferences, events and outreach activities within the scope of Cluster 2 ‘Culture, Creativity and Inclusive Society’.

Form of Funding: Procurement

Type of Action: Public procurement

Indicative timetable: 2026

Indicative budget: EUR 1.00 million from the 2026 budget

2. Studies, conferences, events and outreach activities

A number of specific contracts will be signed under existing framework contracts in order to: (i) support the dissemination and exploitation of project results; (ii) contribute to the definition of future challenge priorities; (iii) undertake citizen surveys such as Eurobarometers, (iv) carry out specific evaluations of programme parts; and (v) organise conferences, events and outreach activities. Should existing framework contracts prove unsuitable or insufficient to support the abovementioned activities, one or more calls for tender may be launched as appropriate.

Subject matter of the contracts envisaged: studies, technical assistance, conferences, events and outreach activities within the scope of Cluster 2 ‘Culture, Creativity and Inclusive Society’.

Form of Funding: Procurement

Type of Action: Public procurement

Indicative timetable: 2027

Indicative budget: EUR 1.00 million from the 2027 budget

Other budget implementation instruments

1. Expertise for the design, implementation and evaluation of Cluster 2, Culture, Creativity and Inclusive Society

This action will support the provision of independent expertise for advising and assisting the Commission services with the design, implementation and evaluation of EU research and innovation policies in the thematic areas covered by Cluster 2. Individual experts will work in the following policy and thematic areas:

1.Democracy and governance

2.Cultural heritage, cultural and creative sectors and industries

3.Social and economic transformations

4.Migration, refugee and asylum policies

5.Social sciences and humanities, including their integration in Horizon Europe programme parts

6.Inter-, multi- and transdisciplinarity; impact assessment

The tasks of individual experts would include:

Portfolio analysis of projects funded under Horizon Europe or previous European research and innovation programmes; analysis of the state-of-the-art at European and international level; participation in international symposia organised by Commission services, including the drafting of reports; assistance for setting-up a research and innovation strategy for selected domains; policy recommendations and options assisting Commission services in elaborating evidence-based and scientifically sound policy proposals.

The advice provided by each individual expert will focus on specific areas and policy relevant projects' results and how results and outcome could be used for policymaking and policy follow-up initiatives. These activities will not duplicate past or ongoing Commission work and will be essential to enable Commission services to support the policymaking process in the above-mentioned policy areas.

The individual experts' tasks will include attending bilateral meetings with Commission services, presentations at workshops and symposia, remote drafting and preparatory work. The experts will be highly qualified and specialised and will be selected on the basis of their knowledge and experience.

A special allowance of EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest.

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative timetable: 2026

Indicative budget: EUR 0.20 million from the 2026 budget

2. External expertise - Monitors


This action will support the use of appointed independent experts for the monitoring of running actions (grant agreement, grant decision, public procurement actions, financial instruments) funded under Horizon Europe and previous Framework Programmes for Research and Innovation and where appropriate include ethics checks, as well as compliance checks regarding the Gender Equality Plan eligibility criterion.

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative timetable: 2026

Indicative budget: EUR 0.60 million from the 2026 budget

3. Expertise for the design, implementation and evaluation of Cluster 2, Culture, Creativity and Inclusive Society

This action will support the use of independent expertise for advising and assisting the Commission services with the design, implementation and evaluation of EU research and innovation policies in the thematic areas covered by Cluster 2. Individual experts will work in the following policy and thematic areas:

1.Democracy and governance

2.Cultural heritage, cultural and creative sectors and industries

3.Social and economic transformations

4.Migration, refugee and asylum policies

5.Social sciences and humanities, including their integration in Horizon Europe programme parts

6.Inter-, multi- and transdisciplinarity; impact assessment

The tasks of individual experts would include:

Portfolio analysis of projects funded under Horizon Europe or previous European research and innovation programmes; analysis of the state-of-the-art at European and international level; participation in international symposia organised by Commission services, including the drafting of reports; assistance for setting-up a research and innovation strategy for selected domains; policy recommendations and options assisting Commission services in elaborating evidence-based and scientifically sound policy proposals.

The advice provided by each individual expert will focus on specific areas and policy relevant projects' results and how results and outcome could be used for policymaking and policy follow-up initiatives. These activities will not duplicate past or ongoing Commission work and will be essential to enable Commission services to support the policymaking process in the above-mentioned policy areas.

The individual experts' tasks will include attending bilateral meetings with Commission services, presentations at workshops and symposia, remote drafting and preparatory work. The experts will be highly qualified and specialised, and will be selected on the basis of their knowledge and experience.

A special allowance of EUR 450/day will be paid to the experts appointed in their personal capacity who act independently and in the public interest.

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative timetable: 2027

Indicative budget: EUR 0.20 million from the 2027 budget

4. External expertise - Monitors

This action will support the use of appointed independent experts for the monitoring of running actions (grant agreement, grant decision, public procurement actions, financial instruments) funded under Horizon Europe and previous Framework Programmes for Research and Innovation and where appropriate include ethics checks, as well as compliance checks regarding the Gender Equality Plan eligibility criterion.

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative budget: EUR 0.60 million from the 2027 budget

Budget 210   211

Budget line(s)

2026 Budget (EUR million)

2027 Budget (EUR million)

Calls

HORIZON-CL2-2026-01

298.50

from 01.020220

298.50

HORIZON-CL2-2026-02

60.00

from 01.020220

60.00

HORIZON-CL2-2027-01

277.00

from 01.020220

277.00

HORIZON-CL2-2027-02-TWO-STAGE

58.00

from 01.020220

58.00

Other actions

Grant awarded without a call for proposals according to Financial Regulation Article 198(e)

0.60

from 01.020220

0.60

Public procurement

1.00

1.00

from 01.020220

1.00

1.00

Expert contract action

0.80

0.80

from 01.020220

0.80

0.80

Estimated total budget

360.30

337.40

(1)    see topic HORIZON-CL2-2026-02-TRANSFO-01 in this Work Programme
(2)     list-3rd-country-participation_crea_en.pdf (europa.eu)
(3)     https://ec.europa.eu/info/strategy/priorities-2019-2024/stronger-europe-world/global-gateway_en
(4)    For a full list of ESFRI-listed research infrastructures see https://ri-portfolio.esfri.eu/ri-portfolio/table . In the social sciences and humanities domain, see for example: CESSDA - Consortium of European Social Science Data Archives ( https://www.cessda.eu/ ), ESS – European Social Survey ( https://www.europeansocialsurvey.org/ ), SHARE - Survey of Health, Ageing and Retirement in Europe ( https://www.share-eric.eu/ ) or the European Research Infrastructure for Heritage Science ( https://www.e-rihs.eu ).
(5) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(6)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(7) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(8)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(9) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(10)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(11) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(12)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(13)    The 2025 report of the V-Dem Institute (“25 years of Autocratization-Democracy Trumped?”) confirms the appalling signs, indicators and tendencies captured over previous years of measurement: “The trend of the ‘third wave of autocratization’ is deepening and spreading. That includes weakening of democracy in some established liberal democracies, breakdown of democracy in countries that were democratic for most of the 21st century, as well as deepening of autocracy in already autocratic states […] The global democratic decline deepens, regardless of how we slice the data and whichever measure we use” (pp. 9 and 10)
(14)    For a full list see https://ri-portfolio.esfri.eu/ri-portfolio/table . In the social sciences domain, see for example: CESSDA - Consortium of European Social Science Data Archives ( https://www.cessda.eu/ ), ESS – European Social Survey ( https://www.europeansocialsurvey.org/ ), SHARE - Survey of Health, Ageing and Retirement in Europe ( https://www.share-eric.eu/ ) or the European Holocaust Research Infrastructure ( https://ehri-project.eu/ )
(15)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(16)    Entails, but not limited to, public representatives, journalists, investigative reporters, human rights defenders, activists, civil society actors, political figures, and anonymous individuals engaging in the public sphere.
(17)    In this topic, political activities and being “politically active” should be understood as going beyond formal institutional structures to include a wide range of public engagement activities, such as activism, community organising, and civic participation. Moreover, the topic calls for research that goes beyond those already active in public life, by examining how violence and harassment affect the aspirations, motivations, and trajectories of girls, women, and LGBTIQ people who seek to engage in public and political spheres.
(18)    Political Guidelines for the next European Commission 2024-2029, https://europa.eu/!wywg4P , page 20.
(19)    COM(2025)97 - Communication from the Commission to the European Parliament, the Council, the European Economic and Social Committee and the Committee of the Regions. A Roadmap for Women’s Rights. Principle 7 of the Roadmap’s annex reaffirms every woman’s right to active and safe participation in public life and outlines key objectives to protect and promote this right.
(20)    Racist and anti-LGBTIQ rhetoric especially is on the rise: https://fra.europa.eu/en/publication/2024/lgbtiq-crossroads-progress-and-challenges ; https://fra.europa.eu/en/news/2023/black-people-eu-face-ever-more-racism ; https://www.ilga-europe.org/report/annual-review-2023/
(21)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(22)    In the context of this call “low-income and low-middle income countries” are understood as the low to middle income non-associated third countries in the list of participating countries according to the Horizon Europe rules for participation and proposal procedure. Source: European Commission, “List of Participating Countries in Horizon Europe,” Version 5.3 (24.01.2024), p. 3. Available at: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/common/guidance/list-3rd-country-participation_horizon-euratom_en.pdf
(23)    Fragile contexts refer to low- and middle-income countries or situations characterized by weak or failing institutions, limited governance, conflict or violence, economic instability, and humanitarian crises, which hinder the achievement of development goals and undermine the well-being of citizens. These contexts are often marked by a lack of transparency, accountability, and participation in decision-making processes, and may be identified through various indicators.
(24)    Such as the EU Action Plan on Human Rights and Democracy 2020 – 2027, which is linked to the Global Gateway initiative and EU cooperation instruments linked to the Global Gateway initiative and EU cooperation instruments: https://www.eeas.europa.eu/sites/default/files/documents/2024/Action-Plan-EN_2020-2027.pdf , https://www.eeas.europa.eu/sites/default/files/documents/2024/Action-Plan-EN_2020-2027.pdf . Examples of EU initiatives include Team Europe Democracy, the Territorial Approach to local Development, and the Neighbourhood, Development and International Cooperation Instrument, which aim to promote human rights and democracy worldwide by supporting good governance, the rule of law, and human rights protection.
(25)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(26)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52023DC0667
(27)    News media organisations are those in which a core activity is the regular production and dissemination of professional news content and/or factual programming, irrespective of its format (audio-visual media, broadcasting, printed news, newswires, multimedia, radio, online, etc.), under the editorial workflows, standards and responsibility of the said organisation.
(28)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(29)     The European Media Industry Outlook | Shaping Europe’s digital future
(30)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(31)    In 2020 and 2021, the Commission adopted five strategies to create the conditions for everyone to live, thrive and lead regardless of differences based on gender, racial or ethnic origin, religion or belief, disability, age or sexual orientation: the LGBTIQ equality strategy 2020-2025, the gender equality strategy 2020-2025, the strategy for the rights of persons with disabilities 2021-2030, the EU anti-racism action plan 2020-2025, the EU Roma strategic framework for equality, inclusion, and participation 2020-2030. Under the 2024-2029 political cycle, the Commission has committed to renew the strategies on Gender Equality, LGBTIQ and anti-racism.
(32)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(33)    Such as the Intergovernmental Panel on Climate Change (IPCC), the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES), the Intergovernmental Science-Policy Panel on Chemicals, Waste and Pollution (ISP-CWP), the International Resource Panel (IRP), and the International Platform for Ocean Sustainability (IPOS)
(34)    Such as the G7, G20, G77, BRICS, Small Island Developing States, etc.
(35)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(36)     https://www.unwomen.org/en/news/stories/2019/10/compilation-the-power-of-women-peacebuilders
(37)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(38)     https://ec.europa.eu/commission/presscorner/detail/en/ip_24_1707
(39)     https://digital-strategy.ec.europa.eu/en/library/code-conduct-disinformation
(40)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(41)    The Action plan on basic skills (March 2025) explicitly recognises citizenship as a basic skill, and it defines it as: “The ability to act responsibly and participate fully in civic life, grounded in an understanding of social, economic, legal and political structures. This involves understanding and evaluation of civic and democratic concepts, institutions and processes, including democracy, media literacy, crisis preparedness and respect for others and freedom of speech.”
(42)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(43)     https://commission.europa.eu/topics/defence/safer-together-path-towards-fully-prepared-union_en
(44)     https://ec.europa.eu/commission/presscorner/detail/en/ip_20_2250
(45)     https://commission.europa.eu/strategy-and-policy/priorities-2019-2024/europe-fit-digital-age/digital-services-act_en
(46)     https://digital-strategy.ec.europa.eu/en/policies/european-digital-media-observatory
(47)    Joint Communication to the European Parliament, the European Council, the Council, the European Economic and Social Committee and the Committee of the Regions on the European Preparedness Union Strategy
(48)    For instance, “Guidelines for teachers and educators on tackling disinformation and promoting digital literacy through education and training”, Publications Office of the European Union, 2022, https://data.europa.eu/doi/10.2766/28248 ; or the UNESCO’s “Global Standards for Media and Information Literacy Curricula Development Guidelines”
(49)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(50)     https://commission.europa.eu/strategy-and-policy/policies/justice-and-fundamental-rights/combatting-discrimination/racism-and-xenophobia/combating-hate-speech-and-hate-crime_en
(51)    See, for example: https://edmo.eu/
(52)     https://home-affairs.ec.europa.eu/networks/eu-knowledge-hub-prevention-radicalisation_en
(53)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(54)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(55)    The Action plan on basic skills (March 2025) explicitly recognises citizenship as a basic skill, and it defines it as: “The ability to act responsibly and participate fully in civic life, grounded in an understanding of social, economic, legal and political structures. This involves understanding and evaluation of civic and democratic concepts, institutions and processes, including democracy, media literacy, crisis preparedness and respect for others and freedom of speech.”
(56)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(57)    Regulation (EU) 2024/1689 of the European Parliament and of the Council of 13 June 2024 laying down harmonised rules on artificial intelligence and amending Regulations (EC) No 300/2008, (EU) No 167/2013, (EU) No 168/2013, (EU) 2018/858, (EU) 2018/1139 and (EU) 2019/2144 and Directives 2014/90/EU, (EU) 2016/797 and (EU) 2020/1828 (Artificial Intelligence Act).
(58)    Including how trustworthy and human-centric AI can be leveraged to support content moderation, fact-checking, and online monitoring.
(59)     https://joint-research-centre.ec.europa.eu/projects-and-activities/innovations-public-governance_en
(60)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(61)    In the context of this call, the “EU Neighbourhood” is understood as the group of countries covered by the European Neighbourhood Policy (ENP), which includes countries to the East (Armenia, Azerbaijan, Belarus, Georgia, Moldova, and Ukraine) and to the South (Algeria, Egypt, Israel, Jordan, Lebanon, Libya, Morocco, Palestine, Syria, and Tunisia). For more information: https://enlargement.ec.europa.eu/european-neighbourhood-policy_en and https://north-africa-middle-east-gulf.ec.europa.eu/what-we-do/southern-neighbourhood_en
(62)    In the context of this call “low-income and low-middle income countries” are understood as the low to middle income non-associated third countries in the list of participating countries according to the Horizon Europe rules for participation and proposal procedure. Source: European Commission, “List of Participating Countries in Horizon Europe,” Version 5.3 (24.01.2024), p. 3. Available at: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/common/guidance/list-3rd-country-participation_horizon-euratom_en.pdf
(63)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(64)     The European Media Industry Outlook | Shaping Europe’s digital future
(65)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(66)    In this context, when referring to private companies, we specifically mean large undertakings, namely multinational and global corporations, including industry and tech platforms, as opposed to small and medium-sized enterprises (SMEs).
(67)    For instance, but not limited to: HORIZON-CL2-2023-DEMOCRACY-01-03: New approaches for combatting corruption and other undue influences on political decision-making.
(68)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(69)    In the context of this call, the “EU Neighbourhood” is understood as the group of countries covered by the European Neighbourhood Policy (ENP), which includes countries to the East (Armenia, Azerbaijan, Belarus, Georgia, Moldova, and Ukraine) and to the South (Algeria, Egypt, Israel, Jordan, Lebanon, Libya, Morocco, Palestine, Syria, and Tunisia). For more information: https://enlargement.ec.europa.eu/european-neighbourhood-policy_en and https://north-africa-middle-east-gulf.ec.europa.eu/what-we-do/southern-neighbourhood_en
(70)    In the context of this call, the “EU Neighbourhood” is understood as the group of countries covered by the European Neighbourhood Policy (ENP), which includes countries to the East (Armenia, Azerbaijan, Belarus, Georgia, Moldova, and Ukraine) and to the South (Algeria, Egypt, Israel, Jordan, Lebanon, Libya, Morocco, Palestine, Syria, and Tunisia). For more information: https://enlargement.ec.europa.eu/european-neighbourhood-policy_en and https://north-africa-middle-east-gulf.ec.europa.eu/what-we-do/southern-neighbourhood_en
(71)    In the context of this call “low-income and low-middle income countries” are understood as the low to middle income non-associated third countries in the list of participating countries according to the Horizon Europe rules for participation and proposal procedure. Source: European Commission, “List of Participating Countries in Horizon Europe,” Version 5.3 (24.01.2024), p. 3. Available at: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/common/guidance/list-3rd-country-participation_horizon-euratom_en.pdf
(72)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(73)     https://commission.europa.eu/document/download/e6cd4328-673c-4e7a-8683-f63ffb2cf648_en?filename=Political%20Guidelines%202024-2029_EN.pdf
(74)     https://ec.europa.eu/commission/presscorner/detail/en/ip_20_2250
(75)     https://ec.europa.eu/commission/presscorner/detail/en/ip_23_6453
(76)    For the roadmap for women’s rights, see the announcement of its adoption with links to the communication and its annex: https://ec.europa.eu/commission/presscorner/detail/en/ip_25_681
(77)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A52021DC0101
(78)     https://www.ohchr.org/en/instruments-mechanisms/instruments/convention-rights-persons-disabilities
(79)    Council conclusions of 21 May 2014 on cultural heritage as a strategic resource for a sustainable Europe (2014/C 183/08) https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52014XG0614(08)
(80)     CETS 199 - Council of Europe Framework Convention on the Value of Cultural Heritage for Society (coe.int)
(81)    See further for instance https://research-and-innovation.ec.europa.eu/research-area/social-sciences-and-humanities/cultural-heritage-and-cultural-and-creative-industries-ccis/cultural-heritage-cloud_en
(82)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(83)    For information on these initiatives, see https://science-art-society.ec.europa.eu/front and https://starts.eu/
(84)    In the context of this topic, artistic intelligence can be understood as the collaborative capacity of artistic research and practice to generate and drive innovation, impact, and value by integrating creativity with scientific, technological, and cultural knowledge, particularly through cross-disciplinary collaboration, as demonstrated in initiatives such as STARTS and SciArt. Proposals can critically explore and develop the definition.
(85)    M. Draghi (2024), The future of European competitiveness. Part B: In-depth analysis and recommendations, p. 258, 272.
(86)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(87)    In the context of this topic, a ‘creative startup’ should be understood as a private company that falls under the definition of cultural and creative industries as defined in the European Parliament Resolution ‘A coherent EU policy for cultural and creative industries’ ( https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52016IP0486&from=EN ), is younger than ten years and has an innovative product and/or service and/or business model that it aims to scale up.
(88)    In the context of this topic, ‘disruptive innovation’ should be understood in the sense used by the European Innovation Council, but with no requirement to be based on deep tech; as an innovation which radically changes the way of operation (‘of doing things’), and therefore creates new market(s) or has a significant impact on current markets, on economic activity of firms and/or on the public sector or society at large.
(89)    The definition of scaleups by the Organisation for Economic Co-operation and Development (OECD) requires that a company grows at an annual rate of 20% or more over three consecutive years in terms of number of employees or turnover. In the context of this call topic, such growth rate in one year / 2 consecutive years is sufficient.
(90)    SWD(2024) 77 final https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52024SC0077
(91)    E.g. the EIT Culture & Creativity KIC , Cultural and Creative Regional Ecosystems , Digital Innovation Hubs in the cultural and creative sectors , Creative Innovation Labs
(92)    See further COM(2025) 270 https://research-and-innovation.ec.europa.eu/document/download/2f76a0df-b09b-47c2-949c-800c30e4c530_en
(93)     https://eit-culture-creativity.eu/
(94)    Such as for instance https://eic.ec.europa.eu/eic-fund/trusted-investors-network_en
(95)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(96)    “CCSI relate to all sectors and industries whose activities are based on cultural values, cultural diversity and individual and/or collective artistic and other creative expressions, whether those activities are market or non-market oriented, whatever the type of structure that carries them out, and irrespective of how that structure is financed. Those activities include the development of skills and talent with the potential to generate innovation, the creation of wealth and jobs through the production of social and economic value, including from intellectual property management. Those activities relate also to the development, the production, the creation, the dissemination and the preservation of goods and services which embody cultural, artistic or other creative expressions, as well as related functions such as education and management. The cultural and creative sectors include, inter alia, architecture, archives, the arts, libraries and museums, artistic crafts, audiovisual (including film, television, software, video games, multimedia and recorded music), tangible and intangible cultural heritage, design, creativity-driven high-end industries and fashion, festivals, music, literature, performing arts (including theatre and dance), books and publishing (newspapers and magazines), radio and visual arts, and advertising” Decision (EU) 2021/820 of 20 May 2021 on the Strategic Innovation Agenda of the European Institute of Innovation and Technology (EIT) 2021-2027: Boosting the Innovation Talent and Capacity of Europe and repealing Decision No 1312/2013/EU, Appendix I, footnote nr. 26.
(97)    Communication from the Commission to the European Parliament, the Council, the European Economic and Social Committee and the Committee of the Regions” AI Continent Action Plan” COM (2025) 165 final https://digital-strategy.ec.europa.eu/en/library/ai-continent-action-plan . Under the umbrella of the AI Continent Action Plan, the Apply AI strategy aims at boosting the use of AI in EU strategic industries, including the cultural and creative sectors. The AI Continent Action Plan also announces the preparation of a dedicated AI strategy for the cultural and creative sectors focused on ensuring that AI enables and reinforces human creativity and that it contributes to safeguarding European cultural and linguistic diversity.
(98)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(99)    See, among others, JRC’s Generative AI Outlook Report - Exploring the Intersection of Technology, Society and Policy ,2025.
(100)    Communication from the Commission to the European Parliament, the Council, the European Economic and Social Committee and the Committee of the Regions” AI Continent Action Plan” COM (2025) 165 final https://digital-strategy.ec.europa.eu/en/library/ai-continent-action-plan . Under the umbrella of the AI Continent Action Plan, the Apply AI strategy aims at boosting the use of AI in EU strategic industries, including the Cultural and Creative Sectors. The aAI Continent Action Plan also announces the preparation of a dedicated AI strategy for the cultural and creative sectors focused on ensuring that AI enables and reinforces human creativity and that it contributes to safeguarding European cultural and linguistic diversity.
(101)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(102)    Among others: Cultural Relations Platform, connecting cultural practitioners worldwide; S+T+Arts4Africa digital innovation in African sub-Saharan culture and digital innovation hubs; Africa-Europe Partnerships for Culture, focusing on artistic co-creation and cooperation; European Spaces of Culture: innovative collaboration models in cultural relations between EU and extra-EU local partner organisations; Creative Africa: Audiovisual for cross-border cooperation in the audio-visual sector across the entire value chain; Strengthening African-European Museum Partnerships: an African-European museums platform to develop a new multilateral framework based on co-creation; CreatiFI: Financial instrument to support creative industries; ACP-EU Culture: assist the socio-economic development of the ACP countries by supporting their cultural and creative sectors; ProCultura: contribute to the increase of employment and income-generating activities in the cultural and creative sector of the Portuguese-speaking African countries and East Timor; EU-UNESCO Facility: technical assistance to support cultural policy strengthening and the implementation of the UNESCO 2030 Culture Indicators, the framework to measure and assess culture’s contribution to sustainable development; Transcultura: deepen integration within the Caribbean region and strengthening people-to-people cooperation with the European Union.
(103)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(104)    Building i.a. on the European Language Equality (ELE) project reports analysing the linguistic landscape of Europe, providing insights into the availability and quality of digital tools and resources for various European languages.
(105)     ALT-EDIC - European Commission
(106)    Security practitioners has the meaning of organisations or agencies actively engaged in security operations, involved in e.g., law enforcement, customs, environmental crime management, smuggling and trafficking fighting and counter-terrorism, border and maritime surveillance, public safety, fundamental rights, etc.
(107)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(108)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52020DC0605
(109)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52021DC0170
(110)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52022DC0800
(111)     Council Conclusions on the fight against trafficking in cultural goods ‒ Council conclusions (8 June 2023) (10249/23)
(112)     Concept on Cultural heritage in conflicts and crises. A component for peace and security in European Union’s external action. (9962/21)
(113)     Council Conclusions on EU Approach to Cultural Heritage in conflicts and crises (9837/21)
(114)     https://www.europol.europa.eu/publications-events/main-reports/socta-report
(115)     EUROPEAN UNION SERIOUS AND ORGANISED CRIME THREAT ASSESSMENT 2025. THE CHANGING DNA OF SERIOUS AND ORGANISED CRIME.
(116)     https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/projects-details/31077817/101003506
(117)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52020DC0605
(118)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52021DC0170
(119)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52022DC0800
(120)     https://research-and-innovation.ec.europa.eu/research-area/social-sciences-and-humanities/cultural-heritage-and-cultural-and-creative-industries-ccis/cultural-heritage-cloud_en
(121)     https://culture.ec.europa.eu/news/the-eu-presents-expert-recommendations-on-safeguarding-cultural-heritage-in-ukraine
(122)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(123)    CCIs as defined in the European Parliament Resolution ‘A coherent EU policy for cultural and creative industries’: https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52016IP0486&from=EN
(124)    See for instance Open Method of Coordination report ‘ The role of public policies in developing entrepreneurial and innovation potential of the cultural and creative sectors
(125)    Including projects funded under the call topics HORIZON-CL2-2021-HERITAGE-01-03, HORIZON-CL2-2022-HERITAGE-01-04, HORIZON-CL2-2022-HERITAGE-01-05, HORIZON-CL2-2022-HERITAGE-01-06, HORIZON-CL2-2022-HERITAGE-01-09, HORIZON-CL2-2022-HERITAGE-02-01, HORIZON-CL2-2023-HERITAGE-01-02, HORIZON-CL2-2023-HERITAGE-01-06, HORIZON-CL2-2024-HERITAGE-01-02, HORIZON-CL2-2024-HERITAGE-01-03, HORIZON-CL2-2025-01-HERITAGE-04, HORIZON-CL2-2025-01-HERITAGE-05, HORIZON-CL2-2025-01-HERITAGE-06.
(126)     https://www.eit.europa.eu/eit-community/eit-culture-creativity
(127)     https://pact-for-skills.ec.europa.eu/about/industrial-ecosystems-and-partnerships/creative-and-cultural-industries_en
(128)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(129)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(130)    “The frugal innovation process is a problem-oriented, creative approach to problem solving which starts from user needs and works from the bottom up to develop contextually appropriate solutions. It tends to be frugal both in ends and means,” Study on frugal innovation and reengineering of traditional techniques,2017 https://op.europa.eu/en/publication-detail/-/publication/20d6095a-2a44-11e7-ab65-01aa75ed71a1 , see also https://op.europa.eu/en/publication-detail/-/publication/639c142b-f260-11ef-981b-01aa75ed71a1/language-en
(131) https://www.europarl.europa.eu/topics/en/article/20151201STO05603/circular-economy-definition-importance-and-benefits    “The circular economy is a model of production and consumption, which involves sharing, leasing, reusing, repairing, refurbishing and recycling existing materials and products as long as possible. In this way, the life cycle of products is extended. In practice, it implies reducing waste to a minimum.”
(132)     The New European Innovation Agenda - European Commission
(133)    http://unep.org/resources/Global-Resource-Outlook-2024
(134)     https://www.kowi.de/Portaldata/2/Resources/heu/coop/he-built4people-sria-2022-27.pdf
(135)     https://circular-cities-and-regions.ec.europa.eu/support-materials/papers-and-reports . On this topic, see also the Urban Agenda for the EU https://ec.europa.eu/futurium/en/system/files/ged/sustainable_circular_reuse_of_spaces_and_buildings_handbook.pdf
(136)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(137)    ‘Health and well-being’ should in the context of this topic be understood in a comprehensive sense, comprising both mental and physical health and well-being.
(138)    See the 2019 WHO Scoping review “ What is the evidence on the role of the arts in improving health and well-being ?”
(139)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(140)    The European Commission defines social economy in the Communication ‘ Building an economy that works for people: an action plan for the social economy ’, COM(2021) 778 final, p. 5 "The social economy covers entities sharing the following main common principles and features: the primacy of people as well as social and/or environmental purpose over profit, the reinvestment of most of the profits and surpluses to carry out activities in the interest of members/users (“collective interest”) or society at large (“general interest”) and democratic and/or participatory governance. Traditionally, the term social economy refers to four main types of entities providing goods and services to their members or society at large: cooperatives, mutual benefit societies, associations (including charities), and foundations.” […
(141)    Among others, A. Costantini, Social Economy Enterprises and Cultural and Creative Industries. Observations and best practices, Bruxelles, Diesis 2018 CCIs-SEEs_-FINAL_2018.pdf
(142)     About the EU Social Economy Gateway - European Commission
(143) Economic and social impact of cultural and creative sectors | OECD    The Culture Fix. Creative people, places and industries (2022) Full Report | OECD ; Economic and social impact of cultural and creative sectors. Note for Italy G20 Presidency Culture Working Group
(144)    Promoting the social and solidarity economy for sustainable development A-77-L60.pdf
(145)    The 2021 study "Social mobility in the Creative Economy: Rebuilding and levelling up?" by the Creative Industries Policy and Evidence Centre (PEC) provides insights into class imbalances in the creative industries, highlights the need for systemic change to address deep-rooted structural inequalities in the creative industries and proposes a ten-point action plan for enhancing social mobility in the creative economy Social mobility in the Creative Economy: Rebuilding and levelling up?
(146)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(147) https://www.e-unwto.org/doi/epdf/10.18111/9789284418978    UN World Tourism Organization (2018), Tourism and Culture Synergies, p. 21.
(148)     https://hadea.ec.europa.eu/calls-proposals/data-space-tourism_en
(149)    This includes projects funded by Cluster 6 topic HORIZON-CL6-2024-COMMUNITIES-02-2-two-stage: New sustainable business and production models for farmers and rural communities.
(150)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(151)     https://commission.europa.eu/document/download/e6cd4328-673c-4e7a-8683-f63ffb2cf648_en?filename=Political%20Guidelines%202024-2029_EN.pdf
(152)     https://culture.ec.europa.eu/news/eurobarometer-publishes-findings-on-europeans-attitudes-towards-culture
(153)     Culture and democracy, the evidence - Publications Office of the EU
(154)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(155)     https://ich.unesco.org/en/convention
(156)    As defined in the EU Nature Restoration Regulation https://environment.ec.europa.eu/topics/nature-and-biodiversity/nature-restoration-regulation_en .
(157)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(158)    CCIs as defined in the European Parliament Resolution ‘A coherent EU policy for cultural and creative industries’: https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52016IP0486&from=EN
(159)     https://op.europa.eu/en/publication-detail/-/publication/6abcc8e7-e685-11ee-8b2b-01aa75ed71a1/language-en
(160)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A52021DC0101
(161)     https://www.ohchr.org/en/instruments-mechanisms/instruments/convention-rights-persons-disabilities
(162)    see topic HORIZON-CL2-2026-02-TRANSFO-01 in this Work Programme
(163)     https://ri-portfolio.esfri.eu/ for example CESSDA - Consortium of European Social Science Data Archives
(164)    With an additional three years to wind down, i.e. administer and report on FSTP projects launched with the last calls.
(165)    In line with rules for Horizon Europe on working with EU’s Decentralised Agencies.
(166)    Any eligible activity that is distinct from and complements the financial support to third parties/joint transnational calls and contributes to the objectives of the partnership.
(167)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(168)    Nature is an essential part of competitiveness. The Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) has demonstrated that around 55% of the global GDP is generated by sectors moderately to highly dependent on nature. Around 72% of euro area companies are critically dependent on ecosystem services.
(169)     https://commission.europa.eu/topics/eu-competitiveness/draghi-report_en
(170)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(171)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(172)    Cf. European Commission initiative on ‘A comprehensive approach to mental health’ or the call for evidence for an EU Action Plan Against Cyberbullying’.
(173)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(174)     https://commission.europa.eu/topics/eu-competitiveness/draghi-report_en
(175)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(176)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(177)     GreenComp , the European competence framework on sustainability, provides a conceptual model on the knowledge, skills and attitudes which support sustainability in a lifelong learning context.
(178)    https://www.cedefop.europa.eu/files/9197_en.pdf
(179)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(180)     https://home-affairs.ec.europa.eu/policies/migration-and-asylum/pact-migration-and-asylum_en
(181)    Integration should be understood as a two-way process.
(182)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(183)     See https://www.thcspartnership.eu/ or https://cordis.europa.eu/project/id/101095654
(184)     https://ri-portfolio.esfri.eu/ri-portfolio/table/
(185)     https://employment-social-affairs.ec.europa.eu/policies-and-activities/social-protection-social-inclusion/social-protection/long-term-care_en
(186)    DG JRC research activity on long-term care and demography aims to analyse the prevalence of neurodegenerative diseases (such as dementia) and implication on LTC demand and analysis of household composition (family structure changes) and implications on LTC provision.
(187)     https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/horizon-cl2-2022-transformations-01-10
(188)     https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/horizon-cl2-2023-transformations-01-08
(189)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(190)    SSH integration involves actively supporting interdisciplinary research and innovation that combines SSH with Science, Technology, Engineering, and Mathematics (STEM) to better address complex challenges such as climate change, public health issues, and technological innovation.
(191)     https://op.europa.eu/en/publication-detail/-/publication/2f9fc221-86bb-11ef-a67d-01aa75ed71a1/language-en
(192)    e.g. see the report ‘Integration of social sciences and humanities in Horizon 2020’ (https://op.europa.eu/en/publication-detail/-/publication/16b7df93-82b3-11ee-99ba-01aa75ed71a1/language-en) and the ‘Horizon Europe Integration’-report for 2021-2023 (https://op.europa.eu/en/publication-detail/-/publication/6cf8db13-62bb-11f0-bf4e-01aa75ed71a1/language-en).
(193)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(194)     https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A32024R1991&qid=1722240349976
(195)    The Green City Accord is a movement of European mayors committed to making cities cleaner and healthier. It aims to improve the quality of life for all Europeans and accelerate the implementation of relevant EU environmental laws. By signing the Accord, cities commit to addressing five areas of environmental management: air, water, nature and biodiversity, circular economy and waste, and noise. There are 119 signatory cities as of May 2025 ( https://environment.ec.europa.eu/topics/urban-environment/green-city-accord_en ).
(196)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(197)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(198)    The social economy covers entities sharing the following main common principles and features: the primacy of people as well as social and/or environmental purpose over profit, the reinvestment of most of the profits and surpluses to carry out activities in the interest of members/users (“collective interest”) or society at large (“general interest”) and democratic and/or participatory governance. Traditionally, the term social economy refers to four main types of entities providing goods and services to their members or society at large: cooperatives, mutual benefit societies, associations (including charities), and foundations. They are private entities, independent of public authorities and with specific legal forms. Social enterprises are now generally understood as part of the social economy. The social economy (associations, cooperatives, mutual societies, foundations, and social enterprises) provides monetary and non-monetary services, impacting on European sustainable competitiveness. Social economy actors also have a different approach to their working environment due to the societal objectives of their employers and the democratic governance of their ecosystems.
(199)    Nature is an essential part of competitiveness. The Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) has demonstrated that around 55% of the global GDP is generated by sectors moderately to highly dependent on nature. Around 72% of euro area companies are critically dependent on ecosystem services.
(200)     https://commission.europa.eu/document/download/e6cd4328-673c-4e7a-8683-f63ffb2cf648_en?filename=Political%20Guidelines%202024-2029_EN.pdf
(201)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(202)    See e.g. HORIZON-CL2-2022-TRANSFORMATIONS-01-02 - The impact of spatial mobility on European demographics, society, welfare system and labour market; https://publications.europa.eu/resource/cellar/a9351b1c-4d31-11ee-9220-01aa75ed71a1.0001.03/DOC_1 ; https://publications.europa.eu/resource/cellar/d697ee14-77ad-11ea-a07e-01aa75ed71a1.0001.01/DOC_1 ; https://cordis.europa.eu/project/id/727072 ; https://cordis.europa.eu/project/id/794030
(203)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(204)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(205)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(206)    Article 1 of the UN Convention on the Rights of Persons with disabilities: Persons with disabilities include those who have long-term physical, mental, intellectual or sensory impairments which in interaction with various barriers may hinder their full and effective participation in society on an equal basis with others. https://www.ohchr.org/en/instruments-mechanisms/instruments/convention-rights-persons-disabilities
(207)     https://op.europa.eu/en/publication-detail/-/publication/3e1e2228-7c97-11eb-9ac9-01aa75ed71a1/language-en
(208)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(209)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(210) The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The budget figures given in this table are rounded to two decimal places.
(211) The contribution from Cluster 2 for year 2027 is EUR 22.78 million for the Missions work programme part and EUR 4.06 million for the New European Bauhaus Facility work programme part.    The contribution from Cluster 2 for year 2026 is EUR 16.07 million for the Missions work programme part and EUR 2.96 million for the New European Bauhaus Facility work programme part.
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EN

Annex VI

Horizon Europe

Work Programme 2026-2027

6. Civil Security for Society

Table of contents

Introduction    

Calls    

Call - Civil Security for Society 2026    

Overview of this call    

Call - Civil Security for Society 2027    

Overview of this call    

Destinations    

Destination - Better protect the EU and its citizens against Crime and Terrorism    

HORIZON-CL3-2026-01-FCT-01: Improving capabilities of law enforcement to counter climate-related challenges    

HORIZON-CL3-2026-01-FCT-02: Open topic on preventing and countering the misuse of emerging technologies for criminal purposes, including issues related to lawful access to data    

HORIZON-CL3-2026-01-FCT-03: Missing persons: prevention and investigation    

HORIZON-CL3-2026-01-FCT-04: Crime prevention approaches, online and off-line, tackling the nexus between addictions and crime    

HORIZON-CL3-2026-01-FCT-05: Enhancing the security of citizens against terrorism and lone-actor violence in confined spaces such as schools    

HORIZON-CL3-2026-01-FCT-06: Prevention and mitigation of misuse of synthetic biology for bioterrorism purposes    

HORIZON-CL3-2027-01-FCT-01: Online harms detection and investigation tools using a short development cycle model    

HORIZON-CL3-2027-01-FCT-02: Community policing in diverse societies in Europe    

HORIZON-CL3-2027-01-FCT-03: Open topic on enhanced prevention, detection and deterrence of societal issues related to various forms of crime    

HORIZON-CL3-2027-01-FCT-04: Open topic on increasing security of citizens against terrorism, including in public spaces    

HORIZON-CL3-2027-01-FCT-05: Effective and evidence-based responses to the increased availability and use of synthetic drugs and stimulants in Europe    

Destination - Effective management of EU external borders    

HORIZON-CL3-2026-01-BM-01: Advanced border surveillance and situational awareness    

HORIZON-CL3-2026-01-BM-02: Accessible and available travel facilitation    

HORIZON-CL3-2026-01-BM-03: Reliability of age assessment methods in the context of security and border management    

HORIZON-CL3-2027-01-BM-01: Open topic on research and innovation for effective management of EU external borders that promotes fundamental rights and EU values    

HORIZON-CL3-2027-01-BM-02: Trusted, secure, quality future digital travel credentials    

HORIZON-CL3-2027-01-BM-03: Detection and characterisation of threats or illegal/ smuggled goods in cargo    

Destination - Resilient Infrastructure    

HORIZON-CL3-2026-01-INFRA-01: Tools and processes to support stress tests of critical infrastructure    

HORIZON-CL3-2026-01-INFRA-02: Security challenges of the green transition in urban und peri urban areas    

HORIZON-CL3-2026-01-INFRA-03: Targeted innovative capabilities for the resilience of critical entities to natural and human-induced disasters, including hybrid scenarios    

HORIZON-CL3-2027-01-INFRA-01: Enhancing physical protection of critical infrastructures    

HORIZON-CL3-2027-01-INFRA-02: Impact of malicious use of Open-Source Intelligence on critical infrastructure business continuity    

Destination - Cybersecurity    

Destination - Disaster-Resilient Society for Europe    

HORIZON-CL3-2026-01-DRS-01: Designing new ways of risk awareness and enhanced disaster preparedness    

HORIZON-CL3-2026-01-DRS-02: Multi-hazard approach and cumulative / cascading impacts    

HORIZON-CL3-2026-01-DRS-03: Development of innovative tools, processes, equipment and technologies through responses to disasters and emergencies for search and rescue in hazardous conditions    

HORIZON-CL3-2026-01-DRS-04: Open topic on driving innovation uptake of disaster risk solutions    

HORIZON-CL3-2026-01-DRS-05: Climate security and civil preparedness – new ways to develop pre- and post-crisis climate-change related scenarios for a more resilient Europe    

HORIZON-CL3-2027-01-DRS-01: Open Topic on advanced protective gear optimized for CBRN-E (Chemical, Biological, Radiological, Nuclear, Explosives) environments and new generation of smart protective equipment for disaster responders    

HORIZON-CL3-2027-01-DRS-02: Societal resilience, engagement of the younger generations and digital innovation for disaster resilience    

HORIZON-CL3-2027-01-DRS-03: Enhancing decision support system for disaster crises: leveraging emerging technologies for improved civil preparedness and crisis management    

HORIZON-CL3-2027-01-DRS-04: Enhancing preparedness for large-scale cross-border disasters    

Destination - Strengthened Security Research and Innovation    

HORIZON-CL3-2026-01-SSRI-01: Open topic on supporting disruptive technological innovations for civil security    

HORIZON-CL3-2026-01-SSRI-02: Demand-led innovation in security    

HORIZON-CL3-2026-01-SSRI-03: Public procurement of innovation for security    

HORIZON-CL3-2026-01-SSRI-04: Development of ecosystem and next-generation capabilities for a secured European Critical Communication System in civil security    

HORIZON-CL3-2027-01-SSRI-01: Accelerating uptake through open proposals for advanced SME innovation    

HORIZON-CL3-2027-01-SSRI-02: Open grounds for future pre-commercial procurement of innovative security technologies    

HORIZON-CL3-2027-01-SSRI-03: Demand-led innovation in security    

Other actions not subject to calls for proposals    

1. External expertise for reviews of projects    

2. Workshops, conferences, experts, communication activities, studies and innovation uptake promotion    

3. Indirectly Managed Action by the ECCC (2026)    

APPENDIX – Indirectly managed action by the ECCC 2026    

4. Indirectly Managed Action by the ECCC (2027)    

APPENDIX – Indirectly managed action by the ECCC 2027    

Budget    

Introduction

Cluster 3 provides a research and innovation response to a context of rapidly changing threats and challenges to internal security, the security of citizens, critical infrastructure and the security of society as a whole. These threats are driven by geopolitical, technological and societal changes, including:

1.Instability, hybrid threats and the resurgence of war on the European continent, in particular the Russian war against Ukraine, making the need for civilian protection, preparedness, and resilience.

2.Continued threat from terrorism and increased threat from organised crime.

3.The potential for large-scale movements of people, whether as a result of war, the instrumentalisation of migration or other drivers, require effective border management capabilities and further efforts to combat migrant smuggling, trafficking in Human Beings (THB), and possible terrorist infiltration.

4.More frequent and serious climate-related extreme events as well as other disasters, whether accidental or intentional, of human or natural origin, requiring disaster risk management and response.

5.Continued technological development and digitalisation create new and unforeseen vulnerabilities and new opportunities for criminals and violent extremists, as well as new challenges, needs and opportunities for security practitioners.

6.Cyber threats that put infrastructures, businesses, public administrations, and individuals at risk.

7.Negative socio-economic trends and climate adaptation that create potential for greater social polarisation and mistrust, which may escalate into conflict and/or create opportunities for extremists and malicious actors to spread hate speech and foreign information manipulation and interference and disinformation.

In addressing these and their related challenges, through research and innovation, this Work Programme will support the implementation of the new ProtectEU – European Internal Security Strategy 1 and European Preparedness Union Strategy 2 and the sectoral strategies, legislation and action plans identified in the Destinations.

Each Destination includes an introductory section that explains the relevant policy objectives, specifies elements to be taken into account for the topics of the Destination and identifies specific expected impacts. Proposals should set out a credible pathway to contribute to the specific expected impacts:

1.Better protect the EU and its citizens against Crime and Terrorism (FCT) 

Link to the Horizon Europe strategic plan 2025-2027: Expected impact 13 “Tackling crime and terrorism more effectively and increasing the resilience of infrastructures”.

1.Effective management of EU external borders (BM) 

Link to the Horizon Europe strategic plan 2025-2027: Expected impact 12 “Facilitating legitimate movement of passengers and goods into the EU, while preventing illicit acts”.

1.Resilient infrastructure (INFRA) 

Link to the Horizon Europe strategic plan 2025-2027: Expected impact 13 “Tackling crime and terrorism more effectively and increasing the resilience of infrastructures”.

1.Disaster-Resilient Society for Europe (DRS) 

Link to the Horizon Europe strategic plan 2025-2027: Expected impact 11 “Reducing losses from natural, accidental and human-made disasters”.

1.Strengthened Security Research and Innovation (SSRI) 

Link to the Horizon Europe strategic plan 2025-2027: Cross-cutting Destination that supports all the Expected impacts identified above.

In addition, under this Work Programme, the Commission intends to entrust implementation of a call for proposals to the European Competence Centre for Cybersecurity (ECCC). The call topics foreseen for this indirectly managed action (see Appendix to this Work Programme part) relate to:

1.Cybersecurity (CS) Link to the Horizon Europe strategic plan 2025-2027: Expected impact 14 “Increasing cybersecurity and making the online environment more secure”. 

Cluster 3 Work Programmes will support the implementation of the European Commission political guidelines 2024-2029 for a ‘Safer and more secure Europe’, a ‘Preparedness Union’, with ‘Stronger Common Borders’, protecting democracy and putting research and innovation at the heart of a resilient economy. Overall, research under this Cluster should continue to focus on preserving and securing citizens’ basic right to feel safe. Cluster 3 ‘civil security for society’ will therefore also support the Commission’s work:

1.the new European Internal Security Strategy, fighting organized crime and ensuring that security is integrated in EU legislation and policies by-design.

2.towards a European Civil Defence Mechanism, looking at all facets of crisis and disaster management, along community resilience building.

3.to provide practitioners, law enforcement authorities including customs fand border guards, first and second responders, critical infrastructure operators, with adequate and up-to-date tools for lawful access to digital information, while safeguarding fundamental rights.

4.to strengthen European competitiveness and make better use of public procurement and in particular support innovation procurement.

Successful projects need to show their understanding of and contribution to a wider innovation cycle based on a needs-driven capability development approach that triggers research, steers its implementation and capitalises on its outcomes. This means that projects need to show, on the one hand, an understanding of the capability requirement and policy context that has led to the R&I need, and, on the other hand, a strategy for ensuring the uptake of the outcomes including opportunities where relevant for using EU funds for deployment.

Eligibility to participate is also subject to the ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility condition (see General Annex B of the General Annexes).

Cross-cutting themes

Various themes run through this Work Programme, cutting across the different sectoral Destinations. A first set of themes respond to the wider challenges identified in the three key strategic orientations of the Horizon Europe strategic plan 2025-2027:

1.Strengthening resilient societies and democracy. The central focus of Cluster 3 is to support through research and innovation, the prevention, preparedness and response to the wide range of threats to internal security identified above, as well as ensuring the security of all citizens, critical infrastructure, supply chains and of society as a whole. Strengthening our democracies and making them more resilient – both materially and psychologically – has taken on a new urgency since the full-scale Russian invasion of Ukraine. European citizens need to be protected from hybrid threats such as disinformation and foreign information manipulation and interference campaigns while upholding the rule of law and basic freedoms, including freedom of speech. Civil security research and innovation needs to equip civil security practitioners, such as law enforcement, with the ability to mitigate the consequences of armed conflict, in particular attacks on critical infrastructures. By funding research to strengthen and prepare our societies, democracies, and infrastructure against hybrid threats, Cluster 3 shows its ability to adapt to changing conditions and challenges and mitigate the consequences of armed conflict, in particular attacks on critical infrastructures. By funding research to strengthen and prepare our societies, democracies, and infrastructure against hybrid threats, Cluster 3 shows its ability to adapt to changing conditions and challenges.

2.Securing the digital transition. The more widespread and ubiquitous digital technology is, the greater the threats of new and unforeseen vulnerabilities and new opportunities for criminals and violent extremists as well as new challenges, needs and tools for law enforcement authorities, infrastructures, businesses and individuals. Research on cybercrime and cybersecurity helps to address these matters. With the aim of creating a secure and trustworthy digital environment, Cluster 3 will invest in cybersecurity R&I to strengthen the EU’s resilience, protect its infrastructures and improve its ability to cope with cyber incidents. This will help increase the EU’s open strategic autonomy in cybersecurity. Cluster 3 addresses cybercrime and the developing security threats in a digital age, such as criminal use of AI, to protect people, institutions and companies against cyber-enabled crimes. It will also continue to harness the opportunities of new technologies for law enforcement, border management and disaster risk reduction and uphold the ability of the law enforcement to lawfully access and exploit digital evidence, without compromising or weakening privacy safeguards or cybersecurity.

3.Supporting the green transition in civil security. Climate change and environmental degradation are increasingly recognised as threat multipliers. Climate-related extreme events such as floods, droughts and forest fires pose increasing threats to people, nature business and infrastructure. Geological hazards such as earthquakes, volcanic eruptions, and tsunamis are also threats affecting security. As EU Member States and Associated Countries face similar challenges, including varied and evolving transnational disasters, Cluster 3 will develop solutions to be applied throughout the EU to keep up to date with the developments. Cluster 3 will also address environmental crime. It will help understand how to manage borders in case of potential large-scale movements of people, including those caused by environmental stress. It will promote environmental sustainability of security solutions.

A second set of cross-cutting themes respond to challenges more specific to Cluster 3:

1.Ensuring legal and ethical outcomes that are supported by society. Ethics, respect for the rule of law, fundamental rights, including human rights, privacy and the protection of personal data, as well as responsible research, must be at the heart of security research. Citizens and communities, including women and underrepresented groups, should be engaged, for example in assessing the societal impact of security technologies, to improve the quality of results and to build public trust. Social sciences and humanities (SSH) and social innovation need to be appropriately integrated into security research. The aim is to develop an inclusive set of civilian security solutions that are as minimally intrusive as possible while respecting freedoms, rights and values.

2.Protecting and empowering disadvantaged groups or in a vulnerable situation. A range of groups are disproportionately exposed to violence and threats towards their security. These include, women, LGBTIQ people, ethnic, racial or religious minorities, persons with a migrant background, persons with disabilities 3 , persons living with chronic illnesses, older people and children. The vulnerability of these groups is further exacerbated by factors such as insecure supply chains for essential medicines which can be disrupted by disasters or criminal activities. The needs and rights of travellers, migrants, and refugees must be protected and promoted in border management activities. Unfortunately, these groups are also at a higher risk of falling victim to trafficking in human beings. Research under Cluster 3 needs to consider how these groups can be better protected, including by analysing the structures that foster violence against these groups, developing measures to tackle violence, and promoting inclusive and empowering approaches that prioritise the needs and the rights of disadvantaged groups or in a vulnerable situation.

3.Improving market uptake of civil security research solutions. Despite many success stories of tools and capabilities used by security practitioners originating from EU-funded security research projects, the uptake and deployment of successful research results remains a constant challenge. This challenge spans all destinations.

This Work Programme:

1.continues the Cluster 3 practice of requiring projects to involve security practitioners, such as law enforcement, alongside researchers and industry. Such involvement has shown its added value in ensuring that tools, technologies and capabilities are developed for the benefit of and use by end-users and practitioners;

2.strengthens this involvement by introducing in many topics a requirement that proposals should plan a mid-term deliverable where practitioners involved in the project assess the project’s mid-term outcomes;

3.innovation procurement is used under the SSRI destination, this year with the open grounds preparatory work for future Pre-Commercial Procurement (PCP) topic, to bridge the gap between research, innovation and deployment, and thus strengthen the European market and European civil security industrial base;

4.encourages synergies with other EU funding programmes and instruments to enable or facilitate the uptake of the results of research into deployable solutions. Further information about this is given below.

5.the possibilities and support of security end-users like FRONTEX, EUROPOL, EU-LISA, the EU Drugs Agency and the proposed EU Customs Authority (in the context of the Customs Reform), for testing and validation of security research results should be used and expanded to the fullest extent.

6.supports projects which can directly or indirectly support public institutions intent on setting up their own innovation processes, which is to be encouraged.

7.encourages a competitive and innovative market, accessible for small and medium-sized enterprises (SMEs).

Where relevant, Cluster 3 will make use of space technology and Earth Observation.

A third set of cross-cutting themes address the need for greater simplification and research and innovation funding in support of the EU’s competitiveness:

1.Strengthening European competitiveness. Growing challenges, such as climate change, artificial intelligence and geopolitical tensions are changing the world we live in. It is therefore paramount that Europe is a place where growth and innovation continue to be fostered. To do so, competitiveness has been placed at the heart of the EU’s economic agenda. The Commission’s work in this area is guided by the Competitiveness Compass and the Draghi report. Cluster 3 will contribute to increasing Europe’s competitiveness through research and innovation projects which contribute to the development of key technologies, reduce dependencies and further strategic autonomy, increase resilience and security, and preserve and secure citizens’ basic right to feel safe.

2.Increased simplification. In order to simplify applying for funding and taking part in the programme certain measures have been applied, these include topics that are more open and adequately prescriptive, and the application of lump sum funding.

International cooperation

Cluster 3 continues to require a specific approach to international cooperation to achieve the right balance between the benefits of exchange with key international partners, while ensuring the protection of the EU’s security interests and the need for strategic autonomy in critical sectors.

Under the destination ‘Disaster-Resilient Society for Europe’ (DRS), there is an established culture of comprehensive research collaboration with non-EU countries, taking account of the transnational aspect of different natural and human-made hazards and their causes (such as climate change). Therefore, under this destination, international cooperation is strongly encouraged, given the value of international cooperation, especially in developing technologies for first responders.

For the destinations relating to border management, the fight against crime and terrorism, infrastructure resilience and cybersecurity, international cooperation will be explicitly encouraged only where appropriate and specifically supportive of ongoing collaborative activities.

Synergies with other EU funding programmes and instruments

Cluster 3 will continue building and facilitating synergies with other EU funding programmes and instruments, in an approach with long-term capability development planning at its core. This is particularly important for civil security, where solutions are often demand-driven in a market that tends to be narrow, institutional, highly regulated, sensitive, and often fragmented along national lines.

From the demand side (funding for security practitioners and authorities, who are the users of security solutions), Cluster 3 will continue to operationalise the synergies with the home affairs funds: the Internal Security Fund (ISF) and the Integrated Border Management Fund (IBMF) in its two components, the Border Management and Visa Instrument (BMVI) and the Customs Control Equipment Instrument (CCEI). This will mean both facilitating the uptake of the results of Cluster 3 research by Member States and Associated Countries in their national programmes, and programming EU and specific actions with funding dedicated to taking up innovation resulting from Cluster 3 research.

In addition to the home affairs funds, Cluster 3 will continue promoting synergies with the Digital Europe Programme, the European Maritime Fisheries and Aquaculture Fund (EMFAF), the Union Civil Protection Mechanism (Knowledge for Action in Prevention and Preparedness calls for proposals, rescEU grants, early warning capabilities, and the training and exercises programme), the Copernicus Service for Security (CSS), the European Regional Development Fund (ERDF), the Cohesion Fund, the Neighbourhood, Development and International Cooperation Instrument – Global Europe instrument for the Southern and Eastern Neighbourhood and the Instrument for Pre-Accession, the Technical Support Instrument (TSI), the OLAF Union Anti-Fraud Programme (UAFP) and EU4Health.

From the supply side (funding for European innovators who develop and commercialise security solutions), the promotion of the uptake of the results of Cluster 3 research could involve the Innovation Fund and, to a lesser extent, EU actions under the ISF and the BMVI, as well as Health Emergency Preparedness and Response HERA Invest and the European Institute of Innovation and Technology (EIT).

Practical ways in which Cluster 3 will continue to improve and promote synergies include raising Member States’ and Associated Countries authorities’ and innovators’ awareness of the opportunities for funding for uptake in other EU programmes and instruments, and tracking and studying uptake of Cluster 3 projects’ results in other EU programmes and instruments; planning actions in other EU funding programmes and instruments to fund innovation in civil security that takes up the results of Cluster 3 research.

Research funded under Cluster 3 will continue to focus exclusively on civilian applications. Coordination with the European Defence Fund (EDF) and the EU Space Programme will be sought to strengthen cross-cluster complementarities also with actions foreseen in particular in Horizon Europe Clusters 2 and 4 4 .

Role of the Justice and Home Affairs (JHA) agencies

EU JHA agencies and in particular Europol 5 , Frontex 6 and eu-LISA 7 take on a particular role in Horizon Europe. They assist the European Commission on relevant research and innovation activities and on specific topics that they identify as desirable to be involved after grants have been awarded.

Proposals should foresee that JHA agencies could observe projects’ pilots and demonstrations, with the aim of facilitating future uptake of innovations for the civil security research community.

EU JHA agencies are, however, not eligible to participate in any proposal preparation phase and should not be contacted and no documentation should be sent by applicants/consortium members before grants have been awarded.

Similarly, if the proposals concern drug-related issues, successful projects are expected to engage with the European Union Drugs Agency (EUDA) during the lifetime of the project, including validating the outcomes.

For aspects of training of Police Authorities, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding.

Implementation

Proposals under certain topics in this Work Programme should plan their activities opting for the Financial Support to Third Parties (FSTP) 8 .

Calls

Call - Civil Security for Society 2026

HORIZON-CL3-2026-01

Overview of this call 9

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 10

Indicative number of projects expected to be funded

2026

Opening: 06 May 2026

Deadline(s): 05 Nov 2026

Destination - Better protect the EU and its citizens against Crime and Terrorism

HORIZON-CL3-2026-01-FCT-01: Improving capabilities of law enforcement to counter climate-related challenges

RIA

8.00

Around 4.00

2

HORIZON-CL3-2026-01-FCT-02: Open topic on preventing and countering the misuse of emerging technologies for criminal purposes, including issues related to lawful access to data

RIA

9.00

Around 4.50

2

HORIZON-CL3-2026-01-FCT-03: Missing persons: prevention and investigation

IA

5.00

Around 5.00

1

HORIZON-CL3-2026-01-FCT-04: Crime prevention approaches, online and off-line, tackling the nexus between addictions and crime

RIA

6.00

Around 3.00

2

HORIZON-CL3-2026-01-FCT-05: Enhancing the security of citizens against terrorism and lone-actor violence in confined spaces such as schools

IA

9.67

Around 4.835

2

HORIZON-CL3-2026-01-FCT-06: Prevention and mitigation of misuse of synthetic biology for bioterrorism purposes

RIA

3.00

Around 3.00

1

Destination - Effective management of EU external borders

HORIZON-CL3-2026-01-BM-01: Advanced border surveillance and situational awareness

IA

12.00

Around 6.00

2

HORIZON-CL3-2026-01-BM-02: Accessible and available travel facilitation

IA

8.00

Around 4.00

2

HORIZON-CL3-2026-01-BM-03: Reliability of age assessment methods in the context of security and border management

CSA

1.33

Around 1.33

1

Destination - Resilient Infrastructure

HORIZON-CL3-2026-01-INFRA-01: Tools and processes to support stress tests of critical infrastructure

IA

9.67

Around 4.835

2

HORIZON-CL3-2026-01-INFRA-02: Security challenges of the green transition in urban und peri urban areas

RIA

4.00

Around 4.00

1

HORIZON-CL3-2026-01-INFRA-03: Targeted innovative capabilities for the resilience of critical entities to natural and human-induced disasters, including hybrid scenarios

IA

9.00

Around 4.50

2

Destination - Disaster-Resilient Society for Europe

HORIZON-CL3-2026-01-DRS-01: Designing new ways of risk awareness and enhanced disaster preparedness

RIA

6.00

Around 3.00

2

HORIZON-CL3-2026-01-DRS-02: Multi-hazard approach and cumulative / cascading impacts

IA

8.00

Around 4.00

2

HORIZON-CL3-2026-01-DRS-03: Development of innovative tools, processes, equipment and technologies through responses to disasters and emergencies for search and rescue in hazardous conditions

IA

8.00

Around 4.00

2

HORIZON-CL3-2026-01-DRS-04: Open topic on driving innovation uptake of disaster risk solutions

IA

6.00

Around 3.00

2

HORIZON-CL3-2026-01-DRS-05: Climate security and civil preparedness – new ways to develop pre- and post-crisis climate-change related scenarios for a more resilient Europe

IA

4.50

Around 4.50

1

Destination - Strengthened Security Research and Innovation

HORIZON-CL3-2026-01-SSRI-01: Open topic on supporting disruptive technological innovations for civil security

RIA

3.00

Around 1.50

2

HORIZON-CL3-2026-01-SSRI-02: Demand-led innovation in security

PCP

5.83

Around 5.83

1

HORIZON-CL3-2026-01-SSRI-03: Public procurement of innovation for security

PPI

2.00

Around 2.00

1

HORIZON-CL3-2026-01-SSRI-04: Development of ecosystem and next-generation capabilities for a secured European Critical Communication System in civil security

IA

3.00

Around 3.00

1

Overall indicative budget

131.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - Civil Security for Society 2027

HORIZON-CL3-2027-01

Overview of this call 11

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 12

Indicative number of projects expected to be funded

2027

Opening: 05 May 2027

Deadline(s): 04 Nov 2027

Destination - Better protect the EU and its citizens against Crime and Terrorism

HORIZON-CL3-2027-01-FCT-01: Online harms detection and investigation tools using a short development cycle model

IA

7.83

Around 7.833

1

HORIZON-CL3-2027-01-FCT-02: Community policing in diverse societies in Europe

IA

6.00

Around 3.00

2

HORIZON-CL3-2027-01-FCT-03: Open topic on enhanced prevention, detection and deterrence of societal issues related to various forms of crime

RIA

6.00

Around 3.00

2

HORIZON-CL3-2027-01-FCT-04: Open topic on increasing security of citizens against terrorism, including in public spaces

IA

9.00

Around 4.50

2

HORIZON-CL3-2027-01-FCT-05: Effective and evidence-based responses to the increased availability and use of synthetic drugs and stimulants in Europe

IA

8.00

Around 4.00

2

Destination - Effective management of EU external borders

HORIZON-CL3-2027-01-BM-01: Open topic on research and innovation for effective management of EU external borders that promotes fundamental rights and EU values

RIA

8.00

Around 4.00

2

HORIZON-CL3-2027-01-BM-02: Trusted, secure, quality future digital travel credentials

RIA

8.00

Around 4.00

2

HORIZON-CL3-2027-01-BM-03: Detection and characterisation of threats or illegal/ smuggled goods in cargo

RIA

14.00

Around 3.50

4

Destination - Resilient Infrastructure

HORIZON-CL3-2027-01-INFRA-01: Enhancing physical protection of critical infrastructures

IA

12.00

Around 6.00

2

HORIZON-CL3-2027-01-INFRA-02: Impact of malicious use of Open-Source Intelligence on critical infrastructure business continuity

IA

7.67

Around 3.835

2

Destination - Disaster-Resilient Society for Europe

HORIZON-CL3-2027-01-DRS-01: Open Topic on advanced protective gear optimized for CBRN-E (Chemical, Biological, Radiological, Nuclear, Explosives) environments and new generation of smart protective equipment for disaster responders

IA

7.67

Around 3.835

2

HORIZON-CL3-2027-01-DRS-02: Societal resilience, engagement of the younger generations and digital innovation for disaster resilience

RIA

6.00

Around 3.00

2

HORIZON-CL3-2027-01-DRS-03: Enhancing decision support system for disaster crises: leveraging emerging technologies for improved civil preparedness and crisis management

IA

9.00

Around 3.00

3

HORIZON-CL3-2027-01-DRS-04: Enhancing preparedness for large-scale cross-border disasters

IA

8.00

Around 4.00

2

Destination - Strengthened Security Research and Innovation

HORIZON-CL3-2027-01-SSRI-01: Accelerating uptake through open proposals for advanced SME innovation

IA

4.50

Around 1.50

3

HORIZON-CL3-2027-01-SSRI-02: Open grounds for future pre-commercial procurement of innovative security technologies

CSA

2.00

Around 1.00

2

HORIZON-CL3-2027-01-SSRI-03: Demand-led innovation in security

PCP

5.83

Around 5.83

1

Overall indicative budget

129.50

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Destinations

Destination - Better protect the EU and its citizens against Crime and Terrorism

As underlined in the Horizon Europe strategic plan 2025-2027, “this Destination will support the Commission’s priorities by addressing new, upcoming or unforeseen challenges and/or creative or disruptive solutions for improving the prevention, detection and deterrence of various forms of crime or terrorism/radicalisation through an enhanced understanding of the related societal issues. In doing so, research and innovation projects funded under cluster 3 will contribute to safeguarding, sustaining, and improving the Union’s unique quality of life, by improving the Union’s ability to prevent, detect, and deter various forms of crime and terrorism, including the different forms of hybrid threats and gender-based violence, in a proportional and human rights-compliant manner. Research under this Destination will contribute to the forthcoming Internal Security Strategy and Counter-Terrorism Agenda”.

This destination will support the implementation of the European Commission political guidelines 2024-2029 for a ‘Safer and more secure Europe’ as well as of ProtectEU 13 – a European Internal Security Strategy to support Member States and bolster the EU's ability to guarantee security for its citizens, and the Preparedness Union Strategy to support Member States and enhance Europe's capability to prevent and respond to emerging threats. Overall, research under this Cluster should continue to focus on preserving and ensuring citizens’ basic right to feel secure. This destination will also support the European Commission efforts towards a new Counter-Terrorism Agenda to address new and emerging threats, and a united approach to security, centred around a new European Critical Communication System to be used by public authorities in charge of security and safety.

To this end, proposals should contribute to the achievement of one or more of the following impacts:

1.Modern information analysis for Police Authorities, allowing them to efficiently fight criminals and terrorists who use novel technologies;

2.Improved forensics and lawful evidence collection, increasing the capabilities to apprehend criminals and terrorists and bring them to the court;

3.Enhanced prevention, detection and deterrence of societal issues related to various forms of crime, including cybercrime, and terrorism, such as violent radicalisation, as well as domestic sexual violence, and gender-based violence, with a particular emphasis on protecting populations in a vulnerable situation and victims at increased risk of violence, including those affected by child sexual abuse and juvenile delinquency;

4.Increased security of citizens against terrorism, including in public spaces (while preserving their quality and openness);

5.Improved intelligence picture and enhanced prevention, detection and deterrence of various forms of organised crime;

6.More secure cyberspace for citizens, especially children and elderly people, through a robust prevention, detection, and protection from cybercriminal activities.

More specifically, in the rapidly evolving technological and societal landscape, with climate change and environmental aspects increasingly seen as security issues, and with growing threats to citizens in a vulnerable situation, various forthcoming challenges that European society faces deserve dedicated research and innovation actions in the scope of this Destination. Some of them are:

1.challenges regarding prevention, detection and deterrence of various forms of crime and terrorism through an enhanced understanding of the related societal issues, such as

1.tackling the nexus between disinformation, hate speech and radicalisation, countering gender-based violence, or fighting violence-as-a-service.

2.challenges related to counterterrorism, protection of public spaces, such as

1.improving detection of remote explosives and explosives in closed spaces and urban environments, or

2.use and countering of unmanned systems, including neutralisation of commercial drone attacks.

Research and innovation funded under this Destination will contribute to policy objectives such as those of the:

1.Police cooperation package 14 (information exchange 15 , automated data exchange for police cooperation - “Prüm II” 16 , operational cross-border police cooperation 17 );

2.Counter-Terrorism Agenda for the EU 18 (incl. Regulation 2021/784/EU on addressing dissemination of terrorist content online & Directive 2017/541/EU on combating terrorism);

3.EU C-UAS Strategy 19 (counter-drone policy);

4.EU Strategy to Tackle Organised crime 20 ;

5.EU Strategy on combatting Trafficking in Human Beings 21 (the modified Directive on preventing and combating trafficking in human being and protecting its victims), and the Proposal to strengthen EU legislation to prevent and fight migrant smuggling 22 (notably its aspect of reinforcing Europol’s role in the fight against migrant smuggling and trafficking in human beings);

6.EU drugs measures (Strategy 23 , Action Plan 24 and Roadmap to fight Drugs Trafficking and Organised Crime 25 );

7.EU Action Plan on firearms trafficking (COM(2020) 608 final);

8.Roadmap for lawful and effective access to data for law enforcement (COM/2025/349 final);

9.EU environmental crime measures 26 (review of the Directive 2008/99/EC on protection of the environment through criminal law);

10.EU anti-corruption measures (Communication 27 , proposal for a Directive 28 );

11.Directive (EU) 2019/713 on non-cash means of payment;

12.EU strategy on a more effective fight against child sexual abuse 29 (incl. Proposal for a regulation to prevent and combat child sexual abuse 30 );

13.EU Regulation (2022/2371) on serious cross-border threats to health;

14.Directive (EU) 2024/1385 on combating violence against women and domestic violence.

This Destination will also support, whenever appropriate and applicable, proposals with:

1.a clear strategy on how they will adapt to the fast-evolving environment in the area of fight against crime and terrorism (evolution of related technologies, evolution of criminal modi operandi and business models related to these technologies, etc.);

2.the involvement of Police Authorities in their core;

3.the involvement of other law enforcement authorities including customs and border guards;

4.the active role for Non-Governmental Organisations (NGOs) and Civil Society Organisations (CSOs);

5.the active involvement of Small and Medium Enterprises (SMEs);

6.a minimum-needed platform, i.e., tools that are modular and can be easily plugged into another platform (in order to avoid platform multiplication);

7.tools that are developed and validated against practitioners’ needs and requirements;

8.tools following existing or new standards for data exchange, including cybersecurity best-practices;

9.a robust plan on how they will build on the relevant predecessor projects;

10.education and training aspects, especially for Police Authorities and other relevant practitioners, as well as information sharing and citizen awareness raising;

11.a clear strategy on the uptake and sustainability of the project results, with special attention to the access at little or no cost to created tools and methodologies by Police Authorities involved in the project;

12.a well-developed plan both on how research data for training and testing will be obtained, in order to reach the requested Technology Readiness Levels (TRLs), and on how the specific TRL will be measured.

For Police Authorities’ training-related aspects, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding. Where possible and relevant, synergy-building and clustering initiatives with successful proposals in the same area should be considered, in coordination with the Community for European Research and Innovation for Security (CERIS) 31 .

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Proposals are invited against the following topic(s):

HORIZON-CL3-2026-01-FCT-01: Improving capabilities of law enforcement to counter climate-related challenges

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Police Authorities 32 from at least 2 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 33 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Police Authorities in Europe are equipped with specialised skills and technologies to counter an increase in illegal activities related to the climate change and the emergence of new (opportunistic) criminal patterns;

2.Improved understanding by policymakers of the effects of climate change on law enforcement with a view of developing related effective European policies;

3.improved knowledge of the impacts of climate change phenomena on social dynamics which can raise demands from public authorities to keep public order, moving beyond traditional perspectives about crime and terrorism.

Scope: Global climate change is a megatrend expected to affect our societies over the next decade. As stated in “Germany: National interdisciplinary climate risk assessment” 34 , “We are already living in the climate crisis. This brings substantial security risks at global and national levels. (...) Anyone thinking about security needs to think about climate as well”.

Climate change will affect European law enforcement in various ways 35 , 36 . Notably, it is likely to create new opportunities and resources for organised crime, challenging current security frameworks. One of the expected outcomes of climate change will be the emergence of scarcity markets. Links between resource scarcity propelled by climate change and the crime opportunities for organised crime groups need to be further analysed. Criminal networks will aim to dominate the scarcity markets, increasing their role in the distribution of essential goods and services such as food and water. In addition, criminal networks will facilitate the movement of migrants, including women and children, escaping conflict and the effects of climate change; increased flux of migration due to extreme weather conditions may raise opportunities for human trafficking and exploitation. Furthermore, the decline in biodiversity will translate into more animal species under threat of extinction targeted by wildlife traffickers. In this landscape, the adoption of new technologies will bolster criminal organizations of various kinds. Examples of such crimes, illegal activities, threats and harms connected to climate change include: environmental crimes contributing to climate change (illegal mining and extraction, illegal use of underwater sources and streams, illegal deforestation, illegal waste management), wildlife trafficking and poaching, fraud and financial crimes (greenwashing, carbon credit fraud, misuse of climate funds), exploiting climate change-related disasters (water theft, looting after disasters, land grabbing), or social tensions (new forms of radicalisation and terrorism, increased displacement and migration challenging public order and disproportionately affecting groups in a vulnerable situation).

New approaches centred around crime and climate change, including crime activities’ association with and amplification by climate change, present unique challenges that require thorough investigation and analysis. Recognizing these emerging trends is vital for formulating effective plans and policies, and equipping law enforcement with specialized skills, technology (including forensics) and training necessary to tackle these challenges in an increasingly volatile world.

In this topic, apart from the mandatory participation of Police Authorities in the consortia, active involvement of other security practitioners, such as civil security services, Border Guard or Customs Authorities, is encouraged if relevant. Technological and societal angles should be addressed in a balanced way.

Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. Proposals funded under this topic are expected to provide ideas on how they would engage with the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community. For Police Authorities’ training-related aspects, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding. Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

This topic requires the effective contribution of Social Sciences and Humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities. Research in this area could be strengthened by considering the gender-specific dimensions of vulnerabilities and needs when relevant.

HORIZON-CL3-2026-01-FCT-02: Open topic on preventing and countering the misuse of emerging technologies for criminal purposes, including issues related to lawful access to data

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 9.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Police Authorities 37 from at least 2 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

Subject to restrictions for the protection of European communication networks.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 38 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes:

1.Police Authorities in Europe are empowered with modern, accessible and validated tools, methodologies and training curricula to anticipate and cope with the misuse of new and emerging technologies for criminal purposes, with the aim to facilitate prevention, detection, efficient data access and investigation of criminal offences in a lawful manner and with full respect of fundamental rights, including the right to protection of personal data and to privacy;

2.Reinforced interdisciplinary collaboration at the European level through the establishment of partnerships among technologists, policymakers and Police Authorities, resulting in a holistic understanding of the challenges posed by emerging technologies and in sharing of best practices;

3.Clear guidelines and frameworks are created, including on procedures and rules, that ensure lawful access to data, balancing the needs of security with respect for privacy and that foster a European approach to the related challenges for the police and the judiciary.

Scope: New and emerging technologies (e.g., new communication technologies, quantum technologies, new biometrics and identification technologies, cloud computing technologies, generative AI etc.) bring many benefits but also pose a number of new challenges for the police and the judiciary. Therefore, there is a strong need to adequately tackle challenges for Police Authorities stemming from all these new and emerging developments as well as to make sure that the lawful access to data keeps track with these evolutions, respecting applicable legislation and fundamental rights such as personal data protection and privacy.

Under the Open topic, proposals are welcome to address new and emerging technologies that are not covered by the other projects of the previous Horizon Europe Calls Fighting Crime and Terrorism, as well as of the current Call Fighting Crime and Terrorism 2026-2027. Proposals should emphasize adaptive methodologies and frameworks that can evolve in response to new threats and challenges, empowering Police Authorities to act effectively while ensuring adherence to legal standards regarding data access. Thus, research activities proposed within this topic should, in a balanced way, 1) develop modern tools, methodologies and training material for police to tackle the problem of misuse for criminal purposes of the new and emerging technologies under consideration, and 2) address issues related to lawful access to data in this context.

In this topic the integration of the gender and intersectional dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement. Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact.

The proposals funded under this topic that concern issues which are within the mandate of Europol 39 are expected to engage with the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community. Similarly, if the proposals concern drug-related issues, they are expected to engage with the EU Drugs Agency during the lifetime of the project, including validating the outcomes. For Police Authorities’ training-related aspects, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding.

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

HORIZON-CL3-2026-01-FCT-03: Missing persons: prevention and investigation

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 3 Police Authorities 40 and at least 2 Civil Society Organisations (or Non-Governmental Organisations) from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 41 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Improved skills, tools and training curricula for Police Authorities in Europe and Civil Society Organisations (or Non-Governmental Organisations) to work with at-risk groups to prevent persons from going missing. Those improved skills, tools and training curricula are to take into account European multicultural dimension, as well as legal and ethical rules of operation;

2.Enhanced investigation tools and methodologies for Police Authorities in Europe to tackle cold cases in the context of missing persons, based on modern (forensic) technologies and criminology;

3.Modern training curricula for Police Authorities, their improved cross-border cooperation and enhanced tools and methodologies to tackle new cases of missing persons;

4.Enriched European common approaches applied by Police Authorities in Europe to fight the issue of missing persons relying on the synergy of technology, the latest socio-psychological knowledge learned from cases, as well as field experience of Police Authorities and entities dealing with victims, while fully respecting fundamental rights such as privacy, protection of personal data and anonymity of victims.

Scope: The issue of missing persons is a multifaceted challenge that encompasses diverse categories and is influenced by various factors. People may go missing under a variety of circumstances, such as voluntary disappearances, abductions, cases related to mental health crises, or because of conflict, migration, geopolitical instability, natural disasters. Groups in a vulnerable situation - notably children, victims of trafficking and exploitation, persons with disabilities and persons suffering from cognitive impairments - face an even greater risk of going missing, often under distressing and dangerous conditions. Tackling this issue requires a coordinated response from multiple stakeholders, from Police Authorities via Civil Society Organisations (CSOs) or Non-Governmental Organisations (NGOs) to the involvement of the overall society.

In an era of rapid technological advancement and societal developments, there is a pressing need to improve current European approaches to fight the issue of missing persons (prevention and/or investigation of cold and new cases) using innovative societal and technological solutions. To this end, modernised skills, training curricula and methodologies for Police Authorities, CSOs and NGOs to work with people in a vulnerable situation and children are needed, such as effective awareness raising campaigns, which should be accessible to persons with disabilities, that take into account European multicultural dimension. When it comes to investigation, Police Authorities need efficient tools that benefit from new and emerging technologies to solve cold cases while combining modern forensic science (including biometrics and digital forensics) and criminology, e.g., modern tools for using an old DNA, or accurate facial ageing, among others. When multiple practitioners are involved in exchanging sensitive data, data sharing tools in a privacy-preserving manner should be considered. Furthermore, for new cases of missing persons, apart from an improved cross-border cooperation, Police Authorities also need, on the one hand, a modernised training to face such situations more efficiently, improving the dialogues and interactions with families, taking into account a gender sensitive and intersectional approach when relevant, and on the other hand, modern technologies and forensic tools for, for example, fast and reliable cross-matching of DNA samples between new and cold cases.

If a proposal concerns forensics, its consortium should involve forensic institutes as well. Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. Proposals funded under this topic are expected to provide ideas on how they would engage with the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community. For aspects of training of Police Authorities, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding. To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project. Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

HORIZON-CL3-2026-01-FCT-04: Crime prevention approaches, online and off-line, tackling the nexus between addictions and crime

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 6.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Police Authorities 42 and at least 2 Civil Society Organisations (or Non-Governmental Organisations) from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 43 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Improved understanding of links between addictions and crime, including drivers of criminality;

2.Innovative and effective solutions, including training curricula, for Police Authorities in Europe and relevant Civil Society Organisations (or Non-Governmental Organisations) to prevent addictions and related crimes, with a special attention to young people at risk;

3.Evidence-based support to modernising European criminal justice system’s approach when dealing with addiction-related offenses;

4.Novel approaches of collaboration between different stakeholders, primarily Police Authorities in Europe and Civil Society Organisations (or Non-Governmental Organisations), to increase communities’ addiction resilience, security and safety.

Scope: A close and complex relationship exists between addictions, such as gambling, drug or alcohol use, and crime (e.g., criminals are often under the influence of drugs while committing crimes, gamblers or drug users commit crimes to pay for their debts or drugs). In this topic, successful proposals are expected to analyse the specific nexus between addictions and crime, with the aim of developing related modern methodologies and tools for prevention of not only addictions but also crimes related to them, both offline and online, while respecting the fundamental rights of the communities concerned and using of non-stigmatising language. Novel approaches of collaboration between different community stakeholders, from Police Authorities, civil society, national and local entities, private actors, trained psychologists, are expected to be developed as well, with the aim of increasing communities’ addiction resilience, security and safety. An emphasis of the work should be on young people at risk, the criminal justice system, drivers of criminality and pathways from committing a petty crime because of addiction to progressively getting involved in organised crime. Activities proposed within this topic should address the issue from various angles, combining both social research with technological development and applications in a logical manner.

Therefore, this topic requires the effective contribution of Social Sciences and Humanities (SSH) disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities. Also, incorporating a gender-sensitive approach will allow to better understand the relationships between addiction, crime, and gender, leading to more effective interventions that address the specific needs of men, women, and marginalized groups.

Proposals should outline the plans to develop possible future uptake and upscaling at national and EU level for possible next steps once the project is finalised. Proposals should also consider, build on if appropriate and not duplicate previous research. Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact.

Furthermore, proposals funded under this topic are expected to provide ideas on how they would engage with the European Union Drugs Agency (EUDA) during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations. For aspects of training of Police Authorities, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding. Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

HORIZON-CL3-2026-01-FCT-05: Enhancing the security of citizens against terrorism and lone-actor violence in confined spaces such as schools

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.835 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 9.67 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 3 Police Authorities 44 and at least 2 Civil Society Organisations (or Non-Governmental Organisations) from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 45 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Increased understanding of policymakers and relevant security practitioners of the phenomenon of terrorism and lone-actor violence towards citizens in confined places such as schools, in the European context;

2.Terrorist and lone-actor attacks to citizens in confined places such as schools, are prevented in Europe by, e.g., detecting and tackling early signs of isolation and radicalisation, as well as the promotion of a secure and inclusive environment;

3.European schools and other confined places, e.g., places of worship, public administration or other buildings accessible to the public, are provided with state-of-the-art means of ensuring their security;

4.Cooperation between Police Authorities in Europe and relevant staff (in schools, public administration, etc.) is improved.

Scope: Citizens in European schools and other confined spaces (e.g., places of worship, public administration and other buildings accessible to the public) increasingly face various forms of terrorism and lone-actor violence. This topic aims at providing such places with solutions for ensuring civil security (of pupils, school staff, administrative workers, citizens at large) via exploring various societal and technological means of preventing such threats, with full respect of fundamental rights, such as rights to privacy and the protection of personal data. Based on a thorough analysis of the phenomenon under consideration in the European context, proposals should look into methodologies of catching and tackling early signs of terrorist threats, isolation and radicalisation, taking into account the social and cultural factors that may influence an individual's vulnerability to radicalisation, such as gender roles and stereotypes. Proposals should also consider how these factors may impact the effectiveness of prevention programmes and of addressing them by, e.g., creating appropriate programmes, including by modernising approaches for prevention of terrorist and lone actor attacks. Means for raising awareness (possibly training) of the relevant staff (school staff, employees in public administration, etc., in function of the building under consideration) regarding existing risks and for keeping them up to date on security matters should be tackled and designed to be inclusive and effective for diverse groups. Ways of improving cooperation between the relevant staff and Police Authorities in this context should be analysed too. Proposed solutions should be affordable to public schools and other structures accessible to the public that are usually more limited in funding. Proposals are invited from consortia involving Police Authorities and other relevant security practitioners, Civil Society Organisations, Non-Governmental Organisations, and the appropriate balance of IT specialists, psychologists, sociologists, etc. To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project. Activities proposed within this topic should address the issue from various angles, combining both social research with technological development and applications in a logical manner.

Therefore, this topic requires the effective contribution of SSH disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

Proposals should outline the plans to develop possible future uptake and upscaling at national and EU level for possible next steps once the project is finalised. Proposals should also consider, build on outcomes developed by EU-funded projects, such as the ones under HORIZON-CL3-2024-FCT-01-04 and HORIZON-CL2-2025-01-DEMOCRACY-05, and not duplicate previous research. If the proposals concern drug-related issues, they are expected to engage with the EU Drugs Agency during the lifetime of the project, including validating the outcomes. Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

HORIZON-CL3-2026-01-FCT-06: Prevention and mitigation of misuse of synthetic biology for bioterrorism purposes

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 4-5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 46 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes:

1.Increased understanding of European policy makers, research community, biotech companies, and relevant security practitioners of the threat of bioterrorism and of synthetic biology, including a thorough lawful analysis of what needs to be monitored in this context, what needs to be regulated and how;

2.Awareness raised within the related scientific community how research in synthetic biology can be used for malicious purposes.

Scope: The rising threat of bioterrorism is driven by recent scientific advancements, notably by growing accessibility of synthetic biology, genetic engineering, related commercial services and public databases, which in turn enhance their obtainability to non-state actors and individuals with malicious intentions. The proliferation of do-it-yourself biohacking and community laboratories, including gene editing and sequencing technology, dropping costs of equipment and increased simplicity of use may inadvertently facilitate knowledge and skills dissemination about biological threats and open new pathways for bioterrorism. Challenges in detection, particularly the lengthy incubation periods of biological agents, underscore the urgent need for improved identification technologies to allow for timely intervention and reduce potential mass casualties, considering both characterization through advanced tools by expert labs and simple deployable methods. Given that properly weaponized biological agents can be more lethal than nuclear weapons, their cross-border implications warrant focused attention. Recent incidents involving biotoxins across various European countries illustrate the feasibility of biological attacks. The increasing weaponisation of drones highlights an alarming trend that could extend to biological agents, further complicating threat landscapes. The potential economic and social consequences of biological attacks necessitate robust prevention and preparedness measures to mitigate overwhelming impacts on healthcare systems and society at large.

Proposals are expected to address, in a lawful manner, the emerging threats of bioterrorism in Europe, particularly in the context of synthetic biology. Recognising bioterrorism as a low-probability but high-impact event, consortia should review current and future risks, flag areas requiring reinforced monitoring, as well as identify missing regulatory frameworks necessary for ensuring public security and safety. Furthermore, proposals should bring together diverse consortia to enhance our understanding, prevention, preparedness, and response to bioterrorism and create a comprehensive approach to this pressing issue.

Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

Proposals funded under this topic are expected to provide ideas on how they would engage with the Europol Innovation Lab during the lifetime of the project. Similarly, if the proposals concern drug-related issues, they are expected to engage with the EU Drugs Agency during the lifetime of the project, including validating the outcomes.

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

HORIZON-CL3-2027-01-FCT-01: Online harms detection and investigation tools using a short development cycle model

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 7.833 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 7.83 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility conditions apply:

This topic requires the active involvement, as beneficiaries, of at least 3 Police Authorities 47 from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 48 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes:

1.Police Authorities in Europe benefit from a rapid deployment of targeted detection and investigation tools and related training materials, specifically tailored to counter current, foreseeable and emerging online harms at the outset of each development cycle;

2.Police Authorities in Europe are provided with a flexible framework for adaptation via creation of a modular toolset that allows for the incorporation of new functionalities and updates based on the latest trends and threats in online harms;

3.Enhanced European stakeholder collaboration through facilitation of partnerships among researchers, policymakers, and Police Authorities in Europe to ensure that tools are not only effective but also user-friendly, legally and ethically sound.

Scope: As the digital landscape continues to evolve, so too do the myriads of online harms that threaten citizens’ security and well-being. To address these challenges, we invite proposals for the development of detection and investigation tools that employ short development cycle models. This approach emphasizes agility and responsiveness, ensuring that tools can quickly adapt to emerging online threats, such as identity theft, disinformation, deepfakes, spoofing, phishing, digital violence, or, e.g., tools for an early detection as well as real-time monitoring and risk assessment that can identify potential fraudulent sales (“online payment fraud”) before they occur.

This topic welcomes innovative ideas focused on creating efficient detection and investigation tools to combat varying forms of online harms, which should be selected at the beginning of every new development cycle, in agreement with all stakeholders involved in the consortia, especially including concrete needs of Police Authorities. The emphasis on short development cycles allows proposals to remain dynamic, responsive to the fast-paced nature of online threats, and capable of addressing both established issues and new challenges as they arise. Proposals should focus on the iterative process of tool development, integrating feedback from Police Authorities to ensure continuous improvement and relevance in combating online harms. Ultimately, the goal is to foster a proactive and effective response to safeguarding online spaces for all users, regardless of their gender identity or expression.

Proposals are expected to provide ideas on how they would engage with the Europol Innovation Lab during the lifetime of the project. Furthermore, if the proposals concern drug-related issues, they are expected to engage with the EU Drugs Agency during the lifetime of the project, including validating the outcomes. For aspects of training of Police Authorities, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding. To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project. Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination. The project should have a minimum estimated duration of 48 months.

HORIZON-CL3-2027-01-FCT-02: Community policing in diverse societies in Europe

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 6.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 3 Police Authorities 49 and at least 2 Civil Society Organisations (or Non-Governmental Organisations) from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 50 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes:

1.New tools, skills and methodologies for Police Authorities in Europe to deal efficiently with diverse communities as well as with diversity among police personnel are identified, developed and disseminated throughout Europe, leading to, among others, an increased trust to Police Authorities in general;

2.Modern and effective training curricula for Police Authorities in Europe are developed on community policing in diverse societies, including post-conflict zones, and addressing the needs of individuals from various social, ethnic and religious backgrounds, as well as marginalized groups such as migrants, LGBTIQ people, persons with disabilities, or returnees from war.

Scope: This topic addresses challenges of community policing in increasingly diverse and sometimes also fragile societies, including the integration of returnees from conflict zones, migrants, as well as marginalized communities including LGBTIQ individuals and various ethnic and religious groups.

Encompassing a post-conflict dimension too, particularly in the context of Ukraine, this topic aims to foster inclusive community policing practices that can adapt to the complexities of diverse societal dynamics. Proposals should explore innovative and inclusive approaches in police education, training and management that go beyond traditional models, resulting in an effective engagement with a diversifying society. Proposals should also seek to identify and develop effective practices and training programs that encourage a deeper understanding of diversity among police personnel and integrate a gender-sensitive and intersectional approach when relevant. In addition, proposals should assess how effective cooperation with Civil Society Organizations (or Non-Governmental Organisations) - representing various communities - can enhance reporting mechanisms, reduce hate crimes, and strengthen trust and cooperation between the police and the population. By improving police-citizen relations across diverse European contexts, the proposals should aim to contribute to enhanced security and social stability in Europe. Proposals’ findings should generate valuable insights applicable to varied policing environments, ultimately informing police forces across Europe about non-violent conflict resolution and constructive engagement strategies. Through collaborative research and training, proposals should equip Police Authorities with the tools, skills and methodologies necessary to effectively serve and engage with diverse communities, foster social cohesion, and build trust throughout Europe.

Activities proposed within this topic should address the issue from various angles, combining social sciences with technological development and applications in a logical manner.

Therefore, this topic requires the effective contribution of SSH disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities.

Proposals should outline the plans to develop possible future uptake and upscaling at national and EU level for possible next steps once the project is finalised. Proposals should also consider, build on if appropriate and not duplicate previous research. Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. Furthermore, if the proposals concern drug-related issues, they are expected to engage with the EU Drugs Agency during the lifetime of the project, including validating the outcomes. For aspects of training of Police Authorities, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding. To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project. Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

HORIZON-CL3-2027-01-FCT-03: Open topic on enhanced prevention, detection and deterrence of societal issues related to various forms of crime

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 6.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Police Authorities 51 and at least 2 Civil Society Organisations (or Non-Governmental Organisations) from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 52 .

Beneficiaries must provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 60 000 to support effective collaboration and/or coordination with additional relevant national Police Authorities and/or CSOs/NGOs from EU Member States or Associated Countries.

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Improved, modern, uniform and validated tools, skills or methodologies as well as innovative training curricula are available for security practitioners (Police Authorities in Europe, Non-Governmental Organisations, Civil Society Organisations) to prevent, detect and deter criminal or terrorist offences under consideration, taking into account all applicable legislation and fundamental rights;

2.Enhanced understanding of the cultural and societal aspects of crime or terrorism/radicalisation offences under consideration as well as on the key challenges related to combating them;

3.Evidence-based support is available to policymakers on shaping and tuning of regulation related to crime or terrorism/radicalisation offences under consideration;

4.Enhanced perception by citizens that Europe is an area of freedom, justice, security and respect of privacy and human rights, thanks to, e.g., innovative awareness-raising campaigns explaining to citizens the key and evolving mechanisms of crime or terrorism/radicalisation offences under consideration, and how to protect against them.

Scope: Under the Open Topic, proposals are welcome to address both existing and upcoming challenges in fighting crimes that are deeply rooted in cultural and/or societal factors that are not covered by the other topics of Horizon Europe Calls Fighting Crime and Terrorism 2021- 2022, Fighting Crime and Terrorism 2023-2024 and Fighting Crime and Terrorism 2025 and Fighting Crime and Terrorism 2026-2027.

Adapted to the nature, scope and type of proposed activities, proposals should convincingly explain how they will plan and/or carry out demonstration, testing or validation of developed tools and solutions. Proposals should also delineate the plans to develop possible future uptake and upscaling at national and EU level for possible next steps after the research project completion. If applicable, research proposals should consider building on or complementing previous research, including but not limited to, research stemming from Horizon Framework Programmes, such as those funded under HORIZON-CL2 calls.

The proposals funded under this topic that concern issues which are within the mandate of Europol 53 are expected to engage with the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community. Similarly, if the proposals concern drug-related issues, they are expected to engage with the EU Drugs Agency during the lifetime of the project, including validating the outcomes. For aspects of training of Police Authorities, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding. If the funded proposal concerns radicalisation, the consortium is encouraged to liaise with the EU Knowledge Hub on prevention of radicalisation with the aim of facilitating the streamlining of their priorities and the dissemination of their results.

In this topic the integration of the gender and intersectional dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

Proposals should plan their activities opting for the Financial Support to Third Parties in order to provide financial support to practitioners (Police Authorities and/or Non-Governmental Organisations/Civil Society Organisations) for expanding the proposed work in terms of additional user groups, complementary assessments, technology- or methodology-testing activities. From 5% up to 20% of the EU funding requested by the proposal may be allocated to the purpose of financial support to third parties. Proposals must clearly describe the objectives and the expected results to be obtained, including the elements listed in the application template. Proposals are also expected to describe the methods and processes relevant to comply with the general eligibility conditions for financial support to third parties set out in General Annex B and to demonstrate effectiveness (impact).

To ensure the active involvement of and timely feedback from relevant security practitioners, i.e., Police Authorities and Non-Governmental Organisations / Civil Society Organisations, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project. Activities proposed within this topic should address, in a balanced way, both technological and societal dimensions of the issue under consideration. This topic requires the effective contribution of SSH disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related innovation activities.

HORIZON-CL3-2027-01-FCT-04: Open topic on increasing security of citizens against terrorism, including in public spaces

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 9.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility conditions apply:

This topic requires the active involvement, as beneficiaries, of at least 3 Police Authorities 54 from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 55 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Enhanced ability of Police Authorities in Europe and other relevant security practitioners to identify and prevent emergent challenges in the terrorism-related issue under consideration;

2.Harmonised and modern tools as well as procedures are available for Police Authorities in Europe and other relevant security practitioners to counter the terrorism-related problem under consideration, in full compliance with applicable legislation on protection of personal data and protection of fundamental rights;

3.Improved cooperation between Police Authorities in Europe and other relevant security practitioners, as well as with international actors, in tackling the problem in question;

4.Training curricula are available for Police Authorities in Europe and other relevant security practitioners for an improved countering of the terrorism-related problem under consideration.

Scope: Under the Open Topic, proposals are welcome to address new, upcoming or unforeseen challenges and/or creative or disruptive solutions for increasing security of European citizens against terrorism, including in public spaces, that are not covered by the other topics of Horizon Europe Calls Fighting Crime and Terrorism 2021-2022, Fighting Crime and Terrorism 2023-2024, Fighting Crime and Terrorism 2025 and Fighting Crime and Terrorism 2026-2027.

Adapted to the nature, scope and type of proposed projects, proposals should convincingly explain how they will plan and/or carry out demonstration, testing or validation of developed tools and solutions. In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

Proposals should also delineate the plans to develop possible future uptake and upscaling at national and EU level for possible next steps after the research project. Research proposals should consider, build on if appropriate and not duplicate previous research, including but not limited to research by other Framework Programmes’ projects. Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. The proposals funded under this topic that concern issues which are within the mandate of Europol 56 are expected to engage with the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community. For aspects of training of Police Authorities, cooperation of successful proposals with CEPOL is expected, provided that the Agency opts out from applying for funding. To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project. Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

HORIZON-CL3-2027-01-FCT-05: Effective and evidence-based responses to the increased availability and use of synthetic drugs and stimulants in Europe

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 3 Police Authorities 57 and at least 2 Civil Society Organisations (or Non-Governmental Organisations) from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 58 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes:

1.Evidence base is improved for effective prevention, treatment and harm reduction of synthetic drugs and stimulants in Europe;

2.Relevant European security practitioners, notably Police Authorities, Civil Society Organisations and Non-Governmental Organisations, are equipped with skills, tools and technology aimed at reducing the violence and offences associated with use and marketing of these substances, as well as at combatting drug trafficking from its origin to destination (i.e., through the entire supply chain);

3.Increased understanding of relevant European security practitioners and policymakers regarding the influence of external drivers of change of societal, technological, legal, economic and ethical nature to the availability and use of different types of synthetic drugs and drug markets.

Scope: This topic asks for proposals that seek to develop effective and evidence-based responses to the growing prevalence of synthetic drugs and stimulants, such as cocaine and crack cocaine, within the EU. As these substances increasingly influence the drug landscape, the urgent need for enhanced understanding and strategies in their prevention, treatment, and harm reduction has never been clearer. Amongst other, there is also a lack of pharmacological data for the emerging drugs, needed to do proper risk assessments and interventions of these drugs in Europe. Key focus areas include:

1.Evidence-based approaches, strengthening the evidence base to inform effective prevention strategies, treatment modalities, and harm reduction practices targeted at synthetic drugs and stimulants. This includes identifying best practices in current interventions and evaluating their efficacy.

2.Reducing violence and offending exploring strategies to mitigate the violence and criminal behaviour associated with the use and marketing of synthetic drugs. This involves understanding the socio-economic and cultural factors, including the gender, age, or other social factors, that contribute to these phenomena and proposing targeted interventions.

3.Improving technologies and tools to combat drug trafficking from its origin to destination (i.e., through the entire supply chain).

4.External drivers of change, analysing the impact of geopolitical situations, legal frameworks, and societal factors on the availability and consumption of various drugs, and addressing how international crises affect organised crime and drug markets in the EU. This includes investigating the repercussions of global developments on local drug dynamics and identifying adaptive response strategies.

In light of the underdeveloped evidence base surrounding synthetic drugs, proposals should aim to foster collaboration among researchers, policymakers, and security practitioners to create a comprehensive and effective response to this pressing issue in Europe, previous research, including but not limited to research by other Framework Programmes’ projects. Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project.

Activities proposed within this topic should address, in a balanced way, both technological and societal dimensions of the issue under consideration. The proposals funded under this topic are expected to engage with the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community. Similarly, the proposals funded under this topic are expected to engage with the EU Drugs Agency during the lifetime of the project, including validating the outcomes. Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

Destination - Effective management of EU external borders

Proposals submitted under this Destination should contribute to the expected impact of the Horizon Europe strategic plan 2025-2027: “facilitating legitimate movement of passengers and goods into the EU, while preventing illicit acts”.

This Destination will support the implementation of the European Commission Political Guidelines 2024-2029, with research and innovation for future border management contributing to resilience and competitiveness. This includes investing in the update and development of future European digital and integrated border management that respects and promotes EU values. This will contribute to equip European border, coast guards and customs authorities with the future European state-of-the-art solutions, as well as to the preparedness and capabilities to manage future challenges across the EU external borders, including potential instrumentalisation of migration, hybrid attacks, migrant smuggling, and trafficking linked to transnational terrorism and/or organised crime.

Research and innovation under this Destination will focus on preserving and securing the basic right to feel secure and on protecting and promoting fundamental rights as a priority for both European citizens and third country nationals. It will do so by funding projects which will study, develop and test possible future solutions that both strengthen, and make safer, European borders.

Projects funded under this Destination will promote technological and social research and innovation and further explore and develop solutions that enhance the technological sovereignty of European authorities, in the areas of border management, customs and supply chain security, and civilian aviation and maritime security.

To this end, proposals should contribute to the achievement of one or more of the following impacts:

1.explore and develop future capabilities for European users in the areas of border management, customs and supply chain security, and civilian maritime security, in particular in the capability areas of:

1.border surveillance;

2.facilitating travel and legitimate trade;

3.assessing and managing risk;

4.strengthening the Schengen area without introducing internal border controls;

5.maritime, aviation, land transport, cargo and customs security;

6.supply chain resilience;

7.detecting and identifying threats;

8.interoperability and cybersecurity of EU information systems and equipment;

9.safeguarding and promoting fundamental rights in the context of border management.

Research and innovation funded under this Destination will contribute to policy objectives such as:

1.the Multiannual Strategic Policy for European Integrated Border Management 59 ;

2.the implementation of the Capability Roadmap of the European Border and Coast Guard 60 and its updates;

3.the proposals to strengthen EU legislation to prevent and fight against migrant smuggling 61 ;

4.the proposals on digitalisation of travel documents and facilitation of travel 62 ;

5.the new European Internal Security Strategy 63 ;

6.the new Counter-Terrorism Agenda;

7.the European Preparedness Union Strategy 64 ;

8.the EU Port Strategy;

9.the civil security aspects of the updated EU Maritime Security Strategy 65 and of the European Ocean Pact;

10.the Copernicus service for Security 66 improving crisis prevention, preparedness and response in four key areas: Border surveillance; Maritime surveillance; Support to EU External and Security Actions, R&D for Earth Observation Security;

11.the EU Cable Security Action Plan 67 ;

12.the new European action plans against drug trafficking and against weapons trafficking;

13.the proposals for EU Customs reform 68 , including the proposed EU Customs Authority and Data Hub;

14.the security aspects of the Comprehensive EU toolbox for safe and sustainable e-commerce 69 ;

15.the security aspects of the Competitiveness Compass for the EU 70 .

Research and innovation will contribute to sustain and improve capabilities to cope with potential future critical situations or emerging challenges regarding both the flow of people and the flow of goods across external EU borders. These capabilities may include but not limit to:

1.monitoring, preparedness and reaction in border management tasks, managing irregular or illegal activities involving people or goods across external borders of the EU;

2.safeguarding and promoting fundamental rights and EU values, and ensuring legal compliance, in efficient border management;

3.efficiency, performance, environmental impact and reaction in border management tasks in all geographical and meteorological conditions;

4.integrated and continuous border surveillance, situational awareness and analysis support;

5.safety, user experience and performance of practitioners’ staff in border management;

6.security, privacy and usability of identity and (travel) documents and credentials;

7.facilitating travel of bona fide passengers across external borders of the EU;

8.prevention, detection and disruption of trafficking of dangerous, illicit and illegal goods and materials through external borders of the EU and the supply chain.

Furthermore, research and innovation under this Destination will contribute to:

1.safeguard the technological sovereignty of the EU in critical security areas by contributing to a more competitive and resilient EU security technology and industrial base;

2.lower the environmental impact and footprint of border, customs and supply chain security tasks, through innovative solutions and methods;

3.integrate and improve safety and cybersecurity of EU information systems, of innovative equipment, and of information and data in these areas, especially during their exchange at operational or tactical levels;

4.improve interoperability both among proposed solutions and also with future technological developments in the areas of border management, customs and supply chain security, and civilian maritime and aviation security.

Research projects funded under this Destination should engage with all stakeholders involved, including travellers, migrants, and operators, as relevant.

Projects should align and contribute primarily to the realisation of the Capability Roadmap of the European Border and Coast Guard (EBCG) published by the EBCG Agency (Frontex), especially the Roadmap’s mid- and long-term perspectives. The Roadmap provides strategic vision for investments into the development of capabilities and is the result of integrated planning between the Member States and the European Border and Coast Guard Agency. Proposals submitted under this Destination should explain the alignment primarily with the Capability Roadmap and the plans for further uptake of the research outcomes, especially by involved practitioners in line with their national Capability Development Plans.

Frontex will be closely associated with and will assist Member States and the European Commission in drawing up and implementing relevant research and innovation activities. The European Union Agency for the Operational Management of Large-Scale IT Systems in the Area of Freedom, Security and Justice (eu-LISA) may also assist the European Commission on relevant research and innovation activities and specific topics.

At the proposal preparation stage, Frontex and/or eu-LISA will not provide guidance on or otherwise be involved in the preparation of project proposals. However, proposals should consider and anticipate that Frontex and/or eu-LISA may observe pilots and demonstrations during project implementation to facilitate the future uptake of innovations within the border and coast guard community.

To accomplish the objectives of this Destination, additional eligibility conditions have been defined regarding the active involvement of relevant security practitioners or end-users in the research projects’ consortia.

Cross-community and cross-authority synergies within civil security can be an asset, for example in relation to combat crime and terrorism (across external borders); Disaster-Resilient Society (regarding natural hazards and disasters); Resilient Infrastructure (regarding threats to infrastructures, coming from across borders).

Proposals submitted under this Destination should demonstrate how they plan to build on relevant predecessor projects; to consider the citizens’ and societal perspectives; to include education, training and awareness raising for practitioners and citizens; to measure the achieved TRL.

Proposals should delineate the plans for further development to subsequent TRLs as well as uptake (industrialisation, commercialisation, acquisition and/or deployment) at national and EU level, should the research deliver on its goals. Knowledge and technologies developed by research funded under this Destination may be taken up or tested operationally with co-funding of instruments such as the Integrated Border Management Fund, in its components of the Border Management and Visa Instrument (BMVI) and Customs Control Equipment Instrument (CCEI), and/or subsequent funding instruments. Member States authorities participating in research projects are encouraged to use those instruments for uptake (piloting, testing, validation, scale-up, transfer, acquire, deploy, etc.) of innovative solutions developed from research, as early as TRL 7.

Research projects should consider, build on (if appropriate) and not duplicate previous research, including but not limited to research by other Framework Programmes projects.

Successful proposals under this Destination are invited to cooperate with other EU-led or EU-funded initiatives in the relevant domains, such as the Knowledge Networks for Security Research & Innovation funded under Horizon Europe Cluster 3, or other security research and innovation working groups set-up by the Commission or EU Agencies.

Funded projects are encouraged to liaise with the European Commission’s Joint Research Centre (JRC), for example with regards to a possibility of testing the relevant research outputs at the JRC Border Security Lab.

Where possible and relevant, synergy-building and clustering initiatives with projects in the same area should be considered, in coordination with the Community for European Research and Innovation (CERIS) 71 .

Cluster 3 will further incentivise the use of European Space Programmes’ services for border management innovation where relevant and their services and capabilities, including demonstration and validation of new technologies in operational environments.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Proposals are invited against the following topic(s):

HORIZON-CL3-2026-01-BM-01: Advanced border surveillance and situational awareness

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 6.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Border or Coast Guard Authorities from at least 2 different EU Member States or Associated countries. For these participants, applicants must fill in the table “Eligibility information about practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 72 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Improved detection, localization, characterization and, when applicable, neutralisation, of unmanned vehicles alone or in swarms, involved in trafficking or smuggling activities across external borders, while complying with legal and ethical guidelines;

2.Improved border situational awareness, especially in the context of large-scale movements of people across borders, including from potential instrumentalisation of irregular migration, conflicts, social, economic, environmental and climate stress;

3.Better safeguard and promotion of fundamental rights thanks to enhanced situational awareness;

4.Reliable, redundant detection and reaction capacities without putting staff and society at risk.

Scope: Capabilities for situational awareness and surveillance of land and sea borders need improvement, in consideration of potential future challenges that may require updated capabilities. These challenges may include potential future large-scale movements of people across external borders, resulting from future attempts to instrumentalisation of irregular migration, but also from conflicts, social, economic, environmental and climate stress in the European neighbourhood; as well as increasing availability and capability of unmanned aerial, surface, and underwater vehicles with increased payload capacity and range that make it easier to transport goods and, possibly, persons, including in connection will illicit or illegal activities such as trafficking of goods and smuggling of people across external EU borders. These challenges will be particularly relevant in regions close to the European neighbourhood.

This may be particularly relevant for unsupervised and difficult-to-control land and sea borders of the Union and the Schengen area.

Research funded under this topic should develop solutions that, through better awareness, improve efficiency and reaction time of detection, search, rescue, and recovery operations near land and sea borders, in diverse geographical and meteorological conditions, taking into account the different and diverse needs. Research funded under this topic can also promote cross-border cooperation at European regional level around innovative border management solutions demonstration testbeds.

Actions funded under this topic should develop solutions that go beyond state-of-the-art in clearly demonstrable ways, including measurable improvements in detection range, accuracy, response time, automation, and system resilience.

Improved border surveillance and situational awareness must better safeguard and promote fundamental rights and EU values, with a particular regard to human rights, using an inclusive approach that addresses diverse needs. Solutions should also provide reliable and redundant capacities, while ensuring the safety of staff, users, and persons who may be victim of illicit activities across external borders.

The EBCG Capability Roadmap recognises that future capabilities that help detect cross-border irregularities and cases requiring Search and Rescue activities are essential. Solutions should be modular and scalable to cater to the regional and challenges specificities.

Compatibility and integration with the European Border Surveillance System (EUROSUR) is essential, and compatibility and/or exploitation of other European information-sharing environments, like the Common Information Sharing Environment (CISE), would be an additional asset.

Proposals should demonstrate that the proposed equipment and technologies contribute to cost reduction and energy efficiency of border surveillance and situational awareness operations.

Proposals submitted under this topic are expected to address the priorities of the European Border and Coast Guard (ECBG) and of its Agency (Frontex). This should start from the definition of requirements and the design phase, including alignment with the EBCG Capability Roadmap and on the engagement with the Agency during the project implementation. At the proposal preparation stage, Frontex will not provide guidance on or otherwise be involved in the preparation of project proposals. However, proposals should consider and anticipate that Frontex may observe pilots and demonstrations during project implementation to facilitate the future uptake of innovations within the border and coast guard community.

To ensure active involvement and timely feedback from relevant security practitioners, proposals should include a mid-term deliverable consisting of an assessment of the project’s mid-term outcomes, conducted by the practitioners involved in the project.

HORIZON-CL3-2026-01-BM-02: Accessible and available travel facilitation

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Border or Coast Guard Authorities from at least 2 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 73 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Improved trusted, secure, and easier automated seamless facilitation for travel, border crossing through border crossing points (BCPs), and/or visa procedures with an integrated approach, minimized risk for bias, and accessible for all travellers minimising digital divides;

2.Facilitated solutions with same approach adaptable by all European border control staff, in all conditions and border control points (BCPs);

3.Reduced workload and improved safety, user experience and performance of practitioners’ staff involved in border management.

Scope: Facilitation of travel and border crossings at border crossing points (BCPs) across the external EU borders went, and is further going, through developments thanks to updated procedures and regulatory frameworks and to innovative European technologies. From automated border control (ABC) gates to “no-gate” solutions and “seamless travel”, and with systems like the Entry-Exit System (EES), the Electronic Travel and Information Authorisation System (ETIAS), and the development of digital travel credentials and digital identity more in general, Europe has one of the most advanced, secure and facilitated border check systems in the world.

Travel facilitation schemes are still not as fair, inclusive and accessible as they should be. There are several technical exceptions that for example make difficult for families, other groups of people travelling together, people with disabilities and/or reduced mobility, or with relatively lower digital skills, to smoothly use travel and border crossing facilitation solutions. This is a capability gap of travel facilitation systems that has an impact on both a fair accessibility and availability for travellers, and on performance and efficiency of the systems themselves. Travel facilitation systems should ensure both security and easy passenger flow, while remaining accessible to all travellers.

On the other hand, both technical systems and procedures may have differences depending on the context or the BCP of application. This may be a limit for the performance and user experience of European integrated border management, especially in a perspective of a larger help to national members of the European Border and Coast Guard (EBCG) from the Standing Corps of the European Border and Coast Guard Agency (EBCGA).

According to the EBCG Capability Roadmap, legal border crossings should be as swift and simple as possible, while at the same time allowing a smooth crossing of bona fide persons, and of the goods carried with them.

Innovation actions funded under this topic will develop and test solutions for advanced seamless travel and border crossing and/or visa procedures, protecting and promoting fundamental rights, minimising the risk for bias and being accessible for all travellers, with no or minimised limitations depending on age, sex, gender, disability, physical or digital abilities. To minimise potential for discrimination or physical or digital divide regarding travel facilitation schemes, solutions should be inclusive and accessible.

Furthermore, solutions should be tested for use with the same approach by all European border control staff in all conditions and BCPs.

The proposed solutions can include innovative technologies, innovative processes, innovative knowledge and/or a combination thereof. Solutions should include automated decision support systems suggesting to the end-users (border checks operators) which procedure, technology or database can be used without infringing rights of travellers. Solutions should also integrate and, if appropriate, further develop, biometric matching that minimises data shared (for example limiting to matching scores) to improve data protection.

Proposals submitted under this topic are expected to address the priorities of the European Border and Coast Guard and of its Agency (Frontex) and of the European Union Agency for the Operational Management of Large-Scale IT Systems in the Area of Freedom, Security and Justice (eu-LISA). This should start from the definition of requirements and the design phase of their work, including basing on the EBCG Capability Roadmap; and on the engagement with the Agencies during the implementation of the project. At the stage of proposal preparation, Frontex and eu-LISA will not provide any guidance on, or otherwise be involved in the preparation of, project proposals. Proposals should consider and foresee that Frontex and eu-LISA may observe pilots and demonstrations when the project will be implemented, with the aim of facilitating future uptake of innovations for the border, customs and coast guard community.

To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project.

Depending on the particular scope of the proposal, participation of Customs Authorities is welcome.

HORIZON-CL3-2026-01-BM-03: Reliability of age assessment methods in the context of security and border management

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.33 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 1.33 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Border or Coast Guard Authorities from at least 2 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 74 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Improved protection of minors, including by more reliable age assessments and by minimising the use of intrusive age assessment methods;

2.Improved adaptation, preparedness and cooperation of authorities in the fight against human trafficking;

3.Expanded European-based knowledge on reliability, accuracy and effectiveness of age assessment methods.

Scope: Many unaccompanied children and young persons arriving at the external EU borders and seeking asylum, lack official documents showing their identity and age. Age assessment methods are important as they contribute to the determination of, for example, where an individual will be initially housed and what services, supports, and legal processes they will receive to ensure protection and, if applicable, child protection.

In other cases, minors are victim of trafficking of human beings (THB) criminal activities, either across the EU external borders, or within the EU borders. In other cases again, age assessment methods are necessary for law enforcement investigations on protecting children, forensic investigation, and/or the identification of victims.

No age assessment method can offer a 100% reliability. Different approaches have different sensitivity and specificity, and different sample sizes and representativeness, and some approaches are based on a non-European knowledge base. Furthermore, there is considerable variation in methods of age assessment. Methods may use approaches as diverse as interviews, psychological assessments and other holistic approaches; medical approaches such as X-rays, CT scans, DNA methylation, dental observation, or other analyses; other approaches such as image analysis; and they may use or not artificial intelligence (AI) for data analysis.

EU regulations, and guidelines by the European Union Asylum Agency (EUAA) 75 , include safeguards and recommendations, such as that the least invasive methods should be used, and that medical methods should be used as a last resort. Further studies, reports or documents have also been elaborated by the European Migration Network 76 , European networks of security practitioners for innovation, as well as at national level. The action funded by this topic should also consider these, as well as previous research, including but not limited to research by other relevant EU Framework Programmes projects.

This Coordination and Support Action should not develop methods or technologies of age assessment. Rather, it will analyse, including with practitioners, the current and potential methods for age assessment. It should assess and compare scientific reliability, sensitivity and specificity of different methods, as well as their potential risks for fundamental rights and how to minimize them.

While the research results would not imply any legislative or policy decision on age assessment methods, the research will develop evidence-based results on options for more (compared to the state-of-the-art) appropriate models of age assessment methods that protect fundamental rights, ensuring the use of an inclusive approach that addresses diverse needs. The results of research funded by this topic will contribute to capabilities for better identification of children and minors in the migratory, security, border management and other contexts, following the principles of the EU Strategy on the rights of the child 77 . They will also contribute to the exchange of practices among European authorities.

Synergies with other Horizon Europe Cluster 3 Destinations, such as “Better protect the EU and its citizens against Crime and Terrorism” and “Disaster-Resilient Society for Europe”, as well as with Destinations of Horizon Europe Cluster 2 “Inclusive Society”.

HORIZON-CL3-2027-01-BM-01: Open topic on research and innovation for effective management of EU external borders that promotes fundamental rights and EU values

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Border, Coast Guard or Customs Authorities from at least 2 different EU Member States or Associated countries. For these participants, applicants must fill in the table “Eligibility information about practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 4-5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 78 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to the following expected outcome:

1.Improved border management solutions that protect and promote fundamental rights of both EU citizens and Third Country Nationals.

Scope: Under this Open topic, proposals are welcome to address new, upcoming or unforeseen challenges and/or creative or disruptive solutions that are not covered by the other topics of this Destination in 2026 and 2027.

In particular, this topic will fund research projects that explore, develop and test knowledge and technology solutions in the areas of border surveillance, border checks, customs and supply chain security, and civilian maritime and aviation security border management that protect and promote fundamental rights of both EU citizens and Third Country Nationals, and EU values.

Adapted to the nature, scope, type and target TRL of proposed projects, proposals should convincingly explain how they will plan and/or carry out demonstration, testing and validation of developed tools and solutions. Proposals should be convincing in explaining the methods they intend to use for demonstrating, testing and validating the proposed tools and solutions ensuring that the intersectional perspectives of diverse groups, including gender, sex, age, disabilities, race or ethnicity, sexual orientation and migrant status are integrated and considered. Proposals should also delineate the plans to develop possible future follow-up research and development and/or uptake, upscaling and/or application and use at national and EU level as possible next steps after the research project.

Research proposals should consider, build on if appropriate and not duplicate previous research, including but is not limited to research by other Framework Programmes’ projects.

HORIZON-CL3-2027-01-BM-02: Trusted, secure, quality future digital travel credentials

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Border or Coast Guard Authorities from at least 2 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 4-5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 79 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Development, testing and integration of issuance, validation and sharing capabilities for possible future types (beyond Type 1) of Digital Travel Credentials (DTC);

2.Integration of innovative, on-the-move, biometrics and remote biometric acquisition modalities to support the use of DTCs;

3.Improved secure connectivity and interoperability for future DTCs;

4.Improved capability of issuance of emergency travel documents and/or emergency DTCs.

Scope: Issuance, verification and management of digital travel credentials (DTCs) is relevant for border management, immigration and visa management. Furthermore, it could also be relevant to combat illicit activities such as terrorism, crime or frauds. This topic aims at supporting research and innovation that explore, develop and test enhanced capabilities for securely issuing, verify and manage (including sharing) possible future types of digital travel credentials (DTCs) for travel across the external borders of the EU.

The proposed solutions must be compatible with current, planned or foreseeable EU DTCs formats, and with applicable International Civil Aviation Organisation (ICAO) schemes, but they should also push forward to possible further types of DTCs (“Type 2” and “Type 3”).

Additionally, the funded actions should also work on the integration of current and new biometrics, and/or new biometric acquisition modality, in support of DTCs. This includes but does not limit to biometrics such as fingermark, palmprint, palmmark, rolled fingerprint, contactless fingerphotos, and biometric acquisition modalities such as remote and on-the-move, including those modalities developed by previous projects funded by this Destination of Horizon Europe Cluster 3. The project should develop and/or contribute to reference biometric sample quality assessments standards for these biometric modalities included in the DTCs, compatibly with existing relevant tools such as the Open Source Face Image Quality (OFIQ), or improving forward-looking interoperability, for example between contact and contactless fingerprint data.

The funded research project(s) can also address the use case of verification, issuance or re-issuance of (emergency) DTCs in cases of emergencies (including evacuations of EU citizens).

Funded research can additionally address the security of breeder documents, which risk to be “weak links” when they are used to obtain genuine, secure travel credentials.

Proposals submitted under this topic are expected to address the priorities of the European Border and Coast Guard and of its Agency (Frontex) and of the European Union Agency for the Operational Management of Large-Scale IT Systems in the Area of Freedom, Security and Justice (eu-LISA). This should start from the definition of requirements and the design phase of their work, including basing on the EBCG Capability Roadmap; and on the engagement with the Agencies during the implementation of the project. At the stage of proposal preparation, Frontex and eu-LISA will not provide any guidance on, or otherwise be involved in the preparation of, project proposals. Proposals should consider and foresee that Frontex and eu-LISA may observe pilots and demonstrations when the project will be implemented, with the aim of facilitating future uptake of innovations for the border and coast guard community.

To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project.

HORIZON-CL3-2027-01-BM-03: Detection and characterisation of threats or illegal/ smuggled goods in cargo

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 14.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Customs Authorities from at least 2 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 4-5 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio, grants will be awarded to applications not only in order of ranking but at least also to one proposal that is the highest ranked within each of the two options: Option a, and Option b; provided that the applications attain all thresholds

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 80 .

Beneficiaries must provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 100 000 to support the expected outcomes of the topic and effective collaboration and/or coordination with additional relevant national Customs Authorities, including testing and validation activities within the projects; the organisation of testing and validation activities also justifies the maximum amount to be granted to each third party indicated above.

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Increased security of air, maritime, land, or postal transport, cargo and supply chain;

2.Address accidental or intentional explosions, fires, noxious chemicals, material degradation, or autonomous threats in cargo;

3.Enhanced capabilities to detect, characterise, track and trace, and seize dangerous, regulated, illicit devices, goods, or material;

4.Increased mobility of the customs authorities’ resources and equipment and improved agility for a faster and more coordinated response;

5.Interoperability of customs control equipment and interconnectivity with other systems, including integration of logistical operations, and/or increased inter-agency and cross border collaboration.

Scope: Today’s global economy and high-volume trade flows require much and fast transport to deliver products worldwide. Traders and consumers expect quick and easy transactions, while customs administrations face the challenge of controlling the goods without disrupting their flow. This is exploited by organised crime and terrorist organisations, which take advantage of the large amount of goods to conceal threats or illegal and/or dangerous materials in legal commercial cargo, with the aim of causing damage, disruption, or of it illegally crossing borders unnoticed.

Customs authorities must ensure a high level of compliance with both security and revenue objectives: trafficked materials may represent a threat, and undetected smuggled licit materials entering the EU deprive the Member States of the revenue due if the material had been legally traded. In addition, illegal trafficking can have an impact in the environment (such as biodiversity loss or deforestation) or for the EU citizens’ safety and health.

The air and maritime cargo contexts present security challenges as well as high potential consequences of threats, primarily but not limited to explosives and incendiary devices. Air cargo can represent continuity assurances to cope, at least in the short term and for critical lines, with supply chain and/or distribution crises; while maritime cargo remains the most common transport mode in global trade. The risk for well-concealed materials not being detected during screening, or the risk of concealment during the supply chain is pressing.

Logistical hubs also need to strengthen their capabilities to adapt to sudden changes, and customs authorities need to mobilise their available resources to ensure efficient and fast controls. The need for better mobility and improved agility for customs is accompanied by the need to deploy scalable solutions, that are interoperable with other systems to facilitate co-sharing of equipment between BCPs and between Member States.

Innovation actions funded under this topic should develop and test solutions for cargo security, relevant to one or more transport modes (maritime, air, postal, road, or rail); and usable at one (or more) crucial point(s) of the supply chain. Innovation can also develop enhanced capabilities for customs to detect illicit, regulated and / or dangerous goods and transactions, and to be able to effectively characterise them in a timely manner. Improved tracking and tracing capabilities will facilitate the seizing of the materials while contributing to collecting data and evidence to further support investigations and prosecutions.

Proposals are expected to address one of the following options that should be explicitly selected:

Option a: security of cargo

Option b: detection of smuggled and trafficked goods/materials in cargo

Detection capabilities should target one or more type(s) of dangerous, illicit and/or illegal goods or materials, including: explosive or incendiary devices; illicit drugs and their precursors; illegally traded species, including covered by the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) and considering the Regulation on Deforestation-free Products 81 ; illegally traded cultural property; contraband; trafficked weapons; chemical, biological, radiological, nuclear and explosive (CBRN-E) material or precursors; F-gases; and/or various modi operandi related to cross-border trafficking, including involving cargo.

Where the identification of illegal goods cannot be achieved without opening containers (for example, in the case of species or their parts), and where imagery, chemical, or molecular tests are required, appropriate measures should be established to reduce the response time between sampling and expert assessment, thereby minimizing disruption to the flow of goods.

Examples of technologies and approaches that can be explored by the research actions include (non-prescriptive and non-exhaustive): smart active defuse systems, sensors, artificial intelligence, tracking and tracing systems, distributed ledger technologies, non-intrusive inspection, automated threat recognition systems, and screening and scanning systems.

Equipment and technologies enabling increased security of cargo should contribute to cost and energy efficiency, limit their environmental impact and being more sustainable when they will be taken up in the future. An increased security of air cargo, furthermore, should not be regarded as an incentive to use air transport when this has a higher environmental and emissions impact, but prioritised on critical supply lines and/or situations.

Proposals received under this topic should demonstrate how the project would integrate the perspective for the whole supply chain, from load to delivery. Proposed solutions should be interoperable with the different relevant equipment and systems deployed by the customs authorities. Proposals should demonstrate how their solutions would align with existing interoperability standards (if any), and consider issues of cybersecurity and EU technological sovereignty and strategic autonomy. Proposals submitted under this topic are expected to align with the customs reform (if adopted) and customs policy priorities, and the projects should, once started, align with the policy priorities of the proposed EU Customs Authority and its Data Hub (if established).

Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project.

Research projects should consider, build on (if appropriate) and not duplicate previous research, including but not limited to research by other relevant EU Framework Programmes projects on security research.

Proposals should delineate the plans for further development to subsequent TRLs as well as uptake (industrialisation, commercialisation, acquisition and/or deployment) at national and EU level, should the research deliver on its goals. The results of the research should be taken up by EU customs authorities with the support of the Customs Control Equipment Instrument (CCEI) and/or subsequent funding opportunities, or the proposed EU Customs Authority and its Data Hub (once established).

Synergies within civil security can be an asset, for example with Better protect the EU and its citizens against Crime and Terrorism and Resilient Infrastructure.

Destination - Resilient Infrastructure

Following the Commission political guidelines 2024-2029 this Destination will support the implementation of the directives on the Resilience of Critical Entities (CER) 82 and on Network and Information Security (NIS2) 83 . Actions will focus on upgrading physical and digital security and resilience of critical entities and their supply chains, including the European strategic autonomy aspect.

Research and innovation investments will continue addressing emerging and existing challenges for critical entities, including hybrid threats. Cross-destination and cross-cluster cooperation will be fostered to better understand the risks, including technological, organizational and underpinning societal issues, and to deliver innovative, scalable, interoperable, long-lasting and effective tools to anticipate, prevent, detect, monitor, manage and investigate them. These actions will contribute to realising the objectives of the ProtectEU – a European Internal Security Strategy 84 , Counter-Terrorism Agenda 85 and the European Preparedness Union Strategy 86 .

Furthermore, this Destination will continue to develop measures to improve the resilience, safety, and security of urban and peri-urban areas against deliberate or accidental human actions, preserving citizens’ right to feel safe and have access to essential services, while meeting climate resilience objectives of the EU Adaptation Strategy 87 .

Projects funded under this Destination will promote technological and social innovations enhancing the sovereignty, competitiveness and strategic autonomy of European critical entities, authorities and operators including their respective supply chains. Moreover, submitted proposals should consider current policy developments and meet expectations of the following EU legislation and policy documents, whichever would be relevant to the challenges addressed by the proposal: 

1.EU Cybersecurity Strategy 88 ;

2.EU Maritime Security Strategy 89 ;

3.EU Aviation Security Strategy 90 ;

4.Europe-wide Climate Risk assessment (EUCRA) and Commission Communication on Managing Climate Risks;

5.European Economic Security Strategy 91 ;

6.Joint Framework on Countering Hybrid Threats 92 and the Joint Communication on Increasing Resilience and Bolstering Capabilities to Address Hybrid Threats 93 ;

7.EU C-UAS Strategy 94 ;

8.EU Space Strategy for Security and Defence 95 ;

9.EU Disaster Resilience Goals 96 ;

10.European Preparedness Union Strategy 97 ;

11.EU Action Plan on Cable Security 98 ;

12.European Water Resilience Strategy 99 .

To this end, these proposals should contribute to the achievement of one or more of the following generic impacts:

1.physical and/or digital aspects of critical entities safety and security are considerably improved, while dependencies on non-European technologies, services, and resources are significantly reduced;

2.new and upgraded systems support the interoperability enabling rapid response and recovery from complex security incidents without significant human involvement, and situational awareness and information sharing functionalities are available, especially where emergency responders’ intervention is required;

3.security-by-design, preparedness-by-design and where relevant circularity-by-design are default features of both newly created and upgraded infrastructure;

4.urban, peri urban areas are more resilient through technological, organisational, and social innovations, and deepened public involvement;

5.European citizens awareness and reaction capabilities in case of critical infrastructure disruption is considerably raised.

Research projects should consider, build on (if appropriate) and not duplicate previous research, including but not limited to research by other Framework Programmes projects.

It will be important also to take into account how research results can be advanced to deployable solutions after the projects lifetime, utilising validation and capacity-building programmes like the Internal Security Fund, Digital Europe Programme and other.

Where possible and meaningful, synergy-building and clustering initiatives with successful actions in the same, or other relevant areas. should be considered, including the organisation of international events in coordination with the Community for European Research and Innovation for Security (CERIS) 100 .

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Proposals are invited against the following topic(s):

HORIZON-CL3-2026-01-INFRA-01: Tools and processes to support stress tests of critical infrastructure

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.835 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 9.67 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

The following additional eligibility conditions apply:

This topic requires involvement as beneficiaries of at least 3 relevant practitioners from EU Member States or Associated Countries. Depending on the specific proposal submitted, these practitioners should represent one or several of the following portfolios:

1.critical infrastructure operator,

2.authority responsible for critical infrastructure resilience,

3.civil protection authority,

4.law enforcement or private companies providing security for critical infrastructure.

For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 101 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following outcomes:

1.Critical infrastructure operators and authorities have access to efficient, adaptable, resilient and reliable tools and processes enabling or improving virtual and physical stress tests of their respective assets/ and operations;

2.Critical entities have broader and deeper understanding of their technical and operational vulnerabilities and adaptive capabilities, improving the scenario building and stress tests exercises;

3.Systems allowing notification and collaboration under stress conditions are available for relevant stakeholders;

4.Critical entities are better equipped for post-incident investigations, including data collection, analysis and improved learning, management and sharing in a secure manner;

5.Improved operational procedures including incidents management and training curricula are developed.

Scope: The resilience of critical entities is of paramount importance as disruptions to these systems can have significant consequences for the whole economy, public health, security or safety. These systems, responsible for providing essential services for modern society, are increasingly complex and interconnected, making them vulnerable to a range of threats, including cyber-attacks, physical attacks, malfunctions, human-induced or natural disasters.

The objective of this topic is to facilitate the stress testing of critical infrastructure by providing specialized tools and methodologies and support validation. This will enable the identification and testing of technical and operational vulnerabilities, inform of effective solutions to mitigate these risks, and facilitate the collection and analysis of data to enhance resilience plans that shall be established by each critical entity. Building on the insights gained from previous exercises, the ultimate goal is to establish more robust and comprehensive stress testing protocols, thereby ensuring the reliability and integrity of critical infrastructure.

The proposed solutions may, among others, support simulation and modelling, multi-hazard and multi-threat scenario building, data analytics, including geospatial information, Digital Twins, assessment of risks and adaptive capabilities, as well as impact of human factors.

These solutions should be designed to be inclusive and accessible, considering the needs of diverse users and stakeholders. Solutions should allow flexible configuration taking into account the evolving nature of threats and hazards. If feasible they should also be adaptable to different sectors and should support stress testing under diverse environmental and geographical conditions, including operation in harsh and remote environments. Moreover, they should comply with the relevant legislative frameworks and allow application of the developed tools under the current regime taking into account the sensitivity and confidentiality of the processed information.

Coordination among the successful proposals from this topic and projects funded under HORIZON-CL3-2025-01-INFRA-01: Open topic for improved preparedness for, response to and recovery from large-scale disruptions of critical infrastructures and HORIZON-CL3-2025-01-INFRA-02: Open topic for role of the human factor for resilience of European critical entities, should be envisaged in order to avoid duplication, share resources and exploit complementarities and opportunities for increased impact.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

Where relevant, funded projects are encouraged to liaise with the European Commission's Joint Research Centre, for complementary real-scale testing at the Reaction Wall and HopLab of the European Laboratory for Structural Assessment (ELSA).

HORIZON-CL3-2026-01-INFRA-02: Security challenges of the green transition in urban und peri urban areas

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 4.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires involvement as beneficiaries of at least 3 relevant practitioners from EU Member States or Associated Countries. Depending on the specific focus of the proposal submitted, these practitioners should represent one or several of the following portfolios:

1.critical infrastructure operator,

2.authority responsible for critical infrastructure resilience,

3.civil protection authority,

4.safety or security first responders,

For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 102 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following outcomes:

1.Identification and analysis of potential new security risks related to innovative technologies being deployed in the urban and peri-urban environments;

2.Innovative and modern tools to identify and measure changes in urban and peri-urban areas caused by the green transition, insofar as they concern security and possible resilience approaches;

3.Verification of measures countering potential safety and security risks, hazards and challenges arising in areas hosting green technologies;

4.Contribution to building awareness and societal acceptance for the safety and security aspects of the green transition;

5.Impacts of incidents involving new and emerging technologies are examined, including environmental and climate risks;

6.Security, safety and resilience aspects of the supply chains of green technologies are analysed, including the technological and resource dependencies, and their aligning with the European strategic autonomy principle;

7.Authorities and critical infrastructure operators are equipped with efficient evaluation methodologies for safe and secure deployment and integration of new and emerging technologies into urban and peri-urban areas.

Scope: Climate change and environmental degradation are an existential threat to the world, and the green transition is a critical component of the EU's strategy to reduce and mitigate their impacts, as well as to contribute to the European competitiveness. This approach is also part of the effort to transform Europe into a modern, resource-efficient, resilient and competitive economy. However, rapid deployment of new and emerging technologies, such as, but not limited to: green and grid-interactive roofs and walls, solar power installations, electric vehicle charging stations, energy storages, smart sensors and surveillance systems, green transportation systems, nature-based or other sustainable or reused construction materials, or specific infrastructure solutions may create security risks through new interdependencies including legacy infrastructure, the accumulation of deployed solutions, or otherwise create new potential risks and hazards of unknown scale and origin.

Proposals submitted under this topic should investigate the integration of sustainable & environmentally friendly technologies into urban and peri-urban areas to identify and explore physical and cyber risks and vulnerabilities resulting from this phenomenon, including, but not limited to: battery fires, toxic leaks, electric shocks, structural integrity, toxic waste, data privacy, land management disruptions, including potential negative impacts on the natural environment, or social and community tensions. The proposals should also consider the threat of malicious access, software and data manipulation and misuse of managing systems potentially leading to harm to health, loss of life, environmental damage or economic damage, regardless of whether the intention is criminal, vandalism, hybrid attack or other.

The ultimate goal of this research is to inform operators, first responders and authorities on how to mitigate risks, enhance their preparedness and improve their response to potential incidents. By recognizing emerging threats, it should be possible to prevent major incidents from occurring, and in the event of an accident, provide effective strategies, managerial advice, processes and methodologies to respond and recover. The research should provide recommendations that are tailored to diverse communities and context needs such as those with different socio-economic profiles, adapted to people of different ages and genders to identify and mitigate physical and cyber risks and vulnerabilities. Proactively addressing major safety and security risks associated with the green transition will help to future-proof these technologies, build public trust, and promote their widespread acceptance, backed by evidence-based safety and security policies.

The proposed research should provide a comprehensive understanding of adaptive capabilities, the risks and vulnerabilities associated with green technologies, as well as practical recommendations for mitigating these risks and ensuring their safe, resilient and secure deployment while utilising the nature-based solutions and respecting principles of biodiversity. By doing so, it will contribute to the development of a resilient and sustainable urban environment, where the benefits of green technologies can be fully realized while minimizing their potential risks and negative impacts.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

HORIZON-CL3-2026-01-INFRA-03: Targeted innovative capabilities for the resilience of critical entities to natural and human-induced disasters, including hybrid scenarios

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 9.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

This topic requires involvement as beneficiaries of at least 3 relevant practitioners from EU Member States or Associated Countries. Depending on the specific proposal submitted, these practitioners should represent one or several of the following portfolios:

1.critical infrastructure operator,

2.authority responsible for critical infrastructure resilience,

3.civil protection authority,

4.first responders’ organisations or agencies,

5.authority in charge of managing NaTech (Natural Hazard Triggered Technological) events,

6.law enforcement or private companies providing security for critical infrastructure.

For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 103 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following outcomes:

1.Improved understanding of systemic vulnerabilities of critical entities including physical, digital, operational, and cross-sectoral dimensions, in the face of compound natural and human-made disaster risks;

2.Verification of existing measures countering potential NaTech risks;

3.Demonstration of advanced technological solutions that enhance the ability of public and private providers of critical services to prepare for, respond to, and recover from complex, multi-hazard scenarios, including cascading or hybrid NaTech events;

4.Deployment of common platforms and operational tools for dynamic risk assessment, decision support, between public authorities, first responders, and critical infrastructure operators during disruptive events;

5.Strengthened multi-level and cross-border cooperation frameworks for integrated emergency and continuity management, ensuring seamless coordination across sectors, governance levels, and jurisdictions.

Scope: Recent compound and cascading disasters have demonstrated the urgent need to reinforce the resilience of critical entities against a wide spectrum of hazards, including both human-induced incidents, natural events such as floods, wildfires, earthquakes, and storms, and natural hazard triggered technological (NaTech) accidents, including hybrid scenarios. The vulnerability of key infrastructures is exacerbated by their growing interdependencies and the systemic propagation of risks across sectors and borders. In this context, ensuring the monitoring, protection and continuity of essential services has become fundamental to preserving and enhancing societal resilience.

This topic aims to support the development and demonstration of targeted high-tech capabilities that address specific preparedness, operational, and recovery gaps in the resilience of critical entities 104 under multi-hazard and NaTech conditions. It calls for moving beyond generic resilience frameworks toward sector-specific, interoperable, and modular technological and governance solutions that can be deployed and tested in realistic operational settings.

Proposals should be grounded in existing risk assessments and draw on lessons learned from recent disruptive events. They are expected to deliver measurable improvements in both technological and organisational resilience through the identification and prioritisation of critical capability gaps, especially where cascading and cross-sectoral risks are likely to arise. In parallel, adaptive continuity planning and decision-making tools should be designed to enhance situational awareness, support dynamic response coordination, and maintain service continuity in fast-evolving crisis scenarios. 

Proposals should also demonstrate cross-border, multi-actor coordination mechanisms through simulations or testing in real operational environments, involving public authorities, emergency responders, and critical service operators or representative environments where critical infrastructure is particularly exposed to multi-hazard risks.

International cooperation is encouraged, particularly in regions with cross-border infrastructure or shared vulnerabilities. Actions should take due account of the relevant EU legal and policy frameworks and are expected to address all applicable considerations expressed in the Introductions of the Resilient Infrastructure and Disaster-Resilient Society for Europe Destinations.

Coordination among the successful proposals from this topic and projects funded under HORIZON-CL3-2025-01-INFRA-01: Open topic for improved preparedness for, response to and recovery from large-scale disruptions of critical infrastructures and HORIZON-CL3-2025-01-INFRA-02: Open topic for role of the human factor for resilience of European critical entities, and HORIZON-CL3-2024-DRS-01-04: Hi-tech capacities for crisis response and recovery after a natural-technological (NaTech) disaster should be envisaged in order to avoid duplication, share resources and exploit complementarities and opportunities for increased impact.

HORIZON-CL3-2027-01-INFRA-01: Enhancing physical protection of critical infrastructures

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 6.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 12.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

The following additional eligibility conditions apply:

This topic requires involvement as beneficiaries of at least 3 relevant practitioners from EU Member States or Associated Countries. Depending on the specific proposal submitted, these practitioners should represent one or several of the following portfolios:

1.critical infrastructure operator,

2.authority responsible for critical infrastructure resilience,

3.civil protection authority,

4.law enforcement or private companies providing security for critical infrastructure.

For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 105 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following outcomes:

1.Critical infrastructure operators and authorities have improved physical risks and hazards assessment capabilities;

2.Perimeter security, access control, surveillance systems, remote sensors and other systems used by or relevant to critical infrastructure operators are capable of coping with threats from misuse of new and emerging technologies;

3.Improved operational procedures, including incidents management and training curricula, are developed;

4.Innovative solutions for critical infrastructure resilience are being developed, utilising recent advancements in spatial planning, security-by-design, preparedness-by-design and nature-based solutions using an inclusive approach that address diverse needs.

Scope: Physical protection of critical infrastructure should keep up its advancement to match risks and hazards stemming from malicious use of new and emerging technologies, and evolving operational environment, as well as improve its safety and security measures against knowns and emerging threats. Following this approach entities providing essential services should reduce their vulnerability, among others, to threats from improvised explosive devices, ramming attacks, sabotage, uncooperative and hostile unmanned platforms including swarm robotics, penetration of access points by unauthorised individuals and vehicles, unauthorised access to hazardous material storage, removal of critical components, or deterioration of critical infrastructure due to age, inadequate design or changed operational conditions, including climate.

Proposals submitted under this topic should identify and analyse possible new challenges for the physical security of the critical entities and develop adequate tools, recommendations, manuals and training programmes for relevant operators and authorities. Where relevant for their scope proposals should utilise the nature-based solutions and respect principles of biodiversity. Furthermore, solutions should take into account interdependencies in the context of supply chains and their impact on physical protection.

Coordination among the successful proposals from this topic and projects funded under HORIZON-CL3-2025-01-INFRA-01: Open topic for improved preparedness for, response to and recovery from large-scale disruptions of critical infrastructures and HORIZON-CL3-2025-01-INFRA-02: Open topic for role of the human factor for resilience of European critical entities, should be envisaged in order to avoid duplication, share resources and exploit complementarities and opportunities for increased impact.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

HORIZON-CL3-2027-01-INFRA-02: Impact of malicious use of Open-Source Intelligence on critical infrastructure business continuity

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.835 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 7.67 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

The following additional eligibility conditions apply:

This topic requires involvement as beneficiaries of at least 3 relevant practitioners from EU Member States or Associated Countries. Depending on the specific proposal submitted, these practitioners should represent one or several of the following portfolios:

1.critical infrastructure operator,

2.authority responsible for critical infrastructure resilience,

3.law enforcement or private companies providing security for critical infrastructure.

For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 106 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following outcomes:

1.Critical infrastructure operators and authorities have improved awareness of Open-Source Intelligence (OSINT) and their potential impact on security of their operations;

2.Toolbox for OSINT mapping, including enhanced analysis and risk flagging is developed and available to relevant stakeholders;

3.Critical infrastructure operators and authorities have improved incident response, emergency plans and business continuity models;

4.Removal of potentially harmful OSINT from the public domain in order to counter/prevent preparations and attempted attacks against critical entities, including the lone wolf and hybrid scenarios;

5.Awareness campaigns and training curricula for critical entities’ employees are developed.

Scope: The malicious use of Open-Source Intelligence (OSINT) is a known concern and technique used by offenders to retrieve personal, professional, and official or technical information about entities and their employees either to immediately plot illegal actions or use it to access more sensitive data with social engineering techniques like tailored data phishing. Although singular information may seem harmless, their critical mass coupled with reasoning and automated processing of large data blocks, could reveal critical vulnerabilities and possible attack vectors. This modus operandi is of special concern for critical infrastructure operators and authorities, as it can be used to aggregate sensitive information, identify potential protection gaps, discover the security measures, such as camera and sensor locations or target individuals with special access privileges in order to orchestrate more sophisticated and harmful attacks. OSINT can also be used to impede critical infrastructure operations indirectly, gathering information and affecting their supply chains.

Proposals submitted under this topic should analyse the type, amount and accessibility of publicly available information and their usefulness in planning hostile operations against critical entities and their services. They should also parse the role of OSINT for identification and recruitment of insiders, identity theft, impersonation, or launching psychological operations such as foreign information manipulation and interference or disinformation. Moreover, the implications of AI data processing to misuse OSINT potential should be addressed. Any potential OSINT sources should be covered including, but not limited to social media, online fora, cloud resources, public records and databases, lawfully accessible deep web and dark web data, geospatial information, as well as paper archives in the public domain with blueprints, emergency response plans or similar. Proposals should especially consider scenarios including hybrid threats and lone wolves and develop tools and awareness campaigns to mitigate such threats.

Proposals should build upon outcomes and tools of other relevant projects, adapting, optimising and integrating them when necessary to achieve the highest possible technology readiness level of the project results. The proposals funded under this topic are expected to engage with the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

Destination - Cybersecurity

Cybersecurity is essential for safeguarding Europe’s digital sovereignty, resilience, and technological leadership. The Horizon Europe Work Programme for Cybersecurity 2026-2027 builds on the broader EU strategic vision for cybersecurity as articulated in the EU Cybersecurity Strategy for the Digital Decade and contributes directly to the implementation of major initiatives including the Cyber Resilience Act, NIS2 Directive, Cyber Solidarity Act, AI Act, and the EU Quantum Strategy. It complements the deployment-focused Digital Europe Cybersecurity Programme, ensuring continuity from research and innovation to operational capability across the cybersecurity ecosystem.

The Cybersecurity actions proposed under this destination as described in the Annexes, are designed to reinforce the EU’s ability to detect, prevent, and respond to cyber threats, including those targeting critical infrastructure. Furthermore, they contribute to Europe's open strategic autonomy by supporting the development of trustworthy digital infrastructures, emerging technologies, cybersecurity capabilities, and secure supply chains.

The strategic plan 2025-2027 identifies the following impact: "Increased cybersecurity and a more secure online environment by developing and using effectively EU and Member States’ capabilities in digital technologies supporting protection of data and networks aspiring to technological sovereignty in this field, while respecting privacy and other fundamental rights; this should contribute to secure services, processes and products, as well as to robust digital infrastructures capable to resist and counter cyber-attacks and hybrid threats".

Under this Work Programme, the Commission intends to conclude a contribution agreement entrusting the European Cybersecurity Competence Centre (ECCC) with the implementation of call topics related to Increased Cybersecurity. Please refer to "Indirectly managed action by the ECCC" in the section "Other Actions" of this Work Programme part – including the Appendix providing the call specifications for information purposes. Those specifications incorporate ‘expected outcomes’ set out below.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Destination - Disaster-Resilient Society for Europe

Given the increasing frequency and ever greater impacts of disasters resulting from climate extremes, natural, geohazards and human-made hazards, the EU needs to invest more in improving disaster risk management, tools for disaster management 107 and societal resilience to avoid creating new exposure; reduce existing risk by building up resilience, prevention and preparedness; manage residual risk. In this respect, along the orientations given in the Horizon Europe strategic plan 2025-2027, the main objectives of this destination supporting the reduction of losses from natural, accidental and human-made disasters will be pursued in continuity with the strategic plan 2021-2024.

This destination will support the implementation of the European Commission political guidelines 2024-2029 for a ‘Safer and more secure Europe’, a ‘Preparedness Union’, with ‘Stronger Common Borders’, protecting democracy and putting research and innovation at the heart of a resilient economy. The European Preparedness Union Strategy 108 is a key document in its implementation. Overall, research under this Cluster should continue to focus on preserving and securing citizens’ basic right to feel safe. This destination will support the European Commission efforts towards:

1.enhancing efforts to prevent and prepare for new threats, especially those linked to chemical, biological, radiological and nuclear (CBRN) security.

2.continuing to address risks to security from climate change impact / step up work on climate resilience and preparedness.

3.supporting medical countermeasures against public health threats.

Moreover, this destination will support the implementation of UN Disaster Risk Reduction policies, the EU Disaster Resilience Goals 109 involving closer coordination with the Union Civil Protection Knowledge Network, the rescEU initiative and Member States’ civil protection authorities, as well as an enhanced dialogue at international level with the United Nations Office for Disaster Risk Reduction (UNDRR) on recommendations for the Sendai Framework 110 and United Nations Sustainable Development Goals (SDGs). Such closer coordination with other programmes will make it possible to further streamline future research programming. For example, Cluster 3 should focus on its core added value, which is a strong operational character for preparedness, crisis management, response and learning, while maintaining complementarities with broader prevention issues such as climate-related risks, covered by Cluster 5, and the Mission on Climate Change Adaptation. There are similar examples in closer coordination with Cluster 6 and the One Health approach, regarding, for instance, water and food security threats (as a result of intentional degradation or terrorist acts).

From a technological perspective, the Destination will ensure greater involvement of practitioners in close cooperation with the Member States and EU agencies, not only in research development and implementation, but also the identification of gaps and needs and future research topics. Actions to develop tools and technologies to meet operational capability needs should be aimed at higher technological readiness levels (TRLs). Finally, it will be important to take into account how research results, both those still to come and those already developed in past projects under the DRS destination, can be turned into deployable solutions by being combined with capacity-building programmes (in particular the Internal Security Fund, funding under the Union Civil Protection Mechanism 111 , the European Regional Development Fund, and the Cohesion Fund), and social innovation to support the entry into the market of developed technologies. Actions will also aim to ensure that there is a link between R&I and possible procurement (e.g., in the area of medical countermeasures).

Proposals for topics under this Destination should have the overarching objective of improving resilience. Actions will continue to explore initiatives and experiments involving the development of technological or methodological solutions for crisis management and support for emergency responders, getting the general public more involved in this area and improving interactions between regional and/or local authorities, public practitioners, private operators and civil society. Actions could also take into consideration human induced environmental disasters and regions vulnerable to extreme weather events in coastal areas, sea level rise and other climate change impacts, which may prone to disaster risks (e.g. the Arctic). New tools or solutions should build on what has been developed in past projects and be capable of being integrated into existing (legacy) systems. Actions will also focus on multi-service capability developments, in particular tools and technologies to support direct operational needs in case of a disaster. This will be done in a scalable way, covering areas from small rural towns to economically developed ones with a high population density, and opening research initiatives to international cooperation. Capabilities need to be upgraded to match the new resilience stakes and expectations of practitioners and of society as a whole. We should learn from past disaster events by identifying gaps in capabilities that the response to such events showed were lacking. For example, one of such gaps are the availability and distribution of medical countermeasures used to effectively respond to deliberate or accidental releases of CBRN-E substances.

The destination will continue to follow a multi-hazard approach, addressing disasters and threats of all kinds, including their cascading issues, climate-related or natural or human-made and geological hazards, industrial accidents, pandemics, intentional hostile acts including terrorism and armed conflict. Particular attention will be paid to floods and wildfires, as well as to chemical, biological, radiological, nuclear and explosive (CBRN-E) threats. To this end, proposals should contribute to the achievement of one or more of the following impacts:

1.Enhanced citizen and regional and/or local authorities' involvement in research actions, and in operational measures that may result from research, with focus on risk awareness and enhanced disaster prevention and preparedness, adapted to all types of disability (sensorial, physical, intellectual), including youth awareness raising and education;

2.Improved disaster risk governance (from prevention, preparedness to mitigation, response, deployment of countermeasures and recovery, using updated risk assessment methods and decision criteria, and including knowledge transfer and awareness of innovative solutions) from international to regional and/or local levels;

3.Strengthened capacities of disaster management systems for preventing, preparing for and responding to natural and human-made disasters in the spirit of Decision No 1313/2013/EU 112 including development of new prevention or preparedness technologies, infrastructures or assets as well as in support of field operations with validation of tools and technologies used in disaster responses including emergencies, and demonstration of their interoperability.

More precisely, in the context of exacerbated impacts of various disaster threats on vulnerable societies, research and innovation actions are highly needed to face the many challenges faced by European Society. Some of them are:

1.Challenges related to inclusion of the general public, regional and/or local communities and voluntary organisations as active partners in order to:

1.Empower citizens to act and help them to improve their disaster risk awareness and own resilience to crises, including accountability for regional and/or local administrative decisions on residual risks, youth awareness raising and education;

2.Provide all actors involved in the management of natural disasters, human-made emergency situations, and humanitarian crises with timely and accurate geo-spatial information derived from satellite remote sensing and completed by available in situ or open data sources in all phases of the emergency management cycle: preparedness, prevention, disaster risk reduction, emergency response and recovery, as well for early warning and in emergency situations;

3.Provide means for regional and/or local decision-makers and operational responders, i.e., first and second responders. A “second responder” is a worker who supports "first responders" such as police, fire, and emergency medical personnel. They are involved in preparing, managing, returning services, and cleaning up sites during and after an event requiring first responders, including crime scenes and areas damaged by fire, storm, wind, floods, earthquakes, or other natural hazards. These types of services may include utility services (shutdown or reinstatement of electrical, gas, sewage, and/or water services), wireless or wireline communication services, specialty construction (i.e. shelter construction), hazardous waste clean-up, road clearing, crowd control, emergency services (i.e. Red Cross 113 , first aid, food services, security services, social services (i.e., trauma counsellors), and sanitation, infrastructure owners, regional and/or local authorities (including public services, transport and utilities) to coordinate prevention and preparedness actions, bearing in mind the socio-economic and cultural context, and for operational responders to influence regional and/or local planning decisions that affect exposures and vulnerability to risks in short and long term;

4.Address citizens’ perception of, and involvement in, civil defence in the event of very large-scale disasters including armed conflict.

2.Challenges regarding the reinforcement of disaster risk governance and the consideration of knowledge and innovative solutions in order to:

1.Improve operational management of crises at different levels (prevention, preparedness, response, recovery) and scales (international to regional and/or local),

2.Reinforce the uptake and transfer of knowledge to risk managers, first and second responders and decision-makers;

3.Strengthen resilience and enhancing protection strategies for emergency services and healthcare workers in case of disasters;

4.Reinforce civil defence capability, looking at all facets of crisis and disaster management, alongside community resilience building;

5.Enhance preparedness for optimised detection, prevention, response and control measures in case of bioterrorism or emerging diseases.

3.Challenges related to wildlife- and domestic animals protection against disasters.

4.Challenges related to the validation and usability of tools and technologies, including the demonstration of their interoperability, in the context of strengthened cross-sectorial disaster management capacities as to:

1.Enhance risk awareness, preparedness and communication about foreseeable impacts of disasters;

2.Deploy innovative solutions in emergency situations including trusted communication channels (considering the upcoming proposal for a European Critical Communication System), emergency medical response, including triage of victims, pre-hospital and clinical services, medical countermeasures, support equipment (e.g. detectors), as well as protection of first responders;

3.Coordinate and further develop awareness and early systems for floods, wildfires, droughts, etc., considering Earth observation and modelling (Including the Copernicus Emergency Management Service), space communication (IRIS2), space navigation (Galileo and the Galileo EWSS Early Warning Satellite System), while ensuring alignment with the technical and scientific requirements to guarantee interoperability;

4.Enhance validation of tools, technologies and processes for cross-border prevention, decision-support and responses to climate-related and geological disasters and emergency crises by different practitioner sectors (firefighters, medical emergency services, civil protection, police, NGOs);

5.Enhance interoperability of tools and technologies used in international emergency (real-case) situations related to natural hazards, CBRN-E threats and hybrid threats via inputs such as standard operating procedures for foresight, risk analysis or guidance with the aim to improve market uptake.

This Destination will also support, whenever appropriate and applicable, the proposals with some or all of the following goals:

1.a clear strategy from international to regional and/or local on how the overall society will adapt to the evolving disaster risks based on the subsidiarity principle (from the citizen level to international decision-making);

2.the involvement of different disaster risk management stakeholders and regional and/or local authorities in research, development and validation of methods and tools;

3.the active role for Non-Governmental Organisations (NGOs) and Civil Society Organisations (CSOs);

4.the active involvement of Small and Medium Enterprises (SMEs);

5.a robust plan on how they will build on the relevant predecessor projects, and clustering with existing research (EU and national) actions to maximise complementarities and synergies and avoid duplication of efforts;

6.education and training aspects for first and second responders for different types of threats (climate-related, geohazards, accidental, intentional), and adapted to all types of disability (sensorial, physical, intellectual, as well as information sharing and awareness raising of the citizens;

7.a clear strategy on the uptake of the outcomes, defined in consultation with the involved stakeholders, taking into consideration the final users and the usability of the outcomes after the end of the project;

8.a well-developed plan both on how research data for training and testing will be obtained, in order to reach the requested Technology Readiness Levels (TRLs), and on how the specific TRL will be measured.  

Where possible and relevant, synergy-building and clustering initiatives with successful proposals in the same area should be considered, including the organisation of international conferences in close coordination with the Community for European Research and Innovation for Security (CERIS) 114 activities and/or other international events.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Proposals are invited against the following topic(s):

HORIZON-CL3-2026-01-DRS-01: Designing new ways of risk awareness and enhanced disaster preparedness

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 6.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Due to the scope of this topic, relevant international organisations with headquarters in a Member State or Horizon Europe Associated Country are exceptionally eligible for funding.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 3 organisations from at least 3 different EU Member States or Associated Countries as follows: (i) at least one civil society organisation (CSO); (ii) at least one authority in charge of disaster risk 115 (iii) at least one organisation representing local or regional authorities. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 5 by the end of the project – see General Annex B

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 116 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Development of innovative tools and methodologies to monitor and improve risk awareness across society, integrating diverse community perspectives and leveraging advanced technologies;

2.Development and uptake solutions and tools for the successful increase of safety culture and societal resilience of communities with concrete material, while considering also the inclusion and protection of marginalized populations in disaster scenarios;

3.Creation of comprehensive, inclusive preparedness plans that involve all societal sectors and governance levels, ensuring coordinated and effective responses to disasters (such as from early warning to early action), including scarcity of resources;

4.Establishment of a resilient, adaptive response framework that enhances collaboration between public authorities, communities, and private sectors, improving overall disaster resilience.

Scope: Building on the whole-of-society and whole-of-government approach, this topic should contribute to enhancing risk awareness and disaster preparedness through the development of innovative tools, methodologies, and frameworks. A key focus should be on integrating diverse societal and resilience perspectives considering people in a vulnerable situation, ensuring inclusive participation in risk communication strategies, and leveraging accessible advanced technologies and processes to improve public understanding of hazards and vulnerabilities (such as gender, disabilities and others social factors. and capabilities. Efforts should aim at designing and validating novel approaches to risk perception, communication, including digital platforms, immersive technologies, and participatory tools that foster citizen engagement and behavioural change, as well as wildlife protection. Behavioural insights should inform the projects on effective methods in population’s preparedness including the risk communication. Special attention should be given to marginalized or vulnerable groups in a vulnerable situation ensure equitable access to risk information and preparedness resources.

To strengthen disaster preparedness and response capabilities across Europe, there is a clear need for an innovative, interoperable solution that enables the development of new strategies for risk awareness and disaster management. Such a solution should facilitate seamless collaboration between public authorities, civil society, local communities, and the private sector. It must support the co-creation of comprehensive preparedness plans that ensure a coordinated, robust, resilient, and effective response to a wide range of disaster scenarios. Central to this approach should be the integration of a command-and-control system that allows for centralized information management, efficient coordination among all stakeholders, and rapid, data-driven decision-making in emergency situations. For example, efforts to guarantee early action from early warning should be taken into account.

Furthermore, proposals should work towards the creation of comprehensive, multi-stakeholder preparedness plans that involve all levels of governance, civil society, the private sector, and local communities. These plans should establish mechanisms for cross-sectoral coordination, efficient resource allocation, and effective decision-making in crisis situations and the development of solutions and tools to ensure a greater culture of safety and societal resilience in the communities. Research should also explore innovative governance models that enhance interoperability and cooperation between different entities. To strengthen disaster resilience, proposals should develop and test adaptive response frameworks that enhance collaboration between public authorities, civil society, communities, and businesses. These frameworks should incorporate near real-time risk assessment tools, digital simulations, and scenario-based exercises to improve the capacity to anticipate, respond to, and recover from disasters. The integration of AI-driven decision-support systems, taking into account existing biases, digital twin technologies (including Destination Earth), and predictive analytics could further contribute to a more effective, evidence-based crisis response.

Projects are expected to contribute to the overall enhancement of societal resilience by fostering a culture of preparedness, strengthening community-driven disaster risk reduction initiatives, proactive engagement in prevention- and mitigation of disaster’s effects, and ensuring that all actors within society have the necessary tools and knowledge to respond effectively to future crises.

Where relevant, projects may take into account the assets, but also particular challenges faced by the European outermost regions and may include entities from these regions in the consortium’s composition.

Projects should conduct a stakeholder or market analysis and a roadmap or plan for uptake of the developed methodologies, findings, and technologies to the industry, the research and innovation community, and/or the relevant authorities.

International cooperation in this topic is strongly recommended. Proposals should also take into account lessons learned from past disasters and align with existing EU policies, frameworks, and international commitments in the field of disaster risk reduction and crisis management. Especially the population preparedness chapter of the Preparedness Union Strategy, such as the preparEU initiative, should be considered. Finding synergies with projects from operational grants, such as the Knowledge for Action in Prevention & Preparedness (KAPP) 117 , is recommended.

HORIZON-CL3-2026-01-DRS-02: Multi-hazard approach and cumulative / cascading impacts

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Due to the scope of this topic, relevant international organisations with headquarters in a Member State or Horizon Europe Associated Country are exceptionally eligible for funding.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 authorities in charge of disaster risk or crisis communication 118 and 2 representatives of local or regional authorities in charge of disaster response from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 119 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Integrated single-hazard systems into multi-hazard next generation predictive models to assess cascading effects (e.g., heatwave, floods, droughts, landslides, heavy rain) and interactions across meteorological, geophysical, and technological hazards;

2.Enhanced hazard forecasting and response through research on model integration and platform interoperability;

3.Development of holistic risk and resilience metrics to support multi-hazard prevention strategies, encompassing main physical, economic and social effects;

4.Improvement of analysis models considering evolving vulnerability state, due to cascading and cumulative effects, through numerical simulations and experimental tests, possibly also supported by AI applications;

5.Collected reliable data (same granularity and format) and ways to share and analyse it. The interoperability of all kinds of systems and information sharing is crucial, based on the need-to-know principle;

6.Improved knowledge/experience-sharing from past emergencies to cope with future emergencies, also strengthening trans-national knowledge and data exchange among EU countries as well as from early warning to early action;

7.Improved disaster risk and resilience management due to single/multiple threats through a holistic, systemic and cross-cutting approach, also considering relevant changes such as changing climate, digital transformation, environmental and socio-economic conditions;

8.Development of holistic Risk and Resilience Metrics to support multi-hazard prevention strategies, encompassing main physical, economic and social effects;

9.Solutions shall include the analysis of the physical, social and governance systems and take into account the development of an EU comprehensive risks and threats assessment.

Scope: Advancing multi-hazard risk assessment and disaster resilience is a necessity. Building on the integrated all-hazard approach, the advancement will be achieved by integrating single-hazard models into next-generation predictive systems capable of analysing cascading and cumulative effects. A key focus should be on early and anticipatory action, improving the understanding of interactions between meteorological, geophysical, and technological hazards, including their compounding impacts on societies, economies, and critical infrastructure.

Proposals should aim to develop and validate integrated forecasting models, that enhance the prediction and management of multi-hazard scenarios, supports flexibility and extensibility, and coordination of responses by incorporating real-time data, AI-driven analytics, and remote sensing technologies. These models should facilitate improved hazard forecasting by addressing challenges in platform interoperability and data exchange, ensuring that diverse hazard monitoring systems at local, national, and global levels can effectively communicate and operate in synergy.

Efforts should also explore the interoperability of regional and national hazard warning systems, enhancing global forecasting capabilities for hazards such as landslides triggered by extreme weather events, or cumulative damage modelling for earthquakes and their aftershocks. Research should address gaps in loss estimation models by considering the cascading and long-term impacts of disasters on infrastructure, the built environment, supply chains, and diverse needs of communities. Furthermore, proposals should contribute to the development of advanced tools and methodologies to assess the combined effects of multiple hazards on critical infrastructure, ensuring that disaster risk management strategies account for interdependencies across sectors This should include scenario-based stress testing, digital twins for risk modelling, and AI-powered decision-support systems, taking into account existing biases, to enhance resilience planning for lifeline services such as energy, water, transport and telecommunications.

A holistic, systemic, and cross-cutting approach should be applied to disaster risk management, taking into consideration climate change trends, environmental degradation, and vulnerabilities such as gender, age, disabilities and others social factors. The topic should lead to the creation of comprehensive Risk and Resilience Metrics, integrating physical, economic, and social dimensions to support decision-makers in designing effective prevention and adaptation strategies. Considering building on and leveraging from existing systems, such as the Copernicus Emergency Management Service (CEMS) the Destination Earth Platform or Risk Data Hub, could be beneficial.

Projects should conduct a stakeholder or market analysis and a roadmap or plan for uptake of the developed methodologies, findings, and technologies to the industry, the research and innovation community, and/or the relevant authorities.

Projects may take into account the assets but also particular challenges faced by the European outermost regions and may include entities from these regions in the consortium’s composition.

Projects should contribute to strengthening risk governance at multiple levels by fostering collaboration between scientific communities, policymakers, emergency responders, and infrastructure operators. Efforts should be made in leveraging citizens-generated content in social media and decentralised digital platforms for citizen-driven early warning and situational awareness. Alignment with EU policies, international risk reduction frameworks, and best practices in resilience planning should be ensured, maximizing the applicability and impact of the developed solutions. The Preparedness Union Strategy is a key document in this regard and includes a key action on developing an EU comprehensive risks and threats assessment. Finding synergies with projects from operational grants, such as the Knowledge for Action in Prevention & Preparedness (KAPP) 120 , is recommended.

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud, as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

HORIZON-CL3-2026-01-DRS-03: Development of innovative tools, processes, equipment and technologies through responses to disasters and emergencies for search and rescue in hazardous conditions

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

Due to the scope of this topic, relevant international organisations with headquarters in a Member State or Horizon Europe Associated Country are exceptionally eligible for funding.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 practitioner organisations (first responders) and 2 medical emergency authorities from at least 3 different EU Member States or Associated Countries.

For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 7-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 121 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Creation of cutting-edge tools, processes, equipment and technologies to enhance disaster and emergency response capabilities for various practitioners as well as for assets, such as vehicles, aircraft, and heavy equipment;

2.Taking into consideration existing technologies, development of autonomous drones, robotics, and other technologies specifically designed for emergency medical response and search and rescue operations in hazardous conditions such as wildfires, earthquakes and large-scale events;

3.Improvement of response efficiency and safety for survivors and emergency practitioners through the adoption of advanced, technology-driven solutions in disaster scenarios;

4.Consider needs of existing EU-level capacities, emergency reserves, and stockpiling in the deployment of the assets and being able to move them.

Scope: The scope of this topic is the development of innovative tools, equipment, and technologies to enhance the capabilities of emergency responders operating in complex and hazardous disaster environments. By leveraging advancements in smart protective equipment, in robotics, autonomous systems, remote sensing, communication and human sensor technologies, the aim is to improve the efficiency, safety, and effectiveness of emergency medical response and search and rescue operations, particularly in high-risk scenarios, such as wildfires, earthquakes and large-scale trauma events.

Proposals should explore the design, testing, and validation of innovative solutions capable of performing critical tasks in disaster-stricken areas. These technologies should be tailored to operate in extreme conditions, including high temperatures, unstable terrains, and low-visibility environments and beneficial to all individuals regardless of their age, gender or ability. Research should address challenges related to autonomous navigation, AI-driven decision-making, real-time situational awareness, and seamless integration with existing command-and-control systems used by disaster management. Collaboration of different practitioners should be supported to support proper market uptake.

Efforts should be made to enhance interoperability and data-sharing capabilities between various platforms, emergency response teams, and crisis management systems. A key aspect of this research should be the practical deployment and validation of these technologies through field exercises and simulations in real-world disaster scenarios. User-driven design approaches, prioritising inclusivity and accessibilities should ensure that developed solutions align with the operational needs of responders in disasters., Proposals should develop a command-and-control solution that allows organisation of all activities, ensuring a swift, coordinated, and effective response to any disaster with clear plan for uptake after the project.

Projects should conduct a stakeholder or market analysis and a roadmap or plan for uptake of the developed methodologies, findings, and technologies to the industry, the research and innovation community, and the relevant authorities. The current response capacities of the European Civil Protection Pool 122 its capacity gaps 123 , and the rescEU strategic reserve 124 as well as the EU Stockpiling Strategy should be taken into account in the roadmap to ensure needs-based approach. Thus, the proposals could consider innovation for heavier assets, such as flood containment and high-capacity pumping, transport or response aircraft, shelters and power generators, ground firefighting vehicles and aerial firefighting helicopters.

Furthermore, proposals should consider ethical, legal, and social implications associated with the deployment of autonomous technologies in emergency response. Issues such as data privacy, cybersecurity, human- and animal life protection, public acceptance, and compliance with regulatory frameworks should be addressed to facilitate the responsible and effective use of these innovations.

Projects should contribute to strengthening Europe’s disaster response capacity by equipping practitioners with state-of-the-art technological solutions that enhance their ability to operate safely and efficiently in life-threatening environments. Alignment with EU policies and international best practices should be ensured to maximize the scalability and real-world applicability of the developed solutions. The Preparedness Union Strategy is a key document in this regard. Finding synergies with projects from operational grants, such as the Knowledge for Action in Prevention & Preparedness (KAPP) 125 , is recommended.

HORIZON-CL3-2026-01-DRS-04: Open topic on driving innovation uptake of disaster risk solutions

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 6.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 3 first responders or authorities in charge of disaster risk 126 from at least 3 different EU Member States or Associated Countries.

For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 127 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Accelerated adoption of high-TRL (Technology Readiness Level) disaster risk solutions across diverse sectors;

2.Facilitated integration of innovative technologies into existing disaster prevention, preparedness, response, and recovery frameworks;

3.Promoted collaboration among stakeholders to scale proven solutions and enhance resilience;

4.Addressed barriers to deployment, ensuring accessibility and usability of advanced DRS technologies;

5.Strengthened evidence-based decision-making through demonstration and validation of high-TRL solutions in real-world scenarios;

6.Promoted visibility of civil security research results.

Scope: This topic aims to foster the widespread adoption and integration of high-TRL (Technology Readiness Level) disaster risk solutions (DRS) across multiple sectors, enhancing societal resilience to various hazards, including climate. The focus is on overcoming barriers to deployment, ensuring accessibility, and strengthening collaboration among stakeholders to drive innovation uptake. Projects should promote the adoption of high-TRL solutions by public and private sector organizations involved in disaster risk management, developing strategies for scaling and commercializing innovative DRS technologies to ensure they reach end-users efficiently. They should also demonstrate how these technologies can complement or replace existing disaster preparedness, response, and recovery frameworks by developing integrated governance and coordination models across sectors and levels for disaster preparedness, response, and recovery in multi-hazard and cascading risk scenario interoperability standards, and guidelines for integrating new solutions into national and European civil protection systems. The project should especially liaise and support other disaster resilience projects in driving their uptake as well as examine how to build synergy pathways with other preparedness grants, such as Knowledge for Action in Prevention & Preparedness (KAPP) funding call of the Union Civil Protection Mechanism (UCPM).

Addressing deployment barriers is crucial, including identifying and mitigating technical, regulatory, financial, and social obstacles hindering the uptake of advanced solutions, while ensuring accessibility and usability for diverse stakeholders such as first responders, local authorities, and communities and individuals in a vulnerable situation. Projects should also demonstrate the real-world effectiveness of high-TRL solutions through large-scale pilot projects and demonstrations, generating robust evidence to support data-driven decision-making and optimize disaster risk reduction strategies. Initiatives should consider the capacity gaps of the UCPM 128 , align with EU disaster resilience objectives and build on existing programs, ensuring synergies with relevant policies, funding mechanisms, and technological ecosystems. The private-public cooperation chapter of the Preparedness Union Strategy should especially be a guiding document. Proposals are encouraged to incorporate digital tools, AI-driven analytics, digital twins such as Destination Earth, IoT applications, and other emerging technologies to enhance disaster preparedness and response.

Proposals should have a strategy to promote the visibility of the project and the results to the broader public in order to show the potential of European civil security research (political sphere, private sector, citizens). This could entail the European Civil Protection Forum and the European Commission Disaster Risk Management Knowledge Centre platform as examples.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

HORIZON-CL3-2026-01-DRS-05: Climate security and civil preparedness – new ways to develop pre- and post-crisis climate-change related scenarios for a more resilient Europe

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 4.50 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Due to the scope of this topic, relevant international organisations with headquarters in a Member State or Horizon Europe Associated Country are exceptionally eligible for funding.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 3 authorities in charge of disaster risk 129 from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 7-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 130 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Identification and prioritization of climate security scenarios, assessing cascading and compounding risks across multiple sectors;

2.Development and validation of advanced tools, technologies, and data-driven solutions for climate - and environmental - risk forecasting, crisis management, and adaptation, including risk analytical and assessment tools, weather alerts and forecasts;

3.Development and validation of advanced tools and technologies to assess and monitor climate-induced disasters, also providing risk information on adaptation and risk reduction measures;

4.Strengthened engagement with stakeholders, ensuring end-user involvement in defining requirements, testing, and validation of climate security solutions;

5.Development and validation of new risk-management tools, technologies and data, closer to operational environment. Focus on local and regional risk-management and climate adaptation work should be prioritized;

6.Pre-crisis analysis and post-crisis situational awareness in case of those disasters related to climate change (floods, fires, landslides, heat waves, etc.);

7.Enhanced international cooperation, policy integration, and public awareness to improve climate security resilience and preparedness. Strengthen networks to exchange best practices and support the international dimension of the Preparedness Union Strategy and the Sendai Disaster Risk Reduction Framework.

Scope: Climate change is a global challenge with profound security implications at the global, regional, and local levels. It exacerbates risks across multiple sectors, including agriculture, biodiversity, health, border security, economy, financial stability, transport, telecommunication and human displacement, leading to severe socio-economic consequences and destabilizing communities. The increasing frequency and intensity of climate-related disasters highlight the urgent need for a holistic, long-term strategy to address climate security, integrating risk assessment, crisis management, and adaptation measures, while also leveraging the expertise of the insurance sector.

While climate services based on data analysis have reached a high level of trust among users, their application to civil security remains underdeveloped. Proposals should aim to develop methodologies, tools, and technologies that enhance situational awareness both before a crisis (pre-crisis) and after a crisis (post-crisis), enabling decision-makers and populations to respond effectively. Research should focus on defining priority climate security scenarios in the EU, identifying key stakeholders, and establishing essential indicators for informed decision-making.

Efforts should be directed toward understanding and mitigating the impacts of floods, landslides, wildfires, and other climate-induced disasters. This includes developing improved methods and models for risk prevention and reduction, early detection, emergency response tactics, and rescue efforts under extreme conditions. The study of cascading effects and compounding disasters is critical, particularly regarding groups in a vulnerable situation such as older people, people with disabilities, and children. In this view, the proposals should build on the European Climate Risk Assessment (EUCRA 131 ) and consolidated national risk assessments 132 as well as find synergies with project’s chosen for the similar EU Mission: Adaptation to Climate Change topic 133 . Both the European Preparedness Union Strategy, the European Water Resilience Strategy and the upcoming European Climate Adaptation Plan act as policy guidance.

Diverse climate and environmental security scenarios should be developed, supported by innovative, reliable tools that leverage multiple data sources, enabling a comprehensive and adaptive response. Proposals should also integrate space programme components such as Copernicus and Galileo to improve data accuracy and crisis response capabilities. A strong emphasis on international cooperation should foster knowledge exchange, enhance policy integration, and share best practices. Proposals should support transnational collaboration within the EU, facilitate improved data-sharing mechanisms, and align with global initiatives such as the Sendai Disaster Risk Reduction Framework. Capacity-building efforts to strengthen resilience to climate-related security threats and ensure a coordinated approach to addressing worst-case climate scenarios, as identified in the Niinistö report 134 .

Projects may take into account the assets but also particular challenges faced by the European outermost regions and may include entities from these regions in the consortium’s composition.

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud, Copernicus, Destination Earth, as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

Where relevant, funded projects are encouraged to liaise with the European Commission's Joint Research Centre, for complementary real-scale testing at the Reaction Wall and HopLab of the European Laboratory for Structural Assessment (ELSA).

HORIZON-CL3-2027-01-DRS-01: Open Topic on advanced protective gear optimized for CBRN-E (Chemical, Biological, Radiological, Nuclear, Explosives) environments and new generation of smart protective equipment for disaster responders

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.835 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 7.67 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of:

1.at least 2 Training Centres 135 located in EU Member States or Associated Countries, and

2.at least 2 practitioners involved in training, validation and testing of CBRN-E tools and technologies from at least 2 EU Member States or Associated Countries.

For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 7-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 136 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Developed of advanced protective gear specifically designed for optimal performance in Chemical or Biological or Radiological, and Nuclear or Explosives (CBRN-E) environments;

2.Created innovative smart protective equipment for disaster responders, incorporating advanced technologies to enhance safety and operational efficiency;

3.Improvement of protective solutions to ensure the safety and effectiveness of disaster responders operating in hazardous and high-risk environments.

Scope: This topic aims to advance the development of protective gear specifically designed for optimal performance in specificities of the Chemical, Biological, Radiological, Nuclear, and Explosives (CBRN-E) environments, along with the creation of a new generation of smart protective equipment for disaster responders. Projects should focus on the use of innovative materials, technologies, and design features that enhance the protective capabilities of gear used in high-risk, hazardous environments, ensuring the safety and well-being of disaster responders with an inclusive and user-centric approach. The integration of advanced technologies will be crucial to enhancing the operational efficiency and effectiveness of the equipment.

Projects should conduct a stakeholder or market analysis and a roadmap or plan for uptake of the developed methodologies, findings, and technologies to the industry, the research and innovation community, and/or the relevant authorities. The current response capacities of the European Civil Protection Pool 137 and the rescEU strategic reserve 138 should be taken into account in the roadmap to ensure needs-based approach.

Proposals should build upon existing research outputs, specifically under other Horizon Europe Cluster 4, and technologies to create smart, adaptive protective solutions that respond dynamically to evolving threats in CBRN-E scenarios. This includes the incorporation of features similar to automated hazard detection, environmental monitoring, and advanced communication systems to provide real-time situational awareness. The new gear should meet rigorous safety standards while improving the comfort, mobility, and usability of responders, enabling better performance and faster decision-making in demanding environments.

Proposals should focus on providing comprehensive solutions that combine robust protection, operational support, and data-driven insights, ensuring a holistic approach to safety. Collaboration between research institutions, manufacturers, and end-users will be essential to ensure that the resulting products meet the practical requirements of practitioners in the field. The Preparedness Union Strategy is a key document in this regard. Analysing the capacity gaps of the UCPM 139 as well as finding synergies with the rescEU strategic reserve and projects from operational grants, such as the Knowledge for Action in Prevention & Preparedness (KAPP) 140 , is recommended.

HORIZON-CL3-2027-01-DRS-02: Societal resilience, engagement of the younger generations and digital innovation for disaster resilience

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 6.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 Civil Society Organisation (CSO) and 2 NGOs representing young people or youth organisations from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 141 .

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Developed a tailored education programs for younger generations, incorporating digital tools and gamification to enhance disaster awareness and engagement;

2.Strengthened societal resilience by actively involving younger generations, citizens, and local authorities in disaster preparedness and response initiatives;

3.Promoted collaborative research that integrates youth perspectives and community involvement, fostering a more resilient society in the face of disasters and crises;

4.Enhanced resilience and behaviour of children, young people, and other groups in a vulnerable situation before, during, and after climate-related disasters and health emergencies;

5.Training and education tools to engage young people and other populations a vulnerable situation in preparedness and crisis management.

Scope: This topic focuses on enhancing societal resilience by actively engaging younger generations in disaster preparedness, response, and recovery through digital innovation, education, and community involvement. Projects should develop tailored innovative solutions that integrate digital tools, gamification, and interactive learning methods to improve disaster awareness, risk perception, and response capabilities among younger generations. These initiatives should empower younger generations 142 , to become active contributors to resilience-building efforts, equipping them with the knowledge and leadership skills.

Particular attention should be given to the behaviour of children, young people, and other groups in a vulnerable situation before, during, and after climate-related disasters and health emergencies. Participatory approaches, including youth-led initiatives, citizen science, and digital engagement platforms, should be prioritized to enhance community-based resilience and ensure young people’s perspectives are integrated into decision-making processes. These approaches should follow an intersectional approach that gives credit to the (growing) heterogeneity of young people. Best practices from other programmes should be taken into account.

Proposals should also focus on leveraging emerging technologies - such as artificial intelligence, virtual and augmented reality, social media analytics, and serious games - to engage young people in disaster preparedness and crisis response. Additionally, innovative communication strategies should be explored to enhance youth participation, particularly through digital technologies and social media. Practical examples, including pilots and real-world case studies, should be developed to test and refine these approaches.

Proposals should explore methods to interconnect young people’s data with crisis management teams, practitioners, and authorities, ensuring that their contributions are effectively integrated into emergency response frameworks. Training and education tools should be designed to engage young people and other vulnerable populations in preparedness and crisis management, promoting long-term resilience.

Projects should conduct a stakeholder or market analysis and a roadmap or plan for uptake of the developed methodologies, findings, and technologies to the industry, the research and innovation community, and/or the relevant authorities.

The support and involvement of citizens and civil society is central to achieving the targeted outcomes.

By fostering collaborative research and youth-driven initiatives, projects should contribute to innovative and inclusive resilience strategies that align with EU policies on disaster risk reduction, education, digital transformation, and civil protection. Proposals should ensure synergies with existing initiatives and frameworks, such as the Preparedness Union Strategy’s chapter on population preparedness, Erasmus+ and the European Solidarity Corps, as well as the Sendai Disaster Risk Reduction Framework. Finding synergies with projects from operational grants, such as the Knowledge for Action in Prevention & Preparedness (KAPP) 143 , is recommend.

HORIZON-CL3-2027-01-DRS-03: Enhancing decision support system for disaster crises: leveraging emerging technologies for improved civil preparedness and crisis management

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 9.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 authorities in charge of disaster risk or crisis communication 144 and 2 representatives of local or regional authorities in charge of disaster response, from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 7-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 145 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Development of decision support systems for disaster crises, utilizing near real-time data from the ground to enhance situational awareness and response;

2.Creation of systems designed to bolster civil preparedness, that enhance operational efficiency and response times, ensuring timely and effective management of various disaster scenarios including from early warning to early action

3.Integration of advanced data analysis and decision-making tools to support authorities and first responders in disaster situations.

Scope: This topic focuses on enhancing existing decision support systems for disaster crises by integrating emerging technologies to improve civil preparedness and crisis management. The objective is to advance the capabilities of existing systems, making them more reliable, adaptable, and efficient through the incorporation of trustworthy AI technologies that ensure transparency, accountability, and ethical decision-making processes. Projects should aim to enable quicker and more informed responses during disaster scenarios.

Proposals should focus on creating advanced systems designed to strengthen civil preparedness, helping authorities and responders manage various disaster situations in a timely and effective manner. These systems should leverage cutting-edge AI-driven tools to process large volumes of data, providing actionable insights that improve decision-making during critical moments, such as from early warning to early action. Emphasis should be placed on integrating advanced data analysis and predictive modelling to anticipate disaster developments and guide interventions, while ensuring that the systems are transparent, explainable, and built on principles of trustworthiness, inclusive and gender sensitive and ethical AI use and on secure AI deployments.

Projects should conduct a stakeholder or market analysis and a roadmap or plan for uptake of the developed methodologies, findings, and technologies to the industry, the research and innovation community, and/or the relevant authorities.

Additionally, test centres should play a key role in this research by increasing their capacity to trial and validate emerging technologies, supporting more effective civil preparedness and crisis response capabilities.

The expected outcome is to create systems that not only enhance operational efficiency and response times but also foster better collaboration among stakeholders, including local authorities, emergency services, and other relevant actors. This includes integrating drones with state emergency vehicles, smart traffic systems, and law enforcement to enhance data driven disaster preparedness and emergency response, ensuring effective coordination and faster decision-making for local authorities.

Projects should also contribute to improving the usability and accessibility of decision-support systems for diverse users, ensuring they are easily integrated into disaster management frameworks and can be used effectively in different crisis situations. The solutions should align with EU guidelines on AI ethics 146 and resilience-building, ensuring they complement existing civil protection and crisis management initiatives while driving innovation in disaster risk reduction. The Preparedness Union Strategy is a key document in this regard. Analysing the capacity gaps of the UCPM 147 and finding synergies with projects from operational grants, such as the Knowledge for Action in Prevention & Preparedness (KAPP) 148 , is recommended.

In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud, Copernicus, Destination Earth as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

HORIZON-CL3-2027-01-DRS-04: Enhancing preparedness for large-scale cross-border disasters

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 8.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

Due to the scope of this topic, relevant international organisations with headquarters in a Member State or Horizon Europe Associated Country are exceptionally eligible for funding.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 3 authorities in charge of disaster risk or crisis communication 149 , from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 150 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Utilization of virtual and augmented reality training to simulate large-scale and transboundary disasters, improving disaster management’s readiness and response capabilities;

2.Development of diverse crisis scenarios using VR/AR technology, providing immersive, practical training experiences for emergency personnel, responders and decision makers;

3.Strengthened ability of responders and decision-makers to manage large-scale, cross-border disaster scenarios through advanced, technology-driven training programs;

4.Improved knowledge/experience-sharing from past emergencies to cope with future emergencies, also strengthening trans-national knowledge and data exchange among EU countries as well as from early warning to early action.

Scope: The scope of this topic is on enhancing preparedness for large-scale, cross-border disasters by leveraging advanced training methodologies, including virtual reality (VR) and augmented reality (AR) simulations and Digital Twins. The objective is to improve the readiness and response capabilities of disaster responders and emergency management personnel by providing immersive, technology-driven training experiences that replicate complex disaster scenarios.

Proposals should develop and validate innovative VR/AR-based crisis simulation models that can accurately depict diverse large-scale disaster situations, including transboundary hazards such as wildfires, floods, earthquakes, and industrial accidents. These simulations should incorporate near real-time data, AI-driven scenario adaptation, and multi-user interaction capabilities to ensure realistic, high-impact training exercises. Special attention should be given to the interoperability of these training platforms, allowing emergency services from different regions and countries to collaborate in joint preparedness exercises. Recommendations taken into account a gender-sensitive approaches should also improve crisis simulations by considering diverse needs and experiences.

Research should also explore how digital training environments can enhance situational awareness, decision-making, and coordination among disaster management and relevant authorities. The integration of gamification techniques, AI-driven coaching systems, and real-time performance assessment should be considered to maximize learning outcomes and adaptation to evolving crisis scenarios linking to previous themes (e.g. biometrics and long-lasting disturbance, or whole of the society security, multi-hazard theme etc.).

Furthermore, proposals should focus on strengthening knowledge and experience-sharing mechanisms across EU member states by developing transnational training frameworks and crisis management protocols, in coordination with the UCPM Training Programme 151 . This should include the establishment of digital platforms and collaborative networks to facilitate the exchange of lessons learned from past emergencies, fostering continuous improvement in disaster response strategies.

Projects should conduct a stakeholder or market analysis and a roadmap or plan for uptake of the developed methodologies, findings, and technologies to the industry, the research and innovation community, and/or the relevant authorities.

Ethical, legal, and social aspects related to the use of immersive training technologies should also be addressed, ensuring compliance with data protection regulations and maximizing public trust in the adoption of these tools. Trust should also refer to the security of the tools, that should include appropriate measures for resilience against emerging cryptographic threats. Projects should align with existing EU disaster risk reduction policies and international best practices to ensure the practical applicability and scalability of the developed solutions. The Preparedness Union Strategy is a key document in this regard. Its key action on “Develop an EU catalogue for training and a platform for lessons learned” and existing platforms should be taken into account in the proposal. Analysing capacity gaps of the UCPM 152 and finding synergies with projects from operational grants, such as the Knowledge for Action in Prevention & Preparedness (KAPP) 153 , is recommended.

Where applicable, proposals should leverage the data and services available through European Research Infrastructures federated under the European Open Science Cloud, Copernicus, Destination Earth as well as data from relevant Data Spaces. Particular efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable).

Destination - Strengthened Security Research and Innovation

Since the Preparatory Action for Security Research 154 the EU-funded security research and innovation programme has contributed substantially to knowledge and value creation in the field of internal security. The programme has been fundamental to the consolidation of a European security ecosystem, which is better equipped to capitalise on research and innovation outcomes to support the EU security priorities. This Destination aims to contribute to reducing thematic fragmentation, bringing closer together the actors from different security domains, and expanding the market beyond traditional thematic silos. It also creates knowledge and value through research in matters (including technology, but also social sciences and humanities) that are not exclusive of only one security area, but cross-cutting to the whole Cluster.

As underlined in the Horizon Europe strategic plan 2025-2027, proposals for the topics under this Destination ‘should support with cross-cutting actions the expected impacts outlined above [in the Cluster 3 Destinations]. This destination will increase the impact of the work carried out in the EU security Research and Innovation (R&I) ecosystem and contribute to its core values, namely:

1.a focus on the potential and practical final use of the outcomes of security R&I;

2.forward-looking planning of EU security capabilities;

3.the development of security technologies that are socially acceptable, developed in quadruple helix 155 and that have added value for industrialisation, joint procurement, commercialisation, and the acquisition and deployment of successful R&I outcomes;

4.safeguarding the EU’s open strategic autonomy and technological sovereignty in critical security areas by contributing to a more competitive and resilient EU civil security technology and industrial base;

5.experimenting with research and innovation programming; and

6.helping to make the European R&I ecosystem more consistent’. 

Many of the programme outcomes have materialised in relevant scientific findings, maturation of promising technology areas, operational validation of innovative concepts or support to policy implementation. However, a key challenge remains in improving innovation uptake and thus contributing to the development of security capabilities 156 , support of Start-ups and Small-Medium Enterprises (SMEs) and deployment of innovation by security practitioners.

The extent to which innovative technologies developed thanks to EU R&I investment are industrialised and commercialised by EU industry, and acquired and deployed by end-users, could reflect the impact achieved with the programme. As explained in the Commission staff working document on Enhancing security through research and innovation 157 there are factors inherent to the EU security ecosystem (often attributed to the market) that hinder the full achievement of this impact, such as market fragmentation, cultural barriers, analytical weaknesses, programming weaknesses, ethical, legal and societal considerations or lack of synergies between funding instruments, among others. To that aim, there is a need to create a favourable environment that is designed with the main purpose of increasing the impact of security R&I, which provides the right tools that serve to tackle the factors that hinder innovation uptake.

Therefore, security research and innovation should foster and enhance the development of innovative tools, technologies and capabilities for the benefit of practitioners that can use in their day-to-day work. To this end, proposals under this Destination should set out a credible pathway to contributing to the following impacts:

1.A more effective and efficient evidence and knowledge-based development of EU civil security capabilities built on a stronger, more systematic and analysis-intensive security research and innovation cycle;

2.Increased cooperation between demand and supply market actors, including with actors from other domains, fosters swift industrialisation, commercialisation, adoption and deployment of successful outcomes of security research and reinforces the competitiveness and resilience of EU security technology and industrial base and safeguards the security of supply of EU-products in critical security areas;

3.R&I-enabled knowledge and value in cross-cutting matters reduces sector specific bias and breaks thematic silos that impede the proliferation of common security solutions.

This Destination will trigger actions that will help bringing these and other developments closer to the market, thus contributing to the measures facilitating the uptake of innovation. Those actions will help developers (including industry, research organisations and academia) to accelerate product development and improve the valorisation of their research investment. They will also support buyers and users in materialising the uptake of innovation and further develop their security capabilities. The aim is to increase the capacity of EU public procurers to align their requirements with the EU security industrial capacity and to attract innovation and innovators from security and other sectors through common validation strategies, rapid innovation, experimentation and pre-commercial procurement.

Finally, this Destination will contribute to the development of the tailored analytical capacity required for the adoption of capability-driven approaches aimed at fostering a forward-looking capability-driven approach in security.

Where possible and relevant, synergy-building and clustering initiatives with successful proposals in the same area should be considered, including the organisation of international conferences in close coordination with the Community for European Research and Innovation for Security (CERIS) 158 activities and/or other international events.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Proposals are invited against the following topic(s):

HORIZON-CL3-2026-01-SSRI-01: Open topic on supporting disruptive technological innovations for civil security

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 2 relevant practitioners and 1 Research and Technology Organisation (RTO). For participants with practitioner status, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 4-5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 159 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Improved preparedness, evidence-based approaches and response capabilities, along with a strengthened ability to mitigate risks from diverse threats, by integrating validated disruptive technologies into real-world operations;

2.Accelerated adoption of innovative solutions by reducing barriers through rigorous testing and validation, fostering collaboration among public authorities, industry, and researchers to align technologies with real-world needs.

Scope: This topic aims to support the integration of disruptive technological innovations 160 into civil security by strengthening research and innovation activities that enhance preparedness, response capabilities, and risk mitigation. A key focus is bridging the gap between early-stage, low Technology Readiness Level (TRL) research and applied security solutions, ensuring that emerging technologies are effectively transitioned into operational use.

Proposals should prioritize disruptive solutions that address diverse security threats while improving the efficiency and effectiveness of civil security operations. Emphasis should be placed on ensuring that these technologies are robust, reliable, scalable, and aligned with the needs of security practitioners. This includes fostering a structured pathway for transitioning low TRL innovations into practical applications, ensuring rigorous testing and validation processes for safety, performance, and interoperability.

To achieve this, proposals should promote strong collaboration between researchers, public authorities, industry partners, and end-users. Such partnerships will help align technological advancements with real-world security needs, facilitating the co-development of solutions that are both innovative and operationally relevant. Ensuring that emerging technologies are ethically sound, transparent, and accessible will also be crucial to their successful adoption.

The expected outcomes of this topic include improved preparedness through the adoption of cutting-edge technologies tailored to emerging security challenges, enhanced risk mitigation capabilities, and the accelerated integration of disruptive innovations into civil security frameworks. By fostering a collaborative ecosystem, projects should ensure that promising research transitions effectively into practical security applications, contributing to a more resilient and adaptive civil security landscape across Europe.

To ensure that the proposed research and innovation activities are aligned to EU long-term strategic priorities, proposers are encouraged to consult relevant technology foresight exercises 161 .

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Strengthened Security Research and Innovation Destination.

HORIZON-CL3-2026-01-SSRI-02: Demand-led innovation in security

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 5.83 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.83 million.

Type of Action

Pre-commercial Procurement

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the participation 162 , as beneficiaries, of at least 3 practitioners and 3 public procurers 163 . These beneficiaries must be from at least 3 different EU Member States or Associated Countries. One organisation can have the role of practitioner and public procurer simultaneously, both counting for the overall number of organisations required for eligibility. Among the public procurers 164 , minimum two must be independent legal entities that are public procurers, each established in a different Member State or Associated Country and with at least one of them established in a Member State.

For participants with practitioner status, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

PCP/PPI procurement costs are eligible.

The specific conditions for actions with PCP/PPI procurements in section H of the General Annexes apply to grants funded under this topic.

Beneficiaries must ensure that the subcontracted work is performed in at least 3 Member States — unless otherwise approved by the granting authority.

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants / prizes. The maximum amount to be granted to each third party is EUR 100 000 to provide financial incentives to final end-users that are not part of the consortium (e.g., citizens) to adopt the solutions, including costly hardware components.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.A community of EU civil security practitioners with common user/functional needs for innovative technology solutions is identified, supported by an industrial base, in particular SMEs and Startups, to access the public procurement market and scale up their business;

2.Procurers facilitated the commercialisation of the innovative solutions developed by their successful suppliers by providing them with first customer references for the validation and first pilot deployment;

3.Tested and validated capacity of EU technology and industrial base to develop and produce technology prototypes that meet the diverse needs of the EU user community, regardless of their gender, age and ability;

4.Improved delineation of the EU market (including demand and supply) for innovative civil security systems that can articulate alternative options for uptake in function of different industrialisation needs, commercialisation needs, acquisition needs, deployment needs and additional funding needs (beyond R&I funding).

Scope: As past experience shows that pre-commercial procurement opens up the procurement market for startups and enables the public sector to address societal challenges more effectively, public procurers should make more strategic use of PCP. Applicants are invited to submit proposals for PCP action to acquire Research and Development (R&D) services and innovative civil security technology solutions.

Proposals should demonstrate interest from a broader community of potential buyers, beyond the direct beneficiaries, who share similar needs and are open to jointly adopting the solutions developed, provided they are proven mature and operationally viable. The proposals are expected to include an analysis of the state of the art and market landscape, aligning research activities with identified needs and presenting a range of technical alternatives to address the challenge. Furthermore, to stimulate dialogue with the supply side, public procurers are required to organise proposals that should demonstrate sustainability of the action beyond the life of the project.

The proposals should build on the outcomes of CSA projects funded under previous Horizon Europe work programmes aimed at creating Stronger grounds for pre-commercial procurement of innovative security technologies. The proposals should provide clear evidence to justify and de-risk the PCP action, demonstrating that the identified challenge is significant and necessitates a PCP action to mature certain technologies and compare alternatives. It should be shown that a consolidated group of practitioners and procurers with shared needs and requirements is committed to the PCP process, enabling informed decisions on future joint procurement of innovative solutions. Activities covered should include cooperation with policymakers to reinforce the national policy frameworks and mobilise substantial additional national budgets for PCP and innovation procurement in general beyond the scope of the project. The tender process to be followed is described in Annex H.

Proposals should demonstrate commitment to exploiting project results beyond its conclusion, ensuring engagement with stakeholders and implementation of strategies for future uptake. Applicants should also clarify measures to ensure compliance with the principles of the EU Directive on public procurement, particularly those related to PCP. The required open market consultations should be completed in at least three EU Member States. Prior consultations conducted under previous CSA projects should be used, provided they ensured procurement viability and remain relevant to the current state of the art.

Involvement of procurement decision makers is recommendable to ensure that end solution(s) are adopted by public buyers, increasing the societal impact of the related research activities. Therefore, procurers should declare in the proposal their interest to pursue deployment of solutions resulting from the PCP in case the PCP delivers successful solutions and indicate whether they will:

1.Procure successful solution(s) as part of the PCP.

2.Launch a separate follow-up procurement after the PCP to buy such type of solutions.

3.Adopt successful solutions without the need to procure them (e.g. in case of open-source solutions).

4.Foresee financial or regulatory incentives for others to adopt successful solutions (e.g. in case the final end-users of the solutions are not the procurers but for example citizens).

In these four cases, the procurers can implement the project as a fast-track PCP 165 . In the first case, the procurers should foresee the budget in the proposal to purchase at least one solution during the PCP. In the second case, the procurers should include in the proposal a deliverable that prepares the follow-up procurement to purchase such type of solution(s) after the PCP. In the first and third case, the procurers should foresee sufficient time during the project to deploy and validate that the solutions function well after installation. In the fourth case, the procurers can use financial support to third parties to provide financial incentives to final end-users that are not part of the consortium (e.g. citizens) to adopt the solutions, including costly hardware components, with a maximum budget of EUR 100.000.

Applicants should propose an implementation of the project that includes:

1.A minimal preparation stage dedicated to finalising the tendering documents package for a PCP call for tenders based on the technical input, and to define clear verification and validation procedures, methods and tools for the evaluation of the prototypes to be developed throughout the PCP phases.

2.Moreover, to ensure the sustainability and uptake of the developed solutions, proposals should outline clear plans for post-PCP activities. As outlined in the general annexes of the Horizon Europe Work Programme 2026-2027, the topic allows public buyers to use the fast-track PCP option (e.g. 2 instead of 3 phases) when they commit to buying or deploying the resulting solutions after the PCP. However, if such a commitment is not yet in place at the proposal stage, the call expects proposers to include a deliverable outlining concrete activities to prepare the ground for follow-up deployment or procurement after the PCP.

3.Launching the call for tenders for research and development services. The call for tenders should envisage a competitive development composed of different phases that would lead to at least 2 prototypes from 2 different providers to be validated in real operational environment at the end of the PCP cycle;

4.Conducting the competitive development of the prototypes following the PCP principles including a design phase, an integration and technical verification phase and a validation in real operational environment phase. In evaluating the proposals and the results of the PCP phases, the applicants should consider technical merit, feasibility and commercial potential of proposed research efforts.

5.Consolidating the results of the evaluation of the developed prototypes, extracting conclusions and recommendations from the validation process, and defining a strategy for a potential uptake of solutions inspired in the PCP outcomes, including a complete technical specification of the envisaged solutions and standardisation needs and/or proposals. This strategy should consider joint-cross border procurement schemes and exploit synergies with other EU and national non-research funds.

Applicants are expected to maximise the visibility of the project outcomes to the wide community of potential EU public buyers. Liaison with other civil security communities beyond those addressed by the project is encouraged in order to assess the possible reuse and extensibility of the identified solutions to different domains.

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Strengthened Security Research and Innovation Destination.

HORIZON-CL3-2026-01-SSRI-03: Public procurement of innovation for security

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 2.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.00 million.

Type of Action

Public Procurement of Innovative Solutions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the participation 166 , as beneficiaries, of at least 3 practitioners and 3 public procurers. These beneficiaries must be from at least 3 different EU Member States or Associated Countries. One organisation can have the role of practitioner and public procurer simultaneously, both counting for the overall number of organisations required for eligibility. Among the public procurers 167 , minimum two must be independent legal entities that are public procurers, each established in a different Member State or Associated Country and with at least one of them established in a Member State.

For participants with practitioner status, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

PCP/PPI procurement costs are eligible.

The specific conditions for actions with PCP/PPI procurements in section H of the General Annexes apply to grants funded under this topic.

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Last mile support to previous pre-commercial procurement (PCP) actions;

2.Development and deployment of innovative security solutions to address emerging threats, including post-quantum cryptography to counter emerging quantum threats, improving the effectiveness and efficiency of public security services;

3.Implementation of pilot projects and real-world testing, ensuring scalability and contributing to innovative security technologies.

Scope: This Public Procurement of Innovative Solutions (PPI) initiative aims to advance the adoption of innovative civil security solutions. The focus is on solutions that have been partially demonstrated on a small scale and are nearly or already available in small quantities but have not yet been widely adopted or produced at scale. These solutions should demonstrate a clear market potential and be new to the procurers, their market segment, or the internal EU market, and must be relevant to procurers across EU Member States and/or Associated Countries.

This PPI will specifically target innovative solutions that can address critical challenges in civil security and that are aligned with market readiness criteria. The solutions should meet requirements for sustainability (both operational and environmental), interoperability, adaptability, and be commercially viable while still holding residual market risks, such as not yet being produced in large quantities or at market-ready quality and pricing.

This initiative will focus on solutions that have already demonstrated partially successful results but require scaling, refinement, or deployment in new environments to meet mass-market price/quality standards. This is in line with Horizon Europe’s objective of fostering the early adoption of innovations that are critical to improving civil security across Europe 168 .

In compliance with the requirements of the Horizon Europe Work Programme – General Annex H, this action will engage in open market consultations with potential tenderers and end-users to identify gaps between perceived procurement needs and current industry developments. Feedback from these consultations will inform the PPI tender specifications, ensuring that the PPI emphasizes the early adoption of innovative solutions rather than the procurement of fully mature or mass-market technologies. The market readiness of the solutions can be verified through conformity testing, certification, or quality labelling. The work will also involve establishing evaluation criteria based on best-value-for-money rather than solely on the lowest price, ensuring that innovations are assessed for both their technical performance and their potential to deliver long-term value.

The PPI contract notices will be published EU-wide, with offers evaluated on objective criteria, ensuring transparency and fairness in the selection process. Functional/performance-based specifications will be used to define the challenges and problems to be solved, rather than prescriptive solutions, and procurement will avoid any conflicts of interest. The distribution of Intellectual Property Rights (IPR) will be clearly outlined in the PPI call for tenders, in line with the objective of promoting fair and wide exploitation of the results.

The process to be followed for the preparation and publication of the open market consultation and call for tender is described in General Annex H.

By fostering the early adoption of innovative technologies, this PPI initiative will enable the European civil security sector to address emerging threats, while contributing to the EU’s broader goals of technological sovereignty and market innovation. This will allow public authorities to remain at the forefront of addressing evolving risks and threats. The action will also catalyse innovation, drive competition, and significantly reduce the time needed to move from the initial concept to market.

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Strengthened Security Research and Innovation Destination.

HORIZON-CL3-2026-01-SSRI-04: Development of ecosystem and next-generation capabilities for a secured European Critical Communication System in civil security

Call: Civil Security for Society 2026

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

The following additional eligibility criteria apply:

This topic requires the active involvement, as beneficiaries, of at least 3 first responders’ organisations. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 169 .

Security Sensitive Topics

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Creation of an integrated ecosystem for secure and resilient communication systems to support civil security operations across Europe;

2.Advancement of next-generation capabilities, ensuring robust, scalable, and interoperable communication systems for critical civil security functions relevant for the future EU Critical Communication System (EUCCS).

Scope: The European Union Critical Communication System (EUCCS) is a flagship initiative aiming at gradual development of a unified, secure, and interoperable communication infrastructure to support critical public safety and civil security operations across Europe. Aims to provide law enforcement, first responders, emergency services, and other critical sectors with reliable, real-time communication capabilities, even in challenging or high-risk environments. This topic aims to streamline the creation of an integrated ecosystem for secure and resilient communication systems that support civil security operations across Europe. It aims to advance next-generation capabilities, ensuring robust, scalable, and interoperable communication systems tailored to the critical civil security functions that will be required for the future EUCCS, taking into consideration the ongoing migration of the EU towards post-quantum cryptography.

The action funded under this topic will develop secure communication devices and applications that meet the unique needs of practitioners across various disciplines. These solutions will go beyond current technologies, enabling specialized, ruggedized devices that support hands-free capabilities, including wearable sensors, haptics, and augmented reality to enhance situational awareness. Devices will be designed to ensure communication in environments lacking cellular infrastructure and will be built with high standards of security, including addressing cryptographic security via post-quantum cryptography, and trustworthiness while also ensuring an inclusive and gender-sensitive approach to meet the diverse needs of all users. The action funded under this topic should support relevant standardisation processes where possible.

The solutions should be mission-critical, offering high availability, resilience, data exchange and authentication both secured via state-of-the-art post-quantum cryptographic protocols, even in areas with limited or no commercial network coverage. They must be fully compatible with the EUCCS, leveraging 3GPP Mission Critical Services (MCX) and open APIs to create a versatile and interoperable ecosystem. By working closely with first responders and utilizing open platforms, the project will ensure that the developed solutions address the specific operational needs of responders, facilitating effective cross-agency and pan-European collaboration.

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Strengthened Security Research and Innovation Destination.

HORIZON-CL3-2027-01-SSRI-01: Accelerating uptake through open proposals for advanced SME innovation

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 4.50 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

The following additional eligibility conditions apply:

Consortia must include, as beneficiaries:

- A minimum of three (3) to a maximum of seven (7) partners.

- At least 2 SMEs 170 from 2 different Member States.

- At least 1 end-user organisation in the areas addressed by the proposal, namely one of the following options:

1.Option A "Fighting Organised Crime and Terrorism’’

2.Option B ‘"Disaster-Resilient Society’’

3.Option C "Resilient Infrastructure’’ and

4.Option D ‘"Border Management’’.

Participation of non-SME industries and Research and Technology Organisations (RTOs) is not excluded, but it must be limited to 15% of the proposed budget.

At least 50% of the proposed budget must be allocated to SMEs.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

Eligible proposals submitted under this topic and exceeding all the evaluation thresholds will be awarded a STEP Seal [ https://strategic-technologies.europa.eu/about/step-seal_en ].

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 171 .

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Development of a mature technological solution addressing EU security policy priorities in the areas addressed by the Cluster 3 work programme and in particular the destination of fighting crime and terrorism, disaster resilient societies, border management and resilient infrastructure;

2.Facilitate increased and sustained collaboration between small and medium-sized enterprises (SMEs), public research partners, and academia, leading to improved knowledge transfer within the European innovative SME ecosystem;

3.Mitigate difficulties in access to finance and new international markets, thereby enhancing the growth and expansion of European innovative SMEs.

Scope: Europe’s 25 million small and medium enterprises (SMEs) are the backbone of the EU economy. SMEs can bring innovation to societal challenges, including the security of EU citizens. Innovative SMEs and high-tech start-ups can transform and modernise EU security capabilities.

However, despite the innovation capacity of EU SMEs, these often experience difficulties in finding their way to the public markets. These include red tape in public contracts, access to new customers, access to finance, industrial competition and Intellectual Property (IP) valorisation. These difficulties are exacerbated in markets that show restrictions of different kind, as it is the case of security.

Knowing that SMEs require additional support to reach the security buyers and that the collaboration opportunities offered by the projects of the Pillar II of Horizon Europe can be a catalyst for uptake, this topic aims to offer a collaborative environment for small and medium innovators to tailor their innovations to the specific needs of civil security end-users, taking into account the urge to address the diverse needs of all citizens, regardless of gender, age or ability.

Applicants are invited to submit proposals for technology development along with the following principles:

1.Focus on mature technological solutions addressing EU security policy priorities in the areas addressed by the Cluster 3 Work Programme;

2.Fostering collaboration between SMEs from different Member States and Associated Countries;

3.Involving security end-users in the role of validator and potential first-adopter of the proposed innovations;

4.Fostering collaboration schemes between small companies and research and technology organisations and/or big industrial players aimed at fostering innovative technology transfer or creating innovative business models that facilitate access to market and strengthen the innovation capacity of EU SMEs and start-ups in the domain of civil security.

Examples of activities to plan in the proposed projects include, but are not limited to: assimilating market requirements; facilitating access to additional funding; approaching potential public buyers; assess competitive landscape; supporting in innovation management (methodological and process innovation, business model innovation, market innovation); assist in IP management and exploitation; provide guidance for expansion to future markets, etc.

The participation of research and technology organisations should not focus on own technology development but on supporting the small industrial players in accelerating the technology transfer of innovative security solutions for their further development and production.

It is encouraged that one SME takes the coordinator role 172 . If the coordinator is not an SME, this should be duly justified.

The projects should have a maximum estimated duration of 2 years.

Under this topic, projects should address one of the following areas addressed by the Cluster 3 work programme: Fighting Crime and Terrorism (FCT, Option A), Disaster-Resilient Society (DRS, Option B), Resilient Infrastructure (INFRA, Option C), Border Management (BM, Option D).

Some (indicative and non-exhaustive) examples of domains that could be addressed under the FCT area are: mobile forensics; deepfake detection; detection of counterfeiting (fake items, fake currency bills) or falsified/forged documents (passports, ID cards); detection and countering of advanced forms of malware, as well as non-cash payment frauds and other cyber-scams.

Some (indicative and non-exhaustive) examples of domains that could be addressed under the DRS area are: data and satellite/remote sensing information exploitation, positioning and localisation tracking and tracing, monitoring and surveillance for disaster prevention.

Some (indicative and non-exhaustive) examples of domains that could be addressed under the INFRA area are: physical access control, autonomous systems used for infrastructure protection, positioning and localisation tracking and tracing, monitoring and surveillance of environments and activities.

Some (indicative and non-exhaustive) examples of domains that could be addressed under the BM area are: facilitated border checks; secure documents and identity management for border crossings; border surveillance; detection of drugs, explosives, Chemical, Biological, Radiological and Nuclear (CBRN), weapons and/or other dangerous materials in customs environment; detection of stolen, smuggled, illicit or illegal goods (cigarettes, art, cultural goods, wildlife) in a customs environment.

Where relevant, proposals are invited to consider legal aspects to support the operationalization, policy integration, and institutional transformation of security solutions. This might include, for instance, the design of legal, policy, and/or standardization pathways to support the operational uptake of security solutions.

This topic contributes to the Strategic Technologies for Europe Platform (STEP 173 ) and addresses civil security technologies falling under the sectors of “Digital technologies and deep-tech innovation” 174 . This topic contributes to the objectives stated in the STEP Regulation, e.g., to support the European industry and boost investment in critical technologies in Europe, and, to contribute to reducing or preventing the strategic dependencies of the Union.

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Strengthened Security Research and Innovation Destination.

HORIZON-CL3-2027-01-SSRI-02: Open grounds for future pre-commercial procurement of innovative security technologies

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility conditions apply:

This topic requires the participation, as beneficiaries, of at least 6 end-user organisations as well as at least 3 public procurers. One beneficiary can have the role of end-user and public procurer simultaneously, both counting towards the number of such entities required for the additional eligibility condition. These beneficiaries must be from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

Open market consultations carried out during this project must take place in at least 3 EU Member States or Associated Countries.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 175 .

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.Establish a consolidated group of potential buyers with shared needs and requirements, committed to carrying out a pre-commercial procurement (PCP) action for future joint procurement of innovative solutions;

2.Evidence for Future PCP Action: Provide clear evidence justifying the necessity of a PCP action to complete the maturation cycle of certain technologies and compare different alternatives;

3.Increased capacity of EU public procurers to align requirements with industry and future products and to attract innovation and innovators from security and other sectors through common validation strategies, rapid innovation, experimentation and pre-commercial procurement.

Scope: End-users and public procurers from several countries are invited to submit proposals for a preparatory action that should build the grounds for a future pre-commercial procurement (PCP) action. Both this preparatory action and the future PCP action are open to proposals oriented to the acquisition of research and development (R&D) services for the development of innovative technologies, systems, tools or techniques under the priorities laid down in this Work Programme.

In preparing the grounds for a possible future PCP action, the outputs of this Coordination and Support Action (CSA) should take into consideration:

1.The policy priorities described in this Work Programme Part for the security areas mentioned above;

2.The EU Directive for public procurement and in particular with the provisions related to PCP;

3.The specific provisions and funding rates of PCP actions and the specific requirements for innovation procurement (PCP/PPI) supported by Horizon Europe grants, as stated in the General Annex H of the Horizon Europe Work Programme;

4.The guidance for attracting innovators and innovation, as explained in the European Commission Guidance on Innovation Procurement C(2021) 4320, in particular those measures oriented to reduce the barriers to high-tech start-ups and innovative SMEs.

During the course of the project, the applicants are expected to deliver clear evidence on a number of aspects in order to justify and de-risk a possible follow-up PCP action, including:

1.That the challenge is pertinent and that indeed a PCP action is required to complete the maturation cycle of certain technologies and to compare different alternatives;

2.That there is a consolidated group of potential buyers with common needs and requirements which are committed to carry out a PCP action in order to be able to take an informed decision on a future joint procurement of innovative solutions;

3.That there is a quantifiable and identifiable community of potential buyers (including and beyond those proposed as beneficiaries in the proposal) who would share to a wide extent the common needs and requirements defined and who could be interested in exploring further joint-uptake of solutions similar to those developed under the PCP, should these prove to be technologically mature and operationally relevant by the end of the project;

4.That the state of the art and the market (including research) has been explored and mapped, and that there are different technical alternatives to address the proposed challenge;

5.That a future PCP tendering process is clear, that a draft planning has been proposed and that the supporting documentation and administrative procedures will be ready on due time in order to launch the call for the acquisition of R&D services according to the PCP rules;

6.That the technology developments to be conducted in the future PCP can be done in compliance with European societal values, fundamental rights and applicable legislation, including in the area of free movement of persons, privacy and protection of personal data;

7.That in developing technology solutions, societal and gender aspects (e.g., perception of security, possible side effects of technological solutions, societal resilience) are taken into account in a comprehensive and thorough manner.

If the applicants intend to submit a proposal for a follow-up PCP in a future Horizon Europe Cluster 3 Work Programme, they should ensure that the above evidence is consolidated in the project deliverables of this CSA before the submission of the PCP proposal.

The project should have a maximum estimated duration of 1 year.

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Strengthened Security Research and Innovation Destination.

HORIZON-CL3-2027-01-SSRI-03: Demand-led innovation in security

Call: Civil Security for Society 2027

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 5.83 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.83 million.

Type of Action

Pre-commercial Procurement

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

The following additional eligibility conditions apply:

This topic requires the participation 176 , as beneficiaries, of at least 3 practitioners and 3 public procurers. These beneficiaries must be from at least 3 different EU Member States or Associated Countries. One organisation can have the role of practitioner and public procurer simultaneously, both counting for the overall number of organisations required for eligibility. Among the public procurers 177 , minimum two must be independent legal entities that are public procurers, each established in a different Member State or Associated Country and with at least one of them established in a Member State.

For participants with practitioner status, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants / prizes. The maximum amount to be granted to each third party is EUR 100 000 to provide financial incentives to final end-users that are not part of the consortium (e.g., citizens) to adopt the solutions, including costly hardware components.

PCP/PPI procurement costs are eligible.

The specific conditions for actions with PCP/PPI procurements in section H of the General Annexes apply to grants funded under this topic.

Beneficiaries must ensure that the subcontracted work is performed in at least 3 Member States — unless otherwise approved by the granting authority.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes:

1.A community of EU civil security practitioners with common user/functional needs for innovative technology solutions is identified, supported by an industrial base, in particular SMEs and Startups, to access the public procurement market and scale up their business;

2.Procurers facilitate the commercialisation of the innovative solutions developed by their successful suppliers by providing them with first customer references for the validation and first pilot deployment;

3.Tested and validated capacity of EU technology and industrial base to develop and produce technology prototypes that are accessible and meet the diverse needs of the EU user community, regardless of their gender, age and ability;

4.Improved delineation of the EU market (including demand and supply) for innovative civil security systems that can articulate alternative options for uptake in function of different industrialisation needs, commercialisation needs, acquisition needs, deployment needs and additional funding needs (beyond R&I funding).

Scope: As past experience shows that pre-commercial procurement opens up the procurement market for startups and enables the public sector to address societal challenges more effectively, public procurers should make more strategic use of PCP. Applicants are invited to submit proposals for PCP action to acquire Research and Development (R&D) services and innovative civil security technology solutions.

Proposals should demonstrate interest from a broader community of potential buyers, beyond the direct beneficiaries, who share similar needs and are open to jointly adopting the solutions developed, provided they are proven mature and operationally viable. The proposals are expected to include an analysis of the state of the art and market landscape, aligning research activities with identified needs and presenting a range of technical alternatives to address the challenge. Furthermore, to stimulate dialogue with the supply side, public procurers are required to organise proposals that should demonstrate sustainability of the action beyond the life of the project.

The proposals should build on the outcomes of CSA projects funded under previous Horizon Europe work programmes aimed at creating Stronger grounds for pre-commercial procurement of innovative security technologies. The proposals should provide clear evidence to justify and de-risk the PCP action, demonstrating that the identified challenge is significant and necessitates a PCP action to mature certain technologies and compare alternatives. It should be shown that a consolidated group of practitioners and procurers with shared needs and requirements is committed to the PCP process, enabling informed decisions on future joint procurement of innovative solutions. Activities covered should include cooperation with policymakers to reinforce the national policy frameworks and mobilise substantial additional national budgets for PCP and innovation procurement in general beyond the scope of the project. The tender process to be followed is described in Annex H.

Proposals should demonstrate commitment to exploiting project results beyond its conclusion, ensuring engagement with stakeholders and implementation of strategies for future uptake. Applicants should also clarify measures to ensure compliance with the principles of the EU Directive on public procurement, particularly those related to PCP. The required open market consultations should be completed in at least three EU Member States. Prior consultations conducted under previous CSA projects should be used, provided they ensured procurement viability and remain relevant to the current state of the art.

Involvement of procurement decision makers is recommendable to ensure that end solution(s) are adopted by public buyers, increasing the societal impact of the related research activities. Therefore, procurers should declare in the proposal their interest to pursue deployment of solutions resulting from the PCP in case the PCP delivers successful solutions and indicate whether they will:

1.Procure successful solution(s) as part of the PCP.

2.Launch a separate follow-up procurement after the PCP to buy such type of solutions.

3.Adopt successful solutions without the need to procure them (e.g. in case of open-source solutions).

4.Foresee financial or regulatory incentives for others to adopt successful solutions (e.g. in case the final end-users of the solutions are not the procurers but for example citizens).

In these four cases, the procurers can implement the project as a fast-track PCP 178 . In the first case, the procurers should foresee the budget in the proposal to purchase at least one solution during the PCP. In the second case, the procurers should include in the proposal a deliverable that prepares the follow-up procurement to purchase such type of solution(s) after the PCP. In the first and third case, the procurers should foresee sufficient time during the project to deploy and validate that the solutions function well after installation. In the fourth case, the procurers can use financial support to third parties to provide financial incentives to final end-users that are not part of the consortium (e.g. citizens) to adopt the solutions, including costly hardware components, with a maximum budget of EUR 100.000.

Applicants should propose an implementation of the project that includes:

1.A minimal preparation stage dedicated to finalising the tendering documents package for a PCP call for tenders based on the technical input, and to define clear verification and validation procedures, methods and tools for the evaluation of the prototypes to be developed throughout the PCP phases.

2.Moreover, to ensure the sustainability and uptake of the developed solutions, proposals should outline clear plans for post-PCP activities. As outlined in the general annexes of the Horizon Europe Work Programme 2026-2027, the topic allows public buyers to use the fast-track PCP option (e.g. 2 instead of 3 phases) when they commit to buying or deploying the resulting solutions after the PCP. However, if such a commitment is not yet in place at the proposal stage, the call expects proposers to include a deliverable outlining concrete activities to prepare the ground for follow-up deployment or procurement after the PCP.

3.Launching the call for tenders for research and development services. The call for tenders should envisage a competitive development composed of different phases that would lead to at least 2 prototypes from 2 different providers to be validated in real operational environment at the end of the PCP cycle;

4.Conducting the competitive development of the prototypes following the PCP principles including a design phase, an integration and technical verification phase and a validation in real operational environment phase. In evaluating the proposals and the results of the PCP phases, the applicants should consider technical merit, feasibility and commercial potential of proposed research efforts.

5.Consolidating the results of the evaluation of the developed prototypes, extracting conclusions and recommendations from the validation process, and defining a strategy for a potential uptake of solutions inspired in the PCP outcomes, including a complete technical specification of the envisaged solutions and standardisation needs and/or proposals. This strategy should consider joint-cross border procurement schemes and exploit synergies with other EU and national non-research funds.

Applicants are expected to maximise the visibility of the project outcomes to the wide community of potential EU public buyers. Liaison with other civil security communities beyond those addressed by the project is encouraged in order to assess the possible reuse and extensibility of the identified solutions to different domains.

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Strengthened Security Research and Innovation Destination.

Other actions not subject to calls for proposals

1. External expertise for reviews of projects

This action will support the use of appointed independent experts for the monitoring of actions (grant agreement, grant decision, public procurement actions, financial instruments) funded under Horizon Europe and previous Framework Programmes for Research and Innovation, and where appropriate include ethics checks, as well as compliance checks regarding the Gender Equality Plan eligibility criterion 179 .

Form of Funding: Other budget implementation instruments

Type of Action: Expert contract action

Indicative timetable: 1st quarter 2026 and 1st quarter of 2027

Indicative budget: EUR 0.80 million from the 2026 budget and EUR 0.80 million from the 2027 budget

2. Workshops, conferences, experts, communication activities, studies and innovation uptake promotion

1.Organisation of the annual Security Research Event.

2.Support to workshops, expert groups, communications activities, or studies. Workshops are planned to be organised on various topics to involve end-users (e.g. the Community for European Research and Innovation for Security); preparation of information and communication materials, etc.

3.Organisation of cybersecurity conferences and support to other cybersecurity events; socio-economic studies, impact analysis studies and studies to support the monitoring, evaluation and strategy definition for cybersecurity and digital privacy policy.

4.Support to promotion of innovation uptake, including through supporting developing certification testing methodologies for innovative technologies.

5.Needs analysis and options for enabling the sharing of security research projects outputs (tools).

Form of Funding: Procurement

Type of Action: Public procurement

Indicative timetable: 1st quarter 2026 and 1st quarter of 2027

Indicative budget: EUR 2.13 million from the 2026 budget and EUR 1.52 million from the 2027 budget

3. Indirectly Managed Action by the ECCC (2026)

The Commission intends to conclude a contribution agreement with the European Cybersecurity Competence Centre (ECCC) for the implementation of Horizon Europe cybersecurity actions not co-funded by Member States, in accordance with Article 5(5) of Regulation (EU) 2021/8878. In particular, the contribution agreement will entrust the ECCC with the implementation of a call for proposals according to the specifications in the Appendix set out below. Further to the contribution agreement, the ECCC will launch a call for proposals in accordance with the specifications in the Appendix set out below. These include topics where participation will be limited in accordance with Article 22(5) of the Horizon Europe Regulation to legal entities established in Member States and Horizon Europe Associated Countries (eligible countries). In addition, for such topics, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, will not be eligible to participate.

Legal entities:

European Cybersecurity Competence Centre (ECCC), Polytechnic University of Bucharest, Strada Splaiul Independentei Nr.313, Sector 6, Bucharest 060042, Romania

Form of Funding: Indirectly managed actions

Type of Action: Indirectly managed action

Indicative budget: EUR 56.20 million from the 2026 budget

APPENDIX – Indirectly managed action by the ECCC 2026

Specifications of the ‘Cybersecurity’ call to be launched by ECCC

Call - Cybersecurity

HORIZON-CL3-2026-02-CS-ECCC

Conditions of the call 180

Proposals are invited against the following topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 181

Indicative number of projects expected to be funded

2026

Opening: 3 March 2026

Deadline(s): 15 September 2026

HORIZON-CL3-2026-02-CS-ECCC-01:Approaches and tools for security in software and hardware development and assessment

RIA

20

3-4

4-5

HORIZON-CL3-2026-02-CS-ECCC-02:Enhancing the Security, Privacy and Robustness of AI Models and Systems (SecureAI)

IA

21.2

3-4

4-5

HORIZON-CL3-2026-02-CS-ECCC-03:Advanced cryptographic schemes and High-Assurance high-speed cryptographic implementations

RIA

15

2-3

3-4

Overall indicative budget

56.2

HORIZON-CL3-2026-02-CS-ECCC-01: Approaches and tools for security in software and hardware development and assessment

Specific Conditions

Expected EU Contribution per Project:

The Commission estimates that an EU contribution of between EUR 3 and 4 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative Budget:

The total indicative budget for the topic is 20 million.

Type of Action:

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, participation in this topic is limited to legal entities established in Member States and Associated Countries. In order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, shall not participate in the action.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering a broad range of research areas, grants will be awarded to applications not only in order of ranking but at least also to the two highest ranked proposal addressing expected outcome a) and the highest ranked proposal addressing expected outcome b), provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 182 .

Security Sensitive Topics:

Some activities resulting from this topic may involve using classified background and/or producing security-sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome:

Proposals are expected to contribute to one or more of the following:

1.Enhanced security frameworks for both hardware and software supply chains, building on root-of-trust architectures and secure lifecycle management;

2.Secure and trusted chip architectures for next-generation computing and networking systems;

3.Integrated security-by-design approaches in software development, aimed to be aligned with relevant regulatory requirements;

4.Security testing methodologies, including formal verification approaches and AI-driven security testing methodologies;

5.Standardised methodologies for hardware security assessment, also contributing to cybersecurity certification.

Scope:

The increasing complexity and globalisation of software and hardware supply chains introduce new vulnerabilities that cyber adversaries can exploit. Ensuring the security of both software and hardware components across the lifecycle of digital systems is paramount. This topic aims to develop innovative tools, methods, and processes to secure the entire ecosystem of software and hardware development.

Proposals should explicitly select one main area of focus but can also address both:

a. Secured hardware systems over trusted Chips

The security of modern computing infrastructures relies heavily on the robustness of hardware components. This subtopic aims to develop robust security solutions for trusted hardware platforms, focusing on secured microprocessors, secure boot mechanisms, and cryptographic acceleration. Proposals are also expected to address the risks of hardware-based vulnerabilities and backdoors, ensuring the security of devices from edge to cloud, also taking into account emerging threats, including quantum where relevant. Synergies with existing EU initiatives on trusted hardware (e.g., CHIPS JU, EuroHPC) are encouraged. The topic is expected to:

1.Develop new architectures for tamper-resistant chips and processors. Exploring novel designs for secure microprocessors, leveraging hardware-level security enhancements, and integrating cryptographic co-processors that may also support post-quantum cryptography (PQC), for enhanced protection against tampering and side-channel attacks.

2.Enhance supply chain transparency for chip production and integration. Exploring innovative ways to improve traceability and accountability in chip manufacturing processes, including methods such as post-quantum secure hardware roots of trust, blockchain for tracking components, or certification mechanisms.

3.Establish security-by-design methodologies for hardware security assessment. Advancing methodologies for systematic security testing of hardware components, including automated vulnerability analysis, verification frameworks, and integration of security assessment into chip design and lifecycle management.

4.Develop methods and tools for an effective and efficient non-destructive authentication and physical analysis of integrated circuits and multi-chips modules (chiplets).

5.Develop technical means for ensuring hardware supply chain security, and secure PQC implementations: hardware trojan and backdoor detection, hardware watermarking, relevant reverse engineering techniques, countermeasures also against new classes of hardware physical attacks. Develop self-healing firmware able to recover from cyber-attacks. Develop firmware able to leverage advanced anomaly detection, AI-driven threat mitigation and secure rollback mechanisms to automatically identify cyber-attacks, isolate compromised components restore the system to a trusted state while maintaining operational continuity.

b. Software Supply Chain security

The integrity of software supply chains is critical to mitigating cybersecurity threats such as supply chain attacks, dependency vulnerabilities, and compromised software components. This subtopic focuses on mitigating security risks in software supply chains, including secure code provenance, automated vulnerability detection, and secure software development lifecycle (SDLC) methodologies and tools, including those related to PQC security. Proposals should integrate formal verification approaches or AI-assisted security testing, leveraging upcoming European and International standards for supply chain security. The topic is expected to:

1.Develop innovative tools for real-time software vulnerability detection and automatic patching. Advancing the state of automated detection techniques, incorporating dynamic analysis, AI-driven pattern recognition, predictive analytics to proactively identify security weaknesses before exploitation and self-healing mechanisms.

2.Enhance secure software frameworks, including protection against the quantum threat. Exploring new methodologies for integrating security-by-design principles across development workflows, incorporating approaches such as automated security policy enforcement, modular security components, and improved dependency management.

3.Improve resilience against supply chain cyber threats. Investigating novel mitigation strategies, including provenance tracking for software components and their analysis, secure update distribution mechanisms including protection from emerging quantum threats where relevant, enhanced anomaly detection, and multi-layer defence approaches to ensure integrity and trustworthiness.

HORIZON-CL3-2026-02-CS-ECCC-02: Enhancing the Security, Privacy and Robustness of AI Models and Systems (SecureAI)

Specific Conditions

Expected EU Contribution per Project:

The Commission estimates that an EU contribution of between EUR 3 and 4 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative Budget:

The total indicative budget for the topic is EUR 21.2 million.

Type of Action:

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, participation in this topic is limited to legal entities established in Member States and Associated Countries. In order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, shall not participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 183 .

Security Sensitive Topics:

Some activities resulting from this topic may involve using classified background and/or producing security-sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome:

Proposals are expected to contribute to one or more of the following:

1.Robust AI models and systems capable of resisting different classes of adversarial manipulation;

2.Innovative defence mechanisms for AI models and systems against new attack families;

3.Methodologies for detecting and mitigating attacks, such as data poisoning, backdoor exploitation and misclassification;

4.AI systems leveraging privacy-enhancing technologies that maintain data confidentiality and regulatory compliance, enabling trusted in-house AI deployments (e.g., for governments and enterprises).

Scope:

The increasing reliance on AI in cybersecurity, critical infrastructure, and decision-making processes raises concerns about the security and robustness of AI systems. As AI systems become more prevalent, they are increasingly targeted by adversarial attacks that manipulate inputs, compromise training data, or introduce hidden vulnerabilities. This topic aims to strengthen the resilience of AI systems and algorithms against various threats and attacks, such as enhancing their resilience against adversarial attacks, backdoor injections, and data poisoning. Proposals should develop real-time anomaly detection, mitigation techniques to defend against adversarial attacks and robust federated learning techniques, in synergies with leading efforts on AI transparency, and in compliance with the AI Act. The topic is expected to:

1.Develop robust AI models resistant to adversarial attacks. Exploring techniques to harden AI models and systems against adversarial perturbations, such as adversarial training, robust optimisation, and defence mechanisms that enhance the trustworthiness of AI.

2.Improve detection of manipulated or poisoned training data. Advancing methodologies to identify and mitigate compromised datasets, leveraging techniques such as anomaly detection, provenance tracking, and automated data validation mechanisms.

3.Address the concept of Private AI by developing mechanisms that enable AI models to be trained, deployed and operated in privacy-preserving environments, particularly for sensitive use cases, as for example for government and enterprise settings. This includes ensuring AI computations and data remain within trusted execution boundaries (e.g. on-premise or regulated cloud environments), and leveraging existing and emerging privacy-enhancing techniques such as federated learning, secure aggregation, computing on encrypted data, quantum-safe homomorphic encryption and secure inference in deep learning to safeguard the protection of personal and other sensitive data throughout the AI lifecycle.

HORIZON-CL3-2026-02-CS-ECCC-03: Advanced cryptographic schemes and High-Assurance high-speed cryptographic implementations

Specific Conditions

Expected EU Contribution per Project:

The Commission estimates that an EU contribution of between EUR 2 and 3 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative Budget:

The total indicative budget for the topic is EUR 15 million.

Type of Action:

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, participation in this topic is limited to legal entities established in Member States and Associated Countries. In order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, shall not participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 184 .

Security Sensitive Topics:

Some activities resulting from this topic may involve using classified background and/or producing security-sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome:

Proposals are expected to contribute to one or more of the following:

1.Quantum-resistant cryptographic primitives, also other than lattice-based approaches if relevant, that enhance the security and privacy of digital wallets, both for natural persons and wallets, as well as the design and implementation of post-quantum solutions for entity authentication and authenticated key establishment over insecure networks;

2.Formal verification tools, improved High-Assurance Cryptographic Software (HACS) approaches and their integration in software workflows, to provide strong security guarantees in post-quantum migration, and enable streamlined evidence-based evaluation of secure systems that use cryptography.

Scope:

The development of new digital signatures and advanced cryptographic schemes, tailored specifically to the use cases and requirements in the context of wallets/eIDs, for privacy and business applications is highly relevant nowadays. Moreover, these devices need secure connections over insecure networks requiring protocols for entity authentication, authenticated key establishment, as well as Password Authenticated Key Exchange (PAKE) schemes for ensuring user authentication via passwords in different use cases and for data recovery protocols of Wallet data.

Another key area is the development of High-Assurance Cryptographic Software (HACS), including automated evaluation methods.

Considering the above, proposals should address one of the following technology areas:

1.Design and implementation of PQC advanced schemes and protocols for enhanced security and privacy, also including schemes other than lattice-based approaches if relevant. Proposals should also include recommendations that balance security, performance, and usability in practical applications and be based on open-source reusable software libraries.

2.Development of a unified specification language to formalise and document conditions on cryptographic safety and security in software implementations; development and improvement of tools and methodologies that can be used to evaluate both the implementation and the usage of cryptography in software applications and provide formal machine-checked guarantees of correctness and security. Proposals should also consider improving existing HACS tools and their integration in such software implementations.

4. Indirectly Managed Action by the ECCC (2027)

The Commission intends to conclude a contribution agreement with the European Cybersecurity Competence Centre (ECCC) for the implementation of Horizon Europe cybersecurity actions not co-funded by Member States, in accordance with Article 5(5) of Regulation (EU) 2021/8878. In particular, the contribution agreement will entrust the ECCC with the implementation of a call for proposals according to the specifications in the Appendix set out below. Further to the contribution agreement, the ECCC will launch a call for proposals in accordance with the specifications in the Appendix set out below. These include topics where participation will be limited in accordance with Article 22(5) of the Horizon Europe Regulation to legal entities established in Member States and Horizon Europe Associated Countries (eligible countries). In addition, for such topics, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, will not be eligible to participate.

Legal entities:

European Cybersecurity Competence Centre (ECCC), Polytechnic University of Bucharest, Strada Splaiul Independentei Nr.313, Sector 6, Bucharest 060042, Romania

Form of Funding: Indirectly managed actions

Type of Action: Indirectly managed action

Indicative budget: EUR 71.80 million from the 2027 budget

APPENDIX – Indirectly managed action by the ECCC 2027

Specifications of the ‘Cybersecurity’ call to be launched by ECCC

Call - Cybersecurity

HORIZON-CL3-2027-02-CS-ECCC

Conditions of the call 185

Proposals are invited against the following topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 186

Indicative number of projects expected to be funded

2027

Opening: 2 March 2027

Deadline(s): 15 September 2027

HORIZON-CL3-2027-02-CS-ECCC-01:Artificial Intelligence for Cybersecurity applications

RIA

24.8

4-5

5-6

HORIZON-CL3-2027-02-CS-ECCC-02: Secure Computing Continuum (IoT, Edge, Cloud, Data spaces)

IA

24

4-5

5-6

HORIZON-CL3-2027-02-CS-ECCC-03: Secure PQC implementations, Cryptanalysis and Post-quantum Digital Trust

RIA

19

3-4

4-5

HORIZON-CL3-2027-02-CS-ECCC-04: New primitives for functionalities of future hybrid quantum-classical and quantum networks

RIA

4

4

1-2

Overall indicative budget

71.8

HORIZON-CL3-2027-02-CS-ECCC-01: Artificial Intelligence for Cybersecurity applications

Specific Conditions

Expected EU Contribution per Project:

The Commission estimates that an EU contribution of between EUR 4 and 5 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative Budget:

The total indicative budget for the topic is EUR 24.8 million.

Type of Action:

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, participation in this topic is limited to legal entities established in Member States and Associated Countries. In order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, shall not participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 187 .

Security Sensitive Topics:

Some activities resulting from this topic may involve using classified background and/or producing security-sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome:

Proposals are expected to contribute to one or more of the following:

1.AI-driven solutions for real-time cyber threat detection;

2.Advanced adaptive AI systems that evolve with dynamic cybersecurity challenges;

3.Contribute to drastically reduce reaction time for the recovery of systems.

Scope:

Artificial Intelligence is increasingly utilised in cybersecurity for threat detection, incident response, and adaptive defence mechanisms. However, AI-driven systems themselves are susceptible to adversarial manipulation and bias. This topic aims to advance AI-based cybersecurity applications while ensuring that AI-driven solutions remain resilient, transparent, and compliant with regulatory frameworks such as the AI Act. In this context, the topic explores the role of all types of AI, including generative AI, in cybersecurity applications, including automated threat detection, adaptive cyber defence, and AI-driven cyber threat intelligence. Proposals should develop solutions for trustworthy AI in cybersecurity contexts including addressing adversarial AI risks, in compliance with the provisions of the AI Act. The topic is expected to:

1.Develop AI-driven solutions and tools for real-time cyber threat detection. Investigating novel machine learning techniques to detect anomalies, malicious activity, and AI-powered cyber threats in real time, improving situational awareness and response times.

2.Develop adaptive AI systems capable of evolving with dynamic cybersecurity challenges. Exploring AI techniques that continuously learn from new cyber threats, adapting to emerging attack patterns, while maintaining robustness and explainability.

3.Support the future enhancements of Security Operation Centres/Cyber Hubs. Developing AI-enhanced SOC frameworks that integrate predictive analytics, automation, and threat intelligence to strengthen proactive defence measures.

HORIZON-CL3-2027-02-CS-ECCC-02: Secure Computing Continuum (IoT, Edge, Cloud, Data spaces)

Specific Conditions

Expected EU Contribution per Project:

The Commission estimates that an EU contribution of between EUR 3 and 4 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative Budget:

The total indicative budget for the topic is EUR 24 million.

Type of Action:

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, participation in this topic is limited to legal entities established in Member States and Associated Countries. In order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, shall not participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 188 .

Security Sensitive Topics:

Some activities resulting from this topic may involve using classified background and/or producing security-sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome:

Proposals are expected to contribute to one or more of the following:

1.Enhanced resilience against distributed cyber threats and adversarial attacks targeting interconnected systems, while preserving data privacy in highly dynamic and heterogeneous environments;

2.Security solutions tailored to distributed computing systems including for example IoT and edge computing environments, integrating privacy-preserving mechanisms;

3.Improved interoperability of security measures and cross-layer security, including the compatibility of privacy-enhancing technologies across different layers of the computing continuum and data spaces, and across providers in the multi-provider edge cloud continuum.

Scope:

This topic aims to advance security across the entire computing continuum, spanning IoT devices, edge computing, cloud infrastructures, AI computing environments, and data spaces. Proposals should address critical challenges such as ensuring data integrity in highly distributed and dynamic environments, implementing robust zero-trust architectures to secure interconnected and heterogeneous systems, and enabling comprehensive protection for sensitive data and processes. Privacy should be considered a core element of these approaches, ensuring that data confidentiality is preserved throughout its lifecycle, in compliance with relevant data protection frameworks, such as GDPR. Solutions are expected to deliver tangible and measurable security improvements across all layers of the continuum, prioritizing scalability, interoperability, trustworthiness, security and resilience against emerging threats.

Proposals are expected to address one or more of the following:

1.Develop advanced security solutions for edge to cloud. For example, investigating lightweight cryptographic techniques, including in combination with or based on post-quantum cryptography, incorporated in zero-trust architectures, and decentralized security models to ensure end-to-end protection from edge to cloud, while maintaining privacy during data transmission and processing.

2.Enhance interoperability of security measures across different computing layers. Exploring security protocols, identity and access management solutions, and cross-domain authentication mechanisms to seamlessly integrate security controls across diverse computing ecosystems, including privacy-preserving protocols that enable the secure and compliant data exchange.

3.Develop portable, deployable PQC acceleration solutions through SW/HW secure co-design to secure user data and computing tasks across heterogeneous platforms and applications in all layers of the continuum.

4.Improve resilience against distributed cyber threats. Exploring anomaly detection, including AI-driven anomaly detection, intrusion prevention techniques, and automated response mechanisms to counter emerging threats targeting interconnected infrastructures and data spaces, while upholding privacy through techniques such as federated analysis, secure multi-party computation, Fully Homomorphic Encryption or other.

Proposals are encouraged to develop synergies with activities and projects in HE Cluster 4.

HORIZON-CL3-2027-02-CS-ECCC-03: Secure PQC implementations, Cryptanalysis and Post-quantum Digital Trust

Specific Conditions

Expected EU Contribution per Project:

The Commission estimates that an EU contribution of between EUR 3 and 4 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative Budget:

The total indicative budget for the topic is EUR 19 million.

Type of Action:

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, participation in this topic is limited to legal entities established in Member States and Associated Countries. In order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, shall not participate in the action.

Legal and financial set-up of the Grant Agreements

The procedure is described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 189 .

Security Sensitive Topics:

Some activities resulting from this topic may involve using classified background and/or producing security-sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected Outcome:

Proposals are expected to contribute one or more of the following:

1.Practical robust implementations of PQC schemes that can withstand implementation attacks including side-channel attacks, fault attacks and combined attacks, and design of automated tools for evaluating the security of PQC implementations. Comprehensive guidelines for implementing countermeasures against a wide range of attacks;

2.Advances in understanding the quantum hardness of mathematical problem classes; new quantum algorithms and improvements in quantum programming and implementation; security validation methods; design of post-quantum schemes with improved security against quantum and AI-based attacks;

3.Post-quantum schemes and protocols to support privacy-friendly applications and services, including the secure and private use of electronic identities. Design of new digital signatures, key encapsulation mechanisms, and other schemes or use of existing ones to build new verification protocols.

Scope:

Securing PQC algorithm implementations is vital to protect against implementation attacks, such as side channel attacks, fault attacks and combinations of these, which may be amplified by deep learning. Current countermeasures incur significant overhead, and new approaches are needed to balance security and performance. Formal verification tools and methodologies can help achieve this goal and provide machine-readable evidence. Furthermore, to boost confidence in PQC systems, their security should be assessed, including the potential impact of new quantum algorithms or new optimizations of existing ones, also combined with AI.

Another key research area is digital trust in the post-quantum era, which requires transforming various areas, such as secure identities, data protection, access to essential services, and applications such as backup recovery, browser extensions and others into trusted and reliable solutions, via new post-quantum schemes and advanced building blocks for privacy-enhancing protocols.

Proposals should address one of the following technology areas:

1.Development of solutions to prevent implementation attacks, balancing security, performance and cost; research in new attacks, including AI-powered ones, and/or combination of attacks, to inform secure design; creation of testing frameworks for automated security evaluations; improvement of formal verification methodologies.

2.Quantum hardness analysis, via the study of the impact of new quantum algorithms or improvement of existing quantum algorithm implementations as well as the impact of AI-supported quantum attacks; analysis of cryptanalysis results; design of new post-quantum schemes using the information of the advances achieved/ fine-tuning of parameters sets.

3.Design of quantum-resistant schemes and protocols supporting the field of privacy-friendly applications and services, including electronic identities, verification protocols and pseudonymous access options, protocols for attestation and anonymous attestation, for real world scenarios, via the design of new digital signature schemes and key encapsulation mechanisms, design of advanced cryptographic schemes, and usage of existing schemes in new protocols, for post-quantum digital identity and digital trust systems.

HORIZON-CL3-2027-02-CS-ECCC-04: New primitives and protocols for functionalities of future hybrid classical-hybrid and quantum networks

Specific Conditions

Expected EU Contribution per Project:

The Commission estimates that an EU contribution of 4 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative Budget:

The total indicative budget for the topic is EUR 4 million.

Type of Action:

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, participation in this topic is limited to legal entities established in Member States and Associated Countries. In order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, shall not participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 190 .

Security Sensitive Topics:

Some activities resulting from this topic may involve using classified background and/or producing security-sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Expected outcome:

Proposals are expected to contribute to one or more of the following:

1.New primitives beyond Quantum Key Distribution (QKD) for future hybrid classical-quantum and quantum networks either as quantum equivalents of classical primitives or as new primitives for new practical applications, also in the relativistic setting when relevant, or as new primitives and protocols with modular, realistic integration of solutions from different cryptographic approaches, with focus on beyond-QKD applications and with gradual release on trust in hardware;

2.Analysis of the applicability and strength of the results compared to their best classical-only counterpart, critical analysis of the formal assumptions and of performance, security proofs;

3.Investigation of fundamental aspects of quantum information processing tasks, their eventual limits; and/or the connection between quantum computing and cryptography for insights for stronger cryptographic foundations;

4.Roadmap for quantum cryptography and networks functionalities.

Scope:

The action supports research on new primitives and protocols beyond QKD for security and trust-based applications, by combining different cryptographic approaches and by exploiting insights from quantum information science, to demonstrate compelling quases of quantum cryptographic advantage and obtain foundational results on the unique features of quantum protocols. The goal is to build on the basis of insights from the field of real-world, applied cryptography and the vision from the quantum domain on future entanglement-based networks, the foundations of a new cryptography, that will support mid-term hybrid classical-quantum and further in the future almost fully quantum networks. The design of such new foundations may need entirely new paradigms whose design requires different expertise.

The proposal should target some of the following areas and lead to a roadmap:

1.Development of quantum primitives which have classical equivalent, of new quantum primitives not possible classically (or without trusted hardware), and of alternative solutions improving quantum cryptography protocols using classical cryptography solutions (in particular PQC), by flexibly incorporating various cryptographic components, with some beneficial aspects such as performance improvements (run time, energy usage, less requirements on HW etc.)

2.Analysis of the applicability and strength of the results compared to their best classical-only counterpart, critical analysis of the formal assumptions, rigorous security proofs, case-by-case analysis of composable security and of performance.Connection between quantum information processing tasks and holography, and transfer to the cryptographic context, such as, among others, non-local quantum computation for position-verification schemes and spoofing schemes as means of establishing trust, via foundational insights on entanglement and quantum correlations; connection between quantum computing and cryptography providing stronger cryptographic foundations.

3.Development of a quantum cryptography roadmap, which identifies challenges for the technical realisation and scaling of applications and presenting the implications for the best hardware and architecture settings for both near-term and long-term applications of quantum networks.

Proposals should include, in a balanced manner, quantum scientists and researchers from PQC with experience on real-world, applied cryptography and with interest in quantum protocols and new paradigms for future networks.

Budget 191   192

Budget line(s)

2026 Budget (EUR million)

2027 Budget (EUR million)

Calls

HORIZON-CL3-2026-01

131.00

from 01.020230

131.00

HORIZON-CL3-2027-01

129.50

from 01.020230

129.50

Other actions

Expert contract action

0.80

0.80

from 01.020230

0.80

0.80

Public procurement

2.13

1.52

from 01.020230

2.13

1.52

Indirectly managed action

56.20

71.80

from 01.020230

56.20

71.80

Estimated total budget

190.13

203.62

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(2)    JOIN(2025), 130 final.
(3)    In line with the UNCRPD, the EU has a long-standing commitment to provide humanitarian aid that is inclusive and accessible to persons with disabilities. Situation of persons with disabilities in the case of meteorological, hydrological, geophysical events and armed conflicts needs to be specifically addressed by ensuring a truly inclusive preparedness where persons with disabilities are provided with the right tools on how to act in emergencies.
(4)    To this end, the Commission and Member States have in place a mechanism for strategic planning and coordination of R&D related to the Copernicus Security Services (CSS), which maps current operational services and on-going and planned R&D initiatives, as well as it identifies end-user operational requirements and promotes sharing of information between projects with common interests. The mechanism drives R&D objectives listed in a Strategic Research Agenda (SRA) updated on a yearly basis. Engagement in the CSS-SRA information sharing process is therefore sought, for those projects planning to use Earth Observation and associated services for civil security applications.
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(9) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(10)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(11) The Director-General responsible may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The Director-General responsible for the call may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(12)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
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(42)    In the context of this Destination, ‘Police Authorities’ means public authorities explicitly designated by national law, or other entities legally mandated by the competent national authority, for the prevention, detection and/or investigation of terrorist offences or other criminal offences, specifically excluding police academies, forensic institutes, training facilities as well as border and customs authorities.
(43)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
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(45)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(46)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
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(48)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
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(50)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
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(52)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
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(55)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
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(58)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
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(74)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
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(80)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(81)    https://environment.ec.europa.eu/topics/forests/deforestation/regulation-deforestation-free-products_en
(82)    Directive (EU) 2022/2557.
(83)    Directive (EU) 2022/2555.
(84)    COM/2025/148 final
(85)    COM (2020) 795 final.
(86)    JOIN(2025) 130 final
(87)    COM (2021) 82 final.
(88)    JOIN (2020) 18 final.
(89)    Council of the EU 11205/14 JOIN(2023) 8 final.
(90)    REGULATION (EC) No 300/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 11 March 2008 on common rules in the field of civil aviation security and repealing Regulation (EC) No 2320/2002.
(91)    JOIN(2023) 20 final.
(92)    JOIN (2016) 18 final.
(93)    JOIN (2018) 16 final.
(94)    COM (2023) 659 final.
(95)    JOIN (2023) 9 final.
(96)    (2023/C 56/01); COM (2023) 61 final.
(97)    JOIN(2025), 130 final.
(98)    JOIN(2025) 9 final.
(99)    https://circabc.europa.eu/ui/group/1c566741-ee2f-41e7-a915-7bd88bae7c03/library/b560bc22-6a61-4b63-b62b-a7fe890ea177/details
(100)    https://home-affairs.ec.europa.eu/networks/ceris-community-european-research-and-innovation-security_en
(101)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(102)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(103)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(104)    Including, but not limited to, infrastructures addressed by the revised EU Maritime Security Strategy (JOIN/2023/8) and the European Port Strategy.
(105)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(106)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(107)    Disaster management refers here to systems for preventing, preparing for and responding to natural and man-made disasters in the spirit of Decision No 1313/2013/EU. The protection they provide shall cover primarily people, but also the environment and property, including cultural heritage, against all kinds of natural and man-made disasters, including the consequences of acts of terrorism, technological, radiological or environmental disasters, marine pollution, hydrogeological instability and acute health emergencies, occurring inside or outside the Union. In the case of the consequences of acts of terrorism or radiological disasters, it should cover only preparedness and response actions.
(108)    JOIN(2025) 130 final.
(109)    COM/2023/61 final.
(110)    UNDRR, Sendai Framework for Disaster Risk Reduction 2015-2030.
(111)    See the UCPM scientific needs assessment on disaster risk management: https://civil-protection-knowledge-network.europa.eu/media/outcome-report-scientific-research-needs-exercise
(112)    Under the Decision, the protection they provide shall cover primarily people, but also the environment and property, including cultural heritage, against all kinds of natural and human-made disasters, including the consequences of acts of terrorism, technological, radiological or environmental disasters, marine pollution, hydrogeological instability and acute health emergencies, occurring inside or outside the Union. In the case of the consequences of acts of terrorism or radiological disasters, it should cover only preparedness and response actions.
(113)    https://redcross.eu
(114)    https://home-affairs.ec.europa.eu/networks/ceris-community-european-research-and-innovation-security_en
(115)    Authorities in charge of disaster risk entail public bodies operating at the national level that hold legally defined responsibilities in the area of disaster risk management. This includes national civil protection authorities as well as other institutions that can demonstrate, through appropriate legal or administrative acts, a formal mandate to design, coordinate, or implement national disaster risk prevention, preparedness or response measures.
(116)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(117)    Knowledge for Action in Prevention and Preparedness (KAPP) - European Commission - https://civil-protection-humanitarian-aid.ec.europa.eu/funding-evaluations/financing-civil-protection/cp-calls-proposals/knowledge-action-prevention-and-preparedness-kapp-0_en
(118)    Authorities in charge of disaster risk or crisis communication entail public bodies operating at the national level that hold legally defined responsibilities in the area of disaster risk management. This includes national civil protection authorities as well as other institutions that can demonstrate, through appropriate legal or administrative acts, a formal mandate to design, coordinate, or implement national disaster risk prevention, preparedness, response, or crisis communication measures.
(119)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(120)    Knowledge for Action in Prevention and Preparedness (KAPP) - European Commission - https://civil-protection-humanitarian-aid.ec.europa.eu/funding-evaluations/financing-civil-protection/cp-calls-proposals/knowledge-action-prevention-and-preparedness-kapp-0_en
(121)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(122)    https://civil-protection-knowledge-network.europa.eu/media/ecpp-capacities-brochure
(123)    https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52025DC0286
(124)    https://civil-protection-humanitarian-aid.ec.europa.eu/what/civil-protection/resceu_en
(125)    Knowledge for Action in Prevention and Preparedness (KAPP) - European Commission - https://civil-protection-humanitarian-aid.ec.europa.eu/funding-evaluations/financing-civil-protection/cp-calls-proposals/knowledge-action-prevention-and-preparedness-kapp-0_en
(126)    Authorities in charge of disaster risk entail public bodies operating at the national level that hold legally defined responsibilities in the area of disaster risk management. This includes national civil protection authorities as well as other institutions that can demonstrate, through appropriate legal or administrative acts, a formal mandate to design, coordinate, or implement disaster risk prevention, preparedness, or response, measures.
(127)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(128)    eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52025DC0286
(129)    Authorities in charge of disaster risk entail public bodies operating at the national level that hold legally defined responsibilities in the area of disaster risk management. This includes national civil protection authorities as well as other institutions that can demonstrate, through appropriate legal or administrative acts, a formal mandate to design, coordinate, or implement disaster risk prevention, preparedness, or response, measures.
(130)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(131)    https://www.eea.europa.eu/en/analysis/publications/european-climate-risk-assessment
(132)    COM/2024/130 final, Preventing and managing disaster risk in Europe, https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A52024DC0130
(133)    HORIZON-MISS-2026-01-CLIMA-04: Bridging the gap between disaster risk management and climate adaptation
(134)    https://commission.europa.eu/topics/defence/safer-together-path-towards-fully-prepared-union_en
(135)    Training centres are national, regional or local infrastructures, generally ruled by governments or professional organisations, aiming at training practitioners (first responders, civil protection units etc.) in near-real operational crisis situations.
(136)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(137)    https://civil-protection-knowledge-network.europa.eu/media/ecpp-capacities-brochure
(138)    https://civil-protection-humanitarian-aid.ec.europa.eu/what/civil-protection/resceu_en
(139)    https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52025DC0286
(140)    Knowledge for Action in Prevention and Preparedness (KAPP) - European Commission - https://civil-protection-humanitarian-aid.ec.europa.eu/funding-evaluations/financing-civil-protection/cp-calls-proposals/knowledge-action-prevention-and-preparedness-kapp-0_en
(141)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(142)    In the context of the European Union, youth is typically defined as individuals between the ages of 13 and 30. This definition aligns with the EU's Youth Strategy, which focuses on supporting young people’s personal and professional development. However, some EU programs may adjust the age range slightly depending on the specific context (e.g., education, employment, or participation), but the 13-30 age bracket is recognized in EU policies related to youth.
(143)    Knowledge for Action in Prevention and Preparedness (KAPP) - European Commission - https://civil-protection-humanitarian-aid.ec.europa.eu/funding-evaluations/financing-civil-protection/cp-calls-proposals/knowledge-action-prevention-and-preparedness-kapp-0_en
(144)    Authorities in charge of disaster risk and crisis communication entail public bodies operating at the national level that hold legally defined responsibilities in the area of disaster risk management. This includes national civil protection authorities as well as other institutions that can demonstrate, through appropriate legal or administrative acts, a formal mandate to design, coordinate, or implement disaster risk prevention, preparedness, response or crisis communication measures.
(145)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(146)    AI Act: https://digital-strategy.ec.europa.eu/en/policies/regulatory-framework-ai
(147)    https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52025DC0286
(148)    Knowledge for Action in Prevention and Preparedness (KAPP) - European Commission - https://civil-protection-humanitarian-aid.ec.europa.eu/funding-evaluations/financing-civil-protection/cp-calls-proposals/knowledge-action-prevention-and-preparedness-kapp-0_en
(149)    Authorities in charge of disaster risk or crisis communication entail public bodies operating at the national level that hold legally defined responsibilities in the area of disaster risk management. This includes national civil protection authorities as well as other institutions that can demonstrate, through appropriate legal or administrative acts, a formal mandate to design, coordinate, or implement disaster risk prevention, preparedness, response or crisis communication measures.
(150)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(151)    https://civil-protection-knowledge-network.europa.eu/UCPM-training-programme
(152)    https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52025DC0286
(153)    Knowledge for Action in Prevention and Preparedness (KAPP) - European Commission - https://civil-protection-humanitarian-aid.ec.europa.eu/funding-evaluations/financing-civil-protection/cp-calls-proposals/knowledge-action-prevention-and-preparedness-kapp-0_en
(154)    COM(2004) 72.
(155)    Through the interaction of public authorities, academia, industry and the public.
(156)    For the purpose of the work programme, the terms “Capability” should be understood as "the ability to pursue a particular policy priority or achieve a desired operational effect”. The term “capability” is often interchanged with the term “capacity”, but this should be avoided. “Capacity” could refer to an amount or volume of which one organisation could have enough or not. On the other hand, “capability” refers to an ability, an aptitude or a process that can be developed or improved in consonance with the ultimate objective of the organisation.
(157)    https://home-affairs.ec.europa.eu/document/download/ff888398-0b0a-4511-9717-ad41beb22314_en?filename=SWD-2021-422_en.PDF
(158)    https://home-affairs.ec.europa.eu/networks/ceris-community-european-research-and-innovation-security_en
(159)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(160)    In the context of this Destination, the concept of ‘disruptive technological innovations’ refers to breakthrough technologies starting at low or very low TRL (<4) and holding the promise of inducing a paradigm shift in the way civil security operations are currently carried out, e.g. by significantly improving performance and/or reducing costs if further developed.
(161)    See, for instance, Conte, N., Maleville, A. d., Favino, R., Garcia Monreal, E., Montanari, E. et al., Emerging risks and opportunities for EU internal security stemming from new technologies, Publications Office of the European Union, 2025, https://data.europa.eu/doi/10.2760/9617320
(162)    See General Annexes page 12 on the Consortium Composition as regards Pre-commercial Procurement.
(163)    Under this topic, the participation is required of minimum three procurers as beneficiaries in the buyer’s group for the PCP. The third procurer in the buyer’s group can be a private procurer or an NGO that provides similar services of public interest as the public procurers.
(164)    Under this topic, the participation is required of minimum three procurers as beneficiaries in the buyer’s group for the PCP, out of which minimum two must be independent legal entities that are public procurers, each established in a different Member State or Associated Country and with at least one of them established in a Member State. The third procurer in the buyer’s group can be a private procurer or an NGO that provides similar services of public interest as the public procurers.
(165)    See General Annex H of the Horizon Europe Work Programme.
(166)    See General Annexes page 12 on the Consortium Composition as regards Public procurement of innovative solutions.
(167)    Under this topic, the participation is required of minimum three procurers as beneficiaries in the buyer’s group for the PPI. The third procurer in the buyer’s group can be a private procurer or an NGO that provides similar services of public interest as the public procurers.
(168)    For more information see General Annex H of Horizon Europe Work Programme – Specific Conditions for Actions with PCP/PPI.
(169)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(170)    See Commission Recommendation 2003/361/EC concerning the definition of micro, small and medium-sized enterprises, as well as the User Guide for SME definition.
(171)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(172)    If a MIDCAP is included in the proposal, it could also take the role of coordinator.
(173)    OJ L, 2024/795, 29.2.2024, ELI: http://data.europa.eu/eli/reg/2024/795/oj
(174)    https://strategic-technologies.europa.eu/index_en
(175)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(176)    See General Annexes page 12 on the Consortium Composition as regards Public procurement of innovative solutions.
(177)    Under this topic, the participation is required of minimum three procurers as beneficiaries in the buyer’s group for the PPI. The third procurer in the buyer’s group can be a private procurer or an NGO that provides similar services of public interest as the public procurers.
(178)    See General Annex H of the Horizon Europe Work Programme.
(179)    The Commission intends to transfer to the ECCC an indicative amount of 0.085 M EUR from 2026 and 0.12 M EUR from 2027 related to the implementation of the delegated grant agreements. See indirectly managed action delegated to the ECCC.
(180) The Executive Director of the ECCC may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026.    The Executive Director-of the ECCC may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(181)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(182)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link:https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(183)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link:https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(184)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link:https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(185) The Executive Director of the ECCC may delay the deadline(s) by up to two months.All deadlines are at 17.00.00 Brussels local time.The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2027.    The Executive Director-of the ECCC may decide to open the call up to one month prior to or after the envisaged date(s) of opening.
(186)    Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.
(187)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link:https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(188)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link:https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(189)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link:https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(190)    This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link:https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf
(191) The budget amounts are subject to the availability of the appropriations provided for in the general budget of the Union for 2026 and 2027.    The budget figures given in this table are rounded to two decimal places.
(192) The contribution from Cluster 3 for year 2027 is EUR 11.51 million for the Missions work programme part and EUR 2.05 million for the New European Bauhaus Facility work programme part.    The contribution from Cluster 3 for year 2026 is EUR 9.51 million for the Missions work programme part and EUR 1.75 million for the New European Bauhaus Facility work programme part.
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EN

Annex VII

Horizon Europe

Work Programme 2026-2027

7. Digital, Industry and Space

Table of contents

Introduction    

Calls    

Call - INDUSTRY    

Overview of this call    

Call - INDUSTRY-two-stage    

Overview of this call    

Call - INDUSTRY    

Overview of this call    

Call - INDUSTRY-two-stage    

Overview of this call    

Call - INDUSTRY-FTRI    

Overview of this call    

Call - SPACE    

Overview of this call    

Call - SPACE    

Overview of this call    

Call - DIGITAL    

Overview of this call    

Call - DIGITAL    

Overview of this call    

Call - DIGITAL    

Overview of this call    

Call - DIGITAL    

Overview of this call    

Destinations    

Destination: Leadership in materials and production for Europe    

Sustainable Advanced Materials, Raw Materials and Chemicals    

HORIZON-CL4-2026-02-MAT-PROD-21-two-stage: Development of safe and sustainable alternatives to substances of concern (IA)    

HORIZON-CL4-2027-01-MAT-PROD-22: Innovative advanced materials and new production processes – reducing dependencies on Critical and Strategic Raw Materials (IA) (Innovative Advanced Materials for the EU and Processes4Planet partnerships)    

HORIZON-CL4-2026-01-MAT-PROD-23: Accelerating the discovery and development of chemicals and innovative advanced materials through digitalisation and artificial intelligence (IA) (Innovative Advanced Materials for the EU partnership)    

HORIZON-CL4-2026-01-MAT-PROD-24: Cooperation on innovative advanced materials with Japan (CSA)    

Fast-tracking Circularity    

HORIZON-CL4-2026-01-MAT-PROD-01: Advanced manufacturing for key products (IA) (Made in Europe partnership)    

HORIZON-CL4-2027-01-MAT-PROD-02: Advanced manufacturing for key products (IA) (Made in Europe partnership)    

HORIZON-CL4-2027-01-MAT-PROD-03: Factory processes and automation for de- and re-manufacturing (RIA) (Made in Europe partnership)    

HORIZON-CL4-2026-01-MAT-PROD-04: Optimise the usage of resources in a circular economy (RIA) (Processes4Planet and Clean Steel partnerships)    

HORIZON-CL4-2026-01-MAT-PROD-05: Circular innovative advanced materials: facilitating the transition from design to markets (RIA) (Innovative Advanced Materials for the EU and Made in Europe partnerships)    

HORIZON-CL4-2027-01-MAT-PROD-06: Circular innovative advanced materials: facilitating the transition from design to markets (RIA) (Innovative Advanced Materials for the EU and Made in Europe partnerships)    

HORIZON-CL4-2027-01-MAT-PROD-08: Textile circularity through advanced processing and manufacturing technologies and system approaches (IA) (Textiles for the Future partnership)    

Disruptive technologies for carbon capture and clean energy use    

HORIZON-CL4-2026-01-MAT-PROD-31: Efficient capture / purification / utilisation of CO2 for the production of competitive products (RIA) (Processes4Planet partnership)    

HORIZON-CL4-2027-02-MAT-PROD-32-two-stage: Efficient energy input from renewable sources and energy management in the process industries (IA) (Processes4Planet and Innovative Advanced Materials for the EU partnerships)    

Technology infrastructure, knowledge valorisation and support for scaleups and startups    

HORIZON-CL4-2026-01-MAT-PROD-41: Enhancing industry-academia knowledge exchange in Social Sciences and Humanities (SSH) (CSA)    

HORIZON-CL4-2027-01-MAT-PROD-42: Unlocking the potential of academic intellectual assets for industry, SMEs and startups (CSA)    

HORIZON-CL4-2027-01-MAT-PROD-61: Fast Track to Research and Innovation for breakthroughs in industrial technologies (Research and Innovation Action)    

HORIZON-CL4-2027-01-MAT-PROD-62: Fast Track to Innovation for breakthroughs in the Chemical Industry Action Plan (Research and Innovation Action)    

HORIZON-CL4-2026-01-MAT-PROD-44: Attracting management talent for capacity building for Technology Infrastructures staff members (CSA)    

HORIZON-CL4-2026-01-MAT-PROD-45: Pilot access schemes to Technology Infrastructures for European startups, scaleups and innovative SMEs (CSA)    

HORIZON-CL4-2026-01-MAT-PROD-46: Mapping and service finder for Technology Infrastructures (CSA)    

HORIZON-CL4-2027-01-MAT-PROD-47: Pilot access schemes to Technology Infrastructures for European startups, scaleups and innovative SMEs (CSA)    

HORIZON-CL4-2026-01-MAT-PROD-48: ‘Proof of market’ to improve valorisation and commercialisation of Horizon generated R&I results (IA)    

HORIZON-CL4-2027-01-MAT-PROD-49: ‘Proof of market’ to improve valorisation and commercialisation of Horizon generated R&I results (IA)    

Raw Materials    

HORIZON-CL4-2026-01-MAT-PROD-11: Innovative technologies and tools for exploration and data modelling of raw materials (RIA)    

HORIZON-CL4-2026-01-MAT-PROD-12: Technologies for innovative extraction of critical raw materials (RIA)    

HORIZON-CL4-2026-01-MAT-PROD-13: Monitoring of secondary raw materials (CSA)    

HORIZON-CL4-2026-01-MAT-PROD-14: Improving availability of secondary raw materials through recycling (IA)    

HORIZON-CL4-2027-01-MAT-PROD-16: Technologies for innovative processing of raw materials (IA)    

HORIZON-CL4-2027-01-MAT-PROD-17: Expert network on Critical raw materials (CSA)    

Innovative Advanced Materials-based Technologies    

HORIZON-CL4-2026-05-MAT-PROD-25: New or enhanced Innovative Advanced Materials (IAM) enabled sensing functionality (RIA)    

Destination: Developing an agile and secure single market and infrastructure for data-services and trustworthy artificial intelligence services    

Telco-Edge-Cloud continuum/ 3C Network (Connected Collaborative Computing) and Open Internet Stack    

HORIZON-CL4-2027-04-DATA-08: Demand-side 3C pilot demonstrators on converged Telco Edge Cloud Infrastructure (IA)    

HORIZON-CL4-2026-04-DATA-02: Open Internet Stack Sovereign Solutions (RIA)    

HORIZON-CL4-2026-04-DATA-03: Open Internet Stack Support for Scale (CSA)    

Achieving the end-to-end AI compute continuum    

HORIZON-CL4-2027-04-DATA-03: New approaches for decentralized, federated and sustainable AI data processing (RIA)    

HORIZON-CL4-2027-04-DATA-09: Energy efficiency and sustainability of AI data processing in Data Centres (IA)    

Data (under AI, Data and Robotics partnership)    

HORIZON-CL4-2026-04-DATA-06: Efficient and compliant access to and use of data (IA) (AI, Data and Robotics partnership)    

Destination: Achieving open strategic autonomy in digital and emerging enabling technologies    

AI Continent    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-01: Apply AI: Pilot of the “Science for AI” Pillar of RAISE (“Resource for AI science in Europe”) (RIA)    

HORIZON-CL4-2027-04-DIGITAL-EMERGING-11: EU Frontier AI Initiative: Developing frontier AI solutions that are safe and computationally efficient within Apply AI (RIA)    

HORIZON-CL4-2026-05-DIGITAL-EMERGING-02: Next-Generation AI Agents for Real-World Applications in the Apply AI sectors (RIA) (Partnership in AI, Data and Robotics)    

HORIZON-CL4-2027-04-DIGITAL-EMERGING-04: Apply AI: Challenge-Driven AI Innovation Booster in Apply AI prioritised sectors (RIA) (Partnership in AI, Data and Robotics)    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-19: Challenge-Driven GenAI4EU Booster in Apply AI prioritised sectors (RIA) (AI/Data/Robotics Partnership)    

HORIZON-CL4-2026-05-DIGITAL-EMERGING-03: Apply AI: Next-Generation Agile and Intelligent Robotics Platforms for Industrial and Service Applications (Partnership in AI, Data and Robotics) (RIA)    

HORIZON-CL4-2027-04-DIGITAL-EMERGING-05: Apply AI: AI-Driven Robotics for Industry: Enabling System Integration and Adoption (IA) (Partnership in AI, Data and Robotics)    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-08: Apply AI: Robotics for Manufacturing: Advancing Core Skills through Technical Challenges (RIA) (Partnership in AI, Data and Robotics)    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-09: Advanced Local Digital Twins using AI for Early Warning and Preparedness (IA)    

HORIZON-CL4-2027-04-DIGITAL-EMERGING-06: International cooperation in AI (IA)    

Quantum    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-11: Grand Challenge on Quantum Sensors for Inertial Navigation    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-12: Standards for Quantum Technologies – Coordination and Support Action (CSA)    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-18: Large-Scale Photonic Quantum Computing Platform Technologies (RIA)    

Photonics    

HORIZON-CL4-2027-05-DIGITAL-EMERGING-03: Advanced integrated photonic devices for extended features and ultra-low power consumption (RIA) (Photonics Partnership)    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-14: Networking and Future Photonics Strategy (CSA) (Photonics Partnership)    

Semiconductors    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-15: Strengthening the cooperation of semiconductor-intensive EU regions (CSA)    

Other emerging technologies    

HORIZON-CL4-2027-04-DIGITAL-EMERGING-10: Horizon scanning and foresight in future enabling digital technologies (CSA)    

HORIZON-CL4-2026-04-DIGITAL-EMERGING-17: Fostering 2-Dimensional Materials (2DM) based emerging and enabling technologies (CSA)    

AI for manufacturing and energy-intensive industries    

HORIZON-CL4-2026-02-DIGITAL-EMERGING-51-two-stage: AI improved advanced manufacturing and production processes in factories (RIA) (Made in Europe and AI, Data and Robotics partnerships)    

HORIZON-CL4-2027-02-DIGITAL-EMERGING-52-two-stage: New approaches for Human/AI collaboration for the workforce of the future (RIA) (Made in Europe and AI, Data and Robotics partnerships)    

HORIZON-CL4-2026-02-DIGITAL-EMERGING-53-two-stage: Innovative AI methods and technologies for the process industries (RIA) (Processes4Planet and AI, Data and Robotics partnerships)    

Destination: Open Strategic Autonomy in Developing, Deploying and Using Global Space-Based Infrastructure, Services, Applications and Data    

Heading 1 - Accessing Space    

HORIZON-CL4-2026-SPACE-03-11: Reinforcing EU autonomous access to space through EU-based spaceports    

HORIZON-CL4-2027-SPACE-03-12: Digital solutions for autonomy for space transportation systems, design and simulation tools - Digital enablers and building blocks (Space Partnership)    

Heading 2 - Acting in Space    

HORIZON-CL4-2027-SPACE-03-21: ISOS4I Pilot Mission Integrated Ground Test and consolidation of space-compatible USI solutions    

Heading 3 - Using Space on Earth - Telecommunications    

Headings 3&4 - Using Space on Earth - Telecommunications and Earth Observation    

HORIZON-CL4-2026-SPACE-03-31: Digital enablers and building-blocks for Earth Observation and Satellite telecommunication for Space solutions (Space Partnership)    

HORIZON-CL4-2026-SPACE-03-32: Preparing demonstration missions for Earth Observation and Satellite telecommunication for Space solutions (Space Partnership)    

HORIZON-CL4-2027-SPACE-03-33: Digital enablers and building blocks for collaborative Earth Observation and Satellite telecommunications for Space solutions (Space Partnership)    

HORIZON-CL4-2027-SPACE-03-34: Preparing demonstration missions for collaborative Earth Observation and Satellite telecommunication for Space solutions (Space Partnership)    

Heading 5 - Using Space on Earth - Satellite navigation    

Heading 6 - Space sciences and exploration    

HORIZON-CL4-2026-SPACE-03-61: Scientific analysis and exploitation of space data    

Heading 7 - Monitoring Space    

Heading 8 - Boosting Space through EU non-dependence for critical space technologies    

HORIZON-CL4-2026-SPACE-03-81: Space critical EEE components for EU non-dependence – Radiation Hard FPGA on 7nm    

HORIZON-CL4-2026-SPACE-03-82: Space critical EEE components for EU non-dependence – GaN MMICs mm-Wave Foundations (Phase A): Development and Industrialization of Semi-insulating SiC Substrate Capabilities    

HORIZON-CL4-2026-SPACE-03-85: Critical Facilities Serving Space EEE components for EU non-dependence – High and Very High Energy Irradiation Test Facility Market Deployment    

HORIZON-CL4-2026-SPACE-03-86: Space critical Equipment for EU non-dependence – Space Refuelling Interface    

HORIZON-CL4-2027-SPACE-03-83: Space critical EEE components for EU non-dependence    

HORIZON-CL4-2027-SPACE-03-84: Space critical equipment for EU non-dependence    

Heading 9 - Boosting Space through innovative space technologies    

HORIZON-CL4-2027-SPACE-03-71: Quantum Space Gravimetry topic    

Heading 10 - Boosting Space through IOD/IOV opportunities    

Heading 11 - Boosting Space through support to entrepreneurship    

Heading 12 : Boosting Space through support to the Space Act and cybersecurity    

Destination: Digital and industrial technologies driving human-centric innovation    

Virtual Worlds – Web 4.0 (Partnership)    

HORIZON-CL4-2026-04-HUMAN-01: Developing and demonstrating core technologies for Virtual Worlds and Web 4.0 (IA) (Virtual worlds Partnership)    

HORIZON-CL4-2026-04-HUMAN-02: Web 4.0 architectural framework and Open Internet Stack applications for virtual worlds (RIA)    

HORIZON-CL4-2027-04-HUMAN-01: Advanced and Innovative hardware components for Virtual Worlds (RIA) (Virtual Worlds Partnership)    

HORIZON-CL4-2027-04-HUMAN-02: Create a thriving and competitive Virtual Worlds and Web 4.0 ecosystem (CSA) (Virtual Worlds Partnership)    

STANDARDISATION – INTERNATIONAL    

HORIZON-CL4-2027-04-HUMAN-07: Facilitate the engagement of European stakeholders in international digital standardisation (CSA)    

Other actions not subject to calls for proposals    

Public procurements    

Space    

1. Heading 11 of Space - Boosting Space through support to entrepreneurship - CASSINI activities    

2. Space events, Studies and Platforms    

3. Boosting Space through support to the Space Act and cybersecurity    

4. Industry    

4.1. Study on the societal benefits in the use of collaborative licensing models for intellectual assets management    

4.2. Comparative study on strategies, practices and tools for knowledge valorisation in five jurisdictions outside the EU    

4.3. Framework for effective licensing of intellectual assets stemming from publicly funded research    

4.4. Research security and intellectual assets management (study)    

4.5. RDI database for evidence-based policy. Keeping data up-to-date and integrating new sectors for analysis    

4.6. Raw materials events    

4.7. Study for the Critical Raw Materials Centre    

4.8. Anthropometric dataspace supporting standards development    

4.9. Conferences, outreach, studies and other activities on the impact of Artificial Intelligence in R&I and other critical technologies    

5. Digital    

5.1. Emergency response and resources allocation    

5.2. AI powered Digital Twin for Reconstruction    

5.3. Digital conferences, outreach, studies and other activities    

Subscription Actions    

1. Support to Hydrogen in the Economy    

Other budget implementation instruments    

1. Project monitoring and use of individual experts (space)    

2. Project monitoring and use of individual experts (Industry)    

3. Commission expert group: “RAISE High-level Academic Advisory Board”    

4. Use of individual experts to support raw materials policy (GROW and HaDEA)    

5. Use of individual experts to support raw materials policy (HaDEA)    

6. External Expertise Digital (CNECT)    

7. External Expertise Digital (HADEA)    

Grants to identified beneficiaries    

Industry    

1. Presidency Event (conference) on AI in Science 2026    

2. Presidency Event (conference) on AI in Science 2027    

3. Presidency Event (conference): Technologies for Europe 2027    

4. Presidency Event (conference): Technologies for Europe 2028    

Digital    

1. Organisation of the Presidency Event European Quantum Technologies Conference (EQTC) 2026    

2. Organisation of the Presidency Event European Quantum Technologies Conference (EQTC) 2027    

3. Presidency Event 2026    

4. Presidency Event 2027    

Heading 7 of Space - Monitoring Space    

1. SST Sensors and Processing    

2. Consolidate commercial SST capabilities on sensors    

Scientific and technical services by the Joint Research Centre    

1. Industrial Research & Innovation – Industrial R&D Investment Scoreboard and monitoring and analysis of data and dynamics    

2. JRC Support to implement Article 34 relating to the adoption of delegated acts to supplement Art 28, 29, 31 and 33 on alignment with other Union harmonisation legislation    

3. JRC Support to Critical Raw Materials Act, Strategic Technologies value chains and Energy-Intensive Technologies    

Indirectly managed actions    

1. ESA.1 - Heading 5 of Space - Using Space on Earth - Satellite navigation - EGNSS Evolution : Technology and infrastructure-related R&I activities    

2. ESA.2 - Heading 3 of Space - Using Space on Earth - Telecommunications - IRIS2 infrastructure: Development and Validation    

3. ESA.3 - Heading 10 of Space - Boosting Space through IOD/IOV opportunities - IOV-IOD service    

4. EUSPA.1 - Applications for EGNSS and for Copernicus    

5. Quantum Top-Up to InvestEU: Grand Challenge Phase 2    

6. Support to implementation of Strategic Projects under the Critical Raw Materials Act    

Specific Grant Agreements    

1. Quantum Computing – Call for the 2nd SGA for the Millenion FPA (trapped-ions)    

2. Quantum Computing – Call for the 2nd SGA for the OpenSuperQPlus FPA (superconducting)    

3. Quantum Computing & Simulation – Call for the 2nd SGA for the PASQuanS2 FPA    

4. Quantum Communication – Call for the 2nd SGA for the QSNP FPA (QKD)    

5. Quantum Testing Infrastructure – Call for the 2nd SGA for the Qu-Test FPA    

6. Quantum Experimental Pilot Lines – Call for the 2nd SGA for the Qu-Pilot FPA    

Budget    

Introduction

The Work Programme 2026-27 will support digital, industrial and space technologies to address the three core areas of the Competitiveness Compass adopted by the European Commission on 29 January 2025: (i) closing the innovation gap through innovative technologies geared towards deployment; (ii) supporting decarbonisation and competitiveness through focused industrial technologies; and (iii) reducing excessive dependencies and increasing security.

Cluster ‘Digital, Industry and Space’ will serve these goals through substantial R&I investments, often complemented by private investments through partnerships, across different technology readiness levels; and by integrating technological, environmental and social objectives into innovation.

Progress in digital and industrial technologies, including in space, shapes all sectors of the economy and society. These technologies transform the way industry develops, create new products and services, and are central to any sustainable future. Research and innovation to support the green and digital transition, and attain and maintain strategic capacities such Access to Space or Act in Space, are a key to Europe’s competitiveness and open strategic autonomy, to industrial sustainability and to setting human-centred standards.

Resilience and technological sovereignty have become renewed priorities for the EU due to the current geopolitical and economic context that exposed vulnerabilities in critical value chains. In this context it is imperative to contribute to the implementation of the Net-Zero Industry Act (NZIA) and the Critical Raw Materials Act (CRMA); and to reinforce Europe’s position in digital technologies, high-performance computing, Artificial Intelligence, robotics, secure communication, virtual worlds, critical Space technologies, advanced and sustainable manufacturing technologies, advanced materials , sustainable raw and the circular economy as applied to industries.

Cluster 4, ‘Digital, Industry and Space’ aims to shape competitive and trusted technologies for EU leadership in these technologies; to enable production and consumption respecting the boundaries of our planet; and to maximise the benefits for all parts of society in the variety of social, economic and territorial contexts in Europe. It will for example boost Europe leadership and competitiveness on Artificial Intelligence innovation (AI), in line with the Apply AI Strategy, and leading the way on making AI safer and more trustworthy, and on tackling the risks stemming from its misuse. Similarly, it will ease the exploitation of untapped data potential while promoting high standards of data protection.

This cluster will also support the Clean Industrial Deal, by driving decarbonisation and circularity in the manufacturing, energy-intensive and construction industries; and by providing the innovative advanced materials and advanced manufacturing technologies that are needed for a net-zero economy. It aims to position the European Union as a technology and industrial leader in clean technologies.

In this Work Programme, a new Destination brings together the research and innovation for a globally competitive European industry through the twin green and digital transition, and the availability, development, use and disposal of chemicals, advanced materials and critical raw materials. Synergies between partnerships towards these closely intertwined goals of the green and digital transitions and resilience are strongly encouraged.

Actions under this cluster will support key enabling technologies that are strategically important for Europe’s future, and will deliver on the following six expected impacts in the Strategic Plan, through matching Destinations in this Work Programme (the first two impacts are served by a single Destination):

15. Achieving global leadership in climate-neutral, circular and digitised industrial and digital value chains

16. Achieving technological leadership for Europe’s open strategic autonomy in raw materials, chemicals and innovative materials

17. Developing an agile and secure single market and infrastructure for data-services and trustworthy artificial intelligence services

18. Achieving open strategic autonomy in digital and emerging enabling technologies

19. Achieving open strategic autonomy in global space-based infrastructures, services, applications and data

20. Digital and industrial technologies driving human-centric innovation

In addition, several actions are crucial to support our European Economic Security Strategy, notably its 'promote' pillar that focuses on enhancing the Union's competitiveness and industrial base, as well as investing in research and innovation for strategic and dual-use technologies, as permitted by the Horizon Europe regulation.

Where data and their exchange are relevant, proposals should adhere to the FAIR data principles and adopt as appropriate data standards and good practices on data sharing and access.

Eligibility to participate is also subject to the ‘Participation of Chinese universities linked to the Ministry of Industry and Information Technology (MIIT)’ eligibility condition (see General Annex B of the General Annexes).

Calls

Call - INDUSTRY

HORIZON-CL4-2026-01

Overview of this call 1

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 2

Indicative number of projects expected to be funded

2026

Opening: 06 Jan 2026

Deadline(s): 21 Apr 2026

Destination: Leadership in materials and production for Europe

HORIZON-CL4-2026-01-MAT-PROD-23: Accelerating the discovery and development of chemicals and innovative advanced materials through digitalisation and artificial intelligence (IA) (Innovative Advanced Materials for the EU partnership)

IA

50.00

Around 13.00

4

HORIZON-CL4-2026-01-MAT-PROD-24: Cooperation on innovative advanced materials with Japan (CSA)

CSA

0.80

Around 0.80

1

HORIZON-CL4-2026-01-MAT-PROD-01: Advanced manufacturing for key products (IA) (Made in Europe partnership)

IA

38.00

6.00 to 8.00

6

HORIZON-CL4-2026-01-MAT-PROD-04: Optimise the usage of resources in a circular economy (RIA) (Processes4Planet and Clean Steel partnerships)

RIA

64.00

5.00 to 8.00

9

HORIZON-CL4-2026-01-MAT-PROD-05: Circular innovative advanced materials: facilitating the transition from design to markets (RIA) (Innovative Advanced Materials for the EU and Made in Europe partnerships)

RIA

37.00

5.00 to 6.50

7

HORIZON-CL4-2026-01-MAT-PROD-31: Efficient capture / purification / utilisation of CO2 for the production of competitive products (RIA) (Processes4Planet partnership)

RIA

43.80

5.00 to 7.00

7

HORIZON-CL4-2026-01-MAT-PROD-41: Enhancing industry-academia knowledge exchange in Social Sciences and Humanities (SSH) (CSA)

CSA

2.00

Around 1.00

2

HORIZON-CL4-2026-01-MAT-PROD-44: Attracting management talent for capacity building for Technology Infrastructures staff members (CSA)

CSA

2.50

Around 3.00

1

HORIZON-CL4-2026-01-MAT-PROD-45: Pilot access schemes to Technology Infrastructures for European startups, scaleups and innovative SMEs (CSA)

CSA

5.00

1.50 to 2.50

2

HORIZON-CL4-2026-01-MAT-PROD-46: Mapping and service finder for Technology Infrastructures (CSA)

CSA

2.00

Around 2.00

1

HORIZON-CL4-2026-01-MAT-PROD-48: ‘Proof of market’ to improve valorisation and commercialisation of Horizon generated R&I results (IA)

IA

5.00

Around 0.20

25

Raw Materials

HORIZON-CL4-2026-01-MAT-PROD-11: Innovative technologies and tools for exploration and data modelling of raw materials (RIA)

RIA

18.50

5.00 to 7.00

3

HORIZON-CL4-2026-01-MAT-PROD-12: Technologies for innovative extraction of critical raw materials (RIA)

RIA

19.00

5.00 to 7.00

3

HORIZON-CL4-2026-01-MAT-PROD-13: Monitoring of secondary raw materials (CSA)

CSA

4.00

Around 4.00

1

HORIZON-CL4-2026-01-MAT-PROD-14: Improving availability of secondary raw materials through recycling (IA)

IA

28.00

Around 7.50

4

Overall indicative budget

319.60

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - INDUSTRY-two-stage

HORIZON-CL4-2026-02-two-stage

Overview of this call 3

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 4

Indicative number of projects expected to be funded

2027

Opening: 16 Dec 2025

Deadline(s): 17 Mar 2026 (First Stage), 13 Oct 2026 (Second Stage)

Destination: Leadership in materials and production for Europe

HORIZON-CL4-2026-02-MAT-PROD-21-two-stage: Development of safe and sustainable alternatives to substances of concern (IA)

IA

38.00

6.00 to 7.50

6

Destination: Achieving open strategic autonomy in digital and emerging enabling technologies

HORIZON-CL4-2026-02-DIGITAL-EMERGING-51-two-stage: AI improved advanced manufacturing and production processes in factories (RIA) (Made in Europe and AI, Data and Robotics partnerships)

RIA

30.00

4.00 to 6.00

5

HORIZON-CL4-2026-02-DIGITAL-EMERGING-53-two-stage: Innovative AI methods and technologies for the process industries (RIA) (Processes4Planet and AI, Data and Robotics partnerships)

RIA

30.00

4.00 to 6.00

6

Overall indicative budget

98.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - INDUSTRY

HORIZON-CL4-2027-01

Overview of this call 5

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 6

Indicative number of projects expected to be funded

2027

Opening: 22 Sep 2026

Deadline(s): 02 Feb 2027

Destination: Leadership in materials and production for Europe

HORIZON-CL4-2027-01-MAT-PROD-22: Innovative advanced materials and new production processes – reducing dependencies on Critical and Strategic Raw Materials (IA) (Innovative Advanced Materials for the EU and Processes4Planet partnerships)

IA

36.00

6.00 to 7.50

6

HORIZON-CL4-2027-01-MAT-PROD-02: Advanced manufacturing for key products (IA) (Made in Europe partnership)

IA

36.00

6.00 to 8.00

6

HORIZON-CL4-2027-01-MAT-PROD-03: Factory processes and automation for de- and re-manufacturing (RIA) (Made in Europe partnership)

RIA

36.00

5.00 to 6.50

6

HORIZON-CL4-2027-01-MAT-PROD-06: Circular innovative advanced materials: facilitating the transition from design to markets (RIA) (Innovative Advanced Materials for the EU and Made in Europe partnerships)

RIA

36.00

5.00 to 6.50

7

HORIZON-CL4-2027-01-MAT-PROD-08: Textile circularity through advanced processing and manufacturing technologies and system approaches (IA) (Textiles for the Future partnership)

IA

16.00

4.00 to 6.00

3

HORIZON-CL4-2027-01-MAT-PROD-42: Unlocking the potential of academic intellectual assets for industry, SMEs and startups (CSA)

CSA

2.00

Around 1.00

2

HORIZON-CL4-2027-01-MAT-PROD-47: Pilot access schemes to Technology Infrastructures for European startups, scaleups and innovative SMEs (CSA)

CSA

5.00

1.50 to 2.50

2

HORIZON-CL4-2027-01-MAT-PROD-49: ‘Proof of market’ to improve valorisation and commercialisation of Horizon generated R&I results (IA)

IA

5.00

Around 0.20

25

Raw Materials

HORIZON-CL4-2027-01-MAT-PROD-16: Technologies for innovative processing of raw materials (IA)

IA

49.00

10.00 to 12.50

4

HORIZON-CL4-2027-01-MAT-PROD-17: Expert network on Critical raw materials (CSA)

CSA

3.00

Around 3.00

1

Overall indicative budget

224.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - INDUSTRY-two-stage

HORIZON-CL4-2027-02-two-stage

Overview of this call 7

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 8

Indicative number of projects expected to be funded

2027

Opening: 22 Sep 2026

Deadline(s): 02 Feb 2027 (First Stage), 02 Sep 2027 (Second Stage)

Destination: Leadership in materials and production for Europe

HORIZON-CL4-2027-02-MAT-PROD-32-two-stage: Efficient energy input from renewable sources and energy management in the process industries (IA) (Processes4Planet and Innovative Advanced Materials for the EU partnerships)

RIA

52.50

7.00 to 9.00

6

Destination: Achieving open strategic autonomy in digital and emerging enabling technologies

HORIZON-CL4-2027-02-DIGITAL-EMERGING-52-two-stage: New approaches for Human/AI collaboration for the workforce of the future (RIA) (Made in Europe and AI, Data and Robotics partnerships)

RIA

30.00

4.00 to 6.00

5

Overall indicative budget

82.50

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - INDUSTRY-FTRI

HORIZON-CL4-2027-06

Overview of this call 9

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 10

Indicative number of projects expected to be funded

2027

Opening: 22 Sep 2026

Deadline(s): 02 Feb 2027

Destination: Leadership in materials and production for Europe

HORIZON-CL4-2027-01-MAT-PROD-61: Fast Track to Research and Innovation for breakthroughs in industrial technologies (Research and Innovation Action)

RIA

20.00

0.00 to 2.50

8

HORIZON-CL4-2027-01-MAT-PROD-62: Fast Track to Innovation for breakthroughs in the Chemical Industry Action Plan (Research and Innovation Action)

RIA

15.00

0.00 to 2.50

6

Overall indicative budget

35.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - SPACE

HORIZON-CL4-2026-03

Overview of this call 11

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 12

Indicative number of projects expected to be funded

2026

Opening: 10 Mar 2026

Deadline(s): 03 Sep 2026

Destination: Open Strategic Autonomy in Developing, Deploying and Using Global Space-Based Infrastructure, Services, Applications and Data

HORIZON-CL4-2026-SPACE-03-11: Reinforcing EU autonomous access to space through EU-based spaceports

IA

22.59

10.00 to 15.00

2

HORIZON-CL4-2026-SPACE-03-31: Digital enablers and building-blocks for Earth Observation and Satellite telecommunication for Space solutions (Space Partnership)

RIA

12.00

3.00 to 6.00

3

HORIZON-CL4-2026-SPACE-03-32: Preparing demonstration missions for Earth Observation and Satellite telecommunication for Space solutions (Space Partnership)

IA

26.00

5.00 to 10.00

4

HORIZON-CL4-2026-SPACE-03-61: Scientific analysis and exploitation of space data

RIA

3.92

1.50 to 2.50

2

HORIZON-CL4-2026-SPACE-03-81: Space critical EEE components for EU non-dependence – Radiation Hard FPGA on 7nm

RIA

12.74

12.00 to 13.00

1

HORIZON-CL4-2026-SPACE-03-82: Space critical EEE components for EU non-dependence – GaN MMICs mm-Wave Foundations (Phase A): Development and Industrialization of Semi-insulating SiC Substrate Capabilities

RIA

6.86

6.00 to 7.00

1

HORIZON-CL4-2026-SPACE-03-85: Critical Facilities Serving Space EEE components for EU non-dependence – High and Very High Energy Irradiation Test Facility Market Deployment

IA

3.92

3.00 to 4.00

1

HORIZON-CL4-2026-SPACE-03-86: Space critical Equipment for EU non-dependence – Space Refuelling Interface

RIA

2.94

2.00 to 3.00

1

Overall indicative budget

90.97

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - SPACE

HORIZON-CL4-2027-03

Overview of this call 13

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 14

Indicative number of projects expected to be funded

2027

Opening: 09 Mar 2027

Deadline(s): 02 Sep 2027

Destination: Open Strategic Autonomy in Developing, Deploying and Using Global Space-Based Infrastructure, Services, Applications and Data

HORIZON-CL4-2027-SPACE-03-12: Digital solutions for autonomy for space transportation systems, design and simulation tools - Digital enablers and building blocks (Space Partnership)

IA

5.00

2.00 to 3.00

2

HORIZON-CL4-2027-SPACE-03-21: ISOS4I Pilot Mission Integrated Ground Test and consolidation of space-compatible USI solutions

RIA

0.98

0.80 to 1.00

1

HORIZON-CL4-2027-SPACE-03-33: Digital enablers and building blocks for collaborative Earth Observation and Satellite telecommunications for Space solutions (Space Partnership)

RIA

4.00

1.50 to 3.00

2

HORIZON-CL4-2027-SPACE-03-34: Preparing demonstration missions for collaborative Earth Observation and Satellite telecommunication for Space solutions (Space Partnership)

IA

26.00

5.00 to 10.00

4

HORIZON-CL4-2027-SPACE-03-83: Space critical EEE components for EU non-dependence

RIA

0.49

0.25 to 0.30

1

HORIZON-CL4-2027-SPACE-03-84: Space critical equipment for EU non-dependence

RIA

0.49

0.25 to 0.30

1

HORIZON-CL4-2027-SPACE-03-71: Quantum Space Gravimetry topic

RIA

29.20

14.00 to 15.00

2

Overall indicative budget

66.16

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - DIGITAL

HORIZON-CL4-2026-04

Overview of this call 15

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 16

Indicative number of projects expected to be funded

2026

Opening: 15 Jan 2026

Deadline(s): 15 Apr 2026

Destination: Developing an agile and secure single market and infrastructure for data-services and trustworthy artificial intelligence services

HORIZON-CL4-2026-04-DATA-02: Open Internet Stack Sovereign Solutions (RIA)

RIA

20.50

7.00 to 10.25

2

HORIZON-CL4-2026-04-DATA-03: Open Internet Stack Support for Scale (CSA)

CSA

4.00

Around 4.00

1

HORIZON-CL4-2026-04-DATA-06: Efficient and compliant access to and use of data (IA) (AI, Data and Robotics partnership)

IA

46.50

11.50 to 23.50

3

Destination: Achieving open strategic autonomy in digital and emerging enabling technologies

HORIZON-CL4-2026-04-DIGITAL-EMERGING-01: Apply AI: Pilot of the “Science for AI” Pillar of RAISE (“Resource for AI science in Europe”) (RIA)

RIA

17.00

Around 17.00

1

HORIZON-CL4-2026-04-DIGITAL-EMERGING-19: Challenge-Driven GenAI4EU Booster in Apply AI prioritised sectors (RIA) (AI/Data/Robotics Partnership)

RIA

45.00

Around 15.00

3

HORIZON-CL4-2026-04-DIGITAL-EMERGING-08: Apply AI: Robotics for Manufacturing: Advancing Core Skills through Technical Challenges (RIA) (Partnership in AI, Data and Robotics)

RIA

18.00

Around 18.00

1

HORIZON-CL4-2026-04-DIGITAL-EMERGING-09: Advanced Local Digital Twins using AI for Early Warning and Preparedness (IA)

IA

6.00

Around 6.00

1

HORIZON-CL4-2026-04-DIGITAL-EMERGING-11: Grand Challenge on Quantum Sensors for Inertial Navigation

CSA

2.00

Around 0.50

3

HORIZON-CL4-2026-04-DIGITAL-EMERGING-12: Standards for Quantum Technologies – Coordination and Support Action (CSA)

CSA

1.00

Around 1.00

1

HORIZON-CL4-2026-04-DIGITAL-EMERGING-18: Large-Scale Photonic Quantum Computing Platform Technologies (RIA)

RIA

10.00

Around 10.00

1

HORIZON-CL4-2026-04-DIGITAL-EMERGING-14: Networking and Future Photonics Strategy (CSA) (Photonics Partnership)

CSA

3.00

Around 3.00

1

HORIZON-CL4-2026-04-DIGITAL-EMERGING-15: Strengthening the cooperation of semiconductor-intensive EU regions (CSA)

CSA

1.00

Around 1.00

1

HORIZON-CL4-2026-04-DIGITAL-EMERGING-17: Fostering 2-Dimensional Materials (2DM) based emerging and enabling technologies (CSA)

CSA

1.00

Around 1.00

1

Destination: Digital and industrial technologies driving human-centric innovation

HORIZON-CL4-2026-04-HUMAN-01: Developing and demonstrating core technologies for Virtual Worlds and Web 4.0 (IA) (Virtual worlds Partnership)

IA

30.00

4.00 to 5.00

7

HORIZON-CL4-2026-04-HUMAN-02: Web 4.0 architectural framework and Open Internet Stack applications for virtual worlds (RIA)

RIA

16.80

2.80 to 8.40

3

Overall indicative budget

221.80

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - DIGITAL

HORIZON-CL4-2027-04

Overview of this call 17

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 18

Indicative number of projects expected to be funded

2027

Opening: 17 Nov 2026

Deadline(s): 18 Mar 2027

Destination: Developing an agile and secure single market and infrastructure for data-services and trustworthy artificial intelligence services

HORIZON-CL4-2027-04-DATA-08: Demand-side 3C pilot demonstrators on converged Telco Edge Cloud Infrastructure (IA)

IA

38.00

Around 19.00

2

HORIZON-CL4-2027-04-DATA-03: New approaches for decentralized, federated and sustainable AI data processing (RIA)

RIA

35.00

Around 17.50

2

HORIZON-CL4-2027-04-DATA-09: Energy efficiency and sustainability of AI data processing in Data Centres (IA)

IA

39.00

Around 10.00

3

Destination: Achieving open strategic autonomy in digital and emerging enabling technologies

HORIZON-CL4-2027-04-DIGITAL-EMERGING-11: EU Frontier AI Initiative: Developing frontier AI solutions that are safe and computationally efficient within Apply AI (RIA)

RIA

44.00

Around 44.00

1

HORIZON-CL4-2027-04-DIGITAL-EMERGING-04: Apply AI: Challenge-Driven AI Innovation Booster in Apply AI prioritised sectors (RIA) (Partnership in AI, Data and Robotics)

RIA

42.00

Around 14.00

3

HORIZON-CL4-2027-04-DIGITAL-EMERGING-05: Apply AI: AI-Driven Robotics for Industry: Enabling System Integration and Adoption (IA) (Partnership in AI, Data and Robotics)

IA

18.00

Around 18.00

1

HORIZON-CL4-2027-04-DIGITAL-EMERGING-06: International cooperation in AI (IA)

IA

3.00

Around 1.50

2

HORIZON-CL4-2027-04-DIGITAL-EMERGING-10: Horizon scanning and foresight in future enabling digital technologies (CSA)

CSA

4.00

Around 4.00

1

Destination: Digital and industrial technologies driving human-centric innovation

HORIZON-CL4-2027-04-HUMAN-01: Advanced and Innovative hardware components for Virtual Worlds (RIA) (Virtual Worlds Partnership)

RIA

39.00

4.80 to 5.60

8

HORIZON-CL4-2027-04-HUMAN-02: Create a thriving and competitive Virtual Worlds and Web 4.0 ecosystem (CSA) (Virtual Worlds Partnership)

CSA

3.00

Around 3.00

1

HORIZON-CL4-2027-04-HUMAN-07: Facilitate the engagement of European stakeholders in international digital standardisation (CSA)

CSA

7.00

Around 7.00

1

Overall indicative budget

272.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - DIGITAL

HORIZON-CL4-2026-05

Overview of this call 19

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 20

Indicative number of projects expected to be funded

2026

Opening: 15 Jan 2026

Deadline(s): 15 Apr 2026

Raw Materials

HORIZON-CL4-2026-05-MAT-PROD-25: New or enhanced Innovative Advanced Materials (IAM) enabled sensing functionality (RIA)

RIA

22.50

Around 7.50

3

Destination: Achieving open strategic autonomy in digital and emerging enabling technologies

HORIZON-CL4-2026-05-DIGITAL-EMERGING-02: Next-Generation AI Agents for Real-World Applications in the Apply AI sectors (RIA) (Partnership in AI, Data and Robotics)

RIA

38.00

Around 19.00

2

HORIZON-CL4-2026-05-DIGITAL-EMERGING-03: Apply AI: Next-Generation Agile and Intelligent Robotics Platforms for Industrial and Service Applications (Partnership in AI, Data and Robotics) (RIA)

RIA

25.00

12.00 to 13.00

2

Overall indicative budget

85.50

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Call - DIGITAL

HORIZON-CL4-2027-05

Overview of this call 21

Proposals are invited against the following Destinations and topic(s):

Topics

Type of Action

Budgets (EUR million)

Expected EU contribution per project (EUR million) 22

Indicative number of projects expected to be funded

2027

Opening: 17 Nov 2026

Deadline(s): 18 Mar 2027

Destination: Achieving open strategic autonomy in digital and emerging enabling technologies

HORIZON-CL4-2027-05-DIGITAL-EMERGING-03: Advanced integrated photonic devices for extended features and ultra-low power consumption (RIA) (Photonics Partnership)

RIA

25.00

3.00 to 5.00

6

Overall indicative budget

25.00

General conditions relating to this call

Admissibility conditions

The conditions are described in General Annex A.

Eligibility conditions

The conditions are described in General Annex B.

Financial and operational capacity and exclusion

The criteria are described in General Annex C.

Award criteria

The criteria are described in General Annex D.

Documents

The documents are described in General Annex E.

Procedure

The procedure is described in General Annex F.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G.

Destinations

Destination: Leadership in materials and production for Europe

This Destination brings together the research and innovation for a globally competitive European industry through the twin green and digital transition, and the availability, development, use, reuse and disposal of chemicals, advanced materials and critical raw materials.

The Competitiveness Compass announces initiatives that should be served directly by industry-linked activities in Cluster 4, through new, focused R&I activities, but also through the activities supported up to now:

1.Clean Industrial Deal adopted in February 2025;

2.Critical Raw Materials Act;

3.Advanced Materials Communication and future Advanced Materials Act planned for 2026;

4.Future Circular Economy Act planned for 2026;

5.Steel and Metals Action Plan adopted in March 2025;

6.European Chemicals Industry Action Plan adopted in July 2025;

7.Industrial action plan for the European automotive sector adopted in March 2025; and

8.Strategy on research and technology infrastructures, with regard to technology infrastructures and the valorisation of knowledge.

In order to better translate these policy priorities into actions, to integrate the latest inputs from the partnerships, and to achieve synergies, this Work Programme part adopts a more integrated approach. The headings used under the two industry-focused destinations in previous work programmes, reflecting different partnerships and industrial sectors, are replaced by new headings making strongly interconnected contributions to the corresponding expected impacts in the Strategic Plan 2025-27, on green and digital transition and on autonomy in raw and advanced materials.

The new approach takes into account R&I investments under previous work programmes and intends to introduce more synergies with other pillars (notably the European Innovation Council under Pillar III) as well as with Cluster 5. Topics in this Work Programme increasingly combine the priorities of different partnerships to enable synergies, e.g. with the Investment fund, while continuing to address the particularities of each partnership. The development of new and cross-cutting technologies will help transform existing value chains and create new ones.

In addition to this Work Programme part, Cluster 4 participates in a horizontal Clean Industrial Deal Call, aiming to increase the competitiveness and decarbonisation of industry. The initiative will allow Horizon Europe beneficiaries to feed the EU deployment pipeline with R&I solutions close to market uptake and deployment, whilst also supporting the development by 2035 of a new batch of industry-led demonstrators designed for higher market readiness.

In addition to decarbonisation, manufacturing and energy-intensive industries need to embrace the circular economy as a key pillar in the design of their value chains. This will be fundamental to their resource efficiency (in terms of materials, energy and water). Particularly important in this context is the upcycling of secondary raw materials and waste; de- and re-manufacturing; and the development of sustainable and resource-efficient industrial processes

This Work Programme continues to promote across the calls the application of Safe and Sustainable by Design approach incorporating early and parallel considerations of innovation design choices on impacts on health, environment, climate and other sustainability parameters as a way of achieving stated policy objectives and fostering quick market uptake.

Where projects are asked to contribute to the development of safe and sustainable products, projects should take into account safety concerns for consumers as well as the organisational health and safety aspects for industrial workers.

Finally, to support start-ups and scale-ups, this Work Programme includes support for technology infrastructures and valorisation of knowledge.

Business cases and exploitation strategies for industrialisation:

This section applies only to those topics in this Destination, for which proposals should demonstrate the expected outcomes by including a business case and exploitation strategy for industrialisation.

A business case and a credible initial exploitation strategy are essential components in the ultimate success of an industry-based project, as well as its prospects to attract further investments for deployment. They will both be decisive factors under the impact criterion, and proposers are encouraged to use the extended page limit to present a carefully considered business case and exploitation strategy, backed by the management of the companies involved.

The business case should demonstrate the expected impact of the proposal in terms of enhanced market opportunities for the participants and deployment in the EU, in the short to medium term. It should describe the targeted market(s); estimated market size in the EU and globally; user and customer needs; and demonstrate that the solutions will match the market and user needs in a cost-effective manner; and describe the expected market position and competitive advantage.

The exploitation strategy should identify obstacles, requirements and necessary actions involved in reaching higher TRLs (Technology Readiness Levels), for example: securing the required investments, including through possible synergies with other programmes; accessing the required skills; matching value chains; enhancing product robustness; securing industrial integrators; and user acceptance.

For TRLs 6 and 7, a credible strategy to achieve future full-scale deployment in the EU is expected, indicating the intentions of the industrial partners after the end of the project.

Where relevant, in the context of skills, it is recommended to develop training material to endow workers with the right skillset in order to support the uptake and deployment of new innovative products, services, and processes developed in the different projects. This material should be tested and be scalable, and can potentially be up-scaled through the European Social Fund Plus (ESF+). This will help the European labour force to close the skill gaps in the relevant sectors and occupational groups and improve employment and social levels across the EU and associated countries.

Where projects are asked to contribute to the development of safe and sustainable products, projects should take into account safety concerns for consumers and the organisational health and safety aspects for industrial workers.

For topics in this destination, consortia (if selected for funding) will be called upon to cooperate with the relevant parts of the Joint Research Centre (JRC), in order to inform the next stages of EU technology and innovation policies.

1.INnovation Centre for Industrial Transformation and Emissions (INCITE) ( https://innovation-centre-for-industrial-transformation.ec.europa.eu/ ).

2.The Energy and Industry Geography Lab: EIGL ( https://energy-industry-geolab.jrc.ec.europa.eu/ ).

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Sustainable Advanced Materials, Raw Materials and Chemicals

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-02-MAT-PROD-21-two-stage: Development of safe and sustainable alternatives to substances of concern (IA)

Call: INDUSTRY-two-stage

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 7.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 38.00 million.

Type of Action

Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

In order to include a business case and exploitation strategy, as outlined in the introduction to Destination 'Leadership in materials and production for Europe', the page limit in part B of the General Annexes is exceptionally extended by 3 pages (for second-stage proposals).

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.Make safer and more sustainable alternatives to substances of concern available to the industries offering products with targeted performances and supporting their competitiveness,

2.Speeding up the innovation cycle within a value chain important for European industry;

3.Enhancing competitiveness of the industries by reducing regulatory and operational costs, while making supply chains more secure;

4.Production processes, chemicals, materials and products that are inherently safer and more sustainable for a clean and autonomous economy; and

5.Demonstrating how the safe and sustainable by design (SSbD) chemicals and materials framework can guide innovation and encourage innovators to minimise the use of substances of concern, reducing negative impacts on human health, climate and ecosystems.

Scope: The focus of this topic is on alternatives for the substitution of substances of concern (SoCs) as defined in the Ecodesign for Sustainable Product regulation 23 . The design and development of these alternatives should lead to an innovation cycle covering their (re)design, development, production processes, and integration into products in manufacturing.

The scope includes necessary developments of related processes and technologies to ensure alignment with and integration in industrial manufacturing facilitating uptake of the develop alternatives. If relevant, challenges for the adaption of existing production lines should be identified and solutions proposed.

Proposals should develop new chemical substances, innovative advanced materials or technologies to replace existing SoCs in one of the following areas: energy, mobility, construction, electronics, technical textiles as well as medical devices.

Proposals should demonstrate that the proposed alternative has a clear use case, market and potential to grow. The substitution barriers for the selected applications should be identified and effective mechanisms to maximise substitution within the targeted value chains proposed.

Proposals should demonstrate that SSbD framework 24 will be applied throughout the innovation process, showing that safety and sustainability principles are actively integrated and influence decision-making in a transparent and traceable way, and ensure that the data generated within the proposal may be shared with the Common Data Platform for Chemicals. The new alternatives to be developed should meet the technical functions required in the specific applications while aligning their innovation process decision making with such framework.

Proposals are encouraged to cooperate with relevant projects and should contribute to and cooperate with the EU Innovation and Substitution Hub(s). Proposals should allocate the necessary resources to the proposed activities.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

Proposals could consider involving the European Commission's Joint Research Centre (JRC), whose contribution could add value to the operationalisation of the SSbD framework.

HORIZON-CL4-2027-01-MAT-PROD-22: Innovative advanced materials and new production processes – reducing dependencies on Critical and Strategic Raw Materials (IA) (Innovative Advanced Materials for the EU and Processes4Planet partnerships)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 7.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 36.00 million.

Type of Action

Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

To increase EU resilience in raw materials supply chains and thus reduce the serious risk to the Union's strategic assets, economic and societal interests, autonomy and security associated with the current EU reliance on a few third countries for critical raw materials, by increasing sustainable and responsible sourcing of primary and secondary raw materials necessary to enable the green and digital transition and in alignment with the objectives of the Critical Raw Materials Act 25 , participation in this topic is limited to legal entities established in Member States, associated countries, OECD countries, African Union Member States, MERCOSUR, CARIFORUM, Andean Community and countries with which the EU has concluded strategic partnerships on raw materials 26 as well as trade agreements (or association/economic partnership or equivalent agreements, including the new Clean Trade and Investment Partnerships) containing raw materials cooperation provisions (i.e. Energy and Raw materials chapters) 27 . The choice of these countries was made taking into consideration the development of strategic international partnerships on raw materials and avoidance of reinforcing existing over-dependencies, as well as the importance of involving partners committed to pursuing open trade in such materials.

Proposals including legal entities which are not established in the countries that fall under the criteria above will be ineligible.

For the duly justified and exceptional reasons listed above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or a non-eligible country entity, shall not participate in the action.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.Reducing dependencies of critical and strategic raw materials through partial or total substitution by safe and sustainable innovative advanced materials and/or via more efficient use of critical and strategic raw materials in production processes;

2.Speeding up the innovation cycle within value chain(s) important for European industry;

3.Enhancing competitiveness of the industries and operational costs, while making supply chains more secure;

4.New or improved production processes, innovative advanced materials and products that are safer and more sustainable, supporting a clean and autonomous economy; and

5.Demonstrating how the safe and sustainable by design (SSbD) chemicals and materials framework can guide innovation.

Scope: The focus of this topic is on alternatives for the substitution or more efficient use of critical and strategic raw materials 28 . The design and development of innovative advanced materials (IAMs) and processes should lead to an innovation cycle covering the (re)design of materials and production processes, and the integration of IAMs into products.

Proposals should develop IAMs or process technologies to replace or reduce the use of critical and strategic raw materials in strategic areas and sectors such as energy, mobility, construction, electronics, medical devices or chemical industries.

Proposals should address one or several of the following approaches:

1.Design, development and production with targets on performance, safety and sustainability of IAMs substituting or making a more efficient use of critical and strategic raw materials.

2.Innovative industrial processes for the reduction of the use of critical and strategic raw materials focussed on optimizing process safety, sustainability, flexibility, scalability, cost-efficiency.

3.Co-development strategies for IAMs and industrial processes. These strategies should demonstrate the value of co-development through specific use cases while maintaining broad relevance across various materials and process types.

Proposals should demonstrate clear use case(s), market and potential to grow. The substitution barriers for the selected applications should be identified and a driving mechanism for a maximal substitution in the targeted value chains proposed.

The scope includes necessary adaptations of related processes and technologies to ensure alignment with and integration in industrial manufacturing in order to facilitate the uptake of the developed solutions. If relevant, challenges for the adaption of existing production lines should be identified and solutions proposed.

Proposals should demonstrate that SSbD framework 29 will be applied throughout the innovation process, showing that safety and sustainability principles are actively integrated and influence decision-making in a transparent and traceable way, and ensure that the data generated within the proposal may be shared with the Common Data Platform for Chemicals. The new alternatives to be developed should meet the technical functions required in the specific applications while aligning their innovation process decision making with such framework.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

Proposals are encouraged to cooperate with relevant projects. Where relevant, proposals should actively contribute to and cooperate with the EU Innovation and Substitution Hub(s) 30 . Proposals should allocate the necessary resources to the proposed activities

This topic implements the co-programmed European partnerships Innovative Advanced Materials for the EU (IAM4EU) and Processes4Planet.

HORIZON-CL4-2026-01-MAT-PROD-23: Accelerating the discovery and development of chemicals and innovative advanced materials through digitalisation and artificial intelligence (IA) (Innovative Advanced Materials for the EU partnership)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 13.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 50.00 million.

Type of Action

Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.Accelerating the discovery and development process for innovative advanced materials and chemicals through digital tools developed in Europe;

2.Innovation workflows which include design of experiment and/or design of simulation

3.Supporting the operationalisation of the SSbD framework;

4.Making a step change in the risk assessment of chemicals and advanced materials in Europe.

Scope: Proposals should accelerate the pathway to market of new substances (chemicals or advanced materials) with superior or novel functionalities. This can be achieved with novel tools or proofs of concept using digital methods to accelerate development of new materials and demonstration of their properties. Where possible this should explore collaboration with other initiatives such as the Materials Commons for Europe or DIGIPASS, contributing data, modelling, digital tools applicable to the design, development, production, manufacturing, use and end of life phases, which connect to repeatable workflows. These workflows and tools may include the use of artificial intelligence as well as self-driving labs and their interconnection and design of experiment/design of simulation methods. They should also drive innovation in risk assessment, new test methods and support and facilitate the operationalisation and use of the SSbD framework 31 . Projects should include demonstrators which help to validate the materials development in realistic conditions.

By doing so, new innovative advanced materials (IAMs) with superior or novel functionalities and alternatives to substances of concern should be developed more rapidly in Europe. In addition, digital feedback loops ranging from requirements and information from production processes and scale-up, to manufacturing and integration into products, should be developed to accelerate market uptake. Innovative digital tools to speed up risk assessment and thereby market access of chemicals and advanced materials may also be addressed.

Interoperable workflows based on shared standards and dedicated ontologies, in particular through collaboration with the Materials Commons for Europe, should help to reduce the cost of the digital transition for industry with respect to circularity and safe and sustainable by design, e.g. by reducing the risk for adopters and vendors, and through modular tools that can be extended to new application domains without a major redesign. Tools should foster workflows in that ensure high-quality, well-structured and documented primary FAIR data and FAIR digital tools and workflows, enabling the re-use and/or streamlining of large data sets, facilitating academic and industrial collaborations and integrating AI and other digital technologies. Synergies with the SSbD toolboxes can also be foreseen including the adaptation and validation 32 of the test methods for advanced materials. Proposals could also facilitate the generation of relevant data and where relevant sharing of data with the Common Data Platform for Chemicals. Where relevant, proposals should actively contribute to and cooperate with the EU Innovation and Substitution Hub(s). Proposals should allocate the necessary resources to the proposed activities.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

Proposals could consider the involvement of the European Commission's Joint Research Centre (JRC), whose contribution could consist of added value to the operationalisation of the SSbD framework.

This topic implements the co-programmed European Partnership Innovative Advanced Materials for the EU (IAM4EU).

HORIZON-CL4-2026-01-MAT-PROD-24: Cooperation on innovative advanced materials with Japan (CSA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 0.80 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 0.80 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 33 .

Expected Outcome:

1.Cooperation with Japan in the field of innovative advanced materials is strengthened.

Scope: Advanced materials are an important factor for the competitiveness of Japanese and European industries and are a crucial building block for strengthening resilience and open strategic autonomy, including through international collaboration. Against this background, the European Commission and the Japanese Ministry of Science, Technology and Innovation Policy, have in April 2024 announced the launch of the EU-Japan Enhanced Dialogue 34 on Advanced Materials. This builds on the success of EU-Japan collaboration in R&I in material sciences. It aims to create a platform for sharing information on policy developments and exploring the opportunities to pursue collaborative research in the areas of mutual interest.

As part of the EU-Japan Enhanced Dialogue on Advanced Materials and taking into account the Communication on Advanced Materials for Industrial Leadership 35 , the purpose of this action is to enable European researchers in innovative advanced materials from Member States and Associated Countries to make research visits to related Japanese institutions. Proposals should aim to provide travel grants strengthening collaboration in relevant ongoing research activities in Europe on the topic of advanced materials with applications to either mobility, energy, construction, electronics or medical devices. Proposals should ensure a wide geographical coverage of the grants in Member States and Associated Countries. They should aim at visits to research groups at Japanese organisations with complementary activities for up to one month duration. Such travel grants should build on collaborations with Japanese organisations that are willing to receive such a visits. Proposals can either support the initiation of new collaborations, or existing collaborations.

Fast-tracking Circularity

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-01-MAT-PROD-01: Advanced manufacturing for key products (IA) (Made in Europe partnership)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 38.00 million.

Type of Action

Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering also the automotive industry, grants will be awarded to applications not only in order of ranking but at least also to one proposal that is the highest ranked with focus on the automotive industry, provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.Advanced manufacturing technology and machinery becomes available in Europe for the manufacturing of key and high-performance products;

2.Where relevant, production becomes increasingly circular through the reuse of secondary raw materials; and/or innovative advanced materials are incorporated in manufactured products, leading to better performance and quality;

3.Resource efficiency in terms of materials and energy is increased significantly; and

4.Circularity, productivity and competitiveness are increased, and hence resilience of European industry is enhanced.

Scope: This topic addresses technologies and machinery for advanced manufacturing, focusing on manufacturing excellence and on increasing circularity, including through the better use of innovative advanced materials and secondary raw materials. The focus is on key manufactured components and products that are competitive and have enhanced performance, and contribute to Europe’s technological leadership in manufacturing, but which are at risk of being lost to Europe or rely on raw materials or parts whose supply is mostly coming from outside Europe.

Proposals should develop technologies and machinery to enable the manufacturing of these components with a minimal use of critical raw materials [reference to overall targets] or imported materials. This includes an increased use of secondary raw materials or biobased materials or revalorised components.

Where appropriate to enhance performance and quality, proposals should target the use of innovative advanced materials (such as lightweight, functionalised or self-healing materials). In this case, the development of the advanced materials should not be the main focus of proposals, nevertheless the necessary steps to adapt such innovative advanced materials to the needs of the manufacturing application should be included. These can include digital twins for materials as well as SSbD-design steps.

Examples of advanced manufacturing technologies and machinery include, but are not restricted to:

1.Innovative additive manufacturing;

2.Hybrid manufacturing (additive, subtractive);

3.Photonics;

4.Advanced joining technologies;

5.Polymer composite manufacturing;

6.Advanced technologies for surface treatment and structuring, to tailor surface properties for specific applications;

7.Manufacturing of components with lightweight materials; and

8.In-line testing.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

The portfolio approach will be used, to ensure that at least one proposal focusing on the automotive industry is funded. However, the production of batteries is not within the scope of this topic. 36

International cooperation is encouraged, especially with Japan or Taiwan.

This topic implements the co-programmed European Partnership Made in Europe.

HORIZON-CL4-2027-01-MAT-PROD-02: Advanced manufacturing for key products (IA) (Made in Europe partnership)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 6.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 36.00 million.

Type of Action

Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.Advanced manufacturing technology and machinery becomes available in Europe for the manufacturing of key and high-performance products;

2.Where relevant, production becomes increasingly circular through the reuse of secondary raw materials; and/or innovative advanced materials are incorporated in manufactured products, leading to better performance and quality;

3.Resource efficiency in terms of materials and energy is increased significantly; and

4.Circularity, productivity and competitiveness are increased, and hence resilience of European industry is enhanced.

Scope: This topic addresses technologies and machinery for advanced manufacturing, focusing on manufacturing excellence and on increasing circularity, including through the better use of innovative advanced materials and secondary raw materials. The focus is on key manufactured components and products that are competitive and have enhanced performance, and contribute to Europe’s technological leadership in manufacturing, but which are at risk of being lost to Europe or rely on raw materials or parts whose supply is mostly coming from outside Europe.

Proposals should develop technologies and machinery to enable the manufacturing of these components with a minimal use of critical raw materials [reference to overall targets] or imported materials. This includes an increased use of secondary raw materials or biobased materials or revalorised components.

Where appropriate to enhance performance and quality, proposals should target the use of innovative advanced materials (such as lightweight, functionalised or self-healing materials). In this case, the development of the advanced materials should not be the main focus of proposals, nevertheless the necessary steps to adapt such innovative advanced materials to the needs of the manufacturing application should be included. These can include digital twins for materials as well as SSbD-design steps.

Examples of advanced manufacturing technologies and machinery include, but are not restricted to:

1.Innovative additive manufacturing;

2.Hybrid manufacturing (additive, subtractive);

3.Photonics;

4.Advanced joining technologies;

5.Polymer composite manufacturing;

6.Advanced technologies for surface treatment and structuring, to tailor surface properties for specific applications;

7.Manufacturing of components with lightweight materials; and

8.In-line testing.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

Applications in the automotive industry may be considered. However, the production of batteries is not within the scope of this topic. 37

International cooperation is encouraged, especially with Japan or Taiwan.

This topic implements the co-programmed European Partnership Made in Europe.

HORIZON-CL4-2027-01-MAT-PROD-03: Factory processes and automation for de- and re-manufacturing (RIA) (Made in Europe partnership)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 6.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 36.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Technology Readiness Level

Activities are expected to start at TRL 4-5 and achieve TRL 6 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 38 .

Expected Outcome:

1.A viable industrial ecosystem for circularity in manufacturing industries emerges, enhancing both circularity and resilience;

2.De-manufacturing technologies and practices become available, making decisive contributions to a European remanufacturing industry and market;

3.Functions of products are retained, reused, upgraded or adapted through de-manufacturing and re-manufacturing; and

4.Skills, standards and safety measures relevant to remanufacturing are developed.

Scope: Proposals should focus on developing de-manufacturing and re-manufacturing technologies at the factory level, addressing at least three of the following:

1.Technologies to efficiently analyse part condition and support predictive maintenance, including for re-manufactured parts or components of lower value, e.g. by combining multimodal sensor data, AI and human inputs;

2.AI and robotic-assisted technologies, e.g. innovative end-effectors, to de-manufacture products and components, including handling, sorting and extended logistics;

3.Model-based systems, to allow de-manufacturing and re-manufacturing operators to use CAD data and digital twins related to the original parts (and contribute to the development of a digital ecosystem);

4.Solutions allowing local (on-site) repair or re-manufacturing of high-added value components (applied to e.g. wind turbines, aircraft and vessels); and

5.Solutions to plan the sequence of operations based on the characteristics of the incoming products to be re-manufactured.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination. Depending on the approaches to be pursued, these should consider the best solutions to enhance adoption, for example coupling manufacturing with de-/re- manufacturing plants, product and component value, risk mitigation for variable de-/re-manufacturing flows.

This topic implements the co-programmed European Partnership Made in Europe.

HORIZON-CL4-2026-01-MAT-PROD-04: Optimise the usage of resources in a circular economy (RIA) (Processes4Planet and Clean Steel partnerships)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 8.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 64.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Technology Readiness Level

Activities are expected to start at TRL 4-5 and achieve TRL 6 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering also support for the steel sector, grants will be awarded to applications not only in order of ranking but at least also to two proposals that are the highest ranked that focus on the recovery of iron-containing residuals / waste / by-products using low-CO2 processes; provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 39 .

Expected Outcome: Projects are expected to contribute to one or more of the following outcomes:

1.Material recycling and upcycling are significantly enhanced compared to the state of the art through technology development along the value chain and integrated value chain optimisation, leading to reduced GHG and air pollutant emissions;

2.Through the recycling of (iron-containing or other) production waste / residuals / by-products or optimisation of the recovery of critical / strategic raw materials or ferroalloys, the EU’s dependencies on imports from single or very limited numbers of country suppliers are reduced, and the yields of recycling of production-waste / by-products are increased;

3.The usage of raw materials, fresh water and energy is minimised, and ecosystem and habitat degradation avoided;

4.The impact of impurities in materials produced for special applications of strategic importance for European environmental, social and governance (ESG) 40 sustainability is reduced by either minimising their amount or by modification of impurity-material-structure, morphology, and properties;

5.Cost efficient use of resources is reached with minimal energy usage and optimized use of labour.

Scope: The topic aims to optimise the efficiency of materials, water and energy use by recycling and upcycling of side streams from production and end-of-use waste, to become more competitive, safe and sustainable. Material production becomes less dependent on imports and / or use of non-renewable materials by improving recovery along the value chain, developing and upscaling low-CO2 processes to recover materials, including to replace current efficient but CO2-intensive recycling.

The continuity and high resource demand for materials and energy of industrial processes need dependable availability of resources. The attainment of this target requires moving away from primary, often expensive, and rare resources, by the re-integration and valorisation of secondary resources (end-of-use waste) and industrial side-streams into the process industries as feedstock. Priority should be given to streams that contain critical and insufficiently available raw materials, and to streams with a large carbon footprint or a large required energy input for their production.

The development of technologies should encompass the entire value chain from the collection, dismantling, sorting and separation of waste to the processing of the streams and the production of new high-quality materials. The demonstration of the innovative, efficient, and economically viable technologies is required, considering a scale and conditions that can give reliable indications on the real-world economic potential. Minimizing the intake of energy and water should be considered.

Proposals under this topic are expected to address at least 3 of the following points:

1.Increase the share of sustainable feed streams of the process industries from end-of-use waste and/or foster circular material flows in house and/or across sites of iron-containing and other residuals / waste / by-products, avoiding incineration or disposal, including the development / upscaling of low CO2 processes with reduced negative impact on air quality;

2.Improve product designs including by-products for easier re-cycling and upcycling;

3.Enhance existing technologies for a more efficient residual / waste / by-products collection, sorting, classification, characterisation, treatment, processing and re-use. This can include development / improvement of end-of-life recycling processes targeting waste, scrap, dust and sludges for possible use for high-performance high-reliability products;

4.Recover relevant secondary raw materials, including critical ones, and target maximum process efficiency;

5.Reduce the usage of scarce and critical raw materials in the production processes, while at the same time preserving ecosystem and reducing pressures on biodiversity that would be caused by extraction;

6.Reduce the number of manufacturing stages by shortening of production processes, leading to a reduction in the energy consumption; and/or consider approaches/technologies for optimising efficiency in terms of water use.

7.Understand the effect of specific contaminants on the properties of materials produced from secondary feedstock and develop technologies for their removal if needed, also in view of the need for pre-treatment and secondary manufacturing steps.

8.Where relevant, include analytical techniques for micro- and/or nano-characterisation of materials to gain the necessary knowledge to influence processes and allow dedicated modelling.

Showcase improved performance, scalability and cost efficiency of the proposed solution through at least one case at laboratory level pilot scale. Digitalisation should be included when effective, but it must not be targeted independently from the development and validation of the necessary process technologies.

The re-integration of side streams in the production cycle can take place within one sector or across sectors (industrial symbiosis). Impacts of regulations must be considered and proposals for their modification and/or enhancement should be suggested where required.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

This topic implements the co-programmed European Partnerships Processes4Planet and Clean Steel.

HORIZON-CL4-2026-01-MAT-PROD-05: Circular innovative advanced materials: facilitating the transition from design to markets (RIA) (Innovative Advanced Materials for the EU and Made in Europe partnerships)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 6.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 37.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Technology Readiness Level

Activities are expected to start at TRL 4-5 and achieve TRL 6 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering strategic value chains, grants will be awarded to applications not only in order of ranking but at least also to one proposal that is the highest ranked from each of the following areas: (i) mobility and (ii) medical devices; provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 41 .

Expected Outcome:

1.Innovative advanced materials designed for circularity are adopted in products faster, through accelerated production and technology uptake;

2.Business models become available to enhance the use of circular innovative advanced materials in strategic value chains; and

3.Resource efficiency (materials and energy) is increased significantly through a focus on circular advanced materials.

4.Quality standards, harmonisation and regulatory requirements are addressed facilitating simplified market transition.

Scope: The focus of this topic is on enabling circularity and resilient supply networks through R&I in advanced materials, in particular recyclable polymers and composites, magnets and metal (alloys) for additive manufacturing, and on accelerating their pathway to market. Proposals should develop new innovative advanced materials (IAMs) with superior or novel functionalities designed for circularity. The scope includes necessary developments of related processes and technologies to ensure integration in industrial manufacturing facilitating uptake of the developed solutions. Proposals should also develop circular business models considering the cost of changes needed along the life cycle of these new materials to facilitate their uptake.

The scope covers the full innovation cycle from the design for circularity and functional integration (new materials designs), development and scaleup (including scalable recovery, recycling and valorisation at end of life), to demonstration of industrial uptake and integration into products. The transformative potential of the developed solutions is to be showcased by demonstrators and industrial use cases. Projects should also explore possibilities to transfer developed solutions to other applications or sectors.

The SSbD framework 42 should guide the innovation process towards safer and more sustainable chemicals and advanced materials. Where relevant data generated within the proposal may be shared with the Common Data Platform for Chemicals. The new alternatives to be developed should meet the technical functions required in the specific applications while aligning their innovation process decision making with such framework.

Best use of digital tools and FAIR data, including AI and data-driven approaches throughout the innovation process should support the circular transition for industry and circular product design. This includes sharing FAIR and interoperable data and tools across supply networks and value chains, to foster circularity, including data needed for materials and component development, production and circular product design. Proposals should adhere to the FAIR data principles and adopt wherever relevant, data standards and data sharing/access good practices.

The approach should foster collaboration among stakeholders along the innovation chain and industrial value networks to accelerate the development and adoption of new circular solutions.

Projects should build on, or seek collaboration with, existing projects in EU Member States and Associated Countries and develop synergies with other relevant European, national or regional initiatives, funding programmes and platforms, in particular with the Materials Commons for Europe.

Proposals should support strategic value chains in the fields of mobility and medical devices. The portfolio approach will be used to fund at least one proposal from each of these two areas. Proposers should declare in their proposal the main application area of their proposal (i.e. mobility or medical devices).

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

This topic implements the co-programmed European Partnerships Innovative Advanced Materials for the EU (IAM4EU) and Made in Europe (MiE).

HORIZON-CL4-2027-01-MAT-PROD-06: Circular innovative advanced materials: facilitating the transition from design to markets (RIA) (Innovative Advanced Materials for the EU and Made in Europe partnerships)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 6.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 36.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Technology Readiness Level

Activities are expected to start at TRL 4-5 and achieve TRL 6 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering strategic value chains, grants will be awarded to applications not only in order of ranking but at least also to one proposal that is the highest ranked from each of the following areas: (i) energy and (ii) construction; provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 43 .

Expected Outcome:

1.Innovative advanced materials designed for circularity are adopted in products faster, through accelerated production and technology uptake;

2.Business models become available to enhance the use of circular advanced materials in strategic value chains; and

3.Resource efficiency (materials and energy) is increased significantly through a focus on circular advanced materials.

4.Quality standards, harmonisation and regulatory requirements are addressed facilitating simplified market transition.

Scope: The focus of this topic is on enabling circularity and resilient supply networks through R&I in advanced materials, in particular recyclable polymers and composites, magnets and metal (alloys) for additive manufacturing, and on accelerating their pathway to market. Proposals should develop new innovative advanced materials (IAMs) with superior or novel functionalities designed for circularity. The scope includes necessary developments of related processes and technologies to ensure integration in industrial manufacturing facilitating uptake of the developed solutions. Proposals should also develop circular business models considering the cost of changes needed along the life cycle of these new materials to facilitate their uptake.

The scope covers the full innovation cycle from the design for circularity and functional integration (new materials designs), development and scaleup (including scalable recovery, recycling and valorisation at end of life), to demonstration of industrial uptake and integration into products. The transformative potential of the developed solutions is to be showcased by demonstrators and industrial use cases. Projects should also explore possibilities to transfer developed solutions to other applications or sectors.

The SSbD framework 44 should guide the innovation process towards safer and more sustainable chemicals and advanced materials. Where relevant data generated within the proposal may be shared with the Common Data Platform for Chemicals. The new alternatives to be developed should meet the technical functions required in the specific applications while aligning their innovation process decision making with such framework.

Best use of digital tools and FAIR data, including AI and data-driven approaches throughout the innovation process should support the circular transition for industry and circular product design. This includes sharing FAIR and interoperable data and tools across supply networks and value chains, to foster circularity, including data needed for materials and component development, production and circular product design.

The approach should foster collaboration among stakeholders along the innovation chain and industrial value networks to accelerate the development and adoption of new circular solutions.

Projects should build on, or seek collaboration with, existing projects in EU Member States and Associated Countries and develop synergies with other relevant European, national or regional initiatives, funding programmes and platforms, in particular with the Materials Commons for Europe.

Proposals should support strategic value chains in the fields of energy and construction. The portfolio approach will be used to fund at least one proposal from each of these two. Proposers should declare in their proposal the main application area of their proposal (i.e., energy or construction).

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

This topic implements the co-programmed European Partnerships Innovative Advanced Materials for the EU (IAM4EU) and Made in Europe (MiE).

HORIZON-CL4-2027-01-MAT-PROD-08: Textile circularity through advanced processing and manufacturing technologies and system approaches (IA) (Textiles for the Future partnership)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.00 and 6.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 16.00 million.

Type of Action

Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 6-7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Beneficiaries may provide financial support to third parties. The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 150 000. This derogation is justified by the fact that the actions to be carried out by third parties (SMEs) towards the expected outcome of the uptake of business models and system approaches, will be incorporating cost-intensive technologies to process textile-to-textile recycled materials.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 45 .

Expected Outcome:

1.Increased economically viable and functionally equivalent renewable material and sustainable chemical solutions used in large scale textile applications, including apparel, home and technical textiles;

2.A realistic pathway for an absolute reduction of the use of virgin fossil-based materials and chemicals used to produce textile products for the EU market by 2035, contributing to enhance the preservation of human health, biodiversity and ecosystems, whether aquatic or terrestrial ecosystem preservation and emission reduction;

3.Uptake of business models and system approaches that allow for the scale up of sustainable textile material and chemical alternatives as competitive alternatives to conventional approaches.

Scope: Innovative renewable textile fibres and sustainable chemical solutions today face almost insurmountable cost disadvantages compared to extremely cost-competitive and industrially entrenched fibres and chemicals based on virgin fossil resources. To allow for the scale up of the use of innovative renewable materials and sustainable chemicals by the textile industry, improved processability of materials, suitable processing technology, deeper technical knowledge and smart phase-in approaches such as material blending or drop-in solutions are required. Specific emphasis must be placed on resulting final product quality, their durability and functionality to avoid negative user/consumer perception of products made with renewable materials and sustainable chemicals. As not all cost and quality challenges may be immediately overcome by technological innovation, accompanying business models and systems approaches are needed to enable equitable cost and risk sharing among all involved stakeholders in the textile value chain.

Attributes such as recyclability, recycled material content, and resource efficiency as well as reduced carbon and environmental footprint are expected to be part of the textile-specific requirements under the Ecodesign for Sustainable Products Regulation.

Proposals should specifically address:

1.Innovative processing technologies to facilitate the efficient use of recycled, regenerated and bio-based fibres as well as sustainable processing and functionalising chemicals across all major stages of the textile manufacturing value chain, such as spinning, weaving, knitting, dyeing or finishing;

2.Quantification of biodiversity outcomes associated to new processes by using existing Monitoring, Reporting and Validation (MRV) methodologies, adapting and testing them if needed;

3.Characterisation, quality assurance and mitigation strategies for the most common processing and functionality challenges and limitations of the sustainable materials and chemicals targeted;

4.Development of best practices and training materials targeted at designers, manufacturers, brands, end of life managers and end users, working with the targeted materials and chemicals;

5.Strategies and tools to practically implement collective risk sharing and smart scaling approaches.

Proposals should actively involve suppliers of renewable materials and sustainable chemicals, brands, commercial end users and developers/manufacturers of relevant processing technology and industrial partners with the capacity to commercially scale up production with the targeted materials and chemicals. The involvement of partners beyond the manufacturing supply chain, such as product designers, brands, commercial end users and end of life managers including collectors, sorters, recyclers and remanufacturers is particularly encouraged. Proposals should carry out research and innovation to develop missing elements and achieve the necessary integration, including economic viability. Hence, synergies with, or using results from, other projects may be appropriate. The mere integration of existing technologies or processes is outside the scope of this topic.

Proposals should provide between 10% and 25% of the EU contribution through financial support to third parties (FSTP), in order to maximise the number of SMEs involved in small-scale innovation projects. FSTP funding can be provided only to SME participants, while the active participation of larger companies in such innovation projects in encouraged. The involvement of start-ups is also specifically encouraged.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

This topic implements the co-programmed European Partnership Textiles for the Future.

Disruptive technologies for carbon capture and clean energy use

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-01-MAT-PROD-31: Efficient capture / purification / utilisation of CO2 for the production of competitive products (RIA) (Processes4Planet partnership)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 7.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 43.80 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Technology Readiness Level

Activities are expected to start at TRL 4-5 and achieve TRL 6 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 46 .

Expected Outcome: Projects are expected to contribute to the following outcomes:

1.Achieve a significant reduction in the production costs of CO2-based products, making them competitive with conventionally produced alternatives. This involves optimising the integration of CO2 capture, purification, and conversion processes.

2.Demonstrate processes that minimize energy consumption during the entire conversion process, leveraging advances in process integration that can shift equilibria and the use of renewable electricity and available heat sources.

3.Contribute to the reduction of carbon emissions by enabling the sustainable use of CO2, supporting circular economy principles through the valorisation of CO2, possibly aligned with CCS.

Scope: There are only a few products that can be competitively produced from CO2. Increased opportunities for CCU from process industry emissions require the development of a larger portfolio of potential CO2-derived products. The higher cost of CO2-based products compared to conventional production routes is mostly driven by the high energy demand arising from the thermodynamic constraints of CO2. The smart integration of CO2 capture, purification and conversion can enable process optimisation with reduced energy consumption as well as reduced capital expenditure. Additionally, innovative processes can overcome the inherent equilibrium limitations of CCU production. The development of new integrated processes can be an opportunity to optimise the use of electricity, make use of available heat sources and relevant infrastructures and thus accelerate the development of CO2 valorisation.

Proposals under this topic are expected to address several of the following points:

1.Develop new methodologies, processes and technologies for the smart integration of CO2 capture, purification, and conversion, focusing on reducing energy demand, capital expenditure and possible integration with CCS infrastructure requirements.

2.Incorporate renewable energy sources (including the fluctuation of energy availability) and innovative energy management strategies to enhance the sustainability and cost-effectiveness of the CO2 valorisation processes.

3.Identify and integrate available heat sources and existing infrastructures to enhance process efficiency and reduce operational costs.

4.Address the constraints related to CO2 conversion processes, employing innovative approaches to maximize yield and process efficiency, for example by overcoming low equilibrium yields.

5.Conduct comprehensive lifecycle and economic assessments to ensure that the proposed solutions are viable, sustainable, and economically attractive.

Conversion of CO2 to methanol and fuels is considered outside the scope of this topic.

Showcase improved performance, scalability and cost efficiency of the proposed solution through at least one case at laboratory level pilot scale.

The inclusion of a GHG avoidance methodology 47 is recommended and should provide detailed descriptions of baselines and projected emissions reduction.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination, underlining how the proposal will serve the purpose to boost industrial decarbonisation technologies supply chain in Europe. Proposals should consider representative real industrial sites demonstrating the solutions at least in open-loop computations. This should be done in parallel to the actual operation of the plants with validation of the benefits by simulations with accurate models. Experiments involving real industrial sites are encouraged. Societal- and environmental impact as well as implications for the workplace (including skills and organisational change) should be outlined.

This topic implements the co-programmed European partnership Processes4Planet.

HORIZON-CL4-2027-02-MAT-PROD-32-two-stage: Efficient energy input from renewable sources and energy management in the process industries (IA) (Processes4Planet and Innovative Advanced Materials for the EU partnerships)

Call: INDUSTRY-two-stage

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 7.00 and 9.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 52.50 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

In order to include a business case and exploitation strategy, as outlined in the introduction to Destination 'Leadership in materials and production for Europe', the page limit in part B of the General Annexes is exceptionally extended by 3 pages (for second-stage proposals).

Technology Readiness Level

Activities are expected to start at TRL 4-5 and achieve TRL 6-7 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 48 .

Expected Outcome:

1.A significant decarbonisation of processes (measured by the reduction of GHG emissions from the overall system) with broad applicability and economic viability.

2.Facilitation of the transition from fossil-based energy inputs for:

1.low/medium thermal energy demands by introducing renewable-based alternatives and heat upgrading.

2.High-temperature processes, by innovative technologies for electrified and hybrid high-temperature processes, high temperature energy storage.

3.Clean energy usage is given a boost through innovative advanced materials, system concepts and technologies for energy integration and energy storage, supporting resilience against energy supply variations

4.Combination of significant energy savings and integrated management of energy systems and production processes

Scope: Most processes in the process industries require significant energy inputs which currently lead to substantial CO2 emissions by the process industries. The reduction of the CO2 footprint can be achieved by several measures, e.g. electrification or use of other renewable sources of energy, lowering of the energy demand, increasing energy efficiency, and energy integration. This topic aims to lead to significant steps in reducing the CO2 footprint by technological innovations, at least by 20%.

A key problem in the use of renewable energy sources is their fluctuation over time. Projects should take this into account and develop solutions that aim for energy efficiency and include novel storage technologies of relevance to the process industries. Pure demand-side management by production schedules adapted to the supply of electricity from renewable sources is not within the scope of the call.

In situations where full electrification is not feasible or competitive in the foreseeable future, sustainable hybrid solutions play a crucial role. These solutions enhance flexibility, allowing industries to manage the variability in the availability of affordable renewable electricity, which is expected to fluctuate significantly in the medium term. E.g., preheating processes can utilize fossil-free energy sources such as solar heat, geothermal heat, heat pumps, resistive or induction heating, and electric boilers. This initial stage can be followed by further heating using fossil-based methods initially, and later transitioning to renewable-based combustion processes to achieve the required process temperatures.

To enhance resilience, the capture, storage, and management of energy flows should be tailored to the needs of the process industry. This may include research and innovation in safe and sustainable innovative advanced materials for (latent or sensible) energy storage, e.g. phase change materials and heat storage via chemical energy carriers beyond E-fuels.

Proposals under this topic should address several of the following:

1.Advancements in the use of energy from renewable sources in production processes with improved energy efficiency.

2.Integrated energy systems with novel storage elements to enable a smooth operation of the plants despite variations in the availability of energy from renewable sources.

3.Solutions for low/medium temperature (100 - 500 °C) energy inputs in energy intensive industries including hybrid solutions and a progressive reduction of the use of fossil carriers of energy.

4.Solutions for high temperature (> 500 °C) energy inputs in energy intensive industries, including high temperature electricity driven processes, and high temperature energy storage.

5.Application of high-performance insulation materials and new innovative advanced materials that can improve heat capture, storage, and retrieval, particularly for scalable high-temperature applications. Such materials should minimize the use of critical raw material, enabling effective recycling.

Projects should include demonstrations at pilot scale, preferably in real industrial environments, to validate the proposed technologies and processes under real-world industrial conditions

Proposals related to innovative advanced materials development should address the most relevant gaps to focus on in the frame from materials design to technology deployment and ensure adequate feedback loops between different steps to drive forward innovative solutions which can be easily deployed. Scalability and requirements from application/industry need to be considered early on in the innovation process.

The inclusion of a GHG avoidance methodology 49 is recommended and should provide detailed descriptions of baselines and projected emissions reduction.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination, underlining how the proposal will serve the purpose to boost industrial decarbonisation technologies supply chain in Europe. As project output an elaborated exploitation plan should be developed, including preliminary plans for scalability, commercialisation and deployment (feasibility study, business plan and financial model) indicating possible private and public funding sources (e.g. Innovation Fund, InvestEU and cohesion policy funds). Societal- and environmental impact as well as implications for the workplace (including skills and organisational change) should be outlined.

This topic implements the co-programmed European partnerships Processes4Planet and Innovative Advanced Materials for the EU.

Technology infrastructure, knowledge valorisation and support for scaleups and startups

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-01-MAT-PROD-41: Enhancing industry-academia knowledge exchange in Social Sciences and Humanities (SSH) (CSA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.00 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 50 .

Expected Outcome:

1.Increased innovation capabilities for industry by harnessing the potential of Social Sciences and Humanities, including the Arts, to provide effective solutions to companies' research and innovation challenges and organisational development.

2.Improved strategies to bring new products and technologies to the industry environment and ultimately to the market.

3.By facilitating industry exposure, SSH researchers’ better understanding of industry needs and opportunities for collaboration.

Scope: This action aims to leverage the strengths of social sciences, humanities and arts (SSH) to address companies' specific needs, fostering a dynamic and productive industry-academia co-creation for knowledge valorisation. This action will implement SSH–industry co-creation (for example hackathons, team-based approaches, targeted mentorship and exchange programmes etc) focussing on specific challenges from industry and SMEs including, but not limited to understanding the socio-technical implications of new technologies and innovations, broadening the perspectives of companies’ strategic actions, creating a deeper understanding of customer needs, legal requirements and pathways to the market, strengthening the integration of social, economic and cultural inequality considerations into industry practices and innovation processes, developing new ideas and innovations and contributing to organisational development, sustainability and long-term profitability.

The action will cover the following activities:

1.Developing a methodology for understanding how various needs from industry, SMEs and customers can be addressed by knowledge exchanges with SSH researchers and students.

2.Service to industry and SMEs including spinoffs and startups to support solving company challenges with international teams of SSH researchers and students.

3.A study to tackle the key questions concerning the technical and conceptual feasibility of Industry-Academia knowledge exchange with SSH to improve innovation management and organisational development.

HORIZON-CL4-2027-01-MAT-PROD-42: Unlocking the potential of academic intellectual assets for industry, SMEs and startups (CSA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.00 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 51 .

Expected Outcome:

1.Enhanced valorisation of intellectual assets, including dormant patents, from universities and public research organisations to support the adoption of green and digital technologies by industry, SMEs and start-ups/spinoffs.

2.Development of entrepreneurial skills and increased involvement of students, researchers, and innovators in the valorisation of research results.

3.Uptake of effective models and tools to facilitate valorisation of unused IP and intellectual assets and access by startups, SMEs, and innovative companies to this untapped knowledge in public research organisations.

Scope: Aligned with the European Union's policy priorities, this action will contribute to overcoming the innovation paradox by maximising the impact of public spending in R&I through improved knowledge valorisation practices, and facilitating the uptake of green and digital technologies by start-ups, spinoffs, and innovative SMEs. By unlocking the untapped potential of intellectual assets within universities and public research organisations, and leveraging the creativity of students, researchers, and innovators, the action seeks to improve value creation opportunities deriving from these assets and bolster the competitiveness of European industry.

The action should explore strategies and implement pilots for actively involving students and researchers (including those in social sciences and humanities) in valorising academic IP and intellectual assets. These should include hackathons, workshops and larger-scale “summer camp” programmes, and foresee the involvement of interested industry partners than can be potential adopters.

The action should also identify and test models and tools for easier IP access and utilisation by startups and SMEs. These should cover innovative licensing and other valorisation approaches, especially tackling the issue of unused academic patents, as well as the use of AI to manage and valorise research results and IP.

Proposals submitted under this topic should consider how to exploit synergies with other EU-funded projects covering intellectual assets management, entrepreneurship, and AI for knowledge valorisation. They should also pay particular attention to reducing the gender gap and promoting diversity in knowledge valorisation, and include dedicated measures to foster gender balance and inclusiveness in this field.

HORIZON-CL4-2027-01-MAT-PROD-61: Fast Track to Research and Innovation for breakthroughs in industrial technologies (Research and Innovation Action)

Call: INDUSTRY-FTRI

Specific conditions

Expected EU contribution per project

Up to EUR 2.50 million.

Indicative budget

The total indicative budget for the topic is EUR 20.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply: consortia may include a maximum of 6 independent eligible entities as participants.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

Indicative timetable for evaluation and grant agreement signature will be:

1.Information on the outcome of the evaluation: Maximum 4 months from the final date for submission; and

2.Indicative date for the signing of grant agreements: Maximum 6 months from the final date for submission.

To allow a faster access to funds for small collaborative consortia, grants under this topic will be funded under a Fast Track to Research and Innovation Procedure (FTRI).

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.Proposals should describe a credible pathway from their project results and outcomes towards the expected impact of this Destination;

2.Proposals should enable open-ended breakthrough innovations in industrial technologies, feeding the pipeline of knowledge.

Scope: This is an open topic, intended to cover breakthrough innovations, up to TRL 4, within the scope of the Strategic Research and Innovation Agendas (SRIAs) of the partnerships Made in Europe, Process4Planet, Clean Steel, Innovative Advanced Materials for the EU (IAM4EU) and Textiles for the Future. 52 Proposals should carefully describe their expected contribution to one or more of the R&I objectives of the respective SRIA.

HORIZON-CL4-2027-01-MAT-PROD-62: Fast Track to Innovation for breakthroughs in the Chemical Industry Action Plan (Research and Innovation Action)

Call: INDUSTRY-FTRI

Specific conditions

Expected EU contribution per project

Up to EUR 2.50 million.

Indicative budget

The total indicative budget for the topic is EUR 15.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The following additional eligibility criteria apply: consortia may include a maximum of 6 independent eligible entities as participants.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

Indicative timetable for evaluation and grant agreement signature will be:

1.Information on the outcome of the evaluation: Maximum 4 months from the final date for submission; and

2.Indicative date for the signing of grant agreements: Maximum 6 months from the final date for submission.

To allow a faster access to funds for small collaborative consortia, grants under this topic will be funded under a Fast Track to Research and Innovation Procedure (FTRI).

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.Proposals should describe a credible pathway from their project results and outcomes towards the expected impact of this Destination;

2.Enable the acceleration of the market uptake of groundbreaking innovations in the decarbonisation of the chemical industries as well as alternatives to substances of concern.

Scope: This open topic aims to speed up the adoption of new, groundbreaking innovations (starting TRL 4 ) as part of the Chemical Industry Action Plan, in the areas of decarbonisation of energy intensive industries, circular economy or breakthrough production technologies; as well as development of alternatives (new chemical substances, advanced materials or technologies) to substances of concern. Application of the SSbD Framework should be considered as appropriate.

HORIZON-CL4-2026-01-MAT-PROD-44: Attracting management talent for capacity building for Technology Infrastructures staff members (CSA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.50 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 53 .

Expected Outcome: Proposals should demonstrate the following expected outcomes:

1.Sound understanding of the competences and skills needs of Technology Infrastructures related to effective management and providing services to industry in all member states;

2.Improved and structure the training of Technology Infrastructures staff members with improved sector-agnostic competencies;

3.Increased and improved collaboration between Research and Technology Infrastructures, leading to exchange of best practices in management and capacity building in Technology Infrastructures, and peer learning;

4.Better uptake of technology infrastructure services by industry, including startups and scaleups, innovators and researchers;

5.Improved coherence, visibility and accessibility of technology infrastructures facilities and services;

6.Improved business and governance models of Technology Infrastructures.

Scope: A combination of factors including rapid technological advancements, inefficient strategic planning, skills gaps, and budget limitations can create sub-optimal technology infrastructure management. Proposals are expected to develop and provide schemes to attract management talent (including but not limited to organisational sciences) to technology infrastructures in EU member states. These management talent schemes should be aimed at attracting talents that will study the technology infrastructures needs, in terms of competencies, skills, organizations, and business models, to deliver more efficiently their services to industry, especially to SMEs, startups and scaleups. Based on this sound understanding of Technology Infrastructures needs, the attracted management talents are expected to both develop and provide advice to Technology Infrastructures senior management and trainings to their staff members aimed at increasing their capacity to develop and provide services to industry. The developed trainings should be sector-agnostic, open-source, accessible remotely, easy to update, and take stock of other existing similar initiatives and experiences in Research and Technology Infrastructures.

Proposals should propose ways to enhance skills and career profiles of technical staff working in technology infrastructures to address evolving needs such as research security, data management, quality assurance, etc., as well as further professionalising the training of managerial and leadership staff in technology infrastructures. They should help also to promote entrepreneurial skills for technology infrastructures staff in training curricula to fully capture the potential of technology infrastructures as centres of deep-tech innovation ecosystem.

Furthermore, proposals should aim to enhance transnational and multisite collaboration among Technology Infrastructures fostering the building of technology infrastructures ecosystems, the sharing of experience, resources, and best practices in management and capacity building, staff exchange and networking. These collaborations could lay the foundations of a future framework to facilitate coordination of technology infrastructures policy and priority setting at EU level as well as exchange of experience and good practices. Proposals may also benefit, especially for communication and dissemination activities, from sharing best practices and taking stock of what other relevant projects are developing in the field of Technology Infrastructures. Existing specific best management practices and European frameworks in the technology fields considered by the proposals have to be taken into account.

HORIZON-CL4-2026-01-MAT-PROD-45: Pilot access schemes to Technology Infrastructures for European startups, scaleups and innovative SMEs (CSA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 1.50 and 2.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.00 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 54 .

Expected Outcome: Proposals should demonstrate the following expected outcomes:

1.A sound understanding of the specific needs of industrial users (including but not limited to innovative SMEs, startups and scaleups) for Technology infrastructure services in specific priority areas including but not limited to advanced materials, clean energy, or health and biotechnology;

2.Increased opportunities for industrial users for development, testing, up-scaling and deployment of new technologies via the use of services offered by Technology Infrastructures;

3.Strengthened innovation and technology development capacity of European SMEs, startups and scaleups via improved access to Technology Infrastructures;

4.Attractiveness and effectiveness of the developed access schemes for broadening the range of Technology Infrastructures users, especially for startups and scaleups, including with transnational access.

Scope: Startups, scaleups and other innovative SMEs require access to state-of-the-art research and technology facilities, equipment and expertise to test, upscale, validate new products and technologies, shortening the time-to-market and increasing the chances for a successful commercialisation. Access mechanisms to Technology Infrastructures as well as access contracts and collaboration or service provision agreements are often complex, while the costs of using such infrastructures can significantly surpass the financial capacities of growing innovative companies.

The action will develop and test pilot multi-site access schemes for startups, scaleups and other innovative SMEs, involving a critical mass of Technology Infrastructures operators and users in priority areas (including but not limited to advanced materials, clean energy, or health and biotechnology). It should build on existing initiatives with already developed single access points to a comprehensive set of facilities and services in a selected technology area, like for example Open Innovation Test Beds or other integrated networks, that allow for a quick deployment of a common access scheme.

The action should include setting-up a pilot centrally managed and funded access programme, allowing companies quick access to the needed services, with simplified and standardised access conditions applicable across the EU, to be coordinated and in line with the work on the envisaged European Charter of access for industrial users to research and technology infrastructures. While the focus shall be the provision of access and support services to companies, the action can also include enhancing the accessibility and usability of technology infrastructure services to ensure that they meet the evolving needs of users.

The action should aim at significant broadening of the user base of the technology infrastructures to address the needs of startups and scaleups that do not have access to such facilities in their local ecosystems. To this end, proposals should include the development and implementation of activities to increase the visibility and promote and demonstrate the uptake of technology infrastructures services provided to users across the EU.

Furthermore, proposals should aim to enhance transnational and multisite collaboration among Technology Infrastructures fostering the building of technology infrastructures ecosystems, the sharing of experience, resources, and best practices in management, service offer, staff exchange and networking. Proposals may also benefit, especially for communication and dissemination activities, from sharing best practices and taking stock of what other relevant projects are developing in the field of Technology Infrastructures.

HORIZON-CL4-2026-01-MAT-PROD-46: Mapping and service finder for Technology Infrastructures (CSA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 2.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.00 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 55 .

Expected Outcome:

1.Improved visibility and access to technology infrastructures via an interactive portal (open source, free to access, easy to update) of technology infrastructures across Europe;

2.Improved understanding of the European landscape of technology infrastructures, including existing facilities and their services supporting the development of strategic technologies by industrial users;

3.Boosted innovation and market potential by providing an interactive portal where industrial users, especially SMEs, startups and scaleups, can search and find services relevant for their innovation and product development.

Scope: For many innovative startups, finding and accessing highly specific research and technology infrastructures services is a major hurdle. Information about the available services is limited, especially on infrastructures located beyond their local ecosystems.

Proposals are expected to create an inventory of existing and ongoing mapping of technology infrastructure and technology infrastructure services in Europe and to consolidate the knowledge into an interactive portal that will serve as technology infrastructure service finder.

Furthermore, based on this inventory and other existing evidence-gathering and policy analysis, the proposals should use a comprehensive taxonomy of the technology infrastructures landscape. The portal, in line with regional smart specializations and existing ecosystems, should help assess which new technology infrastructure needs to be built to ensure long-term Europe’s competitiveness and sovereignty.

Proposals should set out to establish an interactive portal including an interactive finder for technology infrastructure services in the EU. The finder should be aligned with other ongoing activities such as EIB TechEU, EIB Advisory services and other relevant tools identified during the inventory stage. The interactive finder should facilitate the cooperation between technology infrastructure operators with industry (including SMEs, startups and scaleups) and other relevant stakeholders and propose services from a demand driven perspective. It should lead to increased opportunities for startups and scaleups for development, testing, up-scaling and deployment of new technologies.

The developed platform should be based on open-sources technologies, allowing interoperability with parallel initiatives and self-sustainability on long-term, and propose a suitable opensource application interface (API) or develop an open-source API that will allow flow of information between technology infrastructure service providers. The CSA could support the maintenance of the platform for at least 5 years.

Proposals should include also communication actions aimed at increasing the visibility and uptake of the finder and of technology infrastructures across the EU as well as activities to facilitate dialogue and networking among stakeholders. This should include promoting the uptake of the platform.

Furthermore, the proposal should develop a model to make the platform self-sustainable on the long-term, through, but not only limited to, proper governance, financing and other relevant aspects.

Proposals should also aim at enhancing transnational and multisite collaboration among Technology Infrastructures and their users, fostering the building of technology infrastructures ecosystems, the sharing of experience, resources, best practices service development and service offer, feedback from users, staff exchange and networking. Proposals may also benefit, especially for communication and dissemination activities, from sharing best practices and taking stock of what other relevant projects are developing in the field of Technology Infrastructures.

HORIZON-CL4-2027-01-MAT-PROD-47: Pilot access schemes to Technology Infrastructures for European startups, scaleups and innovative SMEs (CSA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 1.50 and 2.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.00 million.

Type of Action

Coordination and Support Actions

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 56 .

Expected Outcome: Proposals should demonstrate the following expected outcomes:

1.A sound understanding of the specific needs of industrial users (including but not limited to innovative SMEs, startups and scaleups) for Technology infrastructure services in specific priority areas including but not limited to advanced materials, clean energy, or health and biotechnology;

2.Increased opportunities for industrial users for development, testing, up-scaling and deployment of new technologies via the use of services offered by Technology Infrastructures;

3.Strengthened innovation and technology development capacity of European SMEs, startups and scaleups via improved access to Technology Infrastructures;

4.Attractiveness and effectiveness of the developed access schemes for broadening the range of Technology Infrastructures users, especially for startups and scaleups, including with transnational access.

Scope: Startups, scaleups and other innovative SMEs require access to state-of-the-art research and technology facilities, equipment and expertise to test, upscale, validate new products and technologies, shortening the time-to-market and increasing the chances for a successful commercialisation. Access mechanisms to Technology Infrastructures as well as access contracts and collaboration or service provision agreements are often complex, while the costs of using such infrastructures can significantly surpass the financial capacities of growing innovative companies.

The action will develop and test pilot multi-site access schemes for startups, scaleups and other innovative SMEs, involving a critical mass of Technology Infrastructures operators and users in priority areas (including but not limited to advanced materials, clean energy, or health and biotechnology). It should build on existing initiatives with already developed single access points to a comprehensive set of facilities and services in a selected technology area, like for example Open Innovation Test Beds or other integrated networks, that allow for a quick deployment of a common access scheme.

The action should include setting-up a pilot centrally managed and funded access programme, allowing companies quick access to the needed services, with simplified and standardised access conditions applicable across the EU, to be coordinated and in line with the work on the envisaged European Charter of access for industrial users to research and technology infrastructures. While the focus shall be the provision of access and support services to companies, the action can also include enhancing the accessibility and usability of technology infrastructure services to ensure that they meet the evolving needs of users.

The action should aim at significant broadening of the user base of the technology infrastructures to address the needs of startups and scaleups that do not have access to such facilities in their local ecosystems. To this end, proposals should include the development and implementation of activities to increase the visibility and promote and demonstrate the uptake of technology infrastructures services provided to users across the EU.

Furthermore, proposals should aim to enhance transnational and multisite collaboration among Technology Infrastructures fostering the building of technology infrastructures ecosystems, the sharing of experience, resources, and best practices in management, service offer, staff exchange and networking. Proposals may also benefit, especially for communication and dissemination activities, from sharing best practices and taking stock of what other relevant projects are developing in the field of Technology Infrastructures.

HORIZON-CL4-2026-01-MAT-PROD-48: ‘Proof of market’ to improve valorisation and commercialisation of Horizon generated R&I results (IA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 0.20 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.The commercial potential of Horizon research results is explored;

2.Results of Horizon projects are valorised, by ensuring a pathway to commercialisation; and

3.Startups and SMEs become involved in valorisation.

Scope: The EU must do better in translating the knowledge generated by the Framework Programme into innovations with economic and societal value.

The objective of this action is to provide financial support (‘Proof of market’) to small consortia (i.e. spin-offs, startups, SMEs) to explore the exploitation potential, in the EU, of achieved results from ongoing or completed projects funded under Cluster 4 ‘Digital, Industry and Space’ or its predecessor activities under the Leadership in enabling and industrial technologies (LEIT) 57 part of Horizon 2020.

The consortia do not necessarily have to be made of former or current beneficiaries but should own or have access to the knowledge assets of projects, including intellectual property, where relevant.

Proposals should envisage valorisation activities, such as:

1.demonstrating a technology (e.g. testing);

2.defining a commercialisation process;

3.undertaking:

1.a market and competitiveness analysis;

2.a technology assessment and/or certification;

3.a verification of innovation potential;

4.assessing potential “end users” of the expected innovation;

5.testing, piloting with users or potential customers;

6.complying with regulatory compliance and standards;

7.consolidating IP rights.

Proposals should address achieved results from ongoing or completed Research and Innovation Actions and Innovation Actions (RIA/IA) funded directly under the work programmes of Horizon Europe Cluster 4 ‘Digital, Industry and Space’ or its predecessor activities under the Leadership in enabling and industrial technologies (LEIT) part of Horizon 2020.

Applicants can be owners of the achieved results from previous projects or new participants. Proposals should include at least one of the following:

1.Confirmation that at least one of the applicants of the current proposal is the owner or holder of the relevant knowledge assets including Intellectual Property Rights (IPR) and possesses the necessary rights to commercialise the results for the entire duration of the proposed project, or

2.Commitment letter from the owner(s) of the relevant result(s) confirming the owner(s)’ willingness to negotiate fair, reasonable, and non-discriminatory access to the results, including IPR where relevant, for the purpose of future commercial exploitation.

The proposal should specify the grant number and acronym of the project(s) which generated the results.

Proposals should present a clear vision of the intended pathway to market. Hence, the participation of a business partner should be envisaged.

HORIZON-CL4-2027-01-MAT-PROD-49: ‘Proof of market’ to improve valorisation and commercialisation of Horizon generated R&I results (IA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 0.20 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 5.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.The commercial potential of Horizon research results is explored;

2.Results of Horizon projects are valorised, by ensuring a pathway to commercialisation; and

3.Startups and SMEs become involved in valorisation.

Scope: The EU must do better in translating the knowledge generated by the Framework Programme into innovations with economic and societal value.

The objective of this action is to provide financial support (‘Proof of market’) to small consortia (i.e. spin-offs, startups, SMEs) to explore the exploitation potential, in the EU, of achieved results from ongoing or completed projects funded under Cluster 4 ‘Digital, Industry and Space’ or its predecessor activities under the Leadership in enabling and industrial technologies (LEIT) 58 part of Horizon 2020.

The consortia do not necessarily have to be made of former or current beneficiaries but should own or have access to the knowledge assets of projects, including intellectual property, where relevant.

Proposals should envisage valorisation activities, such as:

1.demonstrating a technology (e.g. testing);

2.defining a commercialisation process;

3.undertaking:

1.a market and competitiveness analysis;

2.a technology assessment and/or certification;

3.a verification of innovation potential;

4.assessing potential “end users” of the expected innovation;

5.testing, piloting with users or potential customers;

6.complying with regulatory compliance and standards;

7.consolidating IP rights.

Proposals should address achieved results from ongoing or completed Research and Innovation Actions and Innovation Actions (RIA/IA) funded directly under Cluster 4 ‘Digital, Industry and Space’ or its predecessor activities under the Leadership in enabling and industrial technologies (LEIT) part of Horizon 2020.

Applicants can be owners of the achieved results from previous projects or new participants. Proposals should include at least one of the following:

1.Confirmation that at least one of the applicants of the current proposal is the owner or holder of the relevant knowledge assets including Intellectual Property Rights (IPR) and possesses the necessary rights to commercialise the results for the entire duration of the proposed project, or

2.Commitment letter from the owner(s) of the relevant result(s) confirming the owner(s)’ willingness to negotiate fair, reasonable, and non-discriminatory access to the results, including IPR where relevant, for the purpose of future commercial exploitation.

The proposal should specify the grant number and acronym of the project(s) which generated the results.

Proposals should present a clear vision of the intended pathway to market. Hence, the participation of a business partner should be envisaged.

Raw Materials

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-01-MAT-PROD-11: Innovative technologies and tools for exploration and data modelling of raw materials (RIA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 7.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 18.50 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

To increase EU resilience in raw materials supply chains and thus reduce the serious risk to the Union's strategic assets, economic and societal interests, autonomy and security associated with the current EU reliance on a few third countries for critical raw materials, by increasing sustainable and responsible sourcing of primary and secondary raw materials necessary to enable the green and digital transition and in alignment with the objectives of the Critical Raw Materials Act 59 , participation in this topic is limited to legal entities established in Member States, associated countries, OECD countries, African Union Member States, MERCOSUR, CARIFORUM, Andean Community and countries with which the EU has concluded strategic partnerships on raw materials 60 as well as trade agreements (or association/economic partnership or equivalent agreements, including the new Clean Trade and Investment Partnerships) containing raw materials cooperation provisions (i.e. Energy and Raw materials chapters) 61 . The choice of these countries was made taking into consideration the development of strategic international partnerships on raw materials and avoidance of reinforcing existing over-dependencies, as well as the importance of involving partners committed to pursuing open trade in such materials.

Proposals including legal entities which are not established in the countries that fall under the criteria above will be ineligible.

For the duly justified and exceptional reasons listed above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or a non-eligible country entity, shall not participate in the action.

Technology Readiness Level

Activities are expected to start at TRL 3-4 and achieve TRL 5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 62 .

Expected Outcome:

1.Increase information on the European Union raw materials, particularly critical raw materials occurrences and deposits, while contributing to the implementation of the National exploration programme,(article 19 of the Critical Raw Materials Regulation(CRMA) 63 .

2.Improve knowledge base of EU raw materials to identify new areas for exploration and resource estimation;

3.Accelerate development of EU domestic raw materials exploration projects integrating innovative technologies that can form the basis for new EU SMEs;

4.Develop innovative exploration data acquisition, processing and modelling and mineral system analysis for identification of critical raw materials deposits in the EU;

5.Projects will provide technologies and data which will strengthen EU Geological Surveys capacities and skills to implement the National Exploration programmes as defined in the CRMA.

6.Accelerate development of EU domestic raw materials exploration projects by junior mining / exploration companies.

Scope: Actions should develop and validate advanced geological modelling and mineral system analysis using multi-source data (geological, geophysical, and geochemical) from ground-based and remote-sensing techniques to develop high-resolution 3D models of mineral deposits. The integration of new (AI and machine learning) and conventional methods will be necessary to predict with the greatest accuracy the location of mineral deposits of critical raw materials and their carrier minerals. Actions contributing to the National exploration programmes under the article 19 of CRMA is encouraged.

Actions should develop new knowledge and conceptual models, supported by innovative technologies to strengthen and secure the EU’s supply of primary raw materials by:

1.Generating better geological understanding (i.e. characterization, modelling, mapping) of known mineral deposits to facilitate discovery of new resources, including mineral systems carrying critical raw materials;

2.Collecting new geological, geophysical, and geochemical data and developing ore genetic models and mineral system analysis to build a broad understanding of EU’s deposit type, including critical raw materials in order to identify areas for exploration, especially in previously underexplored regions;

3.Advancing mineral prospectivity modelling processes;

4.Facilitate the integration of existing multi-datasets with newly acquired data.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination.

HORIZON-CL4-2026-01-MAT-PROD-12: Technologies for innovative extraction of critical raw materials (RIA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 5.00 and 7.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 19.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

To increase EU resilience in raw materials supply chains and thus reduce the serious risk to the Union's strategic assets, economic and societal interests, autonomy and security associated with the current EU reliance on a few third countries for critical raw materials, by increasing sustainable and responsible sourcing of primary and secondary raw materials necessary to enable the green and digital transition and in alignment with the objectives of the Critical Raw Materials Act 64 , participation in this topic is limited to legal entities established in Member States, associated countries, OECD countries, African Union Member States, MERCOSUR, CARIFORUM, Andean Community and countries with which the EU has concluded strategic partnerships on raw materials 65 as well as trade agreements (or association/economic partnership or equivalent agreements, including the new Clean Trade and Investment Partnerships) containing raw materials cooperation provisions (i.e. Energy and Raw materials chapters) 66 . The choice of these countries was made taking into consideration the development of strategic international partnerships on raw materials and avoidance of reinforcing existing over-dependencies, as well as the importance of involving partners committed to pursuing open trade in such materials.

Proposals including legal entities which are not established in the countries that fall under the criteria above will be ineligible.

For the duly justified and exceptional reasons listed above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or a non-eligible country entity, shall not participate in the action.

Technology Readiness Level

Activities are expected to start at TRL 3-4 and achieve TRL 5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 67 .

Expected Outcome:

1.Increasing availability of efficient, cost-effective and innovative raw materials extraction technologies in the medium and long term.

2.Increasing the potential for primary sourcing ofEU based of raw materials deposits;

3.Improving the responsible supply of raw materials to the EU, and contributing to the Critical Raw Materials Act (CRMA) 68 objectives (Article 1).

4.Substantially reducing greenhouse gases (GHGs) and air pollutant emissions intensity per ton of the extracted material (metal, metal content, concentrate, mineral) while improving the impacts on habitat protection, ecosystem health and biodiversity.

Scope: Actions should develop and validate new sustainable concepts and technological solutions, for mining of complex or difficult to access mineral deposits, including abandoned mining sites, particularly addressing the challenges of accessibility, efficiency, industrial viability, safety and environmental and health impacts, including but not limited to water use, water, soil and air pollution, deforestation, biodiversity, ecosystem health, erosion, desertification, and GHG intensity of extraction.

Actions should assess how their technological solutions can deliver measurable biodiversity outcomes

The mining industry and users of targeted raw materials should assume a prominent role in the proposed actions, supported by adequate allocation of resources. The actions should duly justify the relevance of all targeted minerals and metals. Priority are the EU critical raw materials. Deep sea mining is not in the scope of this topic.

Actions should envisage clustering activities with other relevant selected projects for cross-projects co-operation, consultations and joint activities on cross-cutting issues and share of results as well as participating in joint meetings and communication events. To this end proposals should foresee a dedicated work package and/or task, and earmark the appropriate resources accordingly.

Proposals submitted under this topic must include a business case and a credible exploitation strategy, covering all required elements as outlined in the introduction to this Destination.

International cooperation is encouraged with countries with which the EU has signed Strategic Partnerships on raw materials, especially with Ukraine. 69

HORIZON-CL4-2026-01-MAT-PROD-13: Monitoring of secondary raw materials (CSA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 4.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

To increase EU resilience in raw materials supply chains and thus reduce the serious risk to the Union's strategic assets, economic and societal interests, autonomy and security associated with the current EU reliance on a few third countries for critical raw materials, by increasing sustainable and responsible sourcing of primary and secondary raw materials necessary to enable the green and digital transition and in alignment with the objectives of the Critical Raw Materials Act 70 , participation in this topic is limited to legal entities established in Member States, associated countries, OECD countries, African Union Member States, MERCOSUR, CARIFORUM, Andean Community and countries with which the EU has concluded strategic partnerships on raw materials 71 as well as trade agreements (or association/economic partnership or equivalent agreements, including the new Clean Trade and Investment Partnerships) containing raw materials cooperation provisions (i.e. Energy and Raw materials chapters) 72 . The choice of these countries was made taking into consideration the development of strategic international partnerships on raw materials and avoidance of reinforcing existing over-dependencies, as well as the importance of involving partners committed to pursuing open trade in such materials.

Proposals including legal entities which are not established in the countries that fall under the criteria above will be ineligible.

For the duly justified and exceptional reasons listed above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or a non-eligible country entity, shall not participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 73 .

Expected Outcome:

1.Enhanced knowledge base of secondary raw materials in the EU and third countries, including their potential, resource estimation, production, refining processes and biodiversity footprint;

2.Accelerated development of projects leading to commercial exploitation of secondary raw materials in the EU;

3.Developed reports analysing future trends in raw materials markets.

4.Identified supply and demand bottlenecks of future secondary raw materials supply;

5.Improved EU raw materials intelligence, strategic planning and foresight capacity.

Scope: A successful transition to a climate-neutral, biodiversity friendly, circular and digitised EU economy relies heavily on a secure supply of raw materials. In order to strengthen EU autonomy and reduce over-dependency, we must boost domestic sourcing, both for primary and secondary raw materials.

Actions should be based on a common understanding of relevant terms and codes, and develop an understanding of anthropogenic resources and derive the needed aspects for classification of recovery projects and to develop criteria for a transparent, consistent and objective classification, needed to establish a comprehensive resource classification approach.

Projects should also include the biodiversity footprint of primary and secondary raw materials in the expected reports and foresights, using natural capital accounting frameworks.

Actions should acquire new data on secondary raw materials via in situ sampling from different regions across the EU, collect existing data and present in a harmonised UNFC format. The monitoring should focus on countries where the waste goes into European recycling industrial ecosystems. However, the monitoring must cover the statistics of wastes exported from Europe as well as waste flows between Member States. The action could build on and advance further the work of UNECE – UNFC expert group on Anthropogenic resources regarding the classification of secondary raw materials and the work of Horizon Europe project FUTURAM regarding collection of data and information on secondary raw materials. Projects could build on the knowledge and models from projects funded under HORIZON-CL6-2021-BIODIV-01-15, as well as the UN WCMC natural capital accounting frameworks. 74 The action should develop a proposal for EU statistics for secondary raw materials.

The action should focus on the following streams of secondary raw materials, with particular attention to critical raw materials: waste batteries, WEEE, mining waste, slags and ashes, and construction and demolition waste. The action should also anticipate the evolution of WEEE directive.

All the data and information generated through these actions should be shared in open formats on a free of charge basis with the European Commission, for its own use and for publication.

The action should envisage clustering activities with other relevant selected projects for cross-projects co-operation, consultations and joint activities on cross-cutting issues and share of results as well as participating in joint meetings and communication events. To this end proposals should foresee a dedicated work package and/or task, and earmark the appropriate resources accordingly.

International cooperation is encouraged with countries with which the EU has signed Strategic Partnerships on raw materials, especially with Ukraine. 75

HORIZON-CL4-2026-01-MAT-PROD-14: Improving availability of secondary raw materials through recycling (IA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 7.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 28.00 million.

Type of Action

Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

To increase EU resilience in raw materials supply chains and thus reduce the serious risk to the Union's strategic assets, economic and societal interests, autonomy and security associated with the current EU reliance on a few third countries for critical raw materials, by increasing sustainable and responsible sourcing of primary and secondary raw materials necessary to enable the green and digital transition and in alignment with the objectives of the Critical Raw Materials Act 76 , participation in this topic is limited to legal entities established in Member States, associated countries, OECD countries, African Union Member States, MERCOSUR, CARIFORUM, Andean Community and countries with which the EU has concluded strategic partnerships on raw materials 77 as well as trade agreements (or association/economic partnership or equivalent agreements, including the new Clean Trade and Investment Partnerships) containing raw materials cooperation provisions (i.e. Energy and Raw materials chapters) 78 . The choice of these countries was made taking into consideration the development of strategic international partnerships on raw materials and avoidance of reinforcing existing over-dependencies, as well as the importance of involving partners committed to pursuing open trade in such materials.

Proposals including legal entities which are not established in the countries that fall under the criteria above will be ineligible.

For the duly justified and exceptional reasons listed above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or a non-eligible country entity, shall not participate in the action.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.Raw materials recycling and re-use of components and/or products from end-of-life products technologies and urban mines, including cost-effective and efficient disassembly, separation, shredding and sorting technologies for separation and recycling and the sustainable embedment of the process regarding energy, resource and water efficiency;

2.Projects should analyse impacts on biodiversity of urban mines and subsequently propose solutions for reducing these impacts with the aim of renaturing these sites;

3.Improved responsible supply of raw materials to Europe contributing to the Critical Raw Materials Act (CRMA) 79 objectives (Article 1).

Scope: The focus is on raw materials (metals only), particularly on critical raw materials.

Actions should demonstrate new or improved systems located in the EU developing material efficient high-quality recycling of raw materials, improved resource efficiency and reduced impacts on biodiversity.

Actions should focus on the whole chain of recycling processes and procedures - from collection, logistics, characterisation, disassembly, separation, shredding, sorting, cleaning, refining, purification of secondary raw materials and quality of produced outputs, ending with renaturation of urban mines or waste deposits.

Recycling and re-use where the recycled material is of lower quality and functionality than the original material (downcycling), is not in the scope of the topic.

The recycling industry based in the EU, and users of recovered secondary raw materials should assume a prominent role in the proposed actions, supported by adequate allocation of resources.

Actions should envisage clustering activities with other projects aiming at bioremediation second life, re-use, repurposing, remanufacturing of products and/or components relevant selected projects for cross-projects co-operation, consultations and joint activities on cross-cutting issues and share of results as well as participating in joint meetings and communication events. To this end proposals should foresee a dedicated work package and/or task, and earmark the appropriate resources accordingly.

Proposals submitted under this topic must include a business case and a credible exploitation strategy, covering all required elements as outlined in the introduction to this Destination. For TRLs 6-7, a credible strategy to achieve future full-scale deployment in the EU is expected, indicating the commitments of the industrial partners after the end of the project.

International cooperation is encouraged with countries with which the EU has signed Strategic Partnerships on raw materials, especially with Ukraine. 80

HORIZON-CL4-2027-01-MAT-PROD-16: Technologies for innovative processing of raw materials (IA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 10.00 and 12.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 49.00 million.

Type of Action

Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit in part B of the General Annexes is exceptionally extended by 3 pages.

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

To increase EU resilience in raw materials supply chains and thus reduce the serious risk to the Union's strategic assets, economic and societal interests, autonomy and security associated with the current EU reliance on a few third countries for critical raw materials, by increasing sustainable and responsible sourcing of primary and secondary raw materials necessary to enable the green and digital transition and in alignment with the objectives of the Critical Raw Materials Act 81 , participation in this topic is limited to legal entities established in Member States, associated countries, OECD countries, African Union Member States, MERCOSUR, CARIFORUM, Andean Community and countries with which the EU has concluded strategic partnerships on raw materials 82 as well as trade agreements (or association/economic partnership or equivalent agreements, including the new Clean Trade and Investment Partnerships) containing raw materials cooperation provisions (i.e. Energy and Raw materials chapters) 83 . The choice of these countries was made taking into consideration the development of strategic international partnerships on raw materials and avoidance of reinforcing existing over-dependencies, as well as the importance of involving partners committed to pursuing open trade in such materials.

Proposals including legal entities which are not established in the countries that fall under the criteria above will be ineligible.

For the duly justified and exceptional reasons listed above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or a non-eligible country entity, shall not participate in the action.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome:

1.Increased recovery rates of valuable raw materials, particularly critical raw materials from low grade or complex ores and/or from mining waste;

2.Increased economic performance in terms of higher material-, water-, energy- and cost-efficiency and flexibility in minerals processing and metallurgical processes; and

3.Improved health, safety and environmental performance of the operations throughout the whole life cycle that is considered, including a reduction in waste, wastewater and generation of emissions of air pollutants and a better recovery of resources from generated waste, reducing the environmental footprint and contributing to biodiversity and ecosystems preservation.

Scope: Actions should develop and validate / demonstrate pilot scale facility located in the EU integrating relevant processing and refining technologies for improved recovery of raw materials from low grade and/or complex ores from extractive wastes, reduction of waste and water and air pollution, higher energy efficiency and reduction of land and sea-use change, habitat loss, degradation and fragmentation. The action can also focus on reducing the content of toxic elements or compounds in the resulting material products. The actions should target minerals and metals, particularly critical raw materials.

The solution proposed should be flexible enough to adapt to different or variable ore grades and extractive waste streams and should be supported by efficient and robust process control. Where relevant, any solution proposed for the reduction of the content of toxic elements or compounds in the resulting materials should also include the appropriate management of the hazardous substances removed.

Actions should develop intelligent and innovative production systems which better utilise natural resources by minimising losses during waste-rock separation in an optimised and energy-efficient process and by minimising use of water.

Recycling of end-of-life products is excluded from this topic.

Actions should envisage clustering activities with other relevant selected projects for cross-projects co-operation, consultations and joint activities on cross-cutting issues and share of results as well as participating in joint meetings and communication events. To this end proposals should foresee a dedicated work package and/or task, and earmark the appropriate resources accordingly.

Actions should facilitate the market uptake of solutions developed through industrially- and user-driven multidisciplinary consortia covering the relevant value chain and should consider standardisation aspects when relevant. The action should also include the analysis of financial opportunities ensuring the market exploitation and replication of the circular business model behind the developed solutions as new processes, products and/or services. The industry based in the EU, and users of recovered secondary raw materials should assume prominent role in the proposed actions, supported by adequate allocation of resources.

Proposals submitted under this topic should include a business case and exploitation strategy, as outlined in the introduction to this Destination. For TRLs 6-7, a credible strategy to achieve full-scale deployment in the EU is expected, indicating the commitments of the leading partners after the end of the project.

International cooperation is encouraged with countries with which the EU has signed Strategic Partnerships on raw materials, especially with Ukraine. 84

HORIZON-CL4-2027-01-MAT-PROD-17: Expert network on Critical raw materials (CSA)

Call: INDUSTRY

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

To increase EU resilience in raw materials supply chains and thus reduce the serious risk to the Union's strategic assets, economic and societal interests, autonomy and security associated with the current EU reliance on a few third countries for critical raw materials, by increasing sustainable and responsible sourcing of primary and secondary raw materials necessary to enable the green and digital transition and in alignment with the objectives of the Critical Raw Materials Act 85 , participation in this topic is limited to legal entities established in Member States, associated countries, OECD countries, African Union Member States, MERCOSUR, CARIFORUM, Andean Community and countries with which the EU has concluded strategic partnerships on raw materials 86 as well as trade agreements (or association/economic partnership or equivalent agreements, including the new Clean Trade and Investment Partnerships) containing raw materials cooperation provisions (i.e. Energy and Raw materials chapters) 87 . The choice of these countries was made taking into consideration the development of strategic international partnerships on raw materials and avoidance of reinforcing existing over-dependencies, as well as the importance of involving partners committed to pursuing open trade in such materials.

Proposals including legal entities which are not established in the countries that fall under the criteria above will be ineligible.

For the duly justified and exceptional reasons listed above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or a non-eligible country entity, shall not participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 88 .

Expected Outcome:

1.Strengthening the expert capacity in the EU in a wide range of raw materials along the whole value chain;

2.Better informed and more effective decision-making by the EU and National policy makers and the producers and users of raw materials regarding the supply and demand of raw materials and the associated environmental and social aspects;

3.Improved EU official statistics and building the EU knowledge base of primary and secondary raw materials.

Scope: Actions should strengthen an EU expert network and community covering all raw materials screened in the critical raw materials assessment of 2027. Flexibility in screening additional raw materials will be an added value.

The consortium should build the EU expert community covering each screened raw material with expertise on primary and secondary resources; production, including exploration, mining, processing, recycling and refining; substitution of critical raw materials; raw materials markets; future demand and supply; supply risk management and stress tests; materials flows; raw materials standardisation; environmental footprint, socio-economic analysis, and strategic value chains and end-use sectors, including batteries, e-mobility, renewable energy, electronics, security and aerospace.

The actions should contribute to the EU policy making related to critical raw materials, in particular to the implementation of the Critical Raw Materials Act, including the development of the new list of critical raw materials and their specific applications or sectors. The action is expected to coordinate with the Commission regarding the events and reflect the EU policy planning.

The actions should also improve data and knowledge on all screened raw materials and the analysis of the future supply and demand of raw materials, their environmental footprint, technology gaps and innovation potential along the raw materials value chains.

The action should update the data and information fact sheets from the previous criticality exercise for all screened raw materials, and ensure their quality by relevant raw material experts. Factsheets are to be finalised by the end of 2029, and could be fine-tuned before publication expected in 2030.

The action is expected to organise two expert validation workshops in 2029 to support the EU criticality assessment, and validate draft factsheets for all screened materials. In coordination with the Commission, organise in-depth workshops on several strategic metals for renewable energy, e-mobility and aero-space and security / dual use, with recognised commodity experts from industry and other organisations.

The data and information produced by the action shall be shared with the Commission at free of charge basis.

The action should envisage clustering activities with other relevant selected projects for cross-projects co-operation, consultations and joint activities on cross-cutting issues and share of results as well as participating in joint meetings and communication events. To this end proposals should foresee a dedicated work package and/or task, and earmark the appropriate resources accordingly.

Innovative Advanced Materials-based Technologies

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-05-MAT-PROD-25: New or enhanced Innovative Advanced Materials (IAM) enabled sensing functionality (RIA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 7.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 22.50 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Technology Readiness Level

Activities are expected to start at TRL 3 and achieve TRL 5-6 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering the two areas described below, grants will be awarded to applications not only in order of ranking but at least also to one proposal that is the highest ranked within each area, provided that the applications attain all thresholds. For the purposes of the ranking the main area declared by the proposal will be considered.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 89 .

Expected Outcome:

1.New technological solutions with improved performance and reduced energy and environmental impact consumption providing significant advances towards the emergence of competitive value chains in IAM-based sensing components in Europe.

2.Widespread adoption of low-cost IAM-based sensing solutions in e.g. environmental monitoring, industrial safety, and next-generation smart sensing applications including health monitoring.

Scope: Proposals should address at least one of the following two areas.

A. IAM-enabled multifunctional surfaces able to detect and respond to changes in the environment, such as temperature, pH, moisture, microbiological or chemical pollutants, concentration of chemical species in air, gases and liquids, and converting these signals into measurable outputs. Such surfaces should demonstrate high performance in terms of sensitivity, selectivity, response time, durability and cost-effectiveness. Proposals should target applications such as environmental and ecosystems monitoring, as well as health monitoring.

B. The development of enhanced IAM-based sensor demonstrators, that enable miniaturization and integration into application systems e.g. into portable IoT devices, lightweight wearables and wearable systems. These sensors must meet key performance requirements, e.g. compatibility with silicon technology, operation in real conditions with low power consumption, high sensitivity (low limit of detection and/or high signal to noise ratio), high selectivity and fast detection speed.

Stability and resistance to extreme conditions such temperature and humidity should be taken into account. Solutions could also take inspiration from bio-mimicry.

Proposals may contribute to one or both above R&I areas. However the main area addressed must be clearly and unambiguously identified in the proposed project.

Proposals should integrate the value chain and incorporate the relevant manufacturing technologies needed to bring the developed devices towards the market.

Technology must be demonstrated in an industrially relevant environment.

Proposals should include activities aiming at facilitating future exploitation of results.

Consideration of circularity and recyclability, and compliance with the safe and sustainable by design framework should boost the confidence of industry and end-users and enhance the Innovative Advanced Materials ecosystem and uptake.

Where relevant, cooperation with activities funded under the Chips Joint Undertaking, the photonics partnership or other initiatives are encouraged.

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

This topic implements the co-programmed European Partnership Innovative Advanced Materials for the EU (IAM4EU).

Destination: Developing an agile and secure single market and infrastructure for data-services and trustworthy artificial intelligence services

Developing an agile and secure single market for data and trustworthy AI services is central to Europe’s digital sovereignty and competitiveness. The convergence of the Telco-Edge-Cloud continuum (3C) with open orchestration platforms will unlock the transformative potential of AI across strategic sectors, from mobility and energy to health and manufacturing, fostering new services and business models. Building a sovereign Open Internet Stack, rooted in open-source, interoperable and standard-based solutions, will reinforce trust, resilience and innovation, while ensuring Europe retains control over critical digital infrastructures. At the same time, decentralised and federated approaches to AI data processing, combined with breakthroughs in sustainable data centres, will help overcome Europe’s compute bottlenecks and dependencies, and reduce the environmental footprint of AI. By aligning with the Data Union Strategy and Common European Data Spaces, these efforts will deliver secure, compliant and adaptive data-sharing frameworks that empower citizens, businesses and administrations. Together, they will strengthen Europe’s ability to innovate, scale and lead globally in data and AI, anchoring digital sovereignty in line with EU values and strategic interests.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

Telco-Edge-Cloud continuum/ 3C Network (Connected Collaborative Computing) and Open Internet Stack

Proposals are invited against the following topic(s):

HORIZON-CL4-2027-04-DATA-08: Demand-side 3C pilot demonstrators on converged Telco Edge Cloud Infrastructure (IA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 19.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 38.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 90 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 91

Technology Readiness Level

Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Expected Outcome:

1.Demand-side driven validation of open orchestration platforms across the telco-cloud edge continuum unlocking notably the transformative value of AI for European businesses, driving business growth in multiple industries strategic for Europe.

2.Enabling the path towards sustainability and competitiveness of key vertical sectors in the EU, exploiting the innovative features of 3C/ telco-edge-cloud, including network features such as API (Application Program Interface) aggregation, slicing, automation, latency, security, ISAC (Integrated Sensing and Communication), reconfigurability, to significantly improve quality of service, resilience, sustainability and other performance parameters of digital communications.

3.The demand pilots will have a clear sector relevance, with one pilot addressing the future of smart mobility including the automotive sector.

4.A vibrant ecosystem around 3C/telco-edge-cloud infrastructure, targeting SMEs and start-ups to develop innovative services and new business models validation and marketplace exploitation strategies, as well as paths to commercialization or replicability.

Scope: The term “Connected, Collaborative, Computing (3C) Network” refers to a telco-edge-cloud, secure multi-provider and multi-technology, communication system that hosts network functions and workloads for and beyond connectivity (e.g. 6G, AI Storage/Compute, networking, Security ISAC , and any other application or capability) as a service (aaS). Key features of the 3C/ telco-edge-cloud network include programmability, fast service creation, security and privacy, mobility, and service continuity across inter-domain deployments. 3C/ telco-edge-cloud networks enable innovative use cases for an EU Digital Market that integrate communication, collaboration and computing capabilities in competitive and sustainable business models that will reinforce EU competitiveness and contribute to digital sovereignty, in particular through the use of Open Internet Stack components. Resulting solutions should be available for use in the public sector (for instance for justice systems).

The 3C Network large-scale pilot funded under topic HORIZON-CL4-2025-03-DATA-08: Large-scale pilots for supply end-to-end infrastructures integrating device, network computing and communication capabilities for Telco Edge Cloud deployments, as a basis for Connected Collaborative Computing Networks (3C networks) (RIA) is setting up end-to-end integrated infrastructures and platforms, bringing together players from different segments of the connectivity and compute value chain and beyond. The main target is to research and validate the integration of device, network, cloud and edge computing, and communication capabilities for telco edge cloud deployments to realize a ubiquitous mesh of computing and communication resources. As a main outcome the supply side pilot establishes an open orchestration platform across the telco-cloud-edge continuum, exploits the transformative value of AI and builds on the integration of solutions developed by the Open Euro Stack.

Demand- side pilot demonstrators called in this topic will build on the above supply side large-scale pilot and integrate future domain-specific applications and services with an emerging European 3Cs/ telco-edge-cloud infrastructure, leveraging different network features. Key features will include security and privacy solutions offering resistance to emerging quantum threats (such as via post-quantum cryptography), mobility, and service continuity across inter-domain and multi-cloud deployments and ecosystems.

Up to two pilot demonstrators on below listed specific verticals are expected.

1.One pilot demonstrator focusing on Mobility covering specific areas of transport, logistics and the Automotive industry. The pilot should support the strategy as developed by the Connected and Autonomous Vehicle Alliance identified in the Automotive Action plan , in particular Pillars 3 (AI models) and 5 (Large-scale testing), which will be launched in 2025.

2.One pilot demonstrator focusing on another vertical sector such as energy, smart communities, industrial virtual worlds, health, agrifood or manufacturing.

They would be driven by a consortium including partners both from the demand (user) and infrastructure supply side. The pilot demonstrators should take advantage of open application interfaces, explore the possibilities of AI, “virtual worlds”, and other innovative technologies for practical implementation in the referred vertical domains. They should leverage combined investments in network infrastructure, computing and connectivity infrastructure as an enabler for more extensive set of digital innovation, with cognitive cloud computing and swarm intelligence, generative AI and LLM, as well as on-boarding of XR/AR technologies, being ranked most important.

Proposals are expected to detail a robust data governance model for the data generated and processed within the pilots. This model should address data sovereignty, interoperability with Common European Data Spaces, and alignment with principles from initiatives like Gaia-X. It should outline clear mechanisms for secure and compliant data sharing between the demand-side (users) and supply-side (infrastructure providers), establishing the trust necessary for a functional data economy on top of the 3C infrastructure.

Pilot demonstrators should demonstrate the evolution from virtualised and cloud-native network functions towards automated network operations enabling agile and green IoT-edge computing solutions and decentralised intelligence. They should also demonstrate benefits for infrastructure providers to operate networks more efficiently and move beyond traditional connectivity-service models to higher value-added services.

Demonstrations will respond to the ever more demanding processing power of AI through integration on-device level and changes triggered by GenAI affecting global communication infrastructures. Orchestration of workloads across the telco-cloud-edge continuum from distributed sensors and actuators to the edge and cloud is a crucial part of innovation as AI becomes more resource-intensive.

The pilot demonstrators should take into consideration the recommendations on user requirements from the advisory group of end users, as well as liaise with the collaboration and support action (CSA) funded under WP25 to bridge between the 3C/ telco-edge-cloud supply pilot funded under WP25 and the demand pilots funded under WP26-27.

The pilots should exploit in particular open APIs and open-source components as developed by the supply side pilot, e.g. including the use of capabilities to implement specific communication management services (e.g. Open RAN security, RIC VNF…), up-take of existing standards and relevant open-source projects (e.g., Sylva, ANUKET, Nephio, CAMARA, etc.).

The pilot demonstrators should include testing, validation and demonstration of prototypes of agile virtualised network functions combined with ubiquitous mesh of integrated devices, computing and communication resources in operational environments, ensuring security and privacy, protection also in the face of emerging quantum threats, energy efficiency, transparency and control of the ecological footprint, as well as sustainable artificial intelligence services.

The pilot demonstrators are expected to re-use as far as possible existing open-source frameworks, i.e. open-source software governed by communities of contributors, that will provide key technology components for the operation of the 3C/ telco-edge-cloud supply-side large scale pilot. These open-source frameworks should be made available to the Open Internet Stack Support for Scale.

The proposals should ensure a high degree of participation of stakeholders from the relevant vertical sectors, with a particular attention to the involvement of SMEs, scale-ups and start-ups.

The pilots should establish a high degree of relations and collaborate with complementary EU funded research activities, like the Smart Networks and Systems Joint Undertaking (SNS JU) projects, the “Empowering AI across the continuum” and the “Sovereign edge/cloud infrastructure” R&I areas, the PPP virtual worlds, CCAM partnership as well as support of SW-defined vehicle initiative under the Chips JU.

HORIZON-CL4-2026-04-DATA-02: Open Internet Stack Sovereign Solutions (RIA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 7.00 and 10.25 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 20.50 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Beneficiaries may provide financial support to third parties (FSTP). The support to third parties can only be provided in the form of grants. The maximum amount to be granted to each third party is EUR 400 000 to allow 1/ cases where a given legal entity may receive FSTP under several grants (e.g. from different calls) 2/ reaching the maturity level for third party’s project to ensure sustainability with multiple awards. FSTP may comprise up to a maximum of 80% of the total requested EU contribution.

Expected Outcome: The overall expected outcome is a large selection of Open-Source solutions that will be organised under the Open Internet Stack framework built under WP 2025. This will address the needs of both supply and demand side of the rich and diverse eco-system of 3C European providers and verticals. This topic will stimulate the emergence at European and global scale of solutions that are:

1.Open source and made in Europe, supporting trust, and sovereignty, and delivering credible alternative choices for citizens, governments and companies including start-ups and SMEs.

2.Paced for easy deployment by the rich European eco-systems of providers, integrators and verticals.

3.Interoperable, standard-based, decentralised solutions for enabling network effect.

Scope: Proposals should address one or several of the following technology areas:

1.Network and Transport technologies including for example routing and virtual private networks, survivable mesh technologies.

2.Sovereign operating systems and firmware (including smartphones).

3.Open Source software productivity and supply chain technologies such as federated forges, independent and cross-platform development framework.

Applicants should devise a plan for ensuring that the solutions are designed for efficient deployment, with pre-configured, modular components that facilitate integration by a wide range of users, including SMEs, public administrations, research and education and service providers.

Applicants should detail development, integration, testing, deployment, uptake and operation activities. Focus will be on Open Source solutions and their integration and adoption in vertical use cases, to ensure replicability of the results and portability in different areas.

Proposals are expected to demonstrate:

1.That the proposed solution(s) has(ve) the technical maturity in terms of scalability, resiliency, advanced cryptographic protection (e.g. against emerging quantum threats via post-quantum cryptography), alignment with standards including for software and hardware supply chain and efficiency including environmental.

2.That there is a community with critical mass that actively supports the development with or without associated business model.

3.Evidence of use cases, interest and engagement from users and deployers of the solution.

4.Credible path to be part of the Open Internet Stack in terms of cataloguing, searchability, availability through app-stores and alignment with EU regulation.

Applicants should detail any relevant previous projects on which the project will expand.

Applicants should detail their plan to creating synergies with other topics such as those in the WP25 Open Internet Stack, 3C, Virtual Worlds/Web4.0 as well as like-minded initiatives on the same solution perimeter.

Proposals should also detail their strategy for maintenance, cataloguing, marketing, communication as well as the relationship with to the “Open Internet Stack Support for Scale” topic.

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

Financial support to third parties

If applicants opt for financial support to third parties, they should primarily target calls towards internet innovators and adopters of Open Source technologies. Applicants should provide the programme logic for the third-party projects, managing the projects lifecycle, and provide the necessary technical and non-technical support: these tasks cannot be implemented using the budget earmarked for the financial support to third parties.

HORIZON-CL4-2026-04-DATA-03: Open Internet Stack Support for Scale (CSA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 4.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 92 .

Expected Outcome: Projects results are expected to contribute to all the following outcomes:

1.A common approach and hub for cataloguing, packaging, reviewing and validating Open Internet Stack components and projects.

2.Long term viability by advising on Open Source sustainability and maintenance models including business and foundation; Promotion of the EU and Associated Countries as ideal location for Open Source Foundation sieges.

3.A common branding, marketing, training and communication plan ensuring consistent perception and scale-up.

A close interleave with policy development through a dedicated policy sandbox.

Scope: Applicants should devise a plan for:

1.Cataloguing solutions in a structured and easy to discover way

2.Performing security and accessibility audits on the selected solutions under the Open Internet Stack.

3.Screening and selecting European funded Open Source projects, including by exploring the relevant Horizon Europe programmes, and devising a strategy for the Open Internet Stack to become a central hub for those solutions.

4.Establishing links and mutual support with national, multi-country and pan-European initiatives supporting Open Source sovereign solutions.

5.Advising on sustainability models (both for and non-for profit), on standardisation, licencing schemes, or localisation/internationalisation

6.Elaborating a common branding with associated marketing and communication tool

7.Developing training material on these solutions that stresses their value in terms of EU legislation compliance (GDRP, DSA/DMA, CRA…), security (e.g. reference to security audits, list of dependencies), use cases, funding/business model, deployment requirements (server side, user side), link to repository and community resource (maintainers, community manager, discussion board…). Training material will be tailored to each target audience: Operators of infrastructure, Integrators, Government & verticals IT, end users.

8.Implementing measures to identify/attract technology adopters (e.g. services providers, integrators, OSPOs in governments/verticals) to become promoters of these technologies.

9.Developing sandbox tools for ensuring smooth compliance-by-design of the Open Internet Stack with relevant existing or futures EU policies.

10.Supporting Open Source awards scheme and sustainability models after the action is finished.

We consider that proposals with an overall duration of typically 36 months would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other durations.

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

Achieving the end-to-end AI compute continuum

Proposals are invited against the following topic(s):

HORIZON-CL4-2027-04-DATA-03: New approaches for decentralized, federated and sustainable AI data processing (RIA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 17.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 35.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 93 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 94

Technology Readiness Level

Activities are expected to start at TRL 3 and achieve TRL 6-7 by the end of the project – see General Annex B.

Expected Outcome: Project results are expected to contribute to developing new approaches, tools and techniques that overcome the obstacles of today's centralised AI compute techniques: limits in the availability of energy and AI compute capacity in centralised standalone environments, limited availability of types of AI chips, data quality and security and latency in AI data processing. The ultimate objective is to help overcome EU’s AI compute capacity bottlenecks by offering alternative decentralised and sustainable AI compute models that enable exploitation of diverse hardware processing architectures and scaling approaches.

Scope: This topic focusses on technologies and techniques that enable AI data processing to leverage distributed compute resources across the cloud and edge computing continuum throughout the whole AI model lifecycle from data collection, training, fine-tuning, and deployment. To overpass today’s state of the art in the area, the considered research areas include:

1.To research on distributed, decentralised, and federated “compute continuum” enabled AI architectures beyond federated learning and integrating model compression tools and new mechanisms to enable AI data processing to scale across multiple and diverse computing infrastructures.

2.Development, deployment, and operation of AI workflows across heterogeneous and distributed infrastructures along the compute continuum (edge, cloud, HPC), including the possibility of incorporating innovative computing paradigms (neuromorphic and quantum computing) and hardware efficiency enhancements ((e.g., including in-memory computing, and hardware and software approximation).

3.Novel methods and techniques to improve data availability and consistency for decentralised AI data processing. These consider tools to ensure data quality (e.g. prevention of data sets imbalance or inconsistency across distributed data sources), volume optimisation for data transfers across environments, and distributed data management, all while preserving data privacy and preventing data leaks (e.g. via advanced cryptographic protection such as post-quantum cryptography for resistance to emerging quantum threats).

4.New tools and mechanisms to measure, monitor and improve end-to-end energy efficiency and sustainability of AI data processing across the compute continuum, including the exploration of energy and sustainability implications of the heterogeneous AI processing architectures and their impact in the compute infrastructure design and long-term sustainability.

Successful project proposals should showcase proposed developments in at least two complementary use cases in different domains. These use cases should demonstrate the value gained and potential impact of project achievements in real-world situations, as well as address key applications and sectors critical to Europe's competitiveness. Use cases should provide compelling examples and scenarios and cater for the reproducibility of results' added value and impact in additional economic sectors.

HORIZON-CL4-2027-04-DATA-09: Energy efficiency and sustainability of AI data processing in Data Centres (IA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 39.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action.

Subject to restrictions for the protection of European communication networks.

Technology Readiness Level

Activities are expected to start at TRL 6-7 and achieve TRL 8 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio coverage, grants will be awarded to applications not only in order of ranking, but also to at least three proposals addressing expected outcomes 1-3 (improve heat removal from high-power AI, novel backup power systems and data centre optimisation for energy-efficient AI processing) and one proposal focussed on offering an open pilot demonstration site, subject to proposals passing all evaluation thresholds.

Expected Outcome: Pilots for new technologies and a demonstration site which contribute to energy-efficient and sustainable AI data processing in data centres, reinforcing EU strategic autonomy and climate goals. Project results are expected to contribute to one or more of the following outcomes (see more details in scope):

1.Demonstrated innovations that substantially improve heat removal from high-power AI chips (e.g. direct on-chip cooling, advanced thermal interface materials, multi-scale thermal management), enabling higher performance without thermal throttling. This should lead to lower cooling energy needs and higher reliability for dense AI workloads.

2.Prototypes of novel backup power systems (such as graphene-enhanced batteries) that operate with minimal cooling requirements, improving data centre resilience and enabling better use of renewable power.

3.New methods and frameworks that optimise the entire data centre for energy-efficient AI processing. This includes intelligent workload scheduling and AI model optimisation techniques to reduce energy use (e.g. carbon-aware job scheduling and power capping to cut energy demand and peak temperatures), as well as designs for integrating on-site/off-site renewables and waste-heat reuse.

4.As a result of all the above bullet points, an open pilot demonstration site that allows for the testing and integration of the outcomes of these projects and serves as the European reference for showcasing the breakthroughs and cutting-edge technologies for energy-efficient and sustainable data centres developed under this topic. This site should serve as a model for technology uptake for the European data centre industry.

Outcomes should demonstrate potential for improved power usage effectiveness and utilisation of waste heat in external applications, aligned with European targets for carbon-neutral heating/cooling.

Scope: Actions should address the following development areas:

1.Direct on-chip cooling and thermal management, including novel and innovative cooling techniques applied at chip and module level (direct liquid cooling, heat spreaders, thermal interface materials, and advanced packaging) and multi-scale thermal management techniques.

2.Energy-efficient power backup and storage systems: Innovations in early-stage energy storage concepts (graphene-enhanced batteries, supercapacitors, and other emerging battery chemistries) and approaches for net-zero backup.

3.Sustainable data centre architectures and AI workload optimization: addressing AI-driven workload scheduling, adaptive power management, dynamic resource allocation and integration of data centre heat capture and reuse.

4.Materials research for energy efficiency: Projects to make use of existing research in new materials and components supporting energy efficiency and thermal management, and to employ these for data centres benefit.

5.Optimisation of data centre operation and functioning: explore AI solutions to optimize the Data centre functioning, computing architecture, and virtualization, minimizing its carbon and environmental footprint.

6.Integration of data centres into energy systems and the wider region: including solutions that integrate Data centres into energy system planning and operation.

Aside from these, the pilot demonstration site must allow to combine the outcomes supplied by the other funded projects in the topic and enable for showcasing, benchmarking, and promoting their results across interested industrial stakeholders, including the European data centre and collocation industry, as well as other AI data centre operators, such as cloud and edge computing providers.

Overall, this topic is expected to fund four projects. Three projects are expected to address expected outcomes 1-3, while a fourth project is expected for expected outcome 4 (the open pilot demonstration site). For projects addressing expected outcomes 1-3 at least two use cases should showcase each project results.

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

Projects funded under this topic are encouraged to build synergies and leverage their outcomes with funded projects from Cluster 5 HORIZON-CL5-2027-05-D4-06: Thermal energy optimisation and waste heat recovery of high energy demand IT rooms in buildings or small edge data centres.

Data (under AI, Data and Robotics partnership)

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-04-DATA-06: Efficient and compliant access to and use of data (IA) (AI, Data and Robotics partnership)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 11.50 and 23.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 46.50 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The conditions are described in General Annex B. The following exceptions apply: In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway, associated countries and OECD countries.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or a non-eligible country entity, shall not participate in the action.

Technology Readiness Level

Activities are expected to start at TRL 6-7 and achieve TRL 8 by the end of the project – see General Annex B.

Expected Outcome: Project results are expected to contribute to the following outcomes:

1.Lead to the development of secure, compliant and adaptive systems that improve the availability, accuracy, privacy and interoperability of data across the Union.

2.Deliver advanced, AI-driven compliance technologies and regulatory tools that reduce administrative burdens, promote regulatory efficiency, and facilitate the implementation of the Data Union Strategy, a Single Market for data, Common European Data Spaces, the European Business Wallet, and the Digital Justice Strategy for 2025-2030.

3.Enable more agile regulatory processes, foster mutual recognition of compliance efforts across borders and cross-border cooperation, support interoperability between Member States, and enhance transparency and trust. They will position the Union at the forefront of regulatory innovation, while strengthening the functioning, resilience, competitiveness, and digital leadership of the Single Market.

4.Enhance the excellence and competitiveness of companies, professionals, and public administrations by providing innovative, automated solutions to navigate and comply with Union rules seamlessly across borders.

5.Enhance public services and strengthen the competitiveness and digital sovereignty of the EU by improved availability and use of high-quality real and synthetic data to train AI systems more effectively.

Scope: The scope of this topic is to support the deployment of secure, interoperable, and scalable data management systems, ensuring seamless cross-sector data integration, automation of key processes, and compliance with EU frameworks.

The actions should deliver high-quality, well-structured, secure and compliant data, tailored to evolving societal, industrial, research and public sector needs, underpinning key EU strategies, including the Data Union Strategy, the Apply AI Strategy, the Digital Justice Strategy, and the development of Common European Data Spaces, Data Labs and EuroHPC systems (including the AI Factories). The developed methods, technologies and tools should ensure that data is effectively shared between sectors, disciplines, and participating countries, and that the data is reliable, traceable, and fit for purpose.

The proposal should clearly state (in the abstract and in the introduction) which of the following two areas it addresses. A proposal can address both areas, but it should indicate one of them as the main focus of the proposal, as it will be evaluated accordingly under that area:

1.Area 1: The actions under this area should support the development and deployment of advanced, AI-driven compliance technologies and solutions that automate data transactions and key regulatory processes, reduce administrative burdens, and facilitate seamless adherence to EU rules. This includes RegTech/GovTech//LegalTech applications such as digital tools offering real-time compliance guidance, automated rule-drafting assistants for policymakers, and multilingual chatbots providing regulatory support to businesses and professionals. Predictive analytics and risk-based approaches should allow tailored compliance pathways, while integration with national systems and the Single Digital Gateway should promote cross-border mutual recognition and application of the Once-Only Principle. Public administrations should be equipped with automated compliance assessment tools, real-time analytics dashboards, and interoperability frameworks to enhance and streamline regulatory oversight and cooperation. The technologies and solutions should contribute to the principles of fairness, accountability and transparency in AI-driven compliance solutions, including traceability and explainability of automated actions.

2.The solutions under Area 1 should adhere to open technical standards, ensuring scalability, inclusiveness, and co-development with private and public stakeholders. Robust cybersecurity, trustworthy AI, trust safeguards, security and privacy cryptographic protection, including via post-quantum cryptography, should be embedded, aligning with EU data protection and digital identity frameworks. Artificial intelligence and machine learning models should be harnessed, to the extent possible/reasonable, to enable data-driven feedback loops that support continuous policy learning, allowing regulators to monitor rule implementation, identify unnecessary burdens, and simplify legislation based on real-time evidence. Where appropriate, the actions under this Area should build on and integrate the privacy-enhancing (including anonymization) technologies developed under earlier topics in the Horizon Europe programme.

3.Area 2: The actions under this area should focus on the design and deployment of secure, scalable, and adaptive data management systems that automate key data processes, such as data curation, metadata tagging, ontology management and discovery, labelling, annotation, and quality control, developing and adapting appropriate AI methods and tools for these specific tasks. These systems should facilitate seamless integration and sharing of data across sectors and disciplines, ensuring interoperability, data provenance, data privacy and handling secured against emerging quantum threats via post-quantum cryptography, and compliance with applicable EU legal frameworks. Special emphasis is on enhancing data accuracy, representativeness, and relevance, particularly for use cases in industry, public services, citizen engagement, and the development of trustworthy AI applications, as well as the Common European Data Spaces. The development of such high-quality, semantically rich datasets will be essential to unlock the full potential of AI across domains.

4.Furthermore, the actions under Area 2 may also support the generation and use of high-quality synthetic data, including spatial synthetic data, to complement real-world datasets while preserving data privacy via advanced, state-of-the-art cryptographic protection. This may include, among others, the use of AI-enabled generative graphics pipelines to automate the creation of large-scale simulated environments and the application of parallelised and/or neuromorphic computing techniques to train AI models and artificial agents efficiently.

The actions under both areas should take into account the work of the Data Spaces Support Centre, particularly the blueprint for common European data spaces, and build synergies with related Union initiatives such as AI Factories, European Blockchain Services infrastructure, and the European Business Wallet, as well as with sector-specific Common European Data Spaces, and EU Digital Identity Wallet large scale pilots. Close collaboration with relevant European Partnerships, stakeholders, including industry, public administrations, and research organisations, will ensure that the systems meet the practical needs of data users while fostering innovation, competitiveness, and digital sovereignty within the Single Market.

Destination: Achieving open strategic autonomy in digital and emerging enabling technologies

Leadership in frontier technologies such as Artificial Intelligence, Quantum, Photonics and Semiconductors is essential to Europe’s economic security and global competitiveness. Building on the ambition of becoming the “AI Continent” and in line with the concrete actions devised in the Apply AI Strategy 95 , the EU will consolidate its world-class research ecosystem through initiatives like the RAISE network of AI science labs, the development of safe and efficient frontier AI models, and the deployment of next-generation AI agents and robotics in strategic sectors. In parallel, a long-term quantum strategy will reinforce Europe’s excellence across quantum computing, sensing and communication, supported by new infrastructures and standardisation to secure technological sovereignty. Photonics and semiconductor technologies will remain critical enablers for the digital and green transitions, with investments in advanced integrated photonic devices and resilient semiconductor ecosystems ensuring Europe’s capacity to innovate, scale and compete globally. Foresight and support to emerging materials and technologies will further strengthen Europe’s position at the cutting edge to make sure Europe’s does not miss the emergence of new disruptive technologies, aligning with the Draghi report and the Competitiveness Compass to secure a cohesive, sovereign and future-proof European industrial base.

Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.

AI Continent

AI SCIENCE

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-04-DIGITAL-EMERGING-01: Apply AI: Pilot of the “Science for AI” Pillar of RAISE (“Resource for AI science in Europe”) (RIA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 17.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 17.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Technology Readiness Level

Activities are expected to start at TRL 2 and achieve TRL 4 by the end of the project – see General Annex B.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The following additions to the general award criteria apply:

Quality and Efficiency of Implementation:

1.Scientific Excellence: the scientific excellence of each participant will be assessed based on the scientific credentials of its senior AI researchers. A clear majority (at least 60%) of the participant's senior AI researchers should demonstrate substantial scientific excellence. Examples of evidence for scientific excellence in Artificial Intelligence include, but are not limited to, consistent publications in top-tier venues; significant research impact as reflected by recognised metrics such as the h-index (the number of publications that have each been cited at least that many times); recognized real-world applications; receipt of prestigious awards and substantial competitive grants; membership on editorial boards of leading AI journals; and invited talks at internationally recognized AI conferences.

2.Infrastructure: each participant should possess dedicated premises and infrastructure necessary for high-quality AI research, along with administrative and technical support services.

3.Size: each participant should have at least ten distinct AI research groups. Each research group should typically comprise a minimum of five researchers, including at least one senior AI researcher. Alternative configurations demonstrating equivalent capacity (approximately 50 total dedicated researchers in AI) will also be considered acceptable.

4.Legal Structure: each participant should have the requisite legal framework enabling them to effectively manage personnel, negotiate and execute contracts, and manage intellectual property rights.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: This pilot supports the Apply AI Strategy 96 , particularly its research and innovation efforts, which aims to advance core AI capabilities, especially in frontier AI, and support fundamental AI research. The initiative will pool strategic resources to push the technological frontiers of AI and drive scientific breakthroughs, ensuring that the project contributes to the EU's goal of maintaining European leadership in AI research. Project results are expected to contribute to all of the following expected outcomes:

1.Set up a network of excellent AI Labs in the EU and Associated Countries, raising visibility and strengthening collaboration in European AI research

2.Establish a model of cooperation among these labs and support the development of a strategic research agenda for fundamental research in AI.

3.Ensure that the network operates as a virtual institute across Europe, pooling resources and expertise.

4.Develop synergies with the AI in science efforts in RAISE.

5.Stimulate and support world-class research in AI, both fundamental and applied research. Building on Europe’s research strength, attract collaboration with industry and excellent AI talent.

Scope: Ensuring Europe's technological sovereignty in AI requires reinforcing and leveraging Europe's strengths, particularly its world-class AI research community.

The selected consortium should be composed by leading European AI research institutions. These AI research institutes should be entities with legal structure, dedicated facilities and, a significant number of research teams focusing on AI research. This category also includes multidisciplinary research institutions that host AI-focused branches meeting these criteria. The consortium will pilot a network of excellent European AI research institutes that will collaboratively address fundamental AI research topics, pushing the frontier of the domain. Participants will cooperate within a virtual institute, attracting talents, stimulating industrial initiatives, providing inputs for moonshot projects and developing research agendas for the ones retained by the EC. A substantial share of the project effort should be dedicated to advancing research.

To achieve these objectives, the consortium will undertake a range of dedicated activities:

1.The project will draw an ambitious strategic research agenda towards the next frontier in AI (in 5 years), including explicit targets and milestones;

2.The coordination of the participating institutes and their research in AI will be driven by a world class AI research program. The defined programmes will guide collaborative efforts and ensure a cohesive approach to advancing fundamental AI. Collaboration will, among other, be reinforced by jointly supervised PhDs and Postdocs.

3.The implementation of a world class AI research program, supporting PhDs and Postdocs as well as jointly agreed collaborative research projects, functioning as a distributed "European AI Institute," reflecting the RAISE initiative's long-term vision and enhancing collaboration.

This topic will bring together excellent AI research Institutes in Europe to further develop basic science in AI. Given the importance of such consortium, every participating institution will have to demonstrate its excellence in AI Research through a number of objective criteria.

To ensure openness, during the first year, the project will establish a call for expressions of interest to identify additional leading European AI research labs and individual experts that may collaborate with the project through joint activities or other forms of cooperation to support the expected outcomes and the dedicated activities described in this topic. Proposals should describe the type of actions planned for these collaborations. Appropriate budget and effort should be allocated to ensure that such collaborations complement the network’s expertise and strengthen the implementation of the roadmap.

This initiative will also work in close collaboration with other initiatives in the European AI landscape, such as existing Networks of Excellence, AI societies and associations, and with the fundamental research activities in AI taking place in the horizontal call HORIZON-RAISE and in the EIC pathfinder initiatives to be integrated in RAISE. All proposals are expected to allocate tasks for cohesion activities with the CSA HORIZON-CL4-2025-03-HUMAN-18: GenAI4EU central Hub.

The project selected in this topic should link to the resources offered by the AI Factories and the Data Labs and exploit the various tools offered by the AI-on-demand-platform to share the result and further develop the community.

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

HORIZON-CL4-2027-04-DIGITAL-EMERGING-11: EU Frontier AI Initiative: Developing frontier AI solutions that are safe and computationally efficient within Apply AI (RIA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 44.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 44.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 97 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 98

Technology Readiness Level

Activities are expected to start at TRL 2 and achieve TRL 4 by the end of the project – see General Annex B.

Expected Outcome: The Apply AI Strategy 99 also seeks to bolster EU capabilities and achieve excellence in AI to support the development of European frontier models. As part of the Frontier AI Initiative, which brings together Europe’s leading actors in the field, this topic will support the development of sovereign frontier AI ensuring safety by design. This topic directly contributes to the Apply AI Strategy. Project results are expected to contribute to all of the following expected outcomes:

1.Strengthened European capabilities in the development of frontier AI models.

2.Improved computational efficiency of frontier AI models, resulting in reduced computational costs.

3.Enhanced safety of advanced AI systems based on frontier AI models through the development and implementation of safe-by-design principles and/or AI agents acting as safety evaluators.

Scope: To advance developments of frontier AI models towards highest-level performance, while ensuring energy efficiency, addressing computational constraints, and strengthening safety. The approach of this topic is twofold. First, it aims to advance the AI field through the development and training of a frontier AI model. The AI model should demonstrate state-of-the-art performance, have multimodal capabilities, and be optimized for agentic AI capabilities such as tool use, reasoning, and autonomous problem-solving. Second, this topic supports research on comprehensive methods to reduce the computational demands of frontier AI models and to ensure their safety, including technical methodologies such as automated testing and interpretability.

The primary drivers behind computational efficient AI systems are the urgent challenges posed by the growing energy footprint of AI and current computational limitations. Modern AI models, especially frontier AI models, require substantial computational resources, with a significant impact in the environment. Additionally, they create barriers to entry to those interested in advancing the AI field. Key research areas include compression and distillation techniques aimed at reducing the complexity of large AI models. Innovations in AI architectures are also relevant, with a focus on innovative models that significantly lower computational demands for training and inference. Further, algorithmic approaches aimed at minimizing computational load during pre-training, post-training, and inference can also be considered.

Ensuring the safety of AI systems is essential, especially as AI models become increasingly sophisticated and pervasive. Potential research areas to be considered include addressing misalignment, particularly the unintentional misalignment of large AI models. Work in this area could explore methods to detect and mitigate sophisticated misbehaviour, such as alignment faking, reward hacking of human oversight, and encoded reasoning in chain-of-thought (CoT). Additionally, research could focus on enhancing robustness against adversarial attacks, jailbreaks, and backdoors. Further potential areas for innovation include advancing AI models transparency and interpretability. Safety research could also consider risks that may arise when embedding frontier models within agentic AI frameworks, significantly contributing to the trust and safe adoption of powerful AI solutions.

This topic contributes to the EU Frontier AI initiative. The project should establish strong links with the Resource for AI Science in Europe (RAISE), ensuring that its priorities inform the research topics addressed. Activities are expected to involve the European AI research community and attract and retain top AI talent working on frontier models and related areas.

All proposals are expected to incorporate mechanisms for assessing and demonstrating progress, including qualitative and quantitative KPIs, benchmarking, and progress monitoring. When possible, proposals should build on and reuse public results from relevant previous funded actions. Communicable results should be shared with the European R&D community through the AI-on-demand platform.

The project selected in this topic should link to the resources offered by the AI Factories and the Data Labs. Where relevant, it could also establish links with European companies developing frontier AI models.

All proposals are expected to allocate tasks for cohesion activities with the European Partnership on AI, data, and robotics (ADRA) and the CSA HORIZON-CL4-2025-03-HUMAN-18: GenAI4EU central Hub.

Apply AI

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-05-DIGITAL-EMERGING-02: Next-Generation AI Agents for Real-World Applications in the Apply AI sectors (RIA) (Partnership in AI, Data and Robotics)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 19.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 38.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 100 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 101

Technology Readiness Level

Activities are expected to start at TRL 2 and achieve TRL 5 by the end of the project – see General Annex B.

Expected Outcome: While today’s AI agents still have limited capabilities, advances in model architecture, memory, reasoning, and autonomous behaviour are paving the way to unlocking their potential across economic sectors. The Apply AI Strategy 102 acknowledges this trend and the need to advance research on next-generation AI agents. Project results are expected to contribute to some of the following expected outcomes:

1.Significant improvements in the autonomy, robustness and reliability of AI agents through advanced planning mechanisms, memory management, and reasoning capabilities.

2.Innovative multi-agent frameworks and protocols demonstrating effective decentralized coordination and collaboration among multiple AI agents beyond the capabilities of individual agents.

Scope: Next-generation AI agents are autonomous systems powered by large AI language models (e.g., large language models or large multimodal models), that can plan, utilize tools and perform actions autonomously to achieve specified goals based on high-level instructions. The large AI model acts as the agent's "brain," capable of interpreting instructions, generating plans, and using tools. This capability enables agents to autonomously plan and adapt behaviour in real-time to accomplish complex, multi-step tasks. AI Agents hold significant promise in numerous applications areas such as data analytics and coding.

Effective AI agents require careful design, incorporating structured planning and reasoning methods to manage complex tasks, and be equipped with appropriate validation and monitoring techniques. Multi-agent collaboration frameworks further enhance capabilities by enabling structured interactions among multiple agents.

Key aspects in designing effective AI agents include robust planning, reasoning, and search mechanisms that allow agents to approach complex tasks by breaking them down into structured subgoals. Effective memory and state management are necessary to maintaining coherent long-term interactions, achieved through a balanced integration of short-term and external long-term memory solutions. Moreover, integrating external tools and APIs is essential for overcoming limitations in large AI models, enhancing agent performance in tasks requiring accuracy and reliability.

Potential research areas include enhancing AI agent autonomy through advanced self-planning and self-optimization capabilities, enabling agents to improve their decision-making and strategic planning. Other research directions include innovation in memory-augmented AI agents to facilitate robust long-term reasoning and lifelong learning; developing advanced multi-agent frameworks specifically tailored for collaborative agents, including research on AI agent frameworks based on mixed AI architectures, and advancing multimodal reasoning capabilities to enable real-world applications.

All proposals are expected to incorporate mechanisms for assessing and demonstrating progress, including qualitative and quantitative KPIs, benchmarking, and progress monitoring. When possible, proposals should build on and reuse public results from relevant previous funded actions. Communicable results should be shared with the European R&D community through the AI-on-demand platform.

Projects selected in this topic should link to the resources offered by the AI Factories, including the Data Labs. The results may be validated in the Testing and Experiment Facilities and further deployed via the European Digital Innovation Hubs (EDIHs) and will contribute to the Apply AI strategy.

This topic implements the co-programmed European Partnership on AI, data, and robotics (ADRA), and all proposals are expected to allocate tasks for cohesion activities with ADRA and the CSA HORIZON-CL4-2025-03-HUMAN-18: GenAI4EU central Hub. Proposals should also build on or seek collaboration with relevant projects and develop synergies with other relevant International, European, national, or regional initiatives.

HORIZON-CL4-2027-04-DIGITAL-EMERGING-04: Apply AI: Challenge-Driven AI Innovation Booster in Apply AI prioritised sectors (RIA) (Partnership in AI, Data and Robotics)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 14.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 42.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 103 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 104

Technology Readiness Level

Activities are expected to start at TRL 2 and achieve TRL 5 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a portfolio coverage, grants will be awarded to applications not only in order of ranking, but also to at least one proposal focusing on each of the three sectors (one in healthcare, one in advanced manufacturing and one in-vehicle autonomous driving), subject to proposals passing all evaluation thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries must provide financial support to third parties. The support to third parties can only be provided in the form of grants.

FSTP grants may be provided to either a single SME or to a small team of legal entities. Where provided to a small team, the coordinator (lead applicant) must be an SME and other recipients of financial support must be either an SME, a research organisation, and/or public body secondary or higher education establishment.

FSTP amounts:

1.The maximum amount to be granted per FSTP grant (whether provided to one legal entity or a team of legal entities) is EUR 300,000 in stage 2 and EUR 2,250,000 in stage 3.

2.The amount of EUR 300,000 in stage 2 is justified as the challenge and corresponding tasks defined for this stage must be complex enough in order to take the best and most informed decision in the selection for the next stage based on a convincing technical prototype/proof of concept that reaches sufficient level of performance in terms of scale and maturity.

3.The amount of EUR 2,250,000 in stage 3 is justified by the ambition of reaching significant technology progress and innovation, defined in the expected outcome of the call, including the need for the selected projects to scale their solutions to the maturity expected.

The maximum amount to be granted to each third party is EUR 2,550,000.

In accordance with Annex 5 of the grant agreement “SPECIFIC RULES FOR CARRYING OUT THE ACTION (— ARTICLE 18) Implementation in case of restrictions due to strategic assets, interests, autonomy or security of the EU and its Member States”, by default beneficiaries must ensure that, inter alia, no recipient of FSTP is (i) established in a country which is not an eligible country (as identified in the specific conditions for eligibility) or (ii) controlled by such countries or entities from such countries (directly or indirectly as per the specific conditions for eligibility). In line with the possibility for the granting authority to agree otherwise, as concerns control of SMEs or private research organisations that participate as recipients of FSTP, beneficiaries must only ensure that such entities are not directly majority-owned (i.e., more than 50% of the capital) by entities established in non-eligible countries.

Expected Outcome: The Apply AI Strategy 105 proposes a comprehensive set of measures to notably harness the transformative potential of AI. It lays down targeted measures to boost AI use in key strategic sectors of the EU economy including healthcare, mobility and manufacturing for example. With challenges designed to spark breakthroughs in such strategic sectors, the current topic will directly support key activities of the Apply AI Strategy.

Project results are expected to contribute to all of the following expected outcomes:

1.Significant technological progress and innovation in Apply AI Strategy's prioritised sectors driven by challenge-oriented, AI-powered solutions.

2.Increase competitiveness and visibility of the relevant AI community within key application domains, and promote collaborative approaches for AI development in these domains, fostering the ecosystem.

3.Increase adoption of AI technologies across the following three key application domains: healthcare, advanced manufacturing (including AI-powered robotics) and in-vehicle autonomous driving.

Scope: The Challenge-Driven AI Innovation Booster aims to drive significant technological progress and innovation in Apply AI prioritised sectors through challenge-oriented, AI-powered solutions. This initiative seeks to boost Europe's developer community and the adoption of powerful, trustworthy AI solutions in three strategic domains such as:

1.In healthcare - advanced AI will accelerate diagnostics and treatment plans, enhance robotic surgery, or improve patient care through predictive analytics.

2.In advanced manufacturing - advanced AI will optimize production processes, improve quality control and product design, or enable predictive maintenance.

3.In autonomous driving - advanced AI will enhance vehicle safety, improve navigation systems, or optimize traffic management. Provided sufficient quality of the proposals received, at least one selected project will focus on in-vehicle autonomous driving applications, in line with the Automotive Action Plan, ensuring coordination with the announced Connected and Autonomous Vehicle Alliance.

Each proposal should focus exclusively on one of the three key sectors mentioned above.

It is expected to focus primarily on the definition and organization of a multi-stage competition in the chosen sector, as well as on the accompanying support to the SMEs/teams taking part in each of the challenges.

User-industry companies from the strategic sector targeted by the proposal should be core partners in each consortium. They should demonstrate a genuine interest in the project results and therefore support the challenge participants to reach the most powerful and exploitable results benefiting their industry. The expected results are pre-competitive, but the proposal must include a draft exploitation plan focused on how the solutions developed by the third parties will be taken up, with support from the user-industry partners for their future exploitation.

The consortium leading the project is responsible for the various stages of the challenges. This consortium should provide the necessary support resources during each stage of the competition (including technical assistance and business support to develop an exploitation strategy) and, most importantly, the consortium should ensure that the teams competing for and receiving financial support to third parties have access to relevant data to fine-tune models and build high-impact solutions meeting industry needs.

Proposals should be driven by impactful use-cases where advanced AI can make the difference: a number of industries from the targeted sector are expected to join forces to define challenging problems to solve with advanced AI solutions, which then drive the rest of the project. Based on such challenges, each project consortium should organize a multi-staged competition with an increasing level of complexity. In the different stages (see below), third parties, either single SMEs or small teams of organisations led by an SME, compete to address the challenges with advanced AI solutions.

For each proposal:

Stage 1 - Open call: The consortium launches an open call for proposals. A challenge, open to all, will allow the selection for Stage 2 of the 10 highest-ranked proposals according to a pre-defined selection process and criteria. Each solution is expected to be submitted either by a single SME, developer of advanced AI solutions, or a small team of organizations led by such SME.

Stage 2 - Competition among Stage 1 winners: The 10 teams or organisations selected from Stage 1 receive a EUR 300,000 FSTP grant each in accordance with their successfully selected proposal (which addresses the tasks and challenges defined for this stage by the consortium). At the end of Stage 2, the 4 highest-ranked solutions will be selected for the next stage according to a pre-defined selection process and criteria.

Stage 3 – Grand finale (Competition among Stage 2 winners): The 4 teams or organisations selected from Stage 2 receive EUR 2,250,000 FSTP grants each in accordance with their successfully selected proposals to address the tasks and challenges for this stage. In conjunction, they will prepare for the grand finale that will identify the best performing solution at the end of Stage 3 according to the evaluation methodology defined by the consortium.

The consortium should define measures to support the winners in maximizing the impact and uptake of their solutions. For instance, after the end of the FSTP grant, the best-performing team could be offered the opportunity to conclude partnerships or contracts with the user industries leading the consortium. Measures to support the broad uptake of their solutions in the whole sector should also be considered.

Such a multi-staged scheme is expected to be implemented in parallel by the projects funded under this action, each addressing a different sector.

Each proposal, involving several major industry players, should define a clear methodology to implement the various steps of the approach, define the specifications of the stages of the competitions, timelines, targets, KPIs, and propose a solid evaluation methodology including evaluation criteria. The main information should be in the proposal, in addition to all mandatory requirements as concerns financial support to third parties. The beneficiaries will also be in charge of implementing the evaluation methodology and providing the necessary infrastructure/technical support for the participants in the challenges. The consortium members are also responsible for ensuring high visibility of the competitions.

The projects selected from this call, each addressing one of the three targeted sectors, are expected to collaborate among themselves to make economies of scale in sharing best practices, defining processes for organizing the challenges, ensuring efficient monitoring, organizing dissemination and communication activities, etc. Such collaboration among the linked actions is expected to be formalized by a collaboration agreement after the grant agreement signature.

For each proposal, a total of EUR 3,000,000 is foreseen to be distributed among the winners of Stage 1, in the form of FSTP grants, to prepare for Stage 2. In addition, EUR 9,000,000 is foreseen to be distributed among the winners of Stage 2, in the form of FSTP grants, to prepare for Stage 3 of the challenge. The proposal is expected to make the case for such investment in defining the objectives and expected results. This amount will be distributed equally among the 4 winning teams of Stage 2, who are expected to develop further their solutions and compete for Stage 3.

Visibility would be important; therefore, dissemination and communication campaigns are key. The proposers are also encouraged to seek sponsorship, which would be key for the visibility and prestige of their challenge and to attract the best developers from the eligible countries to compete, particularly SMEs, alone or within a team competing for the challenges.

All proposals are expected to incorporate mechanisms for assessing and demonstrating progress, including qualitative and quantitative KPIs, benchmarking, and progress monitoring.

When possible, proposals should build on and reuse public results from relevant previous funded actions. Communicable results should be shared with the European R&D community through the AI-on-demand platform and, if necessary, other relevant digital resource platforms to bolster the European AI, Data, and Robotics ecosystem by disseminating results and best practices.

This topic implements the co-programmed European Partnership on AI, data, and robotics (ADRA), and all proposals are expected to allocate tasks for cohesion activities with ADRA and the CSA HORIZON-CL4-2025-03-HUMAN-18: GenAI4EU central Hub.

Proposals should also build on or seek collaboration with relevant projects and develop synergies with other relevant International, European, national, or regional initiatives. Projects selected in this topic will link to the resources offered by the AI Factories, including the Data Labs. The results may be validated in the Testing and Experiment Facilities and further deployed via the European Digital Innovation Hubs (EDIHs) and will contribute to the Apply AI strategy.

HORIZON-CL4-2026-04-DIGITAL-EMERGING-19: Challenge-Driven GenAI4EU Booster in Apply AI prioritised sectors (RIA) (AI/Data/Robotics Partnership)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 15.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 45.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 106 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 107

Technology Readiness Level

Activities are expected to start at TRL 3 and achieve at least TRL6 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering the different strategic sectors, grants will be awarded to applications not only in order of ranking but at least also to one proposal that is the highest ranked within (i) the aerospace sector, (ii) the pharma/drug development sector, and (iii) the telecommunication sector, provided that the applications attain all thresholds.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries must provide financial support to third parties. The support to third parties can only be provided in the form of grants. FSTP grants may be provided to either a single SME or to a small team of legal entities. Where provided to a small team, the coordinator (lead applicant) must be an SME and other recipients of financial support must be either an SME, a research organisation, and/or public body secondary or higher education establishment.

FSTP amounts:

1.The maximum amount to be granted per FSTP grant (whether provided to one legal entity or a team of legal entities) is EUR 250,000 in stage 2 and EUR 2,000,000 in stage 3.

2.The amount of EUR 250,000 in stage 2 is justified as the challenge and corresponding tasks defined for this stage must be complex enough in order to take the best and most informed decision in the selection for the next stage based on a convincing technical prototype/proof of concept that reaches sufficient level of performance in terms of scale and maturity.

3.The amount of EUR 2,000,000 in stage 3 is justified by the ambition of reaching significant technology progress and innovation, defined in the expected outcome of the call, including the need for the selected projects to scale their solutions to the maturity expected.

The maximum amount to be granted to each third party is EUR 2,250,000

In accordance with Annex 5 of the grant agreement “SPECIFIC RULES FOR CARRYING OUT THE ACTION (— ARTICLE 18) Implementation in case of restrictions due to strategic assets, interests, autonomy or security of the EU and its Member States”, by default beneficiaries must ensure that, inter alia, no recipient of FSTP is (i) established in a country which is not an eligible country (as identified in the specific conditions for eligibility) or (ii) controlled by such countries or entities from such countries (directly or indirectly as per the specific conditions for eligibility). In line with the possibility for the granting authority to agree otherwise, as concerns control of SMEs or private research organisations that participate as recipients of FSTP, beneficiaries must only ensure that such entities are not directly majority-owned (i.e., more than 50% of the capital) by entities established in non-eligible countries.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes:

1.Significant technology progress and innovation through challenge-driven approach in the fields of aerospace, pharma/drug development or telecommunication networks.

2.Increased competitivity and visibility of the Generative AI community in Europe, in demonstrating their capability to achieve challenging tasks within the aerospace, pharma/drug development or telecommunication sectors.

3.Increased adoption of Generative AI in aerospace, pharma/drug development or telecommunication networks through tangible progress and achievement demonstrated via the challenge-driven process.

Scope: Generative AI (GenAI) promises to transform most industry sectors. This challenge-driven initiative aims to boost both Europe’s developer community and the adoption of powerful trustworthy generative AI solutions in the strategic sectors of aerospace, pharma/drugs and telecommunication networks, key for their competitiveness. In pharmaceuticals, it can, for instance, accelerates drug design by rapidly creating target-specific molecules, reducing development time from years to seconds, and potentially preventing prolonged health crises like COVID-19. In aerospace, generative AI can for instance optimize aircraft design, streamline manufacturing processes, predict maintenance needs through sensor data analysis, route optimisation, and enhance pilot training with diverse, realistic simulations. By embracing generative AI, telecom companies can position themselves at the forefront of a new era of intelligent and automated telecommunications. Specific use-cases include for instance network management, network optimization, network slicing, network healing, predictive maintenance, network mapping and optimization.

Each proposal should focus exclusively on one of the three key sectors mentioned above: aerospace, pharma/drug development, or telecommunications and clearly specify which sector it addresses. Each proposal is expected to focus primarily on the definition, the organization of a multi-stage competition in the chosen sector, as well as the accompanying support to the companies/teams taking part in the challenges, and related activities to maximise the impact of the action.

User industry companies from the strategic sector targeted by the proposal should be core partners in the consortium. They should demonstrate a genuine interest in the projects results and therefore support the challenge participants - in order to reach the most powerful and exploitable results benefitting their industry. The expected results are pre-competitive but the proposal must include a draft exploitation plan outlining commitments on future exploitation. The consortium is responsible for the various stages of the challenges and should provide the necessary support resources during each stage of the competition, including technical assistance and business support to develop an exploitation strategy, but most importantly, provide to the competing FSTP recipients the data necessary to fine-tune models and build powerful solutions meeting industry needs.

Proposals should be driven by impactful use-cases where generative AI can make the difference: a number of industries from the targeted sector are expected to join forces to define challenging problems to solve with GenAI solutions, which then drive the rest of the project. Based on such challenges, the consortium organises a multi-staged competition with an increasing level of complexity. In the different stages (see below), third parties, either single SMEs or small team of organisations led by an SME, compete to address the challenges with GenAI solutions.

For each proposal:

1.Stage 1 - Open call: The consortium launches an open call for proposals. A challenge, open to all, will allow to select for Stage 2 the 20 highest-ranked proposals, according to a pre-defined selection process and criteria. Each solution competing for the challenge can be submitted either by a single SME, developer of GenAI solutions, or a small team of organisations led by such SME

2.Stage 2 - Competition among Stage 1 winners: The 20 teams or organisations selected from Stage 1 receive EUR 250 000 FSTP grant each in accordance with their successfully selected proposal (which addresses the tasks and challenges defined for this stage by the consortium). At the end of Stage 2, the 4 highest ranked solutions will be selected for the next stage according to a pre-defined selection process and criteria.

3.Stage 3– Grand finale (Competition among Stage 2 winners): The 4 teams or organisations selected from Stage 2 receive EUR 2,000,000 FSTP grants each in accordance with their successfully selected proposals to address the tasks and challenges for this stage. In conjunction, they will prepare for the grand finale that will identify the best performing solution at the end of Stage 3 according to the evaluation methodology defined by the consortium.

The consortium should define measures to support the winners in maximizing the impact and uptake of their solutions. For instance, after the end of the FSTP grant, the best performing team could be offered the opportunity to conclude partnerships or contracts with the user industries leading the consortium. Measures to support the broad uptake of their solutions in the whole sector should also be considered.

Such multi-staged scheme is expected to be implemented in parallel by the projects funded under this action, each addressing a different sector.

Each proposal, involving several major industry players, should define a clear methodology to implement the various steps of the approach, define the specifications of the stages of the competitions, timelines, targets, KPIs, a solid evaluation methodology including evaluation criteria. The main information should be in the proposal, in addition to all mandatory requirements as concerns financial support to third parties. The beneficiaries will also be in charge of implementing the evaluation methodology, and providing the necessary infrastructure/technical support for the participants to the challenges. The consortium members are also responsible for ensuring high visibility of the competitions.

The projects selected from this call, each addressing one of the three targeted sectors, are expected to collaborate among themselves, in order to make economies of scale in sharing best practices, defining processes for organising the challenges, ensuring efficient monitoring, organising dissemination and communication activities, etc. Such collaboration among the linked actions is expected to be formalised by a collaboration agreement, after the grant agreement signature.

For each proposal, an amount of EUR 5,000,000 is foreseen to be distributed among the winners of Stage 1, in form of FSTP grants, in order to prepare for Stage 2. In addition, a budget of EUR 8,000,000 is foreseen to be distributed among the winners of Stage 2, in the form of FSTP grants, to prepare for Stage 3 of the challenge.

The proposal is expected to make the case for such investment in defining the objectives with sufficient level of information. This amount will be distributed equally among the 4 winning teams of Stage 2, who are expected to develop further their solutions and compete for Stage 3.

Visibility would be important; therefore dissemination and communication campaigns are key. The proposers are also encouraged to seek sponsorship, which would be key for the visibility and prestige of their challenge, and to attract the best developers from the eligible countries to compete, particularly SMEs, alone or within a team competing for the challenges.

All proposals are expected to incorporate mechanisms for assessing and demonstrating progress, including qualitative and quantitative KPIs, benchmarking, and progress monitoring.

When possible, proposals should build on and reuse public results from relevant previous funded actions. Communicable results should be shared with the European R&D community through the AI-on-demand platform, and if necessary, other relevant digital resource platforms to bolster the European AI, Data, and Robotics ecosystem by disseminating results and best practices.

This topic implements the co-programmed European Partnership on AI, data and robotics (ADRA), and all proposals are expected to allocate tasks for cohesion activities with ADRA and the CSA HORIZON-CL4-2025-03-HUMAN-18: GenAI4EU central Hub.

Proposals should also build on or seek collaboration with relevant projects 108 and develop synergies with other relevant International, European, national or regional initiatives. Projects selected in this topic will link to the resources offered by the AI Factories, including the Data Labs. The results may be validated in the Testing and Experiment Facilities and further deployed via the European Digital Innovation Hubs (EDIHs) and will contribute to the Apply AI strategy 109 .

Robotics

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-05-DIGITAL-EMERGING-03: Apply AI: Next-Generation Agile and Intelligent Robotics Platforms for Industrial and Service Applications (Partnership in AI, Data and Robotics) (RIA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 12.00 and 13.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 25.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 110 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 111

Technology Readiness Level

Activities are expected to start at TRL 2 and achieve TRL 5 by the end of the project – see General Annex B.

Expected Outcome: The Apply AI Strategy foresees acceleration pipelines to speed up the adoption of AI-powered robotics and ensure continuity from research and innovation to deployment. By developing next-generation platforms as common building blocks, this topic will support these pipelines across multiple use cases.

Project results are expected to contribute to all of the following expected outcomes:

1.Novel robot design technique, materials and control techniques for flexible and meticulous manipulation of robots in unstructured environment, with high autonomy and in collaboration with humans.

2.New generation of flexible and safe robot systems validated in key application sectors defined in the Apply AI strategy 112 , developed with a human-centric approach.

Scope: Dynamic real-world environments require a new generation of agile, cost-effective, and intelligent, and modular robot platforms able to interact in safe and effective manner with humans across diverse industrial and service applications. These systems should be easily reconfigurable and adaptable, enabling deployment in real-time, high-performance operational contexts with minimal integration effort.

To ensure relevance and uptake, solutions must address industrial demands for high speed, precision, and reliability, enabling deployment in real-time, high-performance operational contexts.

Emphasis should be placed on the development of robotic systems that can be seamlessly integrated into existing industrial and service workflows, enhancing productivity and operational flexibility.

In order to improve their performances, these platforms should exploit latest development in terms of new design methods, including non-rigid structures and advanced materials (e.g. composite materials), both for the main body and for manipulators and end effectors, alongside innovative actuation and sensing approaches that go beyond traditional fixed rotational or linear links.

Proposals should target robotic systems addressing high impact needs in strategic industrial and service sectors. These systems should focus on enhanced mobility, autonomy, and simplified control architectures to support safe, efficient, and flexible operation. Integration of advanced sensors (e.g. touch, proximity, vision) is essential to enable reliable human-robot interaction, especially in rare or unpredictable safety-critical scenarios, addressing current limitations of AI in such contexts.

They should also include the design of secure and efficient communication protocols to ensure interoperability between robotic systems and digital frameworks or multi-agent environments.

Collaboration with end-users and industry partners is encouraged to validate the practical applicability and impact of the proposed robotic solutions.

To ensure practical uptake, projects are expected to demonstrate clear pathways to scalability and commercial deployment, engage with industry partners and end-users for validation, adopt a safety-product approach

Coordination with HORIZON-CL4-2025-04-DIGITAL-EMERGING-05, focused on soft robotics, is encouraged to maximise impact and ensure complementarity in advancing physical capabilities of next-generation robotic systems.

This topic implements the co-programmed European Partnership on AI, data, and robotics (ADRA), and all proposals are expected to allocate tasks for cohesion activities with ADRA.

HORIZON-CL4-2027-04-DIGITAL-EMERGING-05: Apply AI: AI-Driven Robotics for Industry: Enabling System Integration and Adoption (IA) (Partnership in AI, Data and Robotics)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 18.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 18.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 113 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 114

Technology Readiness Level

Activities are expected to start at TRL 4 and achieve TRL 7 by the end of the project – see General Annex B.

Expected Outcome: The Apply AI Strategy emphasises acceleration pipelines to ensure a smooth transition from research to deployment of AI-powered robotics. Projects under this topic will deliver common frameworks and reusable building blocks that can serve multiple sectors and use cases, reinforcing Europe’s ability to bring AI-driven robotics to scale.

Project results are expected to contribute to all of the following expected outcomes:

1.Wider and faster deployment of robotics, bridging the gap between technology providers and end-users.

2.Development and implementation of modular and interoperable integration frameworks and solutions, including standardized protocols for data, training and safety testing, evaluation and validation of robotic solutions in key use cases

3.Improved competitiveness of European industries, notably SMEs via the development of advanced robotics systems, intelligent planning and control systems, user feedback rendering techniques and cutting-edge AI innovations

Scope: The project will address the current European gap in system integration capabilities for robotics solutions addressing the various needs of industries. The project will aim at disseminating a deep understanding of state-of-the-art robotics components, including both hardware and software, and expertise in addressing interoperability issues for the upskilling of system integrators.

To maximise the impact and adaptability of deployed systems, the approach should consider the most appropriate tools to speed up integration processes and suitable AI design, training and inference methodologies, ensuring scalability, transferability, transparency, robustness, flexibility, and real-world applicability in diverse industrial environments, and should remain adaptable to the latest technological developments.

Integration frameworks will promote the use of energy-efficient AI models and hardware ('Green AI'), alongside carbon-aware deployment and operational strategies for robotic system. Where relevant, projects should contribute to open and widely recognised standards to foster interoperability and uptake across the robotics ecosystem. To enhance safety and performance, projects may include high-fidelity simulation environments or digital twins as testbeds for training, validation and verification, with measures to ensure smooth transfer from simulation to real-world deployment.

By bridging the gap between technology providers and end-users, these integrators will enable the creation of seamless, reliable and scalable robotics systems that can be easily adopted by industries, especially SMEs, thereby supporting more flexible and efficient production processes.

The project is expected to deliver:

1.A deployable, modular integration framework, validated through at least three real-world industrial pilots covering different reference scenarios to demonstrate that the approach can be adapted to varied industrial needs and company sizes, including both SMEs and larger manufacturers. This framework should provide, for example, a common software layer, standard interfaces to connect to existing workflow and legacy system, possibly also to connect various robot components, coordinate multiple robots and link them with additional AI tools and IoT environments, as well as tested configuration templates and clear guidelines to ensure safe and efficient use.

2.An Integration Kit, building on this framework, which offers ready-to-use modules, example configurations and practical tools that help system integrators and companies to set up, test and run AI-enabled robotics solutions more quickly and with reduced technical effort.

3.Where relevant, high-fidelity digital twin testbeds should be linked to each pilot, allowing safe and realistic testing and training before deployment, and supporting a smooth transition from virtual models to actual production lines.

4.Reusable, datasets (compliant with relevant regulation and IP protection) and practical benchmark tasks, made available to the wider robotics and AI community, to support further development and comparison of new solutions while respecting European data protection rules.

5.A clear Step-by-Step Adoption Guide aimed at SMEs and other end-users, providing easy-to-follow instructions, practical checklists and examples to help companies plan, budget and implement AI-driven robotics in a safe and cost-effective way, even if they have limited in-house expertise, and including guidance to navigate regulatory compliance and certification.

6.Concrete contributions to relevant open standards and clear guidance on certification pathways, to help ensure compliance with European regulations and build trust in the safe use of AI in robotics. Projects are expected to make full use of existing robotics resources and assets made available through the AI-on-Demand Platform, such as the EuroCORE repository and other relevant shared tools, to maximise synergies, avoid duplication of efforts and ensure broad dissemination and reuse of results within the European AI and robotics community.

This topic implements the co-programmed European Partnership on AI, data, and robotics (ADRA), and all proposals are expected to allocate tasks for cohesion activities with ADRA.

HORIZON-CL4-2026-04-DIGITAL-EMERGING-08: Apply AI: Robotics for Manufacturing: Advancing Core Skills through Technical Challenges (RIA) (Partnership in AI, Data and Robotics)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 18.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 18.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 115 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 116

Technology Readiness Level

Activities are expected to start at TRL 2 and achieve TRL 5 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Beneficiaries must provide financial support to third parties. The support to third parties can only be provided in the form of grants.

FSTP grants may be provided to either a single SME, research organisation or public body secondary or higher education establishment or a small team composed of such organizations.

FSTP amounts:

1.The maximum amount to be granted per FSTP grant (whether provided to one legal entity or a team of legal entities) is EUR 200,000 in stage 2 and EUR 1,000,000 in stage 3.

2.The amount of EUR 200,000 in stage 2 is justified as the challenge and corresponding tasks defined for this stage must be complex enough in order to take the best and most informed decision in the selection for the next stage based on a convincing technical prototype/proof of concept that reaches sufficient level of performance in terms of scale and maturity.

3.The amount of EUR 1,000,000 in stage 3 is justified by the ambition of reaching significant technology progress and innovation, defined in the expected outcome of the call, including the need for the selected projects to scale their solutions to the maturity expected.

The maximum amount to be granted to each third party is EUR 1,200,000.

In accordance with Annex 5 of the grant agreement “SPECIFIC RULES FOR CARRYING OUT THE ACTION (— ARTICLE 18) Implementation in case of restrictions due to strategic assets, interests, autonomy or security of the EU and its Member States”, by default beneficiaries must ensure that, inter alia, no recipient of FSTP is (i) established in a country which is not an eligible country (as identified in the specific conditions for eligibility) or (ii) controlled by such countries or entities from such countries (directly or indirectly as per the specific conditions for eligibility). In line with the possibility for the granting authority to agree otherwise, as concerns control of SMEs or private research organisations that participate as recipients of FSTP, beneficiaries must only ensure that such entities are not directly majority-owned (i.e., more than 50% of the capital) by entities established in non-eligible countries.

Expected Outcome: The Apply AI Strategy highlights the need to accelerate the uptake of AI-powered robotics through sectoral pipelines that connect research and deployment. By developing advanced robotics skills based on foundation models and creating adaptable frameworks that can be transferred across different industrial contexts, including automotive, this topic will provide common tools and building blocks to strengthen those pipelines and ensure broad industrial relevance.

Project results are expected to contribute to all of the following expected outcomes:

1.Development of advanced robotics skills (e.g. high precision autonomous pick and place manipulation, autonomous navigation in unstructured environments) using robotics foundation models, tailored for manufacturing. Creation of a comprehensive framework for general purpose and flexible robotics skills development with industry-relevant challenges, evaluation metrics and success criteria.

2.Facilitation of widespread deployment of robotics in manufacturing especially SMEs, through modular, adaptable, and reconfigurable solutions built on robotics foundation models, to meet evolving production needs

Scope: The proposed project aims to significantly enhance robotics capabilities in manufacturing by developing advanced robotics skills (for example, task and environment aware autonomous pick and place with high precision and speed, human-robot collaboration, etc).

By leveraging the use of next-generation AI, including generative AI, to enable robots to better adapt to real-world environments and interact with human operators, and focusing on reconfigurability, the project will develop industry-agnostic solutions that can be easily adapted to different manufacturing environments.

The project will create a comprehensive framework for robotics skills development in manufacturing, including the initial definition of three technical challenges that must be clearly described at proposal stage, with evidence of their industrial relevance and potential impact. The detailed specification and design of these challenges may be further refined during the first phase of the project in collaboration with industry partners.

The project will organize a multi-stage competition for each of the three identified technical challenges. Each stage of the competition is expected to present an increased level of complexity compared to the previous one. The approach for designing the competitive process, including the use of FSTP, should aim at maximising the impact.

One of the key use cases for this project will be the automotive industry, which should be explicitly included in proposals either as a primary focus or as a dedicated use case, demonstrating how advanced robotics can enhance production efficiency and adaptability in this sector. Other use cases alongside the automotive one are allowed and encouraged, to demonstrate the industry-agnostic nature and the transferability of the developed solutions to different industrial contexts.

User-industry companies from the manufacturing sector (including automotive) should be core partners in the consortium. They should demonstrate a genuine interest in the project results and actively support the FSTP recipients in achieving powerful and exploitable results that benefit their industry.

Organization of the Challenge:

Stage 1 – Open call: The consortium launches an open call for proposals. A challenge, open to all, will allow the selection of the 10 highest-ranked proposals for each of the three technical robotics skills, according to a pre-defined selection process and criteria. Each solution competing for the challenge can be submitted either by a single SME, research organisation or public body secondary or higher education establishment, developer of robotics solutions, or a small team of organizations.

Stage 2 – Competition among Stage 1 winners: The 10 teams or organisations selected from Stage 1 will receive a EUR 200,000 FSTP grant each in accordance with their successfully selected proposal (which addresses the tasks and challenges defined for this stage by the consortium). At the end of Stage 2, the 3 highest-ranked competing solutions will be selected for the next stage according to a pre-defined selection process and criteria.

Stage 3 – Grand Finale (competition among Stage 2 winners): The 3 best teams or organisations selected from Stage 2 will receive a EUR 1,000,000 FSTP grant each in accordance with their successfully selected proposals to address the tasks and challenges defined for this stage. In conjunction, they will prepare for the grand finale that will identify the best performing solution at the end of Stage 3 according to the evaluation methodology defined by the consortium.

The consortium should define measures to support the team winning the grand finale in maximising the impact and uptake of its solutions.

Proposals must include a draft exploitation plan outlining how the solutions developed by the FSTP recipients will be taken up, with concrete support from the user-industry partners to ensure industrial relevance and future exploitation.

This scheme is repeated for each of the three technical challenges.

The consortium will ensure high visibility of the competitions, including possible sponsorships, and will seek to attract the best developers from the EU and associated countries to compete, particularly SMEs, alone or within a team competing for the challenges.

All proposals are expected to incorporate mechanisms for assessing and demonstrating progress, including qualitative and quantitative KPIs, benchmarking, and progress monitoring. This should include the methodology to accompany the challenge participants to the various stages during the project and the assessment methodology during the various selection stages.

When possible, proposals should build on and reuse public results from relevant previous funded actions. Communicable results should be shared with the European R&D community through the AI-on-demand platform and, if necessary, other relevant digital resource platforms to bolster the European AI, Data, and Robotics ecosystem by disseminating results and best practices.

This topic implements the co-programmed European Partnership on AI, data, and robotics (ADRA), and all proposals are expected to allocate tasks for cohesion activities with ADRA

Proposals should also build on or seek collaboration with relevant projects and develop synergies with other relevant International, European, national, or regional initiatives.

AI4GOOD

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-04-DIGITAL-EMERGING-09: Advanced Local Digital Twins using AI for Early Warning and Preparedness (IA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 6.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 6.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Due to the scope of this topic, international organisations with headquarters in a Member State or Horizon Europe Associated Country are exceptionally eligible for funding.

The Joint Research Centre (JRC) may participate as member of the consortium selected for funding as a beneficiary with zero funding, or as an associated partner. The JRC will not participate in the preparation and submission of the proposal - see General Annex B.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Subject to restrictions for the protection of European communication networks.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 117 .

Expected Outcome: Open AI models that can help predict, respond to, and mitigate impacts before a disaster occurs, enabling proactive decision-making and effective disaster management effectively.

Protection of citizens from natural hazards through proactive measures, preparedness strategies, and urban resilience, planning

Project results are expected to contribute to one of the following outcomes:

1.Enhanced protection of citizens from the natural hazard of flooding by facilitating proactive decision-making and effective disaster management through open AI-driven models for urban resilience strategies and planning that can help predict, respond to, and mitigate impacts before a disaster occurs.

2.Improved modelling and prediction of urban and riverine flooding by expanding the capabilities of Local Digital Twins with sophisticated AI algorithms and relevant data detailing hydrological and hydraulic processes.

3.Strengthened integration of diverse and essential datasets including detailed terrain, land cover, urban features, soil data, and real-time meteorological information (rainfall and temperature, river geometry, and flow) sourced from national hydrometric networks, urban drainage infrastructure, and flood protection assets. This integration aims to enhance flood analysis, simulation, and preparedness particularly in response to climate change and flood scenarios like heavy rainfall impacting nearby river basins.

The projects will leverage high-resolution climatic and meteorological models to assess extreme weather, while also drawing on relevant initiatives such as the Global Flood Awareness System and Destination Earth.

Scope: In line with the Apply AI Strategy, proposals should develop and implement projects that advance innovative AI algorithms and models from concept to large-scale testing and validation. These solutions will be applied to the creation of Local Digital Twins for flood preparedness, enabling the simulation of flood scenarios, identification of areas at risk, and estimation of potential damage.

1.Proposals should focus on the development of innovative AI algorithms that move beyond rigid functions, employing instead a dynamic set of descriptive building features derived from digital models (e.g., geometrical parameters, urban morphology, socio-economic indicators). These algorithms should be integrated with advanced, high-resolution hazard models — including hydrological and hydraulic models — tailored to the specific characteristics of the local area.

2.The Local Digital Twins will enable:

1.Flood damage models capable of calculating building-scale impacts, forming the basis for damage hotspot maps.

2.Interactive user interfaces that allow components to be exchanged, modified, and reconfigured to estimate flood damage under various urban planning and risk management scenarios — for example, assessing the feasibility of proposed or existing constructions in flood-prone zones and recommending targeted mitigation strategies.

The scope of this topic includes a strong research and innovation component aimed at the prototyping, testing, and large-scale validation of tailored AI algorithms designed to model multiple disaster types, with a focus on operational deployment in real-world contexts. .It is recommended to prioritise the use of frugal (and local) AI as much as possible. This approach will both reduce greenhouse emissions -an indirect driver of climate-related disasters- and ensure that the tools remain functional in environments with limited connectivity.

Proposals should take into account the expertise of the European Commission's Joint Research Centre (JRC) 118 , particularly its experience in developing global systems for disaster and risk management and analyse the potential uptake of the project outcomes by the Copernicus Emergency Management Service. In addition, proposals should align with for the 2025 Mission call on Local Digital Twin for urban planning, ensuring interoperability and complementarity with related European initiatives.

The project results should be modular for reuse in locations outside Europe considering constraints on deployment of AI solutions in low- and middle-income countries. Therefore, the project results shall be open source as much as possible and transferable through open platforms.

1.Focus will be on open-source solutions (both software and hardware) and their integration into existing platforms (e.g. EDIC 119 ) to ensure replicability of the results and portability in different areas.

2.The proposal should support open-source software and open hardware design. Applicants are encouraged to support, open access to data, access to testing and operational infrastructures as well as an IPR regime ensuring lasting impact and reusability of results.  

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

HORIZON-CL4-2027-04-DIGITAL-EMERGING-06: International cooperation in AI (IA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.00 million.

Type of Action

Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Technology Readiness Level

Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 120 .

Expected Outcome: Project results are expected to contribute to one of the following outcomes:

1.Faster uptake of tailored and enhanced AI solutions at innovation hubs in low- and middle-income countries by training and optimising them with local data and applied research.

2.Easier large-scale deployment of local AI solutions in low and middle-income countries by increasing the efficiency of system demonstration in relevant, operational environments.

3.Strengthened local innovation ecosystems that foster sustainable socio-economic impact by addressing key societal challenges in areas such as education, healthcare, agriculture, and environmental sustainability.

Scope: System prototype, testing, validation, and demonstration in operational environment aligned to EU initiatives, such as the International Digital Strategy for the EU 121 and the AI Continent Action Plan 122 , to strengthen local AI ecosystems in African countries fostering responsible AI development, north-south digital cooperation on AI, and sustainable AI innovation.

The main goal is to support the digital transition and foster inclusive economic and social transformation of partners globally by adapting and applying innovative solutions, research areas and capabilities developed in Europe to low- and middle-income countries.

This Innovation Action will focus on accelerating the uptake of and access to AI solutions by local innovation hubs in these countries, better enabling their practical implementation and future market deployment in operational environments. Proposals should consider synergies and complementarity of ongoing research and innovation activities in the policy areas of international partnerships, digital and infrastructure like the Digital for Development Hub 123 and AI for Public Good 124 , and may follow an approach like Living Labs. Proposals should also support the European Union’s Global Gateway strategy to boost smart, clean, and secure connections in digital, energy and transport sectors, and to strengthen health, education and research systems across the world. Proposals should enable AI technologies that are locally relevant and sustainable, empower local communities and platforms, and reflect the EU’s emphasis on sustainable and resilient global partnerships.

The proposals must support digital partnerships and international digital cooperation to promote an approach to AI that enhances human well-being and societal progress through:

1.Support for gathering of and access to local data in line with EU’s data strategy for the training and optimisation of existing AI algorithms developed in initiatives like AI for Public Good and GenAI for Africa.

2.Establishment and support of Living Labs within local innovation hubs in low-income countries, fostering co-creation spaces where community members, researchers, entrepreneurs, and policymakers can collaboratively tailor, enhance, test, and iterate AI-driven solutions. These Living Labs will serve as platforms for experiential learning, inclusive participation, and sustainable technology adoption.

3.Tailored and contextualized AI-based solutions developed through a bottom-up approach, driven by the specific needs of low-income communities. These solutions will be trained and adapted using local data sources, enabling meaningful knowledge transfer and empowering local stakeholders with relevant and actionable technologies.

4.Contribution, where possible, to solving global sustainable development challenges, especially climate and agriculture, biodiversity, health and humanitarian needs, education.

5.Fostering an enabling innovation environment with reinforced talent pipelines and technological transfer of AI algorithms and solutions to local innovation hub.

6.Full testing and validation of the solutions in real-life with scenarios and initial support to large-scale deployment in low and middle-income countries.

Capitalise from existing EU initiatives like the call GenAI for Africa from HE WP25, the Global Gateway, and Smart Africa to up-scale the deployment of solutions in low-income countries.

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

Quantum

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-04-DIGITAL-EMERGING-11: Grand Challenge on Quantum Sensors for Inertial Navigation

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 0.50 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 2.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 125 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 126

The following additional eligibility criteria apply: Proposals must be submitted by a single legal entity (mono-beneficiary CSA) wich is an SME.

Award criteria

The criteria are described in General Annex D. The following exceptions apply:

The following additions to the general award criteria aspects apply:

1.Excellence: credibility of the technical approach for road-mapping and benchmarking; adequacy of performance metrics and methodology (e.g. drift rate, SWaP-C, environmental resilience) and early end-user engagement to define requirements.

2.Impact: enhancing the EU stance around quantum inertial navigation from different angles 127 ; expected contribution to EU technological sovereignty (including mitigation of non-EU supply-chain dependencies) and to societal, industrial and economic benefits; credibility of the path to commercialisation and investor-readiness.

3.Quality and efficiency of the implementation: credibility of the work plan, resources and risk management for a mono-beneficiary CSA; capacity to deliver the specified outputs (technical & financial roadmap, validation/benchmarking reports, viability assessment); appropriateness of the team and access to facilities for validation/benchmarking of existing prototypes.

Expected Outcome: Expected Outcome: This topic is the first phase of a two-phase competitive structure supported by Horizon Europe, implemented via a Coordination and Support Action (CSA) in close collaboration with the European Investment Bank (EIB).

1.Phase 1 (this topic): A CSA focused on readiness-analysis in terms of exploitation and investments, benchmarking the commercial viability of quantum enabled navigation systems. The aim is to deliver concrete outputs that improve the conditions for use of the supported projects through credible technical, industrialisation and financial roadmaps, validated against investor requirements (e.g. EIB, InvestEU). Activities also include analyses of investor-readiness and supply-chain sovereignty.

2.Phase 2: For further information, see the indirectly managed action “HORIZON-CL4 Quantum Top-Up to InvestEU: Grand Challenge Phase 2” in the Cluster 4 part of the Horizon Europe 2026/2027 Work Programme. This CSA is designed to allow the best possible application in Phase 2 and the current CSA results may therefore inform applications by beneficiaries to investment support managed by the EIB under InvestEU (separate procedures).

Under Phase 1 projects are expected to establish a comprehensive technical and financial roadmap that demonstrates the potential of the proposed Q-INS solutions, and at least deliver evidence-based design and benchmarking packages for reduced-scale systems ( such as documentation, test/benchmark reports and evidence of pre-existing or externally financed prototypes) in one of the following two categories:

1.Category 1 (cold-atoms Q-INS): Q-INS based on cold-atom interferometry (or other technology of at least equivalent performance) featuring long-term navigation accuracy (<10 m/hour) due to reduced drift with respect to commercial Inertial Measurement Units (IMUs). End-user requirements together with documented benchmark evidence from existing or externally financed prototypes will be collected for demonstrations in maritime or aviation applications.

2.Category 2 (Chip-scale Q-INS): Low C-SWAP Q-INS measuring acceleration, rotation rate, and/or magnetic field, aimed at the implementation of chip-scale sensors based on defect centers and vacancies in crystals or on warm atomic vapours (including nuclear magnetic resonance), for applications e.g. in small satellites, UAVs, and autonomous transport.

Proposals should target systems that are already sufficiently mature to enable credible benchmarking and industrial road-mapping. Specific expected outcomes include:

1.A detailed technical roadmap, including system architecture, integration strategy, performance milestones, risk assessments and industrialisation plan for scalable production

2.The industrialisation plan should be validated in conjunction with the EIB requirements, including commercialization timelines, and should include at least the following:

1.Detailed Q-INS architecture based on quantum sensing techniques hybridised with classical IMUs,

2.Compliance assessment for SWaP-C requirements, environmental resilience, and real-world integration,

3.An assessment of dependencies on non-EU suppliers of critical components and proposal of effective mitigation measures in view of a sovereign supply chain,

4.Potential list of end-users to capture system requirements and use-case constraints

3.A comprehensive financial roadmap and viability assessment covering business models, market analyses, commercialization pathways, revenue projections and investment criteria

4.Documented lab-validation/benchmarking of an existing or externally financed prototype (no EU funding of R&I or prototype development in this CSA), with preliminary benchmark results.

5.An application strategy identifying target sectors (maritime, aviation, space, autonomous systems) and quantifiable advantages over classical IMUs.

Scope: The Grand Challenge on Quantum Sensors for Inertial Navigation aims to advance the development of quantum-enabled navigation systems for use in GNSS-denied or contested environments. Q-INS combines quantum sensors with classical inertial measurement subsystems to deliver reliable, resilient, and sovereign positioning capabilities. The topic supports the EU’s ambition to strengthen technological sovereignty in strategic navigation infrastructures, aligned with the objectives of the STEP and the Digital Decade.

Under this topic (Phase 1), projects are expected to deliver a comprehensive technical, industrialisation, and financial roadmap, including criteria for investment readiness, bankability, risk assessment, and scalability, thereby laying the groundwork for future investments via EU financial instruments under InvestEU, which benefits from a dedicated top-up from Horizon Europe for this purpose 128 .

Under Phase 1, Expressions of Interest from potential end-user partners are strongly encouraged. Tailored advisory services from EIB Advisory may support financial structuring to prepare for Phase 2.

Projects funded under this action are expected to span approximately six months, with an EU contribution up to EUR 0.5 million.

HORIZON-CL4-2026-04-DIGITAL-EMERGING-12: Standards for Quantum Technologies – Coordination and Support Action (CSA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 1.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

The conditions are described in General Annex B. The following exceptions apply: In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway, associated countries and OECD countries.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or a non-eligible country entity, shall not participate in the action.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 129 .

Expected Outcome: This action will support and accelerate the development and adoption of European and international standards for quantum technologies, enhancing interoperability quality/reliability assurance, and trust in quantum systems. It will strengthen Europe's leadership in the global quantum standardisation landscape and ensure that European industrial and research priorities are well represented and integrated into emerging standards.

Expected outcomes include:

1.Delivery of concrete, EU-relevant pre-normative standards and technical specifications across quantum computing, communication, and sensing.

2.Substantial contribution of European stakeholders, notably SMEs and start-ups in international standardisation bodies (e.g., ISO/IEC, ITU-T, ETSI), with alignment to EU industrial strategies.

3.Promotion of cross-sectoral interoperability through standardised interfaces, control protocols, reliability in operating conditions and benchmarking methodologies, reducing market fragmentation and technical barriers.

4.Creation of practical support tools such as user guidelines, training modules, and best practices to accelerate the uptake and implementation of quantum standards.

Scope: The CSA will coordinate and support standardisation activities for quantum technologies in areas such as quantum computing, communication, sensing, and control. Proposals should include:

1.Build on the roadmaps of European standardisation organisations to (i) standardise results from quantum projects funded under Horizon Europe, the Digital Europe Programme, and EuroHPC JU in line with stakeholder priorities, and (ii) foster an active industrial standardisation community to promote engagement and uptake within the European quantum industry.

2.Enabling broad stakeholder participation in international standardisation activities (e.g. ISO/IEC, ITU-T, ETSI), promoting EU priorities.

3.Support interoperability and integration of quantum systems through standardisation of interfaces, protocols, and benchmarking methodologies.

4.Develop explanatory documentation and training material to facilitate adoption and implementation of the developed standards.

5.Drafting and developing concrete standards or technical specifications, in cooperation with relevant standardisation bodies, in areas such as:

1.Hardware-software interfaces in quantum computing,

2.Quantum sensing protocols and metrology methods,

3.Control electronics and device modularity for quantum systems,

4.Performance and benchmarking methodologies.

6.Supporting the participation of quantum stakeholders in European and international standardisation organisations (e.g. CEN-CENELEC, ETSI, ISO/IEC, ITU-T)

7.Coordination with existing European and international standardisation organisations to ensure alignment and avoid duplication.

8.Development of support materials such as user guides, training modules, and best practices for the standards developed.

9.Organisation of workshops and consultations with quantum stakeholders (including SMEs, start-ups, and large industry) to ensure inclusivity and consensus building.

The proposal must present a clear plan for stakeholder engagement, deliverables, and budget justification, including person-days per task and daily rates. A single proposal is expected. European standardisation organisations (ESOs) are encouraged to lead or be key partners in the consortium.

HORIZON-CL4-2026-04-DIGITAL-EMERGING-18: Large-Scale Photonic Quantum Computing Platform Technologies (RIA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 10.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 10.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application 130 . In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees. 131

Technology Readiness Level

Activities are expected to start at TRL 4 and achieve TRL 7 by the end of the project – see General Annex B.

Expected Outcome: This action will establish a strategic European initiative to develop scalable, modular, and interoperable photonic quantum computing platforms. Proposals for this topic are expected to address and provide credible solutions to at least two major technical roadblocks currently limiting the advancement of photonic quantum computing such as:

1.The lack of deterministic, high-efficiency photonic entanglement and loss-tolerant architectures suitable for fault-tolerant scaling

2.The absence of a standardised, integrated control stack combining photonic hardware, firmware, and system software with reliable benchmarking across platforms

Project results are expected to contribute to the following expected outcomes:

1.By 2028, demonstration of a photonic NISQ processor with ≥100 photonic qubits, integrating deterministic single-photon sources, low-loss waveguides, on-chip detectors, and a firmware stack (scheduler, controller, compiler), validated via hardware-agnostic benchmarks and hybrid photonic-HPC applications demonstrating classical-quantum crossover

2.By 2030, delivery of a full-stack, high-connectivity photonic quantum computer, with modular scalability, integrated on-chip and fibre-based interconnects, and high-fidelity gates (e.g. error rates ≤10⁻³) with an indicative target of 1 000 photonic qubits, laying the groundwork for prototype demonstrations of quantum utility on industrially relevant workloads.

3.System-level interoperability and standardisation, with published interface specifications across photonic quantum hardware and software stacks including packaging, APIs, compiler interfaces, and cloud protocols compatible with telecom wavelengths

4.Validation of entanglement distribution across modules through standardised protocols and field-demonstration of interconnected photonic quantum processors

5.Acceleration of industrialisation and commercialisation, including a roadmap for pilot manufacturing lines, quality assurance protocols, and development of a sovereign European supply chain for photonic quantum technologies

6.Demonstration of project results through a concrete use case provided by a major end-user partner within the consortium, validating the platform’s relevance and performance under real operational constraints.

Scope: Proposals for this topic are expected to be led by a startup with demonstrated expertise in photonic quantum computing. The startup should collaborate with relevant academic, industrial, and RTO partners to ensure both technological depth and market orientation. The consortium should also include at least one major end-user whose operational needs will shape the platform design, and whose infrastructure will host the field demonstration of the project’s results.

Proposals should implement a coordinated, durable R&I programme that integrates hardware, software, system architecture, and application-level use cases. Activities should include:

1.Platform development advancing open, scalable photonic quantum processors with semiconductor and/or glass-based photonic chips, integrated control electronics, firmware, and robust error mitigation and correction schemes

2.System integration realising modular quantum nodes with photonic interconnects and validating scalable architectures under realistic noise, loss, and control constraints

3.Software stack co-design integrating low-level firmware, compilers, hybrid algorithms, and network APIs to demonstrate application-level quantum advantage and HPC interoperability

Proposals are expected to build upon prior Quantum Flagship results and demonstrate capacity to contribute actively to the governance and strategic coordination of the EU quantum computing ecosystem, including synergies with STEP, Chips JU, IPCEI projects and EuroHPC.

Photonics

Proposals are invited against the following topic(s):

HORIZON-CL4-2027-05-DIGITAL-EMERGING-03: Advanced integrated photonic devices for extended features and ultra-low power consumption (RIA) (Photonics Partnership)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 3.00 and 5.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 25.00 million.

Type of Action

Research and Innovation Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway, associated countries, OECD countries and MERCOSUR countries.

For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, shall not participate in the action.

Technology Readiness Level

Activities are expected to start at TRL 3 and achieve TRL 6 by the end of the project – see General Annex B.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 132 .

Expected Outcome:

1.Advanced integrated photonic devices and circuits with enhanced functionality and performance enabling wider application across multiple sectors including digital, automotive, industrial, health and security

2.Reinforced competitiveness of EU photonics actors by demonstrating advancements in representative system configurations and validating real-world applicability

3.Significantly improved performance of electro-optic systems in applications such as communication, computing, sensing, medical diagnostics, data processing, AI supporting the introduction of photonic elements into such systems

4.Low power consumption sensors with increased performance in application domains

Scope: R&I should enhance the functionality, efficiency, and integration of photonic devices and circuits with a focus extended system performance. Action should address at least two of the following aspects.

1.Enhanced performance through improved spectral purity, wavelength coverage, output power and noise characteristics.

2.Increased modulation or detection speeds going beyond the capability of existing PIC material platforms, improved signal-processing capabilities, and integration of novel materials such as thin-film LiNbO3, BTO, graphene, silicon carbide, phase change materials and TMDCs.

3.Miniaturised, high-complexity photonic circuits (e.g. multilayer photonics, chiplets, multiple integrated functional elements), scalable interconnects and electronics-photonics integration (co-packaged, heterogeneous, or monolithic) to improve performance, reliability, and cost-efficiency.

4.Reduction of power consumption for example through improved electrical-to-optical conversion, lower optical losses, devices operable at higher temperatures to reduce cooling needs, and low-power circuit actuation and control.

Proposals should consider system-level impact and demonstrate advancements in representative configurations relevant to one or more application domains.

This topic implements the co-programmed European Partnership on photonics.

HORIZON-CL4-2026-04-DIGITAL-EMERGING-14: Networking and Future Photonics Strategy (CSA) (Photonics Partnership)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 3.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 3.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: Projects are expected to contribute to the following outcomes:

1.Continued coordination and strategic support to the broader European photonics ecosystem, fostering a transparent, inclusive governance model and bottom-up roadmap development.

2.Strengthened engagement across the photonics ecosystem, including industry, academia, national platforms and end-user sectors.

3.Improved alignment of regional, national and European R&I agendas, enhancing coherence and impact across funding instruments.

4.Effective monitoring and steering of Partnership-funded projects towards the achievement of Key Performance Indicators.

5.Increased visibility of photonics as a critical enabling technology for EU priorities such as the digital and green transitions, industrial competitiveness and technological sovereignty.

6.Enhanced collaboration with other European Partnerships and strategic initiatives to maximise synergies and streamline efforts.

7.Improved access to private and blended finance for photonics innovation, growth and scale-up.

Scope: Proposals should include:

1.Development and regular updating of the European Photonics Strategic Research and Innovation Agenda (SRIA) and associated roadmaps

2.Coordination and monitoring of Partnership-funded R&I and CSA projects, including tracking of Key Performance Indicators and recommending corrective actions where needed

3.Outreach, advocacy, and stakeholder engagement, including alignment with national, regional, and European photonics strategies and input into broader EU policy initiatives

4.Provision of a unified communication platform for the European photonics community and strengthened public communication on the impact of photonics

5.Facilitation of collaboration with other European Partnerships, strategic initiatives, and financial institutions to identify synergies and improve access to innovation financing.

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

Semiconductors

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-04-DIGITAL-EMERGING-15: Strengthening the cooperation of semiconductor-intensive EU regions (CSA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 1.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Expected Outcome: The topic's objective is to support semiconductor-intensive regions and regional industrial semiconductor clusters working with regional governments. The notion of semiconductors includes integrated circuits (chips) with electronic and photonic functionalities.

Regions have an essential role to play in the implementation of EU policies in the field of semiconductors. Within their remit they facilitate establishing industrial activities related to semiconductor production and services by providing for example construction permits, energy, water, infrastructure and often funding. They help creating regional ecosystems around big fabs and contribute to structuring clusters of actors across the value chain.

The expected outcomes are

1.Stronger cooperation of regions (governments and linked industrial clusters) which are active across the semiconductor supply chain

2.Contributions to the smart specialisation of regions in the semiconductor area

3.Maps of regional semiconductor ecosystems across the value chain and their connections amongst each other and identification of common needs

4.A joint strategy to link and strengthen regional semiconductor ecosystems which may possibly lead to increased effectiveness of the Competence Centres originating from the Chips for Europe initiative.

5.A sustainable online platform exchanging information on capabilities and best practices, guiding potential investors and supporting new entrants intending to specialise in semiconductor.

Scope: The action should pursue its objectives by means of

1.Identifying key local actors in the semiconductor supply chain and their common needs

2.Developing a joint strategy to strengthen the cooperation of semiconductor-intensive regions

3.Exploring cooperation with the Chips Competence Centres established under the Chips JU

4.Evidence gathering on obstacles to semiconductor production investments related to framework conditions such as permitting

5.Collecting best practices on overcoming such obstacles and preparing guidelines and their dissemination to the respective regional and national public authorities for accelerating the construction of semiconductor production infrastructures in Europe.

The action should support networking and joint work of the involved stakeholders, such as e.g. those in the European Semiconductor Regions Alliance (ESRA).

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

Other emerging technologies

Proposals are invited against the following topic(s):

HORIZON-CL4-2027-04-DIGITAL-EMERGING-10: Horizon scanning and foresight in future enabling digital technologies (CSA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 4.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 4.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 133 .

Expected Outcome:  

1.European leadership in foresight activities on future enabling technologies and their transformational potential in industrial, societal and environmental terms.

2.Increased collaboration between academia, industry players and other relevant stakeholders in iterative and multidisciplinary approaches for co-creating the enabling technologies of the future.

3.Alignment with national or regional initiatives creating an expanding innovation ecosystem, anchored in local contexts across Europe, for selected emerging technologies.

4.Accelerating the pick-up of novel advanced technology by industry and society.

Scope: Proposals should establish a forum for emerging interdisciplinary areas and new technological visions.

Proposals should enable and support a broad range of participants (across disciplines in science and engineering, RTOs, industry sectors, stakeholders) to meet, mutually inspire, cooperate and develop together innovative ideas for future enabling digital technologies covering from fundamental research up to proof of concept.

Proposals should involve and be driven by representatives of the relevant actors of the field (e.g., academia, RTOs, industry including SMEs).

Proposals should consider civil society engagement for seeking wider input.

Proposals should connect with analogous EC-internal activities, either ongoing (e.g. FOSI4EIC involving EISMEA and JRC) or foreseen, such as the Competitiveness Coordination Tool and the technology observatory envisaged in the FP10 regulation.

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

HORIZON-CL4-2026-04-DIGITAL-EMERGING-17: Fostering 2-Dimensional Materials (2DM) based emerging and enabling technologies (CSA)

Call: DIGITAL

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of around EUR 1.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 1.00 million.

Type of Action

Coordination and Support Actions

Eligibility conditions

The conditions are described in General Annex B. The following exceptions apply:

Subject to restrictions for the protection of European communication networks.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 134 .

Expected Outcome:

1.Maximize the impact of EU-funded R&I in 2DM-based emerging and enabling technologies.

2.Reinforce the related R&I community in Europe.

Scope: Proposals should provide key support functions fostering a dynamic R&I community in 2DM-based emerging and enabling technologies, facilitating synergies and collaboration among relevant EU-funded projects – including those of the Graphene Flagship - and associated entities.

Proposals should provide support to the relevant actors in R&I roadmapping, innovation, standardization activities in 2DM-based technologies

Proposals should establish and keep up-to-date European and global R&I and funding landscapes in 2DM-based technologies.

Proposals should relay and amplify communication and dissemination activities of the actors in the domain of graphene and other 2DMs.

Proposals should foster interactions and synergies with relevant national and regional initiatives, Partnerships, in particular the Innovative advanced materials for Europe partnership, projects such as InnoMatSyn, and infrastructures in the domain.

Beneficiaries that intend to transfer ownership or grant an exclusive licence must formally notify the granting authority (i.e. DG-CNECT and HaDEA) before the intended transfer or licensing takes place and the granting authority may up to four years after the end of the action object to a transfer of ownership or the exclusive licensing of results.

AI for manufacturing and energy-intensive industries

Proposals are invited against the following topic(s):

HORIZON-CL4-2026-02-DIGITAL-EMERGING-51-two-stage: AI improved advanced manufacturing and production processes in factories (RIA) (Made in Europe and AI, Data and Robotics partnerships)

Call: INDUSTRY-two-stage

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.00 and 6.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 30.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

In order to include a business case and exploitation strategy, as outlined in the introduction to Destination 'Leadership in materials and production for Europe', the page limit in part B of the General Annexes is exceptionally extended by 3 pages (for second-stage proposals).

Technology Readiness Level

Activities are expected to start at TRL 4-5 and achieve TRL 6 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

To ensure a balanced portfolio covering also textiles, grants will be awarded to applications not only in order of ranking but at least also to one proposal that is the highest ranked with focus on complex functional and technical textiles, provided that the applications attain all thresholds.

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 135 .

Expected Outcome:

1.Increased competitiveness and productivity, through innovative AI-enabled advanced manufacturing processes and operations, including real-time monitoring and adaptive optimisation; and

2.Reduction of emissions and alignment with Clean Industrial Deal objectives.

Scope: AI approaches in manufacturing processes hold the potential to significantly enhance circularity, process and operational efficiency as well as sustainability of modern factories. Current state-of-the-art technologies have already paved the way for more streamlined operations, yet there remains untapped value in e.g. quality improvement, definition of optimal process operating conditions, reduction of scrap, optimization of energy usage. Real-time monitoring and adaptive optimisation using AI models can enable agile responses to production variability and support sustained, high-performance operations.

New solutions based on innovative enabling technologies such as deep learning, large language models, digital twins, synthetic data, and data-driven models allow manufacturers to improve production system efficiency, elevate product quality, and proactively address critical challenges in energy consumption and carbon footprint. This dual focus on operational excellence and sustainability ensures that factories can maintain competitive advantage while also contributing to specific environmental goals, e.g. reducing the pressure on ecosystems and natural resources. Since innovation capacity and competitiveness also requires a systemic understanding of an organization’s value creating structure, novel AI solutions should be implemented such that they can support all structures and phases of operation, in technical and non-technical terms.

Proposals should produce dedicated innovative explainable AI based solutions in advanced manufacturing for at least two of the following:

1.improve processes and operational efficiency, and reduce climate and environmental impact of processes and factories through dynamic selection of optimal processes and production parameters, exploiting AI for process modelling and/or optimisation;

2.avoid the production of defective parts using AI to detect process drift and anomalies and correct proactively defects in real time; and

3.maximise the fraction of regenerated components or materials used in the production using AI to optimise the material flow.

Proposals should demonstrate potential for these AI tools to adapt to changing production needs and real-time data, and should describe how industrial data access, confidentiality, and secure data-sharing will be addressed.

Projects are encouraged to link with AI Factories, including the Data Labs. The results may be validated in Testing and Experiment Facilities (TEFs), and further deployed via European Digital Innovation Hubs (EDIHs). This topic is linked to the Apply AI Strategy, therefore proposals should seek collaboration with relevant initiatives.

Proposals can optionally address the conditions for implementing the novel AI solutions within an organisations structure and value creating models, thereby contributing to systemic approach of implementing a smart organisation.

This topic is linked to the Apply AI Strategy, therefore proposals should seek collaboration with relevant initiatives.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to Destination ‘Leadership in materials and production for Europe’.

This topic implements the co-programmed European Partnerships Made in Europe and AI, Data and Robotics.

HORIZON-CL4-2027-02-DIGITAL-EMERGING-52-two-stage: New approaches for Human/AI collaboration for the workforce of the future (RIA) (Made in Europe and AI, Data and Robotics partnerships)

Call: INDUSTRY-two-stage

Specific conditions

Expected EU contribution per project

The Commission estimates that an EU contribution of between EUR 4.00 and 6.00 million would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of a proposal requesting different amounts.

Indicative budget

The total indicative budget for the topic is EUR 30.00 million.

Type of Action

Research and Innovation Actions

Admissibility conditions

The conditions are described in General Annex A. The following exceptions apply:

Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).

In order to include a business case and exploitation strategy, as outlined in the introduction to Destination 'Leadership in materials and production for Europe', the page limit in part B of the General Annexes is exceptionally extended by 3 pages (for second-stage proposals).

Technology Readiness Level

Activities are expected to start at TRL 4-5 and achieve TRL 6 by the end of the project – see General Annex B.

Procedure

The procedure is described in General Annex F. The following exceptions apply:

The first-stage proposals of this topic will be evaluated blindly.

Legal and financial set-up of the Grant Agreements

The rules are described in General Annex G. The following exceptions apply:

The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) 136 .

Expected Outcome:

1.Industrial jobs are transformed through AI-based human-machine interactions (and skills linked to them) which enhance flexibility, inclusion, well-being, up-skilling, career evolution and knowledge sharing;

2.Increased competitiveness and sustainability of advanced manufacturing industries by means of knowledge formalization and adaptability of the machines to workers and markets based on different cultures.

Scope: Innovative AI approaches are poised to revolutionise human-machine collaboration in factories by fostering an environment where technology and human expertise synergistically enhance each other. AI can enhance the value of the companies by capturing and formalising the knowledge which is dispersed and not explicit. This allows companies to really own the knowledge and use it to reduce the onboarding time of new employees and support personnel upskilling to adapt to the evolving technological landscape. AI has a great potential to make task simpler by reducing the complexity offering intuitive interfaces and real-time feedback allowing workforce to be more efficient and effective while facilitating access to more complex tasks including those involving various forms of planning. AI can also adapt the interaction of automation with the worker taking into account particular needs of the human, including adaptation to the different abilities of the workers and facilitating inclusion. Finally, AI can be used to allow easier export of automation produced in EU by facilitating its interaction with workforce having different cultures adapting the interaction of the machines to the different needs.

Proposals should produce dedicated innovative AI approaches for human-machine collaboration in advanced manufacturing to be applied in at least two of following fields:

1.Human-AI Co-Learning and knowledge capture to share competences, capture expert knowledge, provide interactive mentoring to up-skill the workforce, and support re-qualification and continuous training – leading to increased knowledge at factory level and avoiding loss of know-how.

2.Human-AI teamwork thanks to innovative natural interaction models (considering the e.g. related hardware interfaces and/or collaborative machine tools), enabling to control complexity in cognitive cooperating production systems, including planning activities at shop floor level.

3.Interfaces with automation which automatically adapt to the need of the humans including different abilities and different cultural needs.

Proposals should integrate a gender perspective and avoid any type of discrimination in the design and deployment of AI systems and human-machine interaction models, including addressing differences in user needs, such as needs of persons with disabilities, physical and cognitive ergonomics and training pathways. Proposals are also expected to identify and address other potential biases in AI systems to promote inclusive design that ensures safe and effective use by all workers. Human/AI collaboration requires utmost sensitivity to and consideration of human values and consideration of ethical principles as represented in Digital Humanism, therefore, appropriate consideration must also be given to the contribution of SSH.

This topic is linked to the Apply AI Strategy, therefore proposals should seek collaboration with relevant initiatives.

In addition, proposals are invited to build on the results of past projects on Extended Reality Technologies (XR), such as HORIZON-CL4-2021-HUMAN-01-13, HORIZON-CL4-2021-HUMAN-01-14, HORIZON-CL4-2021-HUMAN-01-25, HORIZON-CL4-2021-HUMAN-01-06, HORIZON-CL4-2021-HUMAN-01-28.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to Destination ‘Leadership in materials and production for Europe’.

This topic implements the co-programmed European Partnerships Made in Europe and AI, Data and Robotics.

HORIZ